CN109988705A - A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device - Google Patents
A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device Download PDFInfo
- Publication number
- CN109988705A CN109988705A CN201910376197.1A CN201910376197A CN109988705A CN 109988705 A CN109988705 A CN 109988705A CN 201910376197 A CN201910376197 A CN 201910376197A CN 109988705 A CN109988705 A CN 109988705A
- Authority
- CN
- China
- Prior art keywords
- micromanipulation
- test
- preparing device
- circular drop
- ware
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000011159 matrix material Substances 0.000 title claims abstract description 36
- 239000007788 liquid Substances 0.000 claims abstract description 49
- 238000012546 transfer Methods 0.000 claims abstract description 29
- 230000005540 biological transmission Effects 0.000 claims abstract description 27
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 230000003014 reinforcing effect Effects 0.000 claims description 3
- 238000002474 experimental method Methods 0.000 abstract description 8
- 239000003792 electrolyte Substances 0.000 abstract description 5
- 230000003204 osmotic effect Effects 0.000 abstract description 5
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 239000012141 concentrate Substances 0.000 abstract description 2
- 230000000694 effects Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 6
- 230000013011 mating Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 238000000926 separation method Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/40—Manifolds; Distribution pieces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing devices, including pressure transmission disk, filter core and liquid transfer gun head；The pressure transmission disk is flat cuboid structure；The beneficial effects of the present invention are, first, matrix preparing device of the invention is connected with single channel pipettor, the uninteresting circular drop preparation work of complexity daily in each laboratory IVF easily can be become more convenient, greatly operator is repeated to free in mechanical operation from these, concentrates one's energy to carry out more importantly matters；Secondly, matrix preparing device of the invention is that synchronization disposably prepares one group of multiple circular drop in the same operation ware or culture dish, the Water-Electrolyte osmotic pressure inside same group of circular drop in the same operation ware or culture dish keeps height consistent, the accuracy and repeatability that ensure that IVF experiment, for expeditiously guaranteeing that the effect of IVF experimental result is great.
Description
Technical field
The present invention relates to Med Biol technical field more particularly to a kind of dedicated multi-pass of test-tube baby's micromanipulation ware
Road circular drop matrix preparing device.
Background technique
Operation ware in tube-test baby techniques or the circular drop preparation manipulation in culture dish are wherein most basic, most normal
One of rule, the maximum operating procedure of workload, current operation mainly pass through the single channel manual pipettor (rifle) of 200ul
Mating liquid relief plastics pipette tips carry out various types of related liquids and pipette, prepare various operations, culture drop, operation therein
Or culture circular drop usually needs to prepare 8-10 because dosage is bigger in each conventional operation or culture dish,
And in the bigger laboratory of workload, this operation ware or culture dish quantity for needing to use daily are very huge, this
The workload that sample prepares these circular drops is even more surprising.
Currently, it is limited to prior art strength and mating pipettor and liquid transfer gun head condition, it is entirely artificial each
Single drop of testing liquid operation, manual method puts upper 8-10 circular drop one by one on an operation ware or culture dish, is arranged into 2
Rectangular array is arranged, with reaching the mesh for preparing more droplet manipulation wares or culture dish, but this method is time-consuming and laborious, and there is elder generation in the time
Afterwards, cause Water-Electrolyte osmotic pressure internal between the drop of preparation etc. not consistent, this also causes the IVF experiment in downstream
Certain puzzlement affects the accuracy and repeatability of IVF integral experiment, how to avoid the appearance for preventing such problem, convenient
Circular drop operation ware or the preparation of culture dish high throughput in the IVF experiment under big throughput requirements are quickly and efficiently completed to rate, is one
A urgent problem.
Summary of the invention
1. the technical issues that need to address
The technical problem to be solved in the invention is, it is round to provide a kind of test-tube baby's micromanipulation ware special multichannel
Drop matrix preparing device solves to need to prepare in IVF (external reproduction) scientific research clinic production work to carry 8-10 matrix arrangement
The problem of a large amount of operation wares or culture dish of circular drop, under the conditions of existing, operator must be moved manually by single track
Liquid device cooperates single liquid transfer gun head, one by one 4 or 5 20uL of two rows or so on careful place on each operation ware or culture dish
The circular drop of volume range size, then cooperate remaining operation, corresponding operation ware or culture dish are prepared, this method is time-consuming
Arduously, in the case where high throughput requires, physical strength and endurance for operator are a serious tests, and these circular drop systems
The time got ready has Water-Electrolyte osmotic pressure internal between the drop for successively leading to prepare etc. not consistent, this is also right
The IVF experiment in downstream causes certain puzzlement, affects the accuracy and repeatability of IVF integral experiment, we devise one
The special IVF special multichannel circular drop matrix preparing device of money cooperates various volume single tracks conventional in the laboratory IVF manual
Pipettor can disposably synchronize satisfactory 8-10 round operation or culture drop in the preparation laboratory IVF, significantly
It facilitates under high-throughput require, conveniently and efficiently prepares IVF operation ware or culture dish, ensure that same operation ware or culture dish
The high consistency of Water-Electrolyte osmotic pressure inside one group of interior circular drop, ensure that the stringent of all kinds of IVF experimental results
Accuracy and high duplication, expeditiously complete under big throughput requirements IVF experiment in circular drop matrix manipulation ware preparation or
The problem of prepared by culture dish high throughput, can more match with a variety of automation liquid relief operating systems.
2. technical solution
To achieve the goals above, the technical scheme is that a kind of test-tube baby's micromanipulation ware special multichannel
Circular drop matrix preparing device, including pressure transmission disk, filter core and liquid transfer gun head；The pressure transmission disk is flat cuboid knot
Structure, the pressure transmission disk end face center upwardly extend to form pipettor connector, and the pipettor connector is offered along axis
Air inlet；Pressure transmission face of trying to get to the heart of a matter along axis interval extends to form several liquid transfer gun heads, several liquid transfer gun heads
In along the rectangular of the pressure transmission disk length-width direction, and respectively in length direction and wide direction arranged at equal intervals；The pressure
Cavity is offered in transmission plate, and the cavity is connected to the air inlet and several liquid transfer gun heads；The filter core is mounted on institute
It states in cavity.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein the shifting
Liquid device connector is up big and down small hollow round table structure, outside diameter 7mm, end diameter 5.5mm, the pipettor connector
Wall thickness is 1mm.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein the shifting
The radially inwardly extending formation reinforcing ring in liquid device connector internal perisporium top.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein the shifting
Frosting is provided at the top of liquid device connector periphery wall, and the frosting length is 4mm.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein the pressure
Power transmission plate length is 20mm, width 12mm, with a thickness of 1mm；The cavity is cuboid structure, length 18mm, width
For 10mm, with a thickness of 0.5mm.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein Ruo Gansuo
State liquid transfer gun head composition four rows, two column matrix.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein Tong Hanghuo
The center of the two neighboring liquid transfer gun head of same column is away from for 4mm.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein Ruo Gansuo
Stating the minimum range between liquid transfer gun head and pressure transmission disk sideline is 4mm.
A kind of above-mentioned test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, wherein the shifting
Liquid pipette tips are made of top cylinder and lower part horn mouth；The outside diameter of cylinder is 4mm, wall thickness 0.5mm, length 9mm；It is described
Horn mouth bottom outer diameter is 0.8mm, wall thickness 0.2mm, length 1mm.
3. beneficial effect
In conclusion the beneficial effects of the present invention are:
(1) matrix preparing device of the invention is connected with single channel pipettor, can be easily Sino-Japan by each laboratory IVF
Often complicated uninteresting circular drop preparation work becomes more convenient, and operator is greatly repeated machinery from these
It is freed in operation, concentrates one's energy to carry out more importantly other business；
(2) matrix preparing device of the invention is that synchronization disposably prepares one group in the same operation ware or culture dish
Multiple circular drops, it is same operation ware or culture dish in same group of circular drop inside Water-Electrolyte osmotic pressure keep height
Unanimously, the accuracy and repeatability that ensure that IVF experiment, for expeditiously guaranteeing that the effect of IVF experimental result is great.
Detailed description of the invention
Fig. 1 is that a kind of structure of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device of the present invention is shown
It is intended to.
Fig. 2 is a kind of section view of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device of the present invention
Figure.
Specific embodiment
The following is further explained with reference to the attached drawings the embodiment of the present invention.
It please refers to shown in attached drawing 1 and attached drawing 2, a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix system
Standby device, including pressure transmission disk 1, filter core 4 and liquid transfer gun head 2；The pressure transmission disk 1 is flat cuboid structure, the pressure
1 end face center of transmission plate upwardly extends to form pipettor connector 3, and the pipettor connector 3 offers air inlet along axis
301；1 bottom surface of pressure transmission disk extends to form several liquid transfer gun heads 2, several liquid transfer gun heads 2 along axis interval
In along the rectangular of 1 length-width direction of pressure transmission disk, and respectively in length direction and wide direction arranged at equal intervals；The pressure
Cavity 101 is offered in transmission plate 1, and the cavity 101 is connected to the air inlet 301 and several liquid transfer gun heads 2；The filter
Core 4 is mounted in the cavity 101.
3 outer profile of pipettor connector is up big and down small hollow round table structure, outside diameter 7mm, end diameter
For 5.5mm, the pipettor connector wall thickness is 1mm, and the pipettor connector 3 connect with the manual single track pipettor of 200uL, is used for
Transmit the liquid relief air pressure that pipettor generates.
The radially inwardly extending formation reinforcing ring 303 in the 3 internal perisporium top of pipettor connector can effectively increase described
Connection frictional force between pipettor connector 3 and manual single track pipettor prevents the terminal pad 1 during pipetting
It slides, liquid relief is caused to fail.
Frosting 302 is provided at the top of 3 periphery wall of pipettor connector, and 302 length of the frosting is 4mm, side
When just under special circumstances, as needed to tighten by hand or remove this special pipette tips, increases hand contact surface, facilitate these special
In the case of direct manual operation, make marks when also facilitating operation.
1 length of pressure transmission disk is 20mm, width 12mm, with a thickness of 1mm；The cavity 102 is cuboid knot
Structure, length 18mm, width 10mm, with a thickness of 0.5mm.
Several liquid transfer gun heads 2 form four rows, two column matrix, and several liquid transfer gun heads 2 and 1 side of pressure transmission disk
Minimum range between line is 4mm, and the center of colleague or the two neighboring liquid transfer gun head 2 of same column guarantees pressure biography away from being 4mm
It is defeated directly in time uniformly, can be by liquid relief pressure swimmingly in the more of single track pipettor and mating connection in liquid relief liquid separation operation
It is transmitted mutually between a liquid transfer gun head 2, and pressure when pipetting inside each 3 end of liquid transfer gun head keeps stringent
It is synchronous, it is ensured that pipetting volume is consistent, reproducible.
The liquid transfer gun head 2 is made of top cylinder 201 and lower part horn mouth 202；201 outer diameter of cylinder be 4mm,
Wall thickness is 0.5mm, length 9mm；The 202 bottom outer diameter of horn mouth is 0.8mm, wall thickness 0.2mm, length 1mm.
Application method: the pipettor connector is connect with the Eppendorf single track pipettor of 200uL specification, then, directly
Connect and the total pipetting volume of 120uL carried out by the liquid transfer gun head 2 that extends out of pressure transmission disk 1,8 circular drop matrixes of synchronous preparation into
Row example at the same time can be according to concrete application difference, it is possible to provide be suitble to such multi-pass of different range ability liquid separation requirements
Liquid transfer gun head 2 described in road is connected with single channel pipettor.
The above description is only a preferred embodiment of the present invention, is not intended to limit the scope of the invention, all utilizations
Equivalent structure transformation made by present specification, directly or indirectly with the technology neck for being attached to other Related products
Domain is included within the scope of the present invention.
Claims (9)
1. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device, it is characterised in that: including pressure
Transmission plate (1), filter core (4) and liquid transfer gun head (2)；The pressure transmission disk (1) is flat cuboid structure, the pressure transmission disk
(1) end face center upwardly extends to be formed pipettor connector (3), and the pipettor connector (3) offers air inlet along axis
(301)；Pressure transmission disk (1) bottom surface extends to form several liquid transfer gun heads (2), several liquid reliefs along axis interval
Pipette tips (2) are in and to arrange at equal intervals in length direction and wide direction respectively along the rectangular of pressure transmission disk (1) length-width direction
Column；It offers cavity (101) in the pressure transmission disk (1), and the cavity (101) and the air inlet (301) and several
Liquid transfer gun head (2) connection；The filter core (4) is mounted in the cavity (101).
2. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 1,
It is characterized by: liquid relief connector (3) outer profile is up big and down small hollow round table structure, outside diameter 7mm, small end are straight
Diameter is 5.5mm, and the liquid relief connector wall thickness is 1mm.
3. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 2,
It is characterized by: the radially inwardly extending formation reinforcing ring (303) in liquid relief connector (3) internal perisporium top.
4. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 2,
It is characterized by: being provided with frosting (302) at the top of liquid relief connector (3) periphery wall, and the frosting (302) length is
4mm。
5. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 1,
It is characterized by: pressure transmission disk (1) length is 20mm, width 12mm, with a thickness of 1mm；The cavity (102) is square
Physique structure, length 18mm, width 10mm, with a thickness of 0.5mm.
6. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 1,
It is characterized by: several liquid transfer gun heads (2) form four rows, two column matrix.
7. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 6,
It is characterized by: the distance of center circle of colleague or the two neighboring liquid transfer gun head (2) of same column is 4mm.
8. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 8,
It is characterized by: the minimum range between several liquid transfer gun heads (2) and pressure transmission disk (1) sideline is 4mm.
9. a kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device according to claim 1,
It is characterized by: the liquid transfer gun head (2) is made of top cylinder (201) and lower part horn mouth (202)；The cylinder (201)
Outer diameter is 4mm, wall thickness 0.5mm, length 9mm；Horn mouth (202) bottom outer diameter is 0.8mm, wall thickness 0.2mm, length
Degree is 1mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910376197.1A CN109988705A (en) | 2019-05-07 | 2019-05-07 | A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910376197.1A CN109988705A (en) | 2019-05-07 | 2019-05-07 | A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109988705A true CN109988705A (en) | 2019-07-09 |
Family
ID=67136090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910376197.1A Pending CN109988705A (en) | 2019-05-07 | 2019-05-07 | A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109988705A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113278525A (en) * | 2021-05-24 | 2021-08-20 | 山东优检生物技术有限公司 | Stem cell ball or tumor ball culture device and culture method |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19826065A1 (en) * | 1998-06-12 | 1999-12-16 | Eppendorf Geraetebau Netheler | Multiple dispensing head, laboratory syringe pipettes, with rapid release, magnetic coupling between head and actuator |
| US20070048188A1 (en) * | 2003-09-26 | 2007-03-01 | Bigus Hans J | Multi-channel pipette device |
| US20120121483A1 (en) * | 2010-11-15 | 2012-05-17 | Thermo Fisher Scientific Oy | Multichannel pipette |
| CN202983711U (en) * | 2012-11-21 | 2013-06-12 | 福建和泉生物科技有限公司 | Multi-channel micropipettor |
| CN203790958U (en) * | 2014-02-21 | 2014-08-27 | 南京先进激光技术研究院 | Automatic multi-channel pipettor of real-time detection of suction head |
| CN204911556U (en) * | 2015-09-22 | 2015-12-30 | 浙江尚泰生物技术有限公司 | Multi -channel pipettor |
| CN208356809U (en) * | 2018-05-17 | 2019-01-11 | 上海欧颖实验设备有限公司 | Multi-channel liquid transfer device |
| CN109499637A (en) * | 2019-01-27 | 2019-03-22 | 刘晓 | A kind of bent angle liquid relief plastics pipette tips |
| CN211367553U (en) * | 2019-05-07 | 2020-08-28 | 刘晓 | Multi-channel circular liquid drop matrix preparation device special for test tube baby micro-operation vessel |
-
2019
- 2019-05-07 CN CN201910376197.1A patent/CN109988705A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19826065A1 (en) * | 1998-06-12 | 1999-12-16 | Eppendorf Geraetebau Netheler | Multiple dispensing head, laboratory syringe pipettes, with rapid release, magnetic coupling between head and actuator |
| US20070048188A1 (en) * | 2003-09-26 | 2007-03-01 | Bigus Hans J | Multi-channel pipette device |
| US20120121483A1 (en) * | 2010-11-15 | 2012-05-17 | Thermo Fisher Scientific Oy | Multichannel pipette |
| CN202983711U (en) * | 2012-11-21 | 2013-06-12 | 福建和泉生物科技有限公司 | Multi-channel micropipettor |
| CN203790958U (en) * | 2014-02-21 | 2014-08-27 | 南京先进激光技术研究院 | Automatic multi-channel pipettor of real-time detection of suction head |
| CN204911556U (en) * | 2015-09-22 | 2015-12-30 | 浙江尚泰生物技术有限公司 | Multi -channel pipettor |
| CN208356809U (en) * | 2018-05-17 | 2019-01-11 | 上海欧颖实验设备有限公司 | Multi-channel liquid transfer device |
| CN109499637A (en) * | 2019-01-27 | 2019-03-22 | 刘晓 | A kind of bent angle liquid relief plastics pipette tips |
| CN211367553U (en) * | 2019-05-07 | 2020-08-28 | 刘晓 | Multi-channel circular liquid drop matrix preparation device special for test tube baby micro-operation vessel |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113278525A (en) * | 2021-05-24 | 2021-08-20 | 山东优检生物技术有限公司 | Stem cell ball or tumor ball culture device and culture method |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109182092B (en) | A microfluidic chip for nucleic acid detection and its application | |
| CN103008039B (en) | Possesses the multiple liquid-transfering device moving liquid head moving liquid passage lining up certain general layout of band | |
| US8117925B2 (en) | Apparatus and method for using a tip collar on pipette tips providing structural rigidity | |
| EP3682969B1 (en) | Pipette tip adapter assembly | |
| CN107498038B (en) | Multi-cavity pressureless sintered graphite mold | |
| CN107008517A (en) | Micro-fluidic chip and its droplet generating means | |
| CN109988705A (en) | A kind of test-tube baby's micromanipulation ware special multichannel circular drop matrix preparing device | |
| JP2021520785A (en) | Microfluidic systems and methods for naked mammalian oocytes | |
| US20230201822A1 (en) | Pipette tip adapter | |
| WO2023236760A1 (en) | Printing apparatus matched with microfluidic chip and printing method | |
| CN211367553U (en) | Multi-channel circular liquid drop matrix preparation device special for test tube baby micro-operation vessel | |
| CN208583358U (en) | Elongated drop prepares liquid relief plastics pipette tips | |
| US20080101996A1 (en) | Multi-channel design for a liquid-handling pipette | |
| CN218435664U (en) | PCR amplification container consumable box | |
| CN209791572U (en) | Biological sample save set | |
| CN207927586U (en) | A kind of drosophila culture tube pipe lid and culture apparatus | |
| CN210419986U (en) | Multipurpose circular liquid drop matrix preparation adapter for mammal embryo operation culture | |
| CN105675775B (en) | A kind of quick on-line sampling of gas-chromatography, storage and sample introduction device and method | |
| US7387036B2 (en) | Vessel with retention features and method therefor | |
| US20170282188A1 (en) | Apparatus and method for using a tip collar on a single row of pipette tips | |
| CN213835320U (en) | Efficient microorganism plate dotting device | |
| CN110066731A (en) | Multipurpose mammal embryo operates culture and prepares adapter with circular drop matrix | |
| CN109603951A (en) | Pipe support | |
| CN222524500U (en) | A 48-well two-color PCR plate | |
| CN204417484U (en) | Built-up type PCR plate |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |