CN1093589A - A kind of medicine for the treatment of acne---acne spirit - Google Patents
A kind of medicine for the treatment of acne---acne spirit Download PDFInfo
- Publication number
- CN1093589A CN1093589A CN 93110955 CN93110955A CN1093589A CN 1093589 A CN1093589 A CN 1093589A CN 93110955 CN93110955 CN 93110955 CN 93110955 A CN93110955 A CN 93110955A CN 1093589 A CN1093589 A CN 1093589A
- Authority
- CN
- China
- Prior art keywords
- acne
- vitamin
- treatment
- medicine
- spirit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 206010000496 acne Diseases 0.000 title claims abstract description 14
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 12
- 239000003814 drug Substances 0.000 title claims abstract description 12
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 8
- 229930003270 Vitamin B Natural products 0.000 claims abstract description 8
- 235000019156 vitamin B Nutrition 0.000 claims abstract description 8
- 239000011720 vitamin B Substances 0.000 claims abstract description 8
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 4
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 4
- 239000011718 vitamin C Substances 0.000 claims abstract description 4
- 239000002552 dosage form Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 2
- 229940040145 liniment Drugs 0.000 claims description 2
- 239000000865 liniment Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- SHGAZHPCJJPHSC-UHFFFAOYSA-N Panrexin Chemical compound OC(=O)C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-UHFFFAOYSA-N 0.000 claims 2
- SHGAZHPCJJPHSC-NUEINMDLSA-N Isotretinoin Chemical compound OC(=O)C=C(C)/C=C/C=C(C)C=CC1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-NUEINMDLSA-N 0.000 claims 1
- 241000882890 Renova Species 0.000 claims 1
- 238000007796 conventional method Methods 0.000 claims 1
- 229960005280 isotretinoin Drugs 0.000 claims 1
- 229940059527 renova Drugs 0.000 claims 1
- 229940002683 retin-a Drugs 0.000 claims 1
- RBCOYOYDYNXAFA-UHFFFAOYSA-L (5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate Chemical compound CC1=NC=C(COP([O-])([O-])=O)C(C)=C1O RBCOYOYDYNXAFA-UHFFFAOYSA-L 0.000 abstract 1
- 239000012567 medical material Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 206010000050 Abdominal adhesions Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- 241001303601 Rosacea Species 0.000 description 1
- 244000173853 Sanguisorba officinalis Species 0.000 description 1
- 235000008282 Sanguisorba officinalis Nutrition 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000002650 habitual effect Effects 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 201000004700 rosacea Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 210000003859 smegma Anatomy 0.000 description 1
- 239000007779 soft material Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 201000005060 thrombophlebitis Diseases 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of specific medicament for the treatment of acne, it contains Radix Sanguisorbae, vitamin C, vitamin B
1And/or vitamin B
6
Description
The invention belongs to a kind of Chinese medicine preparation, it is to be primary raw material with the Chinese medicine Radix Sanguisorbae, makes the specific medicament of treatment acne.
In the prior art, the application for a patent for invention CN1051506A that is submitted on October 8th, 90 by the applicant discloses a kind of preparation method of new type sanguisorba pharmaceutical, in this application, with the Radix Sanguisorbae is that primary raw material is prepared into different dosage forms, can be used for treatment seat skin ulcer, rosacea, thrombophlebitis, intestinal adhesion, chronic non-specific ulcerative colitis, leukopenia, immunodeficiency disease and has antibiotic potentiation.Acne vulgaris is common in youth of both sexes, how to take place in adolescence, good sending out in face, neck, breast and back portion, and clinical manifestation is an erythra, sees with acne, hair follicle inflammatory pimple, papulovesicle, pimple and lesser tubercle more.The applicant is at the clinical manifestation of unusual acne, and clinical observation and practice through in a few years on the basis of above-mentioned preparation, improve prescription, and the treatment effective percentage of acne vulgaris is increased substantially.
Therefore, the object of the invention is based on my clinical practice, and a kind of specific medicament for the treatment of acne is provided.
Prescription of the present invention is
Radix Sanguisorbae 0.3-0.5g vitamin C 300-500mg vitamin B
1And/or vitamin B
640-50mg
According to habitual formulation method, the dosage form that above-mentioned formulation can be become the various patients of being suitable for to use, preferably exterior-applied formulation.
Prescription of the present invention technology routinely is prepared into tablet, pill, electuary, powder, capsule or oral liquid, can also be prepared into external-use lotion or liniment.
When being made dosage form, above-mentioned prescription can add excipient.
Medicine of the present invention has good antibacterial action, and nonspecific inflammation is also had certain curative effect.Can killing microorganisms and the treatment nonspecific inflammation, can improve metabolism again and make smegma and drain multiple health, and promote wound healing, thereby reach the purpose of treatment.Use medicine of the present invention to observe 48 examples altogether, total effective rate is 100%.
Embodiment:
Radix Sangusorbae is chosen decontamination, wash, thinly slice, dry, as raw medicinal material.Get the medical material of crude drug full dose 1/3rd, in the steriliser of packing into, carried out moist heat sterilization 30 minutes at 110 ℃, be dried and crushed into fine powder, it is standby to cross 100 mesh sieves.The medical material of crude drug residue 2/3rds amounts is decocted with water three times, respectively boiled 1.5 hours with the second time for the first time, amount of water is 6.5 times of medical material amount, boils for the third time 1 hour, and amount of water is 4 times of medical material amount.With medical filtration, merging filtrate is concentrated into the thick paste of relative density (60 ℃) more than 1.15, and receiving the cream amount is 1/2nd of decoction amount.Get crude drug powder 5000 grams, thick paste 5000 grams, vitaminize C 10000g, vitamin B
11000g is mixed and made into soft material, granulates tabletting, every heavy 0.3 gram, bottling packing.
Claims (3)
1, a kind of medicine for the treatment of acne is characterized in that it contains Radix Sanguisorbae 0.3-0.5g, vitamin C 300-500mg, vitamin B
1And/or vitamin B
640-50mg.
2, a kind of preparation method of Retinoids, Retin-A, Renova, Accutane is characterized in that Radix Sanguisorbae 0.3-0.5g, vitamin C 300-500mg, vitamin B
1With/vitamin B
640-50mg makes pharmaceutically acceptable dosage form according to a conventional method.
3, according to the said method of claim 2, wherein pharmaceutically acceptable dosage form comprises tablet, pill, electuary, powder, capsule, oral liquid, externally applied liniment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93110955A CN1052156C (en) | 1993-04-14 | 1993-04-14 | Medicine for curing acne-"Fenciling" |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93110955A CN1052156C (en) | 1993-04-14 | 1993-04-14 | Medicine for curing acne-"Fenciling" |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1093589A true CN1093589A (en) | 1994-10-19 |
| CN1052156C CN1052156C (en) | 2000-05-10 |
Family
ID=4988767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93110955A Expired - Lifetime CN1052156C (en) | 1993-04-14 | 1993-04-14 | Medicine for curing acne-"Fenciling" |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1052156C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103372076A (en) * | 2012-04-20 | 2013-10-30 | 北京北大维信生物科技有限公司 | Medicine for treating diseases caused by propionibacterium acnes and application of sanguisorba officinalis and/or sanguisorba officinalis extract |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1016141B (en) * | 1990-10-08 | 1992-04-08 | 刘墨森 | Preparation method of novel sanguisorba officinalis preparation |
-
1993
- 1993-04-14 CN CN93110955A patent/CN1052156C/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103372076A (en) * | 2012-04-20 | 2013-10-30 | 北京北大维信生物科技有限公司 | Medicine for treating diseases caused by propionibacterium acnes and application of sanguisorba officinalis and/or sanguisorba officinalis extract |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1052156C (en) | 2000-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |