CN109364008A - A kind of multiple-effect moisturiser and preparation method thereof - Google Patents
A kind of multiple-effect moisturiser and preparation method thereof Download PDFInfo
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- CN109364008A CN109364008A CN201811481107.7A CN201811481107A CN109364008A CN 109364008 A CN109364008 A CN 109364008A CN 201811481107 A CN201811481107 A CN 201811481107A CN 109364008 A CN109364008 A CN 109364008A
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- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 10
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- 210000003205 muscle Anatomy 0.000 description 1
- 230000004118 muscle contraction Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000004792 oxidative damage Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 150000008442 polyphenolic compounds Chemical class 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 201000004700 rosacea Diseases 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 125000002640 tocopherol group Chemical group 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 230000010148 water-pollination Effects 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The present invention provides a kind of multiple-effect moisturisers, it contains the following parts by weight: 0.01-3 parts of Flos Buddlejae extract, 0.01-2 parts of blueberry berry extract, 0.01-2 parts of xanthan gum, 0.01-2 parts of citric acid, 0.01-2 parts of gluconolactone, 0.01-2 parts of calcium gluconate, 0.01-5 parts of hylocereus berry extract, 0.01-5 parts of Phenoxyethanol, 0.01-5 parts of sodium pyrosulfite, 0.01-3 parts of leucojum aestivum bulb extract, 0.01-3 parts of extractive of olive growing leaves, 0.1-3 parts of niacinamide, 0.01-2 parts of pomegranate berry extract, 0.01-2 parts of dipalmitoyl hydroxyproline, 0.001-0.5 parts of eryngium maritimum callus tissue culture filtrate etc..The present invention is by the compounding of ingredient in formula so that moisturiser of the invention is provided simultaneously with moisturizing, anti-blue light, reparation, crease-resistant, whitening spot-removing multi-efficiency.
Description
Technical field
The present invention relates to technical field of skin care more particularly to a kind of multiple-effect moisturiser and preparation method thereof.
Background technique
Face cream refers to the white shape cosmetics for playing skin care effect for face or body.It is coated in the face cream meeting of face
Thin film is formed on the skin, prevents skin water loss.With the development of science and technology skin whitening, moisturizing frost is as a kind of skin care
Product occupy sizable specific gravity in the daily life of people especially women.And cream product occupy in skin care item it is important
Status, it be also using earliest, most universal, the maximum cosmetics of volume of production and marketing, moisturiser is most commonly seen one of cream.
It is distinct however, the raw material of cosmetics is various, in order to make the skin whitening, moisturizing frost of production it is more natural, more comprehensively, protect
Wet effect is more preferable, need to be reasonably combined by each raw material, and ratio is appropriate, gives full play to respective effect, continuing care, battalion for face
The reinforcing of supplement and equilibrium function is supported, it is still necessary to further increase.
Summary of the invention
The present invention is to make up the deficiencies in the prior art, provides a kind of while having crease-resistant, oxidation-resisting and caducity, uvioresistant blue
The moisturiser of light, whitening spot-removing multiple efficacies.
To achieve the purpose of the present invention, the technical solution adopted by the present invention are as follows: a kind of multiple-effect moisturiser includes following weight
The component of part: 0.01-3 parts of Flos Buddlejae extract, 0.01-2 parts of blueberry berry extract, 0.01-2 parts of xanthan gum, citric acid 0.01-
2 parts, 0.01-2 parts of gluconolactone, 0.01-2 parts of calcium gluconate, 0.01-5 parts of hylocereus berry extract, Phenoxyethanol 0.01-5
Part, 0.01-5 parts of sodium pyrosulfite, 0.01-3 parts of leucojum aestivum bulb extract, 0.01-3 parts of extractive of olive growing leaves, nicotinoyl
0.1-3 parts of amine, 0.01-2 parts of pomegranate berry extract, 0.01-2 parts of dipalmitoyl hydroxyproline, eryngium maritimum callus tissue culture
0.001-0.5 parts of object filtrate, 0.01-3 parts of nipa palm seed, 0.01-3 parts of ascorbic acid, 0.01-18 parts of skin conditioning agent, emollient
0.2-30 parts, 0.1-68 parts of moisturizer, 0.01-1.4 parts of preservative, 0.05-1 parts of antioxidant, 1-5 parts of emulsifier, stabilizer
0.2-2 parts, 0.01-0.3 parts of essence.
Preferably, the multiple-effect moisturiser, contains the following parts by weight: 0.1-1.5 parts of Flos Buddlejae extract, blueberry
0.25-1 parts of berry extract, 0.25-1 parts of xanthan gum, 0.25-1 parts of citric acid, 0.25-1 parts of gluconolactone, calcium gluconate
0.25-1 parts, 0.5-3 parts of hylocereus berry extract, 0.5-3 parts of Phenoxyethanol, 0.5-3 parts of sodium pyrosulfite, leucojum aestivum bulb
0.1-2 parts of extract, 0.1-2 parts of extractive of olive growing leaves, 0.5-2 parts of niacinamide, 0.15-1 parts of pomegranate berry extract, two palms
0.5-1.8 parts of acyl hydroxyproline, 0.01-1.3 parts of eryngium maritimum callus tissue culture filtrate, 0.1-2 parts of nipa palm seed, Vitamin C
0.01-3 parts sour, 0.01-18 parts of skin conditioning agent, 0.2-30 parts of emollient, 0.1-68 parts of moisturizer, preservative 0.01-1.4
Part, 0.05-1 parts of antioxidant, 1-5 parts of emulsifier, 0.2-2 parts of stabilizer, 0.01-0.3 parts of essence.
Preferably, the skin conditioning agent is selected from ring five dimethyl silicone polymer, the poly- first siloxanes of stearic oxygen, poly- diformazan silicon
Siloxane copolymers, dimethyl silicone polymer, Atlantic Ocean helmet chest porgy oil, Sodium Hyaluronate cross-linked polymer, Sodium Hyaluronate, acetyl
Change one of Sodium Hyaluronate, hydrolysis Sodium Hyaluronate or any combination thereof.
It is highly preferred that the skin conditioning agent contains the following parts by weight: 0.01-3 parts of Atlantic Ocean helmet chest porgy oil,
0.1-5 parts of ring five dimethyl silicone polymers, the poly- first siloxanes of stearic oxygen, dimethione copolymer and dimethyl silicone polymer
Mixture, 0.1-10 parts of Sodium Hyaluronate cross-linked polymers, Sodium Hyaluronate, acetylation Sodium Hyaluronate and hydrolysis hyalomitome
The mixture of sour sodium；Wherein ring five dimethyl silicone polymer, the poly- first siloxanes of stearic oxygen, dimethione copolymer and poly- two
The mixture of methylsiloxane comes from GRANT INDUSTRIES company, the products material of trade name GICD-10；Hyaluronic acid
Sodium cross-linked polymer, Sodium Hyaluronate, acetylation Sodium Hyaluronate and hydrolyze Sodium Hyaluronate mixture from Hua Xifu it is auspicious
Up to company of biological medicine Co., Ltd, the products material of trade name 4D hyaluronic acid.
Preferably, the emollient is selected from one of ring five dimethyl silicone polymer, white pond flower seed oil or combinations thereof.
It is highly preferred that the emollient contains the following parts by weight: 5-25 parts of ring five dimethyl silicone polymer, Bai Chi
0.2-5 parts of flower seed oil.
Preferably, the moisturizer is selected from one of 1,3-PD, butanediol, trehalose, Anjidew NL50 or its any group
It closes.
It is highly preferred that the moisturizer contains the following parts by weight: 2-30 parts of 1,3-PD, butanediol 2-25
Part, 0.1-3 parts of trehalose, 0.1-10 parts of Anjidew NL50.
Preferably, the preservative is selected from one of methyl hydroxybenzoate, Phenoxyethanol, Sensiva SC50 or its any group
It closes.
It is highly preferred that the preservative contains the following parts by weight: 0.01-0.4 parts, 0.05-1 parts benzene of methyl hydroxybenzoate
The mixture of oxyethanol and Sensiva SC50, the mixture come from Schulke Mayr GmbH (German Shu Mei) company, quotient
The name of an article is the raw produce of EUXYL PE 9010.
Preferably, the antioxidant is tocopherol.
Preferably, the emulsifier be ring five dimethyl silicone polymer, PEG/PPG-20/15 dimethyl silicone polymer it is mixed
Object is closed, MOMENTIVE company, the raw produce of trade name SF1540 are come from.
Preferably, the stability is sodium chloride.
Eryngium maritimum callus tissue culture filtrate selected by the present invention is the solonchak plant for being grown on Brittany seashore
The patented product that object is obtained through stem cells technology culture, the complete component containing plant.Rich in flavonoids, amino acid and sugar can
It is used to antioedematous, analgesic and resistance inflammation aging, there is stimulation promoting epidermization, rebuilds epidermis dermis binder course and reduction illumination
The effect of caused stimulation and inflammation.
Butterflybush flower is also known as " butterfly wood ", is originated from plateau plant butterflybush flower, can fight the radiation of highlands strong sunlight, simultaneously
The damage of blue light, infrared light and ultraviolet light to skin is fought, inhibits and repair the generation of damage in each key point of light injury.
Cellular oxidation caused by infrared radiation and ultraviolet radiation can be effectively reduced in polyphenol in blueberry berry extract
Stress reaction reduces free radical quantity, reduces cellular damage.Meanwhile the synthesis of metalloproteinases can be inhibited, weaken collagen egg
White degradation, prevention dermal layer of the skin is impaired, reduces color spot, wrinkle.It can play the role of prevention with repairing light aging.
Hylocereus berry extract is a kind of water solubility slurries obtained in the dragon fruit.Skin can be made to have to harsh environment
Defence effect.Containing dormin ingredient, cell Proliferation can be slowed down, to anti-aging, while it is bright to have had both instant and long-acting whitening
The effect of skin.Further, since its polysaccharide for containing high-content, moreover it is possible to so that skin is kept moisture, improve skin tightness.
Leucojum aestivum bulb extract is the water-soluble plant extracted in a kind of leucojum aestivum bulb from dormant state
Object extract, be capable of rest cell and increase SOD (superoxide dismutase) expression, thus have it is anti-oxidant, slow down aging
The effect of；The effect of brilliant white skin capable of being reached by the breeding and the synthesis of melanin for slowing down melanocyte；It can inhibit nerve
The contraction of muscle in muscle, therefore can be used as " effective creotoxin substitute ".Synthesis reaches anti-aging, crease-resistant and whitening function
Effect.
Nipa palm seed is to slow down cell point from that can survive up to the suspend mode ingredient extracted in date seed in 2000
It splits, while oxidative damage can also be prevented, slow down limited point of ageing process-Hayflick based on two kinds of theories about aging
Rift opinion and Harman free-radical theory, therefore comprehensive can slow down aging；α -2 adrenocepter can be also activated, is promoted
Vessel retraction has effects that anti-irritant of releiving to alleviate black eye and acne rosacea.
Extractive of olive growing leaves olive leaf contains abundant phenolic compound, bitter substance-olive folic acid especially therein, class
Flavones, anthocyanidin, tannic acid etc. have unique and superpower anti-oxidant, anti-inflammatory activity and bacteriostasis efficacy.
The present invention also provides a kind of preparation methods for preparing institute's multiple-effect moisturiser as above, comprising the following steps:
(1) A phase is weighed into emulsion pot, opens homogeneous until substantially uniformity, stirring are after twenty minutes, spare；Wherein A phase raw material
It is poly- including ring five dimethyl silicone polymer, PEG/PPG-20/15 dimethyl silicone polymer, ring five dimethyl silicone polymer, ring five
The poly- first siloxanes of dimethyl siloxane/tristearin oxygen/dimethione copolymer/dimethyl silicone polymer, tocopherol, the Atlantic Ocean
Helmet chest porgy oil, dipalmitoyl hydroxyproline, white pond flower seed oil, pomegranate berry extract, octanoic acid, Triglyceride DDD；
(2) Material in B phase is weighed into water phase, begins to warm up stirring, insulated and stirred 20 minutes；45 DEG C are cooled to, C is added
Phase, D phase, E phase, it is spare after mixing evenly；Wherein B phase raw material include 1,3- propylene glycol, it is Sodium Hyaluronate cross-linked polymer, transparent
Matter acid sodium, acetylation Sodium Hyaluronate, hydrolysis Sodium Hyaluronate, sodium chloride, butanediol, niacinamide, methyl hydroxybenzoate, trehalose,
Anjidew NL50；Wherein C phase raw material includes eryngium maritimum callus tissue culture filtrate, water；Wherein D phase raw material includes butterflybush flower extraction
Object, blueberry berry extract, xanthan gum, citric acid, gluconolactone, calcium gluconate, hylocereus berry extract, leucojum aestivum bulb
Extract, nipa palm seed, extractive of olive growing leaves；Wherein E phase raw material includes Phenoxyethanol, Sensiva SC50, essence；
(3) B phase is slowly pumped into (time control in 30min) under fast stirring, when especially starting revolving speed 2000 with
On, after adding, after stirring 10min；Open homogeneous 1~2 minute, it is fixed depending on consistency；
(4) inspection declaration, qualified discharging are to get multiple-effect moisturiser.
Beneficial effects of the present invention: the present invention is answered by the ingredient with anti-oxidant, anti-blue light, anti-wrinkle white-skinned face function
Match, Dermatochalasia, aging caused by so that moisturiser of the invention is fought because of ultraviolet light, blue light；It is added in formula a variety of dry thin
Born of the same parents' ingredient effectively antagonizes light aging, repairs damage caused by light aging, accelerates metabolism, promote the cutin containing melanin
Cell detachment.The synergy of niacinamide and hylocereus berry extract: reach long-acting and instant skin lightening and combine；Addition is more simultaneously
Kind is anti-inflammatory, antipathogenic composition repairs ingredient, the whitening Eradicates wrinkle of respecting delicate flesh.By the compounding of ingredient in formula so that of the invention
Moisturiser is provided simultaneously with moisturizing, anti-blue light, reparation, crease-resistant, whitening spot-removing multi-efficiency.
Specific embodiment
For more concise displaying technical solution of the present invention, objects and advantages, combined with specific embodiments below
The present invention is described in further detail.
The formula of embodiment 1-6 multiple-effect moisturiser, such as table 1:
Embodiment 7
The present embodiment provides a kind of preparation methods of multiple-effect moisturiser, the described method comprises the following steps:
(1) A phase is weighed into emulsion pot, opens homogeneous until substantially uniformity, stirring are after twenty minutes, spare；Wherein A phase raw material
It is poly- including ring five dimethyl silicone polymer, PEG/PPG-20/15 dimethyl silicone polymer, ring five dimethyl silicone polymer, ring five
The poly- first siloxanes of dimethyl siloxane/tristearin oxygen/dimethione copolymer/dimethyl silicone polymer, tocopherol, the Atlantic Ocean
Helmet chest porgy oil, dipalmitoyl hydroxyproline, white pond flower seed oil, pomegranate berry extract, octanoic acid, Triglyceride DDD；
(2) Material in B phase is weighed into water phase, begins to warm up stirring, insulated and stirred 20 minutes；45 DEG C are cooled to, C is added
Phase, D phase, E phase, it is spare after mixing evenly；Wherein B phase raw material include 1,3- propylene glycol, it is Sodium Hyaluronate cross-linked polymer, transparent
Matter acid sodium, acetylation Sodium Hyaluronate, hydrolysis Sodium Hyaluronate, sodium chloride, butanediol, niacinamide, methyl hydroxybenzoate, trehalose,
Anjidew NL50；Wherein C phase raw material includes eryngium maritimum callus tissue culture filtrate, water；Wherein D phase raw material includes butterflybush flower extraction
Object, blueberry berry extract, xanthan gum, citric acid, gluconolactone, calcium gluconate, hylocereus berry extract, leucojum aestivum bulb
Extract, nipa palm seed, extractive of olive growing leaves；Wherein E phase raw material includes Phenoxyethanol, Sensiva SC50, essence；
(3) B phase is slowly pumped into (time control in 30min) under fast stirring, when especially starting revolving speed 2000 with
On, after adding, after stirring 10min, open homogeneous 1~2 minute, it is fixed depending on consistency；
(4) inspection declaration, qualified discharging are to get multiple-effect moisturiser.
Comparative example 1
Comparative example 1 is the similar product of moisturiser of the present invention, including following components by weight percent: 3 parts of emulsifier, mineral oil
2 parts of rouge, 10.05 parts of hydrophily moisturizing chemical agent, 1.5 parts of oil moisture's chemical agent, 5 parts of extract solution from aloe, angelica extract 0.4
Part, 0.5 part of rhodiola extract, 73.93 parts of distilled water.
By embodiment 1-6 and the moisturiser (the wherein preparation method that embodiment 1-6 is all made of embodiment 7) of comparative example 1 into
Row safety and effect assessment, experimental method are as follows:
One, human skin patch spot experiment
Tested crowd's number: 150 people；Age: between 20-50 years old；Health status: skin health of being tried, no skin disease
Allergies meet subject and volunteer inclusion criteria.10 groups are divided into, every group of 15 people.
Patch spot method: selecting qualified spot tester, with closed patch experiment method, by tested material about 0.020g~
For 0.025g drop in spot tester, external application special adhesive tape is covered on subject back, and tested material is removed after 24 hours, after removing respectively
0.5, observation dermoreaction in 6,12,24,48 hours, records its knot according to dermoreaction grade scale in " cosmetics health specification "
Fruit.
Test result:
Human skin patch test result is shown: each group subject passes through the moisturiser patch of the invention of embodiment 1-6
Test, wherein 0 skin adverse reaction occurs, illustrates the moisturizing in observation dermoreaction in 0.5,6,12,24,48 hour
Frost uses safe.
Two, effect detection:
1, moistening effect
It is tested using Multi probe skinanalysis apparatus MPA4, is popped one's head in by moisture measurement, test obtains human skin moisture retention
Test data.Experimental method: taking on the inside of left arm, and equal portions draw point seven regions 2cm*2cm (A, B, C, D, E, F, G, H), takes
0.2g embodiment 1-6,1 sample of comparative example respectively smear a region, and the 7th region is blank, not spread product: smearing real in the area A
Apply example 1；Smear embodiment 2 in the area B；Smear embodiment 3 in the area C；Smear embodiment 4 in the area D；Smear embodiment 5 in the area E；The area F, which is smeared, to implement
Example 6；Smear market similar product (comparative example 1) in the area G；The area H is white space.As a result such as table 2:
Table 2: embodiment 1-5 and comparative example 4 (similar product) moistening effect test result
2, anti-blue light effect
Certain density present example sample is added as a circadian rhythm disrupting agent in blue light and ultraviolet radiation,
It can effectively inhibit to destroy oxidative phenomena caused by (blue light) as circadian rhythm, be answered by reducing the oxidation of ultraviolet radiation inductivity
Free radical caused by swashing acts on to provide skin sparing.Experimental method: each experimental group chooses 10 female volunteers (23-
35 years old, average age 28 years old), it is applied on the face using the embodiment of the present invention and comparative example, daily two since 7 points at night
A hour, volunteers, which are in, to be watched artificial light curtain (tablet computer), is used continuously 1 month, logical using goniospectrophotometer
Cross colorimetric method measurement skin complexion.The equipment can characterize the main aspect of skin: brightness/dimness degree, color and surface appearance.
Test result such as table 3:
Table 3: embodiment 1-6,1 subject of comparative example brightness/dimness degree, skin complexion promotion degree testing result
3, crease-resistant, whitening spot-removing effect
Detection method: embodiment 1-6 and the sample of comparative example 1 front and back are used using the detection of U.S. Visia skin detection instrument
Spot, wrinkle.Detection spot is to be shot using standard white light, refer to visible, skin surface the spot of naked eyes or epidermis its
Its pigementation, wrinkle: skin rule filament is read using Visia skin detection instrument using before sample, is used sample one month
After reuse Visia detection, read skin rule filament.
Experimental method: each experimental group chooses 10 female volunteers (25-55 years old, average age 40 years old), tester
Each sample coating in face, is pressed commentary graduation and scored, added up to the scoring of appraiser's entirety, it is flat to calculate it by everyone
Mean value is determined according to following grade determinating references.It should be noted that assessment item by sample coating in face, examination
It is tried out 2 times with personnel, is evaluated after continuously trying out one month sooner or later daily.As a result such as table 4, table 5
The scoring of grade absolute evaluation:
It is very good: 9-10 points
It is good: 6-8 points
General: 3-5 points poor: 0-3 points
Table 4: spot effect of embodiment 1-6 and comparative example 1 (the competing product in market) scoring
Table 5: anti-wrinkle effect of embodiment 1-6 and comparative example 1 (the competing product in market) scoring
By table 2-5 it is found that embodiment 1-6 and comparative example 1 try effect comparison result it is found that multiple-effect moisturiser energy of the invention
The wettability of long-acting lasting holding skin, subject's spot and wrinkle also have different degrees of improvement relatively commercially available similar
The effect of product will get well (embodiment 1,3,6).Due to lacking hylocereus berry extract, niacinamide in embodiment 2；In embodiment 4
Lack Flos Buddlejae extract, eryngium maritimum callus tissue culture filtrate and 1,3- propylene glycol；Lack in embodiment 5 nipa palm seed/
Ascorbic acid, therefore the moistening effect of embodiment 2,4,5 is good without other embodiments, while not having the function to whitening spot-removing
Can so that the spot of the subject in embodiment 2,4,5 and wrinkle improvement it is unobvious, illustrate moisturiser of the invention moisturizing,
Whitening spot-removing effect be very it will be evident that and embodiment 3 moistening effect it is best.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (10)
1. a kind of multiple-effect moisturiser, which is characterized in that contain the following parts by weight: 0.01-3 parts of Flos Buddlejae extract is got over
0.01-2 parts of tangerine berry extract, 0.01-2 parts of xanthan gum, 0.01-2 parts of citric acid, 0.01-2 parts of gluconolactone, calcium gluconate
0.01-2 parts, 0.01-5 parts of hylocereus berry extract, 0.01-5 parts of Phenoxyethanol, 0.01-5 parts of sodium pyrosulfite, leucojum aestivum
0.01-3 parts of bulb extract, 0.01-3 parts of extractive of olive growing leaves, 0.1-3 parts of niacinamide, 0.01-2 parts of pomegranate berry extract,
0.01-2 parts of dipalmitoyl hydroxyproline, 0.001-0.5 parts of eryngium maritimum callus tissue culture filtrate, nipa palm seed 0.01-3
Part, 0.01-3 parts of ascorbic acid, 0.01-18 parts of skin conditioning agent, 0.2-30 parts of emollient, 0.1-68 parts of moisturizer, preservative
0.01-1.4 parts, 0.05-1 parts of antioxidant, 1-5 parts of emulsifier, 0.2-2 parts of stabilizer, 0.01-0.3 parts of essence.
2. multiple-effect moisturiser as described in claim 1, which is characterized in that contain the following parts by weight: butterflybush flower is extracted
0.1-1.5 parts of object, 0.25-1 parts of blueberry berry extract, 0.25-1 parts of xanthan gum, 0.25-1 parts of citric acid, gluconolactone
0.25-1 parts, 0.25-1 parts of calcium gluconate, 0.5-3 parts of hylocereus berry extract, 0.5-3 parts of Phenoxyethanol, sodium pyrosulfite
0.5-3 parts, 0.1-2 parts of leucojum aestivum bulb extract, 0.1-2 parts of extractive of olive growing leaves, 0.5-2 parts of niacinamide, pomegranate fruit
0.15-1 parts of extract, 0.5-1.8 parts of dipalmitoyl hydroxyproline, eryngium maritimum callus tissue culture filtrate 0.01-1.3
Part, 0.1-2 parts of nipa palm seed, 0.01-3 parts of ascorbic acid, 0.01-18 parts of skin conditioning agent, 0.2-30 parts of emollient, moisturizer
0.1-68 parts, 0.01-1.4 parts of preservative, 0.05-1 parts of antioxidant, 1-5 parts of emulsifier, 0.2-2 parts of stabilizer, essence
0.01-0.3 parts.
3. multiple-effect moisturiser as claimed in claim 1 or 2, which is characterized in that the skin conditioning agent is selected from the poly- diformazan of ring five
Radical siloxane, the poly- first siloxanes of stearic oxygen, dimethione copolymer, dimethyl silicone polymer, Atlantic Ocean helmet chest porgy are oily, saturating
Bright matter acid sodium cross-linked polymer, Sodium Hyaluronate, acetylation Sodium Hyaluronate, hydrolysis one of Sodium Hyaluronate or it is any
Combination.
4. multiple-effect moisturiser as claimed in claim 3, which is characterized in that the skin conditioning agent includes the group of following parts by weight
Point: Atlantic Ocean 0.01-3 parts, 0.1-5 parts ring five dimethyl silicone polymers of helmet chest porgy oil, the poly- first siloxanes of stearic oxygen, poly- diformazan silicon
The mixture of siloxane copolymers and dimethyl silicone polymer, 0.1-10 part Sodium Hyaluronate cross-linked polymer, Sodium Hyaluronate, second
Acylated Sodium Hyaluronate and the mixture for hydrolyzing Sodium Hyaluronate.
5. multiple-effect moisturiser as described in claim 1, which is characterized in that the emollient is selected from five polydimethylsiloxanes of ring
One of alkane, white pond flower seed oil or combinations thereof.
6. multiple-effect moisturiser as claimed in claim 5, which is characterized in that the emollient contains the following parts by weight:
5-25 parts of ring five dimethyl silicone polymer, 0.2-5 parts of white pond flower seed oil.
7. multiple-effect moisturiser as described in claim 1, which is characterized in that the moisturizer be selected from 1,3-PD, butanediol,
One of trehalose, Anjidew NL50 or any combination thereof.
8. multiple-effect moisturiser as claimed in claim 7, which is characterized in that the moisturizer contains the following parts by weight:
2-30 parts of 1,3- propylene glycol, 2-25 parts of butanediol, 0.1-3 parts of trehalose, 0.1-10 parts of Anjidew NL50.
9. multiple-effect moisturiser as described in claim 1, which is characterized in that the preservative be selected from methyl hydroxybenzoate, Phenoxyethanol,
One of Sensiva SC50 or any combination thereof.
10. a kind of preparation method for preparing multiple-effect moisturiser as claimed in claims 1-9, comprising the following steps:
(1) A phase is weighed into emulsion pot, opens homogeneous until substantially uniformity, stirring are after twenty minutes, spare；Wherein A phase raw material includes
Ring five dimethyl silicone polymer, PEG/PPG-20/15 dimethyl silicone polymer, ring five dimethyl silicone polymer, the poly- diformazan of ring five
The poly- first siloxanes of radical siloxane/tristearin oxygen/dimethione copolymer/dimethyl silicone polymer, tocopherol, Atlantic Ocean helmet chest
Porgy oil, dipalmitoyl hydroxyproline, white pond flower seed oil, pomegranate berry extract, octanoic acid, Triglyceride DDD；
(2) Material in B phase is weighed into water phase, begins to warm up stirring, insulated and stirred 20 minutes；45 DEG C are cooled to, C phase, D is added
Phase, E phase, it is spare after mixing evenly；Wherein B phase raw material includes 1,3- propylene glycol, Sodium Hyaluronate cross-linked polymer, hyaluronic acid
Sodium, acetylation Sodium Hyaluronate, hydrolysis Sodium Hyaluronate, sodium chloride, butanediol, niacinamide, methyl hydroxybenzoate, trehalose, PCA
Sodium；Wherein C phase raw material includes eryngium maritimum callus tissue culture filtrate, water；Wherein D phase raw material include Flos Buddlejae extract,
Blueberry berry extract, xanthan gum, citric acid, gluconolactone, calcium gluconate, hylocereus berry extract, leucojum aestivum bulb mention
Take object, nipa palm seed, extractive of olive growing leaves；Wherein E phase raw material includes Phenoxyethanol, Sensiva SC50, essence；
(3) B phase is slowly pumped into (time controls in 30min) under fast stirring, 2000 or more revolving speed, add when especially starting
After complete, after stirring 10min；Open homogeneous 1~2 minute, it is fixed depending on consistency；
(4) inspection declaration, qualified discharging are to get multiple-effect moisturiser.
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