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CN110023484A - 一种假小链状双歧杆菌及其培养方法和应用 - Google Patents

一种假小链状双歧杆菌及其培养方法和应用 Download PDF

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Publication number
CN110023484A
CN110023484A CN201680091077.1A CN201680091077A CN110023484A CN 110023484 A CN110023484 A CN 110023484A CN 201680091077 A CN201680091077 A CN 201680091077A CN 110023484 A CN110023484 A CN 110023484A
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vacation
bifidobacterium catenulatum
small
pharmaceutical composition
small bifidobacterium
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CN110023484B (zh
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邹远强
薛文斌
肖亮
李晓平
余靖宏
刘传
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BGI Shenzhen Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/02—Acetobacter

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
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  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Molecular Biology (AREA)
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  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

提供了一种假小链状双歧杆菌及其培养方法和应用，该假小链状双歧杆菌（Bifidobacterium pseudocatenulatum）TM12‑14，保藏于广东省微生物菌种保藏中心，其保藏编号为GDMCC No:60089。该菌株能够显著改善溃疡性结肠炎小鼠的表现状态，降低小鼠疾病活动指数和炎症性反应，同时具有降低胆固醇的能力。

Description

PCT国内申请，说明书已公开。

Claims (15)

  1. PCT国内申请，权利要求书已公开。
CN201680091077.1A 2016-12-20 2016-12-20 一种假小链状双歧杆菌及其培养方法和应用 Active CN110023484B (zh)

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PCT/CN2016/111026 WO2018112739A1 (zh) 2016-12-20 2016-12-20 一种假小链状双歧杆菌及其培养方法和应用

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110331119A (zh) * 2019-08-19 2019-10-15 江南大学 两歧双歧杆菌ccfm1063及其应用
WO2024066079A1 (zh) * 2022-09-28 2024-04-04 中国科学院深圳先进技术研究院 防治炎症性肠病的胆汁酸代谢菌及其应用

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113943682B (zh) * 2020-11-12 2023-07-04 江南大学 缓解便秘的长双歧杆菌长亚种及其制备的发酵食品与益生菌制剂
CN113897302B (zh) * 2021-08-06 2022-08-09 东北农业大学 一种可缓解结肠炎的双歧杆菌及其应用
WO2023118868A1 (en) * 2021-12-21 2023-06-29 Quadram Institute Bioscience Bifidobacterium and compositions thereof for breast cancer treatment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103619343A (zh) * 2010-12-07 2014-03-05 高等科学研究委员会 双歧杆菌cect7765及其在预防和/或治疗超重、肥胖和相关病理中的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002329043A1 (en) * 2001-07-30 2003-02-24 Claudio De Simone Treatment of radiation-induced diarrhea with probiotics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103619343A (zh) * 2010-12-07 2014-03-05 高等科学研究委员会 双歧杆菌cect7765及其在预防和/或治疗超重、肥胖和相关病理中的用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ALESSANDRA BORDONI等: "Cholesterol-lowering probiotics: in vitro selection and in vivo testing of bifidobacteria", 《APPL MICROBIOL BIOTECHNOL》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110331119A (zh) * 2019-08-19 2019-10-15 江南大学 两歧双歧杆菌ccfm1063及其应用
CN110331119B (zh) * 2019-08-19 2022-04-29 江南大学 两歧双歧杆菌ccfm1063及其应用
WO2024066079A1 (zh) * 2022-09-28 2024-04-04 中国科学院深圳先进技术研究院 防治炎症性肠病的胆汁酸代谢菌及其应用

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WO2018112739A1 (zh) 2018-06-28

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