CN109287633A - A kind of microbicide compositions - Google Patents
A kind of microbicide compositions Download PDFInfo
- Publication number
- CN109287633A CN109287633A CN201811233346.0A CN201811233346A CN109287633A CN 109287633 A CN109287633 A CN 109287633A CN 201811233346 A CN201811233346 A CN 201811233346A CN 109287633 A CN109287633 A CN 109287633A
- Authority
- CN
- China
- Prior art keywords
- composition
- ethyl ethylthio
- ethylthio sulfonate
- toverticilliumdahliaactivitie activitie
- activator protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 65
- 230000003641 microbiacidal effect Effects 0.000 title claims abstract description 15
- 229940124561 microbicide Drugs 0.000 title claims abstract description 15
- 239000002855 microbicide agent Substances 0.000 title claims abstract description 15
- 230000000694 effects Effects 0.000 claims abstract description 64
- OICGFSUWXCJLCO-UHFFFAOYSA-N 1-ethylsulfonylsulfanylethane Chemical compound CCSS(=O)(=O)CC OICGFSUWXCJLCO-UHFFFAOYSA-N 0.000 claims abstract description 54
- 108091006088 activator proteins Proteins 0.000 claims abstract description 46
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 35
- 239000002552 dosage form Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 9
- 239000004530 micro-emulsion Substances 0.000 claims description 8
- 239000000575 pesticide Substances 0.000 claims description 8
- 239000004563 wettable powder Substances 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 239000003921 oil Substances 0.000 claims description 7
- 239000002904 solvent Substances 0.000 claims description 7
- 239000000853 adhesive Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 5
- 239000012752 auxiliary agent Substances 0.000 claims description 5
- 239000002917 insecticide Substances 0.000 claims description 5
- 239000004094 surface-active agent Substances 0.000 claims description 5
- 208000031968 Cadaver Diseases 0.000 claims description 4
- 239000002270 dispersing agent Substances 0.000 claims description 3
- 239000002562 thickening agent Substances 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- 239000000470 constituent Substances 0.000 claims description 2
- 239000003337 fertilizer Substances 0.000 claims description 2
- 230000004913 activation Effects 0.000 claims 1
- 230000000855 fungicidal effect Effects 0.000 abstract description 6
- 238000012360 testing method Methods 0.000 abstract description 6
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 5
- 238000013329 compounding Methods 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 4
- 239000000417 fungicide Substances 0.000 abstract description 4
- 238000002360 preparation method Methods 0.000 abstract description 4
- 238000001228 spectrum Methods 0.000 abstract description 4
- 208000031888 Mycoses Diseases 0.000 abstract description 2
- 230000009471 action Effects 0.000 abstract description 2
- 230000007246 mechanism Effects 0.000 abstract description 2
- 201000010099 disease Diseases 0.000 description 30
- -1 carrier Substances 0.000 description 16
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 14
- 241000196324 Embryophyta Species 0.000 description 13
- 206010039509 Scab Diseases 0.000 description 11
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 10
- 240000003768 Solanum lycopersicum Species 0.000 description 10
- 241000209140 Triticum Species 0.000 description 9
- 235000021307 Triticum Nutrition 0.000 description 9
- 240000008067 Cucumis sativus Species 0.000 description 8
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 8
- 230000001580 bacterial effect Effects 0.000 description 8
- 230000003902 lesion Effects 0.000 description 8
- 239000003814 drug Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 230000001988 toxicity Effects 0.000 description 7
- 231100000419 toxicity Toxicity 0.000 description 7
- 240000007594 Oryza sativa Species 0.000 description 6
- 235000007164 Oryza sativa Nutrition 0.000 description 6
- 235000019198 oils Nutrition 0.000 description 6
- 235000009566 rice Nutrition 0.000 description 6
- 230000002195 synergetic effect Effects 0.000 description 6
- 241000221785 Erysiphales Species 0.000 description 5
- 240000008042 Zea mays Species 0.000 description 5
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 238000012545 processing Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- HIXDQWDOVZUNNA-UHFFFAOYSA-N 2-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxychromen-4-one Chemical compound C=1C(OC)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=C(OC)C(OC)=C1 HIXDQWDOVZUNNA-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 235000011430 Malus pumila Nutrition 0.000 description 4
- 235000015103 Malus silvestris Nutrition 0.000 description 4
- 206010064458 Penicilliosis Diseases 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 4
- 239000007859 condensation product Substances 0.000 description 4
- 229920000151 polyglycol Polymers 0.000 description 4
- 239000010695 polyglycol Substances 0.000 description 4
- 230000002265 prevention Effects 0.000 description 4
- 230000003449 preventive effect Effects 0.000 description 4
- 239000002689 soil Substances 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- 241000207199 Citrus Species 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 244000299507 Gossypium hirsutum Species 0.000 description 3
- 101000668058 Infectious salmon anemia virus (isolate Atlantic salmon/Norway/810/9/99) RNA-directed RNA polymerase catalytic subunit Proteins 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- 241000233679 Peronosporaceae Species 0.000 description 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 3
- 235000009754 Vitis X bourquina Nutrition 0.000 description 3
- 235000012333 Vitis X labruscana Nutrition 0.000 description 3
- 240000006365 Vitis vinifera Species 0.000 description 3
- 235000014787 Vitis vinifera Nutrition 0.000 description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 3
- 239000000440 bentonite Substances 0.000 description 3
- 229910000278 bentonite Inorganic materials 0.000 description 3
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 3
- 235000020971 citrus fruits Nutrition 0.000 description 3
- 235000005822 corn Nutrition 0.000 description 3
- 235000019441 ethanol Nutrition 0.000 description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 3
- 230000010534 mechanism of action Effects 0.000 description 3
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical class C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 230000001717 pathogenic effect Effects 0.000 description 3
- NFAOATPOYUWEHM-UHFFFAOYSA-N 2-(6-methylheptyl)phenol Chemical class CC(C)CCCCCC1=CC=CC=C1O NFAOATPOYUWEHM-UHFFFAOYSA-N 0.000 description 2
- 239000005995 Aluminium silicate Substances 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 244000241235 Citrullus lanatus Species 0.000 description 2
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- IGFHQQFPSIBGKE-UHFFFAOYSA-N Nonylphenol Natural products CCCCCCCCCC1=CC=C(O)C=C1 IGFHQQFPSIBGKE-UHFFFAOYSA-N 0.000 description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 241000082085 Verticillium <Phyllachorales> Species 0.000 description 2
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000000274 adsorptive effect Effects 0.000 description 2
- 125000002877 alkyl aryl group Chemical group 0.000 description 2
- XXROGKLTLUQVRX-UHFFFAOYSA-N allyl alcohol Chemical compound OCC=C XXROGKLTLUQVRX-UHFFFAOYSA-N 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 2
- DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 125000004836 hexamethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[*:1] 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 229920005610 lignin Polymers 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 235000009973 maize Nutrition 0.000 description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N monobenzene Natural products C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- 150000002790 naphthalenes Chemical class 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000012424 soybean oil Nutrition 0.000 description 2
- 239000003549 soybean oil Substances 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- 239000008158 vegetable oil Substances 0.000 description 2
- 238000012795 verification Methods 0.000 description 2
- WHOZNOZYMBRCBL-OUKQBFOZSA-N (2E)-2-Tetradecenal Chemical compound CCCCCCCCCCC\C=C\C=O WHOZNOZYMBRCBL-OUKQBFOZSA-N 0.000 description 1
- NWACCXJCJNDIDK-UHFFFAOYSA-N 1,2,3-tributylbenzene Chemical compound CCCCC1=CC=CC(CCCC)=C1CCCC NWACCXJCJNDIDK-UHFFFAOYSA-N 0.000 description 1
- DUIOKRXOKLLURE-UHFFFAOYSA-N 2-octylphenol Chemical compound CCCCCCCCC1=CC=CC=C1O DUIOKRXOKLLURE-UHFFFAOYSA-N 0.000 description 1
- 241000223602 Alternaria alternata Species 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 241001530056 Athelia rolfsii Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 241000228438 Bipolaris maydis Species 0.000 description 1
- 240000007124 Brassica oleracea Species 0.000 description 1
- 235000003899 Brassica oleracea var acephala Nutrition 0.000 description 1
- 235000011301 Brassica oleracea var capitata Nutrition 0.000 description 1
- 235000001169 Brassica oleracea var oleracea Nutrition 0.000 description 1
- 229910021532 Calcite Inorganic materials 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241001123534 Colletotrichum coccodes Species 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- 241000510928 Erysiphe necator Species 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 244000307700 Fragaria vesca Species 0.000 description 1
- 235000016623 Fragaria vesca Nutrition 0.000 description 1
- 235000011363 Fragaria x ananassa Nutrition 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241000241602 Gossypianthus Species 0.000 description 1
- 241001272567 Hominoidea Species 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 235000017858 Laurus nobilis Nutrition 0.000 description 1
- 229920001732 Lignosulfonate Polymers 0.000 description 1
- 241000220225 Malus Species 0.000 description 1
- 235000009811 Momordica charantia Nutrition 0.000 description 1
- 235000009812 Momordica cochinchinensis Nutrition 0.000 description 1
- 240000001740 Momordica dioica Species 0.000 description 1
- 235000018365 Momordica dioica Nutrition 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004721 Polyphenylene oxide Substances 0.000 description 1
- 101710202013 Protein 1.5 Proteins 0.000 description 1
- 240000001987 Pyrus communis Species 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 1
- 235000003434 Sesamum indicum Nutrition 0.000 description 1
- 244000040738 Sesamum orientale Species 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical compound OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 description 1
- 244000125380 Terminalia tomentosa Species 0.000 description 1
- 235000005212 Terminalia tomentosa Nutrition 0.000 description 1
- YPWFISCTZQNZAU-UHFFFAOYSA-N Thiane Chemical compound C1CCSCC1 YPWFISCTZQNZAU-UHFFFAOYSA-N 0.000 description 1
- 102100022972 Transcription factor AP-2-alpha Human genes 0.000 description 1
- 101710189834 Transcription factor AP-2-alpha Proteins 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 150000001447 alkali salts Chemical class 0.000 description 1
- 150000008055 alkyl aryl sulfonates Chemical class 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 150000008052 alkyl sulfonates Chemical class 0.000 description 1
- OBETXYAYXDNJHR-UHFFFAOYSA-N alpha-ethylcaproic acid Natural products CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 208000020282 anthrax disease Diseases 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 229960000892 attapulgite Drugs 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 150000001555 benzenes Chemical class 0.000 description 1
- 239000001390 capsicum minimum Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- OANSOJSBHVENEI-UHFFFAOYSA-N cyclohexene-1-carbaldehyde Chemical compound O=CC1=CCCCC1 OANSOJSBHVENEI-UHFFFAOYSA-N 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- GUJOJGAPFQRJSV-UHFFFAOYSA-N dialuminum;dioxosilane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[O-2].[Al+3].[Al+3].O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O GUJOJGAPFQRJSV-UHFFFAOYSA-N 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N dimethyl sulfoxide Natural products CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 239000010459 dolomite Substances 0.000 description 1
- 229910000514 dolomite Inorganic materials 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000007046 ethoxylation reaction Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000009313 farming Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 230000035784 germination Effects 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 229910052622 kaolinite Inorganic materials 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000002015 leaf growth Effects 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 239000012764 mineral filler Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910052901 montmorillonite Inorganic materials 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 244000039328 opportunistic pathogen Species 0.000 description 1
- 229910052625 palygorskite Inorganic materials 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 229940044652 phenolsulfonate Drugs 0.000 description 1
- 229940044654 phenolsulfonic acid Drugs 0.000 description 1
- LGRFSURHDFAFJT-UHFFFAOYSA-N phthalic anhydride Chemical compound C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000004576 sand Substances 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- HFQQZARZPUDIFP-UHFFFAOYSA-M sodium;2-dodecylbenzenesulfonate Chemical compound [Na+].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O HFQQZARZPUDIFP-UHFFFAOYSA-M 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000009331 sowing Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 125000004646 sulfenyl group Chemical group S(*)* 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 108010033370 transcription factor AP-5 Proteins 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000004562 water dispersible granule Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/08—Sulfonic acid halides; alpha-Hydroxy-sulfonic acids; Amino-sulfonic acids; Thiosulfonic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/30—Microbial fungi; Substances produced thereby or obtained therefrom
Landscapes
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Virology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides a kind of microbicide compositions, the composition includes two kinds of effective component toVerticilliumdahliaActivitie Activitie S of Relative activator proteins and S-Ethyl ethylthio sulfonate, and the weight ratio between two components is 1:1~80.The present invention also provides the Preparation method and uses of the composition.Test result shows that above-mentioned bactericidal composition synergy provided by the invention is obvious, it is often more important that amount of application is reduced, and use cost reduces.The bactericidal composition can effectively prevent certain specific bacteriums or the fungal disease of crop.By compounding the fungicide of different role mechanism and the mode of action, there is good effect for expand fungicidal spectrum and delay germ resistance and improve control efficiency etc..
Description
Technical field
The invention belongs to agriculture plant protection field, more particularly to a kind of with the microbicide compositions for improving performance,
Concretely relate to a kind of microbicide compositions comprising toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate.
Background technique
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein is a kind of novel protein screen, separate from Alternariaspp, being purified into, main logical
Molecular immune system in activated plant body is crossed, plant autoimmunity is improved；It is adjusted by a series of intracorporal metabolism of excitation plant
Control promotes plant roots, stem, leaf growth and improves chlorophyll content, improve crop yield, has to plurality of plant diseases higher anti-
Effect
S-Ethyl ethylthio sulfonate (Ethylicin) element is a kind of plant bionic pesticide, and Effictive nuisancelless wide spectrum bionic fungicide has both plant
The effect of object growth regulating can promote rudiment, improve germination percentage, increase yield and improving quality, be the head of composite bactericide pesticide
Select raw material.Its mechanism of action and thallus include the material effect of sulfenyl, to inhibit the eubolism of thallus.S-Ethyl ethylthio sulfonate can be effective
Inhibit cotton seedling blight, wilt disease, verticillium wilt；Rice blast, bacterial leaf-blight, bakanae disease, seedling rot, banded sclerotial blight；Corn is big
Helminthosporium maydis, yellow leaf, wheat scab, stripe disease, bunt, the slow blight of watermelon, watermelon sprout term disease, cucumber at seedling stage silk floss epidemic disease
Disease, wilt disease, gray mold, scab, downy mildew, soft rot of cabbage, bacterial wilt of ginger, graw mold of tomato, bacterial wilt, capsicum epidemic disease and
Strawberry, Rhizoma Atractylodis Macrocephalae, ginseng, banana, apple, grape, pear tree, tealeaves, horseshoe, flowers, peanut, soybean are more on the crops such as sesame
Kind disease, significant effect.
Actual pesticide experience have shown that, repeat and single-minded apply a kind of reactive compound to prevent and treat disinfect pathogen very
It will lead to the fast selective of germ bacterial strain in more situations, it is usual at present for the risk for reducing resistance germ bacterial strain selectivity
Disinfect pathogen is prevented and treated using the mixture of different activities compound.By will have the reactive compound of different role mechanism into
Row combination, can delaying drug resistance generate, reduce amount of application, reduce control cost.
Summary of the invention
The purpose of the present invention is being directed to fungicide resistance and pedo relict problem in practical applications, filters out difference and kill
The fungicide of bacterium principle is compounded, and a kind of new microbicide compositions is obtained, to improve bactericidal agent for preventing and treating effect, delaying drug resistance
It generates, reduces amount of application, reduce control cost.
It is a further object to provide kill comprising two kinds of effective component toVerticilliumdahliaActivitie Activitie S of Relative activator proteins and S-Ethyl ethylthio sulfonate
The preparation method of bacteria composition and the application in agriculture field prevention and treatment corps diseases.
The purpose of the present invention can be achieved by the following measures:
A kind of microbicide compositions, the composition include two kinds of active components of toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate.
Inventor is found by experiment that composition of the invention is increased for preventing and treating crops bacterium or fungal disease
Effect is obvious, it is often more important that amount of application is reduced, and reduces use cost.Chemical combination containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate
Object structure type is different, and mechanism of action is different, and the two compounding can expand fungicidal spectrum, and can delay disease to a certain extent
The generation of opportunistic pathogen resistance and development speed, and no interactions resistance between toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate.
In a preferred embodiment, the weight ratio of active component toVerticilliumdahliaActivitie Activitie S of Relative activator protein and active component S-Ethyl ethylthio sulfonate is
1:1~80 can be more preferably 1:10~70 to make function and effect become apparent from the two weight ratio.
In a kind of preferred scheme, the weight ratio between two component of toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate can be any
Ground is adjusted 1:1,1:2,1:3,1:4,1:5,1:6,1:7,1:8,1:9,1:10,1:11,1 in the range of following proportions:
12、1:13、1:14、1:15、1:16、1:17、1:18、1:19、1:20、1:21、1:22、1:23、1:24、1:25、1:26、1:
27、1:28、1:29、1:30、1:31、1:32、1:33、1:34、1:35、1:36、1:37、1:38、1:39、1:40、1:41、1:
42、1:43、1:44、1:45、1:46、1:47、1:48、1:49、1:50、1:51、1:52、1:53、1:54、1:55、1:56、1:
57、1:58、1:59、1:60、1:61、1:62、1:63、1:64、1:65、1:66、1:67、1:68、1:69、1:70、1:71、1:
72,1:73,1:74,1:75,1:76,1:77,1:78,1:79,1:80 can also match composed model at any of the above two
Enclose it is interior selected, these ratios can be understood as weight ratio, also may include molar ratio.
The dosage form allowed on pesticide can be made by active constituent and insecticides adjuvant or auxiliary material in composition of the invention.Into one
Step, the composition forms agriculture by the active component of 1~85% parts by weight and the insecticides adjuvant of 99~15% parts by weight or auxiliary material
The dosage form allowed on medicine.
The present invention provides the bactericidal compositions comprising toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate to prevent and treat in agriculture field
Purposes in terms of corps diseases, the especially purposes in terms of the fungi or bacterial disease for preventing and treating certain crops.
Above-mentioned composition specifically may include insecticides adjuvant or auxiliary material, such as carrier, solvent, dispersing agent, wetting agent, gluing
One or more of agent, thickener, adhesive, surfactant or fertilizer etc..It can be mixed during application common
Auxiliary agent.
Suitable auxiliary agent or auxiliary material can be solid or liquid, they are usually common substance during formulation,
Such as natural or regenerated minerals, solvent, dispersing agent, wetting agent, adhesive, thickener, adhesive.
The method of administration of the present composition includes the aerial part that composition of the invention is used for plant growth, especially
It is leaf portion or blade face.It can choose seed soaking or be applied to controlling object surface.The frequency and amount of application of application depend on pathogen
Biology and weather life condition.The growth place of plant, such as rice field can be soaked with the liquid preparation of composition, or
Composition is applied in soil by person in solid form, and such as in granular form (soil application), composition can be by soil through planting
Object root enters in plant (systemic action).
Composition of the invention can be prepared into various dosage forms pesticide-acceptable, including but not limited to missible oil, suspension
Agent, wettable powder, water dispersible granules, pulvis, granula, aqua, aqueous emulsion, microemulsion, encapsulated form, mother liquor, female powder etc.,
In a kind of preferred embodiment, dosage form of the invention uses microemulsion, missible oil, wettable powder.According to the property of these compositions with
And application composition purpose to be achieved and ambient conditions, can choose composition to be sprayed, atomizing, dust, broadcast sowing or
Sprinkle the method application poured or the like.
Composition of the invention can be prepared into various dosage forms by known method, can by effective component with help
Agent can uniformly mix together with surfactant when needing, grind, be prepared into required agent such as solvent, solid carrier
Type.
Above-mentioned solvent can be selected from aromatic hydrocarbon, preferably contain 8-12 carbon atom, such as xylene mixture or substituted benzene, phthalein
Esters of gallic acid, such as two octanoic acid of Dibutyl phthalate or phthalandione, fat hydrocarbon, such as thiacyclohexane or paraffin, the ether of pure and mild ethylene glycol and they
And ester, such as ethyl alcohol, ethylene glycol, ethylene glycol monomethyl；Ketone, such as cyclohexanone, highly polar solvent, such as N- methyl -2- pyrrolidines
Ketone, dimethyl sulfoxide or dimethylformamide and vegetable oil or vegetable oil, such as soybean oil.
Above-mentioned solid carrier, such as usually natural mineral fillers, such as talcum, kaolinite for pulvis and dispersible agent
Soil, montmorillonite or atlapulgite.In order to manage the physical property of composition, polymolecularity silicic acid or polymolecularity can also be added
Adsorpting polymerization object carrier, such as granulated adsorptive carriers or non-adsorbed carrier, suitable granulated adsorptive carriers are porous types, it is such as floating
Stone, bentonite or bentonite；Suitable non-adsorbed carrier such as calcite or sand.Further, it is possible to use a large amount of inorganic in nature or having
The prefabricated material to granulate of machine property is as carrier, especially dolomite.
The chemical property of effective component in composition according to the present invention, suitable surfactant are sulfomethylated lignin
Acid, naphthalene sulfonic acids, phenolsulfonic acid, alkali salt or amine salt, alkylaryl sulfonates, alkyl sulfate, alkylsulfonate, fat
Alcohol sulfate, fatty acid and sulphated fatty alcohol glycol ether, there are also the condensation product of sulfonated naphthalene and naphthalene derivatives and formaldehyde, naphthalene or
The condensation product of naphthalene sulfonic acids and phenol and formaldehyde, NONIN HS 240, ethoxylated isooctyl-phenol, octyl phenol, nonyl phenol,
Alkylaryl polyglycol ether, tributyl benzene polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol,
Ethoxylated castor oil, polyoxyethylene alkyl ether, ethylene oxide condensation product, ethoxylation polyoxypropylene, laurel acid polyethylene glycol
Ether acetal, sorbitol ester, lignin sulfite waste liquor and methylcellulose.
Two kinds of effective components show as synergistic effect in composition of the invention, and the activity of the composition is than using individualized
The independent activity of the expected summation of activity and single compound of closing object is more significant.Synergistic effect shows as allowing amount of application
Reduction, broader antifungal control spectrum, quick, more longlasting control efficiency, by a small number of applying only once or several times more
Good control plant pest fungi and broaden the possible administration interval time.These characteristics are plant epiphyte control practices
It especially needs in the process.
In terms of microbicide compositions of the invention can be applied to agriculture field prevention and treatment corps diseases, farming referred herein
Object disease especially uncinula necator, powdery mildew of cucumber, cucumber downy mildew, balsam pear powdery mildew, graw mold of tomato, wheat white powder
Disease, rice blast.But composition of the invention is other than it can prevent and treat aforementioned disease, moreover it is possible to the specific illness of prevention and treatment include but
It is not limited to wheat diseases (such as: wheat scab, wheat powdery mildew, wheat rust), rice disease (such as: rice sheath blight disease, water
Rice false smut, paddy bacterial streak etc.), maize diseases (such as: smut of maize, the leaf blight of corn, corn southern leaf blight), cucumber
Disease (such as: powdery mildew of cucumber, cucumber anthracnose, gray mold of cucumber, cucumber bacterial angular leaf spot), tomato disease are (such as: tomato
Powdery mildew, anthracnose of tomato, tomato virus disease, tomato bacterial angular leaf spot etc.), grape disease (such as: downy mildew of garpe, grape
Gray mold), apple disease (such as: ring rot of apple, apple anthracnose), citrus disease (such as: citrus scab simultaneously, citrus anthrax
Disease), tobacco diseases (such as: wildfire, Alternaria alternate), rape disease (such as: sclerotinia sclerotiorum), cotton disease (such as: cotton
Flower verticillium wilt, cotton wilt) etc..
Other features that bactericidal composition of the invention is shown are main are as follows: 1, composition mixture of the invention have it is obvious
Synergistic effect；2, since two single dose chemical structures of this composition are widely different, the mechanism of action is entirely different, and there is no hand over
Mutual resistance can delay two single doses that generated resistance problem is used alone；3, composition of the invention is to crop safety, preventive effect
It is good.Tests prove that microbicide compositions chemical property of the present invention is stablized, synergy is significant, shows significantly to controlling object
Synergy and complementation.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that described herein, specific examples are only used to explain the present invention, is not used to limit
The fixed present invention, any modifications, equivalent replacements and improvementsmade within the spirit and principles of the invention, etc. should be included in
Within protection scope of the present invention.
Percentage is weight percentage in all formulas of following embodiment.The processing work of the various preparations of the present composition
Skill is the prior art, can be varied according to different situations.
One, dosage form prepares embodiment
(1) processing and embodiment of missible oil
By toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate, mixed with each components such as surfactant and solvents in the ratio of formula
Conjunction is uniformly got product.
Embodiment 1:22% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate missible oil
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 2%, S-Ethyl ethylthio sulfonate 20%, allyl alcohol ether sulfate 6%, lauric acid polyglycol ether
Acetal 5%, soybean oil complements to 100%.
Embodiment 2:36.6% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate missible oil
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.6%, S-Ethyl ethylthio sulfonate 36%, ethoxylated isooctyl-phenol 8%, phenolsulfonate
10%, hexamethylene complements to 100%.
Embodiment 3:81% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate missible oil
ToVerticilliumdahliaActivitie Activitie S of Relative Activating protein-1 %, S-Ethyl ethylthio sulfonate 80%, APES formaldehyde condensation products sulfat 8%,
Aliphatic ester complements to 100%.
(2) processing and embodiment of wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein and the various auxiliary agents of S-Ethyl ethylthio sulfonate and filler etc. are sufficiently mixed in proportion, through ultra-fine grinding
Wettable powder is made after crushing in machine.
Embodiment 4:31.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative Activating protein-1 .5%, S-Ethyl ethylthio sulfonate 30%, bentonite 3%, lauryl sodium sulfate 6%, naphthalene sulfonic acids
Salt 4%, attapulgite complements to 100%.
Embodiment 5:15.5% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.5%, S-Ethyl ethylthio sulfonate 15%, sodium bicarbonate 2%, polymerization of carboxylic acid sodium salt 8%, nonyl phenol
Polyoxyethylene 6%, kaolin complements to 100%.
Embodiment 6:61.2% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate wettable powder
ToVerticilliumdahliaActivitie Activitie S of Relative Activating protein-1 .2%, S-Ethyl ethylthio sulfonate 60%, ammonium sulfate 4%, lignosulfonates 6%, dodecyl
Benzene sulfonic acid sodium salt 6%, kaolin complements to 100%.
(3) processing and embodiment of microemulsion
Active component toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate are dissolved in solvent, then are proportionally added into auxiliary agent and water, is mixed
It closes and uniformly can be prepared by microemulsion.
Embodiment 7:10% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate microemulsion
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 5%, S-Ethyl ethylthio sulfonate 5%, naphthalenesulfonic acid-formaldehyde condensate 8%, ethylene glycol 6%, acetone
10%, water complements to 100%.
Embodiment 8:49.2% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate microemulsion
ToVerticilliumdahliaActivitie Activitie S of Relative Activating protein-1 .2%, S-Ethyl ethylthio sulfonate 48%, alkyl naphthalene formaldehyde condensate sulfonate 10%, ethylene glycol
8%, hexamethylene 16%, water complements to 100%.
Embodiment 9:28.4% toVerticilliumdahliaActivitie Activitie S of Relative activator protein S-Ethyl ethylthio sulfonate microemulsion
ToVerticilliumdahliaActivitie Activitie S of Relative activator protein 0.4%, S-Ethyl ethylthio sulfonate 28%, naphthalenesulfonic acid-formaldehyde condensate 6%, alkyl phenol polyoxy second
Cyclohexene carboxaldehyde condensate sulfate 6%, glycerine 10%, chloroform 12%, water complements to 100%.
Two, drug effect verification test
(1) Assays Example
The incidence that whole strain blade is investigated according to test grade scale, calculates disease index and control efficiency.
Control efficiency is converted into probability value (y), liquor strength (μ g/ml) is converted into logarithm (x), with least square method
Concentration EC50 in calculating virulence equation and inhibiting, the toxicity index and co-toxicity coefficient (CTC) of medicament are calculated according to Sun Yunpei's Method.
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50) * 100
Percentage composition+B medicament toxicity index * the mixture of A in theoretical toxicity index (TTI)=A medicament toxicity index * mixture
The percentage composition of middle B
Co-toxicity coefficient (CTC)=[mixture surveys toxicity index (ATI)/mixtures theoretical toxicity index (TTI)] * 100
CTC≤80, composition show as antagonism, 80 < CTC < 120, and composition shows as summation action, and CTC >=
120, composition shows as synergistic effect.
1, toVerticilliumdahliaActivitie Activitie S of Relative activator protein is compounded with S-Ethyl ethylthio sulfonate tests tomato penicilliosis toxicity test
1. toVerticilliumdahliaActivitie Activitie S of Relative activator protein of table is compounded with S-Ethyl ethylthio sulfonate to tomato penicilliosis toxicity test interpretation of result
| Medicament title | EC50(ug/mL) | ATI | TTI | CTC |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein | 7.87 | 100.00 | \ | \ |
| S-Ethyl ethylthio sulfonate | 10.16 | 77.46 | \ | \ |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=10:1 | 6.66 | 118.12 | 97.95 | 120.59 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:1 | 6.33 | 124.28 | 88.73 | 140.06 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:10 | 6.48 | 121.43 | 79.51 | 152.73 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:20 | 6.21 | 126.74 | 78.53 | 161.39 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:30 | 5.81 | 135.47 | 78.19 | 173.26 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:40 | 5.48 | 143.68 | 78.01 | 184.18 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:50 | 5.86 | 134.39 | 77.90 | 172.51 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:60 | 6.29 | 125.18 | 77.83 | 160.84 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:70 | 6.70 | 117.51 | 77.78 | 151.09 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:80 | 7.25 | 108.53 | 77.74 | 139.61 |
| ToVerticilliumdahliaActivitie Activitie S of Relative activator protein: S-Ethyl ethylthio sulfonate=1:90 | 8.55 | 92.06 | 77.71 | 118.47 |
As a result (table 1) shows in toVerticilliumdahliaActivitie Activitie S of Relative activator protein: in S-Ethyl ethylthio sulfonate=1:1~80 interval ranges, superfine chain lattice
Spore activator protein is compounded with S-Ethyl ethylthio sulfonate significantly improves the control efficiency of tomato penicilliosis, illustrates the two compounding to tomato penicilliosis
Prevention and treatment has significant synergistic effect.
(2) field efficacy verification test
Test method: it at the initial stage of a disease, carries out for the first time by spraying, carrying out being administered for second after 7 days immediately, each processing 4
A cell, each 20 square meter of cell.11 days investigation statistics incidences, 5 points of each cell are random before medicine and after second of medicine
Sampling, 5 plants of crops of every investigation, the lesion area for investigating every blade in whole strain account for percentage and the classification of blade area, calculate
Disease index and control efficiency.
It is expected that preventive effect (%)=X+Y-XY/100 (wherein, X, Y are single dose preventive effect)
Grade scale:
0 grade: disease-free spot；
1 grade: leaf spot lesion is less than 5, and length is less than 1cm；
3 grades: leaf spot lesion 6-10, part scab length is greater than 1cm；
5 grades: leaf spot lesion 11-25, part scab is linked to be piece, and lesion area accounts for the 10-25% of leaf area；
7 grades: leaf spot lesion 26 or more, scab is linked to be piece, and lesion area accounts for the 26-50% of leaf area；
9 grades: scab is linked to be piece, lesion area account for 50% of leaf area or more or full leaf it is withered.
1, toVerticilliumdahliaActivitie Activitie S of Relative activator protein compounds field efficacy experiment with S-Ethyl ethylthio sulfonate
2 toVerticilliumdahliaActivitie Activitie S of Relative activator protein of table and S-Ethyl ethylthio sulfonate mixture are to wheat scab control efficiency
Measurement result (table 2) shows that toVerticilliumdahliaActivitie Activitie S of Relative activator protein and compounding for S-Ethyl ethylthio sulfonate are bright to wheat scab preventive effect
It is aobvious to improve, illustrate that the two compounding has significant synergistic effect to wheat scab.
Claims (7)
1. a kind of microbicide compositions, which is characterized in that the composition includes toVerticilliumdahliaActivitie Activitie S of Relative activator protein and two kinds of S-Ethyl ethylthio sulfonate
Active component, wherein the weight ratio between two component of toVerticilliumdahliaActivitie Activitie S of Relative activator protein and S-Ethyl ethylthio sulfonate is 1:1~80.
2. microbicide compositions according to claim 1, which is characterized in that the active component toVerticilliumdahliaActivitie Activitie S of Relative activation
The weight ratio of albumen and active component S-Ethyl ethylthio sulfonate is 1:10~70.
3. microbicide compositions according to claim 1 or 2, which is characterized in that the composition is by active constituent and pesticide
The dosage form allowed on pesticide is made in auxiliary agent or auxiliary material.
4. microbicide compositions according to claim 3, which is characterized in that the composition by 1~85% parts by weight work
Property component and 99~15% parts by weight insecticides adjuvant or auxiliary material the dosage form allowed on pesticide is made.
5. microbicide compositions according to claim 3, which is characterized in that the dosage form is microemulsion, wettable powder
Agent or missible oil.
6. microbicide compositions according to claim 3 or 4, which is characterized in that the insecticides adjuvant or auxiliary material are selected from and carry
One or more of body, solvent, dispersing agent, wetting agent, adhesive, thickener, adhesive, surfactant or fertilizer.
7. purposes of the composition pesticide described in claim 1~6 any one in terms of agriculture field prevents and treats corps diseases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811233346.0A CN109287633A (en) | 2018-10-23 | 2018-10-23 | A kind of microbicide compositions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811233346.0A CN109287633A (en) | 2018-10-23 | 2018-10-23 | A kind of microbicide compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109287633A true CN109287633A (en) | 2019-02-01 |
Family
ID=65157587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811233346.0A Withdrawn CN109287633A (en) | 2018-10-23 | 2018-10-23 | A kind of microbicide compositions |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109287633A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102405938A (en) * | 2011-09-21 | 2012-04-11 | 浙江龙游东方阿纳萨克作物科技有限公司 | Wettable powder of alternaria tenuissima activator protein-validamycin and application |
-
2018
- 2018-10-23 CN CN201811233346.0A patent/CN109287633A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102405938A (en) * | 2011-09-21 | 2012-04-11 | 浙江龙游东方阿纳萨克作物科技有限公司 | Wettable powder of alternaria tenuissima activator protein-validamycin and application |
Non-Patent Citations (1)
| Title |
|---|
| 李克昌等: "《小麦赤霉病及其防治》", 31 May 1965, 上海科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105660659B (en) | A kind of microbicide compositions | |
| CN106942240B (en) | A kind of microbicide compositions comprising emodin derivates and benzoisothiazolinone | |
| CN101347116A (en) | Complex pesticide of osthole and agricultural antibiotic and uses thereof | |
| CN106719646A (en) | A kind of microbicide compositions comprising anthraquinone analog compound and methoxy acrylic | |
| CN105010357B (en) | Bactericidal composition and its application | |
| CN106070245B (en) | A kind of microbicide compositions | |
| CN109315400A (en) | A kind of microbicide compositions | |
| CN106561720B (en) | The bactericidal composition of class containing benzoisothiazolinone and toVerticilliumdahliaActivitie Activitie S of Relative activator protein | |
| CN106259366B (en) | A kind of microbicide compositions | |
| CN109938045A (en) | Composition pesticide containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion | |
| CN102696624A (en) | Bactericidal composition containing difenoconazole and kresoxim-methyl | |
| CN104488893B (en) | A kind of complex composition and preparation of the azoles of bacterium containing methylsulfonyl and plant growth regulator | |
| CN106857511A (en) | A kind of microbicide compositions comprising emodin derivates Yu pyrazol acid amide compounds | |
| CN109329281A (en) | A kind of microbicide compositions containing Physcion and tetramycin | |
| CN106234392B (en) | A kind of microbicide compositions | |
| CN109845736A (en) | Bactericidal composition containing toVerticilliumdahliaActivitie Activitie S of Relative activator protein and Physcion | |
| CN108338165A (en) | A kind of microbicide compositions including emodin derivates and polysaccharide | |
| CN104488963B (en) | Compound composition with methanesulphonyl myclobutanil and organic copper bactericide and preparation | |
| CN106376578B (en) | A kind of microbicide compositions | |
| CN106259384B (en) | A kind of microbicide compositions | |
| CN109287633A (en) | A kind of microbicide compositions | |
| CN105961413A (en) | Bactericidal composition containing oxolinic acid and bromothalonil | |
| CN109526958A (en) | Microbicide compositions containing rheum emodin and metconazole | |
| JP2022537465A (en) | Synergistic antiseptic composition | |
| CN106719647A (en) | A kind of microbicide compositions comprising anthraquinone analog compound and metrafenone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190201 |
|
| WW01 | Invention patent application withdrawn after publication |