CN109884993A - A kind of pharmacy digitlization workshop management system - Google Patents
A kind of pharmacy digitlization workshop management system Download PDFInfo
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- CN109884993A CN109884993A CN201910037736.9A CN201910037736A CN109884993A CN 109884993 A CN109884993 A CN 109884993A CN 201910037736 A CN201910037736 A CN 201910037736A CN 109884993 A CN109884993 A CN 109884993A
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- 238000007726 management method Methods 0.000 claims abstract description 47
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- 238000003860 storage Methods 0.000 claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 claims description 37
- 238000012544 monitoring process Methods 0.000 claims description 22
- 238000004891 communication Methods 0.000 claims description 16
- 238000005265 energy consumption Methods 0.000 claims description 13
- 238000004088 simulation Methods 0.000 claims description 10
- 239000002994 raw material Substances 0.000 claims description 9
- 238000004458 analytical method Methods 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 5
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- 238000002360 preparation method Methods 0.000 claims description 4
- 238000004422 calculation algorithm Methods 0.000 claims description 3
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- 238000012797 qualification Methods 0.000 claims description 3
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract
The present invention discloses a kind of pharmacy digitlization workshop management system, the understanding that early period passes through technique and process to pharmacy corporation, it analyzes and formulates Digital Realization step, in integrated planning, technical flow design and the network architecture planning for completing to carry out digitlization workshop on the basis of automation, technical flow design and digitalized artificial are realized；Carrying out each critical component by SCADA system includes the acquisition of the data such as valve, pressure gauge, weighing, and is analyzed, and automatically generates batch report, gives warning in advance to unit exception；By implementing the software systems such as MES, LIMS, TMI-S, with the system integrations such as existing ERP, OA, supervision code, get through enterprise's full supply chain management, complete whole process retrospect, realize the digitlization and informationization of research and development, technique, simulating, verifying, material circulation and storage, which really improves work efficiency, reduces cost of labor.
Description
Technical field
The present invention relates to medicament compartment administrative skill field, specifically a kind of pharmacy digitizes workshop management system.
Background technique
In the prior art, pharmacy management system is generally split settings, single-set operation, manages and controls, and lacks a set of energy
The intelligent information management system of entire pharmaceutical manufacturing facility information, single machine dispersion, handled by itself operational management are reacted comprehensively
The othernesses such as biggish randomness, asynchronous, uncoordinated are respectively present, so that influencing production effect and efficiency, and are closed
Property it is also poor, while to enterprise realize intellectualization of factories management bring very big obstacle.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of pharmacy to digitize workshop management system, to solve existing skill
Defect present in art.
The technical scheme to solve the above technical problems is that
A kind of pharmacy digitlization workshop management system comprising the MES system being connect with digitlization workshop, the MES system
System is separately connected SCSDA system, pharmaceutical industry energy consumption management system EMS and TMI-S intelligent logistics system, the SCSDA system
Multiple equipment is connected, is respectively used to acquire temperature and humidity, current/voltage, pressure, flow and weight signal in each equipment；Institute
Stating TMI-S intelligent logistics system includes TQS quality tracing module, M-WMS storehouse management module and ITS intelligent transportation system, reality
Now from supplementary material to the entire production process of finished product；The pharmaceutical industry energy consumption management system EMS include energy source monitoring module,
Data management module and energy consumption analysis module；
Further, the MES system includes production planning management module, process route management module, raw materials control mould
Block, Container Management module, production process control management module and on-site data gathering module；
Wherein, the production planning management module is according to name of product and yield manual creation work order and batch number, and can
With receive from factory's upper layer ERP system issue containing name of product, yield, the work order of batch number information；
The process route management module specifies different process routes according to different product, different batches information, together
When support to optimize prior art route on the basis of new edition GMP and enterprise's existing condition of production；
The raw materials control module encodes raw material to control material investment and output, and coding is locked after generating
Determine into production process, material mixed batch is effectively prevent, and material information is stored in database by way of coding, with batch
Number, the information such as electronic supervision code be linked, traced at any time according to product coding information convenient for user.
The Container Management module is subject to various preparations to the metering of medicament and puts into containers, and there are many classes for container
Type is tied under different production batch respectively and is operated；
The production process control management module is operated by operation, the limitation for prompting staff currently to need to carry out
Permission, the critical data for managing production process manage the key operation of production process to promote the qualification rate of enterprise product；
Further, the SCSDA system include monitoring computer, remote-terminal unit, programmable logic controller (PLC),
The communications infrastructure, man-machine interface, in which:
The monitoring computer collects process data and sends control command to the equipment of joint connection in site；
The remote-terminal unit be connected to during sensor and actuator, and with supervisory computer system join
Net；
The programmable logic controller (PLC) be connected to during sensor and actuator, and with side identical with RTU
Formula is networked to monitoring system；
Supervisory computer system is connected to remote-terminal unit and PLC by the communications infrastructure, and can be made
With professional standard or manufacturer's proprietary protocol；
The man-machine interface is operator's window of monitoring system, it provides work to operator in the form of simulation drawing
Factory's information, simulation drawing are the schematic diagram for controlling factory, and alarm and the logout page.HMI is connected to SCADA monitoring and calculates
Machine provides real time data to drive simulation drawing, and alarm is shown and tendency chart；
The on-site data gathering module adopts the currently running data of field device by data collection system
Collection, avoids staff from needing manual confirmation value data when filling in record and fills in the whether accurate problem of numerical value, greatly may be used
Avoid to energy the generation of mistake；
Further, the ITS intelligent transportation system, priority-based AGV path allocation system, be based on script skill
The AGV task scheduling system of art, the AGV route search system based on unidirectional ring and A star algorithm realize logistics closed loop, AGV transport
Efficient, the collaboration for reaching conveying, copying mechanically, producing that system is unmanned, AS/RS is stored.
The beneficial effects of the present invention are: digitlization workshop can realize the unmanned and with no paper of most of technique, user
Without manually recorded and fill in, automatic data collection and analysis, strong historical data is provided for system optimization and knows decision；
It is remotely controlled and is monitored by centralized control system, realized independently cooperateing with and interconnecting between equipment, really mention
High efficiency reduces cost of labor.
Detailed description of the invention
Fig. 1 is schematic structural view of the invention；
Specific embodiment
The principle and features of the present invention will be described below with reference to the accompanying drawings, and the given examples are served only to explain the present invention, and
It is non-to be used to limit the scope of the invention.
1 pair of system modules describes in detail with reference to the accompanying drawing.
Pharmaceutical industry MES management system function:
1. production planning management
Pharmaceutical industry MES system is supported according to name of product and yield manual creation work order and batch number, while can be connect
By the work order containing information such as name of product, yield, batch numbers issued from factory's upper layer ERP system.
2. process route management
Pharmaceutical industry MES system specifies different process routes according to different product, different batches information, while supporting
Prior art route is optimized on the basis of the existing condition of production of new edition GMP and enterprise.
3. raw materials control
Pharmaceutical industry MES system controls material investment and output by being encoded to raw material, by it after coding generation
Be locked in production process, effectively prevent material mixed batch, and material information is stored in database by way of coding, with batch
Secondary number, the information such as electronic supervision code be linked, traced at any time according to product coding information convenient for user.
4. Container Management
The whole metering of medicine preparation production is subject to various preparations and puts into containers, and there are many types for container in MES system.
Container is chiefly used in Weighing module in pharmacy corporation, when needing vehicle of sterilization tool to carry out disinfecting action whole sterilising prods, can go out
Now with cabinet difference batch the case where, the generation criticized is mixed in order to prevent, vehicle of sterilization can be had and be considered as container, be tied to different lifes respectively
It produces and is operated under batch.
5. production process control management
The core content of MES system is operated by the operation, the limitation that effectively prompt staff currently to need to carry out
Permission, the critical data for managing production process manage the key operation of production process to promote the qualification rate of enterprise product, make to look forward to
Product data standardization, the production procedure standardization of industry, it is ensured that enterprise product information is complete, standardizes, and reaches promotion enterprise eventually and produces
Quality and the purpose for promoting corporate image.
6. on-site data gathering
Pharmacy MES system solution is acquired the currently running data of field device by data collection system,
It avoids staff from needing manual confirmation value data when filling in record and fills in the problems such as whether numerical value is accurate, greatly may
Ground avoids the generation of mistake.In addition, advanced report can also be provided for intelligent production and performance management tools and data analyze function
Energy and instrument board, by means of this, user can convert valuable information for data collected in production process.
Pharmaceutical industry MES management system is constituted:
One, SCADA system:
Usual SCADA system is divided into two levels, i.e. client/server architecture.Server is communicated with hardware device,
Carry out data processing and operation.And client is used for human-computer interaction, such as uses the state of text, animation displaying scene, and can be to existing
Switch, the valve of field are operated.There are also a kind of " very-long-range clients ", it can be issued by Web and be carried out on internet
Monitoring.It can both be connected by point to point system hardware device (such as PLC), and server can also be connected to bus mode
On.Generally by serial ports (RS232), bus mode can be RS485, the connection types such as Ethernet for point-to-point connection.It uses
SCADA concept can construct large-scale and mini-system.The range of these systems can be from tens to thousands of a control loops, specifically
Depending on application.Example flow includes industry, infrastructure and the process based on facility, and industrial process includes manufacture, excessively program-controlled
System generates electricity, manufacture and refining, and can be continuous, interval, repeats or discrete mode is run.
SCADA system is mainly made of following part: monitoring computer, remote-terminal unit (RTU), programmable logic control
Device (PLC) processed, the communications infrastructure, man-machine interface (HMI).
1, monitor computer: this is the core of SCADA system, collects process data and sends to the equipment of joint connection in site and controls
System order.It, which refers to, is responsible for the computer and software that communicate with joint connection in site controller, these joint connection in site controllers be RTU with
PLC, including operating in the HMI software on operator workstation.In lesser SCADA system, monitoring computer may be by one
Platform PC composition, in this case, HMI is a part of this computer.In large-scale SCADA system, main website may include
The HMI of more trustships on client computers, multiple servers are acquired for data, distributed software application and calamity
It is difficult to recover website.In order to improve the integrality of system, multiple servers are typically configured to dual redundant or stand-by heat form, so as to
Lasting control and monitoring are provided in the case where server failure or failure.Remote-terminal unit
2, remote-terminal unit: also referred to as (RTU), sensor and actuator during being connected to, and calculated with monitoring
Machine systems connection.RTU is " intelligent I/O ", and usually has the function of embedded Control, such as ladder logic, to realize boolean
Logical operation.
3, programmable logic controller (PLC): also referred to as PLC, they be connected to during sensor and actuator, and with
The identical mode of RTU is networked to monitoring system.Compared with RTU, PLC has the function of more complicated embedded Control, and uses
One or more IEC 61131-3 programming languages are programmed.PLC is usually utilized to replace RTU as field device, because it
It is more economical, it is multi-functional, flexibly and it is configurable.
4, the communications infrastructure: supervisory computer system is connected to remote-terminal unit (RTU) and PLC by this, and can
To use professional standard or manufacturer's proprietary protocol.The last one order that RTU and PLC uses monitoring system to provide, in mistake
The near real-time of journey controls lower autonomous operation.The failure of communication network not necessarily stops the process control of factory, and extensive
When communicating again, operator can continue to monitor and control.Some critical systems will have dual redundant Data highway, lead to
Often it is attached by different routes.
5, man-machine interface: man-machine interface (HMI) is operator's window of monitoring system.It is in the form of simulation drawing to operation
Personnel provide plant information, and simulation drawing is the schematic diagram for controlling factory, and alarm and the logout page.HMI is connected to
SCADA monitors computer, provides real time data to drive simulation drawing, alarm is shown and tendency chart.In many installations, HMI is
The graphic user interface of operator, collects all data from external equipment, and creation report executes alarm, sends notice etc..
Simulation drawing or can be covered by being used to indicate that the line chart of processes element and schematic symbols form by the digital photos of process equipment
Animated character composition.
The monitor operation of factory is carried out by HMI, and operator uses mouse pointer, and keyboard and touch screen issue life
It enables.For example, the symbol of pump can show that pump is currently running to operator, and flowmeter symbol can show and be pumped by pipeline
How many fluid.Operator can be clicked by mouse or screen touch is from simulator switchable pump.HMI is by fluid in display pipes
Flow reduce in real time.
The HMI packet of SCADA system generally comprises a mapping program, and operator or system maintenance personnel are used to change these
The representation of point in the interface.These expressions can be simple as traffic lights on the screen, represents practical in scene
The state of traffic lights, it is perhaps complicated as the multi-projector display for representing the position of all elevators in skyscraper or
Train on whole trains.
" historical record " is a software service in HMI, the data of its storage tape timestamp in the database, event and
Alarm, can inquire or for filling the graphical trend in HMI.Historian is the visitor from data acquisition server request data
Family end [3]
Software aspects: SCADA is made of many tasks, and each task completes specific function.Positioned at one or more machines
Server on device is responsible for data acquisition, data processing (such as range swithching, filtering, alarm inspection, calculating, logout, history
Storage, execution user's script etc.).It can mutually be communicated between server.If server is further individually divided by some systems
Dry specialized server, such as Alarm Server record server, history server, login service device etc..Make in each server logic
To be unified whole, but physically it is likely to be positioned on different machines.The benefit of classifying and dividing can be by multiple servers
Various data unified managements are shared out the work and helped one another, the disadvantage is that low efficiency, local fault may influence whole system.
Communication aspects: the communication in SCADA system is divided into internal communication, communicates with I/O equipment and extraneous communication.Client
General there are three types of communication form between server and between server and server, on-demand subscribes to formula and broadcast type.Equipment is driven
Dynamic program and I/O device talk generally use on-demand, and most of equipment all support this communication modes, the equipment also having certainly
Support active transmission mode.SCADA communication with the outside world in several ways.Such as OPC, OPC client generally can be all provided, be used to
The opc server provided with equipment manufacturer communicates.Because of the standard that OPC has Microsoft default, OPC client is without repairing
The opc server that changing can provide with each is communicated.
Two, pharmaceutical industry energy consumption management system EMS:
Pharmaceutical industry energy consumption management system is extremely important, including the energy and energy consumption data acquisition, data statistics and analysis, intelligence
Energyization inquiry and service management, system function include following aspects:
1, energy source monitoring: the energy flow chart picture of various energy mediums shows implementation Process data, meter state, alarm signal
Cease the various energy process flow monitoring such as picture way；
2, data management: has the data-interface with PLC, serial server meter etc., data can two-way flow.Acquisition temperature
Degree pressure, transfinites, the parameters such as start and stop temperature rise rate, and production history data and trend, automatic report generation, also has parameter
History playback, parameter curve generates relatively etc.；
3, energy consumption analysis: system can be collected arrangement to energy consumption data, carry out energy consumption point by subsidiary factory, workshop, product
The ability of analysis, can in conjunction with cost analysis.Efficiency data accumulation, the spacecraft long-term operation management of the correct assessment equipment of comparison, more rationally
Reducing energy consumption measure, realize efficiency quantitative analysis.
Three, TMI-S intelligent logistics system:
Based on logistics legal, control system in field, exclusively for a whole set of Intelligent logistics system of pharmaceuticals industry exploitation, design
System, realize reliable product back-tracing, multisystem communication and control, whole process closed-loop logistics collaboration, help enterprise realize manpower at
This reduction, logistic efficiency are promoted, and memory space is promoted, logistic storage is unmanned, high efficiency, and main includes following several parts:
1, TQS quality tracing system (Tracking Quality System): raw material retrospect, prevents people at finished product retrospect
Member's interference, production process transparence；
2, M-WMS control system (Mutual Warehouse Management System): multisystem docking, multisystem
Communication, more equipment collaborations, storage and handling of goods and materials；
3, ITS intelligent transportation system (Intelligent Transport System): the path AGV point priority-based
Match system, the AGV task scheduling system based on script technology, the AGV route search system based on unidirectional ring and A star algorithm, it is real
Existing logistics closed loop, AGV transportation system be unmanned, AS/RS storage efficient, the collaboration for reaching conveying, copying mechanically, producing.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (4)
1. a kind of pharmacy digitizes workshop management system, it is characterised in that: including the MES system being connect with digitlization workshop, institute
It states MES system and is separately connected SCSDA system, pharmaceutical industry energy consumption management system EMS and TMI-S intelligent logistics system, it is described
SCSDA system connects multiple equipment, is respectively used to acquire temperature and humidity in each equipment, current/voltage, pressure, flow and again
Measure signal；The TMI-S intelligent logistics system includes that TQS quality tracing module, M-WMS storehouse management module and ITS are intelligently transported
Defeated system is realized from supplementary material to the entire production process of finished product；The pharmaceutical industry energy consumption management system EMS includes the energy
Monitoring module, data management module and energy consumption analysis module.
2. a kind of pharmacy according to claim 1 digitizes workshop management system, it is characterised in that: the MES system packet
Include production planning management module, process route management module, raw materials control module, Container Management module, production process control pipe
Manage module and on-site data gathering module；
Wherein, the production planning management module is according to name of product and yield manual creation work order and batch number, and can connect
By from factory's upper layer ERP system issue containing name of product, yield, the work order of batch number information；
The process route management module specifies different process routes according to different product, different batches information, props up simultaneously
It holds and prior art route is optimized on the basis of new edition GMP and enterprise's existing condition of production；
The raw materials control module encodes raw material to control material investment and output, and coding locks itself into after generating
In production process, effectively prevent material mixed batch, and material information is stored in database by way of coding, with batch number,
The information such as electronic supervision code are linked, and are traced at any time according to product coding information convenient for user.
The Container Management module is subject to various preparations to the metering of medicament and puts into containers, container there are many type, point
It is not tied under different production batch and is operated；
The production process control management module passes through the operation for prompting staff currently to need to carry out, limitation operating rights
Limit, manages the key operation of production process to promote the qualification rate of enterprise product at the critical data of control production process.
3. a kind of pharmacy according to claim 1 digitizes workshop management system, it is characterised in that: the SCSDA system
System includes monitoring computer, remote-terminal unit, programmable logic controller (PLC), the communications infrastructure, man-machine interface, in which:
The monitoring computer collects process data and sends control command to the equipment of joint connection in site；
The remote-terminal unit be connected to during sensor and actuator, and with supervisory computer system network；
The programmable logic controller (PLC) be connected to during sensor and actuator, and joined in a manner of identical with RTU
Net is to monitoring system；
Supervisory computer system is connected to remote-terminal unit and PLC by the communications infrastructure, and row can be used
Industry standard or manufacturer's proprietary protocol；
The man-machine interface is operator's window of monitoring system, it provides factory's letter to operator in the form of simulation drawing
Breath, simulation drawing are the schematic diagram for controlling factory, and alarm and the logout page.HMI is connected to SCADA monitoring computer,
Real time data is provided to drive simulation drawing, alarm is shown and tendency chart；
The on-site data gathering module is acquired the currently running data of field device by data collection system, keeps away
Exempt from staff to need manual confirmation value data when filling in record and fill in the whether accurate problem of numerical value, possibly keep away greatly
Exempt from the generation of mistake.
4. a kind of pharmacy according to claim 1 digitizes workshop management system, it is characterised in that: the ITS intelligence
Transportation system, priority-based AGV path allocation system, the AGV task scheduling system based on script technology, be based on unidirectional ring
With the AGV route search system of A star algorithm, realizes that logistics closed loop, AGV transportation system are unmanned, AS/RS storage efficient, reach
To the collaboration for conveying, copying mechanically, producing.
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| CN110347136A (en) * | 2019-08-02 | 2019-10-18 | 长春融成智能设备制造股份有限公司 | A kind of digital simulation method based on OPC intelligence chemical industry equipment |
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