CN109700576A - Technology for repairing skull by using stem cells and natural fibers - Google Patents
Technology for repairing skull by using stem cells and natural fibers Download PDFInfo
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- CN109700576A CN109700576A CN201910047423.1A CN201910047423A CN109700576A CN 109700576 A CN109700576 A CN 109700576A CN 201910047423 A CN201910047423 A CN 201910047423A CN 109700576 A CN109700576 A CN 109700576A
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Abstract
本发明公开了一种利用干细胞、天然纤维进行颅骨修补的技术，涉及干细胞生物技术领域，包括主体和颅骨粉碎机，所述主体的内壁设置有显示器，且显示器的上方安置有控制器，所述控制器与主体的内壁相连接，且控制器的上方外接有电池。本发明的有益效果是：该利用干细胞、天然纤维进行颅骨修补的技术，通过对混合器、成型基板、颅骨粉碎机和第一管体的设置，且混合器的底端与成型基板的顶端相贴合，通过成型基板对颅骨再造的原料进行承载操作，并且在其它组件的配合作用下，实现颅骨再造成型的工作，且在骨瓣减压手术的同时实现了个性化、定制化颅骨再造，再造颅骨吻合好，效率高，半小时左右即可制作完成，不影响、不耽误手术进行。
The invention discloses a technology for repairing skull by using stem cells and natural fibers, and relates to the field of stem cell biotechnology, including a main body and a skull crusher. A display is arranged on the inner wall of the main body, and a controller is arranged above the display. The controller is connected with the inner wall of the main body, and a battery is externally connected above the controller. The beneficial effects of the present invention are: the technology of using stem cells and natural fibers to repair skulls, through the arrangement of the mixer, the forming base plate, the skull crusher and the first pipe body, and the bottom end of the mixer and the top end of the forming base plate are in contact with each other. Fitting, the raw materials for skull reconstruction are carried through the forming base plate, and under the cooperation of other components, the work of skull reconstruction is realized, and personalized and customized skull reconstruction is realized at the same time as the bone flap decompression operation. The reconstructed skull has good anastomosis and high efficiency, and can be completed in about half an hour, without affecting or delaying the operation.
Description
Technical field
It is specially a kind of to be repaired using stem cell, natural fiber progress skull the present invention relates to stem cell biological technical field
The technology of benefit.
Background technique
With the development of science and technology and the progress of social times, medical technology is more and more flourishing, and craniocerebral trauma, brain go out
When intracranial hypertension occurs in blood, consistent both at home and abroad at present all to use decompressive craniectomy, purpose is exactly to make the brain tissue of swelling free
Between expand and release stress, the skull of removal can also release certain space, to reach decompression purpose, but artificial make
At " skull defeci ", after removing bone flap decompression operation, usually need to carry out cranioplasty surgery again after 3-6 months.
Existing skull defect repair material generallys use titanium net (to do two-dimensional design, three-dimensional process, computer moulding etc.),
Titanium poor biocompatibility, disadvantage are more.Now best materials for use in skull-fixing is PEEK material, but expensive.Above two
The moulding process of kind material all uses traditional manufacturing technology, and production process is complicated, the period is long, at high cost, and is performing the operation
When also plasticity is carried out according to the skull prototype of different patients, be difficult to moulding not to the utmost as primordial skull bone and occupy a large amount of valuable
Operating time.
Summary of the invention
The purpose of the present invention is to provide a kind of technologies that skull repairing is carried out using stem cell, natural fiber, solve
The problems mentioned above in the background art.
To achieve the above object, the invention provides the following technical scheme: a kind of carry out skull using stem cell, natural fiber
The technology of repairing, including main body and skull pulverizer, the inner wall of the main body are provided with display, and the top placement of display
There is controller, the controller is connected with the inner wall of main body, and battery is circumscribed with above controller, the skull pulverizer
It is installed on the inner wall top of main body, and is provided with the first tube body immediately below skull pulverizer, outside the outside of first tube body
It is connected to the second tube body, the inner wall side of the main body is provided with silk disk, and the positioned beneath of silk disk has silk to be plated in machine, institute
It states the silk that silk disk is wound by outer wall and is plated in machine with silk and be connected, and silk is plated in machine and the inner wall of main body is mutually fixed,
The main body is internally provided with shaping substrate, and the top middle portion of shaping substrate is mounted with mixer, the shaping substrate
Top side is provided with third tube body, and increasing material manufacturing shaping mechanism, and increasing material manufacturing molding machine are mounted on the inside of the main body
The inside of structure is equipped with H mechanism driving system, includes gantry on the inside of the H mechanism driving system, and outside the middle part of gantry
Side is provided with print head, and the top of the print head is mounted with feed system, is provided with transfer assembly at the top of the gantry.
Optionally, the central axes of the skull pulverizer and the central axes of the first tube body coincide, and skull pulverizer with
It is to be fixedly connected between main body.
Optionally, the shape of second tube body matches with the shape of third tube body, and the center line of the second tube body with
The center line of first tube body is parallel.
Optionally, to be flexibly connected between the silk disk and main body, and the middle part outer wall structure cylindrical of silk disk.
Optionally, the bottom end of the mixer and the top of shaping substrate fit, and the top end opening width of mixer
Greater than the distance between the first tube body and the second tube body.
Optionally, include wire feeding device on the inside of the feed system, be circumscribed with dispensing on the outside of the wire feeding device
Mechanism, and the positioned beneath of wire feeding device, glue applying mechanism has cooling mechanism, the bottom of the cooling mechanism is connected with heater
Structure, and the positioned beneath of heating mechanism has spray head.
Optionally, the line of symmetry of the glue applying mechanism and the line of symmetry of wire feeding device coincide, and the outside of wire feeding device
Be serrated structure.
Optionally, the inside of the cooling mechanism and the inside of heating mechanism are in connected state structure, and heating mechanism is in circle
Column structure setting.
Optionally, channel width on the inside of the spray head is less than the channel width on the inside of heating mechanism, and heating mechanism
Top and the bottom end of cooling mechanism fit closely.
The present invention provides a kind of technologies that skull repairing is carried out using stem cell, natural fiber, have following beneficial to effect
Fruit:
1, technology that skull repairing is carried out using stem cell, natural fiber, by being crushed to mixer, shaping substrate, skull
The setting of machine and the first tube body, and the bottom end of mixer and the top of shaping substrate fit, by shaping substrate to skull again
The raw material made carries out carrying operation, and under the mating reaction of other components, realizes that skull reproduces molding work, and in bone
Personalized, customization skull reconstruction is realized while valve decompression operation, reconstruction skull coincide, high-efficient, or so half an hour
It can complete, not influence, do not delay operation progress, and the central axes of skull pulverizer are mutually be overlapped with the central axes of the first tube body
It closes, under the effect of the Relative distribution of skull pulverizer and the first tube body, so that the smashed material of skull pulverizer is in a vertical shape
It slides to the first tube body, raw material is avoided to spill, influence subsequent skull reconstruction shaping work.
2, technology that skull repairing is carried out using stem cell, natural fiber, by the second tube body, third tube body, silkworm
The setting of wire tray and main body, and the shape of the second tube body matches with the shape of third tube body, passes through the second tube body and third pipe
The effect of body can carry out hybrid manipulation to addition biogum in mixer respectively and discharge stem cell to shaping substrate,
It is convenient for skull reconstruction work, and to be flexibly connected between silk disk and main body, the activity between silk disk and main body is even
Connect under effect, convenient for silk be plated in machine to silk need using when, realize the purpose quickly taken.
3, technology that skull repairing is carried out using stem cell, natural fiber, by glue applying mechanism and wire feeding device
Setting, and the line of symmetry of glue applying mechanism and the line of symmetry of wire feeding device coincide, and pass through the opposite of glue applying mechanism and wire feeding device
Distribution effect, so that glue applying mechanism carries out silk to need the mating reaction by wire feeding device when dispensing, it is more preferable convenient for silk
Conveying and the work such as gluing progress.
4, technology that skull repairing is carried out using stem cell, natural fiber, by cooling mechanism and heating mechanism
Setting, and the inside of cooling mechanism and the inside of heating mechanism are in connected state structure, cooling mechanism and heating mechanism both
Inside in connection under the action of so that both inner channel to the consistent by effect of silk, is not easy because of channel width not
One the phenomenon that, influences transportation work when silk is heated, radiated.
5, the technology that skull repairing is carried out using stem cell, natural fiber, by the setting to spray head and heating mechanism,
And the channel width on the inside of spray head be less than heating mechanism on the inside of channel width, by the channel on the inside of spray head to silk carry out into
One step limit operation, so that the silk after heating carries out injection operation by spray head, until carrying out skull reconstruction on shaping substrate
Work.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram for the technology that skull repairing is carried out using stem cell, natural fiber of the present invention；
Fig. 2 is that a kind of H mechanism driving system structure for the technology for carrying out skull repairing using stem cell, natural fiber of the present invention is shown
It is intended to；
Fig. 3 is a kind of feed system structural schematic diagram for the technology that skull repairing is carried out using stem cell, natural fiber of the present invention；
Fig. 4 is that a kind of control circuit flowage structure for the technology for carrying out skull repairing using stem cell, natural fiber of the present invention is shown
It is intended to.
In figure: 1, main body；2, display；3, controller；4, battery；5, the first tube body；6, skull pulverizer；7, the second pipe
Body；8, silk disk；9, silk is plated in machine；10, mixer；11, increasing material manufacturing shaping mechanism；12, shaping substrate；13, third pipe
Body；14, gantry；15, print head；16, transfer assembly；17, feed system；18, wire feeding device；19, glue applying mechanism；20, it radiates
Mechanism；21, heating mechanism；22, spray head；23, H mechanism driving system.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
In the description of the present invention, unless otherwise indicated, the meaning of " plurality " is two or more；Term " on ",
The orientation or positional relationship of the instructions such as "lower", "left", "right", "inner", "outside", " front end ", " rear end ", " head ", " tail portion " is
It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark
Show that signified device or element must have a particular orientation, be constructed and operated in a specific orientation, therefore should not be understood as pair
Limitation of the invention.In addition, term " first ", " second ", " third " etc. are used for description purposes only, and should not be understood as instruction or
Imply relative importance.
In the description of the present invention, it should be noted that unless otherwise clearly defined and limited, term " connected " " connects
Connect " it shall be understood in a broad sense, for example, it may be being fixedly connected, it may be a detachable connection, or be integrally connected；It can be machine
Tool connection, is also possible to be electrically connected；It can be directly connected, it can also be indirectly connected through an intermediary.For this field
For those of ordinary skill, the concrete meaning of above-mentioned term in the present invention can be understood with concrete condition.
Fig. 1-4 is please referred to, the present invention provides a kind of technical solution: a kind of to repair using stem cell, natural fiber progress skull
The technology of benefit, including main body 1, display 2, controller 3, battery 4, the first tube body 5, skull pulverizer 6, the second tube body 7, silk
Disk 8, silk are plated in machine 9, mixer 10, increasing material manufacturing shaping mechanism 11, shaping substrate 12, third tube body 13, gantry 14, printing
First 15, transfer assembly 16, feed system 17, wire feeding device 18, glue applying mechanism 19, cooling mechanism 20, heating mechanism 21, spray head 22
With H mechanism driving system 23, the inner wall of main body 1 is provided with display 2, and the top of display 2 is mounted with controller 3, control
Device 3 is connected with the inner wall of main body 1, and the top of controller 3 is circumscribed with battery 4, and skull pulverizer 6 is installed on the interior of main body 1
Wall top, and the underface of skull pulverizer 6 is provided with the first tube body 5, the central axes of skull pulverizer 6 and the first tube body 5
Central axes coincide, and to be fixedly connected between skull pulverizer 6 and main body 1, in the phase of skull pulverizer 6 and the first tube body 5
To under distribution effect, slides so that the smashed material of skull pulverizer 6 is in a vertical shape to the first tube body 5, raw material is avoided to spill
Out, subsequent skull reconstruction shaping work is influenced；
The outside of first tube body 5 is circumscribed with the second tube body 7, and the shape of the second tube body 7 matches with the shape of third tube body 13, and
The center line of second tube body 7 is parallel with the center line of the first tube body 5, passes through the effect of the second tube body 7 and third tube body 13, energy
It is enough that hybrid manipulation is carried out to addition biogum in mixer 10 respectively and discharges stem cell to shaping substrate 12, it is convenient for
Skull reproduces work, and the inner wall side of main body 1 is provided with silk disk 8, and the positioned beneath of silk disk 8 has silk to be plated in machine 9, silkworm
To be flexibly connected between wire tray 8 and main body 1, and the middle part outer wall structure cylindrical of silk disk 8, silk disk 8 and main body 1 it
Between flexible connection effect under, convenient for silk be plated in machine 9 to silk need using when, realize the purpose quickly taken；
The silk that silk disk 8 is wound by outer wall is plated in machine 9 with silk and is connected, and silk is plated in inner wall phase of the machine 9 with main body 1
Fixed, main body 1 is internally provided with shaping substrate 12, and the top middle portion of shaping substrate 12 is mounted with mixer 10, mixer
10 bottom end and the top of shaping substrate 12 fit, and the top end opening width of mixer 10 is greater than the first tube body 5 and second
The distance between tube body 7 carries out carrying operation, and matching in other components by the raw material that shaping substrate 12 reproduces skull
Under cooperation is used, realize that skull reproduces molding work, the top side of shaping substrate 12 is provided with third tube body 13, main body 1
Inside is mounted with increasing material manufacturing shaping mechanism 11, and the inside of increasing material manufacturing shaping mechanism 11 is equipped with H mechanism driving system 23,
The inside of H mechanism driving system 23 includes gantry 14, and is provided with print head 15 on the outside of the middle part of gantry 14, print head 15
Top is mounted with feed system 17, and the inside of feed system 17 includes wire feeding device 18, and the outside of wire feeding device 18 is circumscribed with
Glue applying mechanism 19, and the positioned beneath of wire feeding device 18, glue applying mechanism 19 has a cooling mechanism 20, the line of symmetry of glue applying mechanism 19 with
The line of symmetry of wire feeding device 18 coincides, and the outside of wire feeding device 18 is serrated structure, by glue applying mechanism 19 with into silk
The Relative distribution of mechanism 18 acts on, so that glue applying mechanism 19 needed when dispensing through wire feeding device 18 with cooperation to silk
With preferably conveying and glue etc. the progress of work convenient for silk, the inside of cooling mechanism 20 and the inside of heating mechanism 21 are in
Connected state structure, and the cylindrical structure setting of heating mechanism 21, in both inside of cooling mechanism 20 and heating mechanism 21
Under the action of connection, so that both inner channel to the consistent by effect of silk, is not easy to show because channel width is different
As influencing transportation work when silk is heated, radiated；
The bottom of cooling mechanism 20 is connected with heating mechanism 21, and the positioned beneath of heating mechanism 21 has a spray head 22, in spray head 22
The channel width of side is less than the channel width of 21 inside of heating mechanism, and the bottom end at the top of heating mechanism 21 and cooling mechanism 20
It fits closely, further limit operation is carried out to silk by the channel of 22 inside of spray head, so that the silk after heating is by spray
First 22 carry out injection operation, until carrying out skull on shaping substrate 12 and reproducing work, the top of gantry 14 is provided with transfer assembly
16。
In conclusion this carries out the technology of skull repairing using stem cell, natural fiber, in use, passing through work first
Personnel cause the patient of intracranial hypertension to carry out bone flap decompression operation, at the same time, energy craniocerebral trauma or cranial vascular disease
It is enough to crush the patient's cranial bone flap removed in operation by the skull pulverizer 6 in the device, and in skull pulverizer 6
Under the Relative distribution effect of the first tube body 5, slide so that the smashed material of skull pulverizer 6 is in a vertical shape to the first tube body
In 5, raw material is avoided to spill, then by discharging in the first tube body 5 into mixer 10, then, the biogum with the release of the second tube body 7
It is mixed in mixer 10, and spreads auxiliary on the shaping substrate 12 being made of silk, and silk needs to be plated in by silk
Machine 9 such as is handled it, is arranged at the work, the grid of homalographic is formed convenient for it, and skeletal grain is then embedded into the small of silk net
It in lattice, after being plated in, carries out striking off operation by sandwich, and then stem cell transplantation machine also presses grid according to process control
The stem cell of 13 inside of third tube body is plated in wherein by line, and after the completion of being plated in, increasing material manufacturing shaping mechanism 11 prints previously again
In same silk grid covering, at this point, the identical bone flap of same patient's skull has been made into, finally, will again by staff
The skull made is implanted into back in patient's cranium brain.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (9)
1. a kind of technology that skull repairing is carried out using stem cell, natural fiber, including main body (1) and skull pulverizer (6),
Be characterized in that: the inner wall of the main body (1) is provided with display (2), and controller (3), institute are mounted with above display (2)
It states controller (3) to be connected with the inner wall of main body (1), and is circumscribed with battery (4) above controller (3), the skull crushes
Machine (6) is installed on the inner wall top of main body (1), and the first tube body (5) are provided with immediately below skull pulverizer (6), and described
It is circumscribed on the outside of one tube body (5) the second tube body (7), the inner wall side of the main body (1) is provided with silk disk (8), and silk
The positioned beneath of disk (8) has silk to be plated in machine (9), and the silk that the silk disk (8) is wound by outer wall and silk are plated in machine (9)
It is connected, and silk is plated in machine (9) and the inner wall of main body (1) is mutually fixed, the main body (1) is internally provided with shaping substrate
(12), and the top middle portion of shaping substrate (12) is mounted with mixer (10), the top side setting of the shaping substrate (12)
Have third tube body (13), is mounted with increasing material manufacturing shaping mechanism (11) on the inside of the main body (1), and increasing material manufacturing shaping mechanism
(11) inside is equipped with H mechanism driving system (23), includes gantry (14) on the inside of the H mechanism driving system (23),
And be provided with print head (15) on the outside of the middle part of gantry (14), the top of the print head (15) is mounted with feed system (17),
Transfer assembly (16) are provided at the top of the gantry (14).
2. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 1, feature are existed
In: the central axes of the skull pulverizer (6) and the central axes of the first tube body (5) coincide, and skull pulverizer (6) and main body
It (1) is to be fixedly connected between.
3. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 1, feature are existed
In: the shape of second tube body (7) matches with the shape of third tube body (13), and the center line of the second tube body (7) and
The center line of one tube body (5) is parallel.
4. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 1, feature are existed
In: to be flexibly connected between the silk disk (8) and main body (1), and the middle part outer wall structure cylindrical of silk disk (8).
5. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 1, feature are existed
In: the bottom end of the mixer (10) and the top of shaping substrate (12) fit, and the top end opening width of mixer (10)
Greater than the distance between the first tube body (5) and the second tube body (7).
6. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 1, feature are existed
In: include wire feeding device (18) on the inside of the feed system (17), is circumscribed with dispensing on the outside of the wire feeding device (18)
Mechanism (19), and the positioned beneath of wire feeding device (18), glue applying mechanism (19) has cooling mechanism (20), the cooling mechanism (20)
Bottom be connected with heating mechanism (21), and the positioned beneath of heating mechanism (21) has spray head (22).
7. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 6, feature are existed
In: the line of symmetry of the line of symmetry and wire feeding device (18) of the glue applying mechanism (19) coincides, and the outside of wire feeding device (18)
Be serrated structure.
8. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 6, feature are existed
In: the inside of the cooling mechanism (20) and the inside of heating mechanism (21) are in connected state structure, and heating mechanism (21) is in circle
Column structure setting.
9. a kind of technology for being carried out skull repairing using stem cell, natural fiber according to claim 6, feature are existed
It is less than the channel width on the inside of heating mechanism (21) in: channel width on the inside of the spray head (22), and heating mechanism (21)
The bottom end at top and cooling mechanism (20) fits closely.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201910047423.1A CN109700576A (en) | 2019-01-18 | 2019-01-18 | Technology for repairing skull by using stem cells and natural fibers |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910047423.1A CN109700576A (en) | 2019-01-18 | 2019-01-18 | Technology for repairing skull by using stem cells and natural fibers |
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