CN109528910A - A kind of gynaecology's bacteriostatic gel and preparation method - Google Patents
A kind of gynaecology's bacteriostatic gel and preparation method Download PDFInfo
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- CN109528910A CN109528910A CN201910029819.3A CN201910029819A CN109528910A CN 109528910 A CN109528910 A CN 109528910A CN 201910029819 A CN201910029819 A CN 201910029819A CN 109528910 A CN109528910 A CN 109528910A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/38—Silver; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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Abstract
The invention belongs to medical technical field, a kind of gynaecology's bacteriostatic gel and preparation method are disclosed；Gynaecology's bacteriostatic gel is made of aloe stoste, peppermint, nano silver, purified water, Triclosan, carbomer, triethanolamine.After each Plant Extracts are mixed, 22min, mixing speed 4800rpm are stirred at 55 DEG C；It is cooled to room temperature to solution obtained by upper step, nano silver, gel-type vehicle is added, stir 35min, mixing speed 440rpm；Walk upwards and Triclosan extract and nano silver be added in mixed solution obtained, stir 10min, mixing speed be 890rpm to get.The present invention is suitable for the antibacterial of female private part discomfort, has good cleaning-nursing effect；There is good inhibiting effect to staphylococcus aureus, Escherichia coli, Candida albicans.Gynaecology's bacteriostatic gel of the present invention is quick, saves the time, effectively mitigates patients ' psychological burden.
Description
Technical field
The invention belongs to medical technical field more particularly to a kind of gynaecology's bacteriostatic gel and preparation methods.
Background technique
Currently, the prior art commonly used in the trade is such that
The disease of female reproductive system is gynecological disease, including vulva disease, vaginal disease, uterine disease, fallopian tubal
Disease, disease of ovary etc..Gynecological disease is women common disease, frequently-occurring disease.But since many people are due to gynecological disease shortage
Understanding lacks the health care to body, and various bad life habits etc., make physiological health go from bad to worse in addition, lead to some women
It is eaten up with illness, and obstinate, it is greatly inconvenient to come to normal life, work belt.Gynecological disease is mainly due to women's
Caused by the factors such as physiological structure, sanitation degree and living and working environment, so that women is subjected to Staphylococcus aureus
The favor of bacterium, Escherichia coli, Candida albicans according to statistics in China adult female, has more than 60% or more crowd and often suffers from
There is different degrees of gynecological disease, influence personal image, serious person directly affects normal study, work and life, gives women
Friend took carrys out great suffering.
The antibacterial drug of existing gynaecology is relatively more, generally based on oral western medicine, by a series of absorption of human body, blood
Liquid circulation just reaches affected part, plays bacteriostasis, so that drug effect cannot fully play, so taking effect slowly, increases patient
Psychological burden；Additionally there is lotion, suppository etc., drug effect is poor, it cannot quickly and effectively play its effect, delay treatment,
Such as suppository absorption is slower, has apparent foreign body sensation when patient uses, causes Psychological inadaptability.
In conclusion problem of the existing technology is:
(1) the antibacterial drug of existing gynaecology is relatively more, generally based on oral western medicine, by a series of suction of human body
Receipts, blood circulation just reach affected part, play bacteriostasis, so that drug effect cannot fully play, so taking effect slowly, increase
Patients ' psychological burden；
(2) also there is lotion, suppository etc. in the prior art, drug effect is poor, cannot quickly and effectively play its effect, prolong
Misdiagnosis is treated, such as suppository absorption is slower, has apparent foreign body sensation when patient uses, causes Psychological inadaptability.
Summary of the invention
In view of the problems of the existing technology, the present invention provides a kind of gynaecology's bacteriostatic gel and preparation methods.
The invention is realized in this way a kind of gynaecology's bacteriostatic gel is according to mass fraction by aloe stoste 20%, peppermint
3%, nano silver 350ug/ml, Triclosan 0.25%, carbomer 2%, triethanolamine 1.5%, purified water (remove it
It is appropriate after it) composition.
Further, Triclosan is 0.20%~0.29%.
Another object of the present invention is to provide a kind of preparation methods of gynaecology's bacteriostatic gel, specifically includes the following steps:
Step 1: after each Plant Extracts are mixed, 22min, mixing speed 4800rpm are stirred at 55 DEG C；
Step 2: being cooled to room temperature to solution obtained by upper step, and nano silver, gel-type vehicle is added, and stirs 35min, stirs
Mixing speed is 440rpm；
Step 3: it walks Triclosan extract and nano silver, stirring are added in mixed solution obtained upwards
10min, mixing speed be 890rpm to get.
Further, in step 4, filling is 1~3mL/ pipe.
Another object of the present invention is to provide a kind of application methods of gynaecology's bacteriostatic gel, specifically include:
(1) preceding cleaning vulva is used；
(2) it lies low naturally, buttocks is padded, and gel tube is gently sent into vagina depths, and after gel all injection, extracting will
Gel tube abandons, once a day, one every time.
In conclusion advantages of the present invention and good effect are as follows:
The present invention is suitable for the antibacterial of female private part discomfort, has good cleaning-nursing effect；The present invention is to golden yellow
Staphylococcus, Escherichia coli, Candida albicans have good inhibiting effect.Gynaecology's bacteriostatic gel provided by the invention takes effect
Fastly, it saves the time, no foreign body sensation effectively mitigates patients ' psychological burden.
Endometrium fragment and the menstrual period extravasated blood etc. that 12% or so do not empty are remained for menstrual period rubbish, after menstrual period.It is raw
Produce rubbish, the amniotic fluid that do not cleared up completely after production, lochia, Placenta remnants etc..Sexual life rubbish, sperm, male sex organ packet
Scurf and sheath lubricating fluid residual etc..It is metabolized rubbish, the necrotic tissue residual etc. of uterus metabolism discharge.So the present invention has
There is following effect: (1) cleaning, bacterio static itching-relieving removes odors, aloe extract, calm anti-inflammatory, salubrious antipruritic；PH value is 5, temperature
With it is non-stimulated, make skin more aobvious tender while maintaining privates acid-base balance.(2) antibacterial, large intestine can be effectively suppressed in nano silver
The harmful microorganisms such as bacillus, Candida albicans can dispel privates peculiar smell, women is allowed to regain health.(3) compact, triethanolamine, benefit
The peculiar Chinese medicine preparation that Brittle Falsepimpernel Herb develops, dispelling abnormal flavor, privates lasting；Vaginal relaxation, dry and astringent can be repaired, makes privates compact such as
Just, increase woman charm, improve love life quality.
Detailed description of the invention
Fig. 1 is the preparation method flow chart of gynaecology's bacteriostatic gel provided in an embodiment of the present invention.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Gynaecology's bacteriostatic gel provided in an embodiment of the present invention is according to mass fraction by aloe stoste 20%, peppermint 3%, nanometer
Silver-colored 350ug/ml, Triclosan 0.25%, carbomer 2%, triethanolamine 1.5%, purified water (remove other later suitable
Amount) composition.
Triclosan provided in an embodiment of the present invention is 0.20%~0.29%.
Application principle of the invention is further elaborated with reference to the accompanying drawing；
As shown in Figure 1, the preparation method of gynaecology's bacteriostatic gel provided in an embodiment of the present invention, specifically includes the following steps:
S101: after each Plant Extracts are mixed, 22min, mixing speed 4800rpm are stirred at 55 DEG C；
S102: being cooled to room temperature to solution obtained by upper step, and nano silver, gel-type vehicle is added, and stirs 35min, stirring
Speed is 440rpm；
S103: it walks Triclosan extract and nano silver, stirring are added in mixed solution obtained upwards
10min, mixing speed be 890rpm to get.
The application method of gynaecology's bacteriostatic gel provided in an embodiment of the present invention, specifically includes:
(1) preceding cleaning vulva is used；
(2) it lies low naturally, buttocks is padded, and gel tube is gently sent into vagina depths, and after gel all injection, extracting will
Gel tube abandons, once a day, one every time.
Use scope provided in an embodiment of the present invention: antibacterial, the cleaning-nursing for female private part discomfort.
Application principle of the invention is further described below with reference to specific Pharmacological Analysis；
Aloe sterilization is anti-inflammatory, removing toxic substances, promotes to let out under wound healing, stomach invigorating.
There is peppermint dispelling wind and heat from the body, head clearing, relieving sore-throat to examine thoroughly, soothing the liver promoting the circulation of qi effect, mainly control anemopyretic cold, warm disease at the beginning of
It rises, headache due to pathogenic wind-heat, the more tears of hot eyes, abscess of throat, measles without adequate eruption, rubella itch, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest and other effects.
Nano silver (Nano Silver) is exactly that partial size is accomplished to nanoscale metallic silver simple substance.Nano silver partial size exists mostly
25 rans have strong inhibition and killing to the tens of kinds of pathogenic microorganisms such as Escherichia coli, gonococcus, chlamydia trachomatis
Effect, and drug resistance will not be generated.The quilted stockings made of nano silver and combing cotton fibre has the effect of good antibacterial deodourizing
Fruit.
Triclosan, be used for efficient medicated soap (sanitary perfumed soap), sanitary lotion), except underarm odor (foot aerosol), disinfection
Hand cleanser, wound disinfection spray, medical apparatus sterilizing agent, hygienic facial cleanser (cream), air freshener and deodorant for refrigerator etc.,
It is also used for the arrangement of hygiene tissue and the preservative treatment of plastics, the gram force grace of higher purity is also widely used in treatment gingivitis, tooth
In the curative effect toothpaste and mouthwash of Zhou Yan and canker sore etc., it is proposed that the use of concentration is 0.05%~0.3%.
Card wave is also referred to as carbomer (carbomer), is that the acrylic acid crosslinking being crosslinked with pentaerythrite etc. with acrylic acid is set
Rouge is a kind of very important rheology control agent, and the card wave after neutralization is outstanding gel-type vehicle, has thickening, suspension etc. important
Purposes, simple process, stability is good, is widely used in lotion, cream, in gel.
Triethanolamine, triethanolamine oleate Chinese nickname English name tomelukast English alias Tomelukast；1-
[2-hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)butoxy]phenyl]ethanone；
Tomelukastum；318.37100 physico-chemical property of CAS 88107-10-2 molecular formula C16H22N4O3 molecular weight: refractive index
The purposes of 1.574 288.3 DEG C of flash-point density 1.22g/cm3 553 DEG C of triethanolamine oleates of boiling point: matching as metal cleaner
System, also serves as fiber softening management, makes product good luster, soft.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (5)
1. a kind of gynaecology's bacteriostatic gel, which is characterized in that gynaecology's bacteriostatic gel according to mass fraction by aloe stoste 20%,
Peppermint 3%, nano silver 350ug/ml, Triclosan 0.25%, carbomer 2%, triethanolamine 1.5%, purified water group
At.
2. gynaecology's bacteriostatic gel as described in claim 1, which is characterized in that the Triclosan be 0.20%~
0.29%.
3. a kind of preparation method of gynaecology's bacteriostatic gel as described in claim 1, which is characterized in that gynaecology's bacteriostatic gel
Preparation method, specifically includes the following steps:
Step 1: after each Plant Extracts are mixed, 22min, mixing speed 4800rpm are stirred at 55 DEG C；
Step 2: being cooled to room temperature to solution obtained by upper step, and nano silver, gel-type vehicle is added, and stirs 35min, stirring speed
Degree is 440rpm；
Step 3: walking in mixed solution obtained upwards and Triclosan extract and nano silver be added, stir 10min,
Mixing speed be 890rpm to get.
4. the preparation method of gynaecology's bacteriostatic gel as claimed in claim 3, which is characterized in that in the step 4, filling is 1
~3mL/ pipe.
5. a kind of application method of gynaecology's bacteriostatic gel as described in claim 1, which is characterized in that gynaecology's bacteriostatic gel
Application method, specifically include:
(1) preceding cleaning vulva is used；
(2) it lies low naturally, buttocks is padded, and gel tube is gently sent into vagina depths, after gel all injection, extracts gel
Pipe abandons, once a day, one every time.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910029819.3A CN109528910A (en) | 2019-01-14 | 2019-01-14 | A kind of gynaecology's bacteriostatic gel and preparation method |
Applications Claiming Priority (1)
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|---|---|---|---|
| CN201910029819.3A CN109528910A (en) | 2019-01-14 | 2019-01-14 | A kind of gynaecology's bacteriostatic gel and preparation method |
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| Publication Number | Publication Date |
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| CN109528910A true CN109528910A (en) | 2019-03-29 |
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| CN201910029819.3A Withdrawn CN109528910A (en) | 2019-01-14 | 2019-01-14 | A kind of gynaecology's bacteriostatic gel and preparation method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111420017A (en) * | 2020-04-21 | 2020-07-17 | 新疆月之女生物科技有限公司 | Gynecological antibacterial liquid and preparation method thereof |
| CN113813442A (en) * | 2021-09-29 | 2021-12-21 | 王旺盛 | Artemisia desertorum gum antibacterial gel formula |
-
2019
- 2019-01-14 CN CN201910029819.3A patent/CN109528910A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111420017A (en) * | 2020-04-21 | 2020-07-17 | 新疆月之女生物科技有限公司 | Gynecological antibacterial liquid and preparation method thereof |
| CN113813442A (en) * | 2021-09-29 | 2021-12-21 | 王旺盛 | Artemisia desertorum gum antibacterial gel formula |
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Application publication date: 20190329 |