CN109875642A - A thrombus removal device - Google Patents
A thrombus removal device Download PDFInfo
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- CN109875642A CN109875642A CN201910179411.4A CN201910179411A CN109875642A CN 109875642 A CN109875642 A CN 109875642A CN 201910179411 A CN201910179411 A CN 201910179411A CN 109875642 A CN109875642 A CN 109875642A
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Abstract
本发明公开了一种取栓装置。该取栓装置包括推送导管和自膨胀网架，推送导管包括伸缩部和与伸缩部的近端连接的硬管部，伸缩部的壁部是封闭的，自膨胀网架套设在伸缩部外，自膨胀网架的远端与伸缩部的远端固定连接，自膨胀网架的近端与硬管部固定连接，自膨胀网架包括多个径向凸起部和连接在相邻的径向凸起部之间的细径部，径向凸起部被配置为在受到径向压力后能收缩，以及在径向压力撤除后能自动伸展，伸缩部被配置为能随自膨胀网架的收缩和伸展而发生形变。
The invention discloses a thrombus removal device. The thrombectomy device includes a push catheter and a self-expanding mesh frame. The push catheter includes a telescopic part and a hard tube part connected to the proximal end of the telescopic part. The wall part of the telescopic part is closed, and the self-expanding mesh frame is sleeved outside the telescopic part. The distal end of the self-expanding grid is fixedly connected with the distal end of the telescopic portion, and the proximal end of the self-expanding grid is fixedly connected with the hard tube portion. To the small diameter portion between the raised portions, the radial raised portion is configured to be able to contract after being subjected to radial pressure, and to automatically expand after the radial pressure is removed, and the telescopic portion is configured to be able to expand with the self-expanding grid deformation by contraction and extension.
Description
Technical field
The present invention relates to interventional therapy equipment technical fields, take pin device more particularly, to one kind.
Background technique
Thrombus is that blood flow on the surface of cardiovascular system blood vessel inner face exfoliation or mend is formed by fritter.Variable
Fluid dependent form in, thrombus is by insoluble fibrin, the blood platelet of deposition, the leucocyte of accumulation and the red blood cell group fallen into
At there are the obturators such as deposit, patch, form thrombus obstruction or interrupt blood flow, so as to cause local tissue necrosis, shadow
Ring human health or even life-threatening.
When thrombus vein formation when, can also generate grievous injury.Such as common deep vein thrombosis (DVT) formation, meeting
It hinders blood backflow to heart, leads to swelling, ulcer, pain etc., thrombus also can be with blood backflow to heart, or even crosses the heart
Brain, lung, abdomen organ are reached behind splanchnocoel room.In pulmonary circulation, thrombus can become lung bolt by hindering pulmonary artery to damage
It fills in (PE).If hindering the arteries in lung, the total blood flow of lung may be seriously endangered, and then influence whole body, and cause
Low blood pressure and shock.
It is existing to take bolt device including taking bolt cylinder mould and push conduit.Bolt cylinder mould is taken to be incorporated in storage conduit.Take bolt net
Cage is set in outside push conduit.Push conduit is distally being connected with spring, in order to take the contraction and stretching, extension of bolt cylinder mould.
However, taking bolt cylinder mould before releasing in storage conduit, it usually needs seal wire is extend out to affected part.Take bolt cylinder mould
It is pushed along seal wire.However, since spring has gap, therefore be easy to stretch out from gap when seal wire protrudes into, so as to cause seal wire
It is unable to reach affected part.
In addition, seal wire can stop to take being pushed out for bolt cylinder mould.
Accordingly, it is desirable to provide a kind of new technical solution, to solve the above technical problems.
Summary of the invention
It is an object of the present invention to provide a kind of new solutions for taking pin device.
According to the first aspect of the invention, it provides one kind and takes pin device.It includes push conduit and from swollen that this, which takes pin device,
Swollen rack, the hard pipe section that the push conduit includes pars contractilis and connect with the proximal end of the pars contractilis, the wall of the pars contractilis
Portion be it is closed, the self-expanding rack is set in outside the pars contractilis, distal end and the pars contractilis of the self-expanding rack
Distal end be fixedly connected, the proximal end of the self-expanding rack is fixedly connected with the hard pipe section, the self-expanding rack include it is more
A radial protrusion portion and the small diameter part being connected between the adjacent radial protrusion portion, the radial protrusion portion are configured as
It can be shunk by after radial pressure, and can be stretched automatically after radial pressure is removed, the pars contractilis is configured to institute
State self-expanding rack contraction and stretching, extension and deformation occurs.
Optionally, the distal end of the pars contractilis is provided with cap portion, the cap portion is fixed on the remote of the push conduit
End is outer, and the cap portion has through-hole, and the through-hole is connected to the inner cavity of the push conduit.
Optionally, the cap portion is taper, spherical shape or elliposoidal.
Optionally, the self-expanding rack by the wire rod of memorizing material and the wire rod mixed weaving of developing material and
At, or it is formed by the wire rod mixed weaving of one or more memorizing materials, the gauge or diameter of wire of the memorizing material >=
0.06mm。
Optionally, the developing material includes at least one of platinum, gold, tungsten, bismuth, barium, platinumiridio, platinum-tungsten alloys,
Or the high molecular material added with above-mentioned at least one material.
Optionally, the memorizing material is Nitinol, nickel cobalt (alloy), ormolu or golden cadmium alloy.
Optionally, multiple salient points have been knitted to form on the wire rod of the self-expanding rack, the salient point is macromolecule material
Material.
Optionally, the high molecular material be nylon, polyester fiber, polyethylene terephthalate, polytetrafluoroethylene (PTFE),
Polyurethane or block polyamide.
Optionally, the material of the pars contractilis is rubber, silica gel, thermoplastic elastomer (TPE), polyether-block-polyamide or Buddhist nun
Dragon.
Optionally, the cap portion is all or part of visible under the irradiation of developing apparatus.
Optionally, the radial protrusion portion is in patty, spindle or spherical shape.
Optionally, including push conduit, storage conduit and storage conduit, the storage conduit are set in the push conduit
Outside, the storage conduit is set in outside the storage conduit, and the push conduit and the storage conduit can be led along the storage
Pipe axial movement, in the initial state, the self-expanding rack is contracted in the storage conduit；It is described from swollen when taking bolt
Swollen rack can be contracted in the storage conduit.
According to one embodiment of the disclosure, it is closed due to taking the wall portion of pars contractilis of pin device, therefore is stretched in seal wire
It is fashionable, it will not be pierced by from the side of push conduit, but be directly pierced by from the distal end of pars contractilis.In this way, the positioning of seal wire is more quasi-
Really, release and stretch can be more smooth from storage conduit for self-expanding rack.
In addition, seal wire will not stop self-expanding rack to be released from storage conduit.
By referring to the drawings to the detailed description of exemplary embodiment of the present invention, other feature of the invention and its
Advantage will become apparent.
Detailed description of the invention
It is combined in the description and the attached drawing for constituting part of specification shows the embodiment of the present invention, and even
With its explanation together principle for explaining the present invention.
Fig. 1 is the structural schematic diagram that pin device is taken according to one of the embodiment of the present disclosure.
Fig. 2 is the structural schematic diagram according to a self-expanding rack of the embodiment of the present disclosure.
Fig. 3 is the cross-sectional view of the self-expanding rack and push conduit according to the embodiment of the present disclosure.
Fig. 4-7 is the structural schematic diagram according to the self-expanding rack with salient point of the embodiment of the present disclosure.
Description of symbols:
11: cap portion；12: self-expanding rack；13: hard pipe section；14: pars contractilis；15: radial protrusion portion；16: small diameter part；17:
Store conduit；18: storage conduit；19: syringe；20: female Luer；21: push conduit；22: inner cavity；23: through-hole；24: convex
Point.
Specific embodiment
Carry out the various exemplary embodiments of detailed description of the present invention now with reference to attached drawing.It should also be noted that unless in addition having
Body explanation, the unlimited system of component and the positioned opposite of step, numerical expression and the numerical value otherwise illustrated in these embodiments is originally
The range of invention.
Be to the description only actually of at least one exemplary embodiment below it is illustrative, never as to the present invention
And its application or any restrictions used.
Technology, method and apparatus known to person of ordinary skill in the relevant may be not discussed in detail, but suitable
In the case of, the technology, method and apparatus should be considered as part of specification.
It is shown here and discuss all examples in, any occurrence should be construed as merely illustratively, without
It is as limitation.Therefore, other examples of exemplary embodiment can have different values.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi
It is defined in a attached drawing, then in subsequent attached drawing does not need that it is further discussed.
According to one embodiment of the disclosure, provides one kind and take pin device.As shown in Figure 1, it includes pushing away that this, which takes pin device,
Send conduit 21, self-expanding rack 12, storage conduit 17 and storage conduit 18.
Push conduit 21 includes pars contractilis 14 and the hard pipe section 13 connecting with the proximal end of pars contractilis 14.The wall portion of pars contractilis 14
It is closed.Pars contractilis 14 is made by elastic material.Elastic material has good elastic deformation performance, can be with self-expanding
The deformation of rack 12 and deformation occurs.
For example, the material of pars contractilis 14 is rubber, silica gel, thermoplastic elastomer (TPE), polyether-block-polyamide or nylon etc..
The elastic deformation performance of above-mentioned material, good tolerance.
Since the wall portion of pars contractilis 14 is closed, therefore when seal wire protrudes into, will not be pierced by from the side of push conduit 21,
But it is directly pierced by from the distal end of pars contractilis 14.In this way, the positioning of seal wire is more acurrate, self-expanding rack 12 is from storage conduit 17
Releasing and stretch can be more smooth.
In addition, seal wire will not stop self-expanding rack 12 to be released from storage conduit 17.
Hard pipe section 13 has the structural strength of setting, and can bend with the trend of blood vessel.Hard pipe section 13 it is hard
Degree is greater than the hardness of pars contractilis 14.For example, hard pipe section 13 is identical with outer diameter with the internal diameter of pars contractilis 14, the two is connected by binder
It is connected together, or is linked together by modes such as injection molding, hot-melt adhesive pastes.
Self-expanding rack 12 is by having multiple grid cells in array distribution.The shape of grid cell is round, oval
The shape of shape, diamond shape or other closed loops.Multiple grid cells can be identical structure, be also possible to different structures.Its
In, the grid cell of different structure links together, and can effectively improve the binding force of self-expanding rack 12 Yu thrombus.
Self-expanding rack 12 is set in outside pars contractilis 14.The fixed company in distal end of the distal end of self-expanding rack 12 and pars contractilis 14
It connects.For example, the distal end of self-expanding rack 12 is fixedly connected by binder with the distal end of pars contractilis 14；Or self-expanding rack 12
Distal end be injection-moulded in the distal end of pars contractilis 14, to form a fixed connection.
The proximal end of self-expanding rack 12 is fixedly connected with hard pipe section 13.For example, self-expanding rack 12 proximally by injection molding
Or the modes such as bonding are fixed on the distal end of hard pipe section 13.
In the disclosure, one end of the separate vascular entrance of component where distal end is.Proximal end is place component by nearby bleeding
One end of tube inlet.
As shown in Fig. 2, self-expanding rack 12 includes multiple radial protrusion portions 15 and is connected to adjacent radial protrusion portion 15
Between small diameter part 16.The radial direction i.e. perpendicular to the extending direction of push conduit 21.The outer diameter of small diameter part 16 is less than radial
Outer diameter of the lug boss 15 in extended state.Two adjacent radial protrusion portions 15 and small diameter part positioned there between 16 are surrounded and are used for
In the external accommodation space for accommodating thrombus.Thrombus is embedded in accommodation space.Outer diameter of the radial protrusion portion 15 in extended state is big
In the internal diameter of storage conduit 18.
Radial protrusion portion 15 is configured as after by radial pressure to shrink, and can be automatic after radial pressure is removed
Stretching, extension.Pars contractilis 14 is configured to contraction and stretching, extension with self-expanding rack 12 and deformation occurs.For example, stretching, extension refers to from swollen
The radial protrusion portion 15 of swollen rack 12 is fully deployed.The state is state when using.Contraction refers to that radial protrusion portion 15 is drawn
Directly, state when which is storage.
Radial pressure is from storage conduit 17 and storage conduit 18.Storage conduit 17 is set in outside push conduit 21.It pushes away
Send conduit 21 that can move along storage conduit 18.Storage conduit 18 is set in outside storage conduit 17.Push conduit 21 and storage conduit
17 can move axially along storage conduit 18.
In the initial state, self-expanding rack 12 is contracted in storage conduit 17.When being stored, 21 quilt of conduit is pushed
It pulls, so that the self-expanding rack 12 to have trailed is moved into storage conduit 17.Store the nozzle and tube wall pair of conduit 17
Radial protrusion portion 15 forms radial pressure, thus radial compression self-expanding rack 12.Finally, self-expanding rack 12 is retracted simultaneously quilt
It is accommodated in storage conduit 17.
When taking bolt, self-expanding rack 12 can be contracted in storage conduit 18.At this point, the push retraction of conduit 21 is led in storage
The distal end of pipe 18.Push conduit 21 is pulled, so that self-expanding rack 12 is mobile towards vascular entrance together with thrombus.Storage is led
The nozzle and tube wall of pipe 18 form radial pressure to radial lug boss 15, thus radial compression self-expanding rack 12.Finally, from swollen
Swollen rack 12 is retracted, and is entered in storage conduit 18 together with thrombus.
The internal diameter for storing conduit 18 is bigger than the internal diameter for storing conduit 17.Self-expanding rack 12 is compressed in storage conduit 18
Degree compared to storage conduit 17 in it is small.
The internal diameter for being also possible to store conduit 18 is greater than or equal to outer diameter of the radial protrusion portion 15 in stretching, extension.This
In the case of, self-expanding rack 12 is not compressed when being drawn into storage conduit 18.As long as storage conduit 18 can be stretched in the blood vessel
Enter, pull out.
In one example, as shown in figs. 1 and 3, the distal end of pars contractilis 14 is provided with cap portion 11.Cap portion 11 is fixed on
Outside the distal end for pushing conduit 21.For example, the proximal end in cap portion 11 forms plug.The nozzle of the distal end of plug insertion storage conduit 17
It is interior, and form a fixed connection.Cap portion 11 has through-hole 23.Through-hole 23 is connected to the inner cavity 22 of push conduit 21.Seal wire is passing through
Behind the inner cavity 22 for pushing conduit 21, it is pierced by from through-hole 23.The structural strength in cap portion 11 is high, and it is curved that this is not susceptible to pars contractilis 14
Folding.
In addition, cap portion 11 has the weight of setting, can prevent contraction flow region take pin device in the blood vessel in traveling process with
Meaning is swung.
In one example, cap portion 11 is taper, spherical shape or elliposoidal.The cap portion 11 of above-mentioned shape and the friction of thrombus
Power is small, this enables self-expanding rack 12 swimmingly to advance and pass through thrombus in the blood vessel.
In one example, cap portion 11 is all or part of visible under the irradiation of developing apparatus.For example, in the remote of cap portion 11
End setting developing material.Operator can clearly observe the position of the distal end in cap portion 11 when operating, the position
Clinical meaning is bigger.
It can be, cap portion 11 is partially provided with developing material.Developing material includes noble metal developing ring.
It is also possible that cap portion 11 is partially or fully prepared by high molecular material.It is mixed in high molecular material
The powder of the developing materials such as barium sulfate, sulfuric acid tungsten.
It is also possible to all surfaces or local surfaces in cap portion 11 coated with developing material.
In one example, self-expanding rack 12 by the wire rod of memorizing material and the yarn woven of developing material and
At, or formed by the wire rod of memorizing material and the yarn woven of high molecular material.Memorizing material include memorial alloy and
Remember high molecular material etc..Elastic deformation can occur under the effect of external force for memorizing material, can be extensive after external force is removed
Multiple original state.Memorial alloy includes for Nitinol, nickel cobalt (alloy), ormolu, golden cadmium alloy etc..Remember high molecular material
Including polynorbornene, styrene-butadiene copolymer, shape memory polyurethane etc..
Developing material is the material that can develop under radiation exposure (for example, X-ray).For example, developing material platinum, gold, tungsten,
At least one of bismuth, barium, platinumiridio, platinum-tungsten alloys, or the high molecular material added with above-mentioned at least one material.
For example, high molecular material is nylon, polyester fiber, polyethylene terephthalate, polytetrafluoroethylene (PTFE), polyurethane
Or block polyamide.Compared with metal material, the binding force of high molecular material and thrombus is stronger.
In this example embodiment, on the one hand due to the presence of memory material, self-expanding rack 12 is stretched out from storage conduit 17
When can return back to extended state, that is, form multiple radial protrusion portions 15；Another aspect developing material makes that pin device is taken to have
Bigger development area.Operator can be more easily observed the position of self-expanding rack 12.The positioning of self-expanding rack 12
It is more acurrate.
In one example, cap portion 11 is also developing material.In this way, operator can be more easily observed self-expanding net
The position of 12 distal end of frame.Cap portion 11 can more easily reach the distal end of thrombus.
In one example, radial protrusion portion 15 is in patty, spindle or spherical shape.Above-mentioned shape all has big cut
Area.This enables radial protrusion portion 15 more effectively to scrape thrombus, takes bolt excellent effect.
In other examples, self-expanding rack is formed by the wire rod mixed weaving of one or more memorizing materials.Memory
Diameter >=0.06mm of the wire rod of property material.Memorizing material itself has the function of development in the size range, that is, is setting
Determine to develop under the ray of frequency.For example, X-ray.In this way, when in use, self-expanding rack is more easily observed in operator
12 position.In this example embodiment, it does not need that other developing materials are in addition arranged.
In one example, as shown in figs. 4-7, multiple salient points 24 have been knitted to form on the wire rod of self-expanding rack 12.
Salient point 24 is high molecular material.For example, multiple salient points 24 are evenly distributed along the extending direction of wire rod.Salient point 24 is increased from swollen
The contact area of swollen rack and thrombus, and to the effect that thrombosis hooks, it is right can effectively to increase self-expanding rack 12
Thrombus arrests ability.
For example, as shown in figure 4, being provided with salient point 24 in the radial protrusion portion of self-expanding rack 12 and small diameter part.It is convex
24 outwardly convexs of point.Outwardly convex refers to that salient point 24 is directed toward outside the space that wire rod is surrounded.
For example, as shown in figure 5, being only proximally and distally provided with salient point 24 in the radial protrusion portion of self-expanding rack 12.It is convex
24 outwardly convexs of point.
For example, as shown in fig. 6, being only provided with salient point 24 in the proximal end in the radial protrusion portion of self-expanding rack 12.Salient point 24
Outwardly convex.
For example, as shown in fig. 7, being only provided with salient point 24 in the distal end in the radial protrusion portion of self-expanding rack 12.Salient point 24
Outwardly convex.
For example, high molecular material is nylon, polyester fiber, polyethylene terephthalate, polytetrafluoroethylene (PTFE), polyurethane
Or block polyamide.Above-mentioned material is easily formed salient point 24.For example, salient point 24 forms root shape structure.This structure and thrombus
Hook effect is bigger.Certainly, the protrusion direction of salient point 24 can also be inside, inwardly refers to that salient point 24 is directed toward the sky that wire rod is surrounded
In.
It is also possible to part salient point 24 inwardly, part salient point 24 is outside.
Certainly, the set-up mode of salient point 24 is not limited to the above embodiments, and those skilled in the art can be according to actual needs
It is configured.
According to another embodiment of the present disclosure, a kind of application method for taking pin device to take bolt is disclosed.This method packet
It includes:
S1, the distal end that seal wire is stretched to thrombus along blood vessel.Seal wire takes pin device for guiding.Seal wire is the used of this field
With technological means, do not elaborate herein.Since the wall portion of contraction flow region is closed, therefore the distal end of seal wire will not be from contraction flow region
Wall portion be pierced by.
S2, will take 21 sets of push conduit of pin device outside seal wire, and along seal wire will push conduit 21, storage 17 and of conduit
Storage conduit 18 protrudes into together, and reaches the proximal end of thrombus.
S3, storage conduit 17 is pushed, to be passed through thrombus.At this point, the position of the self-expanding rack 12 of contraction state with
The position of thrombus is corresponding.
S4, seal wire is extracted out from push conduit 21.
S5, will storage conduit 17 towards vascular entrance direction pull out thrombus, and be retracted to storage conduit 18 in set away from
From.At this point, self-expanding rack 12 trails, so that in multiple radial protrusion portions 15 insertion thrombus.
S6, push conduit 21 is pulled towards vascular entrance direction.At this point, thrombus is moved together with self-expanding rack 12.It pushes away
The distal end for sending conduit 21 to reach storage conduit 18.Pull on push conduit 21.Since the internal diameter of storage conduit 18 is less than radial direction
The outer diameter of lug boss 15, therefore in drawing process, the nozzle and tube wall for storing conduit 18 form radial direction to radial lug boss 15
Pressure.Radial protrusion portion 15 is shunk under the action of radial pressure, and finally enters storage conduit together with thrombus
In 18.Thrombus is temporarily stored in storage conduit 18.
S7, push conduit 21, storage conduit 17 and storage conduit 18 are pulled out together.
It is removed by aforesaid operations step thrombus.
It should be noted that as shown in Fig. 2, being provided with female Luer 20 in the proximal end of storage conduit 18.Female Luer 20
Branch connect syringe 19.Syringe 19 is used for draw blood during taking bolt.
Although some specific embodiments of the invention are described in detail by example, the skill of this field
Art personnel it should be understood that example above merely to being illustrated, the range being not intended to be limiting of the invention.The skill of this field
Art personnel are it should be understood that can without departing from the scope and spirit of the present invention modify to above embodiments.This hair
Bright range is defined by the following claims.
Claims (11)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910179411.4A CN109875642A (en) | 2019-03-11 | 2019-03-11 | A thrombus removal device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910179411.4A CN109875642A (en) | 2019-03-11 | 2019-03-11 | A thrombus removal device |
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| CN109875642A true CN109875642A (en) | 2019-06-14 |
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| CN201910179411.4A Pending CN109875642A (en) | 2019-03-11 | 2019-03-11 | A thrombus removal device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111887935A (en) * | 2020-07-29 | 2020-11-06 | 山东维心医疗器械有限公司 | Blood vessel dredging and cleaning device |
| CN112089477A (en) * | 2020-10-16 | 2020-12-18 | 上海腾复医疗科技有限公司 | Basket type thrombus removing device |
| CN112274216A (en) * | 2020-11-19 | 2021-01-29 | 上海睿触科技有限公司 | A vascular stent for safe thrombus extraction |
| CN113133804A (en) * | 2021-04-30 | 2021-07-20 | 杭州亿科医疗科技有限公司 | Thrombus-taking support |
| CN113633445A (en) * | 2021-07-09 | 2021-11-12 | 上海玮琅医疗科技有限公司 | Thrombus-taking bracket catheter |
| CN115337074A (en) * | 2021-05-14 | 2022-11-15 | 复旦大学 | A thrombectomy device for pulmonary embolism with blood flow conduction function |
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