CN109771315A - A kind of disposable hand-wrist bones gel of environment-friendly type and preparation method thereof - Google Patents
A kind of disposable hand-wrist bones gel of environment-friendly type and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to hygiene article sectors, and in particular to a kind of disposable hand-wrist bones gel of environment-friendly type and preparation method thereof.A kind of disposable hand-wrist bones gel of environment-friendly type, including following components: fungicide, thickener, the polyalcohol that carbon atom number is 2~6, pH adjusting agent, loquat extract, water；Wherein, the fungicide is selected from least one of chela polyguanidine, polyhexamethylene guanide, poly hexamethylene biguanide.The disposable hand-wrist bones gel of environment-friendly type of the invention has the effect of that quick sterilization, environmental protection are non-stimulated, takees good care of both hands.And the disinfecting gel has good moisture retention, can be realized long-term water lock and prevent moisture from evaporating by the multicomponents such as thickener, polyalcohol synergistic effect.
Description
Technical field
The present invention relates to hygiene article sectors, and in particular to a kind of disposable hand-wrist bones gel of environment-friendly type and preparation method thereof.
Background technique
For hand, not only presence often occupies bacterium but also there are tabernacle bacterium.Often occupying bacterium is that one kind can be from most of human skin point
The microorganism come is separated out, is the bacterium that lives away from home on skin persistently, intrinsic, is distributed in each surface layer of skin, is rubbed by mechanical
Wiping generally is not easy to be removed.Tabernacle bacterium then resides in skin surface, is easy for being removed in conventional hand washing process micro-
Biology.It is achieved with, and can be mutually passed by palmistry when tabernacle bacterium is by directly contacting patient or contaminated object at any time
It broadcasts, it is closely related with nosocomial infection.The microorganism for leading to infection includes gram-positive bacteria (such as staphylococcus aureus, resistance to first
Oxygen XiLin staphylococcus aureus, enterococcus, staphylococcus epidermis), Gram-negative bacteria (such as Escherichia coli, Pseudomonas aeruginosa, Bao
Family name's acinetobacter calcoaceticus, serratia marcescens), form bacterium (such as clostridium difficile, Bacillus cercus), the fungi of gemma
(such as Candida albicans), viral (such as hepatitis type B virus, human immunodeficiency virus, influenza virus).
Various hand-wrist bones products emerge one after another in the market, many kinds of, according to domestic classification, there are mainly three types of
Type, including solution-type, foam type and gel-type.Solution-type hand disinfectant is easiest to realization, almost all of disinfectant
The shortcomings that weak solution state can be made, but be easy splash and drippage, limits its use, some solution-type disinfectants make
Used time needs to impregnate for a long time, time-consuming and laborious.Foam type hand disinfectant can be smeared uniformly, and be not easy to drip, easy to use,
But preparation process is complicated, higher cost.A kind of disposable hand disinfectant that gel-type disinfectant rises after being, does not need after disinfection
It is rinsed with water, eliminates the limitation of water source and towel, since its tentacle can obtain, convenient and efficient, safe and effective, increasingly by people
Especially medical worker favor.Disinfecting gel mainly consists of three parts, including gel-type vehicle, effective component and auxiliary agent.
Gel-type vehicle is also thickener, and effect is the viscous pasty state for becoming system between solid and liquid.Effective component is that have to kill
The substance of bacterium effect, can effectively remove microorganism, inhibit microbial reproduction.Auxiliary agent then includes buffer, moisturizer, skin care
Agent, flavouring agent etc., this is also a big advantage of gel-type hand disinfectant.But gel is remote in terms of sterilization, water retention property at present
It is not able to satisfy the demand of people.
Summary of the invention
In order to solve the above-mentioned technical problem, it is solidifying to provide a kind of disposable hand-wrist bones of environment-friendly type for the first aspect of the invention
Glue, including following components: fungicide, thickener, the polyalcohol that carbon atom number is 2~6, pH adjusting agent, loquat extract, water；
Wherein, the fungicide is selected from least one of chela polyguanidine, polyhexamethylene guanide, poly hexamethylene biguanide.
Including following components as a kind of perferred technical scheme, by weight percentage: fungicide 0.1~1% increases
Thick dose 0.1~1%, the polyalcohol 0.01~4% that carbon atom number is 2~6, pH adjusting agent 0.01~0.2%, loquat extract
0.01~1%, water surplus.
As a kind of perferred technical scheme, the fungicide is chela polyguanidine.
As a kind of perferred technical scheme, the thickener is Carbomer thickener and/or cellulose thickener.
As a kind of perferred technical scheme, the thickener is Carbomer thickener.
As a kind of perferred technical scheme, the polyalcohol that the carbon atom number is 2~6 is selected from ethylene glycol, propylene glycol, fourth
At least one of glycol, glycerol, erythrite, xylitol, D-glucitol, inositol.
As a kind of perferred technical scheme, the polyalcohol that the carbon atom number is 2~6 is propylene glycol, glycerol, butanediol
Mixture.
As a kind of perferred technical scheme, the weight hundred of the carbon atom number is 2~6 polyalcohol and loquat extract
Dividing the sum of ratio is 0.1~4%.
As a kind of perferred technical scheme, by weight percentage, the gel component further includes auxiliary agent 0~3%.
The second aspect of the invention provides the preparation method of the gel, comprising the following steps:
(1) thickener is added to the water, stands 30~50 hours；
(2) loquat extract, the polyalcohol that carbon atom number is 2~6 are added in step (1) resulting solution；
(3) into step (2), gained mixed liquor addition fungicide is stirred；
(4) stir evenly to pH adjusting agent is added in gained mixed solution in step (3), be made gel to get.
The utility model has the advantages that the disposable hand-wrist bones gel of environment-friendly type of the invention, has quick sterilization, environmentally friendly non-stimulated, care pair
The effect of hand.And the disinfecting gel has good moisture retention by the multicomponents such as thickener, polyalcohol synergistic effect,
It can be realized long-term water lock and prevent moisture from evaporating.
Specific embodiment
For the purpose of following detailed description, it should be understood that the present invention can be used various substitutions variation and step it is suitable
Sequence, unless specifically stated on the contrary.In addition, being indicated in the case where in addition in any operational instances or otherwise pointing out
Such as all numbers of the amount of ingredient used in description and claims should be understood in all cases by term
" about " it modifies.Therefore, unless indicated to the contrary, the numerical parameter otherwise illustrated in the following description and appended dependent claims is root
The approximation changed according to the expected performance of the invention to be obtained.It is at least not intended to for the applicable of doctrine of equivalents being limited in
In the scope of the claims, each numerical parameter should at least be given up according to the number of the effective digital of report and by the way that application is common
Enter technology to explain.
To solve the above-mentioned problems, the present invention provides a kind of disposable hand-wrist bones gels of environment-friendly type, including following components: killing
Microbial inoculum, thickener, the polyalcohol that carbon atom number is 2~6, pH adjusting agent, loquat extract, water；
Wherein, the fungicide is selected from least one of chela polyguanidine, polyhexamethylene guanide, poly hexamethylene biguanide.
As a preferred embodiment, by weight percentage, including following components: fungicide 0.1~1% increases
Thick dose 0.1~1%, the polyalcohol 0.01~4% that carbon atom number is 2~6, pH adjusting agent 0.01~0.2%, loquat extract
0.01~1%, water surplus.
As a preferred embodiment, by weight percentage, including following components: fungicide 0.5%, thickener
0.6%, carbon atom number be 2~6 polyalcohol 2%, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
Fungicide
As an implementation, the antibacterial agent is in chela polyguanidine, polyhexamethylene guanide, poly hexamethylene biguanide
It is at least one.
In the application, the chela polyguanidine is called akacid, including the own guanidine of polycyclic (CAS:57028-96-3) and poly- [2- (2-
Ethyoxyl)-ethoxy ethyl ester] two kinds of ingredients of guanidine (CAS:374572-91-5), average degree of polymerization is between 4 to 5 units.
The backbone molecule amount of chela polyguanidine described herein is 1200 or so, huge due to backbone molecule amount, is affected
The arrangement of the outer-shell electron cloud of pendant atom, so that side chain outer-shell electron has very strong activity, when chela polyguanidine is acted on,
Between multiple chela polyguanidine molecules under the active influence of side chain outer-shell electron, it will form between molecule and molecule intermolecular
Multiple chela polyguanidine molecules are chained up by power --- Van der Waals force by Van der Waals force, antimicrobial surface formed one layer it is fine and close
Film, this film can tightly wrap harmful microorganism for a long time, block its channel for carrying out vital movement, change its internal penetration
Pressure, bursts its cell membrane, is killed.Entire sterilization, antibacterial process are not made with the intracorporal any plasmid of microorganism
With, do not form any new substance, be not present any chemical reaction, be sterilized by way of the film package of pure physics,
It is antibacterial.
The polyhexamethylene guanide and poly hexamethylene biguanide are all polyguanidine class high molecular polymer, can be produced in aqueous solution
Strong electropositive is contained in raw ionization, its hydrophilic group part, can adsorb usually in electronegative all kinds of bacteriums, virus, enter
Cell membrane inhibits the synthesis of film lactones plastid, causes thallus apoptosis, reach bactericidal effect.
As a preferred embodiment, the fungicide is chela polyguanidine.
The chela polyguanidine purchase is in Austrian GHB technology trade and uses Co., Ltd.
Thickener
As a preferred embodiment, the thickener is Carbomer thickener and/or cellulose thickener.
As the example of carbomer thickener, including but not limited to Carbopol 941, Acritamer 940, Carbopol NF, card
Wave nurse 2020 etc.；
As the example of cellulose family plasticizer, including but not limited to hydroxypropyl cellulose, hydroxyethyl cellulose, hydroxypropyl
Methylcellulose, methylcellulose etc.；
As a preferred embodiment, the thickener is Carbomer thickener.
Preferably, the thickener is Carbopol 941.
The polyalcohol that carbon atom number is 2~6
As a preferred embodiment, the polyalcohol that the carbon atom number is 2~6 is selected from ethylene glycol, propylene glycol, fourth
At least one of glycol, glycerol, erythrite, xylitol, D-glucitol, inositol.
As a preferred embodiment, the polyalcohol that the carbon atom number is 2~6 is propylene glycol, glycerol, butanediol
Mixture.
Preferably, the weight part ratio of the propylene glycol, glycerol and butanediol is 1:(2~4): (0.5~1).
It is highly preferred that the weight part ratio of the propylene glycol, glycerol and butanediol is 1:4:1.
PH adjusting agent
As a preferred embodiment, the pH adjusting agent is selected from lactic acid, citric acid, malic acid, triethanolamine, hydrogen
At least one of sodium oxide molybdena.
Preferably, the pH adjusting agent is triethanolamine.
Loquat extract
As a preferred embodiment, the loquat extract is loquat berry extract.
Loquat-Shaped Cake is the fruit of rosaceous plant loquat.Latin plant animal mineral name: Eriobotrya japonica
(Thunb.)Lindl.[Mespilus japonica Thunb.]。
Loquat is spherical or oblong, diameter 3-5cm, yellow or crocus；1-5, seed, spherical or oblate spheroid,
Diameter 1-1.5cm, brown are bright.
Chemical component fruit (cryptoxanthin) containing kryptoxanthin, new-beta-carotene (neo- β-carotene) and
DL-LACTIC ACID (DL-lactic acid) and tartaric acid (tartaric acid), immature fruit contain inverted sugar, sucrose
(sucrose), free citric acid (citric acid), malic acid (malic acid), ripening fruits contain inverted sugar, sucrose, apple
Tartaric acid.Furthermore still contain pectin (pectin) 3.3%, pentose, malic acid, succinic acid (succinic acid), oxidizing ferment, shallow lake
Powder enzyme, emulsin and invertase.
Property is sweet, sour；It is cool；It is nontoxic.
The loquat extract extracting method: the ionized water that loquat is put into 10 times of parts by weight is boiled 60 points in
Clock is cooled to 35 DEG C of holdings 60 minutes or more, filters out impurity, vacuum and low temperature is condensed into loquat extract.
The applicant has been surprisingly found that, after loquat extract is added, can be improved the water retention property of gel.The possible reason is
One side loquat extract small molecular substance enters between gel segment and the hole of segment, reduces the fortune between segment
It is dynamic, so as to lock more hydrones, increase the water retention property of gel.On the other hand, the active group in loquat extract
Group, promotes the polymerization of gel, so that gel is had the hole of more perfect structure and more comparatively dense, due to the siphon of hole
Effect, improves the water retention property of gel.
As a preferred embodiment, the weight hundred of polyalcohol and loquat extract that the carbon atom number is 2~6
Dividing the sum of ratio is 0.1~4%.
Preferably, the sum of the carbon atom number is 2~6 polyalcohol and the weight percent of loquat extract be 1~
3%.
It is highly preferred that the sum of polyalcohol and the weight percent of loquat extract that the carbon atom number is 2~6 are
1.5%.
When the sum of the polyalcohol and loquat extract weight percentage that carbon atom number is 2~6 are 0.1~4%, realizing
While gel water retention property, the water absorbing properties of gel can be improved.The applicant conjecture when carbon atom number be 2~6 it is polynary
It when the sum of alcohol and loquat extract weight percentage are controlled in a certain range, accommodate the gel network structure to be formed can largely
Free water.If the swelling of gel and water absorbing properties numerical value are relatively low less than 0.05%；Company if more than 4%, between gel segment
It connects relatively closely, the volume-diminished of Free water can be accommodated, cause the amount for entering Free water in gel to reduce, and then lead to water-setting
Swelling behavior, the water absorbing properties of glue reduce.
Suitable gel network structure makes fungicide be uniformly dispersed wherein simultaneously, can be in skin surface using rear fungicide
Stablize quick release.
As a preferred embodiment, by weight percentage, the gel component further includes auxiliary agent 0~3%.
The auxiliary agent can make disinfecting gel have whitening, anti-aging effect and be sustained out soft pure and fresh fragrance, stay
Fragrant lasting, fragrance is pure.
The auxiliary agent includes that Rosmarinus officinalis extract, Herba Lysimachiae foenumgraeci extract, olive extract, green-tea extract, peppermint mention
Take object, licorice, chrysanthemum extract, rose extract, jasmine flower extract, tea flower extract.
No. CAS of the Rosmarinus officinalis extract is 84604-14-8, and No. CAS of the Herba Lysimachiae foenumgraeci extract is 91722-
69-9, No. CAS of the green-tea extract are 84650-60-2, and No. CAS of the mint extract is 84082-70-2, described
No. CAS of licorice is 97676-23-8, and No. CAS of the green-tea extract is 84650-60-2.
The second aspect of the present invention provides the preparation method of the gel, comprising the following steps:
(1) thickener is added to the water, stands 30~50 hours；
(2) loquat extract, the polyalcohol that carbon atom number is 2~6 are added in step (1) resulting solution；
(3) into step (2), gained mixed liquor addition fungicide is stirred；
(4) stir evenly to pH adjusting agent is added in gained mixed solution in step (3), be made gel to get.
The present invention is specifically described below by embodiment.It is necessarily pointed out that following embodiment is only used
In the invention will be further described, it should not be understood as limiting the scope of the invention, professional and technical personnel in the field
The some nonessential modifications and adaptations made according to the content of aforementioned present invention, still fall within protection scope of the present invention.
In addition, if without other explanations, it is raw materials used to be all commercially available.
Embodiment
Embodiment 1
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.1%, thickening
Agent 0.1%, the polyalcohol 0.01% that carbon atom number is 2~6, pH adjusting agent 0.01%, loquat extract 1%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:2:0.5.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, comprising the following steps:
(1) thickener is added to the water, stands 40 hours；
(2) loquat extract, the polyalcohol that carbon atom number is 2~6 are added in step (1) resulting solution；
(3) into step (2), gained mixed liquor addition fungicide is stirred；
(4) stir evenly to pH adjusting agent is added in gained mixed solution in step (3), be made gel to get.
Embodiment 2
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 1%, thickener
1%, carbon atom number be 2~6 polyalcohol 4%, pH adjusting agent 0.2%, loquat extract 0.01%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:2:0.5.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 3
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 2% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:2:0.5.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 4
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 2% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:4:0.5.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 5
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 2% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:2:1.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 6
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 2% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:4:1.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 7
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 2.5% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:4:1.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Embodiment 8
A kind of disposable hand-wrist bones gel of environment-friendly type, by weight percentage, including following components: fungicide 0.5%, thickening
Agent 0.6%, the polyalcohol 1% that carbon atom number is 2~6, pH adjusting agent 0.1%, loquat extract 0.5%, water surplus.
The fungicide is chela polyguanidine.
The thickener is Carbopol 941.
The polyalcohol that the carbon atom number is 2~6 be propylene glycol, glycerol, butanediol mixture, it is the propylene glycol, sweet
The weight part ratio of oil and butanediol is 1:4:1.
The pH adjusting agent is triethanolamine.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 1
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that institute
Stating the polyalcohol that carbon atom number is 2~6 is propylene glycol.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 2
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that institute
Stating the polyalcohol that carbon atom number is 2~6 is glycerol.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 3
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that institute
Stating the polyalcohol that carbon atom number is 2~6 is butanediol.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 4
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that institute
Stating loquat extract is 0.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 5
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that carbon
Polyalcohol 0.01%, loquat extract 0.01% of the atomicity for 2~6.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Comparative example 6
A kind of disposable hand-wrist bones gel of environment-friendly type, concrete component and weight percent are with embodiment 8, the difference lies in that carbon
Polyalcohol 4%, loquat extract 1% of the atomicity for 2~6.
A kind of preparation method of disinfecting gel, the specific steps are the same as those in embodiment 1.
Performance test
The disinfecting gel described in embodiment and comparative example carries out performance detection, the results are shown in Table 1.
(1) Germicidal test: acting on 1min with disinfecting gel, the disinfecting gel of Examples 1 to 8 to Escherichia coli,
Staphylococcus aureus, Candida albicans, pseudomonas aeruginosa killing logarithm >=3.
(2) hand on-site disinfection test: choosing 140 25~45 years old women is object on probation, is divided into 14 groups, every group 10
People respectively tests the disinfecting gel of embodiment and comparative example, acts on 1min with disinfecting gel, tests the nature of watch face
Bacterium averagely kills logarithm.
(3) sensory evaluation: choosing 140 25~45 years old women is object on probation, is divided into 14 groups, and every group of 10 people distinguish
The water retention property that disappears is evaluated to the disinfecting gel of embodiment and comparative example.Using effect total score is 5 points, in which: 5 points indicate fine；4
It is divided into preferably；3 points are that can receive；3 points the following are bad or cannot receive.
1 disinfecting gel Evaluation results of table
The above described is only a preferred embodiment of the present invention, be not the limitation for making other forms to invention, it is any
Those skilled in the art are changed or are changed to the equivalent of equivalent variations possibly also with the technology contents of the disclosure above
Embodiment, but without departing from the technical solutions of the present invention, above embodiments are made according to the technical essence of the invention
Any simple modification, equivalent variations and remodeling, still fall within the protection scope of technical solution of the present invention.
Claims (10)
1. a kind of disposable hand-wrist bones gel of environment-friendly type, which is characterized in that including following components: fungicide, thickener, carbon atom number
For 2~6 polyalcohol, pH adjusting agent, loquat extract, water；
Wherein, the fungicide is selected from least one of chela polyguanidine, polyhexamethylene guanide, poly hexamethylene biguanide.
2. disinfecting gel as described in claim 1, which is characterized in that by weight percentage, including following components: fungicide
0.1~1%, thickener 0.1~1%, carbon atom number be 2~6 polyalcohol 0.01~4%, pH adjusting agent 0.01~0.2%,
Loquat extract 0.01~1%, water surplus.
3. disinfecting gel as described in claim 1, which is characterized in that the fungicide is chela polyguanidine.
4. disinfecting gel as described in claim 1, which is characterized in that the thickener is Carbomer thickener and/or fibre
Tie up plain class thickener.
5. disinfecting gel as claimed in claim 4, which is characterized in that the thickener is Carbomer thickener.
6. disinfecting gel as described in claim 1, which is characterized in that the polyalcohol that the carbon atom number is 2~6 is selected from second two
At least one of alcohol, propylene glycol, butanediol, glycerol, erythrite, xylitol, D-glucitol, inositol.
7. disinfecting gel as claimed in claim 6, which is characterized in that the polyalcohol that the carbon atom number is 2~6 is the third two
Alcohol, glycerol, butanediol mixture.
8. disinfecting gel as claimed in claim 7, which is characterized in that the polyalcohol and loquat that the carbon atom number is 2~6 mention
Taking the sum of weight percent of object is 0.1~4%.
9. disinfecting gel as described in claim 1, which is characterized in that by weight percentage, the gel component further includes
Auxiliary agent 0~3%.
10. a kind of preparation method of gel as described in any one of claims 1 to 8, which comprises the following steps:
(1) thickener is added to the water, stands 30~50 hours；
(2) loquat extract, the polyalcohol that carbon atom number is 2~6 are added in step (1) resulting solution；
(3) into step (2), gained mixed liquor addition fungicide is stirred；
(4) stir evenly to pH adjusting agent is added in gained mixed solution in step (3), be made gel to get.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135302A (en) * | 2020-01-17 | 2020-05-12 | 稳领(天津)医学科技有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
| CN111346020A (en) * | 2020-04-10 | 2020-06-30 | 广州云丽生物科技有限公司 | Monoguanidine washing-free disinfection gel and preparation method thereof |
| CN111840188A (en) * | 2020-09-03 | 2020-10-30 | 青岛格林维尔环保技术有限公司 | Nursing type hand-washing-free disinfection gel and preparation method thereof |
| CN111956659A (en) * | 2020-09-03 | 2020-11-20 | 青岛格林维尔环保技术有限公司 | Washing-free disinfection hand washing gel and preparation method thereof |
| CN112245334A (en) * | 2020-09-18 | 2021-01-22 | 江苏龙蟠科技股份有限公司 | Alcohol-free hand-washing-free disinfection gel and preparation method thereof |
| CN113288860A (en) * | 2021-03-11 | 2021-08-24 | 江西车仆实业有限公司 | Convenient and easy-to-produce hand-washing-free disinfection gel and preparation method thereof |
| CN113952246A (en) * | 2021-12-06 | 2022-01-21 | 安福超威日化有限公司 | A kind of cationic antibacterial hand-washing gel and preparation method thereof |
| CN113967179A (en) * | 2020-07-23 | 2022-01-25 | 山东菏泽三仪生物工程有限公司 | Washing-free hand disinfection gel with skin care effect and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111135302A (en) * | 2020-01-17 | 2020-05-12 | 稳领(天津)医学科技有限公司 | Hand-washing-free disinfection gel and preparation method thereof |
| CN111346020A (en) * | 2020-04-10 | 2020-06-30 | 广州云丽生物科技有限公司 | Monoguanidine washing-free disinfection gel and preparation method thereof |
| CN113967179A (en) * | 2020-07-23 | 2022-01-25 | 山东菏泽三仪生物工程有限公司 | Washing-free hand disinfection gel with skin care effect and preparation method thereof |
| CN111840188A (en) * | 2020-09-03 | 2020-10-30 | 青岛格林维尔环保技术有限公司 | Nursing type hand-washing-free disinfection gel and preparation method thereof |
| CN111956659A (en) * | 2020-09-03 | 2020-11-20 | 青岛格林维尔环保技术有限公司 | Washing-free disinfection hand washing gel and preparation method thereof |
| CN112245334A (en) * | 2020-09-18 | 2021-01-22 | 江苏龙蟠科技股份有限公司 | Alcohol-free hand-washing-free disinfection gel and preparation method thereof |
| CN113288860A (en) * | 2021-03-11 | 2021-08-24 | 江西车仆实业有限公司 | Convenient and easy-to-produce hand-washing-free disinfection gel and preparation method thereof |
| CN113952246A (en) * | 2021-12-06 | 2022-01-21 | 安福超威日化有限公司 | A kind of cationic antibacterial hand-washing gel and preparation method thereof |
| CN113952246B (en) * | 2021-12-06 | 2023-09-22 | 安福超威日化有限公司 | A kind of cationic antibacterial hand-washing gel and preparation method thereof |
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Application publication date: 20190521 |