CN109971632A - The storing compartment of chip in a kind of gene sequencing - Google Patents
The storing compartment of chip in a kind of gene sequencing Download PDFInfo
- Publication number
- CN109971632A CN109971632A CN201910305706.1A CN201910305706A CN109971632A CN 109971632 A CN109971632 A CN 109971632A CN 201910305706 A CN201910305706 A CN 201910305706A CN 109971632 A CN109971632 A CN 109971632A
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- chip
- sliding block
- plate
- main body
- probe
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
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- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of storing compartment of chip in gene sequencing, including main body frame, the both ends of the main body frame are connected with support foot；Also there are several drawing and pulling type experiment bins in array distribution on main body frame, the drawing and pulling type experiment bin includes main cabin body, chip bearing plate and sliding block loading plate；Also there are several chip placing grooves in array distribution on the upper surface of chip bearing plate；Several through slots to match with chip placing groove are additionally provided on sliding block loading plate, probe installation sliding block is respectively arranged in each through slot, probe is housed on the lower surface of the probe installation sliding block, the two sides of the main cabin body are connected with overturning pressing plate, when overturning pressing plate withdrawal, the lower surface for overturning pressing plate is pressed on the upper surface of probe installation sliding block.The present apparatus is simple and practical, and the generation of mutual pollution condition between chip can be effectively prevented.
Description
Technical field
The present invention relates to a kind of storing compartments of chip in gene sequencing.
Background technique
The prototype of genetic chip (genechip) (also known as DNA chip, biochip) is that the mid-80 proposes.Gene
The sequencing principle of chip is sequencing by hybridization method, i.e., by carrying out nucleic acid sequence survey with the nucleic acid probe hybridization of one group of known array
Fixed method secures the probe of target nucleotide known to sequence in one piece of substrate surface.In terms of practical application, biochip
Technology can be widely applied to medical diagnosis on disease and treatment, drug screening, the good child-rearing of crops preferably, judicial expertise, food hygiene prison
It superintends and directs, environment measuring, national defence, many fields such as space flight.It will be human knowledge's origin of life, heredity, development and evolution, be people
Completely new approach is opened up in diagnosis, treatment and the prevention and treatment of class disease, is guide in the brand-new design and drug development of large biological molecule
The quick screening and pharmacogenomics research of compound provide technical platform.
Presently, there are genetic chip be that base membrane layer is set on slide, detection probe is set on base membrane layer, and in perseverance
A period of time is handled under the conditions of temperature.It needs for chip, probe to be placed in storing compartment when processing, but existing storing compartment is often not
Can guarantee will not mutually be in contact pollution between chip.
Summary of the invention
The purpose of the present invention is to solve the above the deficiencies in the prior art, a kind of storage of chip in gene sequencing is provided
Cabinet.
The storing compartment of chip in a kind of gene sequencing, including main body frame, the both ends of the main body frame are connected with support foot,
The upper surface of the support foot is equipped with deep gouge, and deep gouge is provided with adjustable plate, the top of the adjustable plate and the lower surface of main body frame
It is connected, the side of deep gouge is connected with housing pin, and the head of the housing pin is connected to the side of adjustable plate；On main body frame also
There are several drawing and pulling type experiment bins in array distribution, the drawing and pulling type experiment bin includes that main cabin body, chip bearing plate and sliding block are held
Support plate；The two sides of the main cabin body inner wall are equipped with sliding rail, and the side of chip bearing plate is equipped with the sliding slot to match with sliding rail, chip
Also there are several chip placing grooves in array distribution on the upper surface of loading plate；The top of the sliding rail is equipped with one group of locating piece,
The locating piece is evenly distributed on the four corners of main cabin body inner wall, and being surrounded by for sliding block loading plate is determined with what locating piece matched
Position notch is additionally provided with the through slot that several and chip placing groove match on sliding block loading plate, is respectively arranged with probe peace in each through slot
Sliding block is filled, probe is housed on the lower surface of the probe installation sliding block, the two sides of the main cabin body are connected with overturning pressing plate, when
When overturning pressing plate withdrawal, the lower surface for overturning pressing plate is pressed on the upper surface of probe installation sliding block.
Preferably, it is connected between the overturning pressing plate and main cabin body by hinge.
Preferably, multiplying 3 array distributions in 3 on the main body frame has 9 drawing and pulling type experiment bins.
Preferably, also multiplying 5 array distributions in 4 on the upper surface of the chip bearing plate has 20 chip placing grooves.
Preferably, postive stop baffle is additionally provided on the upper surface of probe installation sliding block.
The utility model has the advantages that
1, using the design of double-supporting foot, the height of main body frame can be freely adjusted, can be put in the bottom of main body frame
Other experiment equipments are set, so that the working region utilization rate of workbench in laboratory is improved, in order to put more experiments
Equipment.
2, it is in the multiple drawing and pulling type experiment bins of array distribution on main body frame, the sequencing need of multiple groups chip can be met simultaneously
It asks, and can effectively prevent and generate pollution between chip.
3, probe is mounted on probe installation sliding block, it, can be very easily using the design for being similar to type printing
Probe is replaced, and can be according to the quantity of chip, reasonable installation probe installs sliding block, to reduce unnecessary waste.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the storing compartment of chip in gene sequencing；
Fig. 2 is a kind of main view of the storing compartment of chip in gene sequencing；
Fig. 3 is a kind of explosive view of drawing and pulling type experiment bin in the storing compartment of chip in gene sequencing；
1. 42. chip bearing plate of main body frame 2. support foot, 3. housing screw, 4. drawing and pulling type experiment bin, 41. main cabin body, 421. core
43. sliding block loading plate of piece placing groove, 44. probe installs sliding block 45. and overturns pressing plate.
Specific embodiment
In order to deepen the understanding of the present invention, below in conjunction with embodiment and attached drawing, the invention will be further described, should
The examples are only for explaining the invention, is not intended to limit the scope of the present invention..
As shown in Figure 1-3, in a kind of gene sequencing chip storing compartment, including main body frame 1, the main body frame 1
Both ends are connected with support foot 2, and the upper surface of the support foot 2 is equipped with deep gouge, and deep gouge is provided with adjustable plate, the top of the adjustable plate with
The lower surface of main body frame is connected, and the side of deep gouge is connected with housing pin 3, and the head of the housing pin 3 is connected to adjustable plate
Side；Multiplying 3 array distributions in 3 on main body frame 1 has 9 drawing and pulling type experiment bins 4.
The drawing and pulling type experiment bin 4 includes main cabin body 41, chip bearing plate 42 and sliding block loading plate 43；The main cabin body 41
The two sides of inner wall are equipped with sliding rail, and the side of chip bearing plate is equipped with the sliding slot to match with sliding rail, the upper surface of chip bearing plate
On also multiply 5 array distributions in 4 and have 20 chip placing grooves 421；The top of the sliding rail is equipped with one group of locating piece, the positioning
Block is evenly distributed on the four corners of main cabin body inner wall, and sliding block loading plate 43 is surrounded by the locating notch to match with locating piece,
It is additionally provided with several through slots to match with chip placing groove 421 on sliding block loading plate 43, probe installation is respectively arranged in each through slot
Sliding block 44, the probe are installed and probe are housed on the lower surface of sliding block 44, are additionally provided on the upper surface of probe installation sliding block 44
Postive stop baffle, postive stop baffle fall to ground for preventing probe installation sliding block from sliding from through slot.
The two sides of the main cabin body 41 are connected with overturning pressing plate 45, pass through between the overturning pressing plate 45 and main cabin body 41
Hinge is connected.When overturning the withdrawal of pressing plate 45, the lower surface of overturning pressing plate 45 is pressed on the upper surface of probe installation sliding block 44.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (5)
1. the storing compartment of chip in a kind of gene sequencing, which is characterized in that including main body frame, the both ends of the main body frame are equal
It is connected with support foot, the upper surface of the support foot is equipped with deep gouge, and deep gouge is provided with adjustable plate, the top of the adjustable plate and main body frame
Lower surface be connected, the side of deep gouge is connected with housing pin, and the head of the housing pin is connected to the side of adjustable plate；Main body
Also there are several drawing and pulling type experiment bins in array distribution on frame, the drawing and pulling type experiment bin includes main cabin body, chip bearing plate
With sliding block loading plate；The two sides of the main cabin body inner wall are equipped with sliding rail, and the side of chip bearing plate is equipped with to match with sliding rail
Sliding slot also has several chip placing grooves in array distribution on the upper surface of chip bearing plate；The top of the sliding rail is equipped with one
Group locating piece, the locating piece are evenly distributed on the four corners of main cabin body inner wall, and sliding block loading plate being surrounded by and positioning
The locating notch that block matches, is additionally provided with the through slot that several and chip placing groove match on sliding block loading plate, in each through slot
Sliding block is installed equipped with probe, probe is housed on the lower surface of the probe installation sliding block, the two sides of the main cabin body are connected with
Pressing plate is overturn, when overturning pressing plate withdrawal, the lower surface for overturning pressing plate is pressed on the upper surface of probe installation sliding block.
2. the storing compartment of chip in a kind of gene sequencing according to claim 1, which is characterized in that the overturning pressing plate
It is connected between main cabin body by hinge.
3. the storing compartment of chip in a kind of gene sequencing according to claim 1, which is characterized in that the main body frame
Above multiplying 3 array distributions in 3 has 9 drawing and pulling type experiment bins.
4. the storing compartment of chip in a kind of gene sequencing according to claim 1, which is characterized in that the chip bearing
Also multiplying 5 array distributions in 4 on the upper surface of plate has 20 chip placing grooves.
5. the storing compartment of chip in a kind of gene sequencing according to claim 1, which is characterized in that the probe installation
Postive stop baffle is additionally provided on the upper surface of sliding block.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910305706.1A CN109971632B (en) | 2019-04-16 | 2019-04-16 | Storage cabinet for chips in gene sequencing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910305706.1A CN109971632B (en) | 2019-04-16 | 2019-04-16 | Storage cabinet for chips in gene sequencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109971632A true CN109971632A (en) | 2019-07-05 |
| CN109971632B CN109971632B (en) | 2022-08-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910305706.1A Active CN109971632B (en) | 2019-04-16 | 2019-04-16 | Storage cabinet for chips in gene sequencing |
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| Country | Link |
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| CN (1) | CN109971632B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2355716B (en) * | 1999-04-30 | 2004-06-23 | Agilent Technologies Inc | Polynucleotide array fabrication |
| CN205133582U (en) * | 2015-10-28 | 2016-04-06 | 北京泱深生物信息技术有限公司 | Genetic chip that layering set up |
| CN106754244A (en) * | 2016-12-05 | 2017-05-31 | 成都叮当自动化设备有限公司 | A kind of genetic chip case |
| CN207933428U (en) * | 2018-02-01 | 2018-10-02 | 天津威高分子诊断科技有限公司 | A kind of genetic chip of layering setting |
-
2019
- 2019-04-16 CN CN201910305706.1A patent/CN109971632B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2355716B (en) * | 1999-04-30 | 2004-06-23 | Agilent Technologies Inc | Polynucleotide array fabrication |
| CN205133582U (en) * | 2015-10-28 | 2016-04-06 | 北京泱深生物信息技术有限公司 | Genetic chip that layering set up |
| CN106754244A (en) * | 2016-12-05 | 2017-05-31 | 成都叮当自动化设备有限公司 | A kind of genetic chip case |
| CN207933428U (en) * | 2018-02-01 | 2018-10-02 | 天津威高分子诊断科技有限公司 | A kind of genetic chip of layering setting |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109971632B (en) | 2022-08-23 |
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