CN109964958A - A kind of microbicide compositions - Google Patents
A kind of microbicide compositions Download PDFInfo
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- CN109964958A CN109964958A CN201910193815.9A CN201910193815A CN109964958A CN 109964958 A CN109964958 A CN 109964958A CN 201910193815 A CN201910193815 A CN 201910193815A CN 109964958 A CN109964958 A CN 109964958A
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- CN
- China
- Prior art keywords
- composition
- activator protein
- moroxydine hydrochloride
- toverticilliumdahliaactivitie activitie
- relative activator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 229940044654 phenolsulfonic acid Drugs 0.000 description 1
- LGRFSURHDFAFJT-UHFFFAOYSA-N phthalic anhydride Chemical compound C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 229940088417 precipitated calcium carbonate Drugs 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 239000011265 semifinished product Substances 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides a kind of microbicide compositions, the composition includes two kinds of effective component toVerticilliumdahliaActivitie Activitie S of Relative activator proteins and Moroxydine Hydrochloride, and the weight ratio between two components is 1:10~160.The present invention also provides the Preparation method and uses of the composition.Test result shows that above-mentioned bactericidal composition synergy provided by the invention is obvious, it is often more important that amount of application is reduced, and use cost reduces.The bactericidal composition can effectively prevent certain specific bacteriums or the fungal disease of crop.By compounding the fungicide of different role mechanism and the mode of action, there is good effect for expand fungicidal spectrum and delay germ resistance and improve control efficiency etc..
Description
Technical field
The invention belongs to agriculture plant protection fields, more particularly to a kind of with the bactericidal composition for improving performance, tool
Say to body it is to be related to a kind of bactericidal composition comprising toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride.
Background technique
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein is a kind of novel protein screen, separate from Alternariaspp, being purified into, main logical
Molecular immune system in activated plant body is crossed, plant autoimmunity is improved；It is adjusted by a series of intracorporal metabolism of excitation plant
Control promotes plant roots, stem, leaf growth and improves chlorophyll content, improve crop yield, has to plurality of plant diseases higher anti-
Effect
Moroxydine Hydrochloride (Moroxydine hydrochloride) is a kind of wide spectrum, hypovirus control agent.After dilution
Medical fluid spray application to plant leaf surface after, medicament can be entered in plant by aqueous vapor hole, inhibit or destroy nucleic acid and lipoprotein
It is formed, prevents the reproduction process of virus, play the role of controlling the virus.Not only to Virus Diseases of Rice, banded sclerotial blight, full rot, red
Mildew, rice blast and the fungoid of other field crops lesion and it is bacillary have with virosis cross-infection disease it is potent anti-
It controls and malicious effect of going out, while also having good prevention and treatment to the virosis of the gourd, fruit and vegetables class such as tomato, capsicum, cucumber, rape, Chinese cabbage
And therapeutic effect.
Actual pesticide experience have shown that, repeat and single-minded apply a kind of reactive compound to prevent and treat disinfect pathogen very
It will lead to the fast selective of germ bacterial strain in more situations, it is usual at present for the risk for reducing resistance germ bacterial strain selectivity
Disinfect pathogen is prevented and treated using the mixture of different activities compound.By will have the reactive compound of different role mechanism into
Row combination, can delaying drug resistance generate, reduce amount of application, reduce control cost.
Summary of the invention
The purpose of the present invention is being directed to fungicide resistance and pedo relict problem in practical applications, filters out difference and kill
The fungicide of bacterium principle is compounded, and a kind of new microbicide compositions are obtained, to improve bactericidal agent for preventing and treating effect, delaying drug resistance
It generates, reduces amount of application, reduce control cost.
It is a further object to provide include two kinds of effective component toVerticilliumdahliaActivitie Activitie S of Relative activator proteins and morpholine hydrochloride
The preparation method of guanidine bactericidal composition and the application in agriculture field prevention and treatment corps diseases.
The purpose of the present invention can be achieved by the following measures:
A kind of microbicide compositions, the composition include two kinds of active groups of toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride
Point.
Inventor is found by experiment that composition of the invention is for preventing and treating crops bacterium or fungal disease prevention and treatment
Synergy is obvious, it is often more important that amount of application is reduced, and reduces use cost.Contain toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride
Compound structure type it is different, mechanism of action is different, and the two compounding can expand fungicidal spectrum, and can be to a certain extent
Delay generation and the development speed of pathogen resistance, and no interactions are anti-between toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride
Property.
In a preferred embodiment, the weight of active component toVerticilliumdahliaActivitie Activitie S of Relative activator protein and active component Moroxydine Hydrochloride
It can be more preferably 1:20~140 to make function and effect both become apparent from weight ratio than for 1:10~160.
The dosage form allowed on pesticide can be made by active constituent and insecticides adjuvant or auxiliary material in composition of the invention.Into one
Step, the composition forms agriculture by the active component of 1~85% parts by weight and the insecticides adjuvant of 99~15% parts by weight or auxiliary material
The dosage form allowed on medicine.
The present invention provides the bactericidal compositions comprising toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride in agriculture field
Prevent and treat the purposes in terms of corps diseases, the especially purposes in terms of the fungi or bacterial disease for preventing and treating certain crops.
Above-mentioned composition specifically may include insecticides adjuvant or auxiliary material, such as carrier, solvent, dispersing agent, wetting agent, gluing
One or more of agent, thickener, adhesive, surfactant or fertilizer etc..It can be mixed during application common
Auxiliary agent.
Suitable auxiliary agent or auxiliary material can be solid or liquid, they are usually common substance during formulation,
Such as natural or regenerated minerals, solvent, dispersing agent, wetting agent, adhesive, thickener, adhesive.
The method of administration of the present composition includes the aerial part that composition of the invention is used for plant growth, especially
It is leaf portion or blade face.It can choose seed soaking or be applied to controlling object surface.The frequency and amount of application of application depend on pathogen
Biology and weather life condition.The growth place of plant, such as rice field can be soaked with the liquid preparation of composition, or
Composition is applied in soil by person in solid form, and such as in granular form (soil application), composition can be by soil through planting
Object root enters in plant (systemic action).
Composition of the invention can be prepared into various dosage forms pesticide-acceptable, including but not limited to missible oil, suspension
Agent, wettable powder, water dispersible granules, pulvis, granula, aqua, aqueous emulsion, microemulsion, encapsulated form, mother liquor, female powder etc.,
In a kind of preferred embodiment, dosage form of the invention uses water dispersible granules, suspending agent, wettable powder.According to these compositions
Property and application composition purpose to be achieved and ambient conditions, can choose composition to be sprayed, atomizing, dust,
Broadcast sowing or sprinkle the method application poured or the like.
Composition of the invention can be prepared into various dosage forms by known method, can by effective component with help
Agent can uniformly mix together with surfactant when needing, grind, be prepared into required agent such as solvent, solid carrier
Type.
Above-mentioned solvent can be selected from aromatic hydrocarbon, preferably contain 8-12 carbon atom, such as xylene mixture or substituted benzene, phthalein
Esters of gallic acid, such as two octanoic acid of Dibutyl phthalate or phthalandione, fat hydrocarbon, such as thiacyclohexane or paraffin, the ether of pure and mild ethylene glycol and they
And ester, such as ethyl alcohol, ethylene glycol, ethylene glycol monomethyl；Ketone, such as cyclohexanone, highly polar solvent, such as N- methyl -2- pyrrolidines
Ketone, dimethyl sulfoxide or dimethylformamide and vegetable oil or vegetable oil, such as soybean oil.
Above-mentioned solid carrier, such as usually natural mineral fillers, such as talcum, kaolinite for pulvis and dispersible agent
Soil, montmorillonite or atlapulgite.In order to manage the physical property of composition, polymolecularity silicic acid or polymolecularity can also be added
Adsorpting polymerization object carrier, such as granulated adsorptive carriers or non-adsorbed carrier, suitable granulated adsorptive carriers are porous types, it is such as floating
Stone, bentonite or bentonite；Suitable non-adsorbed carrier such as calcite or sand.Further, it is possible to use a large amount of inorganic in nature or having
The prefabricated material to granulate of machine property is as carrier, especially dolomite.
The chemical property of effective component in composition according to the present invention, suitable surfactant are sulfomethylated lignin
Acid, naphthalene sulfonic acids, phenolsulfonic acid, alkali salt or amine salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, fat
Alcohol sulfate, fatty acid and sulphated fatty alcohol glycol ether, there are also the condensation product of sulfonated naphthalene and naphthalene derivatives and formaldehyde, naphthalene or
The condensation product of naphthalene sulfonic acids and phenol and formaldehyde, NONIN HS 240, ethoxylated isooctyl-phenol, octyl phenol, nonyl phenol,
Alkylaryl polyglycol ether, tributyl benzene polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol,
Ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensation product, ethoxylation polyoxypropylene, laurel acid polyethylene glycol
Ether acetal, sorbitol ester, lignin sulfite waste liquor and methylcellulose.
Two kinds of effective components show as synergistic effect in composition of the invention, and the activity of the composition is than using individualized
The independent activity of the expected summation of activity and single compound of closing object is more significant.Synergistic effect shows as allowing amount of application
Reduction, broader antifungal control spectrum, quick, more longlasting control efficiency, by a small number of applying only once or several times more
Good control plant pest fungi and broaden the possible administration interval time.These characteristics are plant epiphyte control practices
It especially needs in the process.
In terms of microbicide compositions of the invention can be applied to agriculture field prevention and treatment corps diseases, farming referred herein
Object disease especially uncinula necator, powdery mildew of cucumber, cucumber downy mildew, balsam pear powdery mildew, graw mold of tomato, wheat white powder
Disease, rice blast.But composition of the invention is other than it can prevent and treat aforementioned disease, moreover it is possible to the specific illness of prevention and treatment include but
It is not limited to wheat diseases (such as: wheat scab, wheat powdery mildew, wheat rust), rice disease (such as: rice sheath blight disease, water
Rice false smut, paddy bacterial streak etc.), maize diseases (such as: smut of maize, the leaf blight of corn, corn southern leaf blight), cucumber
Disease (such as: powdery mildew of cucumber, cucumber anthracnose, gray mold of cucumber, cucumber bacterial angular leaf spot), tomato disease are (such as: tomato
Powdery mildew, anthracnose of tomato, tomato virus disease, tomato bacterial angular leaf spot etc.), grape disease (such as: downy mildew of garpe, grape
Gray mold), apple disease (such as: ring rot of apple, apple anthracnose), citrus disease (such as: citrus scab simultaneously, citrus anthrax
Disease), tobacco diseases (such as: wildfire, Alternaria alternate), rape disease (such as: sclerotinia sclerotiorum), cotton disease (such as: cotton
Flower verticillium wilt, cotton wilt) etc..
Other features that bactericidal composition of the invention is shown are main are as follows: 1, composition mixture of the invention have it is obvious
Synergistic effect；2, since two single dose chemical structures of this composition are widely different, the mechanism of action is entirely different, and there is no hand over
Mutual resistance can delay two single doses that generated resistance problem is used alone；3, composition of the invention is to crop safety, preventive effect
It is good.Tests prove that microbicide compositions chemical property of the present invention is stablized, synergy is significant, shows significantly to controlling object
Synergy and complementation.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not used to limit
The fixed present invention, any modifications, equivalent replacements and improvementsmade within the spirit and principles of the invention, etc. should be included in
Within protection scope of the present invention.
Percentage is weight percentage in all formulas of following embodiment.The processing work of the various preparations of the present composition
Skill is the prior art, can be varied according to different situations.
One, dosage form prepares embodiment
(1) processing and embodiment of wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein, Moroxydine Hydrochloride and various auxiliary agents and filler etc. are sufficiently mixed in proportion, through super
Wettable powder is made after crushing in slimer.
Embodiment 1:63% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 3%, Moroxydine Hydrochloride 60%, alkyl sulfate 4.5%, ammonium sulfate 3.2%, polyoxy
Ethylene triphenylethylene phosphenylic acid salt 5.1%, white carbon black complements to 100%.
Embodiment 2:66.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 2.5%, Moroxydine Hydrochloride 64%, aromatic sulphonate 4.1%, alkyl phenol polyoxy second
Cyclohexene carboxaldehyde condensate sulfate 3.8%, urea 2.5%, kaolin complements to 100%.
(2) processing and embodiment of water dispersible granules
It by toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride, is mixed according to the formula uniformly with auxiliary agent and filler, warp
Air-flow crushing adds a certain amount of water mixing extrusion granulation at wettable powder, and water dispersible granules are made after dry screening
Product.
Embodiment 3:41% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride water dispersible granules
ToVerticilliumdahliaActivitie Activitie S of Relative Activating protein-1 %, Moroxydine Hydrochloride 40%, polymerization of carboxylic acid sodium salt 4.3%, alkyl naphthalene formaldehyde condensation
Object sulfonate 6.6%, aluminium chloride 3.1%, aluminium-magnesium silicate 1.2%, precipitated calcium carbonate complements to 100%.
Embodiment 4:50.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride water dispersible granules
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.5%, Moroxydine Hydrochloride 50%, lignosulfonates 6.8%, dodecyl sulphate
Sodium 5.8%, bentonite 5%, sodium alginate 4%, kaolin complements to 100%.
Embodiment 5:40.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride water dispersible granules
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.5%, Moroxydine Hydrochloride 40%, formaldehyde condensate sulfonate 8.8%, alkyl fourth two
Acid ester sulfonates 6.9%, urea 4%, aluminium-magnesium silicate 3.8%, attapulgite complements to 100%.
(3) processing and embodiment of suspending agent
By toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride, pressed with each components such as dispersing agent, wetting agent, thickener and water
The ratio of formula is uniformly mixed, and after sand milling and/or high speed shear, obtains semi-finished product, and water supplement is uniformly mixed filtering after analysis
It gets product.
Embodiment 6:30.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride suspending agent
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.5%, Moroxydine Hydrochloride 30%, naphthalenesulfonic acid-formaldehyde condensate 5%, styryl
Phenol polyoxyethylene ether 6.4%, xanthan gum 2.5%, aluminium chloride 5.8%, cyclohexanone 10%, organosilicon 0.2%, water complements to
100%.
Embodiment 7:30.25% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride suspending agent
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.25%, Moroxydine Hydrochloride 30%, copolymer-maleic anhydride sodium salt 6.8%, alkyl
Naphthalene formaldehyde condensate sulfonates 7.6%, gelatin 3.4%, ammonium sulfate 6.3%, ethylene glycol 14%, higher alcohols 0.4%, water complements to
100%.
Embodiment 8:35.25% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride suspending agent
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.25%, Moroxydine Hydrochloride 35%, alkyl naphthalene formaldehyde condensate sulfonate 7.2%,
APES formaldehyde condensation products sulfat 6.9%, hydroxylated cellulose 4.2%, ammonium sulfate 4.4%, dimethylbenzene 10%,
Organosilicon 0.8%, water complements to 100%.
Embodiment 9:33% toVerticilliumdahliaActivitie Activitie S of Relative activator protein Moroxydine Hydrochloride suspending agent
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 3%, Moroxydine Hydrochloride 30%, organosilicon 0.6%, naphthalenesulfonic acid-formaldehyde condensate
3.8%, ethylene glycol 15%, hydroxylated cellulose 3.9%, ammonium sulfate 4.4%, higher alcohols 0.3%, water complements to 100%.
Two, drug effect verification test
(1) Assays Example
The incidence that whole strain blade is investigated according to test grade scale, calculates disease index and control efficiency.
Control efficiency is converted into probability value (y), liquor strength (μ g/ml) is converted into logarithm (x), with least square method
Concentration EC50 in calculating virulence equation and inhibiting, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to Sun Yunpei's Method.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
Percentage composition+B medicament toxicity index * the mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
The percentage composition of middle B
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] * 100
CTC≤80, composition show as antagonism, 80 < CTC < 120, and composition shows as summation action, and CTC >=
120, composition shows as synergistic effect.
1, toVerticilliumdahliaActivitie Activitie S of Relative activator protein is compounded with Moroxydine Hydrochloride tests lotus rhizome mosaic virus toxicity test
1. toVerticilliumdahliaActivitie Activitie S of Relative activator protein of table is compounded with Moroxydine Hydrochloride to lotus rhizome mosaic virus toxicity test result point
Analysis
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein | 8.35 | 100.00 | \ | \ |
| Moroxydine Hydrochloride | 39.63 | 21.07 | \ | \ |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:1 | 11.83 | 70.57 | 60.54 | 116.58 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:10 | 23.79 | 35.10 | 28.25 | 124.27 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:20 | 26.69 | 31.29 | 24.83 | 126.01 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:40 | 26.82 | 31.13 | 23.00 | 135.39 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:60 | 27.21 | 30.68 | 22.36 | 137.20 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:80 | 26.39 | 31.64 | 22.04 | 143.53 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:100 | 27.33 | 30.55 | 21.85 | 139.81 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:120 | 29.32 | 28.48 | 21.72 | 131.09 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:140 | 30.46 | 27.41 | 21.63 | 126.72 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:160 | 31.92 | 26.16 | 21.56 | 121.33 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: Moroxydine Hydrochloride=1:170 | 32.75 | 25.49 | 21.53 | 118.40 |
As a result (table 1) shows in toVerticilliumdahliaActivitie Activitie S of Relative activator protein: in Moroxydine Hydrochloride=1:10~160 interval ranges, pole
Alternaria tenuis activator protein is compounded with Moroxydine Hydrochloride significantly improves the control efficiency of lotus rhizome mosaic virus, illustrates that the two is multiple
Pairing lotus rhizome mosaic virus prevention and treatment has significant synergistic effect.
(2) field efficacy verification test
Test method: it at the initial stage of a disease, carries out for the first time by spraying, carrying out being administered for second after 7 days immediately, each processing 4
A cell, each 20 square meter of cell.11 days investigation statistics incidences, 5 points of each cell are random before medicine and after second of medicine
Sampling, 5 plants of crops of every investigation, the lesion area for investigating every blade in whole strain account for percentage and the classification of blade area, calculate
Disease index and control efficiency.
It is expected that preventive effect (%)=X+Y-XY/100 (wherein, X, Y are single dose preventive effect)
Grade scale:
0 grade: disease-free spot；
1 grade: leaf spot lesion is less than 5, and length is less than 1cm；
3 grades: leaf spot lesion 6-10, part scab length is greater than 1cm；
5 grades: leaf spot lesion 11-25, part scab is linked to be piece, and lesion area accounts for the 10-25% of leaf area；
7 grades: leaf spot lesion 26 or more, scab is linked to be piece, and lesion area accounts for the 26-50% of leaf area；
9 grades: scab is linked to be piece, lesion area account for 50% of leaf area or more or full leaf it is withered.
1, toVerticilliumdahliaActivitie Activitie S of Relative activator protein compounds field efficacy experiment with Moroxydine Hydrochloride
2 toVerticilliumdahliaActivitie Activitie S of Relative activator protein of table and Moroxydine Hydrochloride mixture are to eggplant virus disease control effect
Measurement result (table 2) shows that toVerticilliumdahliaActivitie Activitie S of Relative activator protein and compounding for Moroxydine Hydrochloride are anti-to eggplant virosis
Effect significantly improves, and illustrates that the two compounding has significant synergistic effect to eggplant virosis.
Claims (7)
1. a kind of microbicide compositions, it is characterised in that the composition includes toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Moroxydine Hydrochloride two
Kind active component, wherein the weight ratio between two components is 1:10~160.
2. composition according to claim 1, it is characterised in that active component toVerticilliumdahliaActivitie Activitie S of Relative activator protein and active group
The weight ratio for dividing Moroxydine Hydrochloride is 1:20~140.
3. composition according to claim 1 or 2, it is characterised in that the composition is by active constituent and insecticides adjuvant or auxiliary
The dosage form allowed on pesticide is made in material.
4. composition according to claim 3, it is characterised in that the composition by 1~85% parts by weight active component with
The dosage form allowed on insecticides adjuvant or auxiliary material the composition pesticide of 99~15% parts by weight.
5. composition according to claim 3, it is characterised in that the dosage form be water dispersible granules, wettable powder or
Suspending agent.
6. composition according to claim 3 or 4, it is characterised in that the insecticides adjuvant or auxiliary material be selected from carrier, solvent,
One or more of dispersing agent, wetting agent, adhesive, thickener, adhesive, surfactant or fertilizer.
7. purposes of the composition described in claim 1~6 any one in terms of agriculture field prevents and treats corps diseases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102696654A (en) * | 2012-05-31 | 2012-10-03 | 利尔化学股份有限公司 | Composition having antiviral action, pesticide and application thereof |
| CN109042011A (en) * | 2018-07-31 | 2018-12-21 | 湖南华诚高科生态农业有限公司 | A method of preventing Siraitia grosvenorii virosis |
| CN109315400A (en) * | 2018-10-23 | 2019-02-12 | 江苏辉丰生物农业股份有限公司 | A kind of microbicide compositions |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102696654A (en) * | 2012-05-31 | 2012-10-03 | 利尔化学股份有限公司 | Composition having antiviral action, pesticide and application thereof |
| CN109042011A (en) * | 2018-07-31 | 2018-12-21 | 湖南华诚高科生态农业有限公司 | A method of preventing Siraitia grosvenorii virosis |
| CN109315400A (en) * | 2018-10-23 | 2019-02-12 | 江苏辉丰生物农业股份有限公司 | A kind of microbicide compositions |
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| "贵州农业实用技术"全书编辑委员会编写: "《农作物生产》", 31 March 1997, 贵州科技出版社 * |
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