CN109998933A - A kind of tooth whitening gel and preparation method thereof, application method - Google Patents

Abstract

The invention provides a tooth whitening gel and a preparation method and a use method thereof, which solves the problem that in the existing tooth whitening methods, in order to achieve a better effect, the use of a higher concentration of peroxide, and the laser with a longer wavelength make people's teeth uncomfortable or Tooth damage problem. The present invention adopts low-concentration (3%-10%) peroxide as the main component of the whitening agent, and at the same time utilizes the catalytic effect of non-metal ions doped with titanium dioxide with a large red shift of visible light, and a blue laser light source of 450±10 nm or Under the irradiation of 405±5nm violet laser light source, the peroxide is rapidly decomposed by photochemical catalysis, so that the low concentration of peroxide can generate enough free radicals to achieve the purpose of teeth whitening.

Description

A kind of tooth whitening gel and preparation method and use method thereof

technical field

The invention relates to the technical field of oral care, in particular to a tooth whitening gel, a preparation method and a use method thereof.

Background technique

The commonly used method of tooth whitening is to apply a substance containing peroxide on the surface of the tooth, and then use the heat generated by the strong light to catalyze the peroxide, so that the peroxide is decomposed under the thermal effect to generate free radicals, thereby whitening the teeth. However, this method has many drawbacks: 1) Dental clinics generally use high concentrations (20%-40%) of peroxides to achieve better whitening effects. Repeated smearing leads to increased tooth discomfort, causing a series of Oral problems, such as symptoms of tooth sensitivity, damage to the mechanical hardness of the enamel surface, and discomfort of the periodontal tissue; 2) The light source used in combination (for example, a laser with a wavelength of 980nm and 808nm) irradiates the peroxide on the tooth surface, The temperature of the teeth will continue to rise, and when the temperature of the teeth is too high, it is easy to cause irreversible damage to the teeth; 3) Low concentrations of peroxides (less than 10%) are generally only suitable for household teeth whitening, and need to be used multiple times before There may be teeth whitening effect, and the effect is not significant and relatively inefficient.

SUMMARY OF THE INVENTION

The purpose of the present invention is to solve the shortcomings of using a higher concentration of peroxide in order to achieve better effects in the existing teeth whitening methods, and the shortcomings of the laser with a longer wavelength that make people's teeth uncomfortable or damage the teeth, and provide a Teeth whitening gel and preparation method and use method thereof. The tooth whitening gel avoids or reduces people's tooth discomfort or tooth damage as much as possible while improving the color level of the teeth, and is safer and more efficient.

To achieve the above object, the technical solution provided by the present invention is:

A tooth whitening gel, which is special in that it includes a whitening agent;

The whitening agent includes 30 to 100 parts of peroxide, 0.5 to 10 parts of non-metal ion-doped titanium dioxide, 15 to 20 parts of a binder, and 450 to 540 parts of purified water.

Further, the peroxide is one or more combinations of hydrogen peroxide, urea peroxide, and perborate; the non-metal ion-doped titanium dioxide is nitrogen-doped titanium dioxide, carbon-doped titanium dioxide One or a combination of the two titanium dioxides.

Further, in order to prolong the service life of the whitening agent, the whitening agent further includes 100 to 150 parts of a stabilizer and 160 to 250 parts of a moisturizing agent.

Further, in order to improve the use experience of patients, to avoid discomfort when teeth whitening, and to optimize the quality of the teeth whitening gel, the teeth whitening gel also includes a catalytic care agent, and the whitening agent and the catalytic care agent are individually packaged. The catalytic care agent comprises 32 to 40 parts of adhesive, 330 to 350 parts of moisturizing agent, 20 to 50 parts of stabilizer, 5 to 10 parts of flavoring agent, and 65 to 75 parts of anti-caries and desensitization. agent, 9 to 14 parts of preservative, 35 to 45 parts of pH adjuster, 450 to 500 parts of purified water.

Further, the stabilizer is one or more combinations of disodium EDTA, sodium hydrogen phosphate and citric acid;

The moisturizing agent is one or more combinations of glycerin, polyethylene glycol, and propylene glycol;

The binder is one or more combinations of sodium carboxymethyl cellulose, carbomer, poloxamer or gelatin;

The flavoring agent is menthol, or use other flavoring agents, such as lemon extract;

The anti-caries desensitizer is one or a combination of strontium chloride, fluoride and potassium nitrate;

The preservative is one or more combinations of sodium benzoate, methylparaben, and ethylparaben;

The pH adjusting agent is one of sodium citrate and potassium citrate or a combination of the two.

Further, the whitening agent includes 60 parts of hydrogen peroxide and 1 part of nitrogen-doped titanium dioxide. Under this active ingredient ratio, combined with light, the optimal tooth whitening effect can be achieved, and the change value of the tooth color before and after use is the largest. .

The present invention also provides a preparation method of a tooth whitening gel, the special feature of which is that the preparation method of the whitening agent is as follows:

Step 1) fully dissolving 30 to 100 parts of peroxide and 0.5 to 10 parts of non-metal ion doped titanium dioxide in 450 to 540 parts of purified water to obtain a solution;

Step 2) Slowly add 15 to 20 parts of the adhesive to the solution, stir evenly, and let stand for 1 to 2 minutes to obtain a whitening agent.

Further, also include the preparation method of catalytic care agent; The preparation method of described catalytic care agent is as follows:

S1) Dissolve 9 to 14 parts of preservative, 20 to 50 parts of stabilizer, 65 to 75 parts of anti-caries desensitizer, and 35 to 45 parts of pH adjuster in 450 to 500 parts of purified water, and mix well , to get a solution;

S2) 5 parts to 10 parts of correctives are added to 330 parts to 350 parts of moisturizing agents, and after fully dissolving, they are added to the solution described in S1);

S3) Add 32 parts to 40 parts of adhesive to the solution obtained in S2), stir evenly, and let stand for 1 min to 2 min to obtain a catalytic care agent.

Further, the specific steps of step 2) are: slowly adding 100 parts to 150 parts of stabilizer, 160 parts to 250 parts of moisturizing agent and 15 parts to 20 parts of adhesive to the solution, stirring evenly, and letting stand 1min to 2min to obtain a whitening agent.

The use method of the above-mentioned tooth whitening gel is characterized in that,

Step 1: Apply the whitening agent on the surface of the patient's teeth to form a coating layer with a thickness of 1mm to 2mm;

In step 2, use a blue laser light source with a wavelength of 450±10nm or a purple laser light source with a wavelength of 405±5nm to irradiate the patient's teeth for 10-30min;

Step 3 Remove the coating from the surface of the patient's teeth.

Preferably, in step 1, the whitening agent is smeared on the surface of the patient's teeth to form a coating layer with a thickness of 2 mm;

In step 2, use a blue laser light source with a wavelength of 450±10 nm to irradiate the patient's teeth for 30 minutes.

Or use in combination with a catalyst conditioner as follows:

Step (1) mix the whitening agent and the catalytic care agent evenly according to the weight ratio of 1:1 to 1.5, and apply it to the surface of the patient's teeth to form a coating layer with a thickness of 1 mm to 2 mm;

Step (2) using a blue laser light source with a wavelength of 450 ± 10 nm or a purple laser light source with a wavelength of 405 ± 5 nm to irradiate the patient's teeth for 10 to 30 minutes;

Step (3) removes the coating layer on the surface of the patient's teeth.

Preferably, in step (1), the whitening agent and the catalytic care agent are uniformly mixed in a weight ratio of 1:1, and applied to the surface of the patient's teeth to form a coating layer with a thickness of 2 mm.

In step (2), a blue laser light source with a wavelength of 450±10 nm is used to irradiate the patient's teeth for 30 minutes.

Principle of the present invention:

A low concentration (3%-10%) of peroxide is used as the main component of the whitening agent, and at the same time, the catalytic effect of non-metal ion-doped titanium dioxide (preferably, nitrogen-doped titanium dioxide with a larger visible light red shift) is used. Under the irradiation of a blue laser light source of ±10nm or a purple laser light source of 405±5nm, the peroxide is rapidly decomposed by photochemical catalysis, so that the low concentration of peroxide can generate enough free radicals to achieve the purpose of tooth whitening.

Semiconductor nano-titanium dioxide, as a new type of catalyst, has a wide range of uses. It is a chemically stable and non-toxic material that can photocatalytically degrade a variety of organic pollutants into non-toxic small molecular compounds, such as water, carbon dioxide, inorganic acids. Wait. After adding titanium dioxide to peroxide, the photon energy of titanium dioxide is above 3.1eV, so it needs to show catalytic activity in the ultraviolet band, but ultraviolet light with high photon energy has adverse effects on human soft tissue, and the safety factor is low. .

Therefore, in order to avoid the influence of ultraviolet light and improve the catalytic activity, the present invention performs surface modification on titanium dioxide, and doped titanium dioxide with non-metal ions (eg, nitrogen, carbon) to reduce the energy level of titanium dioxide and make the band gap of titanium dioxide. Narrowing, improving the photocatalytic activity and expanding the spectral range to the visible light region to achieve a catalytic effect on peroxides, this method can effectively reduce the concentration of peroxides, and use a moderate wavelength 450±10nm blue laser The light source or 405±5nm purple laser light source can not only achieve a certain brightness, but also meet the energy required for the photocatalytic reaction.

The advantages of the present invention are:

1. The concentration of peroxide in the tooth whitening gel of the present invention is relatively low, which avoids a series of oral problems such as the stimulation and damage to oral soft tissues and damage to the enamel surface due to the use of high-concentration peroxides in the current dental clinic. , has the characteristics of significant and safe teeth whitening effect.

2. The tooth whitening gel of the present invention can be prepared on-site during use, and can also be directly produced into a product with a certain shelf life that can be sold, including two parts of an independently packaged whitening agent and a catalytic care agent; The combined use of the catalytic nursing agent ensures that the patient feels less discomfort during use, and the user experience is comprehensively improved.

3. The catalyst care agent of the present invention contains an anti-caries agent and a desensitizing agent, which can effectively relieve a series of oral problems such as tooth sensitivity, is suitable for tooth whitening with endogenous staining and exogenous staining, and provides a safe and secure solution for the majority of beauty-loving people. , Effective technical services.

4. In the present invention, the raw materials for preparing the tooth whitening gel are readily available, the market supply is abundant, and the preparation process is relatively simple, suitable for industrial production, and the training cost of production personnel is low.

5. When using the invented tooth whitening gel to whiten teeth, it is easy to use. The blue laser light source of 450±10nm or the purple laser light source of wavelength 405±5nm is used to light the teeth, and the temperature and brightness are moderate, which can reduce or avoid the physical therapy process of patients. The discomfort caused by the 450±10nm blue laser light source is used, and the whitening effect is more significant.

Description of drawings

Fig. 1 is the effect diagram of using 450nm blue laser light source irradiation to carry out teeth whitening in the present invention;

Fig. 2 is the effect diagram of using 405nm violet laser light source to irradiate teeth whitening in the present invention;

Among them, in Figure 1 and Figure 2, H represents hydrogen peroxide, T represents nitrogen-doped titanium dioxide;

Figure 3 shows the surface morphology of normal tooth enamel under scanning electron microscope;

Fig. 4 is the surface morphology of tooth enamel after using tooth whitening gel blue laser whitening of the present invention under scanning electron microscope;

Fig. 5 is the tooth enamel surface morphology after using the tooth whitening gel violet laser whitening of the present invention under the scanning electron microscope;

Figure 6 shows the surface morphology of tooth enamel after whitening with the existing Opalescence whitening gel product under the scanning electron microscope;

Figure 7 shows the surface morphology of tooth enamel after whitening using the existing cold light under the scanning electron microscope.

Detailed ways

The content of the present invention is described in further detail below in conjunction with the accompanying drawings and specific embodiments:

Example 1

Prepare individually packaged whiteners and catalytic conditioners in tooth whitening gels according to the following formula:

Among them, the whitening agent contains 60 parts of hydrogen peroxide, 10 parts of nitrogen-doped titanium dioxide, 150 parts of disodium EDTA, 250 parts of glycerin, 5 parts of carbomer, 15 parts of sodium carboxymethyl cellulose, 510 parts of carbomer portion of purified water.

Its preparation method is as follows:

Step 1) fully dissolving peroxide and nitrogen-doped titanium dioxide in purified water to obtain a solution;

Step 2) Slowly add the stabilizer, the moisturizing agent and the binder into the solution, stir evenly, and let stand for 1 to 2 minutes to obtain a whitening agent.

The catalytic conditioner contains 15 parts carbomer, 20 parts sodium carboxymethyl cellulose, 330 parts glycerin, 30 parts disodium EDTA, 10 parts menthol, 75 parts sodium fluoride, 10 parts sodium phenyl potassium, 40 parts sodium citrate, 470 parts purified water.

Its preparation method is as follows:

S1) dissolving preservatives, stabilizers, anti-caries desensitizers, and pH regulators in purified water, and mixing them evenly to obtain a solution;

S2) the corrective is added to the moisturizing agent, after it is fully dissolved, it is added to the S1) solution;

S3) Add the adhesive to the solution obtained in S2), stir evenly, and let stand for 1 to 2 minutes to obtain a catalytic care agent.

Embodiment 2

Prepare individually packaged whiteners and catalytic conditioners in tooth whitening gels according to the following formula:

Among them, the whitening agent contains 90 parts of hydrogen peroxide, 0.5 parts of carbon-doped titanium dioxide, 140 parts of disodium EDTA, 200 parts of polyethylene glycol, 4 parts of carbomer, and 20 parts of sodium carboxymethyl cellulose. , 540 parts of purified water.

Catalytic Conditioner contains 10 parts Carbomer, 25 parts Sodium Carboxymethyl Cellulose, 350 parts Polyethylene Glycol, 43 parts Disodium EDTA, 10 parts Menthol, 65 parts Sodium Fluoride and Strontium Chloride , 12 parts sodium benzoate, 35 parts sodium citrate, 450 parts purified water.

The preparation methods of the whitening agent and the catalytic care agent are the same as those in the first embodiment.

Embodiment 3

Prepare individually packaged whiteners and catalytic conditioners in tooth whitening gels according to the following formula:

Among them, the whitening agent contains 40 parts of urea peroxide, 0.8 parts of nitrogen-doped titanium dioxide, 150 parts of disodium EDTA, 250 parts of glycerin, 5 parts of poloxamer, 10 parts of sodium carboxymethyl cellulose, 530 parts purified water.

The Catalytic Conditioner contains a combination of 12 parts Carbomer, 20 parts Sodium Carboxymethyl Cellulose, 330 parts Glycerin, 30 parts Disodium EDTA, 10 parts Menthol, 70 parts Sodium Fluoride and Potassium Nitrate, 10 parts methylparaben, 30 parts sodium citrate, 488 parts purified water.

The preparation methods of the whitening agent and the catalytic care agent are the same as those in Example 1.

Embodiment 4

Prepare individually packaged whiteners and catalytic conditioners in tooth whitening gels according to the following formula:

Among them, the whitening agent contains 60 parts of urea peroxide, 2 parts of carbon-doped titanium dioxide, 120 parts of sodium hydrogen phosphate, 250 parts of propylene glycol, 5 parts of carbomer, 15 parts of sodium carboxymethyl cellulose, and 500 parts of purified water.

Catalytic Conditioner contains 10 parts carbomer, 20 parts sodium carboxymethyl cellulose, 330 parts propylene glycol, 30 parts sodium hydrogen phosphate, 10 parts menthol, 70 parts strontium chloride, 10 parts sodium benzoate, 30 parts citric acid Sodium, 500 parts purified water.

The preparation methods of the whitening agent and the catalytic care agent are the same as those in Example 1.

Embodiment 5

Prepare tooth whitening gel according to the following formula:

30 parts hydrogen peroxide, 1 part carbon-doped titanium dioxide, 5 parts poloxamers, 10 parts sodium carboxymethylcellulose, 500 parts purified water

Teeth whitening gel prepared according to this formula has a short shelf life and is only suitable for use in on-site configuration.

Its preparation method is as follows:

Step 1) fully dissolving the titanium dioxide doped with peroxide and non-metal ions in purified water to obtain a solution;

Step 2) Slowly adding the adhesive to the solution, stirring evenly, and letting it stand for 1 to 2 minutes to obtain a tooth whitening gel containing only a whitening agent.

Embodiment 6

Prepare tooth whitening gel according to the following formula:

60 parts urea peroxide, 0.9 parts nitrogen-doped titanium dioxide, 15 parts carboxymethyl cellulose, 480 parts purified water;

The preparation method is the same as that of Example 5.

Embodiment 7

Prepare Teeth Whitening Gel according to the following recipe

50 parts hydrogen peroxide, 2 parts nitrogen-doped titanium dioxide, 10 parts sodium carboxymethyl cellulose, 3 parts carbomer mix, 510 parts purified water

The preparation method is the same as that of Example 5.

The using method of the tooth whitening gel of above-mentioned embodiment, comprises the following steps:

Step 1: Apply the whitening agent on the surface of the patient's teeth, or mix the whitening agent and the catalytic nursing agent in a weight ratio of 1:1 to 1.5, and then apply it to the surface of the patient's teeth to form a coating layer with a thickness of 1 mm to 2 mm;

In step 2, use a blue laser light source with a wavelength of 450±10nm or a purple laser light source with a wavelength of 405±5nm to irradiate the patient's teeth for 10 to 30 minutes;

Step 3: Remove the coating layer on the surface of the patient's teeth, and then the organic pigment on the surface of the teeth can be removed to achieve the effect of whitening teeth.

The technical parameters of the laser light source used are as follows:

Laser wavelength: 450nm±10nm, 405±5nm;

Laser power: 0～10W adjustable;

Laser output mode: continuous or pulse;

Pulse width: adjustable from 10 to 500ms;

Frequency: adjustable from 1 to 100Hz;

Duty cycle: adjustable from 10% to 100%;

Human-machine interface control: touch screen;

Mechanical control system: dental robotic arm.

According to the above method, the whitening effect of using the tooth whitening gel of the present invention under the irradiation of a blue laser light source with a wavelength of 450 ± 10 nm and a purple laser light source with a wavelength of 405 ± 5 nm is shown in Figure 1 and Figure 2 respectively:

1. It can be seen from Figure 1 and Figure 2 that with the increase of irradiation time, the change value of tooth color becomes larger and larger (the larger the value of tooth change, the whiter the teeth), that is to say, the longer the irradiation time, The whitening effect is better; and the whitening effect of adding doped nitrogen dioxide to hydrogen peroxide is better than that of only hydrogen peroxide;

2. Comparing Figure 1 and Figure 2, the same active ingredients can be seen from the tooth color change value (containing 6% hydrogen peroxide + 0.1% nitrogen-doped titanium dioxide; containing 3.5% hydrogen peroxide + 0.1% nitrogen-doped titanium dioxide) The whitening effect of irradiating teeth with a blue laser light source with a wavelength of 450±10nm is better than that of a purple laser light source with a wavelength of 405±5nm. The catalytic activity of doped titanium dioxide is better;

3. As shown in Figure 1, under the irradiation of a blue laser light source with a good effect of 450±10nm, the whitening gel containing 6% hydrogen peroxide has a better effect than the whitening gel containing 3.5% hydrogen peroxide.

In conjunction with existing tooth whitening gel and whitening method, the effect of tooth whitening gel of the present invention is evaluated from the following two angles:

(1) Evaluation of the effect of whitening degree

Utilize the tooth whitening effect standard colorimetric system (CIE L*a*b system) to test the whitening effect of Opaloid whitening gel, whitening gel of the present invention and household whitening gel, and the test results are shown in the following table:

Conclusion: From the value of ΔE, it can be concluded that the teeth whitening gel of the present invention has a better whitening effect.

(2) Evaluation of the effect of tooth damage

Observation of enamel after teeth whitening with different gels using a scanning electron microscope (×5000):

Figure 3 shows the surface morphology of normal tooth enamel under the scanning electron microscope. It can be observed that the normal tooth enamel surface is smooth and relatively flat;

Fig. 4 is the tooth enamel surface morphology after using the tooth whitening gel blue laser whitening of the present invention under the scanning electron microscope, it can be observed that after the blue laser whitening, the surface roughness of the tooth enamel increases, and there are shallow depressions formed locally;

Fig. 5 is the surface morphology of tooth enamel after whitening using the tooth whitening gel of the present invention with the violet laser under the scanning electron microscope. It can be observed that after the violet laser whitening, the increase in the surface roughness of the enamel is more obvious than that of the blue laser, and there are also shallow depressions formed locally. ;

Figure 6 shows the surface morphology of tooth enamel after whitening with the existing Opalescence whitening gel product under the scanning electron microscope. It can be observed that the surface roughness of the tooth enamel increases more than the laser group (Figure 4 and Figure 5) after whitening. Obviously, local deep depressions are formed;

Figure 7 shows the surface morphology of the tooth enamel after using the existing cold light whitening under the scanning electron microscope. It can be observed that the enamel surface changes like an etching after the cold light whitening and bleaching.

It can be concluded from this that the use of whitening gel to whiten teeth will cause large or small damage to the enamel on the tooth surface and increase the roughness of the tooth enamel surface; The whitening gel has minimal damage under blue laser irradiation.

The above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited to this. Any person skilled in the art can easily think of various equivalents within the technical scope disclosed by the present invention. Modifications or substitutions should be included within the protection scope of the present invention.

Claims (10)

1. a kind of tooth whitening gel, it is characterised in that: including whitening agent；

The whitening agent includes 30 parts~100 parts peroxide, 0.5 part~10 parts nonmetallic ion-doped titanium dioxide, 15 Part~20 parts of adhesives and 450 parts~540 parts purified waters.

2. tooth whitening gel according to claim 1, it is characterised in that: the peroxide is hydrogen peroxide, peroxide Change urea, one of which or multiple combinations in perborate；

The nonmetallic ion-doped titanium dioxide be the titanium dioxide of N doping, carbon doping titanium dioxide in wherein one Kind or two kinds of combination.

3. tooth whitening gel according to claim 2, it is characterised in that: the whitening agent further includes 100 parts~150 parts Stabilizer and 160 parts~250 parts moisturizer.

4. tooth whitening gel according to claim 2 or 3, it is characterised in that: further include catalysis care agent；

The catalysis care agent includes 32 parts~40 parts adhesives, 330 parts~350 parts moisturizer, 20 parts~50 parts stabilizers, 5 Part~10 parts of corrigents, 65 parts~75 parts preventing decayed tooth desensitizers, 9 parts~14 portions preservatives, 35 parts~45 parts pH adjusting agents, 450 parts ~500 parts of purified waters；

The whitening agent and catalysis care agent are independent packaging.

5. tooth whitening gel according to claim 4, it is characterised in that:

The stabilizer is disodium ethylene diamine tetraacetate, dibastic sodium phosphate, one of or a variety of combination in citric acid；

The moisturizer is glycerol, polyethylene glycol, one of or a variety of combination in propylene glycol；

Described adhesive is one of or a variety of group in sodium carboxymethylcellulose, carbomer, pool network sand nurse or gelatin It closes；

The corrigent is menthol；

The preventing decayed tooth desensitizer is strontium chloride, fluoride, one of or a variety of combination in potassium nitrate；

The preservative is sodium benzoate, methylparaben, one of or a variety of combination in ethylparaben；

The pH adjusting agent is sodium citrate, the one of which of potassium citrate or two kinds of combination.

6. tooth whitening gel according to claim 5, it is characterised in that:

The whitening agent includes the titanium dioxide of 60 parts of hydrogen peroxide and 1 part of N doping.

7. a kind of preparation method of tooth whitening gel, it is characterised in that: the preparation method including whitening agent；

The whitening agent the preparation method is as follows:

Step 1) sufficiently dissolves 30 parts~100 parts peroxide and 0.5 part~10 parts nonmetallic ion-doped titanium dioxide In 450 parts~540 parts purified waters, solution is obtained；

15 parts~20 parts adhesives are slowly added into the solution by step 2), are stirred evenly, and are stood 1min~2min, are obtained Whitening agent.

8. the preparation method of tooth whitening gel according to claim 7, it is characterised in that: further include the system for being catalyzed care agent Preparation Method；

It is described catalysis care agent the preparation method is as follows:

S1) by 9 parts~14 portions preservatives, 20 parts~50 parts stabilizers, 65 parts~75 parts preventing decayed tooth desensitizers, 35 parts~45 parts pH tune Section agent is dissolved in 450 parts~500 parts purified waters, is uniformly mixed, is obtained solution；

S2) 5 parts~10 parts corrigents are added in 330 parts~350 parts moisturizer, after completely dissolution to it, are added to S1) institute It states in solution；

S3 32 parts~40 parts adhesives) are added to S2) in obtained solution, stirs evenly, stand 1min~2min, urged Change care agent.

9. preparation method according to claim 7 or 8, which is characterized in that step 2) comprises the concrete steps that: by 100 parts~ 150 parts of stabilizers, 160 parts~250 parts moisturizer and 15 parts~20 parts adhesives are slowly added into the solution, stirring Uniformly, 1min~2min is stood, whitening agent is obtained.

10. a kind of application method of tooth whitening gel, it is characterised in that:

Whitening agent is applied to patient teeth surface by step 1, or by whitening agent and is catalyzed care agent according to the weight of 1:1~1.5 Amount ratio is applied to patient teeth surface after mixing, forms the coat with a thickness of 1mm~2mm；

The purple laser light source that the blue laser light source or wavelength that step 2 is 450 ± 10nm using wavelength are 405 ± 5nm, which irradiates, suffers from Person's tooth 10min~30min；

The coat on step 3 removing patient teeth surface.