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CN108653149B - Whitening and moisturizing mask and preparation method thereof - Google Patents

Whitening and moisturizing mask and preparation method thereof Download PDF

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CN108653149B
CN108653149B CN201810809295.5A CN201810809295A CN108653149B CN 108653149 B CN108653149 B CN 108653149B CN 201810809295 A CN201810809295 A CN 201810809295A CN 108653149 B CN108653149 B CN 108653149B
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CN108653149A (en
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李媛媛
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Baikangli medical technology (Shanghai) Co.,Ltd.
Zhongke Huzhou Applied Technology Research Institute
Zhongke Lijian medical technology (Huzhou) Co.,Ltd.
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Baikangli Medical Technology Shanghai Co ltd
Zhongke Huzhou Applied Technology Research Institute
Zhongke Lijian Medical Technology Huzhou Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9755Gymnosperms [Coniferophyta]
    • A61K8/9767Pinaceae [Pine family], e.g. pine or cedar
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract

The invention aims to provide a whitening and moisturizing mask which has the advantages of outstanding synergistic moisturizing and whitening effects, good soothing and anti-allergy effects, high stability, good lubrication feeling and small skin irritation and a preparation method thereof. The invention discloses a whitening and moisturizing mask which is prepared from the following raw materials in parts by weight: 2-2.5 parts of tremella polysaccharide, 1.5-2 parts of serine, 1-1.5 parts of maltodextrin, 8-10 parts of hawthorn seed oil, 1-1.5 parts of sodium lauroyl lactylate, 70-90 parts of deionized water, 0.6-0.8 part of carbomer, 0.4-0.5 part of xanthan gum, 3.5-4 parts of sodium isostearoyl lactylate, 4.5-5 parts of bulbus fritillariae cirrhosae fermentation extract, 3.5-4 parts of blunt drug stauntonvine fermentation extract, 4.5-5 parts of pollen pini and 3.5-4 parts of cocoyl malic amino acid sodium.

Description

Whitening and moisturizing mask and preparation method thereof
Technical Field
The invention belongs to the technical field of biology and cosmetics, and particularly relates to a whitening and moisturizing mask and a preparation method thereof.
Background
The whitening components in the general cosmetics mainly comprise arbutin, kojic acid, tartaric acid and vitamin C. Arbutin is a whitening component extracted from bearberry plants, and can inhibit the activity of tyrosinase (a key enzyme for synthesizing melanin in skin), thereby achieving the effect of reducing melanin synthesis. Kojic acid is a fungal metabolite, and the whitening principle of the kojic acid is similar to that of arbutin, but the kojic acid has a much stronger effect and is commonly used for medical whitening. The fruit acid is an organic acid extracted from fruits, and its whitening principle is to make keratinocytes shed off, thereby making melanin existing in the keratinocytes shed off together. Vitamin C is the most classical whitening ingredient, it not only inhibits melanin formation, but also has excellent antioxidant properties to eliminate the original melanin. The skin has a plurality of moisture-keeping components, and hyaluronic acid (hyaluronic acid) has very strong water absorption capacity, can absorb water which is several times higher than the hyaluronic acid, and enables cutin water to be full in a short time. So that the elastic fibers and the collagen are in an environment full of moisture and are more moist and elastic relative to the skin. Is the strongest component in the aspect of water locking and moisture preservation in the natural world at present. The natural moisturizing factor NMF contains compounds of amino acid, sodium lactate, urea and the like, has strong hygroscopicity, can adjust the pH value of skin, and maintains the normal operation of keratinocytes. Hydrolysis of collagen the macromolecular collagen is treated hydrolytically to small molecules. Supplementing 17 amino acids beneficial to human body, maintaining stratum corneum water content and fiber structure integrity, improving skin cell living environment and promoting skin tissue metabolism to achieve the effects of moistening skin and delaying aging.
Disclosure of Invention
The invention aims to provide a whitening and moisturizing mask which has the advantages of outstanding synergistic moisturizing and whitening effects, good soothing and anti-allergy effects, high stability, good lubrication feeling and small skin irritation and a preparation method thereof.
The invention discloses a whitening and moisturizing mask which is prepared from the following raw materials in parts by weight: 2-2.5 parts of tremella polysaccharide, 1.5-2 parts of serine, 1-1.5 parts of maltodextrin, 8-10 parts of hawthorn seed oil, 1-1.5 parts of sodium lauroyl lactylate, 70-90 parts of deionized water, 0.6-0.8 part of carbomer, 0.4-0.5 part of xanthan gum, 3.5-4 parts of sodium isostearoyl lactylate, 4.5-5 parts of bulbus fritillariae cirrhosae fermentation extract, 3.5-4 parts of blunt drug stauntonvine fermentation extract, 4.5-5 parts of pollen pini and 3.5-4 parts of cocoyl malic amino acid sodium.
The whitening and moisturizing mask is prepared from the following raw materials in parts by weight: 2.2 parts of tremella polysaccharide, 1.8 parts of serine, 1.4 parts of maltodextrin, 9 parts of hawthorn seed oil, 1.3 parts of sodium lauroyl lactylate, 82 parts of deionized water, 0.7 part of carbomer, 0.4 part of xanthan gum, 3.8 parts of sodium isostearoyl lactylate, 4.8 parts of bulbus fritillariae cirrhosae fermentation extract, 3.8 parts of blunt drug stauntonvine fermentation extract, 4.6 parts of pollen pini and 3.6 parts of cocoyl malic acid sodium salt.
The method for preparing the whitening and moisturizing mask comprises the following steps:
(1) mixing the tremella polysaccharide, the serine and the maltodextrin in parts by weight, adding the mixture into purified water in an amount which is 20 times of the weight of the tremella polysaccharide, uniformly stirring the mixture, drying the mixture at the temperature of 40-45 ℃, and grinding the mixture into powder to obtain powder A;
(2) mixing and heating the hawthorn seed oil and the sodium lauroyl lactylate to 70-75 ℃ and uniformly mixing and stirring the mixture and the powder A;
(3) mixing the deionized water, the carbomer and the xanthan gum in parts by weight, heating to 50-55 ℃, and uniformly stirring; then adding the sodium isostearoyl lactylate and the mixture obtained in the step (2) in parts by weight, and uniformly stirring;
(4) adding the bulbus fritillariae cirrhosae fermented extract, the blunt drug stauntonvine fermented extract, the pollen pini and the cocoyl malic acid sodium salt into the mixture obtained in the step (3) in parts by weight, and stirring uniformly at the temperature of 40-45 ℃; cooling and discharging to obtain the product.
In the components of the invention, the hawthorn seed oil contains rich squalane, vitamin E, polyphenol, flavone and other components, and has good oxidation resistance and the effects of repairing and moistening skin. Serine is a non-essential amino acid and has the function of keeping the moisture of the stratum corneum of the skin. The tremella polysaccharide can achieve the effects of moisturizing and nourishing skin, and can make the skin moist and smooth. Maltodextrin is used as adsorbent and emulsion stabilizer.
The sodium lauroyl lactylate has excellent decontamination, emulsification, solubilization, dispersion and lubrication capability. Sodium isostearoyl lactylate is a mild anionic surfactant and emulsifier, and has strong lubricating feeling and film forming property. Sodium cocoyl malate is a very mild surfactant of plant origin.
The Bulbus Fritillariae Cirrhosae fermented extract is Lactobacillus acidophilus extract, and has outstanding effects of inhibiting hyaluronidase, relieving and resisting allergy; the preparation method comprises the steps of cleaning and crushing the bulbus fritilariae to 50-60 meshes, adding 18-20 times of distilled water, and carrying out autoclaving at the temperature of 115-121 ℃ for 15-30 min; inoculating activated lactobacillus acidophilus with the inoculation amount of 2-3%, and fermenting for 3-5 days at 28-32 ℃; and homogenizing and crushing the fermentation liquor by using a high-pressure homogenizer, centrifuging for 10-12 minutes at 5000-6000 r/min, taking supernatant, concentrating under vacuum and reducing pressure, and freeze-drying to obtain the product.
Hyaluronic Acid (HA) is distributed in the extracellular matrix, is a main component constituting the extracellular matrix and the intercellular substance, and is hydrolyzed by hyaluronidase, which causes non-adhesion between cells, causes degranulation of cells and exudation of new synthesized media, exerts biological effects, and often causes immediate-type hypersensitivity. Hyaluronidase inhibition assay:
the hyaluronidase inhibition was determined by the Elson-Morgan method. Adding 0.5 mL of hyaluronidase solution and 0.1mL of 0.25 mmol/L of CaC12 solution into each test tube, and culturing in an incubator at 37 deg.C for 20 min; adding 0.5 mL of Bulbus Fritillariae Cirrhosae fermented extract sample liquid with certain concentration, and culturing at 37 deg.C for 20 min; adding O.5 mL sodium hyaluronate solution, placing in an incubator at 37 ℃ for heat preservation for 30min, taking out, and standing at normal temperature for 5 min; adding 0.1 mL0.4mol/LNaOH solution and 0.5 mL acetylacetone solution, heating in a boiling water bath for 15 min, and immediately cooling for 5 min with ice water; adding 1.0 mL of Ellisib reagent, diluting with 3.0 mL of anhydrous ethanol, standing for 20 min for color development, and measuring the absorbance value with a spectrophotometer. Hyaluronidase inhibition (%): [ (A-B) (C-D) ]/(A-B). times.100%; in the formula: a is the OD value of the control solution; b is the OD value of the control blank solution; c is the OD value of the sample solution to be measured; d is the OD value of the blank of the sample, and the result is shown in FIG. 1. With the increase of the concentration of the fritillaria cirrhosa fermentation extract, when lO g/L is reached, the hyaluronidase inhibition rate is 92.78%. This shows that the fermented extract of Bulbus Fritillariae Cirrhosae can reduce the decomposition of hyaluronic acid by inhibiting the activity of hyaluronic acid enzyme, and further reduce the release amount of histamine and inflammatory factor, thereby playing a certain role in resisting allergy and irritation.
The blunted stauntonvine fermented extract is an extract of blunted stauntonvine (Stauntonia leucoantha Diels ex Y.C.Wu) after fermentation, can promote melanin metabolism, inhibit and destroy melanin generation, has the outstanding effect of whitening skin, and can be extracted by the following method: crushing the blunt medicinal stauntonvine, adding the crushed blunt medicinal stauntonvine into a fermentation tank, and adding distilled water according to the feed-liquid ratio of 1: 9; inoculating activated and cultured pediococcus cerevisiae for fermentation, wherein the inoculation amount is 1.5-2.5%; fermenting for 24-36 hours at 28-30 ℃; then carrying out ultrasonic extraction for 3 times at 70-80 ℃, carrying out ultrasonic extraction at the frequency of 60kHz and the power of 330W for 30-60 minutes each time, filtering, combining filtrates, centrifuging for 10 minutes at 8000r/min, taking supernatant, and concentrating under reduced pressure to obtain an extract. The pine pollen is sperm cells of pistil of pine, also known as pine pollen, contains rich amino acids, all natural vitamins and various enzymes, and can enhance skin metabolism, increase skin elasticity and delay skin aging.
In the whitening and moisturizing mask, pine pollen and wild papaya fermented extracts serving as blunt medicines are used as synergistic whitening components, so that the whitening effect is remarkable. Bulbus Fritillariae Cirrhosae fermented extract has outstanding effects of inhibiting hyaluronidase, relieving and resisting allergy. The tremella polysaccharide, the serine and the hawthorn seed oil form the composite moisturizing factor, and the moisturizing effect is obvious. The whitening and moisturizing mask disclosed by the invention is high in stability, good in lubrication feeling and small in skin irritation.
Drawings
FIG. 1 is a graph showing the results of the inhibition ratios of hyaluronidase at various concentrations.
Detailed Description
The following examples are intended to further illustrate the present invention and should not be construed as limiting the scope of the invention, and other insubstantial modifications and adaptations of the invention by those skilled in the art based on the teachings herein are intended to be covered thereby.
Example 1: the whitening and moisturizing mask is prepared by the following steps:
(1) mixing 2.2 parts of tremella polysaccharide, 1.8 parts of serine and 1.4 parts of maltodextrin, adding the mixture into 20 times of purified water by weight, uniformly stirring, drying at 40-45 ℃, and grinding to prepare powder A;
(2) mixing and heating 9 parts of hawthorn seed oil and 1.3 parts of sodium lauroyl lactylate to 70-75 ℃, and uniformly mixing and stirring the mixture and the powder A;
(3) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 4.8 parts of bulbus fritillariae cirrhosae fermented extract, 3.8 parts of blunt-drug stauntonvine fermented extract, 4.6 parts of pollen pini and 3.6 parts of sodium cocoyl malate into the mixture obtained in the step (3), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Example 2: the whitening and moisturizing mask is prepared by the following steps:
(1) mixing 2 parts of tremella polysaccharide, 1.5 parts of serine and 1 part of maltodextrin, adding the mixture into purified water of which the weight is 20 times that of the tremella polysaccharide, uniformly stirring the mixture, drying the mixture at the temperature of 40-45 ℃, and grinding the mixture into powder;
(2) mixing 8 parts of hawthorn seed oil and 1 part of sodium lauroyl lactylate, heating to 70-75 ℃, and uniformly mixing and stirring with the powder in the step (1);
(3) mixing 70 parts of deionized water, 0.6 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.5 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 4.5 parts of bulbus fritillariae cirrhosae fermented extract, 3.5 parts of blunt-drug stauntonvine fermented extract, 4.5 parts of pollen pini and 3.5 parts of sodium cocoyl malate into the mixture obtained in the step (3), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Example 3: the whitening and moisturizing mask is prepared by the following steps:
(1) mixing 2.5 parts of tremella polysaccharide, 2 parts of serine and 1.5 parts of maltodextrin, adding the mixture into purified water of which the weight is 20 times that of the tremella polysaccharide, uniformly stirring the mixture, drying the mixture at the temperature of 40-45 ℃, and grinding the mixture into powder;
(2) mixing 10 parts of hawthorn seed oil and 1.5 parts of sodium lauroyl lactylate, heating to 70-75 ℃, and uniformly mixing and stirring with the powder in the step (1);
(3) mixing 90 parts of deionized water, 0.8 part of carbomer and 0.5 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 4 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 5 parts of bulbus fritillariae cirrhosae fermentation extract, 4 parts of blunt drug stauntonvine fermentation extract, 5 parts of pollen pini and 4 parts of cocoyl malic acid sodium salt into the mixture in the step (3), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Comparative example 1: the mask is prepared by the following steps:
(1) mixing and heating 9 parts of hawthorn seed oil, 1.3 parts of sodium lauroyl lactylate, 2.2 parts of tremella polysaccharide and 1.4 parts of maltodextrin to 70-75 ℃, and uniformly stirring;
(2) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (1), and uniformly stirring;
(3) adding 4.8 parts of bulbus fritillariae cirrhosae fermented extract, 3.8 parts of blunt drug stauntonvine fermented extract, 4.6 parts of pollen pini and 3.6 parts of sodium cocoyl malate into the mixture in the step (2), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Comparative example 2: the mask is prepared by the following steps:
(1) mixing and heating 9 parts of hawthorn seed oil, 1.3 parts of sodium lauroyl lactylate, 1.8 parts of serine and 1.4 parts of maltodextrin to 70-75 ℃, and uniformly stirring;
(2) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (1), and uniformly stirring;
(3) adding 4.8 parts of bulbus fritillariae cirrhosae fermented extract, 3.8 parts of blunt drug stauntonvine fermented extract, 4.6 parts of pollen pini and 3.6 parts of sodium cocoyl malate into the mixture in the step (2), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Comparative example 3: the mask is prepared by the following steps:
(1) mixing 9 parts of glycerol, 1.3 parts of sodium lauroyl lactylate, 2.2 parts of tremella polysaccharide, 1.8 parts of serine and 1.4 parts of maltodextrin, heating to 70-75 ℃, and uniformly stirring;
(2) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (1), and uniformly stirring;
(3) adding 4.8 parts of bulbus fritillariae cirrhosae fermented extract, 3.8 parts of blunt drug stauntonvine fermented extract, 4.6 parts of pollen pini and 3.6 parts of sodium cocoyl malate into the mixture in the step (2), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
And (4) testing the moisturizing effect: the moisture content was measured using a moisture tester Corneometer (CM825, C + K Corp., Germany). The unit a.c.u. measurement used for its measurement ranged from 0 to 120 a.c.u.; the water loss rate was measured using a skin water loss (TEWL) tester, Tewameter (TM 300, C + K, Germany), and the more intact the skin protective layer, the higher the water content and the lower the TEWL value of the skin water loss. And (3) measuring environment: testing the environmental temperature: 22 ± 3 ℃, humidity: 50 +/-5%. A total of 155 subjects were selected and divided into five groups, and examples 1 to 2 and comparative examples 1 to 3 were used. At a rate of 1.75. mu.l/cm per day2The coating density was uniformly applied twice, the initial values were tested before use, the results were tested after one month, and the rate of change was observed, see table 1. It can be seen that the embodiments of the present invention are employed1 has more outstanding cooperative moisturizing effect compared with the comparative example.
Figure 719113DEST_PATH_IMAGE001
Comparative example 4: the mask is prepared by the following steps:
(1) mixing 2.2 parts of tremella polysaccharide, 1.8 parts of serine and 1.4 parts of maltodextrin, adding the mixture into 20 times of purified water by weight, uniformly stirring, drying at 40-45 ℃, and grinding to prepare powder A;
(2) mixing and heating 9 parts of hawthorn seed oil and 1.3 parts of sodium lauroyl lactylate to 70-75 ℃, and uniformly mixing and stirring the mixture and the powder A;
(3) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 4.8 parts of bulbus fritillariae cirrhosae fermented extract, 3.8 parts of blunt drug stauntonvine fermented extract and 3.6 parts of sodium cocoyl malate into the mixture in the step (3), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
Comparative example 5: the mask is prepared by the following steps:
(1) mixing 2.2 parts of tremella polysaccharide, 1.8 parts of serine and 1.4 parts of maltodextrin, adding the mixture into 20 times of purified water by weight, uniformly stirring, drying at 40-45 ℃, and grinding to prepare powder A;
(2) mixing and heating 9 parts of hawthorn seed oil and 1.3 parts of sodium lauroyl lactylate to 70-75 ℃, and uniformly mixing and stirring the mixture and the powder A;
(3) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 4.8 parts of bulbus fritillariae cirrhosae fermentation extract, 4.6 parts of pollen pini and 3.6 parts of sodium cocoyl malate into the mixture obtained in the step (3), and uniformly stirring at 40-45 ℃; cooling and discharging to obtain the product.
Comparative example 6: the mask is prepared by the following steps:
(1) mixing 2.2 parts of tremella polysaccharide, 1.8 parts of serine and 1.4 parts of maltodextrin, adding the mixture into 20 times of purified water by weight, uniformly stirring, drying at 40-45 ℃, and grinding to prepare powder A;
(2) mixing and heating 9 parts of hawthorn seed oil and 1.3 parts of sodium lauroyl lactylate to 70-75 ℃, and uniformly mixing and stirring the mixture and the powder A;
(3) mixing 82 parts of deionized water, 0.7 part of carbomer and 0.4 part of xanthan gum, heating to 50-55 ℃, and uniformly stirring; then adding 3.8 parts of sodium isostearoyl lactylate and the mixture obtained in the step (2), and uniformly stirring;
(4) adding 4.8 parts of bulbus fritillariae cirrhosae fermentation extract and 3.6 parts of sodium cocoyl malate into the mixture in the step (3), and stirring uniformly at 40-45 ℃; cooling and discharging to obtain the product.
And (3) testing the whitening effect: a skin pigment instrument MeXAMETER MX18, manufactured by Courage + Khazaka Company (CK) Germany, was used; lab colorimetric system Spectrophotometer. And (3) measuring environment: testing the environmental temperature: 22 ± 3 ℃, humidity: 50 +/-5%. 155 female volunteers were selected and divided into 5 groups; the masks of examples 1 and 3 and comparative examples 4 to 6 were applied uniformly twice a day for 30 consecutive days at a coating density of 1.75. mu.l/cm 2. The change in skin color was measured using a Lab colorimetric system spectrophotometer: continuously testing for 3 times, taking L*Value average. And simultaneously measuring the content of the skin melanochrome by using a MEXAMETER MX18 skin pigment instrument: the test was performed 3 times in succession and the average value was taken. The results are shown in Table 2, and it can be seen from Table 2 that the melanin content is significantly reduced, L, after 30 days of use in example 1 compared to comparative examples 1-3*The value is obviously increased, and the synergistic whitening and freckle removing effects of the pine pollen and the blunt-drug stauntonvine fermented extract are obvious.
Figure 980461DEST_PATH_IMAGE002

Claims (3)

1. The whitening and moisturizing mask is characterized by being prepared from the following raw materials in parts by weight: 2-2.5 parts of tremella polysaccharide, 1.5-2 parts of serine, 1-1.5 parts of maltodextrin, 8-10 parts of hawthorn seed oil, 1-1.5 parts of sodium lauroyl lactylate, 70-90 parts of deionized water, 0.6-0.8 part of carbomer, 0.4-0.5 part of xanthan gum, 3.5-4 parts of sodium isostearoyl lactylate, 4.5-5 parts of a bulbus fritillariae cirrhosae fermentation extract, 3.5-4 parts of a blunt drug stauntonvine fermentation extract, 4.5-5 parts of pollen pini and 3.5-4 parts of cocoyl malic amino acid sodium;
the bulbus fritillariae cirrhosae fermented extract is obtained by the following method, the bulbus fritillariae cirrhosae is cleaned and crushed to 50-60 meshes, then 18-20 times of distilled water is added, and autoclaving is carried out at the temperature of 115-121 ℃ for 15-30 min; inoculating activated lactobacillus acidophilus with the inoculation amount of 2-3%, and fermenting for 3-5 days at 28-32 ℃; and homogenizing and crushing the fermentation liquor by using a high-pressure homogenizer, centrifuging for 10-12 minutes at 5000-6000 r/min, taking supernatant, concentrating under vacuum and reducing pressure, and freeze-drying to obtain the product.
2. The whitening and moisturizing mask as claimed in claim 1, which is characterized by being prepared from the following raw materials in parts by weight: 2.2 parts of tremella polysaccharide, 1.8 parts of serine, 1.4 parts of maltodextrin, 9 parts of hawthorn seed oil, 1.3 parts of sodium lauroyl lactylate, 82 parts of deionized water, 0.7 part of carbomer, 0.4 part of xanthan gum, 3.8 parts of sodium isostearoyl lactylate, 4.8 parts of bulbus fritillariae cirrhosae fermentation extract, 3.8 parts of blunt drug stauntonvine fermentation extract, 4.6 parts of pollen pini and 3.6 parts of cocoyl malic acid sodium salt.
3. A method for preparing the whitening and moisturizing mask as claimed in any one of the preceding claims, characterized by comprising the steps of:
(1) mixing the tremella polysaccharide, the serine and the maltodextrin in parts by weight, adding the mixture into purified water in an amount which is 20 times of the weight of the tremella polysaccharide, uniformly stirring the mixture, drying the mixture at the temperature of 40-45 ℃, and grinding the mixture into powder to obtain powder A;
(2) mixing and heating the hawthorn seed oil and the sodium lauroyl lactylate to 70-75 ℃ and uniformly mixing and stirring the mixture and the powder A;
(3) mixing the deionized water, the carbomer and the xanthan gum in parts by weight, heating to 50-55 ℃, and uniformly stirring; then adding the sodium isostearoyl lactylate and the mixture obtained in the step (2) in parts by weight, and uniformly stirring;
(4) adding the bulbus fritillariae cirrhosae fermented extract, the blunt drug stauntonvine fermented extract, the pollen pini and the cocoyl malic acid sodium salt into the mixture obtained in the step (3) in parts by weight, and stirring uniformly at the temperature of 40-45 ℃; cooling and discharging to obtain the product.
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Citations (1)

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Publication number Priority date Publication date Assignee Title
CN107184486A (en) * 2017-07-06 2017-09-22 曾万祥 A kind of facial mask liquid and the facial mask containing the facial mask liquid

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184486A (en) * 2017-07-06 2017-09-22 曾万祥 A kind of facial mask liquid and the facial mask containing the facial mask liquid

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* Cited by examiner, † Cited by third party
Title
山楂籽油的体内抗氧化功能研究;范学辉等;《江西农业学报》;20071231;第19卷(第10期);第111-112页 *
钝药野木瓜中三萜类化合物分离及其含量测定;胡冬群等;《中国民族民间医药》;20180228;第27卷(第4期);第9-13页 *

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