CN109224011A - Control the diseases related integration of drinking and medicinal herbs composition and preparation method thereof of backbone - Google Patents
Control the diseases related integration of drinking and medicinal herbs composition and preparation method thereof of backbone Download PDFInfo
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- CN109224011A CN109224011A CN201811347805.8A CN201811347805A CN109224011A CN 109224011 A CN109224011 A CN 109224011A CN 201811347805 A CN201811347805 A CN 201811347805A CN 109224011 A CN109224011 A CN 109224011A
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- decoction
- water
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- backbone
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Abstract
The invention discloses a kind of integration of drinking and medicinal herbs compositions that prevention and treatment backbone is diseases related, it is raw material by pueraria lobata, semen ziziphi spinosae, fructus lycii, Radix Astragali, schizonepeta, peppermint, chrysanthemum, jujube, rose, coloured malt, pawpaw, semen coicis, fingered citron, Siraitia grosvenorii, above-mentioned raw materials are weighed to above-mentioned Chinese medicine in proportion, impregnate half an hour, then one water decoction 2 times is reinstated, from boiling timing each half an hour, 10 times with water quality for total quality of medicinal material are decocted for the first time, are decocted for the second time with 8 times that water quality is total quality of medicinal material；Finally merge decoction liquor twice, concentration is prepared.
Description
Technical field
The present invention relates to a kind of integration of drinking and medicinal herbs compositions and preparation method thereof that backbone is diseases related, belong to functional food
With tcm health preserving rehabilitation field.
Background technique
In internet and artificial intelligence increasingly developed today, mental labour increasingly replaces physical strength to work, and people are continuously solid
The working method for determining position easily induces the strain of backbone, leads to " muscle job-hopping, dislocation of bone ".Backbone is diseases related refer to neck,
The bone of thoracolumbar vertebrae, joint, interverbebral disc and vertebra week soft tissue is damaged or degenerative change, under the conditions of certain inducement, occur
Spinal joint dislocation, disc herniation, ligament calcification or osteoproliferation, soft tissue swelling, spasm or adhesion etc. by vertebra, directly or
The generations such as nerve root, intra-and extraspinal blood vessel, spinal cord or sympathetic nerve are stimulated or oppressed indirectly, are caused other than spinal injury illness
Multisystem sings and symptoms disease.The diseases related most common symptom of backbone is lumbago, cervical vertebra pain, insomnia, eyesight
Decline, pharyngalgia, gastrointestinal dysfunction, hypertension, palpitaition etc..At the diseases related proposition of medical field backbone only 30 years,
But this kind of diseases are more and more common.By taking non-specific lumbago as an example, a research report, global Adult chronic's lumbago
Illness rate: 1 month illness rate is 23.2%, and 1 year illness rate is 38%, lifetime prevalence 38.9%.Backbone correlation
Only lumbago one huge Medical Consumption of just having taken to European and American developed countries in disease, in the current fast, economical development in China
In the process of quick aging, backbone it is diseases related suffer from degree as one can imagine.
The acupuncture of the spinal rotation massage, anodyne and Chinese medicine in west, massaging has in the diseases related diagnosis and treatment of backbone
Certain effect, but for individual, these methods need the continued treatment of doctor and biggish input to be possible to obtain
Good effect.How to find it is a kind of it is simpler, just, method that is honest and clean, testing carry out this kind of illness of rehabilitation?
In terms of tcm causa morbi theory, backbone is diseases related, and why high-incidence reason is mainly there are three aspect: first is that exogenous disease
Wind-cold damp pathogen, yang-energy are impaired；Second is that disease resulting from over-exertion, keeps mechanical posture, inappropriate posture, excessive weight bearing etc. for a long time
Cause joint of vertebral column unbalance；Third is that aging, proposed in Huangdi's Internal Classics, " man-year 50, irritability beginning decline ", joint of vertebral column be muscle,
Bone, meat interlock most complicated joint system, the diseases related most high-incidence age level of backbone just just at 50 years old or so, this
Coincidence a kind of absolutely not.
In terms of interpretation of the cause, onset and process of an illness level, in the center of human body behind, be that human body is most important supports, balances, protection system backbone, superintends and directs
Therethrough, the urinary bladder channel of foot-Taiyang is distributed in two sides to arteries and veins, and the relationship of this two passages through which vital energy circulates and backbone is the closest.Governor vessel and sufficient sun wing
Guang is all that human body runs and dissipates the most important passages through which vital energy circulates of yang-energy, wherein the yang-energy of the current the whole body of governor vessel, the main spreading of bladder meridian
Defend gas.Therefore the rehabilitation for declaring the yang-energy of logical governor vessel and bladder meridian diseases related for backbone has important value.
" blood stored in the liver, bloodhousing mood ", " the sleeping then blood of people is attributed to liver ", sleep has close relationship with liver.In the state of sleep,
Backbone is possible to most loosen, and sufficient, efficient, depth sleep can promote the self-regeneration of backbone.Liver -- sleep -- backbone
Between be closely connected.
Be based on the understanding to the pathogen and pathology of tcm theory of disease about spine, applicant in clinical position gradually
A set of positive ridge therapy of calming the nerves is found out for treating this kind of disease, this method system gets rid of the mistake that foot pain for the treatment of the head when the head aches cures foot
Accidentally orientation treatment, can search for the primary cause of disease in treatment, and improve curative effect, improve the comfort level of patient and reduce medical expense.The Tang Dynasty doctor Sun Si
Far away to think, " curing the disease must provide in food, be upper work if disease can be sent with food." with the drug of integration of drinking and medicinal herbs, according to certain Chinese medicine
Therapy and prescription rule, create a kind of novel foodstuff that can contribute to prevent disease about spine, are original intentions of the invention.
Summary of the invention
The first technical problem to be solved by the present invention be to provide it is a kind of control backbone it is diseases related integration of drinking and medicinal herbs combination
Object and preparation method thereof, the two of technical problem to be solved are to provide the preparation method and application of the composition.
In order to solve the above-mentioned technical problem, The technical solution adopted by the invention is as follows:
Control the diseases related integration of drinking and medicinal herbs composition of backbone, with pueraria lobata, semen ziziphi spinosae, fructus lycii, Radix Astragali, schizonepeta, peppermint,
Chrysanthemum, jujube, rose, coloured malt, pawpaw, semen coicis, fingered citron, Siraitia grosvenorii are raw material, are in mass ratio 4:3:2:3:2:1:
2:2:1:2:2:2:2:1 is prepared.
The diseases related integration of drinking and medicinal herbs composition and preparation method thereof of backbone is controlled, is to weigh above-mentioned Chinese medicine in proportion first
Material impregnates half an hour, then one reinstates water decoction 2 times, and from boiling timing each half an hour, it is total for being decocted for the first time with water quality
10 times of quality of medicinal material, second of 8 times decocted with water quality for total quality of medicinal material；Finally merge decoction liquor twice, concentration system
It is standby to form.
Chinese medicine composition of the present invention or the Chinese medicine composition can be answered with pharmaceutically acceptable pharmaceutical carrier
It is used to prepare the diseases related pharmaceutical preparation of prevention and treatment backbone.The pharmaceutical preparation can be any pharmaceutical dosage form, this
A little dosage forms include: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, take orally
Liquid, mouth containing agent, granule, electuary, pill, powder, paste, sublimed preparation, suspension, pulvis, solution, injection, suppository, ointment
Agent, emplastrum, creme, spray, drops, patch；It is preferred that peroral dosage form, such as: capsule, tablet, oral solution, granule, ball
Agent, powder, sublimed preparation, paste etc..The peroral dosage form can contain common excipient, such as adhesive, filler, dilution
Agent, tablet agent, lubricant, disintegrating agent, colorant, flavoring agent and wetting agent when necessary can be coated tablet.Suitable fills out
Filling agent includes cellulose, mannitol, lactose and other similar fillers；Suitable disintegrating agent includes starch, polyethylene pyrrole
Pyrrolidone and starch derivatives, such as sodium starch glycollate；Suitable lubricant includes, such as magnesium stearate；Suitable medicine
The acceptable wetting agent of object includes lauryl sodium sulfate.
Chinese medicine composition of the invention is by pueraria lobata, semen ziziphi spinosae, fructus lycii, Radix Astragali, schizonepeta, peppermint, chrysanthemum, jujube, rose
Rare flower, coloured malt, pawpaw, semen coicis, fingered citron, Siraitia grosvenorii composition.Semen ziziphi spinosae nourishing the liver blood-enriching tranquillizing, pueraria lobata rising Yang expelling pathogenic factors from muscles and skin relax in side
Muscle is altogether monarch drug in a prescription；Schizonepeta, the analgesic of peppermint relieve heat, Radix Astragali, rose inrigorating qi and promoting blood circulation, four medicines are ministerial drug altogether；Chrysanthemum clears liver and improve vision,
Siraitia grosvenorii clearing heat, relieving sore-throat, fingered citron, coloured malt invigorating spleen and soothing liver help digestion, and pawpaw, semen coicis invigorating spleen for diuresis, relaxing muscles and tendons analgesic, fructus lycii are mended
The all medicines of liver and kidney benefiting are adjutant, and jujube coordinating the drug actions of a prescription is to make medicine.Full side's effect is ataralgesia, and the positive ridge of relaxing muscles and tendons has help liver
Spleen kidney delays muscles and bones aging, promoting blood circulation and stopping pain, the effect of adjustment joint of vertebral column balance.The symptom mainly improved are as follows: insomnia, neck
By force, lumbago, hypopsia, have sore throat, palpitaition, abdominal distension, lassitude, lassitude and weak, dizziness etc..
Recipe of this pharmaceutical composition in classical Chinese medicine works according to the disease feature of modern, and combines modern
The achievement of traditional Chinese medicine research, inventive combination form, through clinic be widely used verifying it is significant in efficacy for disease about spine, for
Single lumbago, insomnia, cervical spondylosis, Functional Gastrointestinal Disease, vision disorder, chronic pharyngitis, osteoporosis, chronic Bones and joints
Scorching and backbone retrogression pathological changes all have a better effect.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, and instead of all the embodiments, based on the embodiments of the present invention, this field is common
Technical staff's every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
For a better understanding of the present invention, it further illustrates combined with specific embodiments below.
Embodiment 1
A kind of integration of drinking and medicinal herbs composition that prevention and treatment backbone is diseases related, which is characterized in that the composition is with pueraria lobata, wild jujube
Benevolence, fructus lycii, Radix Astragali, schizonepeta, peppermint, chrysanthemum, jujube, rose, coloured malt, pawpaw, semen coicis, fingered citron, Siraitia grosvenorii are original
Material, and the mass ratio of above-mentioned raw materials is 4:3:2:3:2:1:2:2:1:2:2:2:2:1.
Its preparation step is as follows:
(1) it weighs and impregnates: weighing above-mentioned Chinese medicine according to the above ratio, be placed in 20-40 degree water and impregnate half an hour；
(2) decoct: by through step (1) impregnate after medical fluid and the dregs of a decoction add water to cook together 2 times, from boiling in decoction process
Start timing, boiling decocts half an hour every time, after will decoct resulting decoction liquor and filter out.
(3) preparation: the decoction liquor twice in mixing step step (2), and mixed decoction liquor is concentrated into step (2)
Agent is prepared with excipient in 1st/10 to ten/15ths of middle amount of water.
It is further used as preferably, first time decoction 10 times that water quality is medicinal material total quality, water quality is used in second of decoction
Amount is 8 times of medicinal material total quality.
It is further used as preferably, the excipient is at least adhesive, filler, diluent, tablet agent, lubricant, collapses
Solve one of agent, colorant, flavoring agent and wetting agent.
It is further used as preferably, the filler is cellulose, mannitol, lactose；The disintegrating agent includes starch, gathers
Vinylpyrrolidone and starch derivatives；The lubricant is magnesium stearate；, the wetting agent includes lauryl sodium sulfate.
Embodiment 2
It is a kind of to control the diseases related integration of drinking and medicinal herbs composition and preparation method thereof of backbone:
Take 400 grams of Chinese medicine pueraria lobata, 300 grams of semen ziziphi spinosae, 200 grams of fructus lycii, 300 grams of Radix Astragali, 200 grams of schizonepeta, peppermint 100
Gram, 200 grams of chrysanthemum, 200 grams of jujube, 100 grams of rose, 200 grams of coloured malt, 200 grams of pawpaw, 200 grams of semen coicis, fingered citron 200
Gram, 100 grams of Siraitia grosvenorii, from boiling timing each half an hour, it (is the 10 of total quality of medicinal material that first time decoction, which is 25kg with water quality,
Times), second of decoction is 20kg (for 8 times of total quality of medicinal material) with water quality, merges decoction liquor twice, be concentrated for 2500mL it is dense
Contracting liquid, patient take 2 concentrates daily, and 9 points of the morning are taken 30ml, take 30ml at 9 points at night, 20 days as a treatment course are total
Treat two courses for the treatment of.Or it is made into capsule, tablet, oral solution, granule, pill, powder, sublimed preparation, paste.
Clinical effectiveness verifying
1. case source
120 selected patients are recruited in Hubei Provincial Hospital of TCM's massage rehabilitation department, being mainly included in standard is with lumbago, cervical vertebra
Discomfort, insomnia, gastrointestinal dysfunction, palpitaition, tired etc. are chief complaint, and the trouble of other serious organic diseases is excluded through CT examination
Person.In 120 patients, women 60, male 60.Patient age is between 16-73 years old, average age 38.8 ± 3.73.
2. standards of grading
Insomnia and insomnia degree are judged with Athens insomnia scale, evaluate patient body pain with visual analogue scales
Degree observes patients' blood, heart rate, electrocardiogram, stool and urine shape.
VAS method, i.e. visual analogue scales, be at present it is clinically most common, be specifically about 10cm's using one
Walk scale, indicates 10 scales on one side, and both ends show 0 and 10 respectively, 0 represent it is painless, 10 represent it is insufferable most acutely
Pain, when clinical use, by the graduated one side of ruler back to patient, oneself pain journey can be represented by allowing patient to mark on paper
The corresponding position of degree, doctor provide corresponding pain scores according to the position that it is marked.
Athens insomnia scale (AIS)
Fill in a form people: date of filing: the evaluation
This table is mainly used for recording your self-assessment to the sleep disturbance encountered.The problem of for being listed below, such as
Fruit is per week within past 1 month at least to occur 3 times with you, just woulds you please beat " √ " on corresponding " ":
Scale totally 8 entries, every from without to being seriously divided into the scoring of 0,1,2,3 level Four
(total score is less than 4: without sleep disturbance；If total score is in 4-6: suspicious insomnia；If total score is at 6 points or more: insomnia).
3. treatment condition
Patient takes 2 concentrates daily, and 9 points of the morning are taken 30ml, takes 30ml at 9 points at night, 20 days as a treatment course,
Two courses for the treatment of are treated altogether.
4. curative effect determinate standard
It is effective: have a sleepless night after treatment scale integral and 2/3 or 2/3 or more the decline compared with pre-treatment of pain integral.
It is effective: have a sleepless night after treatment scale integral and the decline 1/3~2/3 compared with pre-treatment of pain integral.
It is invalid: have a sleepless night after treatment scale integral and 1/3 or less the decline compared with pre-treatment of pain integral.
5. result counts
After two course of therapy, in 120 patients, effective 80, effective 36, invalid 4, total effective rate reaches
96.67%.
6. typical case
River, female 37 years old, are engaged in scientific research.Uneasy sleeping at night, dreaminess, lumbago half a year.Closely over the past half year, uneasy sleeping at night
It gradually aggravates, rear tired from morning, lassitude, backache on daytime, neck pain are uncomfortable, pharyngalgia, depending on mist, abdominal distension, diarrhea with loose stool.Tongue
Light red tongue fur is thin micro- greasy, deep thready pulse.Pain visual score 6 divides, scale score 18 of having a sleepless night.After taking ridge 1 course for the treatment of of strong concentrate,
Symptom disappears substantially, and pain scores 1 are divided, and insomnia scale score 5 divides, and clinical efficacy is effective.
Rely certain, female, 41 years old, accounting.Dizziness, backache, freckle 3 years.Over 3 years, patient falls asleep's difficulty is gradually aggravated, Chang Zao
It wakes up, rear tired from morning, lassitude, it is difficult to adhere to work, backache on daytime, usually dizzy discomfort；Facial freckle increases, menstrual flow
It reduces, it is dilute when dry when stool, often there are diarrhea or constipation.Cervical curvature changes, fourth, fifth, six cervical vertebrae hyperosteogenies；Thoracic vertebrae
Disordered small joint.Pale tongue is fat tender, and tongue fur is thin satiny, deep thready pulse.Pain visual score 6 divides, scale score 17 of having a sleepless night.It is strong to take ridge
After two courses for the treatment of of concentrate, every symptom is significantly improved, and the state of mind improves.Pain scores 2 are divided, and insomnia scale score 5 divides, and are faced
Bed curative effect is effective.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (5)
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097560A (en) * | 1993-09-08 | 1995-01-25 | 北京医科大学亿康科技开发总公司 | In, the health of older persons nutrient composite |
| CN102247539A (en) * | 2010-05-17 | 2011-11-23 | 王红年 | Chinese medicinal health care wine |
| CN105327092A (en) * | 2015-12-03 | 2016-02-17 | 章程鹏 | Traditional Chinese medicine composition for treating cervicogenic insomnia and application thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1097560A (en) * | 1993-09-08 | 1995-01-25 | 北京医科大学亿康科技开发总公司 | In, the health of older persons nutrient composite |
| CN102247539A (en) * | 2010-05-17 | 2011-11-23 | 王红年 | Chinese medicinal health care wine |
| CN105327092A (en) * | 2015-12-03 | 2016-02-17 | 章程鹏 | Traditional Chinese medicine composition for treating cervicogenic insomnia and application thereof |
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