CN109568695A - A kind of hemodialyzer line clear method - Google Patents
A kind of hemodialyzer line clear method Download PDFInfo
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- CN109568695A CN109568695A CN201811256146.7A CN201811256146A CN109568695A CN 109568695 A CN109568695 A CN 109568695A CN 201811256146 A CN201811256146 A CN 201811256146A CN 109568695 A CN109568695 A CN 109568695A
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- 238000000034 method Methods 0.000 title claims abstract description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 91
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims abstract description 88
- 238000000502 dialysis Methods 0.000 claims abstract description 59
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 claims abstract description 30
- 229940033663 thimerosal Drugs 0.000 claims abstract description 30
- 239000002504 physiological saline solution Substances 0.000 claims abstract description 23
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 18
- 239000004615 ingredient Substances 0.000 claims abstract description 15
- 238000004140 cleaning Methods 0.000 claims abstract description 14
- 238000007654 immersion Methods 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims description 51
- 239000003595 mist Substances 0.000 claims description 41
- 239000007789 gas Substances 0.000 claims description 37
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 24
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 24
- 238000001631 haemodialysis Methods 0.000 claims description 20
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 16
- 238000001223 reverse osmosis Methods 0.000 claims description 15
- -1 polyoxyethylene Polymers 0.000 claims description 12
- 238000010079 rubber tapping Methods 0.000 claims description 12
- 239000008367 deionised water Substances 0.000 claims description 11
- 229910021641 deionized water Inorganic materials 0.000 claims description 11
- 238000002156 mixing Methods 0.000 claims description 10
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 8
- 239000004310 lactic acid Substances 0.000 claims description 8
- 235000014655 lactic acid Nutrition 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 241001116389 Aloe Species 0.000 claims description 6
- 239000001293 FEMA 3089 Substances 0.000 claims description 6
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 6
- 235000011399 aloe vera Nutrition 0.000 claims description 6
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 6
- 125000005456 glyceride group Chemical group 0.000 claims description 6
- 235000015141 kefir Nutrition 0.000 claims description 6
- 239000001630 malic acid Substances 0.000 claims description 6
- 235000011090 malic acid Nutrition 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 239000008267 milk Substances 0.000 claims description 6
- 210000004080 milk Anatomy 0.000 claims description 6
- 235000013336 milk Nutrition 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000000126 substance Substances 0.000 claims description 6
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 claims description 4
- 235000005979 Citrus limon Nutrition 0.000 claims description 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 238000000889 atomisation Methods 0.000 claims description 4
- 229960004504 chlorhexidine hydrochloride Drugs 0.000 claims description 4
- 230000000249 desinfective effect Effects 0.000 claims description 4
- 239000003599 detergent Substances 0.000 claims description 4
- 238000011010 flushing procedure Methods 0.000 claims description 4
- 230000001473 noxious effect Effects 0.000 claims description 4
- 239000010453 quartz Substances 0.000 claims description 4
- 238000011012 sanitization Methods 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 3
- 244000248349 Citrus limon Species 0.000 claims description 3
- 238000010790 dilution Methods 0.000 claims description 3
- 239000012895 dilution Substances 0.000 claims description 3
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 244000131522 Citrus pyriformis Species 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
- 238000011282 treatment Methods 0.000 abstract description 13
- 241000894006 Bacteria Species 0.000 abstract description 9
- 239000005416 organic matter Substances 0.000 abstract description 6
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 4
- 239000011575 calcium Substances 0.000 abstract description 4
- 230000008033 biological extinction Effects 0.000 abstract description 3
- 229910052791 calcium Inorganic materials 0.000 abstract description 3
- 239000003344 environmental pollutant Substances 0.000 abstract description 3
- 238000011900 installation process Methods 0.000 abstract description 3
- 150000002681 magnesium compounds Chemical class 0.000 abstract description 3
- 231100000719 pollutant Toxicity 0.000 abstract description 3
- 208000015181 infectious disease Diseases 0.000 abstract description 2
- 239000000243 solution Substances 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 239000003792 electrolyte Substances 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 238000007865 diluting Methods 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 238000002242 deionisation method Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000000322 hemodialysis Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012806 monitoring device Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000008399 tap water Substances 0.000 description 2
- 235000020679 tap water Nutrition 0.000 description 2
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 208000031729 Bacteremia Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- 208000033626 Renal failure acute Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 201000011040 acute kidney failure Diseases 0.000 description 1
- 208000012998 acute renal failure Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005868 electrolysis reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000006385 ozonation reaction Methods 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 238000007781 pre-processing Methods 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000009256 replacement therapy Methods 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/168—Sterilisation or cleaning before or after use
- A61M1/169—Sterilisation or cleaning before or after use using chemical substances
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
- A01N61/02—Mineral oils; Tar oils; Tar; Distillates, extracts or conversion products thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/42—Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/202—Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/168—Sterilisation or cleaning before or after use
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- External Artificial Organs (AREA)
Abstract
The invention proposes a kind of hemodialyzer line clear methods, atomized ozone disinfection treatment is carried out to channel interior using preceding in dialysis apparatus, bacterium can be avoided to cause damages in dialysis procedure to sufferer in bacterium and the pollutant for using preceding extinction dialysis apparatus channel interior；After atomized ozone disinfection treatment, physiological saline is accessed, air can be discharged, by being pre-processed to pipeline inner wall, dialyse convenient for subsequent；After dialysis, after being diluted with water using internal thimerosal, it is rinsed and flows immersion, the ingredient in internal thimerosal can effectively remove the calcium and magnesium compound in pipe, can dissolve each other with the organic matter in pipeline, organic matter is discharged；It rinses after impregnating, carries out atomized ozone disinfection treatment again, can effectively remove the bacterium in pipe, avoid infection；During cleaning, without dismantling pipeline, it can avoid causing secondary pollution to pipeline in installation process after the cleaning；It is easy to operate, it is worthy to be popularized.
Description
Technical field
The present invention relates to haemodialysis cleaning technology field, specially a kind of hemodialyzer line clear method.
Background technique
Haemodialysis (HD) is one of acute or chronic renal failure kidneys of patients Replacement Therapy.It is by by internal blood
Liquid is drained in vitro, through one by the dialyzer that is formed without several hollow fibres, blood electrolysis similar with concentration containing body
Matter solution (dialyzate) carries out mass exchange inside and outside hollow fibre one by one, through disperse, ultrafiltration, absorption and convective principles,
It removes intracorporal metabolic waste, maintain electrolyte and acid-base balance；Moisture excessive in vivo is removed simultaneously, and will be by purification
The whole process of blood recovery is known as haemodialysis.
The equipment of haemodialysis includes haemodialysis control unit, water process and dialyzer, collectively constitutes hemodialysis system, blood
Dialysis machine is most widely used a kind of therapeutic equipments in blood purification treatment, is that a more complicated electromechanical integration is set
It is standby, it is made of dialyzate supplying monitoring device and extracorporal circulatory system monitoring device；Water treatment system, tap water need to successively through filtering,
Except iron, softening, active carbon, reverse osmosis treatment, only reverse osmosis water can be as the thinned water of concentrate dialysate, and to tap water
A series of device for carrying out processing is water treatment system；Dialyzate is by dialysis concentrate and reverse osmosis water containing electrolyte and base
It is obtained after diluting in proportion, ultimately forms the solution close with electrolyte balance concentration, to maintain normal electrolyte level, simultaneously
Base is provided to body, to correct acid poisoning existing for patient by higher base concentration.Common dialyzate base is main
For bicarbonate, also contain a small amount of acetic acid.The unstable chemcial property of bicarbonate is easy in alkaline environment with calcium and magnesium ion
It precipitates, forms not capacitive calcium carbonate and magnesium carbonate；In dialyzer downstream flow path, there is also from patient's body fat,
Protein and organic substance；These precipitating and organic substance handle not in time will will cause pipeline narrow even blocking, serious shadow
Ring dialysis-effect；In addition dialyzer before and after use if not to pipeline carry out not in time processing can generate a large amount of germ contaminations,
The bacteremia and septicemia that can cause patient when serious jeopardize patient vitals' safety.
It before and after hemodialysis apparatus use, needs to carry out cleaning treatment and maintenance to pipeline, avoids causing dialysis pipeline
Pollution, influences using effect and patient health；But existing line clear method is relatively simple, but cleaning effect is bad, in addition
Existing cleaning method is that pipeline is disassembled to carry out cleaning-sterilizing mostly, is then installed again, not only inconvenient, and is pacified
During dress secondary pollution can be caused to pipeline.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the existing defects, provides a kind of hemodialyzer line clear side
Method can effectively solve the problems in background technique.
To achieve the above object, the invention provides the following technical scheme: a kind of hemodialyzer line clear method, including
Following steps:
S1. before haemodialysis starts, cleaning-sterilizing is carried out to pipeline；
S2. the preparation of ozone: gas source is sent into ozone generator by gas source pipe；Ozone generator is generated by quartz burner
Ultraviolet light be irradiated to the air in spiral gas storehouse, make its generate ozone；
S3. the preparation of atomized water: by ultrasonic ultrasonic delay line memory to the water containing thimerosals such as hydrogen peroxide from liquid feeding bottle into
Row atomization；
S4. the ozone prepared in atomized water obtained in step S3 and step S2 is mixed into and is disappeared containing ozone and hydrogen peroxide etc.
The water mist of noxious material；
S5. it is not necessarily to dismantle the pipeline of hemodialyzer, directly closes dialysis liquid pipeline, other pipelines is kept normally to be connected to, it will be upper
It states water mist and Medical Devices pipeline is sent by snorkel, and the tail gas containing ozone being discharged from pipeline is made to enter gas-liquid separator
It is separated, liquid enters liquid-collecting bottle by tapping valve, and gas is sent to air bag by pipeline and collects；
S6. by water mist obtained in step S4 by connecting with dialysis apparatus pipeline one end in step S5, and make to be discharged from pipeline
The tail gas containing ozone enter gas-liquid separator and separated, liquid enters liquid-collecting bottle by tapping valve, and gas passes through pipeline
It is sent to air bag collection；
S7. after sanitized, ozone generator and atomizer stop working, at this moment, in dialysis apparatus pipeline also remain water mist and
Ozone, booster pump, which works on, sucks air, and after the air of sucking is filtered, dry and clean air is by stopping
The ozone generator only to work enters atomizer, is then entered in dialysis apparatus pipeline by snorkel, and water mist and ozone are discharged；
S8. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline flows in pipeline
It is logical, the air in pipeline is discharged, dialysis liquid pipeline is then opened, after dialysis pipeline carries out a circulation, start formally into
Row haemodialysis；
S9. after the completion of haemodialysis, dialysis liquid pipeline is closed, physiological saline is continued to one circulation of circulation in pipeline, then
It is heated to 80 DEG C after adding reverse osmosis water to dilute using internal thimerosal to carry out pipeline repeated flushing 15 minutes, reuses and adds reverse osmosis water
Inside thimerosal after dilution carries out flowing and impregnates 30 minutes, and internal thimerosal is made of the ingredient mixing of following volume ratio: poly-
Ethylene oxide alkyl phenylate 0.5~5%, citric acid 10~50%, lactic acid 4~8%, malic acid 10~30%, surplus are deionized water；
S10. after impregnating, the water mist containing the disinfecting substances such as ozone and hydrogen peroxide in step S4 is accessed, is made from pipeline
The tail gas containing ozone of discharge enters gas-liquid separator and is separated, and liquid enters liquid-collecting bottle by tapping valve, and gas passes through
Pipeline is sent to air bag collection；
S11. after the inside thimerosal in pipeline being completely exhausted out, ozone generator and atomizer stop working, at this moment, dialysis apparatus
Also remain water mist and ozone in pipeline, booster pump, which works on, sucks air, dry after the air of sucking is filtered
And clean air enters atomizer by the ozone generator to stop working, then enters dialysis apparatus pipeline by snorkel
It is interior, water mist and ozone are discharged；
S12. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline is in pipeline
Air in pipeline is discharged circulation；
S13. after channel interior cleaning, be diluted with water rear detergent line outer wall using external disinfection liquid, external disinfection liquid by
The ingredient of following volume ratio mixes composition: kefir milk element 0.4~0.6%, turpentine oil 0.4~0.8%, aloe powder 0.3~0.4%, hydrochloric acid
Chlorohexidene 15~30%, glyceride citrate 0.3~0.4%, surplus are deionized water.
As a preferred technical solution of the present invention, the internal thimerosal by following volume ratio ingredient mixing group
At: polyoxyethylene alkylphenyl ether 2~4%, citric acid 20~40%, lactic acid 5~7%, malic acid 15~25%, surplus are deionization
Water.
As a preferred technical solution of the present invention, the internal thimerosal by following volume ratio ingredient mixing group
At: polyoxyethylene alkylphenyl ether 4~5%, citric acid 30~50%, lactic acid 6~8%, malic acid 20~30%, surplus are deionization
Water.
As a preferred technical solution of the present invention, the inside thimerosal and reverse osmosis that are used when being rinsed in the step S9
Water is mixed according to the ratio of 1:29, and the inside thimerosal and reverse osmosis water that when immersion uses are mixed according to the ratio of 1:24.
As a preferred technical solution of the present invention, the external disinfection liquid by following volume ratio ingredient mixing group
At: kefir milk element 0.5%, turpentine oil 0.6%, aloe powder 0.3%, chlorhexidine hydrochloride 25%, glyceride citrate 0.3%, surplus be go from
Sub- water.
Compared with prior art, the invention proposes a kind of hemodialyzer line clear methods, before dialysis apparatus use
Atomized ozone disinfection treatment is carried out to channel interior, can be kept away in bacterium and the pollutant for using preceding extinction dialysis apparatus channel interior
Exempt from bacterium to cause damages to sufferer in dialysis procedure；After atomized ozone disinfection treatment, physiological saline is accessed, sky can be discharged
Gas is dialysed by pre-processing to pipeline inner wall convenient for subsequent；After dialysis, add water using internal thimerosal
After dilution, it is rinsed and flows immersion, the ingredient in internal thimerosal can effectively remove the calcium and magnesium compound in pipe, can be with pipe
Organic matter in road dissolves each other, and organic matter is discharged；It rinses after impregnating, carries out atomized ozone disinfection treatment again, can effectively remove
Bacterium in pipe, avoids infection；Finally pipeline outer wall is cleaned, line clear can be kept pollution-free；During cleaning, nothing
Pipeline need to be dismantled, can avoid causing secondary pollution to pipeline in installation process after the cleaning；Easy to operate, required material is simple
It is easy to get, cost is relatively low, is worthy to be popularized.
Specific embodiment
Combined with specific embodiments below the present invention is made further to explain, it is clear that described embodiment is only this hair
Bright a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not having
Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
Embodiment one
The present invention provides a kind of hemodialyzer line clear method, comprising the following steps:
S1. before haemodialysis starts, cleaning-sterilizing is carried out to pipeline；
S2. the preparation of ozone: gas source is sent into ozone generator by gas source pipe；Ozone generator is generated by quartz burner
Ultraviolet light be irradiated to the air in spiral gas storehouse, make its generate ozone；
S3. the preparation of atomized water: by ultrasonic ultrasonic delay line memory to the water containing thimerosals such as hydrogen peroxide from liquid feeding bottle into
Row atomization；
S4. the ozone prepared in atomized water obtained in step S3 and step S2 is mixed into and is disappeared containing ozone and hydrogen peroxide etc.
The water mist of noxious material；
S5. it is not necessarily to dismantle the pipeline of hemodialyzer, directly closes dialysis liquid pipeline, other pipelines is kept normally to be connected to, it will be upper
It states water mist and Medical Devices pipeline is sent by snorkel, and the tail gas containing ozone being discharged from pipeline is made to enter gas-liquid separator
It is separated, liquid enters liquid-collecting bottle by tapping valve, and gas is sent to air bag by pipeline and collects；
S6. by water mist obtained in step S4 by connecting with dialysis apparatus pipeline one end in step S5, and make to be discharged from pipeline
The tail gas containing ozone enter gas-liquid separator and separated, liquid enters liquid-collecting bottle by tapping valve, and gas passes through pipeline
It is sent to air bag collection；
S7. after sanitized, ozone generator and atomizer stop working, at this moment, in dialysis apparatus pipeline also remain water mist and
Ozone, booster pump, which works on, sucks air, and after the air of sucking is filtered, dry and clean air is by stopping
The ozone generator only to work enters atomizer, is then entered in dialysis apparatus pipeline by snorkel, and water mist and ozone are discharged；
S8. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline flows in pipeline
It is logical, the air in pipeline is discharged, dialysis liquid pipeline is then opened, after dialysis pipeline carries out a circulation, start formally into
Row haemodialysis；
S9. after the completion of haemodialysis, dialysis liquid pipeline is closed, physiological saline is continued to one circulation of circulation in pipeline, then
It is added after 30 times of reverse osmosis water mixed diluting using internal thimerosal and is heated to 80 DEG C to pipeline progress repeated flushing 15 minutes, then made
Flowing is carried out again with the inside thimerosal 25 after adding reverse osmosis water to dilute to impregnate 30 minutes, internal thimerosal by following volume ratio at
Divide mixing composition: polyoxyethylene alkylphenyl ether 2%, citric acid 25%, lactic acid 5%, malic acid 20%, surplus are deionized water；
S10. after impregnating, the water mist containing the disinfecting substances such as ozone and hydrogen peroxide in step S4 is accessed, is made from pipeline
The tail gas containing ozone of discharge enters gas-liquid separator and is separated, and liquid enters liquid-collecting bottle by tapping valve, and gas passes through
Pipeline is sent to air bag collection；
S11. after the inside thimerosal in pipeline being completely exhausted out, ozone generator and atomizer stop working, at this moment, dialysis apparatus
Also remain water mist and ozone in pipeline, booster pump, which works on, sucks air, dry after the air of sucking is filtered
And clean air enters atomizer by the ozone generator to stop working, then enters dialysis apparatus pipeline by snorkel
It is interior, water mist and ozone are discharged；
S12. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline is in pipeline
Air in pipeline is discharged circulation；
S13. after channel interior cleaning, be diluted with water rear detergent line outer wall using external disinfection liquid, external disinfection liquid by
The ingredient of following volume ratio mixes composition: kefir milk element 0.5%, turpentine oil 0.6%, aloe powder 0.3%, chlorhexidine hydrochloride 25%, lemon
Acid glyceride 0.3%, surplus are deionized water.
Embodiment two
The present invention provides a kind of hemodialyzer line clear method, comprising the following steps:
S1. before haemodialysis starts, cleaning-sterilizing is carried out to pipeline；
S2. the preparation of ozone: gas source is sent into ozone generator by gas source pipe；Ozone generator is generated by quartz burner
Ultraviolet light be irradiated to the air in spiral gas storehouse, make its generate ozone；
S3. the preparation of atomized water: by ultrasonic ultrasonic delay line memory to the water containing thimerosals such as hydrogen peroxide from liquid feeding bottle into
Row atomization；
S4. the ozone prepared in atomized water obtained in step S3 and step S2 is mixed into and is disappeared containing ozone and hydrogen peroxide etc.
The water mist of noxious material；
S5. it is not necessarily to dismantle the pipeline of hemodialyzer, directly closes dialysis liquid pipeline, other pipelines is kept normally to be connected to, it will be upper
It states water mist and Medical Devices pipeline is sent by snorkel, and the tail gas containing ozone being discharged from pipeline is made to enter gas-liquid separator
It is separated, liquid enters liquid-collecting bottle by tapping valve, and gas is sent to air bag by pipeline and collects；
S6. by water mist obtained in step S4 by connecting with dialysis apparatus pipeline one end in step S5, and make to be discharged from pipeline
The tail gas containing ozone enter gas-liquid separator and separated, liquid enters liquid-collecting bottle by tapping valve, and gas passes through pipeline
It is sent to air bag collection；
S7. after sanitized, ozone generator and atomizer stop working, at this moment, in dialysis apparatus pipeline also remain water mist and
Ozone, booster pump, which works on, sucks air, and after the air of sucking is filtered, dry and clean air is by stopping
The ozone generator only to work enters atomizer, is then entered in dialysis apparatus pipeline by snorkel, and water mist and ozone are discharged；
S8. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline flows in pipeline
It is logical, the air in pipeline is discharged, dialysis liquid pipeline is then opened, after dialysis pipeline carries out a circulation, start formally into
Row haemodialysis；
S9. after the completion of haemodialysis, dialysis liquid pipeline is closed, physiological saline is continued to one circulation of circulation in pipeline, then
It is added after 30 times of reverse osmosis water mixed diluting using internal thimerosal and is heated to 80 DEG C to pipeline progress repeated flushing 15 minutes, then made
Flowing is carried out again with the inside thimerosal 25 after adding reverse osmosis water to dilute to impregnate 30 minutes, internal thimerosal by following volume ratio at
Divide mixing composition: polyoxyethylene alkylphenyl ether 5%, citric acid 35%, lactic acid 7%, malic acid 20%, surplus are deionized water；
S10. after impregnating, the water mist containing the disinfecting substances such as ozone and hydrogen peroxide in step S4 is accessed, is made from pipeline
The tail gas containing ozone of discharge enters gas-liquid separator and is separated, and liquid enters liquid-collecting bottle by tapping valve, and gas passes through
Pipeline is sent to air bag collection；
S11. after the inside thimerosal in pipeline being completely exhausted out, ozone generator and atomizer stop working, at this moment, dialysis apparatus
Also remain water mist and ozone in pipeline, booster pump, which works on, sucks air, dry after the air of sucking is filtered
And clean air enters atomizer by the ozone generator to stop working, then enters dialysis apparatus pipeline by snorkel
It is interior, water mist and ozone are discharged；
S12. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline is in pipeline
Air in pipeline is discharged circulation；
S13. after channel interior cleaning, be diluted with water rear detergent line outer wall using external disinfection liquid, external disinfection liquid by
The ingredient of following volume ratio mixes composition: kefir milk element 0.5%, turpentine oil 0.6%, aloe powder 0.3%, chlorhexidine hydrochloride 25%, lemon
Acid glyceride 0.3%, surplus are deionized water.
The invention proposes a kind of hemodialyzer line clear methods, carry out mist to channel interior using preceding in dialysis apparatus
Change ozonization processing, bacterium can be avoided in dialysis procedure in bacterium and the pollutant for using preceding extinction dialysis apparatus channel interior
In cause damages to sufferer；After atomized ozone disinfection treatment, physiological saline is accessed, air can be discharged, by pipeline inner wall
It is pre-processed, is dialysed convenient for subsequent；After dialysis, after being diluted with water using internal thimerosal, be rinsed and
Flowing is impregnated, and the ingredient in internal thimerosal can effectively remove the calcium and magnesium compound in pipe, can be dissolved each other with the organic matter in pipeline,
Organic matter is discharged；It rinses after impregnating, carries out atomized ozone disinfection treatment again, can effectively remove the bacterium in pipe, avoid feeling
Dye；Finally pipeline outer wall is cleaned, line clear can be kept pollution-free；During cleaning, without being dismantled to pipeline, it can keep away
Exempt to cause secondary pollution to pipeline in installation process after the cleaning；Easy to operate, required material is simple and easy to get, and cost is relatively low, value
It must promote.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (5)
1. a kind of hemodialyzer line clear method, which comprises the following steps:
S1. before haemodialysis starts, cleaning-sterilizing is carried out to pipeline；
S2. the preparation of ozone: gas source is sent into ozone generator by gas source pipe；Ozone generator is generated by quartz burner
Ultraviolet light be irradiated to the air in spiral gas storehouse, make its generate ozone；
S3. the preparation of atomized water: by ultrasonic ultrasonic delay line memory to the water containing thimerosals such as hydrogen peroxide from liquid feeding bottle into
Row atomization；
S4. the ozone prepared in atomized water obtained in step S3 and step S2 is mixed into and is disappeared containing ozone and hydrogen peroxide etc.
The water mist of noxious material；
S5. it is not necessarily to dismantle the pipeline of hemodialyzer, directly closes dialysis liquid pipeline, other pipelines is kept normally to be connected to, it will be upper
It states water mist and Medical Devices pipeline is sent by snorkel, and the tail gas containing ozone being discharged from pipeline is made to enter gas-liquid separator
It is separated, liquid enters liquid-collecting bottle by tapping valve, and gas is sent to air bag by pipeline and collects；
S6. by water mist obtained in step S4 by connecting with dialysis apparatus pipeline one end in step S5, and make to be discharged from pipeline
The tail gas containing ozone enter gas-liquid separator and separated, liquid enters liquid-collecting bottle by tapping valve, and gas passes through pipeline
It is sent to air bag collection；
S7. after sanitized, ozone generator and atomizer stop working, at this moment, in dialysis apparatus pipeline also remain water mist and
Ozone, booster pump, which works on, sucks air, and after the air of sucking is filtered, dry and clean air is by stopping
The ozone generator only to work enters atomizer, is then entered in dialysis apparatus pipeline by snorkel, and water mist and ozone are discharged；
S8. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline flows in pipeline
It is logical, the air in pipeline is discharged, dialysis liquid pipeline is then opened, after dialysis pipeline carries out a circulation, start formally into
Row haemodialysis；
S9. after the completion of haemodialysis, dialysis liquid pipeline is closed, physiological saline is continued to one circulation of circulation in pipeline, then
It is heated to 80 DEG C after adding reverse osmosis water to dilute using internal thimerosal to carry out pipeline repeated flushing 15 minutes, reuses and adds reverse osmosis water
Inside thimerosal after dilution carries out flowing and impregnates 30 minutes, and internal thimerosal is made of the ingredient mixing of following volume ratio: poly-
Ethylene oxide alkyl phenylate 0.5~5%, citric acid 10~50%, lactic acid 4~8%, malic acid 10~30%, surplus are deionized water；
S10. after impregnating, the water mist containing the disinfecting substances such as ozone and hydrogen peroxide in step S4 is accessed, is made from pipeline
The tail gas containing ozone of discharge enters gas-liquid separator and is separated, and liquid enters liquid-collecting bottle by tapping valve, and gas passes through
Pipeline is sent to air bag collection；
S11. after the inside thimerosal in pipeline being completely exhausted out, ozone generator and atomizer stop working, at this moment, dialysis apparatus
Also remain water mist and ozone in pipeline, booster pump, which works on, sucks air, dry after the air of sucking is filtered
And clean air enters atomizer by the ozone generator to stop working, then enters dialysis apparatus pipeline by snorkel
It is interior, water mist and ozone are discharged；
S12. after water mist and ozone are discharged, by configured physiological saline and dialysis apparatus piping connection, physiological saline is in pipeline
Air in pipeline is discharged circulation；
S13. after channel interior cleaning, be diluted with water rear detergent line outer wall using external disinfection liquid, external disinfection liquid by
The ingredient of following volume ratio mixes composition: kefir milk element 0.4~0.6%, turpentine oil 0.4~0.8%, aloe powder 0.3~0.4%, hydrochloric acid
Chlorohexidene 15~30%, glyceride citrate 0.3~0.4%, surplus are deionized water.
2. a kind of hemodialyzer line clear method according to claim 1, which is characterized in that the internal thimerosal
It is made of the ingredient mixing of following volume ratio: polyoxyethylene alkylphenyl ether 2~4%, citric acid 20~40%, lactic acid 5~7%, apple
Acid 15~25%, surplus are deionized water.
3. a kind of hemodialyzer line clear method according to claim 1, which is characterized in that the internal thimerosal
It is made of the ingredient mixing of following volume ratio: polyoxyethylene alkylphenyl ether 4~5%, citric acid 30~50%, lactic acid 6~8%, apple
Acid 20~30%, surplus are deionized water.
4. a kind of hemodialyzer line clear method according to claim 1, which is characterized in that rushed in the step S9
The inside thimerosal and reverse osmosis water used when washing is mixed according to the ratio of 1:29, the inside thimerosal and reverse osmosis water that when immersion uses
It is mixed according to the ratio of 1:24.
5. a kind of hemodialyzer line clear method according to claim 1, which is characterized in that the external disinfection liquid
It is made of the ingredient mixing of following volume ratio: kefir milk element 0.5%, turpentine oil 0.6%, aloe powder 0.3%, chlorhexidine hydrochloride 25%, lemon
Lemon acid glyceride 0.3%, surplus are deionized water.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113891732A (en) * | 2019-05-28 | 2022-01-04 | 日机装株式会社 | Blood purification device |
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