CN108835262A - A kind of modulation milk powder and preparation method thereof improving memory - Google Patents
A kind of modulation milk powder and preparation method thereof improving memory Download PDFInfo
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The present invention provides a kind of modulation milk powder and preparation method thereof for improving memory, and the modulation milk powder component is as follows:The full-cream lotion of 40-50 parts of whole-fat milk powder or same dry matter, the separated milk of 17-25 parts of skimmed milk powder or same dry matter, 15-23 parts of whey powder, glucose syrup solids or 5-15 parts of lactose, 2-5 parts of vegetable oil, 0.2-3 parts of fish oil extract, yolk powder 0.1-1 parts of hydrolysis, 0.01-2 parts of integration of drinking and medicinal herbs object, 0.01-3 parts of dietary fiber, 0.2-2 parts of composite mineral matter, 0.01-0.15 parts of multi-vitamins, 0.01-0.5 parts of sialic acid, 0.025-0.6 parts of phosphatidylserine, 0.002-0.008 parts of zeaxanthin.This modulation milk powder plays the mutually collaboration promotion simultaneously of respective function, the nutrition of effective supply cerebral central nervous system and oxygen by various composition in vivo, enhances brain memory ability, improves brain function comprehensively.
Description
Technical field
The present invention relates to modulation milk powder technical fields, particularly, are related to a kind of modulation milk powder and its system for improving memory
Preparation Method.
Background technique
Alzheimer disease (Alzheimer disease, AD), is called senile dementia, is a kind of central nervous system
System degenerative disease, insidious onset, the course of disease are in chronic progressive, are senile dementia one of the most common type types.With population old-age group
Change, the disease incidence of senile dementia (AD) is consequently increased, and is to cause the elderly dead after tumour, heart disease, cerebrovascular disease
The fourth-largest cause of disease.The drug for the treatment of senile dementia mainly has choline enzyme inhibitor at present, and cerebral vasodilator is eaten excessively,
There may be the potential danger for generating adverse reaction.
Brain is that human body carries out the most accurate organ of thinking activities, the functions such as supervisor mankind study, thinking, memory.Wherein,
Memory is the reproduction to former things and experience, including memorize, keeps, re-recognizes and recall four basic processes.Hypomnesia is
It is the generally decline of Four processes above.Less serious case shows the impaired memory to nearly thing, such as forgets the book just read, the people just met.
Then remote memory also declines when serious, such as can not recall the learning experiences of oneself.
Hypomnesia is very common for the elderly, mostly due to neurasthenia and senile dementia patient.A middle-aged person and
The failure of memory of teenager etc. is far smaller than the elderly, typically since the factors such as learning life cause spiritual high-pressure
Or continuous overstrain one's nerves make caused by neural fatigue.Therefore enhancing is very heavy to the nutrition of cerebral central nervous system, oxygen supply
It wants.The source of brain function is the activity of cerebral neuron, between the energy supply of neuron, necessary nutrient and neuron
The interaction of neurotransmitter has been largely fixed the vigor and human-subject test of brain.
Therefore, a kind of modulation milk powder for improving memory is developed, it is languisher edible to be applicable to each stage memory
Modulating milk powder has important value and wide market.
Summary of the invention
It is an object of that present invention to provide a kind of modulation milk powder for improving memory, solve that each stage memory is weak to ask
Topic enhances nutrition to cerebral central nervous system, oxygen supply.
To achieve the above object, the present invention provides a kind of modulation milk powder for improving memory, including following components:It is full-cream
40-50 parts of milk powder or comprising dry matter be equal to the full-cream lotion of 40-50 parts of whole-fat milk powder weight, skimmed milk powder 17-25 or comprising
Dry matter is equal to 15-23 parts of separated milk, whey powder, glucose syrup solids or the lactose 5-15 of 17-25 parts of skimmed milk powder weight
Part, 2-5 parts of vegetable oil, 0.2-3 parts of fish oil extract, yolk powder 0.1-1 parts of hydrolysis, 0.01-2 parts of integration of drinking and medicinal herbs object, diet are fine
Tie up 0.01-3 parts, 0.2-2 parts of composite mineral matter, 0.01-0.15 parts of multi-vitamins, 0.01-0.5 parts of sialic acid, phosphatidyl silk
0.025-0.6 parts of propylhomoserin, 0.002-0.008 parts of zeaxanthin.
Further, the whole-fat milk powder or full-cream lotion, skimmed milk powder or separated milk and whey powder by milk or
Person's goat milk is made；Wherein, dry matter content is 97% in the whole-fat milk powder, and dry matter content is 11.7% in full-cream lotion；
Dry matter content is 96% in the skimmed milk powder, and dry matter content is 11.7% in separated milk.
Further, the vegetable oil is one or more of corn oil, rapeseed oil, sunflower oil and coconut oil.
Further, the fish oil extract be marine fish it is heated boil, squeeze, being centrifuged, purifying, decolourizing, deodorization and
Manufactured oily liquids or powder product, the marine fish include one or more of salmon, sardine and tuna.
Further, the dietary fiber is one in oligofructose, inulin, yeast beta-dextran or avenabeta glucosan
Kind is several.
Further, the integration of drinking and medicinal herbs object is rhizoma polygonati, Chinese yam, fructus alpiniae oxyphyllae, Poria cocos, jujube, semen ziziphi spinosae, arillus longan, Chinese holly
One of matrimony vine, walnut kernel or several manufactured powder products.
The present invention also provides a kind of preparation methods of modulation milk powder for improving memory, and preparation method is the compound work of dry and wet
Skill or dry mixing process.
Further, the dry and wet combination process specifically includes following steps：
Step 1：The preparation of integration of drinking and medicinal herbs object：It is crushed using integration of drinking and medicinal herbs substance of the pulverizer to predetermined ratio, it will
The raw material of crushing is placed in container, and ethyl alcohol is added, impregnated, extracted, and is merged alcohol extract and is concentrated into no alcohol taste；Material residue is flung to
After ethyl alcohol, water is added to be impregnated, soak is decocted, filtering removal raw material leaves and takes decoction liquor；Alcohol extracting after merging concentration
Liquid and decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder product is finally prepared with 60-80 mesh point；
Step 2：Ingredient：By predetermined ratio by whole-fat milk powder, skimmed milk powder, whey powder, glucose syrup solids or lactose,
It is added in 3-4 times 40-50 DEG C of weight of pure water after integration of drinking and medicinal herbs object, dietary fiber and hydrolysis yolk powder mixing, or by pre-
Whey powder, glucose syrup solids or lactose, integration of drinking and medicinal herbs object, dietary fiber and hydrolysis yolk powder are mixed and are directly added by certainty ratio
Into 40-50 DEG C of full-cream lotion and separated milk, resulting first mixed material squeezes into temporary storage tank I after being stirred uniformly；It takes
The fish oil extract of predetermined ratio is added in predetermined ratio vegetable oil uniformly mixed and the first mixed material institute after mixing
It obtains the second mixed material and squeezes into temporary storage tank II；By predetermined ratio by multi-vitamins, composite mineral matter use respectively 10 times 40 DEG C~
50 DEG C of pure water are uniformly mixed after dissolving in advance with the second mixed material, and gained third mixed material squeezes into temporary storage tank III；
Step 3：Shearing and filtering：III third mixed material of temporary storage tank is poured into high speed by dosing pump or directly
After shearing tank, stirring after ten minutes, gets to standardization cylinder through duplex strainer and obtains the 4th mixed material；
Step 4：Homogeneous：4th mixed material progress homogeneous is obtained into the 5th mixed material；
Step 5：Sterilization：5th mixed material is sterilized；
Step 6：Concentration：The 5th mixed material after sterilization is concentrated into 20-24 ° of B é, obtains the 6th mixed material；
Step 7：Spray drying：It is spray-dried the 6th mixed material to obtain the 7th mixed material；
Step 8：Bean jelly：7th mixed material is cooled down into room temperature through fluidized bed, water content is 2.5- in material
4.0%；
Step 9：Mixing：By predetermined ratio addition phosphatidylserine, zeaxanthin and sialic acid in three-dimensional mixer
It is uniformly mixed and obtains modulation milk powder.
Further, the dry mixing process specifically includes following steps：
Step A：The preparation of integration of drinking and medicinal herbs object：It is crushed using integration of drinking and medicinal herbs substance of the pulverizer to predetermined ratio, it will
The raw material of crushing is placed in container, and ethyl alcohol is added, impregnated, extracted, and is merged alcohol extract and is concentrated into no alcohol taste；Material residue is flung to
After ethyl alcohol, water is added to be impregnated, soak is decocted, filtering removal raw material leaves and takes decoction liquor；Alcohol extracting after merging concentration
Liquid and decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder product is finally prepared with 60-80 mesh point；
Step B：Level-one is dry-mixed, by the whole-fat milk powder of predetermined ratio, integration of drinking and medicinal herbs object, fish oil extract, hydrolysis yolk powder,
Dietary fiber, phosphatidylserine, sialic acid, zeaxanthin, multi-vitamins, composite mineral matter are put into three-dimensional mixer and mix
Conjunction uniformly obtains first material, by first material through two-phase transportation into high-speed mixer；
Step C：Second level is dry-mixed, by predetermined ratio by skimmed milk powder, whey powder, glucose syrup solids or lactose, through embedding
Plant oil powder, put into high-speed mixer in be uniformly mixed with first material to get modulation milk powder of the invention.
Fish oil is the street cleaner of human vas, is rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid ((DHA) etc.
Omega-3 polyunsaturated fatty acids, the total content of main component EPA and DHA are generally 34% or more, this kind of polyunsaturated fat
Acid has effects that prevention of arterial hardening, headstroke, hypertension, coronary heart disease and cardiopathic.In recent years, research finds EPA and DHA
Equal omega-3 polyunsaturated fatty acids have the function of improving cerebral function especially have the function of improving brain memory.
Yolk powder is hydrolyzed, lecithin rich in after being enzymatically decomposed, can produce acetic acid choline abundant, into blood
Liquid can reach in brain tissue quickly again, can enhance human body memory.Hydrolysis yolk powder can also activate bone itself motive power,
Promote the elongation of bone；Promote the calcareous heavy knot of bone, maintains the balance of bone ingredient.
In integration of drinking and medicinal herbs substance, Fructus Alpinae Oxyphyllae extract can be obviously improved ability of learning and memory, there is nootropic effect.In jujube
Containing carbohydrate, protein, fat, organic acid, there is benefiting action to brain.Longan is also known as longan, warm-natured sweet in flavor, heart-spleen boosting, mends
Qi and blood；With good nourishing benefiting action, it can be used for insomnia caused by heart and spleen deficiency, insufficiency of vital energy and blood, amnesia, palpitation with fear, dizziness
Equal diseases, can also treat weak after illness or aneuria.Walnut kernel contains unsaturation necessary to more protein and human nutrition
Fatty acid, these ingredients are all important substance needed for cerebral tissue cell metabolism, and energy nursing brain cells enhance brain function.
Phosphatidylserine, also known as composite nerve acid are extracted by crude soya bean oil expression residue, are the active matters of cell membrane
Matter is particularly present in brain cell.Its function mainly improves nerve cell function, adjusts the conduction of nerve impulse, promotes
Brain memory function can run through blood-brain barrier since it is with very strong lipophilicity, after absorption and enter brain, play easypro
Slow vascular smooth muscle cells, increase the effect of brain blood supply.
Sialic acid scientific name is the derivative of 9- carbon monosaccharide N-acetyl-neuraminate, it can make saliva generate smooth feeling
Negatively charged ions.Not only evidence plays the role of " inducing " invasion germ for it, and cognition at present is the transmitting mediator of gangliosides, and
It and is the component part of brain.Sialic acid and children's early intelligence development level in breast milk have direct relation, and sialic acid can promote
Information into cerebral nerve Fine born of the same parents conveys speed to improve the reaction of brain by the interaction with brain Fine after birth and cynapse
Speed.Therefore supplement sialic acid can increase brain intelligence development, to improve memory.
The chemical name of zeaxanthin is (3R, 3'R)-dihydroxy-beta carotene, and zeaxanthin is that only have in crystalline lens
One of 2 Carotenoids, have 11 conjugated double bonds in its molecule, and hydroxyl is had in tail end group, this structure makes it
With stronger oxidation resistance.Studies have shown that zeaxanthin takes in high crowd, the crowd than low intake suffers from cataract
Possibility can reduce by 19%~22%.Prevent the effect of Age related macular area lesion.Zeaxanthin itself has very high nutriture value
Value can be converted to biologically active vitamin A after edible in human liver, and vitamin A can promote the development of brain.Corn
Yellow matter influences an important factor for macular pigment optical density (OD) size (MPOD), macular pigment optical density (OD) size (MPOD) and suffers from
The cognition of the people of mild cognitive impairment is related, and macular pigment optical density (OD) size (MPOD) is unique and healthy elderly can
Visual space and the related factor of interpretability.
The invention has the advantages that：
It is same containing fish oil extract, hydrolysis yolk powder, phosphatidylserine, sialic acid, medicine food that the present invention provides one kind
Source object, zeaxanthin, vitamin (A, E, C) and microelement (calcium, iron, zinc, magnesium, selenium) are with modulating ligand made of special ratios
Square milk powder, playing respective function in vivo by various nutritional ingredients, mutually collaboration promotes simultaneously, effective supply brain centres mind
Nutrition and oxygen through system improve information transmission speed, enhance brain memory ability, improve brain function comprehensively, be applicable to
Each stage memory is languisher edible.The modulation milk powder not only has improvement result to memory, while having and increasing body bone
The effect of bone density and prevention visual impairment.
Other than objects, features and advantages described above, there are also other objects, features and advantages by the present invention.
The present invention is further detailed explanation below.
Specific embodiment
The embodiment of the present invention is described in detail below, but the present invention can be limited and be covered according to claim
Multitude of different ways implement.
Embodiment 1:
A kind of modulation milk powder improving memory, its raw material includes following components by weight percentage:Raw milk powder：
42.5 parts, skimmed milk powder：20 parts, bovine whey powder：17.5 parts, glucose syrup solids：12 parts, corn oil：3 parts, hydrolysis yolk
Powder：0.7 part, fish oil extract：1.3 parts, inulin：1.14 parts, walnut kernel：0.1 part, jujube：0.3 part, arillus longan：0.1 part, benefit
Intelligence benevolence：0.2 part, composite mineral matter：1 part, multi-vitamins：0.06 part, phosphatidylserine：0.04 part, sialic acid：0.055
Part, zeaxanthin：0.005 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：70%, acetic acid is tieed up
Raw element A：0.67%, Vitamin D3：0.011%, dl- ɑ-D-α-tocopherol acetate：29.319%.
The composite mineral matter is formed by following components and weight percent mixture:Calcium carbonate：81.396%, sulfuric acid is sub-
Iron：1.8%, zinc sulfate：0.8%, magnesium sulfate：16%, sodium selenite：0.004%.
The modulation milk powder of the present embodiment is made of wet-dry change combination process, specifically includes following steps:
Step 1：The preparation of integration of drinking and medicinal herbs object：Using pulverizer to the walnut kernel of predetermined ratio, jujube, arillus longan, fructus alpiniae oxyphyllae
It is crushed, the raw material of crushing is placed in container, 3-5 times of the 60-80% ethyl alcohol that weight is raw material weight is added, is soaked
Bubble extracts 2 times, merges alcohol extract and is concentrated into no alcohol taste；After material residue flings to ethyl alcohol, 6-8 times that weight is raw material weight is added
Water impregnated, decoction 30-60min carried out to soak, filtering removal raw material leaves and takes decoction liquor；Alcohol after merging concentration
Extract and decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder is finally prepared with 60-80 mesh point.
Step 2：Ingredient:By predetermined ratio by raw milk powder, skimmed milk powder, bovine whey powder, glucose syrup solids,
3-5 times 40-50 DEG C of weight of pure water is added after inulin, integration of drinking and medicinal herbs object and hydrolysis yolk powder mixing and is stirred uniformly rear institute
The first mixed material obtained squeezes into temporary storage tank I；It takes the fish oil extract of predetermined ratio to be added in predetermined ratio corn oil to mix
Uniformly the second mixed material of gained squeezes into temporary storage tank II after mixing with the first mixed material；Compound dimension is given birth to by predetermined ratio
Element, composite mineral matter are uniformly mixed after being dissolved in advance with 8-10 times of 45 DEG C of pure water respectively with the second mixed material, gained third
Mixed material squeezes into temporary storage tank III.
Step 3：Shearing and filtering：III third mixed material of temporary storage tank is poured into high speed by dosing pump or directly
After shearing tank, stirring after ten minutes, gets to standardization cylinder through duplex strainer and obtains the 4th mixed material.Standardization cylinder stirring is answered
Persistently it is kept stirring state, it is ensured that be uniformly mixed with material milk and ingredient is prevented to be layered.
Step 4：Homogeneous：4th mixed material is subjected to homogeneous, homogenizing temperature is 60-65 DEG C and pressure is 18-
20MPa obtains the 5th mixed material.
Step 5：Sterilization：5th mixed material is sterilized, sterilization temperature sterilizes 20-25 under conditions of being 89 ± 2 DEG C
Second.
Step 6：Concentration：The 5th mixed material after sterilization is concentrated into 20 ° of B é, obtains the 6th mixed material.
Step 7：Spray drying：It is spray-dried the 6th mixed material to obtain the 7th mixed material.
Step 8：Bean jelly：7th mixed material is cooled down into room temperature through fluidized bed.
Step 9：Mixing：By mixed in predetermined ratio addition phosphatidylserine, sialic acid, zeaxanthin three-dimensional mixer
It closes and uniformly obtains modulation milk powder.
The modulation milk powder of the present embodiment can also be packed accordingly according to actual needs, specifically using:Vacuum
Nitrogen charging or nitrogen mixing carbon dioxide carry out controlled atmospheric packing, final packaging product are obtained, marked as MKP-1, as test sample；
Embodiment 2:
A kind of modulation milk powder improving memory, its raw material includes following components by weight percentage:Full-cream sheep cream：
331.6 parts (being equivalent to 40 parts of full-cream sheep milk powder), degreasing sheep cream：180.5 parts of (being equivalent to 22 parts of degreasing sheep milk powder), sheep wheys
Powder：18.3 parts, lactose：8 parts, oligofructose：2 parts, corn oil：4 parts, hydrolysis yolk powder：0.9 part, rhizoma polygonati：0.5 part, fructus lycii
Son：0.2 part, Poria cocos：0.1 part, Chinese yam：0.2 part, fish oil extract：2 parts, complex mineral：1 part, multi-vitamins：0.1 part,
Phosphatidylserine：0.4 part, sialic acid：0.292 part, zeaxanthin：0.008 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：80%, acetic acid is tieed up
Raw element A：0.4%, Vitamin D3：0.01%, dl- ɑ-D-α-tocopherol acetate：19.59%.
The composite mineral matter is formed by following components and weight percent mixture:Calcium carbonate：81.396%, sulfuric acid is sub-
Iron：1.8%, zinc sulfate：0.8%, magnesium sulfate：16%, sodium selenite：0.004%.
The modulation milk powder of the improvement memory of the present embodiment is made of wet-dry change combination process, specifically includes following step
Suddenly:
Step 1：The preparation of integration of drinking and medicinal herbs object：The rhizoma polygonati of predetermined ratio, fructus lycii, Poria cocos, Chinese yam are carried out using pulverizer
It crushes, the raw material of crushing is placed in container, 3-5 times of the 60-80% ethyl alcohol that weight is raw material weight is added, impregnated,
It extracts 2 times, merge alcohol extract and is concentrated into no alcohol taste；After material residue flings to ethyl alcohol, 6-8 times of the water that weight is raw material weight is added
It is impregnated, decoction 30-60min is carried out to soak, filtering removal raw material leaves and takes decoction liquor；Alcohol extract after merging concentration
And decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder is finally prepared with 60-80 mesh point.
Step 2：Ingredient:By predetermined ratio by whey powder, glucose syrup solids or lactose, integration of drinking and medicinal herbs object, dietary fiber
It is added directly into 40-50 DEG C of full-cream sheep cream and degreasing sheep cream with hydrolysis yolk powder mixing, resulting the after being stirred uniformly
One mixed material squeezes into temporary storage tank I；Take the fish oil extract of predetermined ratio be added in predetermined ratio corn oil be uniformly mixed with
The second mixed material of gained squeezes into temporary storage tank II to first mixed material after mixing；By predetermined ratio by multi-vitamins, multiple
It closes after minerals are dissolved with 8-10 times of 45 DEG C of pure water in advance respectively and is uniformly mixed with the second mixed material, gained third mixture
Material squeezes into temporary storage tank III.
Step 3：Shearing and filtering：III third mixed material of temporary storage tank is poured into high speed by dosing pump or directly
After shearing tank, stirring after ten minutes, gets to standardization cylinder through duplex strainer and obtains the 4th mixed material.Standardization cylinder stirring is answered
Persistently it is kept stirring state, it is ensured that be uniformly mixed with material milk and ingredient is prevented to be layered.
Step 4：Homogeneous：4th mixed material is subjected to homogeneous, homogenizing temperature is 60-65 DEG C and pressure is 18-
20MPa obtains the 5th mixed material.
Step 5：Sterilization：5th mixed material is sterilized, sterilization temperature sterilizes 20-25 under conditions of being 89 ± 2 DEG C
Second.
Step 6：Concentration：The 5th mixed material after sterilization is concentrated into 20 ° of B é, obtains the 6th mixed material.
Step 7：Spray drying：It is spray-dried the 6th mixed material to obtain the 7th mixed material.
Step 8：Bean jelly：7th mixed material is cooled down into room temperature through fluidized bed.
Step 9：Mixing：By mixed in predetermined ratio addition phosphatidylserine, sialic acid, zeaxanthin three-dimensional mixer
It closes and uniformly obtains modulation milk powder.
The modulation milk powder of the present embodiment can also be packed accordingly according to actual needs, specifically using:Vacuum
Nitrogen charging or nitrogen mixing carbon dioxide carry out controlled atmospheric packing, final packaging product are obtained, marked as MKP-2.
Embodiment 3:
A kind of modulation milk powder improving memory, its raw material includes following components by weight percentage:Raw milk powder：
48 parts, skimmed milk powder：18 parts, bovine whey powder:15 parts, lactose：9.84 parts, corn oil：3 parts, hydrolysis yolk powder：1 part, yeast
Beta glucan：1.8 parts, Chinese yam：0.1 part, semen ziziphi spinosae：0.3 part, arillus longan：0.2 part, fructus alpiniae oxyphyllae：0.1 part, fish oil extract：
0.88 part, composite mineral matter：1.5 parts, multi-vitamins：0.06 part, phosphatidylserine：0.2 part, sialic acid：0.016 part,
Zeaxanthin：0.004 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：70%, acetic acid is tieed up
Raw element A：0.67%, Vitamin D3：0.011%, dl- ɑ-D-α-tocopherol acetate：29.319%.
The composite mineral matter is formed by following components and weight percent mixture:Calcium carbonate：86%, ferrous sulfate：
1.4%, zinc sulfate：0.596%, magnesium sulfate：12%, sodium selenite：0.04%.
A kind of modulation milk powder for improving memory of the present embodiment is made of dry mixing process, specifically includes following steps:
Step A：The preparation of integration of drinking and medicinal herbs object：Using pulverizer to the Chinese yam of predetermined ratio, semen ziziphi spinosae, arillus longan, fructus alpiniae oxyphyllae
It is crushed, the raw material of crushing is placed in container, 3-5 times of the 60-80% ethyl alcohol that weight is raw material weight is added, is soaked
Bubble extracts 2 times, merges alcohol extract and is concentrated into no alcohol taste；After material residue flings to ethyl alcohol, 6-8 times that weight is raw material weight is added
Water impregnated, decoction 30-60min carried out to soak, filtering removal raw material leaves and takes decoction liquor；Alcohol after merging concentration
Extract and decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder is finally prepared with 60-80 mesh point.
Step B：Level-one is dry-mixed, and the full-fat cow milk of predetermined ratio, hydrolysis yolk powder, integration of drinking and medicinal herbs object, fish oil are extracted
Object, yeast beta-dextran, phosphatidylserine, zeaxanthin, sialic acid, multi-vitamins, composite mineral matter are put into three-dimensional mixed
It is uniformly mixed in conjunction machine and obtains first material, by first material through two-phase transportation into high-speed mixer.
Step C：Second level is dry-mixed, by predetermined ratio by skimmed milk powder, bovine whey powder, glucose syrup solids, through what is embedded
Corn oil powder (is made using being spray-dried after bovine whey powder mixture in part in the corn oil and formula of predetermined ratio in formula
At), it puts into high-speed mixer and is uniformly mixed with first material to get modulation milk powder of the invention.
This modulation milk powder carries out controlled atmospheric packing using vacuum nitrogen or carbon dioxide, obtains final packaging product, label
For MKP-3；
The experimental result of product is shown in Table 1 respectively after the present embodiment 1,2,3 is packed
Table 1
Comparative example 1：(being free of fish oil extract)
Including following components:Raw milk powder：42.5 parts, skimmed milk powder：20 parts, bovine whey powder：18.9 parts, glucose
Starch solid：12 parts, corn oil：3 parts, hydrolysis yolk powder：0.7 part, inulin：1 part, walnut kernel：0.1 part, jujube：0.3 part, longan
Meat：0.1 part, fructus alpiniae oxyphyllae：0.2 part, composite mineral matter：1 part, multi-vitamins：0.1 part, phosphatidylserine：0.04 part, saliva
Liquid acid：0.055 part, zeaxanthin：0.005 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：80%, acetic acid is tieed up
Raw element A：0.4%, Vitamin D3：0.01%, dl- ɑ-D-α-tocopherol acetate：19.59%.
The composite mineral matter is formed by following components and weight percent mixture:Calcium carbonate：81.396%, sulfuric acid is sub-
Iron：1.8%, zinc sulfate：0.8%, magnesium sulfate：16%, sodium selenite：0.004%.
Comparative example 2：(being free of integration of drinking and medicinal herbs)
Including following components:Raw milk powder：42.5 parts, skimmed milk powder：20 parts, bovine whey powder：18.3 parts, glucose
Starch solid：12 parts, corn oil：3 parts, hydrolysis yolk powder：0.7 part, fish oil extract：1.3 parts, inulin：1 part, composite mineral matter：
1 part, multi-vitamins：0.1 part, phosphatidylserine：0.04 part, sialic acid：0.055 part, zeaxanthin：0.005 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：80%, acetic acid is tieed up
Raw element A：0.4%, Vitamin D3：0.01%, dl- ɑ-D-α-tocopherol acetate：19.59%.
It is described compound to be formed by following components and weight percent mixture:Calcium carbonate：81.396%, ferrous sulfate：
1.8%, zinc sulfate：0.8%, magnesium sulfate：16%, sodium selenite：0.004%.
Comparative example 3：(being free of zeaxanthin)
Including following components:Raw milk powder：42.5 parts, skimmed milk powder：20 parts, bovine whey powder：17.605 part, grape
Syrup solid：12 parts, corn oil：3 parts, hydrolysis yolk powder：0.7 part, fish oil extract：1.3 parts, inulin：1 part, walnut kernel：
0.1 part, jujube：0.3 part, arillus longan：0.1 part, fructus alpiniae oxyphyllae:0.2 part, composite mineral matter:1 part, multi-vitamins:0.1 part, phosphorus
Acyl serine:0.04 part, sialic acid:0.055 part.
The multi-vitamins are formed by following components and weight percent mixture:L-AA sodium：80%, acetic acid is tieed up
Raw element A：0.4%, Vitamin D3：0.01%, dl- ɑ-D-α-tocopherol acetate：19.59%.
The composite mineral matter is formed by following components and weight percent mixture:Calcium carbonate：81.396%, sulfuric acid is sub-
Iron：1.8%, zinc sulfate：0.8%, magnesium sulfate：16%, sodium selenite：0.04%.
The above comparative example preparation method is the same with the preparation method of embodiment.
The experimental result of product is shown in Table 2 respectively after comparative example 1,2,3 of the present invention is packed
Table 2
Clinical test-meal test：Following clinical test-meal test describes a kind of modulation milk powder of improvement memory of the invention
Improve the effect for the aspect remembered to person in middle and old age are changed.
It collects the healthy person in middle and old age of 350 mild memories declines and carries out clinical test-meal test, the age is 50-70 one full year of life；By
Try object：Subject did not received similar test, did not took article related with tested function in a short time.Before taking given the test agent
After carrying out the test of first time memory quotient to subject, subject's double-blind study is randomly divided into test-meal group, comparative example group by memory quotient
And control group, as far as possible consideration educational level, age etc., carry out harmonious inspection.It is randomly divided into test group 1, test group 2, examination
Group 3, control group 1, control group 2, control group 3 and blank control group are tested, every group each 50, the diet of blank control group is usual with it
Diet is the same, test group 1, test group 2, test group 3, control group 1, control group 2, control group 3 diet and its usual diet one
Sample is additionally respectively corresponded using the embodiment of the present invention 1 (MKP-1), embodiment 2 (MKP-2), embodiment 3 (MKP-3), comparative example
1, modulation prescription emulsifiable powder prepared by comparative example 2, comparative example 3 carries out intervention test-meal, and 1 day twice, and each group is in early, evening each edible 25
Gram improvement memory modulation milk powder, the time be 45 days.Clinical test-meal result table 3.
Table 3：The case where test-meal group 1, test-meal group 2, test-meal group 3, comparative example 1, comparative example 2, comparative example 3 and blank control group
Contrast table
Table 3
Note:*：Do not have otherness, * * between 0.05 two groups of P >：There is otherness, * * * between 0.05 two groups of P ﹤：0.01 liang of P ﹤
Group difference is significant.
Conclusion：From table 3 it can be seen that test group 1 (MKP-1), test group 2 (MKP-1), test group 3 (MKP-3) are clinical
Test-meal test result is substantially better than the blank control group of normal diet.It is provided by the invention eating compared with blank control group
After the modulation milk powder for improving memory, direction memory, associative learning, image is freed recall, meaningless image is re-recognized and portrait spy
Point connection recalls obvious equal memory index with there were significant differences before edible, to prove the tune provided by the invention for improving memory
Milk powder processed is to the effect of being significantly improved of mid-aged population memory.From the above it can also be seen that test group 1 (MKP-1) is clinical
Test-meal test result is superior to the edible comparative example 1 without fish oil extract, the comparative example 2 without integration of drinking and medicinal herbs and without corn
Control group 1, control group 2 and the control group 3 that yellow confrontation ratio 3 is formulated, and edible comparative example 1, comparative example 2, comparative example 3 are formulated
Control group 1, control group 2 and the clinical test-meal test result of control group 3 are significantly better than the blank control group of normal diet.It is possible thereby to
Find out, fish oil extract, integration of drinking and medicinal herbs and zeaxanthin all play critically important effect in entire formula.It is provided by the invention
Improve the modulation milk powder of memory by the synergistic effect between each component, the effect of being greatly improved remembered to mid-aged population,
Various improvement memory nutritional ingredients play respective function in vivo, and mutually collaboration is mutually promoted simultaneously, effective supply brain centres mind
Nutrition through system improves information transmission speed, enhances brain memory ability, improves brain function comprehensively.Modulation of the invention
It is languisher edible that milk powder is applicable to all age group memory, to the effect of being significantly improved of all age group crowd's memory,
Have the function of alleviating eye visual fatigue simultaneously, maintain skeleton density.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field
For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair
Change, equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.
Claims (9)
1. a kind of modulation milk powder for improving memory, which is characterized in that including following components:40-50 parts of whole-fat milk powder or comprising
Dry matter is equal to 17-25 parts equal to the full-cream lotion of 40-50 parts of whole-fat milk powder weight, skimmed milk powder 17-25 or comprising dry matter
15-23 parts of separated milk, the whey powder of skimmed milk powder weight, glucose syrup solids or 5-15 parts of lactose, 2-5 parts of vegetable oil, fish
0.2-3 parts of oil extract, hydrolysis yolk powder 0.1-1 parts, 0.01-2 parts of integration of drinking and medicinal herbs object, 0.01-3 parts of dietary fiber, grandidierite
0.2-2 parts of substance, 0.01-0.15 parts of multi-vitamins, 0.01-0.5 parts of sialic acid, 0.025-0.6 parts of phosphatidylserine, jade
Cream-coloured matter 0.002-0.008 parts.
2. a kind of modulation milk powder for improving memory according to claim 1, which is characterized in that the whole-fat milk powder is complete
Fat liquor, skimmed milk powder or separated milk and whey powder are made of milk or goat milk；Wherein, dry in the whole-fat milk powder
Matter content is 97%, and dry matter content is 11.7% in full-cream lotion；Dry matter content is 96% in the skimmed milk powder, degreasing
Dry matter content is 11.7% in lotion.
3. a kind of modulation milk powder for improving memory according to claim 1, which is characterized in that the vegetable oil is corn
One or more of oil, rapeseed oil, sunflower oil and coconut oil.
4. a kind of modulation milk powder for improving memory according to claim 1, which is characterized in that the fish oil extract is
Marine fish is heated to boil, squeezes, being centrifuged, purifying, decolourizing, deodorization and manufactured oily liquids or powder product, the ocean
Fish includes one or more of salmon, sardine and tuna.
5. a kind of modulation milk powder for improving memory according to claim 1, which is characterized in that the dietary fiber is low
One of Fructooligosaccharides, inulin, yeast beta-dextran or avenabeta glucosan are several.
6. a kind of modulation milk powder for improving memory according to claim 1, which is characterized in that the integration of drinking and medicinal herbs object is
One of rhizoma polygonati, Chinese yam, fructus alpiniae oxyphyllae, Poria cocos, jujube, semen ziziphi spinosae, arillus longan, fructus lycii, walnut kernel are several manufactured
Powder product.
7. a kind of preparation method of modulation milk powder for improving memory according to claim 1-6, feature exist
In preparation method is dry and wet combination process or dry mixing process.
8. a kind of preparation method of modulation milk powder for improving memory according to claim 7, which is characterized in that described dry
Wet combination process specifically includes following steps：
Step 1：The preparation of integration of drinking and medicinal herbs object：It is crushed, will be crushed using integration of drinking and medicinal herbs substance of the pulverizer to predetermined ratio
Raw material be placed in container, be added ethyl alcohol, impregnated, extracted, merge alcohol extract simultaneously be concentrated into no alcohol taste；Material residue flings to ethyl alcohol
Afterwards, add water to be impregnated, soak is decocted, filtering removal raw material leaves and takes decoction liquor；Merge concentration after alcohol extract and
Decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder product is finally prepared with 60-80 mesh point；
Step 2：Ingredient：Whole-fat milk powder, skimmed milk powder, whey powder, glucose syrup solids or lactose, medicine are eaten by predetermined ratio
It is added in 3-4 times 40-50 DEG C of weight of pure water after homologue, dietary fiber and hydrolysis yolk powder mixing, or by predetermined ratio
Whey powder, glucose syrup solids or lactose, integration of drinking and medicinal herbs object, dietary fiber and hydrolysis yolk powder are mixed and are added directly by example
In 40-50 DEG C of full-cream lotion and separated milk, resulting first mixed material squeezes into temporary storage tank I after being stirred uniformly；It takes pre-
The fish oil extract of certainty ratio is added in predetermined ratio vegetable oil uniformly mixed and the first mixed material gained after mixing
Second mixed material squeezes into temporary storage tank II；Multi-vitamins, composite mineral matter are used 10 times 40 DEG C~50 respectively by predetermined ratio
DEG C pure water is uniformly mixed after dissolving in advance with the second mixed material, and gained third mixed material squeezes into temporary storage tank III；
Step 3：Shearing and filtering：III third mixed material of temporary storage tank is poured into high speed shear by dosing pump or directly
After tank, stirring after ten minutes, gets to standardization cylinder through duplex strainer and obtains the 4th mixed material；
Step 4：Homogeneous：4th mixed material progress homogeneous is obtained into the 5th mixed material；
Step 5：Sterilization：5th mixed material is sterilized；
Step 6：Concentration：The 5th mixed material after sterilization is concentrated into 20-24 ° of B é, obtains the 6th mixed material；
Step 7：Spray drying：It is spray-dried the 6th mixed material to obtain the 7th mixed material；
Step 8：Bean jelly：7th mixed material is cooled down into room temperature through fluidized bed, water content is 2.5-4.0% in material；
Step 9：Mixing：It is mixed in three-dimensional mixer by predetermined ratio addition phosphatidylserine, zeaxanthin and sialic acid
Uniformly obtain modulation milk powder.
9. a kind of preparation method of modulation milk powder for improving memory according to claim 7, which is characterized in that described dry
Mixed technique specifically includes following steps：
Step A：The preparation of integration of drinking and medicinal herbs object：It is crushed, will be crushed using integration of drinking and medicinal herbs substance of the pulverizer to predetermined ratio
Raw material be placed in container, be added ethyl alcohol, impregnated, extracted, merge alcohol extract simultaneously be concentrated into no alcohol taste；Material residue flings to ethyl alcohol
Afterwards, add water to be impregnated, soak is decocted, filtering removal raw material leaves and takes decoction liquor；Merge concentration after alcohol extract and
Decoction liquor, and it is spray-dried, integration of drinking and medicinal herbs object powder product is finally prepared with 60-80 mesh point；
Step B：Level-one is dry-mixed, by the whole-fat milk powder of predetermined ratio, integration of drinking and medicinal herbs object, fish oil extract, hydrolysis yolk powder, diet
Fiber, phosphatidylserine, sialic acid, zeaxanthin, multi-vitamins, composite mineral matter are put into three-dimensional mixer and mix
It is even to obtain first material, by first material through two-phase transportation into high-speed mixer；
Step C：Second level is dry-mixed, by predetermined ratio by skimmed milk powder, whey powder, glucose syrup solids or lactose, the plant through embedding
Object oil powder puts into high-speed mixer and is uniformly mixed with first material to get modulation milk powder of the invention.
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