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CN108703770A - ventricular volume monitoring device and method - Google Patents

ventricular volume monitoring device and method Download PDF

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CN108703770A
CN108703770A CN201810307765.8A CN201810307765A CN108703770A CN 108703770 A CN108703770 A CN 108703770A CN 201810307765 A CN201810307765 A CN 201810307765A CN 108703770 A CN108703770 A CN 108703770A
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CN108703770B (en
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曹悦
曹阳
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Cao Yang
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Wisdom Valley Medical Technology (guangzhou) Co Ltd
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    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data

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Abstract

本申请涉及一种心室容积监测设备和方法,包括图像采集模块和处理器,图像采集模块与处理器连接,图像采集模块获取待监测对象的超声成像视频,处理器识别单个心动周期内超声成像视频的波动区域,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,并基于腔体面积变化信息得到待监测对象的心室容积变化信息。这样无需借助于心导管技术,不仅可以实现无创获取心室容积变化数据,还可以实现在不中断监测的情况下获得即时的心室容积变化数据,从而实现通过超声图像分析获得连续、无创的实时心室容积。

The application relates to a ventricular volume monitoring device and method, including an image acquisition module and a processor, the image acquisition module is connected to the processor, the image acquisition module acquires the ultrasonic imaging video of the object to be monitored, and the processor identifies the ultrasonic imaging video in a single cardiac cycle Obtain the total gray value of the fluctuation area, obtain the cavity area change information of the object to be monitored according to the total gray value of the fluctuation area, and obtain the ventricular volume change information of the object to be monitored based on the cavity area change information. In this way, without the use of cardiac catheter technology, not only non-invasive acquisition of ventricular volume change data can be achieved, but also real-time ventricular volume change data can be obtained without interrupting monitoring, so that continuous, non-invasive real-time ventricular volume can be obtained through ultrasound image analysis .

Description

心室容积监测设备和方法Ventricular volume monitoring device and method

技术领域technical field

本申请涉及生物医学工程技术领域,特别是涉及一种心室容积监测设备和方法。The present application relates to the technical field of biomedical engineering, in particular to a ventricular volume monitoring device and method.

背景技术Background technique

心脑血管血管疾病已成为危害人类健康的重要原因,心脏功能的测定不仅可以用于心血管疾病早期诊断、辅助诊断,还可以用于麻醉、患者监护等,对选拔运动员、海军、空军等体质要求较高的人员具有重要指导意义;同时,在评定心血管手术及药物效果和运动锻炼效果等方面也可提供客观指标。此外,心脏功能的测定对于发现一些疾病患者的亚临床性心肌损害和一些药物的负性肌力副作用方面也有重要意义。Cardiovascular and cerebrovascular diseases have become an important cause of harm to human health. The determination of cardiac function can not only be used for early diagnosis and auxiliary diagnosis of cardiovascular diseases, but also for anesthesia and patient monitoring. It has important guiding significance for those with higher requirements; at the same time, it can also provide objective indicators in evaluating the effects of cardiovascular surgery and drugs and exercise effects. In addition, the determination of cardiac function is also of great significance in the discovery of subclinical myocardial damage in patients with some diseases and the negative inotropic side effects of some drugs.

传统的心脏功能的测定方法主要是借助于心导管技术,如冠状动脉造影术。但冠状动脉造影术有一定的死亡率和并发症,比如心肌梗死、血管或心脏穿破或恶性心律失常等。因此,传统的心脏功能测定方法其操作过程中会对心脏造成创伤,存在创伤高风险的问题。The traditional method of measuring cardiac function is mainly by means of cardiac catheterization techniques, such as coronary angiography. However, coronary angiography has certain mortality and complications, such as myocardial infarction, blood vessel or heart puncture, or malignant arrhythmia. Therefore, the operation of the traditional cardiac function measurement method will cause trauma to the heart, and there is a problem of high trauma risk.

发明内容Contents of the invention

基于此,有必要针对上述技术问题,提供一种能够降低创伤风险的心室容积监测设备和方法。Based on this, it is necessary to provide a ventricular volume monitoring device and method capable of reducing the risk of trauma in view of the above technical problems.

一种心室容积监测设备,包括图像采集模块和处理器,所述图像采集模块与所述处理器连接;A ventricular volume monitoring device, comprising an image acquisition module and a processor, the image acquisition module being connected to the processor;

所述图像采集模块获取待监测对象的超声成像视频;所述处理器识别单个心动周期内所述超声成像视频帧的波动区域,获取所述波动区域的灰度总值,根据所述波动区域的灰度总值得到所述待监测对象的腔体面积变化信息,并基于所述腔体面积变化信息得到所述待监测对象的心室容积变化信息。The image acquisition module acquires the ultrasound imaging video of the object to be monitored; the processor identifies the fluctuation area of the ultrasound imaging video frame in a single cardiac cycle, acquires the total gray value of the fluctuation area, and according to the fluctuation area of the fluctuation area The gray total value obtains the cavity area change information of the object to be monitored, and obtains the ventricular volume change information of the object to be monitored based on the cavity area change information.

在一个实施例中,所述处理器还用于获取所述波动区域的各灰度值以及像素总值,根据所述各灰度值得到所述波动区域的灰度总值;基于所述波动区域的像素总值不变,根据所述像素总值与所述波动区域的灰度总值,得到所述待监测对象的腔体面积变化信息。In one embodiment, the processor is further configured to obtain each grayscale value and the total pixel value of the fluctuating region, and obtain the total grayscale value of the fluctuating region according to the grayscale values; based on the fluctuation The total pixel value of the region remains unchanged, and the cavity area change information of the object to be monitored is obtained according to the total pixel value and the total gray value of the fluctuating region.

在一个实施例中,所述处理器还用于将所述像素总值与所述波动区域的灰度总值之差作为腔体面积变化值,获取单个心动周期内待监测对象的超声成像视频的帧数及对应的腔体面积变化值,构建所述帧数与所述腔体面积变化值之间的关系曲线。In one embodiment, the processor is further configured to use the difference between the total pixel value and the total gray value of the fluctuating region as the cavity area change value to obtain the ultrasonic imaging video of the object to be monitored within a single cardiac cycle The number of frames and the corresponding change value of the cavity area are used to construct a relationship curve between the number of frames and the change value of the cavity area.

在一个实施例中,所述处理器还用于对所述腔体面积变化信息进行滤波平滑处理,基于滤波平滑处理后的腔体面积变化信息得到所述待监测对象的心室容积变化信息。In one embodiment, the processor is further configured to filter and smooth the cavity area change information, and obtain the ventricular volume change information of the subject to be monitored based on the filtered and smoothed cavity area change information.

在一个实施例中,所述处理器还用于基于预设补偿函数,对所述心室容积变化信息进行校准。In one embodiment, the processor is further configured to calibrate the ventricular volume change information based on a preset compensation function.

在一个实施例中,所述处理器还用于当所述待监测对象的超声成像视频为彩色图像视频时,对所述彩色图像视频进行灰度处理,识别单个心动周期内灰度处理后的超声成像视频的波动区域。In one embodiment, the processor is further configured to, when the ultrasound imaging video of the object to be monitored is a color image video, perform grayscale processing on the color image video, and identify grayscale processed Fluctuating regions of an ultrasound imaging video.

在一个实施例中,所述设备还包括超声成像采集装置,所述超声成像采集装置与所述处理器连接。In one embodiment, the device further includes an ultrasonic imaging acquisition device connected to the processor.

在一个实施例中,所述设备还包括显示器,所述显示器与所述处理器连接。In one embodiment, the device further includes a display connected to the processor.

在一个实施例中,所述设备还包括记录仪,所述记录仪与所述处理器连接。In one embodiment, the device further includes a recorder connected to the processor.

一种心室容积监测方法,所述方法包括:A method for monitoring ventricular volume, said method comprising:

获取待监测对象的超声成像视频;Obtain the ultrasound imaging video of the object to be monitored;

识别单个心动周期内所述超声成像视频的波动区域;identifying regions of fluctuation in the ultrasound imaging video within a single cardiac cycle;

获取所述波动区域的灰度总值,根据所述波动区域的灰度总值得到所述待监测对象的腔体面积变化信息;Acquiring the total gray value of the fluctuating area, and obtaining the cavity area change information of the object to be monitored according to the total gray value of the fluctuating area;

基于所述待监测对象的腔体面积变化信息得到所述待监测对象的心室容积变化信息。The ventricular volume change information of the subject to be monitored is obtained based on the cavity area change information of the subject to be monitored.

上述心室容积监测设备和方法,包括图像采集模块和处理器,图像采集模块与处理器连接;图像采集模块获取待监测对象的超声成像视频,处理器识别单个心动周期内超声成像视频的波动区域,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,并基于腔体面积变化信息得到待监测对象的心室容积变化信息。通过对获取到的待监测对象的超声成像视频进行处理,识别单个心动周期内超声成像视频的波动区域,根据待监测对象的超声成像视频帧的波动区域的灰度总值,得到待监测对象的腔体面积变化信息,再基于腔体面积变化信息获得心室容积变化信息,这样无需借助于心导管技术,不仅可以实现无创获取心室容积变化数据,还可以实现在不中断监测的情况下获得即时的心室容积变化数据,从而实现通过超声图像分析获得连续、无创的实时心室容积。The above-mentioned ventricular volume monitoring device and method include an image acquisition module and a processor, the image acquisition module is connected to the processor; the image acquisition module acquires the ultrasound imaging video of the object to be monitored, and the processor identifies the fluctuation area of the ultrasound imaging video in a single cardiac cycle, The total gray value of the fluctuating area is acquired, the cavity area change information of the object to be monitored is obtained according to the total gray value of the fluctuating area, and the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information. By processing the acquired ultrasound imaging video of the object to be monitored, the fluctuation area of the ultrasound imaging video in a single cardiac cycle is identified, and the total gray value of the fluctuation area of the ultrasound imaging video frame of the object to be monitored is obtained to obtain the monitoring object. Cavity area change information, and then obtain ventricular volume change information based on the cavity area change information, so that without the use of cardiac catheterization technology, not only can non-invasive acquisition of ventricular volume change data, but also real-time monitoring can be obtained without interrupting monitoring The change data of ventricular volume can be obtained continuously and non-invasively in real time through ultrasound image analysis.

附图说明Description of drawings

图1为一个实施例中心室容积监测设备的结构框图;Fig. 1 is a structural block diagram of a central chamber volume monitoring device of an embodiment;

图2为一个实施例中波动区域的示意图;Fig. 2 is a schematic diagram of a fluctuation region in an embodiment;

图3为一个实施例超声图像的示意图;Fig. 3 is a schematic diagram of an embodiment of an ultrasonic image;

图4为一个实施例中一个心动周期内腔体横截面积变化曲线的示意图;Fig. 4 is a schematic diagram of the change curve of the cavity cross-sectional area in one cardiac cycle in one embodiment;

图5为一个实施例中锐化处理的流程示意图;Fig. 5 is a schematic flow chart of sharpening processing in an embodiment;

图6为一个实施例中心室容积监测方法的流程示意图。Fig. 6 is a schematic flowchart of a method for monitoring central chamber volume according to an embodiment.

具体实施方式Detailed ways

为了使本申请的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本申请进行进一步详细说明。应当理解,此处描述的具体实施例仅仅用以解释本申请,并不用于限定本申请。In order to make the purpose, technical solution and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present application, and are not intended to limit the present application.

在一个实施例中,如图1所示,提供了一种心室容积监测设备,包括图像采集模块100和处理器200,图像采集模块100与处理器200连接;图像采集模块100获取待监测对象的超声成像视频;处理器200识别单个心动周期内超声成像视频的波动区域,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,并基于腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, as shown in FIG. 1 , a ventricular volume monitoring device is provided, including an image acquisition module 100 and a processor 200, and the image acquisition module 100 is connected to the processor 200; the image acquisition module 100 acquires the Ultrasound imaging video; the processor 200 identifies the fluctuation area of the ultrasound imaging video in a single cardiac cycle, obtains the total gray value of the fluctuation area, and obtains the cavity area change information of the object to be monitored according to the total gray value of the fluctuation area, and based on the cavity The volume change information of the body area is obtained by obtaining the change information of the ventricular volume of the object to be monitored.

图像采集模块100获取待监测对象的超声成像视频,比如可以通过专用的图像采集芯片,完成对超声成像设备的超声成像视频的采集。待监测对象的超声成像视频具体可以是单个心动周期内待监测对象的超声成像视频。心动周期是指从一次心跳的起始到下一次心跳的起始,心血管系统所经历的过程。心脏舒张时内压降低,腔静脉血液回流入心;心脏收缩时内压升高,将血液泵到动脉;心脏每收缩和舒张一次构成一个心动周期。一个心动周期中首先是两心房收缩,其中右心房的收缩略先于左心房;心房开始舒张后两心室收缩,而左心室的收缩略先于右心室,在心室舒张的后期心房又开始收缩。如以成年人平均心率每分钟75次计,每一心动周期平均为0.8秒,其中心房收缩期平均为0.11秒,舒张期平均为0.69秒;心室收缩期平均为0.27秒,舒张期平均为0.53秒。The image acquisition module 100 acquires the ultrasonic imaging video of the object to be monitored. For example, the acquisition of the ultrasonic imaging video of the ultrasonic imaging device can be completed through a dedicated image acquisition chip. The ultrasound imaging video of the object to be monitored may specifically be an ultrasound imaging video of the object to be monitored within a single cardiac cycle. The cardiac cycle refers to the process experienced by the cardiovascular system from the start of one heartbeat to the start of the next heartbeat. During diastole, the internal pressure decreases, and blood from the vena cava returns to the heart; during systole, the internal pressure increases, and blood is pumped to the artery; each contraction and relaxation of the heart constitutes a cardiac cycle. In a cardiac cycle, the two atria contract first, and the contraction of the right atrium slightly precedes that of the left atrium; the two ventricles contract after the atrium begins to relax, and the contraction of the left ventricle slightly precedes the right ventricle, and the atrium begins to contract again in the late period of ventricular diastole. For example, based on the average adult heart rate of 75 beats per minute, each cardiac cycle averages 0.8 seconds, the average atrial systolic period is 0.11 seconds, and the average diastolic period is 0.69 seconds; the average ventricular systolic period is 0.27 seconds, and the average diastolic period is 0.8 seconds 0.53 seconds.

超声成像设备在医疗诊断中起着举足轻重的地位,其以快速、安全和实时等优点在医疗的诊断中发挥着巨大的作用,广泛应用于医疗诊断、术前计划、治疗、术后监测等各个环节中。超声成像设备的工作原理可以是阵列声场延时叠加成像,在这种方式中,通过对阵列的各个单元引入不同的延时,而后合成为一聚焦波束,以实现对声场各点的成像。Ultrasound imaging equipment plays a pivotal role in medical diagnosis. It plays a huge role in medical diagnosis with the advantages of fast, safe and real-time. It is widely used in medical diagnosis, preoperative planning, treatment, postoperative monitoring, etc. in the link. The working principle of the ultrasonic imaging equipment can be array sound field delay superposition imaging. In this way, different delays are introduced to each unit of the array, and then synthesized into a focused beam to realize imaging of each point of the sound field.

处理器200识别单个心动周期内超声成像视频的波动区域,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,并基于腔体面积变化信息得到待监测对象的心室容积变化信息。对待监测对象的超声成像视频进行处理,区分波动区域和稳定区域,比如可以根据采集到的超声成像视频的视频序列,分析各超声图像中各像素灰度值相对于时间的变化率。具体地,某像素灰度值在一个心动周期内灰度值的变化范围大于或等于预设值,则视为有效像素;若其变化范围小于预设值,则可视为其它组织区域或信号噪声波动。这样可以区分波动区域和稳定区域,缩小检测范围,排除周边区域的干扰,其中,不同设备在不同环境下图像质量存在区别,预设值一般在30-60之间。以稳定区域像素的平均灰度值变化来评估整个检测区域的灰度指数,按熵的大小将视频区域分为波动区域和稳定区域,以区分波动区域像素和稳定区域像素,以排除肌肉组织血管等对腔体面积识别的干扰。单个心动周期内的超声成像视频包括多个超声图像,像素值表示图像的大小,像素坐标表示地址,灰度值表示地址中的值。波动区域是指灰度值随心动波动的区域,在整个心动周期的视频,如图2所示,左下框内区域始终为白色(灰度值始终为250以上,且并无较大波动),此区域即被视为稳定区域;右上框内区域始终随心动过程反复黑白变化(灰度值从10-250之间反复较大波动),此区域被视为波动区域。依据上述规则,根据每个视频样本,最终识别出的波动区域将是一个不规则形状的固定选区,该区域内所有像素灰度值随心动变化做有规律的波动。根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,由于心脏跳动过程中,各腔室形状并无明显变化,所以心室体积与腔体面积存在比例关系,假定比例系数为k,就可以根据腔体面积变化信息,得到心室容积变化信息。The processor 200 identifies the fluctuation region of the ultrasound imaging video in a single cardiac cycle, obtains the total gray value of the fluctuation region, obtains the cavity area change information of the object to be monitored according to the total gray value of the fluctuation region, and based on the cavity area change information Obtain the change information of the ventricular volume of the object to be monitored. The ultrasonic imaging video of the object to be monitored is processed to distinguish the fluctuating area from the stable area. For example, the rate of change of the gray value of each pixel in each ultrasonic image relative to time can be analyzed according to the video sequence of the collected ultrasonic imaging video. Specifically, if the variation range of the gray value of a certain pixel within a cardiac cycle is greater than or equal to the preset value, it is regarded as a valid pixel; if its variation range is smaller than the preset value, it can be regarded as other tissue area or signal Noise fluctuations. In this way, the fluctuation area and the stable area can be distinguished, the detection range can be narrowed, and the interference of the surrounding area can be eliminated. Among them, the image quality of different devices is different in different environments, and the preset value is generally between 30-60. The gray index of the entire detection area is evaluated by the average gray value change of the pixels in the stable area, and the video area is divided into a fluctuating area and a stable area according to the size of the entropy to distinguish the fluctuating area pixels from the stable area pixels to exclude muscle tissue blood vessels and so on interfere with the identification of the cavity area. The ultrasound imaging video in a single cardiac cycle includes multiple ultrasound images, the pixel value represents the size of the image, the pixel coordinates represent the address, and the grayscale value represents the value in the address. The fluctuation area refers to the area where the gray value fluctuates with the heartbeat. In the video of the entire cardiac cycle, as shown in Figure 2, the area in the lower left frame is always white (the gray value is always above 250, and there is no large fluctuation). This area is regarded as a stable area; the area in the upper right box always changes black and white repeatedly with the cardiac process (the gray value fluctuates repeatedly from 10 to 250), and this area is regarded as a fluctuating area. According to the above rules, according to each video sample, the finally identified fluctuation area will be an irregularly shaped fixed selection area, and the gray value of all pixels in this area fluctuates regularly with the change of heartbeat. According to the total gray value of the fluctuation area, the change information of the cavity area of the object to be monitored is obtained. Since the shape of each cavity does not change significantly during the beating process of the heart, there is a proportional relationship between the volume of the ventricle and the area of the cavity, and the proportional coefficient is assumed to be k , the change information of the ventricular volume can be obtained according to the change information of the cavity area.

上述心室容积监测设备,包括图像采集模块和处理器,图像采集模块与处理器连接;图像采集模块获取待监测对象的超声成像视频,处理器识别单个心动周期内超声成像视频的波动区域,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,并基于腔体面积变化信息得到待监测对象的心室容积变化信息。通过对获取到的待监测对象的超声成像视频进行处理,识别单个心动周期内超声成像视频的波动区域,根据待监测对象的超声成像视频的波动区域的灰度总值,得到待监测对象的腔体面积变化信息,再基于腔体面积变化信息获得心室容积变化信息,这样无需借助于心导管技术,不仅可以实现无创获取心室容积变化数据,还可以实现在不中断监测的情况下获得即时的心室容积变化数据,从而实现通过超声图像分析获得连续、无创的实时心室容积。The above-mentioned ventricular volume monitoring device includes an image acquisition module and a processor, the image acquisition module is connected to the processor; the image acquisition module acquires the ultrasound imaging video of the object to be monitored, and the processor identifies the fluctuation area of the ultrasound imaging video in a single cardiac cycle, and acquires the fluctuation area According to the total gray value of the area, the cavity area change information of the object to be monitored is obtained according to the total gray value of the fluctuating area, and the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information. By processing the acquired ultrasound imaging video of the object to be monitored, the fluctuation area of the ultrasound imaging video in a single cardiac cycle is identified, and the cavity of the object to be monitored is obtained according to the total gray value of the fluctuation area of the ultrasound imaging video of the object to be monitored. Body area change information, and then based on the cavity area change information to obtain ventricular volume change information, so that without the use of cardiac catheterization technology, not only non-invasive acquisition of ventricular volume change data, but also real-time ventricular volume change information can be obtained without interrupting monitoring. Volume change data, so as to achieve continuous, non-invasive real-time ventricular volume through ultrasound image analysis.

在一个实施例中,处理器获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息,包括:获取波动区域的各灰度值以及像素总值,根据各灰度值得到波动区域的灰度总值;基于波动区域的像素总值不变,根据像素总值与波动区域的灰度总值,得到待监测对象的腔体面积变化信息。通过阴影检测可以分辨波动区域中的阴影区域,把波动区域中阴影区域与周边图像分离出来,即正确分割出阴影区域的轮廓。阴影是由于光源点照射到背景的光线受到了目标物的阻挡而形成的,但是场景中的光照强度并不会改变背景的表面纹理特征结构;由于阴影区域所获得的入射光线强度减弱,所以阴影区域的像素值会比该区域无阴影时的像素值要小。In one embodiment, the processor obtains the total gray value of the fluctuation area, and obtains the cavity area change information of the object to be monitored according to the total gray value of the fluctuation area, including: obtaining each gray value of the fluctuation area and the total pixel value , the total gray value of the fluctuating area is obtained according to each gray value; based on the fact that the total pixel value of the fluctuating area remains unchanged, the change information of the cavity area of the object to be monitored is obtained according to the total pixel value and the total gray value of the fluctuating area. Through the shadow detection, the shadow area in the fluctuation area can be distinguished, and the shadow area in the fluctuation area can be separated from the surrounding image, that is, the outline of the shadow area can be correctly segmented. The shadow is formed because the light irradiated by the light source point to the background is blocked by the target object, but the light intensity in the scene does not change the surface texture characteristic structure of the background; because the incident light intensity obtained by the shadow area is weakened, the shadow The pixel values of the area will be smaller than the pixel values of the area without shadow.

在一个实施例中,处理器根据像素总值与波动区域的灰度总值,得到待监测对象的腔体面积变化信息,包括:将像素总值与波动区域的灰度总值之差作为腔体面积变化值;获取单个心动周期内待监测对象的超声成像视频的帧数及对应的腔体面积变化值;构建帧数与腔体面积变化值之间的关系曲线。具体地,像素总值为255*n,n为总检测像素数,波动区域的灰度总值∑G等于波动区域各像素灰度值之和,腔体面积变化值为255*n-∑G。在一个实施例中,处理器还用于获取波动区域的各像素灰度值,根据波动区域的灰度总值不变和各像素灰度值,得到待监测对象的腔体面积变化信息。对于如图3所示的超声图像,图中所示扇形区域内均为灰度像素,灰度范围为0-255,0为黑色即腔体区域,255为白色即肌肉组织。对波动区域的所有像素灰度值求和,得到波动区域的灰度总值。波动区域内各像素灰度值分别为g1,g2……gn,则波动区域内灰度总值∑G=g1+g2+……+gn,其中n为波动区域内的像素数,g为像素灰度值,∑G为采集的视频帧的像素灰度总值。因总检测像素数n保持不变,所以腔体横截面积(黑色区域)变化值即为255*n-∑G。根据每帧图像上述变化值绘制拟合曲线,经过滤波平滑处理,剔除较大噪声波动后,可得如图4所示的一个心动周期内的腔体横截面积变化曲线。In one embodiment, the processor obtains the cavity area change information of the object to be monitored according to the total pixel value and the total gray value of the fluctuating area, including: taking the difference between the total pixel value and the total gray value of the fluctuating area as the cavity Body area change value; obtain the frame number of the ultrasound imaging video of the object to be monitored in a single cardiac cycle and the corresponding cavity area change value; construct a relationship curve between the frame number and the cavity area change value. Specifically, the total value of pixels is 255*n, n is the total number of detected pixels, the total gray value ∑G of the fluctuation area is equal to the sum of the gray values of each pixel in the fluctuation area, and the change value of the cavity area is 255*n-∑G . In one embodiment, the processor is further configured to obtain the gray value of each pixel in the fluctuating area, and obtain the change information of the cavity area of the object to be monitored according to the constant gray value of the fluctuating area and the gray value of each pixel. For the ultrasound image shown in Figure 3, the fan-shaped area shown in the figure is grayscale pixels, the grayscale range is 0-255, 0 is black, that is, the cavity area, and 255 is white, that is, muscle tissue. The gray value of all pixels in the fluctuating area is summed to obtain the total gray value of the fluctuating area. The gray value of each pixel in the fluctuating area is g1, g2...gn respectively, then the total gray value in the fluctuating area ∑G=g1+g2+...+gn, where n is the number of pixels in the fluctuating area, and g is the pixel gray ΣG is the total pixel gray value of the collected video frame. Since the total detection pixel number n remains unchanged, the change value of the cavity cross-sectional area (black area) is 255*n-ΣG. A fitting curve was drawn according to the above-mentioned change values of each frame of image, and after filtering and smoothing to remove large noise fluctuations, the change curve of the cavity cross-sectional area within one cardiac cycle was obtained as shown in Figure 4 .

在一个实施例中,通过专用图像采集芯片,实时自动完成对超声成像视频的图像采集和视频解码,并以变换编码方式,通过数据无光的方式解除输入信号之间的相关性。通过使用USM(Unsharp Mask,锐化算法)技术,增强图像高频部分内容,减弱低频内容,使图像视觉效果进一步锐化,识别准确度得到极大提升。锐化处理的流程如图5所示,具体的表达式为:y(n,m)=x(n,m)+λz(n,m),其中,x(n,m)为输入图像,y(n,m)为输出图像,而z(n,m)为校正信号,通过对x进行高通滤波获取。λ是用于控制增强效果的缩放因子。在USM算法中,z(n,m)可通过z(n,m)=4x(n,m)-x(n-1,m)-x(n+1,m)-x(n,m-1)-x(n,m+1)获取。In one embodiment, the image acquisition and video decoding of the ultrasonic imaging video are automatically completed in real time through a dedicated image acquisition chip, and the correlation between input signals is decoupled in a data-free manner by means of transform coding. By using USM (Unsharp Mask, sharpening algorithm) technology, the high-frequency content of the image is enhanced, and the low-frequency content is weakened, so that the visual effect of the image is further sharpened, and the recognition accuracy is greatly improved. The flow of the sharpening process is shown in Figure 5, and the specific expression is: y(n, m)=x(n, m)+λz(n, m), where x(n, m) is the input image, y(n,m) is the output image, and z(n,m) is the correction signal obtained by high-pass filtering x. λ is a scaling factor used to control the enhancement effect. In the USM algorithm, z(n, m) can be obtained by z(n, m)=4x(n, m)-x(n-1, m)-x(n+1, m)-x(n, m -1)-x(n, m+1) acquisition.

在一个实施例中,处理器基于腔体面积变化信息得到待监测对象的心室容积变化信息,包括:对腔体面积变化信息进行滤波平滑处理,基于滤波平滑处理后的腔体面积变化信息得到待监测对象的心室容积变化信息。经过滤波平滑处理,可以剔除较大的噪声波动。平滑滤波是低频增强的空间域滤波技术,它的目的有两类:一类是模糊;另一类是消除噪音。空间域的平滑滤波可以采用简单平均法进行,就是求邻近像元点的平均亮度值。邻域的大小与平滑的效果直接相关,邻域越大平滑的效果越好,但邻域过大,平滑会使边缘信息损失的越大,从而使输出的图像变得模糊,因此需合理选择邻域的大小。In one embodiment, the processor obtains the ventricular volume change information of the subject to be monitored based on the cavity area change information. Monitor the subject's ventricular volume change information. After filtering and smoothing, larger noise fluctuations can be eliminated. Smoothing filter is a low-frequency enhanced spatial domain filtering technology, and its purpose has two types: one is blurring; the other is noise removal. The smoothing filter in the spatial domain can be carried out by simple average method, which is to calculate the average brightness value of adjacent pixel points. The size of the neighborhood is directly related to the smoothing effect. The larger the neighborhood, the better the smoothing effect, but if the neighborhood is too large, the smoothing will cause a greater loss of edge information, thus making the output image blurry, so it is necessary to choose a reasonable The size of the neighborhood.

在一个实施例中,处理器还用于基于预设补偿函数,对心室容积变化信息进行校准。心室容积与心室横截面积存在比例关系,假设比例系数为k,心室容积变化值△V的公式为:△V=k*(255*n-∑G)。考虑到不同病例心脏跳动特征不同,如婴幼儿、中老年、脂肪含量、心脏病变等影像因素,为优化校准检测结果,特殊病例可设置比例补偿函数f(e),那么△V=k*f(e)*(255*n-∑G),其中k为正常心室面积体积比例系数,f(e)为特殊补偿比例函数,△V为最终心室体积变化值。In one embodiment, the processor is further configured to calibrate the information on the change of the volume of the ventricle based on a preset compensation function. There is a proportional relationship between ventricular volume and ventricular cross-sectional area. Assuming that the proportional coefficient is k, the formula for the ventricular volume change value △V is: △V=k*(255*n-∑G). Considering the different characteristics of heart beating in different cases, such as imaging factors such as infants, middle-aged and elderly people, fat content, heart disease, etc., in order to optimize and calibrate the detection results, a proportional compensation function f(e) can be set for special cases, then △V=k*f (e)*(255*n-∑G), where k is the normal ventricular area-to-volume ratio coefficient, f(e) is the special compensation ratio function, and △V is the final ventricular volume change value.

在一个实施例中,处理器识别单个心动周期内超声成像视频的波动区域之前还包括:当待监测对象的超声成像视频为彩色图像视频时,对彩色图像视频进行灰度处理;处理器识别单个心动周期内超声成像视频的波动区域,包括:处理器识别单个心动周期内灰度处理后的超声成像视频的波动区域。当待监测对象的超声成像视频为彩色图像视频时,将饱和度高的像素的亮度的饱和度值降为最低,以灰度模式进行后续分析处理,以排除干扰,而最终以彩色模式显示与用户界面。比如,可以将RGB值差异超过5的像素的RGB值降为R-0,G-0,B-0后实施上述运算,以排除干扰。RGB色彩模式是工业界的一种颜色标准,通过对红(R)、绿(G)、蓝(B)三个颜色通道的变化以及它们相互之间的叠加来得到各式各样的颜色,RGB即代表红、绿、蓝三个通道的颜色。非必要的,当检测区域与背景连通时,最终目标区域的选择要限制在扇形区域内,不能选到黑色背景。In one embodiment, before the processor identifies the fluctuation region of the ultrasound imaging video in a single cardiac cycle, it further includes: when the ultrasound imaging video of the object to be monitored is a color image video, performing grayscale processing on the color image video; The fluctuation area of the ultrasound imaging video in a cardiac cycle includes: the processor identifies the fluctuation area of the gray-scale processed ultrasound imaging video in a single cardiac cycle. When the ultrasonic imaging video of the object to be monitored is a color image video, the saturation value of the brightness of the pixel with high saturation is reduced to the minimum, and the subsequent analysis and processing are performed in grayscale mode to eliminate interference, and finally displayed in color mode. User Interface. For example, the RGB values of pixels whose RGB values differ by more than 5 can be reduced to R-0, G-0, and B-0, and then the above operation can be performed to eliminate interference. The RGB color mode is a color standard in the industry. A variety of colors are obtained by changing the three color channels of red (R), green (G), and blue (B) and superimposing them with each other. RGB stands for the colors of the three channels of red, green and blue. Optionally, when the detection area is connected to the background, the selection of the final target area should be limited to the fan-shaped area, and the black background cannot be selected.

在一个实施例中,设备还包括超声成像采集装置,超声成像采集装置与处理器连接。超声成像采集装置可以包括超声探头,通过超声探头获取待监测对象的心脏超声图像。In one embodiment, the device further includes an ultrasonic imaging acquisition device connected to the processor. The ultrasonic imaging acquisition device may include an ultrasonic probe, and acquires an ultrasonic cardiac image of the subject to be monitored through the ultrasonic probe.

在一个实施例中,设备还包括显示器,显示器与处理器连接。显示器可以是液晶显示屏,可以显示待监测对象的腔体面积变化信息、心室容积变化信息等。In one embodiment, the device further includes a display connected to the processor. The display can be a liquid crystal display, which can display information about changes in cavity area and ventricular volume of the object to be monitored.

在一个实施例中,设备还包括记录仪,记录仪与处理器连接,记录仪可以记录处理器生成的各种拟合曲线。记录仪是将一个或多个变量随时间或另一变量变化的过程转换为可识别和读取的信号的仪器。记录仪是以CPU(Central Processing Unit,中央处理器)为核心,并辅以大规模集成电路、大容量FLASH(闪存)存储、信号智能调理、总线以及高分辨率图形液晶显示器的新型智能化无纸记录仪表。采用长寿命背光160×128单色液晶显示屏,支持4/8/16通道模拟量通用输入或2/4/8通道模拟输出与12通道报警输出,设定数据与记录数据具掉电保护功能,具有体积小、通道数多、功耗低、精度高、通用性强、运行稳定、可靠性高等特点。它能保存所记录的信号变化以便分析处理,记录仪能自动记录周期性或非周期性多路信号的慢变化过程和瞬态电平变化过程。In one embodiment, the device further includes a recorder connected to the processor, and the recorder can record various fitting curves generated by the processor. A recorder is an instrument that converts the process of one or more variables changing over time or another variable into a signal that can be recognized and read. The recorder takes the CPU (Central Processing Unit) as the core, supplemented by large-scale integrated circuits, large-capacity FLASH (flash memory) storage, signal intelligent conditioning, bus and a new type of intelligent wireless display with high-resolution graphics. Paper record meter. Adopt long-life backlight 160×128 monochrome LCD display, support 4/8/16 channel analog universal input or 2/4/8 channel analog output and 12 channel alarm output, set data and record data with power-down protection function , has the characteristics of small size, large number of channels, low power consumption, high precision, strong versatility, stable operation, and high reliability. It can save the recorded signal changes for analysis and processing, and the recorder can automatically record the slow change process and transient level change process of periodic or non-periodic multi-channel signals.

在一个实施例中,如图6所示,一种心室容积监测方法,包括:步骤602,获取待监测对象的超声成像视频;步骤604,识别单个心动周期内超声成像视频的波动区域;步骤606,获取波动区域的灰度总值,根据波动区域的灰度总值得到待监测对象的腔体面积变化信息;步骤608,基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, as shown in FIG. 6 , a method for monitoring ventricular volume includes: step 602, acquiring an ultrasound imaging video of an object to be monitored; step 604, identifying the fluctuation region of the ultrasound imaging video within a single cardiac cycle; step 606 , obtain the total gray value of the fluctuating area, and obtain the cavity area change information of the object to be monitored according to the total gray value of the fluctuating area; step 608, obtain the ventricular volume change of the object to be monitored based on the cavity area change information of the object to be monitored information.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;识别单个心动周期内超声成像视频的波动区域;获取波动区域的各灰度值以及像素总值,根据各灰度值得到波动区域的灰度总值;基于波动区域的像素总值不变,根据像素总值与波动区域的灰度总值,得到待监测对象的腔体面积变化信息;基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, the method for monitoring ventricular volume includes: acquiring an ultrasound imaging video of an object to be monitored; identifying the fluctuation area of the ultrasound imaging video in a single cardiac cycle; acquiring each gray value of the fluctuation area and the total pixel value, according to each gray scale The total value of the gray scale of the fluctuation area is obtained; the total value of the pixel based on the fluctuation area remains unchanged, and the change information of the cavity area of the object to be monitored is obtained according to the total value of the pixel and the total value of the gray scale of the fluctuation area; based on the cavity area of the object to be monitored The volume change information of the body area is obtained by obtaining the change information of the ventricular volume of the object to be monitored.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;识别单个心动周期内超声成像视频的波动区域;获取波动区域的各灰度值,根据各灰度值得到波动区域的灰度总值;基于波动区域的像素总值不变,根据像素总值与波动区域的灰度总值,得到待监测对象的腔体面积变化信息;基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息;其中,根据像素总值与波动区域的灰度总值,得到待监测对象的腔体面积变化信息,包括:将像素总值与波动区域的灰度总值之差作为腔体面积变化值;获取单个心动周期内待监测对象的超声成像视频的帧数及对应的腔体面积变化值;构建帧数与腔体面积变化值之间的关系曲线。In one embodiment, the method for monitoring ventricular volume includes: acquiring an ultrasound imaging video of an object to be monitored; identifying the fluctuation area of the ultrasound imaging video within a single cardiac cycle; acquiring each gray value of the fluctuation area, and obtaining the fluctuation area according to each gray value The total value of the gray scale; based on the total value of the pixel in the fluctuation area remains unchanged, according to the total value of the pixel and the total value of the gray scale in the fluctuation area, the change information of the cavity area of the object to be monitored is obtained; based on the change information of the cavity area of the object to be monitored Obtain the ventricular volume change information of the object to be monitored; wherein, according to the total pixel value and the total gray value of the fluctuation area, the cavity area change information of the object to be monitored is obtained, including: combining the total pixel value and the total gray value of the fluctuation area The difference is used as the change value of the cavity area; the number of frames of the ultrasound imaging video of the object to be monitored in a single cardiac cycle and the corresponding change value of the cavity area are obtained; and the relationship curve between the number of frames and the change value of the cavity area is constructed.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;对单个心动周期内的超声成像视频进行锐化处理,识别锐化处理后的超声成像视频的波动区域;获取波动区域的灰度总值;根据波动区域的灰度总值得到待监测对象的腔体面积变化信息;基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, the method for monitoring ventricular volume includes: acquiring an ultrasound imaging video of an object to be monitored; performing sharpening processing on the ultrasound imaging video within a single cardiac cycle, and identifying the fluctuation area of the sharpened ultrasound imaging video; acquiring the fluctuation The total gray value of the area; the cavity area change information of the object to be monitored is obtained according to the total gray value of the fluctuation area; the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information of the object to be monitored.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;识别单个心动周期内超声成像视频的波动区域;获取波动区域的灰度总值;根据波动区域的灰度总值得到待监测对象的腔体面积变化信息;对腔体面积变化信息进行滤波平滑处理,基于滤波平滑处理后的腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, the method for monitoring ventricular volume includes: acquiring an ultrasound imaging video of an object to be monitored; identifying the fluctuation area of the ultrasound imaging video within a single cardiac cycle; acquiring the total gray value of the fluctuation area; according to the total gray value of the fluctuation area The cavity area change information of the object to be monitored is obtained; the cavity area change information is filtered and smoothed, and the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information after the filtering and smoothing process.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;识别单个心动周期内超声成像视频的波动区域;获取波动区域的灰度总值;根据波动区域的灰度总值得到待监测对象的腔体面积变化信息;基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息;基于预设补偿函数,对心室容积变化信息进行校准。In one embodiment, the method for monitoring ventricular volume includes: acquiring an ultrasound imaging video of an object to be monitored; identifying the fluctuation area of the ultrasound imaging video within a single cardiac cycle; acquiring the total gray value of the fluctuation area; according to the total gray value of the fluctuation area The cavity area change information of the object to be monitored is obtained; the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information of the object to be monitored; and the ventricular volume change information is calibrated based on a preset compensation function.

在一个实施例中,心室容积监测方法包括:获取待监测对象的超声成像视频;当待监测对象的超声成像视频帧为彩色图像视频时,对彩色图像视频进行灰度处理;识别单个心动周期内灰度处理后的超声成像视频的波动区域;获取波动区域的灰度总值;根据波动区域的灰度总值得到待监测对象的腔体面积变化信息;基于待监测对象的腔体面积变化信息得到待监测对象的心室容积变化信息。In one embodiment, the method for monitoring ventricular volume includes: acquiring the ultrasound imaging video of the object to be monitored; when the ultrasound imaging video frame of the object to be monitored is a color image video, performing grayscale processing on the color image video; identifying The fluctuation area of the ultrasonic imaging video after grayscale processing; obtain the total gray value of the fluctuation area; obtain the cavity area change information of the object to be monitored according to the total gray value of the fluctuation area; based on the cavity area change information of the object to be monitored Obtain the change information of the ventricular volume of the object to be monitored.

关于心室容积监测方法的具体限定可以参见上文中对于心室容积监测设备的限定,在此不再赘述。For specific limitations on the ventricular volume monitoring method, refer to the above-mentioned limitations on the ventricular volume monitoring device, which will not be repeated here.

以上实施例的各技术特征可以进行任意的组合,为使描述简洁,未对上述实施例中的各个技术特征所有可能的组合都进行描述,然而,只要这些技术特征的组合不存在矛盾,都应当认为是本说明书记载的范围。The technical features of the above embodiments can be combined arbitrarily. To make the description concise, all possible combinations of the technical features in the above embodiments are not described. However, as long as there is no contradiction in the combination of these technical features, they should be It is considered to be within the range described in this specification.

以上所述实施例仅表达了本申请的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本申请构思的前提下,还可以做出若干变形和改进,这些都属于本申请的保护范围。因此,本申请专利的保护范围应以所附权利要求为准。The above-mentioned embodiments only represent several implementation modes of the present application, and the description thereof is relatively specific and detailed, but it should not be construed as limiting the scope of the patent for the invention. It should be noted that those skilled in the art can make several modifications and improvements without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the scope of protection of the patent application should be based on the appended claims.

Claims (10)

1.一种心室容积监测设备,包括图像采集模块和处理器,所述图像采集模块与所述处理器连接;1. A ventricular volume monitoring device, comprising an image acquisition module and a processor, and the image acquisition module is connected with the processor; 所述图像采集模块获取待监测对象的超声成像视频;所述处理器识别单个心动周期内所述超声成像视频的波动区域,获取所述波动区域的灰度总值,根据所述波动区域的灰度总值得到所述待监测对象的腔体面积变化信息,并基于所述腔体面积变化信息得到所述待监测对象的心室容积变化信息。The image acquisition module acquires the ultrasound imaging video of the object to be monitored; the processor identifies the fluctuation area of the ultrasound imaging video in a single cardiac cycle, acquires the total gray value of the fluctuation area, and according to the gray value of the fluctuation area The cavity area change information of the object to be monitored is obtained through the total degree value, and the ventricular volume change information of the object to be monitored is obtained based on the cavity area change information. 2.根据权利要求1所述的设备,其特征在于,所述处理器还用于获取所述波动区域的各灰度值以及像素总值,根据所述各灰度值得到所述波动区域的灰度总值;基于所述波动区域的像素总值不变,根据所述像素总值与所述波动区域的灰度总值,得到所述待监测对象的腔体面积变化信息。2. The device according to claim 1, wherein the processor is further configured to acquire each grayscale value and the total pixel value of the fluctuating region, and obtain the grayscale value of the fluctuating region according to each grayscale value. The total gray value: based on the fact that the total pixel value of the fluctuating area remains unchanged, the cavity area change information of the object to be monitored is obtained according to the total pixel value and the total gray value of the fluctuating area. 3.根据权利要求2所述的设备,其特征在于,所述处理器还用于将所述像素总值与所述波动区域的灰度总值之差作为腔体面积变化值,获取单个心动周期内待监测对象的超声成像视频的帧数及对应的腔体面积变化值,构建所述帧数与所述腔体面积变化值之间的关系曲线。3. The device according to claim 2, wherein the processor is further configured to use the difference between the total pixel value and the total gray value of the fluctuating region as the cavity area change value to obtain a single heart beat The number of frames of the ultrasonic imaging video of the object to be monitored and the corresponding change value of the cavity area within the cycle, and a relationship curve between the number of frames and the change value of the cavity area is constructed. 4.根据权利要求1所述的设备,其特征在于,所述处理器还用于对所述腔体面积变化信息进行滤波平滑处理,基于滤波平滑处理后的腔体面积变化信息得到所述待监测对象的心室容积变化信息。4. The device according to claim 1, wherein the processor is further configured to perform filtering and smoothing processing on the cavity area change information, and obtain the waiting time based on the cavity area change information after filtering and smoothing processing. Monitor the subject's ventricular volume change information. 5.根据权利要求1所述的设备,其特征在于,所述处理器还用于基于预设补偿函数,对所述心室容积变化信息进行校准。5. The device according to claim 1, wherein the processor is further configured to calibrate the ventricular volume change information based on a preset compensation function. 6.根据权利要求1所述的设备,其特征在于,所述处理器还用于当所述待监测对象的超声成像视频为彩色图像视频时,对所述彩色图像视频进行灰度处理,识别单个心动周期内灰度处理后的超声成像视频的波动区域。6. The device according to claim 1, wherein the processor is further configured to perform grayscale processing on the color image video when the ultrasonic imaging video of the object to be monitored is a color image video, and identify Fluctuating regions of a gray-scale processed ultrasound imaging video within a single cardiac cycle. 7.根据权利要求1至6任意一项所述的设备,其特征在于,还包括超声成像采集装置,所述超声成像采集装置与所述处理器连接。7. The device according to any one of claims 1 to 6, further comprising an ultrasonic imaging acquisition device connected to the processor. 8.根据权利要求1至6任意一项所述的设备,其特征在于,还包括显示器,所述显示器与所述处理器连接。8. The device according to any one of claims 1 to 6, further comprising a display connected to the processor. 9.根据权利要求1至6任意一项所述的设备,其特征在于,还包括记录仪,所述记录仪与所述处理器连接。9. The device according to any one of claims 1 to 6, further comprising a recorder connected to the processor. 10.一种心室容积监测方法,其特征在于,所述方法包括:10. A method for monitoring ventricular volume, characterized in that the method comprises: 获取待监测对象的超声成像视频;Obtain the ultrasound imaging video of the object to be monitored; 识别单个心动周期内所述超声成像视频的波动区域;identifying regions of fluctuation in the ultrasound imaging video within a single cardiac cycle; 获取所述波动区域的灰度总值,根据所述波动区域的灰度总值得到所述待监测对象的腔体面积变化信息;Acquiring the total gray value of the fluctuating area, and obtaining the cavity area change information of the object to be monitored according to the total gray value of the fluctuating area; 基于所述待监测对象的腔体面积变化信息得到所述待监测对象的心室容积变化信息。The ventricular volume change information of the subject to be monitored is obtained based on the cavity area change information of the subject to be monitored.
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