CN109856350A - For detecting human body to the kit of Docetaxel drug effect and adverse reaction - Google Patents
For detecting human body to the kit of Docetaxel drug effect and adverse reaction Download PDFInfo
- Publication number
- CN109856350A CN109856350A CN201811617757.XA CN201811617757A CN109856350A CN 109856350 A CN109856350 A CN 109856350A CN 201811617757 A CN201811617757 A CN 201811617757A CN 109856350 A CN109856350 A CN 109856350A
- Authority
- CN
- China
- Prior art keywords
- bracket
- liquid bath
- intercommunicating pore
- kit
- bottle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 title claims abstract description 14
- 229960003668 docetaxel Drugs 0.000 title claims abstract description 14
- 230000000857 drug effect Effects 0.000 title claims abstract description 13
- 206010067484 Adverse reaction Diseases 0.000 title claims abstract description 12
- 230000006838 adverse reaction Effects 0.000 title claims abstract description 12
- 239000007788 liquid Substances 0.000 claims abstract description 46
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 41
- 239000011148 porous material Substances 0.000 claims abstract description 17
- 238000007789 sealing Methods 0.000 claims description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 238000003745 diagnosis Methods 0.000 abstract description 2
- 238000005070 sampling Methods 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 4
- 238000001514 detection method Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000005213 imbibition Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses for detecting human body to the kit of Docetaxel drug effect and adverse reaction, external diagnosis reagent case field is related generally to.Including reagent bottle and bracket, the reagent bottle is equipped with the bottle cap being connected through a screw thread in bottle mouth position, the top of the bottle cap is provided with pipe interface, intercommunicating pore is equipped in the middle part of the pipe interface, on the inside of the top of the intercommunicating pore connecting pipeline interface and bottle cap, the bracket is the tubular structure arranged vertically, the stent outer is provided with far from pinching screw side and takes liquid bath, the position for taking liquid bath to be positioned close to cantilever tip, it is described that liquid bath channel opening end is taken to arrange upwards, it is described that the connection of liquid bath bottom end is taken to be connected by cross over pipe with intercommunicating pore, the cross over pipe is provided with balance pipe close to one end of intercommunicating pore.The beneficial effects of the present invention are: liquid level and liquid taking port can be made to remain closer distance when carrying out reagent sampling.
Description
Technical field
The present invention relates to external diagnosis reagent case field, detection human body is particularly used for Docetaxel drug effect and bad
The kit of reaction.
Background technique
Docetaxel medicine is the common drug of cancer chemotherapy, not by the physiological reaction of patient in patient's early stage medication
Patient can be clearly judged to Docetaxel drug effect and adverse reaction real reaction, and many people will appear in various degree after medication
Reaction, be all to be checked using round pcr now, present detection device is mostly semiautomatic equipment, needs to carry out
Artificial sample-adding and incubation, the reagent bottle in conventional reagents box are all deep mouth bottles, using liquid-transfering gun carry out using when early stage
Reagent bottle directly can be placed on desktop to use up, with using amount of reagent to reduce, in order to can be reduced disposable sample-adding syringe needle
Hang liquid measure, need on the other hand take reagent bottle make its inclination, allow liquid level reach reagent bottleneck near, make one naked eyes it can be seen that liquid level and
Imbibition situation operates complex when sample size is more, influences detection efficiency.
Summary of the invention
The purpose of the present invention is to provide a kind of to be used to detect human body to Docetaxel drug effect based on digital pcr technology
And the kit of adverse reaction, it can make liquid level and liquid taking port remain closer distance when carrying out reagent sampling.
The present invention to achieve the above object, is achieved through the following technical solutions:
It is described for detecting human body to the kit of Docetaxel drug effect and adverse reaction, including reagent bottle and bracket
Reagent bottle is equipped with the bottle cap being connected through a screw thread in bottle mouth position, and the top of the bottle cap is provided with pipe interface, and the pipeline connects
Intercommunicating pore is equipped in the middle part of mouthful, the top of the intercommunicating pore connecting pipeline interface and bottle cap inside, the bracket are arranged vertically
Tubular structure, the stent outer is provided with far from pinching screw side and takes liquid bath, described that liquid bath is taken to be positioned close to top of support
The position at end, it is described that liquid bath channel opening end is taken to arrange upwards, it is described that the connection of liquid bath bottom end is taken to be connected by cross over pipe with intercommunicating pore
Logical, the cross over pipe is provided with balance pipe close to one end of intercommunicating pore.
The support height is higher than reagent bottle height.
Pinching screw is connected through a screw thread in the one side wall of the bracket, the pinching screw setting is in bracket close to top
Portion position.
The pinching screw rotates coaxially in bracket inner opposite end and screw and is connected with compact heap.
It is described that liquid bath is taken to be equipped with sealing plate close to bracket side, it is described that liquid bath overthe openings is taken to slidably connect cover board.
The prior art is compared, the beneficial effects of the present invention are:
After bottle cap and reagent bottle locking, reagent bottle is stood upside down in insertion bracket when use, pass through rotation housing screw
Rotation section fixes compact heap by reagent bottle and bracket, keeps the liquid level in reagent bottle concordant with liquid bath top is taken when fixed, makes
Liquid process must be taken to remain can be with one-handed performance, and naked eyes can significantly observe shape when disposable sample needle is loaded
State reduces because of the outer wall hanging liquid of sample needle caused by operation or causes liquid level too low so that one because liquid level situation can not be observed
Influence of the secondary property sample needle sucking air to testing accuracy.
Detailed description of the invention
Attached drawing 1 is the forward sight direction structure stereoscopic schematic diagram of cover board opening state of the invention.
Attached drawing 2 is the backsight direction structure stereoscopic schematic diagram of cover board opening state of the invention.
Attached drawing 3 is the forward sight direction structure stereoscopic schematic diagram of cover board closed state of the invention.
Attached drawing 4 is structure sectional view of the invention.
Label shown in attached drawing:
1, reagent bottle；2, bracket；3, pipe interface；4, intercommunicating pore；5, pinching screw；6, compact heap；7, rotation section；8, it takes
Liquid bath；9, sealing plate；10, cover board；11, cross over pipe；12, balance pipe；13, bottle cap.
Specific embodiment
Present invention will be further explained below with reference to specific examples.It should be understood that the present embodiment be merely to illustrate the present invention and
It is not used in and limits the scope of the invention.In addition, it should also be understood that, after reading the content taught by the present invention, those skilled in the art
The present invention can be made various changes or modifications, such equivalent forms equally fall within range defined herein.
Embodiment is as follows:
For detecting human body to the kit of Docetaxel drug effect and adverse reaction, including reagent bottle 1 and bracket 2, institute
1 mouthful of the reagent bottle sealing film for being equipped with aluminium envelope is stated, when in use opens the sealing film that aluminium seals, 1 mouthful of outside of the reagent bottle
For helicitic texture, the reagent bottle 1 is equipped with bottle cap 13 in bottle mouth position, is equipped on the inside of the bottle cap 13 and matches with external thread of bottleneck
Internal screw thread, the apical lateral of the bottle cap 13 is provided with pipe interface 3, intercommunicating pore 4, institute is equipped in the middle part of the pipe interface 3
13 inside of top and bottle cap of 4 connecting pipeline interface 3 of intercommunicating pore is stated, the bracket 2 is the rectangular cross-sectional tubulose arranged vertically
Structure, 2 height of bracket are higher than 1 height of reagent bottle, have been connected through a screw thread pinching screw 5 in the one side wall of the bracket 2,
The pinching screw 5 is arranged in bracket 2 close to top position, and the pinching screw 5 coaxially turns in 2 inner opposite end of bracket with screw
It is dynamic to be connected with compact heap 6, pinching screw 5 is reduced by compact heap 6 and is contacted with the direct of reagent bottle 1, pinching screw 5 is eliminated and is turning
When dynamic and the friction of reagent bottle 1, the pinching screw 5 are provided with rotation section 7, the rotation outside in 2 lateral ends of bracket
The strip projected parts for being parallel to 5 axis of pinching screw are set, frictional force when rotation can be increased, 2 outside of bracket is separate
5 side of pinching screw, which is provided with, takes liquid bath 8, and the position for taking liquid bath 8 to be positioned close to 2 top of bracket is described to take 8 slot of liquid bath
Open end is arranged upwards, described that 8 bottom section of liquid bath is taken to be less than opening section.
It is described that liquid bath 8 is taken to be equipped with sealing plate 9 close to 2 side of bracket, it is described to take 8 overthe openings of liquid bath perpendicular to 2 side wall of bracket
Slidably connect cover board 10, the cover board 10 is c-type structure, and 10 both ends of cover board are provided with limit plate, the limit plate with
8 side view of liquid bath is taken to be adapted, the sealing plate 9 and cover board 10 can will take the opening of liquid bath 8 to be completely covered by, and reduce reagent volatilization
With the pollution of outer bound pair reagent.It is described that the connection of 8 bottom end of liquid bath is taken to be connected by cross over pipe 11 with intercommunicating pore 4, the cross over pipe
11 are provided with balance pipe 12 close to one end of intercommunicating pore 4, and the open end of the balance pipe 12 should be put in the position covered higher than reagent bottle 1
It sets, for balancing the pressure in reagent bottle 1.
After bottle cap 13 and reagent bottle 1 are locked, reagent bottle 1 is stood upside down in insertion bracket 2 when use, pass through rotation and compress spiral shell
The rotation section 7 of nail keeps compact heap 6 that reagent bottle 1 and bracket 2 is fixed, and the liquid level in reagent bottle 1 is made when fixed and liquid bath 8 is taken to push up
Hold level with both hands neat, the nozzle of balance pipe 12 should be higher than that the liquid level in reagent bottle 1, the reagent in reagent bottle 1 can by communicating pipe into
Enter to take liquid bath 8, takes liquid bath 8 to carry out taking liquid by what is be arranged on bracket 2 when use, movable cover plate 10 will take liquid bath when not in use
8 opening is completely covered by reduction cross contamination.
Claims (5)
1. for detecting human body to the kit of Docetaxel drug effect and adverse reaction, it is characterised in that: including reagent bottle (1)
With bracket (2), the reagent bottle (1) is equipped with the bottle cap being connected through a screw thread in bottle mouth position, and the top of the bottle cap is provided with pipe
Road interface (3), pipe interface (3) middle part are equipped with intercommunicating pore (4), the top of intercommunicating pore (4) the connecting pipeline interface (3)
With on the inside of bottle cap, the bracket (2) is the tubular structure arranged vertically, far from pinching screw (5) side on the outside of the bracket (2)
It is provided with and takes liquid bath (8), the position for taking liquid bath (8) to be positioned close to bracket (2) top is described to take liquid bath (8) channel opening
End arranges that described that the connection of liquid bath (8) bottom end is taken to be connected by cross over pipe (11) with intercommunicating pore, the cross over pipe (11) is leaned on upwards
One end of nearly intercommunicating pore is provided with balance pipe (12).
2. according to claim 1 for detecting human body to the kit of Docetaxel drug effect and adverse reaction, feature
Be: the bracket (2) is highly higher than reagent bottle (1) height.
3. according to claim 1 for detecting human body to the kit of Docetaxel drug effect and adverse reaction, feature
It is: has been connected through a screw thread pinching screw (5) in the one side wall of the bracket (2), the pinching screw (5) is arranged in bracket
(2) close to top position.
4. according to claim 1 for detecting human body to the kit of Docetaxel drug effect and adverse reaction, feature
Be: the pinching screw (5) rotates coaxially in bracket (2) inner opposite end and screw and is connected with compact heap (6).
5. according to claim 1 for detecting human body to the kit of Docetaxel drug effect and adverse reaction, feature
It is: it is described that liquid bath (8) is taken to be equipped with sealing plate (9) close to bracket (2) side, it is described that liquid bath (8) overthe openings is taken to slidably connect
Cover board (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811617757.XA CN109856350A (en) | 2018-12-28 | 2018-12-28 | For detecting human body to the kit of Docetaxel drug effect and adverse reaction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811617757.XA CN109856350A (en) | 2018-12-28 | 2018-12-28 | For detecting human body to the kit of Docetaxel drug effect and adverse reaction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109856350A true CN109856350A (en) | 2019-06-07 |
Family
ID=66892847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811617757.XA Pending CN109856350A (en) | 2018-12-28 | 2018-12-28 | For detecting human body to the kit of Docetaxel drug effect and adverse reaction |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109856350A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110646387A (en) * | 2019-09-17 | 2020-01-03 | 苏州康吉诊断试剂有限公司 | Kit for flow-type fluorescence detection method |
| CN114317240A (en) * | 2021-12-21 | 2022-04-12 | 深圳清华大学研究院 | Fixing device, liquid changing device and sequencer |
Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806357A (en) * | 1987-11-25 | 1989-02-21 | The Regents Of The University Of California | Apparatus and method for encapsulating seeds and the like |
| CN2593168Y (en) * | 2003-01-06 | 2003-12-17 | 陈门军 | Equi-liquid-level liquid quantitative metering apparatus |
| CN2602771Y (en) * | 2003-02-20 | 2004-02-11 | 济南市第四人民医院 | Disposable side-hole type transfusion device capable of preventing residue, particle and pollution |
| CN200995140Y (en) * | 2006-12-29 | 2007-12-26 | 浙江大学 | Self-flowing sealed liquid takeout device |
| US20080279723A1 (en) * | 2007-05-11 | 2008-11-13 | Peter Miller | Apparatus for quality control analysis of an on-site prepared pharmaceutical product |
| CN201867318U (en) * | 2010-11-19 | 2011-06-15 | 邵永生 | Flip liquid sampler |
| CN103091256A (en) * | 2013-01-16 | 2013-05-08 | 珠海森龙生物科技有限公司 | Sealing reagent supply system |
| CN203274835U (en) * | 2013-04-24 | 2013-11-06 | 肇庆理士电源技术有限公司 | Lead-acid storage battery gas collection device |
| CN203436561U (en) * | 2013-09-22 | 2014-02-19 | 周德玉 | Sterile solution storage machine for medical nursing |
| CN104004851A (en) * | 2014-06-16 | 2014-08-27 | 广州凯普生物科技有限公司 | Typing detection kit for Candida albicans |
| CN203803522U (en) * | 2014-04-30 | 2014-09-03 | 中国矿业大学 | Automatic and continuous quantitative liquid adding instrument |
| CN205079968U (en) * | 2015-10-15 | 2016-03-09 | 江苏焕鑫新材料股份有限公司 | Hand -held type liquid transfer device |
| CN105784953A (en) * | 2016-05-25 | 2016-07-20 | 延边大学 | Full-automatic dissolvability testing device of flowing cell |
| CN206152770U (en) * | 2016-08-30 | 2017-05-10 | 济南科琳宝环境科技有限公司 | Invert constant liquid level liquid feeding device |
| CN106860949A (en) * | 2017-02-28 | 2017-06-20 | 朱保群 | Automatic liquid-stopping transfusion apparatus |
| CN206969401U (en) * | 2017-05-17 | 2018-02-06 | 上海集承环保技术有限公司 | A kind of overflow recovery device |
| CN107803377A (en) * | 2017-10-13 | 2018-03-16 | 义乌市绿美生物科技有限公司 | A kind of chemical reagent shunting device |
| US20180229241A1 (en) * | 2017-02-10 | 2018-08-16 | Lonza Ltd. | Cell Culture System And Method |
| CN209606422U (en) * | 2018-12-28 | 2019-11-08 | 济南市第四人民医院 | For detecting human body to the kit of Docetaxel drug effect and adverse reaction |
-
2018
- 2018-12-28 CN CN201811617757.XA patent/CN109856350A/en active Pending
Patent Citations (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806357A (en) * | 1987-11-25 | 1989-02-21 | The Regents Of The University Of California | Apparatus and method for encapsulating seeds and the like |
| CN2593168Y (en) * | 2003-01-06 | 2003-12-17 | 陈门军 | Equi-liquid-level liquid quantitative metering apparatus |
| CN2602771Y (en) * | 2003-02-20 | 2004-02-11 | 济南市第四人民医院 | Disposable side-hole type transfusion device capable of preventing residue, particle and pollution |
| CN200995140Y (en) * | 2006-12-29 | 2007-12-26 | 浙江大学 | Self-flowing sealed liquid takeout device |
| US20080279723A1 (en) * | 2007-05-11 | 2008-11-13 | Peter Miller | Apparatus for quality control analysis of an on-site prepared pharmaceutical product |
| CN201867318U (en) * | 2010-11-19 | 2011-06-15 | 邵永生 | Flip liquid sampler |
| CN103091256A (en) * | 2013-01-16 | 2013-05-08 | 珠海森龙生物科技有限公司 | Sealing reagent supply system |
| CN203274835U (en) * | 2013-04-24 | 2013-11-06 | 肇庆理士电源技术有限公司 | Lead-acid storage battery gas collection device |
| CN203436561U (en) * | 2013-09-22 | 2014-02-19 | 周德玉 | Sterile solution storage machine for medical nursing |
| CN203803522U (en) * | 2014-04-30 | 2014-09-03 | 中国矿业大学 | Automatic and continuous quantitative liquid adding instrument |
| CN104004851A (en) * | 2014-06-16 | 2014-08-27 | 广州凯普生物科技有限公司 | Typing detection kit for Candida albicans |
| CN205079968U (en) * | 2015-10-15 | 2016-03-09 | 江苏焕鑫新材料股份有限公司 | Hand -held type liquid transfer device |
| CN105784953A (en) * | 2016-05-25 | 2016-07-20 | 延边大学 | Full-automatic dissolvability testing device of flowing cell |
| CN206152770U (en) * | 2016-08-30 | 2017-05-10 | 济南科琳宝环境科技有限公司 | Invert constant liquid level liquid feeding device |
| US20180229241A1 (en) * | 2017-02-10 | 2018-08-16 | Lonza Ltd. | Cell Culture System And Method |
| CN106860949A (en) * | 2017-02-28 | 2017-06-20 | 朱保群 | Automatic liquid-stopping transfusion apparatus |
| CN206969401U (en) * | 2017-05-17 | 2018-02-06 | 上海集承环保技术有限公司 | A kind of overflow recovery device |
| CN107803377A (en) * | 2017-10-13 | 2018-03-16 | 义乌市绿美生物科技有限公司 | A kind of chemical reagent shunting device |
| CN209606422U (en) * | 2018-12-28 | 2019-11-08 | 济南市第四人民医院 | For detecting human body to the kit of Docetaxel drug effect and adverse reaction |
Non-Patent Citations (4)
| Title |
|---|
| RICHARD L.SMITH: "Small-scale,hydrogen-oxidizing-denitrifying bioreactor for treatment of nitrate-contaminated drinking water", 《WATER RESEARCH》 * |
| ZHANG XINING: "New Active Online Balancing Method for Grinding Wheel Using Liquid Injection and Free Dripping", 《JOURNAL OF VIBRATION AND ACOUSTICS》 * |
| 朱文军 等: "《学科教学详解 初中物理》", 31 July 2015, 湖南教育出版社 * |
| 郭小红 等: "大输液设备清洗后清洁度验证", 《农垦医学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110646387A (en) * | 2019-09-17 | 2020-01-03 | 苏州康吉诊断试剂有限公司 | Kit for flow-type fluorescence detection method |
| CN114317240A (en) * | 2021-12-21 | 2022-04-12 | 深圳清华大学研究院 | Fixing device, liquid changing device and sequencer |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
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Application publication date: 20190607 |