CN109770981A - It is a kind of for post-surgical incisions suture wire ligature or skin nail and preparation method thereof - Google Patents
It is a kind of for post-surgical incisions suture wire ligature or skin nail and preparation method thereof Download PDFInfo
- Publication number
- CN109770981A CN109770981A CN201910117484.0A CN201910117484A CN109770981A CN 109770981 A CN109770981 A CN 109770981A CN 201910117484 A CN201910117484 A CN 201910117484A CN 109770981 A CN109770981 A CN 109770981A
- Authority
- CN
- China
- Prior art keywords
- suture
- post
- preparation
- surgical incisions
- wire ligature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Materials For Medical Uses (AREA)
Abstract
The invention discloses a kind of wire ligatures for post-surgical incisions suture or skin nail and preparation method thereof, this method is to utilize fuse autofrettage, after metal powder is melted, pass through electrostatic wire drawing, deposition modeling, obtains wire ligature or Pi Ding, and diameter is not more than 10 μm, and uniform surface, post-surgical incisions suture can be used for.The present invention passes through the means of electrostatic wire drawing after melting metal powder using fuse autofrettage (FFF), diameter can be obtained in 10 μm and the wire ligature or Pi Ding of uniform surface, this suture or skin nail have suitable mechanical property, and promoting the biological activity of regeneration possessed by metal, the suture or skin nail for complying fully with clinical use require.
Description
Technical field
The present invention relates to a kind of medical instruments, and in particular to a kind of wire ligature or Pi Ding for post-surgical incisions suture
And preparation method thereof.
Background technique
Operation is the effective means of the various diseases of medical treatment of surgery.But it performs the operation while being also that a kind of pair of human body causes
The treatment means of direct wound.By cutting skin, tissue or even bone et al. body important feature, lesion of going directly allows surgery to cure
Life can remove diseased region directly to achieve the purpose that treat disease.
And the wound as caused by surgical procedure, then it is usually to be sutured with sutures.It is clinically used at present
Sutures are broadly divided into two classes: the first kind is absorbable suture, including catgut, chemical synthesis line and collagen suture.
Second class is nonabsorable suture, i.e., the suture that can not be absorbed by tissue.The material of this kind of suture is mainly by nylon, stainless
Steel or cotton composition.These traditional operative incision suture materials have many advantages, such as that property is stablized, good biocompatibility, but are a lack of
Promote the biological activity of wound healing.
In order to seek with the biomaterial for promoting notch faster to heal, we have focused on sight and have been referred to as one's own object
Above the tantalum of metal.Tantalum itself does not have any toxic side effect for human body, has suitable mechanical strength and outstanding biology
Activity has the function of promoting bone and soft tissue regeneration.
Traditional metal 3D printing technique, such as selective laser fusion technology (Selective Laser Melting, letter
Claim SLM), the printing precision of electron beam melting technology (Electron Beam Melting, abbreviation EBM) is limited, the seam printed
Situations such as line most carefully can only achieve 100 μm or so, and will appear fracture of wire during printing, rough surface makes to print suture
Intensity is affected, and the line footpath specification 6-0# of clinical use and suture diameter below only have 70 μm.So using traditional
Metallic print technology is difficult to make satisfactory sutures.
Summary of the invention
The object of the present invention is to provide diameters not higher than 10 μm and the wire ligature of uniform surface, this suture have conjunction
Promote the biological activity of regeneration possessed by the metals such as suitable mechanical property and tantalum, niobium.Comply fully with clinical use
Suture requirement.
" Pi Ding " as described herein refers to suturing nail.
The selection of " suture ", " Pi Ding " of this paper, which uses, depends on cut closure mode.
In order to achieve the above objectives, the present invention provides the systems of a kind of wire ligature for post-surgical incisions suture or skin nail
Preparation Method, this method are using fuse autofrettage, and after metal powder is melted, by electrostatic wire drawing, deposition modeling obtains metal seam
Line or Pi Ding.
Preferably, melting temperature is 2200-3000 DEG C, print platform voltage is 10KV-50KV.
Preferably, the metal powder is by hydrogenating powder preparation processed.
Preferably, the hydrogenation flouring technology refers to: by metal material hydrogenation treatment, and successively through being crushed at ball milling
Reason, screening process, Shape correction and post-treatment after dehydrogenation, obtain metal powder.
Preferably, any one of the metal in tantalum, titanium tantalum alloy, titanium tantalum niobium zirconium alloy.
Preferably, the titanium tantalum niobium zirconium alloy is made of the metallic element of following mass percentage: titanium 60%, tantalum
2%, niobium 34%, zirconium 4%.
Tantalum and niobium itself do not have any toxic side effect for human body, have suitable mechanical strength and outstanding biology living
Property, have the function of promoting bone and soft tissue regeneration.
Preferably, the wire ligature or skin nail diameter are not more than 10 μm, and uniform surface.
The present invention also provides a kind of using wire ligature made from above-mentioned preparation method, and the diameter of the wire ligature is not
Greater than 10 μm, and uniform surface, post-surgical incisions suture can be used for.
It is followed closely the present invention also provides a kind of using metal skin made from above-mentioned preparation method, it is little which follows closely diameter
In 10 μm, and uniform surface, post-surgical incisions suture can be used for.
Compare the sutures or Pi Ding using traditional material (stainless steel, nylon, titanium alloy) preparation, metal of the invention
Suture or skin nail have the advantage that 1) there is good biocompatibility, will appear foreign body reaction without worrying；2) suture or skin
It biologically active ingredient is followed closely, can play the role of promoting skin, muscle and fibr tissue reparation, be conducive to notch earlier
Healing substantially increases the efficiency of operative incision healing；3) quick acting fuse manufacture (Fast Fuse Fabrication, letter are utilized
Claim FFF) preparation wire ligature or skin nail diameter be not more than 10 μm, and have uniform surface texture, in process of clinical application
In have higher safety.
Specific embodiment
The following further describes the technical solution of the present invention with reference to embodiments.
Embodiment 1
1, ta powder is prepared
The tantalum powder for meeting 3D printing requirement is prepared, using the method for hydrogenating powder processed to ensure to prepare by 3D printing technique
Meet the suture of clinical operation suture requirement out.
By metal material hydrogenation treatment, and successively through broken ball-milling treatment, screening process (guarantee mobility), shaping at
Reason and post-treatment after dehydrogenation, obtain metal powder.The purpose of the screening process is to guarantee that mobility is 20-50g/12Sec.It is described
Shape correction purpose be control particle size range between 200mu~400mu.
2, tantalum wire ligature is prepared
The tantalum metal powder of preparation is subjected to high-temperature fusion, 2700-3000 DEG C, then, molten metal liquid passes through FFF
(wire diameter come out from printer nozzle is 100-200 μm or so to the high-pressure electrostatic power of technology print platform, passes through platform
High-pressure electrostatic power by nozzle wire puncture to 10-20 μm or so), by tantalum material by way of electric field wire drawing, make
Its deposition modeling obtains diameter less than 10 μm and the tantalum wire ligature of uniform surface.Print parameters are as follows: 2700-3000 DEG C, put down
Platform voltage is 10KV-50KV.The FFF technology print platform is that Fraunhofer ceramic technology and system research institute (IKTS) are autonomous
The printer of repacking.
Embodiment 2
Ta powder is prepared using the identical method of embodiment 1.
The tantalum metal powder of preparation is subjected to high-temperature fusion, then, the height that molten metal liquid is passed through print platform
Press electrostatic force by tantalum material by way of wire drawing by its deposition modeling, obtain diameter less than 10 μm and the tantalum of uniform surface gold
Belong to skin nail.The preparation method is the same as that of Example 1 by FFF, only different with the path designed in computer.The path of suture is straight line, skin
The path of nail is H-type.
Embodiment 3
1, titanium tantalum niobium zirconium alloy powder is prepared
The titanium tantalum niobium zirconium alloy powder for meeting 3D printing requirement is prepared, using the method for hydrogenating powder processed in the hope of passing through 3D printing
Technology prepares the suture for meeting clinical operation suture requirement.
Firstly, by titanium tantalum niobium zirconium alloy material (titanium 60%, tantalum 2%, niobium 34%, zirconium 4%, following mass percentage) hydrogen
Change processing, and successively titanium tantalum niobium zirconium alloy powder is obtained through broken ball-milling treatment, screening process, Shape correction and post-treatment after dehydrogenation.
2, titanium tantalum niobium zirconium alloy suture is prepared
The titanium tantalum niobium zirconium alloy powder of preparation is subjected to high-temperature fusion, 2200-2600 DEG C of melt temperature, then, will be melted
Metal liquid the high-pressure electrostatic power of print platform by titanium tantalum niobium zirconium alloy material by wire drawing by way of be deposited into
Type obtains diameter less than 10 μm and the titanium tantalum niobium zirconium alloy suture of uniform surface.Print parameters are as follows: 2200-2600 DEG C, platform
Voltage is 10KV-50KV.The FFF technology print platform is that Fraunhofer ceramic technology independently changes with system research institute (IKTS)
The printer of dress.
Embodiment 4
Titanium tantalum niobium zirconium alloy powder is prepared using the identical method of embodiment 3.
The titanium tantalum niobium zirconium alloy powder of preparation is subjected to high-temperature fusion, 2200-2600 DEG C of melt temperature then, by melting
Metal liquid the high-pressure electrostatic power of print platform by titanium tantalum niobium zirconium alloy material by wire drawing by way of by its deposition modeling,
Diameter is obtained less than 10 μm and the titanium tantalum niobium zirconium alloy skin of uniform surface is followed closely.Print parameters are as follows: 2200-2600 DEG C, platform electricity
Pressure is 10KV-50KV.The FFF technology print platform is that Fraunhofer ceramic technology and system research institute (IKTS) are independently reequiped
Printer.
In conclusion the present invention is melted the metals such as tantalum, titanium tantalum alloy or titanium tantalum niobium zirconium alloy using fuse autofrettage (FFF)
The means for passing through electrostatic wire drawing after melting obtain diameter in 10 μm and the wire ligature of uniform surface, and this suture has suitable
Mechanical property and tantalum, niobium etc. possessed by promote the biological activity of regeneration, comply fully with the suture of clinical use
It is required that.
It is discussed in detail although the contents of the present invention have passed through above preferred embodiment, but it should be appreciated that above-mentioned
Description is not considered as limitation of the present invention.After those skilled in the art have read above content, for of the invention
A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.
Claims (9)
1. a kind of preparation method that wire ligature or skin for post-surgical incisions suture are followed closely, which is characterized in that this method is benefit
With fuse autofrettage, after metal powder is melted, by electrostatic wire drawing, deposition modeling obtains wire ligature or Pi Ding.
2. the preparation method for the wire ligature of post-surgical incisions suture as described in claim 1, which is characterized in that melting
Temperature is 2200-3000 DEG C, and print platform voltage is 10KV-50KV.
3. the preparation method for the wire ligature of post-surgical incisions suture as described in claim 1, which is characterized in that described
Metal powder by hydrogenating powder processed preparation.
4. the preparation method for the wire ligature of post-surgical incisions suture as claimed in claim 3, which is characterized in that described
Hydrogenation flouring technology refer to: by metal material hydrogenation treatment, and successively through broken ball-milling treatment, screening process, Shape correction
And post-treatment after dehydrogenation, obtain metal powder.
5. the preparation method for the wire ligature of post-surgical incisions suture as claimed in claim 4, which is characterized in that described
Any one in tantalum, titanium tantalum alloy, titanium tantalum niobium zirconium alloy of metal material.
6. the preparation method for the wire ligature of post-surgical incisions suture as claimed in claim 5, which is characterized in that described
Titanium tantalum niobium zirconium alloy be made of the metallic element of following mass percentage: titanium 60%, tantalum 2%, niobium 34%, zirconium 4%.
7. the preparation method for the wire ligature of post-surgical incisions suture as described in claim 1, which is characterized in that described
Wire ligature or skin nail diameter be not more than 10 μm, and uniform surface.
8. a kind of using wire ligature made from preparation method described in any one of claim 1-7, which is characterized in that should
The diameter of wire ligature is not more than 10 μm, and uniform surface, can be used for post-surgical incisions suture.
9. a kind of followed closely using metal skin made from preparation method described in any one of claim 1-7, which is characterized in that should
Metal skin follows closely diameter and is not more than 10 μm, and uniform surface, can be used for post-surgical incisions suture.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910117484.0A CN109770981B (en) | 2019-02-15 | 2019-02-15 | Metal suture or skin nail for postoperative incision suturing and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910117484.0A CN109770981B (en) | 2019-02-15 | 2019-02-15 | Metal suture or skin nail for postoperative incision suturing and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109770981A true CN109770981A (en) | 2019-05-21 |
| CN109770981B CN109770981B (en) | 2022-04-01 |
Family
ID=66504331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910117484.0A Active CN109770981B (en) | 2019-02-15 | 2019-02-15 | Metal suture or skin nail for postoperative incision suturing and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109770981B (en) |
Citations (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87205213U (en) * | 1987-10-20 | 1988-05-04 | 杨岸 | Device for performing nail therapeutical treatment |
| US5333625A (en) * | 1988-08-18 | 1994-08-02 | Rikki Brezak | Suturing with corrosion and breakage resistant flexible wire |
| CN2461493Y (en) * | 2000-12-18 | 2001-11-28 | 杨西荣 | Medical metal suture made of Ti-Ni alloy |
| CN2569749Y (en) * | 2002-10-09 | 2003-09-03 | 黄平 | Guiding medical metal wire suture |
| CN2574612Y (en) * | 2002-10-09 | 2003-09-24 | 黄平 | Hemostatic sand bag structure used in post insertion therapeutic operation of heart |
| CN1832858A (en) * | 2003-08-08 | 2006-09-13 | 夏普株式会社 | Electrostatic attraction type fluid discharge device |
| CN201676074U (en) * | 2010-02-04 | 2010-12-22 | 四川省医学科学院（四川省人民医院） | Corneal endothelial nail |
| CN203609464U (en) * | 2013-12-19 | 2014-05-28 | 宋志强 | Medical biological absorbable anastomosis assembly |
| CN203663138U (en) * | 2013-09-27 | 2014-06-25 | 上海交通大学医学院附属第九人民医院 | Degradable anti-bacterial metal suture |
| CN104441655A (en) * | 2014-10-28 | 2015-03-25 | 湖南大学 | Three-dimensional printing system for electrostatic drawing wires |
| CN104511048A (en) * | 2013-09-27 | 2015-04-15 | 上海交通大学医学院附属第九人民医院 | Degradable metal antibacterial suture |
| CN105538718A (en) * | 2016-01-15 | 2016-05-04 | 吉林大学 | 3D printing method adopting fused deposition molding |
| CN105834437A (en) * | 2016-05-16 | 2016-08-10 | 唐建中 | Preparing method of 3D printing metal powder |
| CN106388890A (en) * | 2016-10-10 | 2017-02-15 | 上海百玫医疗科技有限公司 | Monofilament operating suture line and preparation method thereof |
| CN106574412A (en) * | 2014-08-18 | 2017-04-19 | 美国俄克拉荷马州立中央大学 | Method and apparatus for controlled alignment and deposition of branched electrospun fiber |
| CN108472720A (en) * | 2015-08-24 | 2018-08-31 | 德仕托金属有限公司 | The Three-dimensional Current body dynamics of metal object print |
| US20180258512A1 (en) * | 2015-09-17 | 2018-09-13 | Nanyang Technological University | Titanium-tantalum alloy and method of forming thereof |
| CN108543107A (en) * | 2018-04-19 | 2018-09-18 | 宁波诺丁汉新材料研究院有限公司 | A kind of human body medical absorbable suture and preparation method thereof |
| CN108721707A (en) * | 2017-04-25 | 2018-11-02 | 北京纳米能源与系统研究所 | Degradable wire and its preparation method |
| CN108883575A (en) * | 2016-02-18 | 2018-11-23 | 维洛3D公司 | Accurate 3 D-printing |
-
2019
- 2019-02-15 CN CN201910117484.0A patent/CN109770981B/en active Active
Patent Citations (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87205213U (en) * | 1987-10-20 | 1988-05-04 | 杨岸 | Device for performing nail therapeutical treatment |
| US5333625A (en) * | 1988-08-18 | 1994-08-02 | Rikki Brezak | Suturing with corrosion and breakage resistant flexible wire |
| CN2461493Y (en) * | 2000-12-18 | 2001-11-28 | 杨西荣 | Medical metal suture made of Ti-Ni alloy |
| CN2569749Y (en) * | 2002-10-09 | 2003-09-03 | 黄平 | Guiding medical metal wire suture |
| CN2574612Y (en) * | 2002-10-09 | 2003-09-24 | 黄平 | Hemostatic sand bag structure used in post insertion therapeutic operation of heart |
| CN1832858A (en) * | 2003-08-08 | 2006-09-13 | 夏普株式会社 | Electrostatic attraction type fluid discharge device |
| CN201676074U (en) * | 2010-02-04 | 2010-12-22 | 四川省医学科学院（四川省人民医院） | Corneal endothelial nail |
| CN104511048A (en) * | 2013-09-27 | 2015-04-15 | 上海交通大学医学院附属第九人民医院 | Degradable metal antibacterial suture |
| CN203663138U (en) * | 2013-09-27 | 2014-06-25 | 上海交通大学医学院附属第九人民医院 | Degradable anti-bacterial metal suture |
| CN203609464U (en) * | 2013-12-19 | 2014-05-28 | 宋志强 | Medical biological absorbable anastomosis assembly |
| CN106574412A (en) * | 2014-08-18 | 2017-04-19 | 美国俄克拉荷马州立中央大学 | Method and apparatus for controlled alignment and deposition of branched electrospun fiber |
| CN104441655A (en) * | 2014-10-28 | 2015-03-25 | 湖南大学 | Three-dimensional printing system for electrostatic drawing wires |
| CN108472720A (en) * | 2015-08-24 | 2018-08-31 | 德仕托金属有限公司 | The Three-dimensional Current body dynamics of metal object print |
| US20180258512A1 (en) * | 2015-09-17 | 2018-09-13 | Nanyang Technological University | Titanium-tantalum alloy and method of forming thereof |
| CN105538718A (en) * | 2016-01-15 | 2016-05-04 | 吉林大学 | 3D printing method adopting fused deposition molding |
| CN108883575A (en) * | 2016-02-18 | 2018-11-23 | 维洛3D公司 | Accurate 3 D-printing |
| CN105834437A (en) * | 2016-05-16 | 2016-08-10 | 唐建中 | Preparing method of 3D printing metal powder |
| CN106388890A (en) * | 2016-10-10 | 2017-02-15 | 上海百玫医疗科技有限公司 | Monofilament operating suture line and preparation method thereof |
| CN108721707A (en) * | 2017-04-25 | 2018-11-02 | 北京纳米能源与系统研究所 | Degradable wire and its preparation method |
| CN108543107A (en) * | 2018-04-19 | 2018-09-18 | 宁波诺丁汉新材料研究院有限公司 | A kind of human body medical absorbable suture and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 马昊鹏等: "高压静电辅助聚合物熔融沉积快速成型工艺 ", 《工程塑料应用》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109770981B (en) | 2022-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Davis et al. | A comprehensive review on metallic implant biomaterials and their subtractive manufacturing | |
| Sarraf et al. | A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applications | |
| US12137952B2 (en) | Methods, devices, and manufacture of the devices for musculoskeletal reconstructive surgery | |
| US12097089B2 (en) | Trabecular porous tantalum dental implant and preparation method thereof | |
| Chen et al. | Metallic implant biomaterials | |
| Datta et al. | Advanced materials in biological implants and surgical tools | |
| CN104546103A (en) | Absorbable intraosseous fixing device with biological activity and plasticity and forming method | |
| Zhai et al. | Research progress of metal-based additive manufacturing in medical implants | |
| Ahmed et al. | Precision machining of medical devices | |
| CN109770981A (en) | It is a kind of for post-surgical incisions suture wire ligature or skin nail and preparation method thereof | |
| CN112916869A (en) | Forming method of antibacterial titanium alloy surgical implant | |
| CN103720527A (en) | Joint fusion cage | |
| Al-Tamimi et al. | A review on powder bed fusion additive manufacturing for metallic fixation implants | |
| Krivtsun et al. | Welding in medicine applications | |
| CN109771101A (en) | Bionical bone trabecula of a kind of metal for cancellous bone defect reparation and preparation method thereof | |
| Saini et al. | Selective laser melting of CoCr alloys in biomedical application: a review | |
| JP7169014B2 (en) | Low modulus corrosion resistant alloy | |
| Ghiban et al. | Fractographic evaluation of the metallic materials for medical applications | |
| Yılmaz et al. | Investigation of Titanium-Based Biomaterials Used in Implant Applications | |
| Al-Tamimi et al. | Manufacturing for Metallic Fixation Implants | |
| CN208942490U (en) | Ankle joint fusion cage | |
| Van der Merwe | Manufacturing of custom-made medical implants for cranio/maxillofacial and orthopaedic surgery-an overview of the current state of the industry | |
| Vasudev et al. | Application of thermal claddings for materials used as biomedical implants | |
| Yadav et al. | 10 Scope of | |
| Maji et al. | Additive Manufacturing of Orthopaedic Implants |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |