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CN109394934A - A kind of book on Chinese herbal medicine cream - Google Patents

A kind of book on Chinese herbal medicine cream Download PDF

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Publication number
CN109394934A
CN109394934A CN201811395148.4A CN201811395148A CN109394934A CN 109394934 A CN109394934 A CN 109394934A CN 201811395148 A CN201811395148 A CN 201811395148A CN 109394934 A CN109394934 A CN 109394934A
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CN
China
Prior art keywords
parts
radix
coarse powder
radix angelicae
liquid
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Application number
CN201811395148.4A
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Chinese (zh)
Inventor
徐方岭
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Shandong Shenming Biotechnology Co Ltd
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Shandong Shenming Biotechnology Co Ltd
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Priority to CN201811395148.4A priority Critical patent/CN109394934A/en
Publication of CN109394934A publication Critical patent/CN109394934A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125Camphor; Nuclear substituted derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/264Aristolochia (Dutchman's pipe)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention proposes a kind of herbal cream, its raw material includes following components by weight: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus, after medical fluid enters body, it is big to be absorbed area, dissolution rate is high, to both ensure that whole effective components of drug, the dose requirements that must reach of Chinese medicine treatment disease are in turn ensured, so showing therapeutic effect more better than capsule, pill;A certain amount of alcohol is added in the formulation, that is, ensure that medical fluid never degenerates, while inducting the medicines into affected channel, promoting blood circulation, row drug effect had not only guaranteed medical fluid not Biodeterioration, but also promoted the effect of medicine.

Description

A kind of book on Chinese herbal medicine cream
Technical field
The present invention relates to liquid medicine technical field is applied with, specially a kind of herbal cream (liquid).
Background technique
As rhythm of life is accelerated, pressure increases, there is sub-health state in the body of people, and resistance is poor, be easy to cause Numb limb, the symptoms such as joint, lumbocrural pain, blockage of main and collateral channels, protrusion of lumber intervertebral disc, sciatica, scapulohumeral periarthritis, cervical spondylosis; Occur some liquid medicine for preventing and treating rheumatism on the market at present, have for oral administration and external application, the medicinal liquor for rheumatism of external application is to absolutely mostly Several crowds is applicable in, but its is ineffective, and be easy to cause skin damage.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the existing defects, provides a kind of herbal cream (liquid), and liquid enters quilt after body Absorption area is big, and dissolution rate is high, to both ensure that whole effective components of drug, in turn ensures the institute of Chinese medicine treatment disease The dose requirements that must reach, so showing therapeutic effect more better than capsule, pill;A certain amount of wine is added in the formulation Essence ensure that medical fluid never degenerates, while inducting the medicines into affected channel, promoting blood circulation, row drug effect, not only guarantee medical fluid not Biodeterioration, but also promote The effect of medicine can effectively solve the problems in background technique.
To achieve the above object, the present invention proposes: a kind of book on Chinese herbal medicine cream (liquid), raw material includes following components by weight: 15.5-17.6 parts of safflower, 12.5-18.9 parts of peach kernel, 5.2-8.9 parts of Radix Astragali, 12.2-15.8 parts of lopseed, radix saposhnikoviae 17.9-19.2 Part, 15.2-18.9 parts of myrrh, 12.5-19.2 parts of berba aristolochiae mollissimae, 10.2-15.2 parts of Radix Angelicae Pubescentis, 15.6-18.9 parts of Qin Jiu, Rhizoma Et Radix Notopterygii 10.2-15.9 parts, 4.5-6.8 parts of Radix Angelicae Sinensis, 6.8-12.9 parts of camphor, 6.9-9.3 parts of pheretima, 5.6-7.9 parts of cortex cinnamomi, agkistrodon 10.7-13.7 parts, 15.6-19.6 parts of Sanguis Draxonis, 14.6-17.3 parts of Moschus.
It further include 400.5-550.5 parts of alcohol as a preferred technical solution of the present invention.
The present invention also provides a kind of preparation methods of herbal cream (liquid), comprising the following steps:
S1): stock: weighing by recipe ratio by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, the Qin Nine, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, injected in three immersion bottles Alcohol, alcohol are totally submerged coarse powder, impregnate bottle lidstock 5-9 days;
S4) filtering mixing: the solution in bottle is impregnated by three, three kinds of filtered fluids and three kinds of filter residues are obtained by filtration, and by three kinds Filtered fluid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
As a preferred technical solution of the present invention, the degree of alcohol is 55-70%.
As a preferred technical solution of the present invention, environment temperature where impregnating bottle lidstock is 10-15 DEG C.
As a preferred technical solution of the present invention, precipitating reagent is tricalcium phosphate or atlapulgite.
As a preferred technical solution of the present invention, when filtering, the aperture of strainer is 50-100 μm.
Compared with prior art, the beneficial effects of the present invention are: medical fluid enters to be absorbed after body, area is big, and dissolution rate is high, To both ensure that whole effective components of drug, the dose requirements that must reach of Chinese medicine treatment disease, institute are in turn ensured To show therapeutic effect more better than capsule, pill;A certain amount of alcohol is added in the formulation, that is, ensure that medical fluid is constant Matter, while inducting the medicines into affected channel, promoting blood circulation, row drug effect had not only guaranteed medical fluid not Biodeterioration, but also have promoted the effect of medicine.
Detailed description of the invention
Fig. 1 is a kind of preparation method flow chart of herbal cream (liquid) of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, the present invention the following technical schemes are provided:
Embodiment one:
A kind of book on Chinese herbal medicine cream (liquid), raw material includes following components by weight: 15.5 parts of safflower, 12.5 parts of peach kernel, Radix Astragali 5.2 parts, 12.2 parts of lopseed, radix saposhnikoviae 17.9 parts, 15.2 parts of myrrh, 12.5 parts of berba aristolochiae mollissimae, 10.2 parts of Radix Angelicae Pubescentis, 15.6 parts of Qin Jiu, 10.2 parts of Rhizoma Et Radix Notopterygii, 4.5 parts of Radix Angelicae Sinensis, 6.8 parts of camphor, 6.9 parts of pheretima, 5.6 parts of cortex cinnamomi, 10.7 parts of agkistrodon, Sanguis Draxonis 15.6 Part, 14.6 parts of Moschus, 400.5 parts of alcohol.
The present invention also provides a kind of preparation methods of herbal cream (liquid), comprising the following steps:
S1): stock: weighing by recipe ratio by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, the Qin Nine, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, injected in three immersion bottles Alcohol, alcohol are totally submerged coarse powder, impregnate bottle lidstock 5-9 days;
S4) filtering mixing: the solution in bottle is impregnated by three, three kinds of filtered fluids and three kinds of filter residues are obtained by filtration, and by three kinds Filtered fluid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
The degree of alcohol is 55%.
Environment temperature where impregnating bottle lidstock is 10-15 DEG C.
Precipitating reagent is tricalcium phosphate or atlapulgite.
When filtering, the aperture of strainer is 50 μm.
Embodiment two:
16.2 parts of safflower, 14.6 parts of peach kernel, 6.7 parts of Radix Astragali, 13.5 parts of lopseed, radix saposhnikoviae 18.2 parts, 17.2 parts of myrrh, 14.9 parts of berba aristolochiae mollissimae, 12.1 parts of Radix Angelicae Pubescentis, 16.7 parts of Qin Jiu, 13.4 parts of Rhizoma Et Radix Notopterygii, 5.6 parts of Radix Angelicae Sinensis, 9.3 parts of camphor, 7.3 parts of pheretima, 6.1 parts of cortex cinnamomi, 11.4 parts of agkistrodon, 17.5 parts of Sanguis Draxonis, 15.2 parts of Moschus, 450.6 parts of alcohol.
The present invention also provides a kind of preparation methods of herbal cream (liquid), comprising the following steps:
S1): stock: weighing by recipe ratio by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, the Qin Nine, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, injected in three immersion bottles Alcohol, alcohol are totally submerged coarse powder, impregnate bottle lidstock 5-9 days;
S4) filtering mixing: the solution in bottle is impregnated by three, three kinds of filtered fluids and three kinds of filter residues are obtained by filtration, and by three kinds Filtered fluid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
The degree of alcohol is 60%.
Environment temperature where impregnating bottle lidstock is 10-15 DEG C.
Precipitating reagent is tricalcium phosphate or atlapulgite.
When filtering, the aperture of strainer is 50 μm.
Embodiment three:
16.4 parts of safflower, 16.9 parts of peach kernel, 7.8 parts of Radix Astragali, 14.2 parts of lopseed, radix saposhnikoviae 18.5 parts, 17.5 parts of myrrh, 18.2 parts of berba aristolochiae mollissimae, 14.1 parts of Radix Angelicae Pubescentis, 17.5 parts of Qin Jiu, 14.1 parts of Rhizoma Et Radix Notopterygii, 6.2 parts of Radix Angelicae Sinensis, 10.5 parts of camphor, pheretima 8.4 Part, 6.1 parts of cortex cinnamomi, 11.5 parts of agkistrodon, 18.3 parts of Sanguis Draxonis, 116.7 parts of Moschus, 521.4 parts of alcohol.
The present invention also provides a kind of preparation methods of herbal cream (liquid), comprising the following steps:
S1): stock: weighing by recipe ratio by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, the Qin Nine, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, injected in three immersion bottles Alcohol, alcohol are totally submerged coarse powder, impregnate bottle lidstock 5-9 days;
S4) filtering mixing: the solution in bottle is impregnated by three, three kinds of filtered fluids and three kinds of filter residues are obtained by filtration, and by three kinds Filtered fluid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
The degree of alcohol is 65%.
Environment temperature where impregnating bottle lidstock is 10-15 DEG C.
Precipitating reagent is tricalcium phosphate or atlapulgite.
When filtering, the aperture of strainer is 75 μm.
Example IV:
17.6 parts of safflower, 18.9 parts of peach kernel, 8.9 parts of Radix Astragali, 115.8 parts of lopseed, radix saposhnikoviae 19.2 parts, 18.9 parts of myrrh, 19.2 parts of berba aristolochiae mollissimae, 15.2 parts of Radix Angelicae Pubescentis, 18.9 parts of Qin Jiu, 15.9 parts of Rhizoma Et Radix Notopterygii, 6.8 parts of Radix Angelicae Sinensis, 12.9 parts of camphor, pheretima 9.3 Part, 7.9 parts of cortex cinnamomi, 13.7 parts of agkistrodon, 19.6 parts of Sanguis Draxonis, 17.3 parts of Moschus, 550.5 parts of alcohol.
The present invention also provides a kind of preparation methods of herbal cream (liquid), comprising the following steps:
S1): stock: weighing by recipe ratio by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, the Qin Nine, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, injected in three immersion bottles Alcohol, alcohol are totally submerged coarse powder, impregnate bottle lidstock 5-9 days;
S4) filtering mixing: the solution in bottle is impregnated by three, three kinds of filtered fluids and three kinds of filter residues are obtained by filtration, and by three kinds Filtered fluid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
The degree of alcohol is 70%.
Environment temperature where impregnating bottle lidstock is 10-15 DEG C.
Precipitating reagent is tricalcium phosphate or atlapulgite.
When filtering, the aperture of strainer is 100 μm.
Safflower: blood circulation, removing blood stasis and acesodyne belong to the blood-activating and menstruation-regulating medicinal of drug for invigorating blood circulation and eliminating stasis subordinate classification.
Peach kernel: promoting blood circulation, relax bowel and defecation are used for menostasis, dysmenorrhea , wei lump in the abdomen lump in the abdomen, injury from falling down, dry constipation of intestines.
Radix Astragali: sweet in flavor, tepor has the effect of invigorating qi for strengthening superficies, torr sore myogenic, sharp water, cures mainly deficient qi and blood, spontaneous perspiration, long Rush down the diseases such as rectal prolapse, uterine prolapse, ephritis edema, albuminuria, diabetes, chronic ulcer.
Lopseed: wind-dispelling, dehumidifying, relaxing muscles and tendons are invigorated blood circulation, analgesic.Control rheumatic arthralgia, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, ringworm sore is swollen Poison.
Radix saposhnikoviae: it expels pathogenic wind from the body surface, is expel endogenous wind to relieve convulsion, spasmolysis, antipruritic.
Myrrh: blood stasis eliminatings, detumescence ding-tong are dissipated;It controls and falls damage, metal-inflicted wound, muscles and bones, all Tong , Disorder lumps in the abdomen of trusted subordinate, menostasis, ulcer sore pain, Anal fistula, mesh barrier.
Berba aristolochiae mollissimae: dispelling wind and removing obstruction in the meridians, analgesic;For rheumatic arthralgia, stomachache, testiclar gall, the diseases such as injuries from falls as well.
Radix Angelicae Pubescentis: dispelling wind and eliminating dampness, numbness relieving and pain relieving;Belong to the wind-damp-dispelling and cold-dissipating medicinal of medicine for rheumatism subordinate classification.
Qin Jiu: it is used for rheumatic arthralgia, apoplectic dyscinesia, muscle arteries and veins contraction, skeletal pain, afternoon tidal fever, infantile malnutrition generates heat to be wet Hot jaundice.
Rhizoma Et Radix Notopterygii: it is used for rheumatic arthralgia, apoplectic dyscinesia, muscle arteries and veins contraction, skeletal pain, afternoon tidal fever, infantile malnutrition generates heat to be wet Hot jaundice.
Radix Angelicae Sinensis: replenishing and activating blood, menstruction regulating and pain relieving, relax bowel and defecation.
Camphor: have one's ideas straightened out and ward off dirty, dehumidifying desinsection, warming and odynolysis.
Pheretima: heat-clearing arresting convulsion dredging collateral, is relievingd asthma, diuresis.
Cortex cinnamomi: fiery supporing yang, let the fire back to its origin, eliminating cold to stop pain, blood circulation.
Agkistrodon: wind-damp dispelling, saturating muscles and bones, arresting convulsion are jerked.Control rheumatism paralysis, arthralgia.
Kylin: promoting blood circulation to remove blood stasis, analgesic therapy, hemostasia and promoting granulation, sore are exhausted.
Moschus: having one's ideas straightened out, and wards off dirty, dredging collateral, dissipates the stasis of blood.
Patient is using the herbal cream (liquid) of the present invention, and external application affected part is each primary sooner or later, and dose 13ml is applied with 1-3 Month, it is as a result as follows:
Age Number of cases Recovery from illness Effectively It improves In vain Control group Control group improves
18 years old to 35 years old 17 13 2 1 0 17 0
35 years old to 55 years old 55 51 4 0 0 55 0
55 years old or more 45 43 2 0 0 45 0
Benefit of the present invention: after medical fluid enters body, it is big to be absorbed area, and dissolution rate is high, to both ensure that the whole of drug Effective component in turn ensures the dose requirements that must reach of Chinese medicine treatment disease, so showing more preferable than capsule, pill Therapeutic effect;A certain amount of alcohol is added in the formulation, that is, ensure that medical fluid never degenerates, while inducting the medicines into affected channel, promoting blood circulation, row Drug effect had not only guaranteed medical fluid not Biodeterioration, but also has promoted the effect of medicine.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (7)

1. a kind of book on Chinese herbal medicine cream (liquid), which is characterized in that its raw material includes following components by weight: 15.5-17.6 parts of safflower, peach 12.5-18.9 parts of benevolence, 5.2-8.9 parts of Radix Astragali, 12.2-15.8 parts of lopseed, 17.9-19.2 parts of radix saposhnikoviae, myrrh 15.2-18.9 Part, 12.5-19.2 parts of berba aristolochiae mollissimae, 10.2-15.2 parts of Radix Angelicae Pubescentis, 15.6-18.9 parts of Qin Jiu, 10.2-15.9 parts of Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis 4.5- 6.8 parts, 6.8-12.9 parts of camphor, 6.9-9.3 parts of pheretima, 5.6-7.9 parts of cortex cinnamomi, 10.7-13.7 parts of agkistrodon, Sanguis Draxonis 15.6-19.6 14.6-17.3 parts of part, Moschus.
2. a kind of herbal cream (liquid) according to claim 1, it is characterised in that: further include 400.5-550.5 parts of alcohol.
3. a kind of preparation method of book on Chinese herbal medicine cream (liquid), it is characterised in that: the following steps are included:
S1): stock: by recipe ratio weigh by safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae, myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima, osmanthus, agkistrodon, Sanguis Draxonis, Moschus dry substance weigh by weight;
S2 it) crushes: safflower, peach kernel, Radix Astragali, lopseed, radix saposhnikoviae being crushed in pulverizer, obtain coarse powder A;
Myrrh, berba aristolochiae mollissimae, Radix Angelicae Pubescentis, Qin Jiu, Rhizoma Et Radix Notopterygii, Radix Angelicae Sinensis, camphor, pheretima are crushed in pulverizer, obtain coarse powder B;
Cortex cinnamomi, agkistrodon, Sanguis Draxonis, Moschus are crushed in pulverizer, obtain coarse powder C;
S3 it) impregnates: coarse powder A, coarse powder B, coarse powder C being respectively put into three immersion bottles, inject alcohol in three immersion bottles, Alcohol is totally submerged coarse powder, impregnates bottle lidstock 5-9 days;
S4) filtering mixing: three kinds of filtered fluids and three kinds of filter residues are obtained by filtration in the solution that three are impregnated in bottle, and three kinds are filtered Liquid is mixed to get mixed liquor;
S5 it) presses juice: three kinds of filter residues is put into squeezer, pressure juice is added to mixed liquor;
S6 it) precipitates: precipitating reagent stirring being added into mixed liquor, passes through strainer filtering.
4. a kind of preparation method of herbal cream (liquid) according to claim 3, it is characterised in that: the degree of alcohol is 55- 70%.
5. a kind of preparation method of herbal cream (liquid) according to claim 3, it is characterised in that: impregnate bottle lidstock institute It is 10-15 DEG C in environment temperature.
6. a kind of preparation method of herbal cream (liquid) according to claim 3, it is characterised in that: precipitating reagent is tricalcium phosphate Or atlapulgite.
7. a kind of preparation method of herbal cream (liquid) according to claim 3, it is characterised in that: when filtering, the hole of strainer Diameter is 50-100 μm.
CN201811395148.4A 2018-11-22 2018-11-22 A kind of book on Chinese herbal medicine cream Pending CN109394934A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1342462A (en) * 2000-09-08 2002-04-03 何兴峰 Composite medicine for treating rheumatoid arthritis
CN102824393A (en) * 2012-08-19 2012-12-19 甘肃省中医院 Pharmaceutical composition for dispelling wind, relieving pain, dispelling cold, and removing dampness and preparation method thereof
CN104997838A (en) * 2015-07-31 2015-10-28 赵妙元 Rheumatism medical wine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1342462A (en) * 2000-09-08 2002-04-03 何兴峰 Composite medicine for treating rheumatoid arthritis
CN102824393A (en) * 2012-08-19 2012-12-19 甘肃省中医院 Pharmaceutical composition for dispelling wind, relieving pain, dispelling cold, and removing dampness and preparation method thereof
CN104997838A (en) * 2015-07-31 2015-10-28 赵妙元 Rheumatism medical wine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李红: "中药酒浴辅助治疗中风偏瘫25例", 《河南中医》 *
马宽等: "中药透入疗法治疗风湿性关节炎疗效观察", 《中国临床医生》 *

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Application publication date: 20190301