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CN108653014A - A kind of whitening patch-lightening cosmetic and preparation method thereof - Google Patents

A kind of whitening patch-lightening cosmetic and preparation method thereof Download PDF

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CN108653014A
CN108653014A CN201810690855.XA CN201810690855A CN108653014A CN 108653014 A CN108653014 A CN 108653014A CN 201810690855 A CN201810690855 A CN 201810690855A CN 108653014 A CN108653014 A CN 108653014A
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whitening
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刘丹
毛贻琴
丁利君
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Guangdong University of Technology
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Cosmetics (AREA)

Abstract

本发明属于化妆品领域,尤其涉及一种美白淡斑化妆品及其制备方法。本发明提供了一种美白淡斑化妆品,以重量份计,由以下组分制成:基础油10~13份、羟丙基‑β‑环糊精6~11份、显齿蛇葡萄提取物6~11份、植物乳化剂4~7份、透明质酸0.01~0.05份、Vc粉3~5份、多元醇类保湿剂8~12份、增稠剂0.1~0.5份、防腐剂0.2~0.8份和水30~60份。本发明美白淡斑化妆品中,羟丙基‑β‑环糊精和显齿蛇葡萄提取物协同作用,增加了显齿蛇葡萄提取物在美白淡斑化妆品中的溶解性,使显齿蛇葡萄提取物更好地发挥其作用,也更好的发挥了羟丙基‑β‑环糊精在美白淡斑化妆品中的稳定作用,使美白淡斑化妆品具有更好的美白效果,并且,该化妆品中不含对人体有害的成分,对皮肤无刺激性,不会引起过敏反应。The invention belongs to the field of cosmetics, and in particular relates to a whitening and lightening cosmetic and a preparation method thereof. The invention provides a whitening and lightening cosmetic, which is made of the following components in parts by weight: 10-13 parts of base oil, 6-11 parts of hydroxypropyl-β-cyclodextrin, and extract 6-11 parts, 4-7 parts of plant emulsifier, 0.01-0.05 parts of hyaluronic acid, 3-5 parts of Vc powder, 8-12 parts of polyol moisturizing agent, 0.1-0.5 parts of thickener, 0.2-0 parts of preservative 0.8 parts and 30-60 parts of water. In the whitening and lightening cosmetics of the present invention, the synergistic effect of hydroxypropyl-β-cyclodextrin and the extract of Snake-toothed Grape increases the solubility of the extract of Snake-toothed Grape in the whitening and light-spotting cosmetics, making the The extract plays its role better, and also better plays the stabilizing effect of hydroxypropyl-β-cyclodextrin in the whitening and blemish cosmetics, so that the whitening and blemish cosmetics have better whitening effect, and the cosmetics It does not contain harmful ingredients to the human body, is non-irritating to the skin, and will not cause allergic reactions.

Description

一种美白淡斑化妆品及其制备方法A kind of whitening cosmetic and preparation method thereof

技术领域technical field

本发明属于化妆品领域,尤其涉及一种美白淡斑化妆品及其制备方法。The invention belongs to the field of cosmetics, and in particular relates to a whitening and lightening cosmetic and a preparation method thereof.

背景技术Background technique

当皮肤被紫外线照射时,会产生并释放决定皮肤颜色的黑色素,从而引起色素沉着过度,如黑斑病、雀斑和斑点,它们均对美容产生不好的影响。黑色素的合成过程如下:细胞中的络氨酸酶对络氨酸作用形成多巴醌,从而产生黑色素。因此,为了防止皮肤变黑,研究人员致力于研究抑制黑色素的合成,从而减少黑色素自身的合成。When the skin is irradiated by ultraviolet rays, melanin, which determines the color of the skin, is produced and released, causing hyperpigmentation such as melasma, freckles, and spots, all of which have adverse effects on beauty. The synthesis process of melanin is as follows: tyrosinase in cells acts on tyrosine to form dopaquinone, thereby producing melanin. Therefore, in order to prevent darkening of the skin, researchers have devoted themselves to research on inhibiting the synthesis of melanin, thereby reducing the synthesis of melanin itself.

目前,化妆品领域中的大部分原料是在单一机理或几种机理结合上去实现美白淡斑的目的,但这些原料运用到化妆品中的功能效果不尽人意,一方面原料自身会有缺陷,另一方面很难加入到配方体系中,给配方带来极大困难,或者容易变色,或者对皮肤刺激性偏大,导致过敏率偏高,或者没有效果等。传统的祛斑产品中常添加熊果苷、氧化亚油酸、重金属、曲酸、氢醌等,这些物质不仅对皮肤刺激性很大,甚至会引起过敏反应。At present, most raw materials in the field of cosmetics achieve the purpose of whitening and lightening spots through a single mechanism or a combination of several mechanisms, but the functional effects of these raw materials used in cosmetics are not satisfactory. On the one hand, the raw materials themselves have defects, and on the other hand On the one hand, it is difficult to add to the formulation system, which brings great difficulties to the formulation, or is easy to change color, or is too irritating to the skin, resulting in a high allergy rate, or has no effect. Arbutin, oxidized linoleic acid, heavy metals, kojic acid, hydroquinone, etc. are often added to traditional freckle products. These substances are not only very irritating to the skin, but may even cause allergic reactions.

发明内容Contents of the invention

有鉴于此,本发明提供一种美白淡斑化妆品及其制备方法,用于解决现有美白淡斑化妆品中常添加熊果苷、曲酸、蒽醌等,对皮肤刺激性很大,甚至会引起过敏反应的问题。In view of this, the present invention provides a whitening and blemish-reducing cosmetic and a preparation method thereof, which are used to solve the problem that arbutin, kojic acid, anthraquinone, etc. are often added in existing whitening and blemish-reducing cosmetics, which are very irritating to the skin and even cause The problem of allergic reactions.

本发明的具体技术方案如下:Concrete technical scheme of the present invention is as follows:

一种美白淡斑化妆品,以重量份计,由以下组分制成:基础油10~13份、羟丙基-β-环糊精6~11份、显齿蛇葡萄提取物6~11份、植物乳化剂4~7份、透明质酸0.01~0.05份、Vc粉3~5份、多元醇类保湿剂8~12份、增稠剂0.1~0.5份、防腐剂0.2~0.8份和水30~60份。A whitening and blemish-reducing cosmetic, made up of the following components in parts by weight: 10-13 parts of base oil, 6-11 parts of hydroxypropyl-β-cyclodextrin, and 6-11 parts of snake-toothed grape extract , 4-7 parts of plant emulsifier, 0.01-0.05 part of hyaluronic acid, 3-5 parts of Vc powder, 8-12 parts of polyol moisturizer, 0.1-0.5 part of thickener, 0.2-0.8 part of preservative and water 30-60 servings.

优选的,以重量份计,由以下组分制成:基础油10份、羟丙基-β-环糊精8份、显齿蛇葡萄提取物8份、植物乳化剂5份、透明质酸0.03份、Vc粉4份、多元醇类保湿剂10份、增稠剂0.3份、防腐剂0.5份和水53.67份。Preferably, in parts by weight, it is made of the following components: 10 parts of base oil, 8 parts of hydroxypropyl-β-cyclodextrin, 8 parts of Snake dentata extract, 5 parts of plant emulsifier, hyaluronic acid 0.03 parts, 4 parts of Vc powder, 10 parts of polyols moisturizing agent, 0.3 parts of thickener, 0.5 parts of preservative and 53.67 parts of water.

优选的,所述显齿蛇葡萄提取物中的二氢杨梅素含量为23.40wt%~40.66wt%。Preferably, the content of dihydromyricetin in the extract of S. dentatus is 23.40wt%-40.66wt%.

优选的,所述基础油为乳木果油和荷荷巴油的混合物;Preferably, the base oil is a mixture of shea butter and jojoba oil;

所述乳木果油与所述荷荷巴油的质量比为3~8:4~7。The mass ratio of the shea butter to the jojoba oil is 3-8:4-7.

优选的,所述多元醇类保湿剂为丙三醇和丁二醇的混合物;Preferably, the polyhydric alcohol moisturizing agent is a mixture of glycerol and butanediol;

所述丙三醇和所述丁二醇的质量比为3~8:7~12。The mass ratio of the glycerol to the butanediol is 3-8:7-12.

优选的,所述显齿蛇葡萄提取物由以下方法制得:Preferably, the extract of the snake grape is prepared by the following method:

将显齿蛇葡萄幼嫩茎叶加入水中,煮沸,用乙酸乙酯萃取后除去多糖,得到所述显齿蛇葡萄提取物。Adding the young stems and leaves of Grape dentata into water, boiling, extracting with ethyl acetate and removing polysaccharides, so as to obtain the extract of Grape dentatus.

本发明还提供了一种美白淡斑化妆品的制备方法,包括以下步骤:The present invention also provides a preparation method of whitening and lightening cosmetics, comprising the following steps:

a)以质量份计,将7~13份基础油和4~7份植物乳化剂混合后加热至63℃~80℃,再加入0.2~0.8份防腐剂,均质后得到油相;a) In parts by mass, mix 7-13 parts of base oil and 4-7 parts of vegetable emulsifier, heat to 63°C-80°C, add 0.2-0.8 parts of preservative, and homogenize to obtain an oil phase;

b)以质量份计,将6~11份羟丙基-β-环糊精、6~11份显齿蛇葡萄提取物、0.01~0.05份透明质酸、8~12份多元醇类保湿剂和0.1~0.5份增稠剂混合后加水,加热至65℃~80℃,均质后得到水相;b) In terms of parts by mass, 6-11 parts of hydroxypropyl-β-cyclodextrin, 6-11 parts of Snaketodon grape extract, 0.01-0.05 parts of hyaluronic acid, and 8-12 parts of polyol moisturizers Mix with 0.1-0.5 parts of thickener, add water, heat to 65°C-80°C, and obtain the water phase after homogenization;

c)将步骤b)所述水相降温至40℃~50℃,加入步骤a)所述油相和3~5份Vc粉,再在真空环境下均质,得到美白淡斑化妆品;c) cooling the water phase in step b) to 40°C to 50°C, adding the oil phase in step a) and 3 to 5 parts of Vc powder, and then homogenizing in a vacuum environment to obtain a whitening and lightening cosmetic;

其中,所述基础油为乳木果油和荷荷巴油的混合物。Wherein, the base oil is a mixture of shea butter and jojoba oil.

优选的,所述步骤a)具体为:Preferably, said step a) is specifically:

以质量份计,将7~13份所述基础油和4~7份所述植物乳化剂混合后加热至75℃,再加入0.2~0.8份所述防腐剂,均质后得到所述油相。In parts by mass, mix 7-13 parts of the base oil and 4-7 parts of the vegetable emulsifier, heat to 75°C, add 0.2-0.8 parts of the preservative, and homogenize to obtain the oil phase .

优选的,所述步骤b)具体为:Preferably, the step b) is specifically:

以质量份计,将6~11份所述羟丙基-β-环糊精、6~11份所述显齿蛇葡萄提取物、0.01~0.05份所述透明质酸、8~12份所述多元醇类保湿剂和0.1~0.5份所述增稠剂混合后加水,加热至70℃,均质后得到所述水相。In terms of parts by mass, 6-11 parts of the hydroxypropyl-β-cyclodextrin, 6-11 parts of the said velocarpus extract, 0.01-0.05 parts of the hyaluronic acid, 8-12 parts of the The polyhydric alcohol moisturizing agent and 0.1-0.5 part of the thickener are mixed, then water is added, heated to 70°C, and homogenized to obtain the water phase.

优选的,所述步骤c)具体为:Preferably, the step c) is specifically:

将步骤b)所述水相降温至40℃~50℃,加入步骤a)所述油相和3~5份所述Vc粉的混合液,再在真空环境下均质,得到所述美白淡斑化妆品。Cool the water phase in step b) to 40°C to 50°C, add the oil phase in step a) and 3 to 5 parts of the Vc powder mixture, and then homogenize in a vacuum environment to obtain the whitening light spot cosmetics.

综上所述,本发明提供了一种美白淡斑化妆品,以重量份计,由以下组分制成:基础油10~13份、羟丙基-β-环糊精6~11份、显齿蛇葡萄提取物6~11份、植物乳化剂4~7份、透明质酸0.01~0.05份、Vc粉3~5份、多元醇类保湿剂8~12份、增稠剂0.1~0.5份、防腐剂0.2~0.8份和水30~60份。本发明美白淡斑化妆品可以有效的发挥各成分的作用,有效分解黑色素,淡化各种色斑,达到美白淡斑的效果;透明质酸具有非常强大的持水、锁水能力,普遍存在于细胞间基质中在人体皮肤真皮层含量最多,具有保持皮肤水分,使皮肤光滑且富有弹性的作用;羟丙基-β-环糊精和显齿蛇葡萄提取物协同作用,增加了显齿蛇葡萄提取物在美白淡斑化妆品中的溶解性,使显齿蛇葡萄提取物更好地发挥其作用,也更好的发挥了羟丙基-β-环糊精在美白淡斑化妆品中的稳定作用,使美白淡斑化妆品具有更好的美白效果;本发明美白淡斑化妆品中不含对人体有害的成分,对皮肤无刺激性,不会引起过敏反应,是安全有效的美白淡斑乳。In summary, the present invention provides a whitening and blemish-reducing cosmetic, which is made of the following components in parts by weight: 10-13 parts of base oil, 6-11 parts of hydroxypropyl-β-cyclodextrin, Serpentine grape extract 6-11 parts, plant emulsifier 4-7 parts, hyaluronic acid 0.01-0.05 parts, Vc powder 3-5 parts, polyol moisturizing agent 8-12 parts, thickener 0.1-0.5 parts , 0.2-0.8 parts of preservatives and 30-60 parts of water. The whitening and spot-lightening cosmetics of the present invention can effectively play the role of each component, effectively decompose melanin, dilute various stains, and achieve the effect of whitening and lightening spots; hyaluronic acid has a very strong water-holding and water-locking ability, and is commonly found in cells Among the intermatrix, the dermis layer of human skin has the most content, and it has the function of maintaining skin moisture and making the skin smooth and elastic; the synergistic effect of hydroxypropyl-β-cyclodextrin and the extract of Snake Grape The solubility of the extract in whitening and spot-lightening cosmetics enables the extract of Snake-toothed Snake Grape to play its role better, and it also better exerts the stabilizing effect of hydroxypropyl-β-cyclodextrin in whitening and spot-lightening cosmetics , so that the whitening and spot-lightening cosmetics have better whitening effect; the whitening and spot-lightening cosmetics of the present invention do not contain harmful ingredients to the human body, are non-irritating to the skin, do not cause allergic reactions, and are safe and effective whitening and spot-lightening creams.

具体实施方式Detailed ways

本发明提供一种美白淡斑化妆品及其制备方法,用于解决现有美白淡斑化妆品中常添加熊果苷、曲酸、蒽醌等,对皮肤刺激性很大,甚至会引起过敏反应的问题。The invention provides a whitening and blemish-reducing cosmetic and a preparation method thereof, which are used to solve the problem that arbutin, kojic acid, anthraquinone, etc. are often added in existing whitening and blemish-reducing cosmetics, which are very irritating to the skin and even cause allergic reactions .

下面将对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

一种美白淡斑化妆品,以重量份计,由以下组分制成:基础油10~13份、羟丙基-β-环糊精6~11份、显齿蛇葡萄提取物6~11份、植物乳化剂4~7份、透明质酸0.01~0.05份、Vc粉3~5份、多元醇类保湿剂8~12份、增稠剂0.1~0.5份、防腐剂0.2~0.8份和水30~60份。A whitening and blemish-reducing cosmetic, made up of the following components in parts by weight: 10-13 parts of base oil, 6-11 parts of hydroxypropyl-β-cyclodextrin, and 6-11 parts of snake-toothed grape extract , 4-7 parts of plant emulsifier, 0.01-0.05 part of hyaluronic acid, 3-5 parts of Vc powder, 8-12 parts of polyol moisturizer, 0.1-0.5 part of thickener, 0.2-0.8 part of preservative and water 30-60 servings.

本发明中,显齿蛇葡萄(Alnpelopsis grossedentata)是蛇葡萄科蛇葡萄属的一种野生藤本植物。显齿蛇葡萄的幼嫩茎叶中含有丰富的蛋白质、多糖、茶多酚、维生素、黄酮类等物质,具有消炎止痛、降血脂的作用。显齿蛇葡萄主要活性成分为黄酮类化合物,具有清除自由基、抗氧化、抗血栓、抗肿瘤、消炎等多种功效。此外,显齿蛇葡萄还具有抗褐变的效果。本发明美白淡斑化妆品中加入了显齿蛇葡萄提取物,能够明显提高化妆品的抗氧化能力,且能清除多种自由基,延缓肌肤衰老的作用,同时能够通过抑制络氨酸酶活性,减少黑色素生成,从而达到美白祛斑的功效。In the present invention, Alnpelopsis grossedentata is a wild vine of the genus Alnpelopsis grossedentata. The young stems and leaves of the Snake Grape are rich in proteins, polysaccharides, tea polyphenols, vitamins, flavonoids and other substances, which have the effects of anti-inflammatory, analgesic, and blood lipid lowering. The main active ingredients of Snake Grape are flavonoids, which have various functions such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, and anti-inflammatory. In addition, the snake grape also has the effect of anti-browning. The whitening and spot-lightening cosmetics of the present invention add the extract of Snaketodon grape, which can significantly improve the antioxidant capacity of the cosmetics, and can remove various free radicals and delay skin aging. At the same time, it can inhibit the activity of tyrosinase, reduce Melanin is produced, so as to achieve the effect of whitening and freckle removal.

羟丙基-β-环糊精是一种有效的抗粉刺剂,能包接皮肤中渗出的不饱和脂肪酸,防止其氧化变质,抑制自由基形成,并能减少皮肤感染和炎症。同时,羟丙基-β-环糊精能提高美白淡斑化妆品中显齿蛇葡萄提取物的稳定性,显齿蛇葡萄提取物在水中的溶解性很低,羟丙基-β-环糊精对显齿蛇葡萄提取物具有增溶作用,羟丙基-β-环糊精和显齿蛇葡萄提取物协同作用,使显齿蛇葡萄提取物更好地发挥其作用,也更好的发挥了羟丙基-β-环糊精在化妆品中的稳定作用,使美白淡斑化妆品具有更好的美白效果。Hydroxypropyl-β-cyclodextrin is an effective anti-acne agent, which can cover the unsaturated fatty acids exuded from the skin, prevent its oxidative deterioration, inhibit the formation of free radicals, and reduce skin infection and inflammation. At the same time, hydroxypropyl-β-cyclodextrin can improve the stability of the extract of Snake-toothed Grape in whitening and spot-lightening cosmetics. Essence has a solubilizing effect on the extract of Snake Grape It exerts the stabilizing effect of hydroxypropyl-β-cyclodextrin in cosmetics, so that the whitening and lightening cosmetics have better whitening effect.

基础油是从植物的种子、花朵、根茎或果实中萃取的非挥发性油脂,可润滑肌肤,能直接用于肌肤按摩,也是稀释精油的最佳基底油。常见的基础油有乳木果油、荷荷巴油、甜杏仁油、葡萄籽油、玫瑰果油和橄榄油等。Base oil is a non-volatile oil extracted from plant seeds, flowers, rhizomes or fruits. It can lubricate the skin and can be directly used for skin massage. It is also the best base oil for diluting essential oils. Common base oils include shea butter, jojoba oil, sweet almond oil, grapeseed oil, rosehip oil, and olive oil.

Vc粉能清除自由基,起到抗氧化的作用,也可抑制络氨酸酶的形成,从而达到美白祛斑的功效。Vc powder can scavenge free radicals, play an antioxidant role, and also inhibit the formation of tyrosinase, so as to achieve the effect of whitening and removing spots.

透明质酸又名玻璃酸,是一种酸性粘多糖,是目前自然界中保湿性最好的物质。它可以改善皮肤营养代谢,使皮肤柔嫩、光滑、去皱,增加弹性、延缓衰老,在保湿的同时又是良好的透皮吸收促进剂,与其他成分配合使用,可以起到促进吸收的更理想效果。Hyaluronic acid, also known as hyaluronic acid, is an acidic mucopolysaccharide and is currently the most moisturizing substance in nature. It can improve skin nutrient metabolism, make skin soft, smooth, wrinkle-free, increase elasticity, delay aging, and it is a good transdermal absorption accelerator while moisturizing. It can be used in conjunction with other ingredients to promote absorption. Effect.

本发明美白淡斑化妆品是多种淡斑保湿成分的组合,具有显著的美白淡斑,促进肌肤水油平衡的功能,是一种天然、对人体无害且美白效果好的化妆品,配方简单实用,美白淡斑效果好,使用时没有刺激性,不会引起过敏反应。The whitening and spot-lightening cosmetic of the present invention is a combination of various spot-lightening and moisturizing ingredients, which has remarkable whitening and spot-lightening functions, and promotes the function of water-oil balance of the skin. , good whitening effect, non-irritating when used, will not cause allergic reactions.

更优选为,以重量份计,由以下组分制成:基础油10份、羟丙基-β-环糊精8份、显齿蛇葡萄提取物8份、植物乳化剂5份、透明质酸0.03份、Vc粉4份、多元醇类保湿剂10份、增稠剂0.3份、防腐剂0.5份和水53.67份。More preferably, in parts by weight, it is made of the following components: 10 parts of base oil, 8 parts of hydroxypropyl-β-cyclodextrin, 8 parts of Snake dentata grape extract, 5 parts of plant emulsifier, hyaluronic acid 0.03 parts of acid, 4 parts of Vc powder, 10 parts of polyol moisturizer, 0.3 part of thickener, 0.5 part of preservative and 53.67 parts of water.

本发明中,显齿蛇葡萄提取物中的二氢杨梅素含量为23.40wt%~40.66wt%。In the present invention, the content of dihydromyricetin in the extract of S. dentatus is 23.40wt%-40.66wt%.

本发明中,显齿蛇葡萄提取物由以下方法制得:In the present invention, the Snake-toothed Grape extract is prepared by the following method:

将显齿蛇葡萄幼嫩茎叶加入水中,煮沸,用乙酸乙酯萃取后除去多糖,得到显齿蛇葡萄提取物。Adding the young stems and leaves of the Odontodon grape into water, boiling, extracting with ethyl acetate and removing the polysaccharides to obtain the Odontodon grape extract.

更具体的,显齿蛇葡萄提取物由以下方法制得:More specifically, the extract of Snake dentata grape is prepared by the following method:

将显齿蛇葡萄幼嫩茎叶加入蒸馏水中,煮沸,过滤除渣后,用乙酸乙酯萃取,冷却,取上清液,用乙醇除去多糖,真空干燥,得到显齿蛇葡萄提取物。Adding the young stems and leaves of S. edulis to distilled water, boiling, filtering to remove slag, extracting with ethyl acetate, cooling, taking the supernatant, removing polysaccharides with ethanol, and drying in vacuum to obtain S. edulis extract.

二氢杨梅素属于显齿蛇葡萄提取物中的主要活性成分,具有清除自由基、抗氧化、抗血栓、抗肿瘤、消炎等多种功效。Dihydromyricetin is the main active ingredient in the extract of Snake dentata grape, which has various functions such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, and anti-inflammatory.

基础油为乳木果油和荷荷巴油的混合物;The base oil is a blend of shea butter and jojoba oil;

乳木果油与所述荷荷巴油的质量比为3~8:4~7。The mass ratio of the shea butter to the jojoba oil is 3-8:4-7.

乳木果油质地柔嫩幼滑,是最有效的天然保湿品,具有促进细胞再生和修复皮肤水膜的功效,可以柔嫩舒缓皮肤。荷荷巴油含丰富维生素D及蛋白质,是很好的滋润及保湿油,可以维护皮肤水分,预防皱纹以及软化皮肤。Shea butter is soft and smooth, and is the most effective natural moisturizing product. It has the effect of promoting cell regeneration and repairing the skin's water film, and can soften and soothe the skin. Jojoba oil is rich in vitamin D and protein. It is a good moisturizing and moisturizing oil, which can maintain skin moisture, prevent wrinkles and soften the skin.

本发明中,多元醇类保湿剂为丙三醇和丁二醇的混合物;In the present invention, the polyhydric alcohol moisturizing agent is a mixture of glycerol and butanediol;

丙三醇和丁二醇的质量比为3~8:7~12。The mass ratio of glycerol and butanediol is 3-8:7-12.

丙三醇属于半极性分子,对皮肤比较安全。丁二醇保湿性和安全性好,与本发明中的透明质酸复配保湿效果更好。丙三醇和丁二醇的质量比更优选为1:2。Glycerol is a semi-polar molecule and is relatively safe for the skin. Butanediol has good moisture retention and safety, and the moisturizing effect is better when compounded with hyaluronic acid in the present invention. The mass ratio of glycerol and butanediol is more preferably 1:2.

本发明中,美白淡斑化妆品的剂型为乳液,即美白淡斑乳。In the present invention, the dosage form of the whitening and blemish-reducing cosmetic is an emulsion, that is, whitening and blemish-reducing milk.

本发明中,植物乳化剂包括烷基糖苷、单硬脂酸甘油酯、山梨酸醇脂肪酸酯类、磷脂类和糖脂类中的一种或多种。In the present invention, the vegetable emulsifier includes one or more of alkyl glycosides, glycerol monostearate, sorbic acid fatty acid esters, phospholipids and glycolipids.

增稠剂包括聚乙烯醇、聚乙烯吡咯烷酮和丙稀酸聚合物中的一种或多种。Thickeners include one or more of polyvinyl alcohol, polyvinylpyrrolidone and acrylic acid polymers.

防腐剂包括已内酰脲、异噻唑啉酮、对羟基苯甲酸酯、季铵盐-15、苯甲酸、苯甲醇、苯甲酸衍生物和苯甲醇衍生物中的一种或多种。The preservative includes one or more of caprolactone, isothiazolinone, paraben, quaternium-15, benzoic acid, benzyl alcohol, benzoic acid derivatives, and benzyl alcohol derivatives.

本发明美白淡斑化妆品可以有效的发挥各成分的作用,有效分解黑色素,淡化各种色斑,达到美白淡斑的效果;透明质酸具有非常强大的持水、锁水能力,普遍存在于细胞间基质中在人体皮肤真皮层含量最多,具有保持皮肤水分,使皮肤光滑且富有弹性的作用;羟丙基-β-环糊精和显齿蛇葡萄提取物协同作用,增加了显齿蛇葡萄提取物在美白淡斑化妆品中的溶解性,使显齿蛇葡萄提取物更好地发挥其作用,也更好的发挥了羟丙基-β-环糊精在美白淡斑化妆品中的稳定作用,使美白淡斑化妆品具有更好的美白效果;本发明美白淡斑化妆品中不含对人体有害的成分,对皮肤无刺激性,不会引起过敏反应,是安全有效的美白淡斑乳。The whitening and spot-lightening cosmetics of the present invention can effectively play the role of each component, effectively decompose melanin, dilute various stains, and achieve the effect of whitening and lightening spots; hyaluronic acid has a very strong water-holding and water-locking ability, and is commonly found in cells Among the intermatrix, the dermis layer of human skin has the most content, and it has the function of maintaining skin moisture and making the skin smooth and elastic; the synergistic effect of hydroxypropyl-β-cyclodextrin and the extract of Snake Grape The solubility of the extract in whitening and spot-lightening cosmetics enables the extract of Snake-toothed Snake Grape to play its role better, and it also better exerts the stabilizing effect of hydroxypropyl-β-cyclodextrin in whitening and spot-lightening cosmetics , so that the whitening and spot-lightening cosmetics have better whitening effect; the whitening and spot-lightening cosmetics of the present invention do not contain harmful ingredients to the human body, are non-irritating to the skin, do not cause allergic reactions, and are safe and effective whitening and spot-lightening creams.

本发明还提供了一种美白淡斑化妆品的制备方法,包括以下步骤:The present invention also provides a preparation method of whitening and lightening cosmetics, comprising the following steps:

a)以质量份计,将7~13份基础油和4~7份植物乳化剂混合后加热至63℃~80℃,再加入0.2~0.8份防腐剂,均质后得到油相;a) In parts by mass, mix 7-13 parts of base oil and 4-7 parts of vegetable emulsifier, heat to 63°C-80°C, add 0.2-0.8 parts of preservative, and homogenize to obtain an oil phase;

b)以质量份计,将6~11份羟丙基-β-环糊精、6~11份显齿蛇葡萄提取物、0.01~0.05份透明质酸、8~12份多元醇类保湿剂和0.1~0.5份增稠剂混合后加水,加热至65℃~80℃,均质后得到水相;b) In terms of parts by mass, 6-11 parts of hydroxypropyl-β-cyclodextrin, 6-11 parts of Snaketodon grape extract, 0.01-0.05 parts of hyaluronic acid, and 8-12 parts of polyol moisturizers Mix with 0.1-0.5 parts of thickener, add water, heat to 65°C-80°C, and obtain the water phase after homogenization;

c)将步骤b)水相降温至40℃~50℃,加入步骤a)油相和3~5份Vc粉,再在真空环境下均质,得到美白淡斑化妆品;c) cooling the water phase in step b) to 40°C to 50°C, adding the oil phase in step a) and 3 to 5 parts of Vc powder, and then homogenizing in a vacuum environment to obtain a whitening and lightening cosmetic;

其中,所述基础油为乳木果油和荷荷巴油的混合物。Wherein, the base oil is a mixture of shea butter and jojoba oil.

本发明中,步骤a)均质的时间为5min~15min,步骤b)均质的时间为5min~10min,步骤c)均质的时间为5min~15min。In the present invention, the time for homogenization in step a) is 5 min to 15 min, the time for homogenization in step b) is 5 min to 10 min, and the time for homogenization in step c) is 5 min to 15 min.

步骤c)在真空环境下均质之后,得到美白淡斑化妆品之前,还包括:过滤。Step c) after homogenizing in a vacuum environment and before obtaining the whitening and blemish-reducing cosmetic, further includes: filtering.

本发明中,步骤a)具体为:In the present invention, step a) is specifically:

以质量份计,将7~13份基础油和4~7份植物乳化剂混合后加热至75℃,再加入0.2~0.8份防腐剂,均质后得到油相。In terms of parts by mass, 7-13 parts of base oil and 4-7 parts of vegetable emulsifier are mixed, heated to 75° C., and then 0.2-0.8 parts of preservative are added, and the oil phase is obtained after homogenization.

步骤b)具体为:Step b) is specifically:

以质量份计,将6~11份羟丙基-β-环糊精、6~11份显齿蛇葡萄提取物、0.01~0.05份透明质酸、8~12份多元醇类保湿剂和0.1~0.5份增稠剂混合后加水,加热至70℃,均质后得到水相。In terms of parts by mass, 6-11 parts of hydroxypropyl-β-cyclodextrin, 6-11 parts of Snaketodon grape extract, 0.01-0.05 parts of hyaluronic acid, 8-12 parts of polyhydric alcohol moisturizing agent and 0.1 ~0.5 parts of thickener are mixed and then added with water, heated to 70°C, homogenized to obtain a water phase.

步骤c)具体为:Step c) is specifically:

将步骤b)水相降温至40℃~50℃,加入步骤a)油相和3~5份Vc粉的混合液,再在真空环境下均质,得到美白淡斑化妆品。Cooling the water phase in step b) to 40°C to 50°C, adding the mixed solution of the oil phase in step a) and 3 to 5 parts of Vc powder, and then homogenizing in a vacuum environment to obtain a whitening and lightening cosmetic.

本发明美白淡斑化妆品的制备方法简单,易于工业生产。The preparation method of the whitening and lightening cosmetics of the present invention is simple and easy for industrial production.

为了进一步理解本发明,下面结合具体实施例对本发明进行详细阐述。In order to further understand the present invention, the present invention will be described in detail below in conjunction with specific examples.

实施例1Example 1

本实施例美白淡斑乳以重量份计,由以下组分制成:基础油10份、羟丙基-β-环糊精6份、显齿蛇葡萄提取物8份、植物乳化剂4份、透明质酸0.01份、Vc粉3份、多元醇类保湿剂9份、增稠剂0.1份、防腐剂0.2份和水59.69份。In this example, the whitening and blemish-reducing milk is made up of the following components in parts by weight: 10 parts of base oil, 6 parts of hydroxypropyl-β-cyclodextrin, 8 parts of Snake dentata grape extract, and 4 parts of plant emulsifier , 0.01 part of hyaluronic acid, 3 parts of Vc powder, 9 parts of polyol moisturizer, 0.1 part of thickener, 0.2 part of preservative and 59.69 parts of water.

本实施例美白淡斑乳的制备方法,包括以下步骤:The preparation method of the whitening cream of this embodiment comprises the following steps:

1)以质量份计,将10份基础油和4份植物乳化剂混合后加热至70℃,在搅拌条件下再加入0.2份防腐剂,搅拌均质10min后得到油相;1) In parts by mass, mix 10 parts of base oil and 4 parts of vegetable emulsifier, heat to 70°C, add 0.2 parts of preservative under stirring condition, stir and homogenize for 10 minutes to obtain the oil phase;

2)以质量份计,将6份羟丙基-β-环糊精、8份显齿蛇葡萄提取物、0.01份透明质酸、9份多元醇类保湿剂和0.1份增稠剂与水混合后加热至70℃,均质8min后得到水相;2) In terms of parts by mass, mix 6 parts of hydroxypropyl-β-cyclodextrin, 8 parts of dentata grape extract, 0.01 part of hyaluronic acid, 9 parts of polyhydric alcohol moisturizing agent and 0.1 part of thickener with water After mixing, heat to 70°C and homogenize for 8 minutes to obtain the water phase;

3)将步骤2)水相降温至45℃,加入步骤1)油相和3份Vc粉,再在真空环境下搅拌均质10min,过滤,得到美白淡斑乳。3) Cool the water phase in step 2) to 45°C, add the oil phase in step 1) and 3 parts of Vc powder, stir and homogenize in a vacuum environment for 10 minutes, and filter to obtain whitening and lightening milk.

实施例2Example 2

本实施例美白淡斑乳以重量份计,由以下组分制成:基础油13份、羟丙基-β-环糊精11份、显齿蛇葡萄提取物11份、植物乳化剂7份、透明质酸0.05份、Vc粉5份、多元醇类保湿剂11份、增稠剂0.5份、防腐剂0.8份和水40.65份。In this example, the whitening and blemish-reducing milk is made up of the following components in parts by weight: 13 parts of base oil, 11 parts of hydroxypropyl-β-cyclodextrin, 11 parts of Snake Grape Extract, and 7 parts of plant emulsifier , 0.05 parts of hyaluronic acid, 5 parts of Vc powder, 11 parts of polyol moisturizing agent, 0.5 part of thickener, 0.8 part of preservative and 40.65 parts of water.

本实施例美白淡斑乳的制备方法,包括以下步骤:The preparation method of the whitening cream of this embodiment comprises the following steps:

1)以质量份计,将13份基础油和7份植物乳化剂混合后加热至63℃,在搅拌条件下再加入0.8份防腐剂,搅拌均质5min后得到油相;1) In parts by mass, mix 13 parts of base oil and 7 parts of vegetable emulsifier, heat to 63°C, add 0.8 parts of preservative under stirring condition, stir and homogenize for 5 minutes to obtain the oil phase;

2)以质量份计,将11份羟丙基-β-环糊精、11份显齿蛇葡萄提取物、0.05份透明质酸、11份多元醇类保湿剂和0.5份增稠剂与水混合后加热至65℃,均质5min后得到水相;2) In terms of parts by mass, mix 11 parts of hydroxypropyl-β-cyclodextrin, 11 parts of Snake dentata extract, 0.05 part of hyaluronic acid, 11 parts of polyol moisturizing agent and 0.5 part of thickener with water After mixing, heat to 65°C and homogenize for 5 minutes to obtain the water phase;

3)将步骤2)水相降温至40℃,加入步骤1)油相和5份Vc粉,再在真空环境下搅拌均质5min,过滤,得到美白淡斑乳。3) Cool the water phase in step 2) to 40°C, add the oil phase in step 1) and 5 parts of Vc powder, stir and homogenize in a vacuum environment for 5 minutes, and filter to obtain whitening and spot-reducing milk.

实施例3Example 3

本实施例美白淡斑乳以重量份计,由以下组分制成:基础油11份、羟丙基-β-环糊精8份、显齿蛇葡萄提取物8份、植物乳化剂5份、透明质酸0.03份、Vc粉4份、多元醇类保湿剂10份、增稠剂0.3份、防腐剂0.5份和水48.17份。In this example, the whitening and blemish-reducing milk is made up of the following components in parts by weight: 11 parts of base oil, 8 parts of hydroxypropyl-β-cyclodextrin, 8 parts of Snake dentata grape extract, and 5 parts of plant emulsifier , 0.03 parts of hyaluronic acid, 4 parts of Vc powder, 10 parts of polyol moisturizer, 0.3 part of thickener, 0.5 part of preservative and 48.17 parts of water.

本实施例美白淡斑乳的制备方法,包括以下步骤:The preparation method of the whitening cream of this embodiment comprises the following steps:

1)以质量份计,将11份基础油和5份植物乳化剂混合后加热至63℃,在搅拌条件下再加入0.5份防腐剂,搅拌均质5min后得到油相;1) In parts by mass, mix 11 parts of base oil and 5 parts of vegetable emulsifier, heat to 63°C, add 0.5 parts of preservative under stirring condition, stir and homogenize for 5 minutes to obtain the oil phase;

2)以质量份计,将8份羟丙基-β-环糊精、8份显齿蛇葡萄提取物、0.03份透明质酸、10份多元醇类保湿剂和0.3份增稠剂与水混合后加热至65℃,均质5min后得到水相;2) In terms of parts by mass, mix 8 parts of hydroxypropyl-β-cyclodextrin, 8 parts of snakehead grape extract, 0.03 part of hyaluronic acid, 10 parts of polyhydric alcohol moisturizing agent and 0.3 part of thickener with water After mixing, heat to 65°C and homogenize for 5 minutes to obtain the water phase;

3)将步骤2)水相降温至40℃,加入步骤1)油相和4份Vc粉,再在真空环境下搅拌均质5min,过滤,得到美白淡斑乳。3) Cool the water phase in step 2) to 40°C, add the oil phase in step 1) and 4 parts of Vc powder, stir and homogenize in a vacuum environment for 5 minutes, and filter to obtain whitening and spot-lightening milk.

对比例1Comparative example 1

本对比例美白淡斑乳为熊果苷美白淡斑乳,熊果苷美白淡斑乳以重量份计,由以下组分制成:基础油13份、羟丙基-β-环糊精11份、熊果苷11份、植物乳化剂7份、透明质酸0.05份、Vc粉5份、多元醇类保湿剂11份、增稠剂0.5份、防腐剂0.8份和水40.65份。The whitening and lightening milk of this comparative example is arbutin whitening and lightening milk, and the arbutin whitening and lightening milk is made of the following components in parts by weight: 13 parts of base oil, 11 parts of hydroxypropyl-β-cyclodextrin 11 parts of arbutin, 7 parts of plant emulsifier, 0.05 parts of hyaluronic acid, 5 parts of Vc powder, 11 parts of polyol moisturizer, 0.5 part of thickener, 0.8 part of preservative and 40.65 parts of water.

本实施例熊果苷美白淡斑乳液的制备方法,包括以下步骤:The preparation method of the arbutin whitening and spot-lightening emulsion of this embodiment comprises the following steps:

1)以质量份计,将13份基础油和7份植物乳化剂混合后加热至63℃,在搅拌条件下再加入0.8份防腐剂,搅拌均质5min后得到油相;1) In parts by mass, mix 13 parts of base oil and 7 parts of vegetable emulsifier, heat to 63°C, add 0.8 parts of preservative under stirring condition, stir and homogenize for 5 minutes to obtain the oil phase;

2)以质量份计,将11份羟丙基-β-环糊精、11份熊果苷、0.05份透明质酸、11份多元醇类保湿剂和0.5份增稠剂与水混合后加热至65℃,均质5min后得到水相;2) In parts by mass, mix 11 parts of hydroxypropyl-β-cyclodextrin, 11 parts of arbutin, 0.05 part of hyaluronic acid, 11 parts of polyol moisturizing agent and 0.5 part of thickener with water and heat to 65°C, homogenized for 5 minutes to obtain the aqueous phase;

3)将步骤2)水相降温至40℃,加入步骤1)油相和5份Vc粉,再在真空环境下搅拌均质5min,过滤,得到熊果苷美白淡斑乳。3) Cool the water phase in step 2) to 40°C, add the oil phase in step 1) and 5 parts of Vc powder, stir and homogenize in a vacuum environment for 5 minutes, and filter to obtain arbutin whitening milk.

对比例2Comparative example 2

本对比例美白淡斑乳为曲酸美白淡斑乳,曲酸美白淡斑乳以重量份计,由以下组分制成:基础油13份、羟丙基-β-环糊精11份、曲酸11份、植物乳化剂7份、透明质酸0.05份、Vc粉5份、多元醇类保湿剂11份、增稠剂0.5份、防腐剂0.8份和水40.65份。This comparative whitening cream is kojic acid whitening cream, and the kojic acid whitening cream is made of the following components in parts by weight: 13 parts of base oil, 11 parts of hydroxypropyl-β-cyclodextrin, 11 parts of kojic acid, 7 parts of plant emulsifier, 0.05 part of hyaluronic acid, 5 parts of Vc powder, 11 parts of polyol moisturizer, 0.5 part of thickener, 0.8 part of preservative and 40.65 parts of water.

本实施例曲酸美白淡斑乳液的制备方法,包括以下步骤:The preparation method of the kojic acid whitening and spot-lightening emulsion of this embodiment comprises the following steps:

1)以质量份计,将13份基础油和7份植物乳化剂混合后加热至63℃,在搅拌条件下再加入0.8份防腐剂,搅拌均质5min后得到油相;1) In parts by mass, mix 13 parts of base oil and 7 parts of vegetable emulsifier, heat to 63°C, add 0.8 parts of preservative under stirring condition, stir and homogenize for 5 minutes to obtain the oil phase;

2)以质量份计,将11份羟丙基-β-环糊精、11份曲酸、0.05份透明质酸、11份多元醇类保湿剂和0.5份增稠剂与水混合后加热至65℃,均质5min后得到水相;2) In terms of parts by mass, mix 11 parts of hydroxypropyl-β-cyclodextrin, 11 parts of kojic acid, 0.05 part of hyaluronic acid, 11 parts of polyol moisturizing agent and 0.5 part of thickener with water and heat to 65°C, after homogenizing for 5 minutes, the aqueous phase was obtained;

3)将步骤2)水相降温至40℃,加入步骤1)油相和5份Vc粉,再在真空环境下搅拌均质5min,过滤,得到曲酸美白淡斑乳。3) Cool the water phase in step 2) to 40°C, add the oil phase in step 1) and 5 parts of Vc powder, stir and homogenize in a vacuum environment for 5 minutes, and filter to obtain kojic acid whitening milk.

对比例3Comparative example 3

本对比例美白淡斑乳为显齿蛇葡萄美白淡斑乳,以重量份计,由以下组分制成:基础油13份、显齿蛇葡萄提取物11份、植物乳化剂7份、透明质酸0.05份、Vc粉5份、多元醇类保湿剂11份、增稠剂0.5份、防腐剂0.8份和水51.65份。The whitening and spot-reducing milk of this comparative example is the whitening and spot-reducing milk of snake-toothed snake grape, which is made of the following components in parts by weight: 13 parts of base oil, 11 parts of snake-toothed grape extract, 7 parts of plant emulsifier, transparent 0.05 parts of hyaluronic acid, 5 parts of Vc powder, 11 parts of polyols moisturizing agent, 0.5 parts of thickener, 0.8 parts of preservative and 51.65 parts of water.

本实施例显齿蛇葡萄美白淡斑乳的制备方法,包括以下步骤:The preparation method of the tooth-snake grape whitening cream of this embodiment comprises the following steps:

1)以质量份计,将13份基础油和7份植物乳化剂混合后加热至63℃,在搅拌条件下再加入0.8份防腐剂,搅拌均质5min后得到油相;1) In parts by mass, mix 13 parts of base oil and 7 parts of vegetable emulsifier, heat to 63°C, add 0.8 parts of preservative under stirring condition, stir and homogenize for 5 minutes to obtain the oil phase;

2)以质量份计,将11份显齿蛇葡萄提取物、0.05份透明质酸、11份多元醇类保湿剂和0.5份增稠剂与水混合后加热至65℃,均质5min后得到水相;2) In terms of parts by mass, mix 11 parts of Snakedon grape extract, 0.05 part of hyaluronic acid, 11 parts of polyol moisturizer and 0.5 part of thickener with water, heat to 65°C, and homogenize for 5 minutes to obtain water box;

3)将步骤2)水相降温至45℃,加入步骤1)油相和5份Vc粉,再在真空环境下搅拌均质5min,过滤,得到显齿蛇葡萄美白淡斑乳。3) Cool the water phase in step 2) to 45°C, add the oil phase in step 1) and 5 parts of Vc powder, stir and homogenize in a vacuum environment for 5 minutes, and filter to obtain the whitening and spot-lightening milk of Snake dentata.

本发明中,传统的美白淡斑乳液和没有加入羟丙基-β-环糊精的显齿蛇葡萄淡斑乳液的美白效果和稳定性不如加了羟丙基-β-环糊精的美白淡斑乳液,实施例1~2制作的美白淡斑乳液更加天然,对人体无害且美白效果好的化妆品。In the present invention, the whitening effect and stability of the traditional whitening and spot-lightening emulsion and the whitening lotion without adding hydroxypropyl-β-cyclodextrin are not as good as those with the addition of hydroxypropyl-β-cyclodextrin Spot-lightening lotion, the whitening spot-lightening lotion made in Examples 1-2 is more natural, harmless to human body and cosmetics with good whitening effect.

以上所述仅是本发明的优选实施方式,应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above is only a preferred embodiment of the present invention, it should be pointed out that, for those of ordinary skill in the art, without departing from the principle of the present invention, some improvements and modifications can also be made, and these improvements and modifications can also be made. It should be regarded as the protection scope of the present invention.

Claims (10)

1.一种美白淡斑化妆品,其特征在于,以重量份计,由以下组分制成:基础油10~13份、羟丙基-β-环糊精6~11份、显齿蛇葡萄提取物6~11份、植物乳化剂4~7份、透明质酸0.01~0.05份、Vc粉3~5份、多元醇类保湿剂8~12份、增稠剂0.1~0.5份、防腐剂0.2~0.8份和水30~60份。1. A whitening and lightening cosmetic, characterized in that, in parts by weight, it is made of the following components: 10-13 parts of base oil, 6-11 parts of hydroxypropyl-β-cyclodextrin, 6-11 parts of extract, 4-7 parts of plant emulsifier, 0.01-0.05 parts of hyaluronic acid, 3-5 parts of Vc powder, 8-12 parts of polyol moisturizer, 0.1-0.5 part of thickener, preservative 0.2 to 0.8 parts and 30 to 60 parts of water. 2.根据权利要求1所述的美白淡斑化妆品,其特征在于,以重量份计,由以下组分制成:基础油10份、羟丙基-β-环糊精8份、显齿蛇葡萄提取物8份、植物乳化剂5份、透明质酸0.03份、Vc粉4份、多元醇类保湿剂10份、增稠剂0.3份、防腐剂0.5份和水53.67份。2. The whitening and lightening cosmetic according to claim 1, characterized in that, in parts by weight, it is made of the following components: 10 parts of base oil, 8 parts of hydroxypropyl-β-cyclodextrin, 8 parts of grape extract, 5 parts of plant emulsifier, 0.03 part of hyaluronic acid, 4 parts of Vc powder, 10 parts of polyol moisturizer, 0.3 part of thickener, 0.5 part of preservative and 53.67 parts of water. 3.根据权利要求1所述的美白淡斑化妆品,其特征在于,所述显齿蛇葡萄提取物中的二氢杨梅素含量为23.40wt%~40.66wt%。3 . The whitening and spot-reducing cosmetic according to claim 1 , characterized in that, the content of dihydromyricetin in the S. dentata extract is 23.40wt%-40.66wt%. 4.根据权利要求1所述的美白淡斑化妆品,其特征在于,所述基础油为乳木果油和荷荷巴油的混合物;4. The whitening and spot-reducing cosmetic according to claim 1, wherein the base oil is a mixture of shea butter and jojoba oil; 所述乳木果油与所述荷荷巴油的质量比为3~8:4~7。The mass ratio of the shea butter to the jojoba oil is 3-8:4-7. 5.根据权利要求1所述的美白淡斑化妆品,其特征在于,所述多元醇类保湿剂为丙三醇和丁二醇的混合物;5. The whitening and spot-reducing cosmetic according to claim 1, wherein the polyhydric alcohol moisturizing agent is a mixture of glycerol and butanediol; 所述丙三醇和所述丁二醇的质量比为3~8:7~12。The mass ratio of the glycerol to the butanediol is 3-8:7-12. 6.根据权利要求1所述的美白淡斑化妆品,其特征在于,所述显齿蛇葡萄提取物由以下方法制得:6. The whitening and spot-reducing cosmetic according to claim 1, characterized in that, the extract of the snake grape is prepared by the following method: 将显齿蛇葡萄幼嫩茎叶加入水中,煮沸,用乙酸乙酯萃取后除去多糖,得到所述显齿蛇葡萄提取物。Adding the young stems and leaves of Grape dentata into water, boiling, extracting with ethyl acetate and removing polysaccharides, so as to obtain the extract of Grape dentatus. 7.一种美白淡斑化妆品的制备方法,其特征在于,包括以下步骤:7. A preparation method for whitening and lightening cosmetics, comprising the following steps: a)以质量份计,将7~13份基础油和4~7份植物乳化剂混合后加热至63℃~80℃,再加入0.2~0.8份防腐剂,均质后得到油相;a) In parts by mass, mix 7-13 parts of base oil and 4-7 parts of vegetable emulsifier, heat to 63°C-80°C, add 0.2-0.8 parts of preservative, and homogenize to obtain an oil phase; b)以质量份计,将6~11份羟丙基-β-环糊精、6~11份显齿蛇葡萄提取物、0.01~0.05份透明质酸、8~12份多元醇类保湿剂和0.1~0.5份增稠剂混合后加水,加热至65℃~80℃,均质后得到水相;b) In terms of parts by mass, 6-11 parts of hydroxypropyl-β-cyclodextrin, 6-11 parts of Snaketodon grape extract, 0.01-0.05 parts of hyaluronic acid, and 8-12 parts of polyol moisturizers Mix with 0.1-0.5 parts of thickener, add water, heat to 65°C-80°C, and obtain the water phase after homogenization; c)将步骤b)所述水相降温至40℃~50℃,加入步骤a)所述油相和3~5份Vc粉,再在真空环境下均质,得到美白淡斑化妆品;c) cooling the water phase in step b) to 40°C to 50°C, adding the oil phase in step a) and 3 to 5 parts of Vc powder, and then homogenizing in a vacuum environment to obtain a whitening and lightening cosmetic; 其中,所述基础油为乳木果油和荷荷巴油的混合物。Wherein, the base oil is a mixture of shea butter and jojoba oil. 8.根据权利要求7所述的制备方法,其特征在于,所述步骤a)具体为:8. the preparation method according to claim 7, is characterized in that, described step a) is specifically: 以质量份计,将7~13份所述基础油和4~7份所述植物乳化剂混合后加热至75℃,再加入0.2~0.8份所述防腐剂,均质后得到所述油相。In parts by mass, mix 7-13 parts of the base oil and 4-7 parts of the vegetable emulsifier, heat to 75°C, add 0.2-0.8 parts of the preservative, and homogenize to obtain the oil phase . 9.根据权利要求7所述的制备方法,其特征在于,所述步骤b)具体为:9. the preparation method according to claim 7, is characterized in that, described step b) is specifically: 以质量份计,将6~11份所述羟丙基-β-环糊精、6~11份所述显齿蛇葡萄提取物、0.01~0.05份所述透明质酸、8~12份所述多元醇类保湿剂和0.1~0.5份所述增稠剂混合后加水,加热至70℃,均质后得到所述水相。In parts by mass, 6 to 11 parts of the hydroxypropyl-β-cyclodextrin, 6 to 11 parts of the extract of the snake grape, 0.01 to 0.05 parts of the hyaluronic acid, 8 to 12 parts of the The polyhydric alcohol moisturizing agent and 0.1-0.5 part of the thickener are mixed, then water is added, heated to 70° C., and the water phase is obtained after homogenization. 10.根据权利要求7所述的制备方法,其特征在于,所述步骤c)具体为:10. The preparation method according to claim 7, characterized in that, said step c) is specifically: 将步骤b)所述水相降温至40℃~50℃,加入步骤a)所述油相和3~5份所述Vc粉的混合液,再在真空环境下均质,得到所述美白淡斑化妆品。Cool the water phase in step b) to 40°C-50°C, add the oil phase in step a) and 3-5 parts of the Vc powder mixture, and then homogenize in a vacuum environment to obtain the whitening light spot cosmetics.
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Cited By (6)

* Cited by examiner, † Cited by third party
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CN109288760A (en) * 2018-11-27 2019-02-01 广东中测食品化妆品安全评价中心有限公司 A kind of plant essence face cream and preparation method thereof
CN111803416A (en) * 2020-07-17 2020-10-23 堇色生物科技(中山)有限责任公司 Anti-aging cream containing ampelopsis grossedentata and preparation method thereof
CN113230198A (en) * 2021-06-02 2021-08-10 上海佩威化妆品有限公司 Anti-wrinkle anti-aging freeze-dried essence and preparation method thereof
CN115501151A (en) * 2022-10-10 2022-12-23 广东工业大学 Tearable potato soft mask powder with whitening effect and preparation method thereof
CN115501151B (en) * 2022-10-10 2024-01-16 广东工业大学 Tear-off potato soft film powder with whitening effect and preparation method thereof
CN119015172A (en) * 2024-08-21 2024-11-26 佛山九韵生物科技有限公司 A whitening facial cream containing cyclodextrin and preparation method thereof

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Application publication date: 20181016