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CN108619395A - A kind of biochip essential oil drug paste of antihypertensive - Google Patents

A kind of biochip essential oil drug paste of antihypertensive Download PDF

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Publication number
CN108619395A
CN108619395A CN201810390735.8A CN201810390735A CN108619395A CN 108619395 A CN108619395 A CN 108619395A CN 201810390735 A CN201810390735 A CN 201810390735A CN 108619395 A CN108619395 A CN 108619395A
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Prior art keywords
essential oil
absorbent cotton
biochip
parts
drug
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Withdrawn
Application number
CN201810390735.8A
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Chinese (zh)
Inventor
张永才
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Individual
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Individual
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Priority to CN201810390735.8A priority Critical patent/CN108619395A/en
Publication of CN108619395A publication Critical patent/CN108619395A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

A kind of biochip essential oil drug paste of antihypertensive, is related to a kind of drug paste, the drug paste produces essential oil first:Choose 15 parts of the Chinese medicine fruit of medicinal cornel, 15 parts of chrysanthemum, 10 parts of the flower bud of lily magnolia, 10 parts of Rhizoma Gastrodiae, 30 parts of semen brassicae, arisaema cum bile, rhizoma atractylodis, each 20 parts of Rhizoma Chuanxiong, 60 parts of olive oil;Essential oil of traditional Chinese medicine is made in above-mentioned material;Ringent mesh bag(5), inside it is installed with biochip(6), mesh bag(5)One side on be formed with two symmetrical viscose tops(2);Viscose top(2)It is equipped with drug paste on one side(3)And absorbent cotton(4);Absorbent cotton(4)It is attached to drug paste(3)On;Absorbent cotton(4)For circle;Viscose top(2)On sticked paper membrane(1), the paper membrane 1 applied on 4 surface of absorbent cotton is opened, above-mentioned essential oil is sprayed on absorbent cotton 4, absorbent cotton 4 is directed at the acupuncture point on body, as nei guan point, Quchi acupoint, point Hegu stick 24 hours daily.Biochip is placed at needed by human body drug target treatment by the present invention, realizes the maximization of symptomatic treatment hypertension curative effect.

Description

A kind of biochip essential oil drug paste of antihypertensive
Technical field
The present invention relates to a kind of Traditional Chinese medicine plasters of auxiliary treatment, more particularly to a kind of biochip essential oil medicine of antihypertensive Patch.
Background technology
Biochip is obvious in mechanism of drug action, and drug target finds that with mechanism of drug action research be biological core The field that chip technology is most widely used in medicament research and development.The institute in drug target is found and mechanism of drug action is studied The biochip used is primarily referred to as DNA chip.It can be whole to the interested gene of researcher or organism using DNA chips The gene expression of a genome is measured.It is drug to find and select suitable drug target in contemporary drug discovery process One of the key factor of the first step of exploitation and drug screening and drug controlled syntheses.Human body is a complicated network system System, the occurrence and development of disease necessarily involve all too many levels in network.The current cardiovascular and cerebrovascular for seriously threatening human health Disease, malignant tumour, senile dementia and some metabolic disturbance diseases are all multifactor effects as a result, tending not to sum up In the variation of single factors.
Acupoint application treatment patch disclosed in the prior art is prepared complicated, of high cost.And it is dumb to make per se with drug With.
It is relatively common method that hypertension, which is treated and alleviated using acupuncture point, be such as acupuncture, massage and other effects it will be evident that But percutaneous absorbtion traditional Chinese medicine ingredients, it can promote drug in the osmotic absorption process of organism skin surface as penetrating agent, increase The treatment means of the permeability of dosing object are more rare.Chinese medicine treatment for treatment hypertension, cardiovascular and cerebrovascular disease needs out The treatment means for sending out new, essential oil drug paste combine traditional acupoint therapy, receive extraordinary effect.
Invention content
The purpose of the present invention is to provide a kind of biochip essential oil drug pastes of antihypertensive.The drug paste is smart by traditional Chinese medicine Essential oil is made in China, drops on absorbent cotton, is discharged using the drug effect essential oil in biochip activation absorbent cotton, to realize that drug target is controlled Treat the effect of hypertension.
The purpose of the present invention is what is be achieved through the following technical solutions:
A kind of biochip essential oil drug paste of antihypertensive, the biochip essential oil drug paste of the treatment hypertension, is produced first Essential oil:Choose 15 parts of the Chinese medicine fruit of medicinal cornel, 15 parts of chrysanthemum, 10 parts of the flower bud of lily magnolia, 10 parts of Rhizoma Gastrodiae, 30 parts of semen brassicae, arisaema cum bile, rhizoma atractylodis, Rhizoma Chuanxiong Each 20 parts, 60 parts of olive oil;Essential oil of traditional Chinese medicine is made in above-mentioned material;Ringent mesh bag is inside installed with biochip, mesh bag One side on be formed with two symmetrical viscose tops;Viscose top is equipped with drug paste and absorbent cotton on one side;Absorbent cotton is attached in drug paste;Absorbent cotton is It is round;Paper membrane has been sticked on viscose top, and the paper membrane applied on 4 surface of absorbent cotton is opened, above-mentioned essential oil is sprayed on absorbent cotton, by medicine Cotton is directed at the acupuncture point on body, as nei guan point, Quchi acupoint, point Hegu stick 2-4 hours daily.
A kind of biochip essential oil drug paste of antihypertensive, the viscose top of the biochip patch surrounding that is laid in Biological paste is firmly pasted onto at body acupuncture point;So that drug effect is discharged, choose the acupuncture point of sick body or pain spot stick after can be more Secondary oil dripping reaches the therapeutic effect of physical therapy by the drug dredging the channel of infiltration, alleviation hypertension.
Advantages of the present invention is with effect:
1. essential oil is made in traditional Chinese medicine essence by drug paste of the present invention, drop on absorbent cotton, utilizes the medicine in biochip activation absorbent cotton Essential oil release is imitated, biochip is placed at needed by human body drug target treatment, realizes the maximization of curative effect, which is easy to general And it is practical.
It is dropped on absorbent cotton 2. drug effect essential oil acupoint plaster of the present invention is a kind of essential oil of traditional Chinese medicine, using the viscose glue of auxiliary setting Item,
The settings such as mesh bag, are pasted on human acupoint, it is lasting can be allowed to pharmacology according to the multiple oil dripping Reusability of the state of an illness.
3. the essential oil of the present invention is reasonable, essential oil preparation method is simple and practical, the Chinese medicine essence of extraction, swashs in conjunction with biochip Drug effect living, keeps the mechanism of drug action for the treatment of hypertension obvious, and drug target curative effect protrudes.
Description of the drawings
Fig. 1 is the overall structure diagram of the present invention.
In figure:Paper membrane 1, viscose top 2, drug paste 3, absorbent cotton 4, mesh bag 5, biochip 6.
Specific implementation mode
The present invention is described in detail for illustrated embodiment below in conjunction with the accompanying drawings.
Essential oil is produced first:Choose 15 grams of the Chinese medicine fruit of medicinal cornel, 15 grams of chrysanthemum, 10 grams of the flower bud of lily magnolia, 10 grams of Rhizoma Gastrodiae, 30 grams of semen brassicae, Each 20 grams of arisaema cum bile, rhizoma atractylodis, Rhizoma Chuanxiong, 60 grams of olive oil.Above-mentioned material is ground into 200 mesh smalls, is placed in container in proportion, It is submerged with olive oil, is then slowly heated to 80-95 DEG C, so that solution is extracted the extract of material, material paste is by squeezing After press filtration processing, then through evaporation process;Repeatedly the above process obtains medical treatment the essential oil of traditional Chinese medicine of hypertension repeatedly, and bottling is for use i.e. It can.
A kind of biochip drug paste of the present invention includes paper membrane 1, viscose top 2, drug paste 3, absorbent cotton 4, mesh bag 5, biochip 6.
The opening-like mesh bag 5 of present invention one side, is inside installed with biochip 6, be formed in the one side of mesh bag 5 two it is right The viscose top 2 of title;Viscose top 2 is equipped with drug paste 3 and absorbent cotton 4 on one side;Absorbent cotton 4 is attached in drug paste 3;Absorbent cotton 4 is circle.Viscose top Paper membrane 1 has been sticked on 2.Opening-like mesh bag 5 on one side is inside installed with biochip 6, four sides is formed in the one side of mesh bag 5 Viscose top 2.
Opening-like mesh bag 5 on one side is inside installed with biochip 6, paper has been sticked on a face viscose top 2 of mesh bag 5 Film 1.
The present invention, which selects, is suitable for the biochip that surface sticks, and places it in mesh bag 5, mesh bag 5 is selected medical thin fabric , symmetrical sticked equipped with two in the side of mesh bag 5 is equipped with viscose top 2 with viscose top 2 or surrounding, to ensure the jail pasted Solidity;Mesh bag 5 sets drug paste 3 on the side with viscose top 2, and the upper surface of drug paste 3 is deposited with absorbent cotton 4;Drug paste 3 is medical thin cloth, Less than mesh bag 5, a round absorbent cotton 4 is pasted at the center of drug paste 3;Also drug paste 3, absorbent cotton 4 can be encapsulated in other packaging bag, The mesh bag 5 packed with biochip 6 packs use respectively, can reuse the mesh bag 5 of the packaging of biochip 6 in this way, meanwhile, Drug paste 3, absorbent cotton 4 can also be designed to product not of uniform size, targetedly select.In use, will apply on 4 surface of absorbent cotton Paper membrane 1 open, essential oil is sprayed on absorbent cotton 4, by absorbent cotton 4 be aligned body on acupuncture point, such as nei guan point, Quchi acupoint, point Hegu It is relatively good that 2-4 hours secondary buck effects are sticked daily, are sticked.The viscose top 2 of the biochip that is laid in patch surrounding will give birth to Object patch is firmly pasted onto at body acupuncture point;Drug effect is set to be discharged.The acupuncture point of selection sick body or pain spot can repeatedly drip after sticking Oil by the drug dredging the channel of infiltration, alleviates hypertension, reaches the therapeutic effect of physical therapy.

Claims (2)

1. a kind of biochip essential oil drug paste of antihypertensive, which is characterized in that the biochip essential oil drug paste includes treatment The biochip and essential oil drug paste of hypertension, produce essential oil first:Choose 15 parts of the Chinese medicine fruit of medicinal cornel, 15 parts of chrysanthemum, the flower bud of lily magnolia 10 part, day 10 parts of fiber crops, 30 parts of semen brassicae, arisaema cum bile, rhizoma atractylodis, each 20 parts of Rhizoma Chuanxiong, 60 parts of olive oil;Essential oil of traditional Chinese medicine is made in above-mentioned material;It opens The mesh bag of mouth shape(5), inside it is installed with biochip(6), mesh bag(5)One side on be formed with two symmetrical viscose tops(2);It is viscous Adhesive tape(2)It is equipped with drug paste on one side(3)And absorbent cotton(4);Absorbent cotton(4)It is attached to drug paste(3)On;Absorbent cotton(4)For circle;Viscose top (2)On sticked paper membrane(1), the paper membrane 1 applied on 4 surface of absorbent cotton is opened, above-mentioned essential oil is sprayed on absorbent cotton 4, by absorbent cotton 4 It is directed at the acupuncture point on body, as nei guan point, Quchi acupoint, point Hegu stick 2-4 hours daily.
2. a kind of biochip essential oil drug paste of antihypertensive according to claim 1, which is characterized in that described to be laid in Biochip pastes the viscose top of surrounding(2)Biological paste is firmly pasted onto at body acupuncture point;So that drug effect is discharged, chooses disease The acupuncture point of body or pain spot stick after can multiple oil dripping, by the drug dredging the channel of infiltration, alleviate hypertension reach controlling for physical therapy Therapeutic effect.
CN201810390735.8A 2018-04-27 2018-04-27 A kind of biochip essential oil drug paste of antihypertensive Withdrawn CN108619395A (en)

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CN201810390735.8A CN108619395A (en) 2018-04-27 2018-04-27 A kind of biochip essential oil drug paste of antihypertensive

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113058007A (en) * 2021-03-03 2021-07-02 杭州世子合德生物科技有限公司 A Chinese herbal preparation with health promoting effect, and its preparation method
CN115969825A (en) * 2023-03-08 2023-04-18 黑龙江迪龙制药有限公司 Metoprolol-containing sustained-release pharmaceutical composition and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1552416A (en) * 2003-06-03 2004-12-08 天津天士力制药股份有限公司 Medicine composition application for preparing hypertension medicine
CN101984987A (en) * 2010-11-01 2011-03-16 黄品月 Traditional Chinese medicine formula for reducing hypertension
CN102526692A (en) * 2012-02-27 2012-07-04 张克杰 Chinese medicine method for curing fatty liver and erosion symptom and traditional Chinese medicine composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1552416A (en) * 2003-06-03 2004-12-08 天津天士力制药股份有限公司 Medicine composition application for preparing hypertension medicine
CN101984987A (en) * 2010-11-01 2011-03-16 黄品月 Traditional Chinese medicine formula for reducing hypertension
CN102526692A (en) * 2012-02-27 2012-07-04 张克杰 Chinese medicine method for curing fatty liver and erosion symptom and traditional Chinese medicine composition

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113058007A (en) * 2021-03-03 2021-07-02 杭州世子合德生物科技有限公司 A Chinese herbal preparation with health promoting effect, and its preparation method
CN115969825A (en) * 2023-03-08 2023-04-18 黑龙江迪龙制药有限公司 Metoprolol-containing sustained-release pharmaceutical composition and preparation method thereof

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Application publication date: 20181009

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