CN110025508A - A kind of essence cream and preparation method thereof preventing striae of pregnancy generation - Google Patents
A kind of essence cream and preparation method thereof preventing striae of pregnancy generation Download PDFInfo
- Publication number
- CN110025508A CN110025508A CN201910311710.9A CN201910311710A CN110025508A CN 110025508 A CN110025508 A CN 110025508A CN 201910311710 A CN201910311710 A CN 201910311710A CN 110025508 A CN110025508 A CN 110025508A
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- Prior art keywords
- pregnancy
- striae
- essence cream
- oil
- prevention
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of essence creams for preventing striae of pregnancy generation, comprising functional component, the functional component is at least one of white pond flower seed oil, Butyrospermum parkii fruit rouge, phytosterol, Ci Agan tree benevolence oil, common milfoil extract, Ba 2672, butcher's broom root extract, Gotu Kola P.E, palmityl tripeptides -5.Effect ingredient in essence cream of the present invention can be very good to play synergistic function, the essence cream enable effectively to prevent the generation of striae of pregnancy, and has the function of desalinating well and repair striae of pregnancy.And the essence cream safe without toxic side effect, easy to use, price is low.Meanwhile invention additionally discloses a kind of preparation methods of essence cream.
Description
Technical field
The present invention relates to a kind of essence cream and preparation method thereof, especially a kind of essence cream for preventing striae of pregnancy generation and its
Preparation method.
Background technique
Striae of pregnancy is one kind of striae distensae, betides during pregnancy, due to the gestational period hormonal influence, divides in the pregnancy period
The change secreted, intradermal elastic force (fiber) is weakened, brittleness increases, and subcutaneous capillary and wall of vein are thinning, expand, and abdomen is swollen in addition
The grand elastic fibers for making skin and collagenous fibres are damaged or are broken, and some width differences, pink or purple different in size occur
Red wavy decorative pattern, shows as the streak skin change of atrophic of chest, abdomen, buttocks and thigh.Early stage shows as
The striped of kermesinus or aubergine, then depigmentation, atrophy, are presented a kind of white or silver color skin damage after finally stable
Evil.Because it seriously destroys the aesthetic requirement of women, the posture in women's postpartum is influenced with physical and mental health and by extensive concern.
The method for dispelling striae of pregnancy common at present includes: essential oil champignon method, and this method course for the treatment of is long, and to beautician's
It is required that high, effect is also not highly desirable；Skin method is changed, using Chemopeel agent, easily causes adverse reaction, chemical substance easily precipitates
On the skin；Laser therapy, or even propose more minimally heart surgery methods.However a large amount of studies have shown that striae of pregnancy is still
It is so a problem, does not find the specific cause of disease not only, does not more establish specific treatment method.
CN109044888A discloses tea-seed oil and dispels striae of pregnancy emollient cream and preparation method thereof, which is
Using tea-seed oil and hEGF as main composition, then be equipped with moisturizer, emulsifier, thickener, PH regulator and
Essence, water are made.The above technology contains existing banned substance hEGF, and there are some potential safety problemss.
CN106860148A discloses a kind of striae of pregnancy repair cream and preparation method thereof, which extracted with Sanguis Draxonis
Object, Europe Flos Caryophylli extract, butter berry extract, zebrawood extract, hyaluronic acid, water, water phase auxiliary agent (glycerol, butanediol, urine
One of Bursin and EDTA.2Na or more than one) and oily phase auxiliary agent (horse fat, ceteareth -10, cetostearyl alcohol
With one of jojoba oil or more than one) composition.But the above technology repairing effect is bad.
CN106265310A discloses prevention striae of pregnancy composition and striae of pregnancy frost and preparation method thereof, but its effect is not
It is ideal.There are many disadvantages due to carrying out eliminating to it again after striae of pregnancy generates, there is an urgent need to not yet generate gestation
When line, one kind is provided and is able to maintain skin elasticity and softness, enhanced skin tensile resistance and can nourish and repair skin
The striae of pregnancy essence cream for preventing striae of pregnancy generation.
Currently, treating the product of striae of pregnancy in the market, wherein relatively effective is anti-striae of pregnancy frost, but the similar drug is easy
Liver is damaged, long-time service can generate drug resistance, inconvenient to use, airtight, on the high side etc. there are administration time length, carrying
Disadvantage；And prevention striae of pregnancy effect is poor, undesirable.Therefore, it is badly in need of a kind of easy to use, safe, cheap prevention gestation
The good product of line effect.
Summary of the invention
Based on this, is provided it is an object of the invention to overcome in place of above-mentioned the deficiencies in the prior art and a kind of prevent striae of pregnancy
The essence cream of generation.
To achieve the above object, the technical solution used in the present invention are as follows: a kind of essence cream for preventing striae of pregnancy generation, packet
Containing functional component, the functional component is white pond flower seed oil, Butyrospermum parkii fruit rouge, phytosterol, Ci Agan tree benevolence oil, Europe alpine yarrow
At least one of careless extract, Ba 2672, butcher's broom root extract, Gotu Kola P.E, palmityl tripeptides -5.
Applicant passes through a large amount of exploration discoveries, and effect ingredient in the application can be good at playing synergistic function,
Achieve the effect that preferably to prevent striae of pregnancy generation, in which:
White pond flower seed oil: due to having the long chain fatty acids of oxidation resistant effect containing 98% or more, so it is the world
One of upper most stable of vegetable oil.White pond flower seed oil can be used as cosmetic base grease；Molting hormone has in white pond flower seed oil
Water loss, regeneration skin are prevented, is skin metabolism activator；It is adjusted by changing keratin tissue
The exudation of water and compound reuptakes moisture and forms hydrate in epidermal layer cells to lock moisture in skin epidermis.
Butyrospermum parkii fruit rouge: shea butter, it is most effective natural moisture preserving product that the soft and moist children of quality is sliding, promotes cytothesis
It the effect of with skin moisture film is repaired, tender can soothe the skin.It is very close with human secretory grease index.Contain pole abundant
The non-saponified ingredient being easily absorbed by the human body.Protective film, moisturizing, sunscreen protection obvious effect are formed in skin surface.
Phytosterol: phytosterol can help softening skin, stimulate pore toxin expelling, restore natural lipid barrier.
The dry tree benevolence oil of Ci A: thorn A Ganshu benevolence oil contains abundant fatty acid, sterol, vitamin e and phenolic compound.Wherein
Including a large amount of essential fatty acid, unsaturated fatty acid and linoleic acid, it is that these cannot all be synthesized in human body and must be from rouge
It is acquired in fat.Fatty acid maintains the hydration levels of human health, and linoleic acid application confrontation hair on the skin is pointed out in research
Inflammation reduces acne, has positive effect on moisture-keeping functions；And to can lead to skin too early for the shortage of essential unsaturated fatty acid
Aging and wrinkle.
Common milfoil extract: sensitivity phenomenon can be effectively soothed the skin, is promoted blood circulation.
Ba 2672: being the most important ingredient for mitigating inflammation in conker, it is by filling up veinlet and hair
Thin blood vessel microscopic nicks and subtle visible gap, can effectively improve the integrality of blood vessel astillen, can play promote blood circulation,
Promote wound healing, antioedematous, it is anti-inflammatory it is impervious go out with vascular protection act on.
Gotu Kola P.E: centella can be made skin limber up, be helped to solve with compact epidermis and corium coupling part
Certainly cutis laxa phenomenon (especially postpartum mother), keeps skin smooth flexible；Help promotes collagen in skin corium to be formed, and makes
Fibrin regeneration, reconnect get up, are inherently eliminated mother's line, achieve the effect that skin compact smooth.It can also help
Help impaired organization healing and consolidation skin.
Palmityl tripeptides -5: promoting to generate collagen, while collagen being protected not decomposed by matrix metalloproteinase,
The two synergistic effect, effectively removes wrinkle, improves skin quality.
Preferably, the functional component includes white pond flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence oil, palmityl three
Peptide -5.Applicant passes through a large amount of exploration discoveries, and when the functional component includes above-mentioned four kinds of ingredients, above-mentioned four kinds of ingredients can be very
Good performance synergistic function makes the essence cream have the effect of preventing striae of pregnancy generation well.
It is highly preferred that the weight of the white pond flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence oil, palmityl tripeptides -5
Than are as follows: white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl tripeptides -5=(0.1~2): (1~5): (1~
5): (1~5).Applicant passes through a large amount of exploration discoveries, when the functional component has above-mentioned weight ratio, above-mentioned four kinds of ingredients
Synergistic function can be preferably played, the essence cream is made to have the effect of preferably preventing striae of pregnancy generation.
It is highly preferred that the weight of the white pond flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence oil, palmityl tripeptides -5
Than are as follows: white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl tripeptides -5=1:3:3:3.Applicant is through excessive
Exploration discovery is measured, when the functional component has above-mentioned weight ratio, above-mentioned four kinds of ingredients can preferably play synergistic work
With making the essence cream have the effect of preferably preventing striae of pregnancy generation.
Preferably, the essence cream that the described prevention striae of pregnancy generates, also includes moisturizer, and the moisturizer is glycerol, 1,
At least one of 3-propanediol, pungent glycol, Sensiva SC50.
Preferably, the essence cream that the prevention striae of pregnancy generates, also includes chelating agent, preservative, thickener.
It is highly preferred that the chelating agent is EDETATE SODIUM；The preservative is parahydroxyacet-ophenone, in 1,2- hexylene glycol
It is at least one；The thickener is at least one of ammonium acryloyl taurate/VP copolymer, xanthan gum.
Preferably, the essence cream that the prevention striae of pregnancy generates, also includes grease, and the grease is that caprylic/capric is sweet
Oily three esters, isononyl isononanoate, dimethyl silicone polymer, cetostearyl alcohol, cetostearyl alcohol olive oleate, the smooth olive of sorb
At least one of oleate, C14-22 alcohol, C12-20 alkyl glucoside, tocopherol acetate.
Meanwhile the present invention also provides a kind of preparation methods of essence cream that the prevention striae of pregnancy generates, including walk as follows
It is rapid:
(1) preparation of water phase: water, moisturizer, chelating agent, preservative, thickener are added in water phase pot, are dispersed with stirring
It is even, it is heated to 80-85 DEG C, homogeneous keeps the temperature, defoams, is spare to being completely dispersed；
(2) preparation of oily phase: grease, effect ingredient in addition to Ci Agan tree benevolence oil are added in oily phase pot, 80- is heated to
It 85 DEG C, is uniformly mixed；
(3) oil is added in water phase, while opens homogeneous, until emulsification uniformly, obtains mixed liquor completely；
(4) liquid to be mixed is cooled to 60 DEG C, and Ci Agan tree benevolence oil is added, and homogeneous stirs evenly, cools down after defoaming；It is cooled to
45 DEG C hereinafter, the essence cream generated up to the prevention striae of pregnancy.
Preferably, in the step (1), the revolving speed of stirring is 600-800r/min, and the time of stirring is 10-20min；Institute
It states in step (2), the revolving speed of stirring is 600-800r/min, and the time of stirring is 10-15min；In the step (3), homogeneous
Revolving speed be 8000-10000r/min, time of stirring is 3-5min.
Compared with the existing technology, the invention has the benefit that
Effect ingredient in essence cream of the present invention can be very good to play synergistic function, make the essence cream
The generation of striae of pregnancy can effectively be prevented, and have the function of desalinating well and repair striae of pregnancy.And the essence cream peace
Easy to use completely without toxic side effect, price is low.
Specific embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.Furthermore.It should be noted that the restriction for focusing on functional component of the invention, as moisturizer, chelating
The concrete content of agent, preservative, thickener etc., the present invention in have no specific restriction, those skilled in the art can be according to practical need
Carry out general adjustment.
Embodiment 1
A kind of embodiment for the essence cream that prevention striae of pregnancy of the present invention generates, essence cream described in the present embodiment include with
The ingredient of lower mass percentage:
A phase: water 43.85%, glycerol 6%, EDETATE SODIUM 0.05%, 1,2- hexylene glycol 0.3%, parahydroxyacet-ophenone
0.3%, ammonium acryloyl taurate/VP copolymer 0.5%, xanthan gum 0.15%；
B phase: caprylic/capric triglyceride 8%, isononyl isononanoate 5%, dimethyl silicone polymer 6%, cetostearyl alcohol
0.5%, white pond flower seed oil 1%, saualane 5%, beeswax 2%, Butyrospermum parkii fruit rouge 3%, phytosterol 1%, cetearyl alcohol
The smooth olive oleate 1% of alcohol olive oleate 1%, sorb, C14-22 alcohol 0.5%, C12-20 alkyl glucoside 0.5%, fertility
Phenol acetic acid esters 1%；
C phase: Ci Agan tree benevolence oil 3%, sodium acrylate/acryloyldimethyl taurate copolymer 0.2%, isohexadecane
0.1%, polysorbate 0.2%；
D phase: 1,3-PD 0.3%, pungent glycol 0.2%, Sensiva SC50 0.2%, decoyl hydroximic acid 0.1%, rose
Rare caul-fat 0.05%, common milfoil extract 3%, Gotu Kola P.E 3%, palmityl tripeptides -5 3%.
Essence cream described in the present embodiment is prepared by the following method gained:
(1) A phase constituent is added in water phase pot, stirring (600-800r/min, 10-20min) is uniformly dispersed, and is heated to
80-85 DEG C, homogeneous is heat preservation 30min, defoaming, spare to being completely dispersed；
(2) B phase constituent is added in oily phase pot, is heated to 80-85 DEG C, stirring (600-800r/min, 10-15min) is mixed
It closes uniform；
(3) B is added in A phase, while opens homogeneous, 8000-10000r/min, 3-5min, until emulsification is equal completely
It is even, obtain mixed liquor；
(4) liquid to be mixed is cooled to 60 DEG C, and C phase is added, and homogeneous stirs evenly, cools down after defoaming；Be cooled to 45 DEG C hereinafter,
D phase is added, stirs the essence cream generated to get the prevention striae of pregnancy.
Embodiment 2
A kind of embodiment for the essence cream that prevention striae of pregnancy of the present invention generates, the preparation of essence cream described in the present embodiment
Method is with embodiment 1, and specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: the content of palmityl tripeptides -5 is not
Together；In essence cream described in the present embodiment (in terms of mass percentage) white pond flower seed oil 0.1%, Butyrospermum parkii fruit rouge 1%, Ci A
Sweet tree benevolence oil 1%, palmityl tripeptides -5 1%.
Embodiment 3
A kind of embodiment for the essence cream that prevention striae of pregnancy of the present invention generates, the preparation of essence cream described in the present embodiment
Method is with embodiment 1, and specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: the content of palmityl tripeptides -5 is not
Together；In essence cream described in the present embodiment (in terms of mass percentage) white pond flower seed oil 2%, Butyrospermum parkii fruit rouge 5%, Ci Agan
Set benevolence oil 5%, palmityl tripeptides -5 5%.
Comparative example 1
A kind of preparation preventing striae of pregnancy essence cream:
The preparation method is the same as that of Example 1, specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl three
The amount of peptide -5 is different.
Specially white pond flower seed oil 0%, Butyrospermum parkii fruit rouge 3%, Ci Agan tree benevolence oil 3%, palmityl tripeptides -5 3%.
Comparative example 2
A kind of preparation preventing striae of pregnancy essence cream:
The preparation method is the same as that of Example 1, specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl three
The amount of peptide -5 is different.
Specially white pond flower seed oil 1%, Butyrospermum parkii fruit rouge 0%, Ci Agan tree benevolence oil 3%, palmityl tripeptides -5 3%.
Comparative example 3
A kind of preparation preventing striae of pregnancy essence cream:
The preparation method is the same as that of Example 1, specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl three
The amount of peptide -5 is different.
Specially white pond flower seed oil 1%, Butyrospermum parkii fruit rouge 3%, Ci Agan tree benevolence oil 0%, palmityl tripeptides -5 3%.
Comparative example 4
A kind of preparation preventing striae of pregnancy essence cream:
The preparation method is the same as that of Example 1, specially white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree benevolence oil: palmityl three
The amount of peptide -5 is different.
Specially white pond flower seed oil 1%, Butyrospermum parkii fruit rouge 3%, Ci Agan tree benevolence oil 3%, palmityl tripeptides -5 0%.
Embodiment 4
Skin irritation/corrosion test (multiple skin irritation test) and Product Safety evaluation
Skin irritation/corrosion test (the multiple skin irritatin for the essence cream that prevention striae of pregnancy of the present invention generates
Property experiment) according to " cosmetics health specification " (2007 editions) skin irritation/corrosion test carry out test evaluation, safety
Evaluation is evaluated according to the experiment of " cosmetics safety technical specification " (2015 editions) human body patch, and evaluation result shows multiple skin
Irritant test result be it is non-stimulated, patch test results are feminine gender.
Embodiment 5
Skin elasticity test:
Subject: 120 30-50 years old healthy womens are randomly divided into 8 groups, average every group of 15 people
Sample and grouping: the sample of selection example 1-3 and comparative example 1-4 are used as and give sample group, while blank control is arranged
Group.
Test equipment: the skin elasticity Cotometer of German Courage+Khazaka company (German CK company) manufacture
MPA580 host, used probe are Reviscometer RV600 elastic fibrous tissue test probes.
Test operation:
Blank R2, R5, R7 value of 30min after face area cleans first is tested, wherein R2=Ua/Uf, R5=Ur/Ue, R7
=Ur/Uf,
Ua: the recovery value of skin when from cancellation negative pressure to follow-on test skin surface repressurization next time；
Uf: skin maximum amount of tension when having negative pressure；
Ur: after cancelling negative pressure 0.1s, the recovery value and visco-elastic portions value or plastic value of skin；
Ue: after constant negative pressure is added on skin, the amount of tension of skin, positioning elastic part amount of tension when 0.1s；
R2: the springback capacity of skin and the ratio between maximum tension amount when having a negative pressure when no negative pressure, ratio illustrates skin closer to 1
Skin elasticity is better.
R5: elastic part in skin recovery process with plus negative pressure process the ratio between elastic part, the bigger explanation of the parameter
Skin resilience is better.
R7: the ratio between the maximum tension amount of skin in the elastic part of skin recovery process and cyclic process, ratio is closer
1, illustrate that skin elasticity is better.
Then sample is spread evenly across test zone, twice a day, adhere to sooner or later using, must not use other makeup
Product are used continuously 4 weeks, respectively skin R2, R5, R7 value of the test record test area before and after to sample.The same subject's
Test is completed by the same survey crew.
Test result: improve the elasticity of skin by comparing to skin R2, R5, R7 value variation before and after sample to assess product
Effect, specific R2, R5, R7 value situation of change are as shown in table 1 below:
Situation of change of 1 each group of table to skin R2/R5/R7 value before and after sample
Note: for R2/R5/R7 value closer to 1, skin elasticity is better.
By data in table 1 it is found that embodiment 1-3 test group is surveyed using after 4 weeks in the identical situation of activity component concentration
Skin R2, R5, R7 value obtained lacks any white pond flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence oil, palmityl than comparative example
The value that -5 component of tripeptides measures is high, and as increase R2, R5, R7 value change rate of effective component in embodiment increases, shows it
The effect of improving skin elasticity best, white pond flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence is oily, -5 each group of palmityl tripeptides
Divide and shows significantly to act synergistically.But when each group component continues to be increased to the amount of embodiment 3, R2, R5, R7 value change rate increase
It compares greatly and is not obvious compared with embodiment 1, and economic cost can be greatly increased, while will increase irritation, reduce skin sense, therefore,
Comprehensively consider effect, skin sense, economic cost, embodiment 1 is optimal proportion.
Embodiment 6
To the practical observation of prevention striae of pregnancy
To formation shape of 160 subjects from the 14th pregnant week during 8 weeks after childbirth for striae of pregnancy
Condition is observed, and with the product of above-described embodiment 2 carried out for daily 1-2 times at abdomen, chest and thigh using.
Initial in research: 80% subject does not have striped, and 20% subject has striped, and (wherein 10% subject has gently
Striped is spent, 5% there are a large amount of slight stripeds, and 5% there are a large amount of strong stripeds).Have in these subjects 80% it is artificial first secondary
It educates (wherein 3.5% has striped), 20% is repeatedly fertility (wherein 15% has striped).
The resulting result after the observation period are as follows: 65% subject does not generate striae of pregnancy, and 20% subject has slight item
Line, 10% subject generates a large amount of strong stripeds of subject's generation of a large amount of slight stripeds and 5%, from above-mentioned test result
It can be seen that prevention striae of pregnancy product of the invention can prevent the generation of striae of pregnancy well, and there is a degree of subtract
The effect of light striae of pregnancy.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than protects to the present invention
The limitation of range is protected, although the invention is described in detail with reference to the preferred embodiments, those skilled in the art should
Understand, it can be with modification or equivalent replacement of the technical solution of the present invention are made, without departing from the essence of technical solution of the present invention
And range.
Claims (10)
1. a kind of essence cream for preventing striae of pregnancy generation, which is characterized in that include functional component, the functional component is Bai Chihua
Seed oil, Butyrospermum parkii fruit rouge, phytosterol, Ci Agan tree benevolence oil, common milfoil extract, Ba 2672, phyllodium tree root mention
Take at least one of object, Gotu Kola P.E, palmityl tripeptides -5.
2. the essence cream that prevention striae of pregnancy generates as described in claim 1, which is characterized in that the functional component includes white pond
Flower seed oil, Butyrospermum parkii fruit rouge, Ci Agan tree benevolence oil, palmityl tripeptides -5.
3. the essence cream that prevention striae of pregnancy generates as claimed in claim 2, which is characterized in that the white pond flower seed oil, butter
Fruit tree fruit rouge, Ci Agan tree benevolence oil, palmityl tripeptides -5 weight ratio are as follows: white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree
Benevolence oil: palmityl tripeptides -5=(0.1~2): (1~5): (1~5): (1~5).
4. the essence cream that prevention striae of pregnancy generates as claimed in claim 3, which is characterized in that the white pond flower seed oil, butter
Fruit tree fruit rouge, Ci Agan tree benevolence oil, palmityl tripeptides -5 weight ratio are as follows: white pond flower seed oil: Butyrospermum parkii fruit rouge: Ci Agan tree
Benevolence oil: palmityl tripeptides -5=1:3:3:3.
5. the essence cream generated such as the described in any item prevention striaes of pregnancy of Claims 1 to 4, which is characterized in that also include moisturizing
Agent, the moisturizer are at least one of glycerol, 1,3-PD, pungent glycol, Sensiva SC50.
6. the essence cream generated such as the described in any item prevention striaes of pregnancy of Claims 1 to 4, which is characterized in that also comprising chelating
Agent, preservative, thickener.
7. the essence cream that prevention striae of pregnancy generates as claimed in claim 6, which is characterized in that the chelating agent is EDTA bis-
Sodium；The preservative is at least one of parahydroxyacet-ophenone, 1,2- hexylene glycol；The thickener is acryloyldimethyl ox
At least one of ichthyodin/VP copolymer, xanthan gum.
8. the essence cream generated such as the described in any item prevention striaes of pregnancy of Claims 1 to 4, which is characterized in that it also include grease,
The grease is caprylic/capric triglyceride, isononyl isononanoate, dimethyl silicone polymer, cetostearyl alcohol, cetostearyl alcohol
The smooth olive oleate of olive oleate, sorb, C14-22 alcohol, C12-20 alkyl glucoside, at least one in tocopherol acetate
Kind.
9. a kind of preparation method for preventing the essence cream that striae of pregnancy generates as described in any one of claim 1~8, feature exist
In including the following steps:
(1) preparation of water phase: water, moisturizer, chelating agent, preservative, thickener are added in water phase pot, are dispersed with stirring uniformly,
It is heated to 80-85 DEG C, homogeneous keeps the temperature, defoams, is spare to being completely dispersed；
(2) preparation of oily phase: grease, effect ingredient in addition to Ci Agan tree benevolence oil are added in oily phase pot, 80-85 is heated to
DEG C, it is uniformly mixed；
(3) oil is added in water phase, while opens homogeneous, until emulsification uniformly, obtains mixed liquor completely；
(4) liquid to be mixed is cooled to 60 DEG C, and Ci Agan tree benevolence oil is added, and homogeneous stirs evenly, cools down after defoaming；It is cooled to 45 DEG C
Hereinafter, the essence cream generated up to the prevention striae of pregnancy.
10. the preparation method for the essence cream that prevention striae of pregnancy generates as claimed in claim 9, which is characterized in that the step (1)
In, the revolving speed of stirring is 600-800r/min, and the time of stirring is 10-20min；In the step (2), the revolving speed of stirring is
600-800r/min, the time of stirring are 10-15min；In the step (3), the revolving speed of homogeneous is 8000-10000r/min,
The time of stirring is 3-5min.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111631964A (en) * | 2020-06-17 | 2020-09-08 | 广州欧盛化妆品有限公司 | Striae gravidarum repair cream and preparation method thereof |
| FR3126876A1 (en) * | 2021-09-15 | 2023-03-17 | Lsi Silderma Ltd | Composition for preventing and/or treating white stretch marks |
| CN115998654A (en) * | 2022-12-29 | 2023-04-25 | 上海萧雅生物科技股份有限公司 | A variety of peptide cosmetic composition with anti-wrinkle effect and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069043A (en) * | 2014-07-23 | 2014-10-01 | 上海岚瑞电子商务有限公司 | Massage gel for preventing striae gravidarum and preparation method thereof |
| CN104997670A (en) * | 2015-07-03 | 2015-10-28 | 北京枫华草木洗涤用品有限公司 | Pure natural moisturizing cream for preventing striae gravidarum |
| CN108904320A (en) * | 2018-09-20 | 2018-11-30 | 深圳市维琪医药研发有限公司 | A kind of peptide composition of prevention and improvement striae of pregnancy |
-
2019
- 2019-04-16 CN CN201910311710.9A patent/CN110025508B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104069043A (en) * | 2014-07-23 | 2014-10-01 | 上海岚瑞电子商务有限公司 | Massage gel for preventing striae gravidarum and preparation method thereof |
| CN104997670A (en) * | 2015-07-03 | 2015-10-28 | 北京枫华草木洗涤用品有限公司 | Pure natural moisturizing cream for preventing striae gravidarum |
| CN108904320A (en) * | 2018-09-20 | 2018-11-30 | 深圳市维琪医药研发有限公司 | A kind of peptide composition of prevention and improvement striae of pregnancy |
Non-Patent Citations (3)
| Title |
|---|
| 天津盛世永业科技发展有限公司: ""十月天使舒纹防护乳"", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20180522105832FJ7DO&NID=20180522105832FJ7DO》 * |
| 广州林森黛化妆品有限公司: ""娅丝圣黛肌肽丝滑特润霜"", 《HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20180427143032JOROA&NID=20180427143032JOROA》 * |
| 王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
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| CN111631964A (en) * | 2020-06-17 | 2020-09-08 | 广州欧盛化妆品有限公司 | Striae gravidarum repair cream and preparation method thereof |
| FR3126876A1 (en) * | 2021-09-15 | 2023-03-17 | Lsi Silderma Ltd | Composition for preventing and/or treating white stretch marks |
| EP4151202A1 (en) | 2021-09-15 | 2023-03-22 | LSI Silderma Ltd | Composition for preventing and/or treating white stretch marks |
| CN115998654A (en) * | 2022-12-29 | 2023-04-25 | 上海萧雅生物科技股份有限公司 | A variety of peptide cosmetic composition with anti-wrinkle effect and preparation method thereof |
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