CN109876178A - A kind of stoma leakproof patch and preparation method thereof - Google Patents
A kind of stoma leakproof patch and preparation method thereof Download PDFInfo
- Publication number
- CN109876178A CN109876178A CN201910344642.6A CN201910344642A CN109876178A CN 109876178 A CN109876178 A CN 109876178A CN 201910344642 A CN201910344642 A CN 201910344642A CN 109876178 A CN109876178 A CN 109876178A
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- China
- Prior art keywords
- stoma
- acid esters
- propylene acid
- weight propylene
- leakproof
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- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 150000002148 esters Chemical class 0.000 claims abstract description 77
- 239000002253 acid Substances 0.000 claims abstract description 76
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims abstract description 75
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims abstract description 75
- 229920001971 elastomer Polymers 0.000 claims abstract description 67
- 239000000806 elastomer Substances 0.000 claims abstract description 67
- 239000000853 adhesive Substances 0.000 claims abstract description 59
- 230000001070 adhesive effect Effects 0.000 claims abstract description 59
- 229920000642 polymer Polymers 0.000 claims abstract description 57
- 239000011347 resin Substances 0.000 claims abstract description 51
- 229920005989 resin Polymers 0.000 claims abstract description 51
- 239000000945 filler Substances 0.000 claims abstract description 34
- 239000004014 plasticizer Substances 0.000 claims abstract description 31
- 230000002745 absorbent Effects 0.000 claims abstract description 26
- 239000002250 absorbent Substances 0.000 claims abstract description 26
- 239000000463 material Substances 0.000 claims abstract description 20
- 238000010030 laminating Methods 0.000 claims abstract description 14
- 239000000758 substrate Substances 0.000 claims abstract description 10
- 239000004033 plastic Substances 0.000 claims description 30
- 238000002156 mixing Methods 0.000 claims description 13
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 11
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 10
- 239000002994 raw material Substances 0.000 claims description 10
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 10
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- 150000003505 terpenes Chemical class 0.000 claims description 10
- 235000007586 terpenes Nutrition 0.000 claims description 10
- 125000004122 cyclic group Chemical group 0.000 claims description 8
- 239000011230 binding agent Substances 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 4
- 229940048053 acrylate Drugs 0.000 claims description 4
- PQUXFUBNSYCQAL-UHFFFAOYSA-N 1-(2,3-difluorophenyl)ethanone Chemical compound CC(=O)C1=CC=CC(F)=C1F PQUXFUBNSYCQAL-UHFFFAOYSA-N 0.000 claims description 3
- RSWGJHLUYNHPMX-UHFFFAOYSA-N Abietic-Saeure Natural products C12CCC(C(C)C)=CC2=CCC2C1(C)CCCC2(C)C(O)=O RSWGJHLUYNHPMX-UHFFFAOYSA-N 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 3
- 229920002907 Guar gum Polymers 0.000 claims description 3
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims description 3
- KHPCPRHQVVSZAH-HUOMCSJISA-N Rosin Natural products O(C/C=C/c1ccccc1)[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KHPCPRHQVVSZAH-HUOMCSJISA-N 0.000 claims description 3
- 229920001400 block copolymer Polymers 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 239000008273 gelatin Substances 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 239000000665 guar gum Substances 0.000 claims description 3
- 235000010417 guar gum Nutrition 0.000 claims description 3
- 229960002154 guar gum Drugs 0.000 claims description 3
- 150000004678 hydrides Chemical class 0.000 claims description 3
- 239000001814 pectin Substances 0.000 claims description 3
- 235000010987 pectin Nutrition 0.000 claims description 3
- 229920001277 pectin Polymers 0.000 claims description 3
- 229940047670 sodium acrylate Drugs 0.000 claims description 3
- KHPCPRHQVVSZAH-UHFFFAOYSA-N trans-cinnamyl beta-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OCC=CC1=CC=CC=C1 KHPCPRHQVVSZAH-UHFFFAOYSA-N 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- 229920002785 Croscarmellose sodium Polymers 0.000 claims description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 2
- -1 acrylic ester Chemical class 0.000 claims description 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 2
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 2
- 239000007800 oxidant agent Substances 0.000 claims 2
- 230000001590 oxidative effect Effects 0.000 claims 2
- 239000003292 glue Substances 0.000 claims 1
- 239000003208 petroleum Substances 0.000 claims 1
- 210000003608 fece Anatomy 0.000 abstract description 8
- 239000007788 liquid Substances 0.000 abstract description 8
- 201000004624 Dermatitis Diseases 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 5
- 230000002265 prevention Effects 0.000 abstract description 4
- 238000012360 testing method Methods 0.000 description 16
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 8
- 238000004132 cross linking Methods 0.000 description 8
- 238000005213 imbibition Methods 0.000 description 8
- 239000002562 thickening agent Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 230000008676 import Effects 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 229910000831 Steel Inorganic materials 0.000 description 5
- 239000010959 steel Substances 0.000 description 5
- 239000006071 cream Substances 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000004902 Softening Agent Substances 0.000 description 2
- 235000010489 acacia gum Nutrition 0.000 description 2
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 2
- 229920000344 molecularly imprinted polymer Polymers 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000012661 block copolymerization Methods 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 229940105329 carboxymethylcellulose Drugs 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000007719 peel strength test Methods 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
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- 230000009466 transformation Effects 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Landscapes
- Adhesives Or Adhesive Processes (AREA)
Abstract
The invention discloses a kind of stoma leakproof patch and preparation method thereof, patch includes: plasticity adhesive phase, the laminating release layer in plasticity adhesive phase；The formula of plasticity adhesive includes: adhesive substrate according to mass percent: high-molecular-weight propylene acid esters elastomer 10-50%, plasticizer: low molecular weight propylene acid esters elastomer 5-30%, tackifier: tackifying resin 5-30%, filler: absorbent polymer polymer 10-40%；Leakproof patch of the present invention only needs to open separated type material when in use, pastes according to the direct plasticity of stoma shapes and sizes, and cooperation stoma chassis use can play the effect of leakproof, easy to operate；The selection of formula has good effect to the prevention and treatment of liquid dung dermatitis；And simplify step of preparation process, reduce cost.
Description
Technical field
The present invention relates to stoma patch field, especially a kind of stoma leakproof patch and preparation method thereof.
Background technique
Liquid dung dermatitis is one of common complication after enterostomy, accounts for stoma scytitis for a long time
22%, the erosion of stoma skin is mainly caused due to liquid dung stimulation.Since patient size, stoma are concurrent after neostomy
Disease and operation need that a variety of causes is waited to be easy to cause stoma surrounding skin uneven, lead to excrement not easily collecting, stoma bottom
Disk is easy leakage, so as to cause liquid dung dermatitis.Liquid dung dermatitis tempo is very fast, once it is difficult to not only increase nursing
Degree, also makes patient pain unbearably.
Existing stoma leakproof product is mainly leakproof cream, and leakproof cream is needed to squeeze out from pipe when in use, is then applied to
Stoma recess and stoma periphery, sticky lotion is not only difficult to be squeezed out from pipe, but also also extremely difficult removing after stickup.Meanwhile
Commercially available leakproof cream contains alcohol mostly, there is certain stimulation to stoma surrounding skin.
Market needs one kind more convenient when using compared to leakproof cream, and application method is easier to grasp, convenience, wearing
Property and it is easy all excellent leakproof product of removing property, the present invention solves such problems.
Summary of the invention
To solve the deficiencies in the prior art, the purpose of the present invention is to provide a kind of stoma leakproof patches and its preparation side
Method plasticity leakproof patch, it is easy to operate, there is good effect to the prevention and treatment of liquid dung dermatitis.
In order to achieve the above objectives, the present invention adopts the following technical scheme that:
A kind of stoma leakproof patch, comprising: plasticity adhesive phase, the laminating release layer in plasticity adhesive phase；
The formula of plasticity adhesive includes: adhesive substrate according to mass percent: high-molecular-weight propylene acid esters elastomer 10-
50%, plasticizer: low molecular weight propylene acid esters elastomer 5-30%, tackifier: tackifying resin 5-30%, filler: water imbibition
High molecular polymer 10-40%.
A kind of stoma leakproof patch above-mentioned, the formula of plastic binder include: adhesive base according to mass percent
Bottom: high-molecular-weight propylene acid esters elastomer 20-50%, plasticizer: low molecular weight propylene acid esters elastomer 10-30%, tackifier:
Tackifying resin 10-25%, filler: absorbent polymer polymer 10-35%.
A kind of stoma leakproof patch above-mentioned, high-molecular-weight propylene acid esters elastomer is by methyl methacrylate and propylene
Acid esters block copolymerization forms.
A kind of stoma leakproof patch above-mentioned, low molecular weight propylene acid esters elastomer are acrylate block copolymer.
A kind of stoma leakproof patch above-mentioned, tackifying resin include: Petropols, terpene resin, rosin resin, and
The hydride and modified product of these three resins.
A kind of stoma leakproof patch above-mentioned, absorbent polymer polymer include: can sodium carboxymethylcellulose, crosslinking
Carboxymethyl cellulose, hydroxyethyl cellulose, sodium acrylate, xanthan gum, guar gum, Arabic gum, gelatin, one of pectin
Or several mixing.
A kind of stoma preparation method of leakproof patch, includes the following steps:
Step 1 weighs various raw materials according to the formula of plastic binder, and formula includes: adhesive according to mass percent
Substrate: high-molecular-weight propylene acid esters elastomer 10-50%, plasticizer: low molecular weight propylene acid esters elastomer 5-30%, thickening
Agent: tackifying resin 5-30%, filler: absorbent polymer polymer 10-40%；
Step 2, the temperature that mixer is arranged is between 60-80 DEG C；
Adhesive substrate is added when the temperature of mixer rises to set temperature in step 3, and plasticising is added after its softening
Agent and tackifier, three are slowly added to uniformly mixed filler after mixing, and discharge to obtain plasticity after continuing stirring 1 hour
Adhesive；
Step 4 squeezes out plastic adhesive phase, while laminating separated type material with extruder, obtains stoma leakproof patch.
A kind of preparation method of stoma leakproof patch above-mentioned, plastic adhesive phase are cyclic annular plastic adhesive sheet, ring
The plastic adhesive sheet of shape with a thickness of 0.5-5mm.
A kind of preparation method of stoma leakproof patch above-mentioned, cyclic annular plastic adhesive sheet are the plastic bonding of circular annular form
Agent piece, diameter 2-5cm.
A kind of preparation method of stoma leakproof patch above-mentioned, cyclic annular plastic adhesive sheet are that elliptical annular is plastic viscous
Mixture piece.
The invention has the beneficial effects that:
The selection of the formula of plasticity adhesive, for present thermoplastic elastomer system, the bullet of esters of acrylic acid
Property the body transparency it is more preferable, skin-friendly is also more preferable, contact skin using when hardly there is the phenomenon that allergy etc.This is matched simultaneously
When side's industrialization, processing step is simple, at low cost；
The use of the formula of plasticity adhesive, so that the integrality of leakproof patch is good, it is not in residual in stoma
Stay goo；The phenomenon that viscosity will not be too strong simultaneously, pulls stoma skin, it is easy that when replacement, removes；
Plasticity leakproof patch is in use, need to only remove separated type material layer, according to the shape size of stoma by plasticity
Adhesive patch is kneaded into consistent with stoma, is pasted onto stoma, auxiliary stoma chassis is used together, especially convex surface stoma
There is good effect on chassis to the prevention and treatment of liquid dung dermatitis.
Specific embodiment
Below in conjunction with detailed description of the invention by specific embodiments.
A kind of stoma leakproof patch, plasticity adhesive phase, the laminating release layer in plasticity adhesive phase；Plasticity
The formula of adhesive includes: adhesive substrate according to mass percent: high-molecular-weight propylene acid esters elastomer 10-50%, plasticising
Agent: low molecular weight propylene acid esters elastomer 5-30%, tackifier: tackifying resin 5-30%, filler: absorbent polymer polymerization
Object 10-40%.
High-molecular-weight propylene acid esters elastomer is formed by methyl methacrylate and acrylic ester block.
Low molecular weight propylene acid esters elastomer is acrylate block copolymer.
Tackifying resin includes: Petropols, terpene resin, the hydride and modification of rosin resin and these three resins
Product.
Absorbent polymer polymer include: can sodium carboxymethylcellulose, cross-linked carboxymethyl cellulose, hydroxy ethyl fiber
Element, sodium acrylate, xanthan gum, guar gum, Arabic gum, gelatin, the mixing of one or more of pectin.
Plastic adhesive phase is cyclic annular plastic adhesive sheet, cyclic annular plastic adhesive sheet with a thickness of 0.5-5mm.As one
Kind embodiment, cyclic annular plastic adhesive sheet are the plastic adhesive sheet of circular annular form, diameter 2-5cm；Another embodiment, it is cyclic annular
Plastic adhesive sheet is the plastic adhesive sheet of elliptical annular.
A kind of stoma preparation method of leakproof patch, includes the following steps:
Step 1 weighs various raw materials according to the formula of plastic binder；
Step 2, the temperature that mixer is arranged is between 60-80 DEG C；
Adhesive substrate is added when the temperature of mixer rises to set temperature in step 3, and plasticising is added after its softening
Agent and tackifier, three are slowly added to uniformly mixed filler after mixing, and discharge to obtain plasticity after continuing stirring 1 hour
Adhesive.
Step 4 squeezes out plastic adhesive phase, while laminating separated type material with extruder, obtains stoma leakproof patch.
Below by way of the performance of experimental verification patch of the present invention；
Embodiment 1: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 10%, plasticizer: low molecular weight propylene acid esters elastomer 30%, tackifier: tackifying resin 20%, filler: water imbibition
High molecular polymer 40%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 100g, plasticizer: low molecular weight propylene acid esters elastomer 300g, thickening
Agent: tackifying resin 200g, filler: absorbent polymer polymer 400g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 2: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 50%, plasticizer: low molecular weight propylene acid esters elastomer 5%, tackifier: tackifying resin 30%, filler: water imbibition is high
Molecularly Imprinted Polymer 15%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 500g, plasticizer: low molecular weight propylene acid esters elastomer 50g, thickening
Agent: tackifying resin 300g, filler: absorbent polymer polymer 150g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 3: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 40%, plasticizer: low molecular weight propylene acid esters elastomer 25%, tackifier: tackifying resin 5%, filler: water imbibition is high
Molecularly Imprinted Polymer 30%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 400g, plasticizer: low molecular weight propylene acid esters elastomer 250g, thickening
Agent: tackifying resin 50g, filler: absorbent polymer polymer 300g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 4: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 40%, plasticizer: low molecular weight propylene acid esters elastomer 30%, tackifier: tackifying resin 20%, filler: water imbibition
High molecular polymer 10%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 400g, plasticizer: low molecular weight propylene acid esters elastomer 250g, thickening
Agent: tackifying resin 50g, filler: absorbent polymer polymer 300g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 5: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 20%, plasticizer: low molecular weight propylene acid esters elastomer 20%, tackifier: tackifying resin 25%, filler: water imbibition
High molecular polymer 35%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 200g, plasticizer: low molecular weight propylene acid esters elastomer 200g, thickening
Agent: tackifying resin 250g, filler: absorbent polymer polymer 350g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 6: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 40%, plasticizer: low molecular weight propylene acid esters elastomer 30%, tackifier: tackifying resin 10%, filler: water imbibition
High molecular polymer 20%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 500g, plasticizer: low molecular weight propylene acid esters elastomer 300g, thickening
Agent: tackifying resin 100g, filler: absorbent polymer polymer 100g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
Embodiment 7: preparation step:
Step 1 weighs various raw materials according to formula；Formula includes: high-molecular-weight propylene acid esters bullet according to mass percent
Property body 35%, plasticizer: low molecular weight propylene acid esters elastomer 18%, tackifier: tackifying resin 22%, filler: water imbibition
High molecular polymer 25%；
The LA2330 of high-molecular-weight propylene acid esters elastomer selection import；Low molecular weight propylene acid esters elastomer is selected: into
The LA2114 of mouth；Tackifying resin is selected: terpene resin；Absorbent polymer polymer is selected: the crosslinking of Ashland company, the U.S.
Sodium carboxymethylcellulose X-CMC；
That is: high-molecular-weight propylene acid esters elastomer 350g, plasticizer: low molecular weight propylene acid esters elastomer 300g, thickening
Agent: tackifying resin 100g, filler: absorbent polymer polymer 100g.
2) temperature that mixer is arranged is between 60-80 DEG C；
3) when the temperature of mixer rises to set temperature, high-molecular-weight propylene acid esters elastomer is added, after its softening
Plasticizer is added and tackifier, three are slowly added to uniformly mixed filler after mixing, discharges after continuing stirring 1 hour
Obtain plasticity adhesive.
4) sheet material of 3mm thickness, while laminating separated type material are squeezed out with extruder, obtain stoma leakproof patch.
The sample 1-7 that embodiment 1-7 is prepared is done into following performance test:
Test one: residual tack object test；
The test of residual tack object: a sample of plasticity leakproof patch is taken, sample to be tested is placed under the test environment
12h or more cuts the test bars of wide 25mm, with organic solvent by tested steel plate wiped clean, it is ensured that test surfaces are without grease stain, dirt
Object is forbidden down by the band viscosity of test bars being entirely labelled to test steel plate with hand touching test surface after having wiped
On, it is rolled back and forth 3 times with the pressure roller of 2kg with the speed of about 60cm/min, 30min is placed under the conditions of 37 DEG C, observe tested steel
There is nonadhesive substance residual on plate, above-mentioned test repeated to other 4 samples, concrete outcome is shown in Table 1:
Table 1
Interpretation of result: the leakproof patch prepared using formula and method of the invention will not be gone out in stoma
Existing residual tack object.
Test two: integrity test；
Integrity test: tape backing sample to be tested is taken with moisture vapor transmission cup sampling ring, its quality is referred to as W1；It is 250ml in volume
50ml0.9% sodium chloride solution is put into conical flask；The sample that quality is W1 is put into conical flask, bottleneck plug seal；It will
The conical flask being sealed is put into shaking table, and shaking table temperature is set as 37 DEG C, revolving speed 20r/min；Sample is taken out after 18h, is put into baking
In case, drying weighs sample quality for 24 hours, after taking-up and is denoted as W2 under the conditions of 60 DEG C.Degree of integration=W2/W1*100%
It requires each sample at least to repeat to take five samples in test, is averaged.Specific data are shown in Table 2:
Table 2
Interpretation of result:
The leakproof patch prepared using formula and method of the invention, integrality is good, and sample 5-7 is preferable, sample
Product 7 are best.
Test three: peel strength test；
Taking width is the batten of 25mm, and sample is pasted on to the centre of stainless steel plate, the both sides of sample is made to be parallel to steel plate
Two long sides, with roller to sample adhesive portion apply pressure, with the speed of about 60cm/min along specimen length direction roll
Four times, it is made to park 10min at normal atmospheric pressure.It is suitable between the 15%-85% of full scale with force value range of readings
Dynamometry instrument, measurement is from power required for steel sheet peeling off sample, and peel angle is 180 °, peeling rate 300mm/min.It sees
Survey the active force applied at first 25mm length.Every 30mm observes direct action power, takes the average value of six readings.To in addition
4 samples repeat above-mentioned test, take 5 sample means.Peel strength the results are shown in Table 3:
Table 3
Interpretation of result:
The leakproof patch prepared using formula and method of the invention, viscosity is moderate, and it is easy that when replacement removes.
In conclusion the optimization formula of plastic binder includes: adhesive substrate according to mass percent: high molecular weight third
Olefin(e) acid ester elastomer 20-50%, plasticizer: low molecular weight propylene acid esters elastomer 10-30%, tackifier: tackifying resin 10-
25%, filler: absorbent polymer polymer 10-35%.
Optimization formula are as follows: high-molecular-weight propylene acid esters elastomer 35%, plasticizer: low molecular weight propylene acid esters elastomer
18%, tackifier: tackifying resin 22%, filler: absorbent polymer polymer 25%.
The acrylate elastomer molecular weight distribution used in plasticity adhesive compares concentration, the integrality of leakproof patch
Preferably, residual tack object will not occur in stoma；Stoma skin will not be pulled because viscosity is too strong simultaneously, more
It is easy to remove when changing；When using plasticity leakproof patch, separated type material layer is removed, it will be plastic according to the shape size of stoma
Property adhesive patch be kneaded into consistent with stoma, be pasted onto stoma, auxiliary stoma chassis is used together, to liquid dung dermatitis
Prevention and treatment have good effect.
The basic principles, main features and advantages of the invention have been shown and described above.The technical staff of the industry should
Understand, the above embodiments do not limit the invention in any form, all obtained by the way of equivalent substitution or equivalent transformation
Technical solution is fallen within the scope of protection of the present invention.
Claims (10)
1. a kind of stoma leakproof patch characterized by comprising plasticity adhesive phase, it is laminating to be bonded in the plasticity
The release layer of oxidant layer；The formula of plasticity adhesive includes: adhesive substrate according to mass percent: high-molecular-weight propylene acid esters
Elastomer 10-50%, plasticizer: low molecular weight propylene acid esters elastomer 5-30%, tackifier: tackifying resin 5-30%, filling
Agent: absorbent polymer polymer 10-40%.
2. a kind of stoma leakproof patch according to claim 1, which is characterized in that the formula of plastic binder is according to matter
Measuring percentage includes: adhesive substrate: high-molecular-weight propylene acid esters elastomer 20-50%, plasticizer: low molecular weight propylene acid esters
Elastomer 10-30%, tackifier: tackifying resin 10-25%, filler: absorbent polymer polymer 10-35%.
3. a kind of stoma leakproof patch according to claim 1, which is characterized in that the high-molecular-weight propylene acid esters bullet
Property body is formed by methyl methacrylate and acrylic ester block.
4. a kind of stoma leakproof patch according to claim 1, which is characterized in that the low molecular weight propylene acid esters bullet
Property body be acrylate block copolymer.
5. a kind of stoma leakproof patch according to claim 1, which is characterized in that the tackifying resin includes: petroleum
The hydride and modified product of resin, terpene resin, rosin resin and these three resins.
6. a kind of stoma leakproof patch according to claim 1, which is characterized in that the absorbent polymer polymer
Include: sodium carboxymethylcellulose, cross-linked carboxymethyl cellulose, hydroxyethyl cellulose, sodium acrylate, xanthan gum, guar gum, Ah
Draw primary glue, gelatin, the mixing of one or more of pectin.
7. a kind of stoma preparation method of leakproof patch, which comprises the steps of:
Step 1 weighs various raw materials according to the formula of plastic binder, and formula includes: adhesive base according to mass percent
Bottom: high-molecular-weight propylene acid esters elastomer 10-50%, plasticizer: low molecular weight propylene acid esters elastomer 5-30%, tackifier:
Tackifying resin 5-30%, filler: absorbent polymer polymer 10-40%；
Step 2, the temperature that mixer is arranged is between 60-80 DEG C；
Step 3, when the temperature of mixer rises to set temperature, be added adhesive substrate, after its softening after be added plasticizer and
Tackifier, three are slowly added to uniformly mixed filler after mixing, and discharge to obtain plasticity bonding after continuing stirring 1 hour
Agent；
Step 4 squeezes out plastic adhesive phase, while laminating separated type material with extruder, obtains stoma leakproof patch.
8. a kind of preparation method of stoma leakproof patch according to claim 7, which is characterized in that the plastic bonding
Oxidant layer is cyclic annular plastic adhesive sheet, the plastic adhesive sheet of ring-type with a thickness of 0.5-5mm.
9. a kind of preparation method of stoma leakproof patch according to claim 8, which is characterized in that the ring-type is plastic
Adhesive sheet is the plastic adhesive sheet of circular annular form, diameter 2-5cm.
10. a kind of preparation method of stoma leakproof patch according to claim 8, which is characterized in that the ring-type can
Modeling adhesive sheet is the plastic adhesive sheet of elliptical annular.
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Citations (6)
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|---|---|---|---|---|
| JPS544491A (en) * | 1977-06-08 | 1979-01-13 | Squibb & Sons Inc | Medical adhesive |
| CN102821792A (en) * | 2010-04-03 | 2012-12-12 | 罗曼两合公司 | Acrylate adhesive for use on the skin |
| CN106661410A (en) * | 2014-08-20 | 2017-05-10 | 株式会社可乐丽 | Acrylic adhesive composition and adhesive product |
| CN106714744A (en) * | 2014-08-20 | 2017-05-24 | 霍利斯特公司 | Buffer adhesive composition for skin-adhered medical products |
| CN107261186A (en) * | 2017-07-28 | 2017-10-20 | 威海洁瑞医用制品有限公司 | Suppress or absorb the hydrocolloid material and medical dressing and its preparation method of peculiar smell |
| CN109464233A (en) * | 2018-12-11 | 2019-03-15 | 振德医疗用品股份有限公司 | Incontinence of faces ostomy bag and its manufacturing method |
-
2019
- 2019-04-26 CN CN201910344642.6A patent/CN109876178A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS544491A (en) * | 1977-06-08 | 1979-01-13 | Squibb & Sons Inc | Medical adhesive |
| CN102821792A (en) * | 2010-04-03 | 2012-12-12 | 罗曼两合公司 | Acrylate adhesive for use on the skin |
| CN106661410A (en) * | 2014-08-20 | 2017-05-10 | 株式会社可乐丽 | Acrylic adhesive composition and adhesive product |
| CN106714744A (en) * | 2014-08-20 | 2017-05-24 | 霍利斯特公司 | Buffer adhesive composition for skin-adhered medical products |
| CN107261186A (en) * | 2017-07-28 | 2017-10-20 | 威海洁瑞医用制品有限公司 | Suppress or absorb the hydrocolloid material and medical dressing and its preparation method of peculiar smell |
| CN109464233A (en) * | 2018-12-11 | 2019-03-15 | 振德医疗用品股份有限公司 | Incontinence of faces ostomy bag and its manufacturing method |
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