CN108562459A - A kind of sampler of bioreactor - Google Patents
A kind of sampler of bioreactor Download PDFInfo
- Publication number
- CN108562459A CN108562459A CN201810228079.1A CN201810228079A CN108562459A CN 108562459 A CN108562459 A CN 108562459A CN 201810228079 A CN201810228079 A CN 201810228079A CN 108562459 A CN108562459 A CN 108562459A
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- bioreactor
- driving
- motor
- rack
- driving belt
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- 238000005070 sampling Methods 0.000 claims abstract description 41
- 238000003466 welding Methods 0.000 claims description 38
- 230000005540 biological transmission Effects 0.000 claims description 29
- 238000005520 cutting process Methods 0.000 claims description 13
- 230000005611 electricity Effects 0.000 claims description 13
- 239000000203 mixture Substances 0.000 claims description 13
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 7
- 230000001464 adherent effect Effects 0.000 claims description 5
- 239000003292 glue Substances 0.000 claims description 5
- 238000000465 moulding Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 abstract description 8
- 238000004064 recycling Methods 0.000 abstract description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
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- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of samplers of bioreactor, its structure includes bioreactor, digital display screen, pressure gauge, control panel, bottom block, Autosampler, supporting rack, it is detained cylinder, connecting tube, sample cell, bioreactor is set to bottom block upper right, digital display screen is embedded in bioreactor front surface top, pressure gauge is set to below bioreactor front surface, control panel is embedded in below bioreactor front surface and is located at pressure gauge left side side, Autosampler is set to bottom block upper left and is connected by connection flexible pipe and bioreactor perforation, supporting rack is uniformly equidistantly set to above Autosampler and vertical connection is engaged in its lower end with Autosampler upper surface by screw thread.The present invention is by being equipped with Autosampler, it can automatically begin to sample after bioreactor completes reaction, kinetic energy when sampling is carried out recycling simultaneously to be converted into electric energy and provide electric energy for warning light, effectively enhances the automation performance of the sampler of bioreactor, more hommization.
Description
Technical field
The present invention is a kind of sampler of bioreactor, belongs to bioreactor field.
Background technology
Bioreactor refers to any manufacture for providing bioactivity environment or engineering equipment.In one case, biological
Reactor, which is one, to carry out being related to the chemical process that biology or biochemical activity substance are come out by specific biological production
Container.This process can aerobic progress or anaerobic progress.These bioreactors are usually cylindrical, and volume is from several
It is raised to several cubic metres to differ, often be made of stainless steel.
But sampler the degree of automation of the bioreactor of the prior art is relatively low, increases the work of staff
Amount.
Invention content
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of sampler of bioreactor, with solution
Certainly sampler the degree of automation of the bioreactor of the prior art is relatively low, increases the defect of the workload of staff.
To achieve the goals above, the present invention is to realize by the following technical solutions：A kind of bioreactor takes
Sampling device, structure include bioreactor, digital display screen, pressure gauge, control panel, bottom block, Autosampler, support
Frame is detained cylinder, connecting tube, sample cell, and the bioreactor is set to bottom block upper right, and the digital display screen is embedded in
Bioreactor front surface top, the pressure gauge are set to below bioreactor front surface, and the control panel is embedded in life
Below object reactor front surface and it is located at pressure gauge left side side, the Autosampler is set to bottom block upper left and passes through company
The perforation of hose and bioreactor is connect to connect, support frame as described above be uniformly equidistantly set to above Autosampler and its lower end with it is automatic
Vertical connection is engaged in sampler upper surface by screw thread, and the delay cylinder is set to inside supporting rack and passes through spiral shell with supporting rack upper end
Line engages vertical connection, and the connecting tube lower end is connected with the perpendicular shape perforation of cylinder is detained, the connecting tube upper end and sample cell
Perforation connection, the Autosampler by electromagnetic drive mechanism, traction connect motor structure, motor-driven mechanism, push-and-pull sampling mechanism,
Laddertron, one-way flow mechanism, kinetic energy converting electrical energy mechanism, sampling warning light, closure composition, the electromagnetic drive mechanism
It being electrically connected set on the closure upper right corner and with bioreactor, the traction connects motor structure below electromagnetic drive mechanism,
The traction connects motor structure and is electrically connected with motor-driven mechanism, the push-and-pull sampling mechanism set on motor-driven mechanism left side side and
It is engaged and is flexibly connected by driving belt, the laddertron is obliquely set to inside closure and passes through electricity with closure
Weldering perforation connection, the one-way flow mechanism set there are two and are respectively arranged on inside the corner of laddertron, the kinetic energy conversion
Electric energy mechanism is set to above push-and-pull sampling mechanism and is engaged by driving belt and is flexibly connected, and the sampling warning light is embedded in envelope
Close case surface and be electrically connected with kinetic energy converting electrical energy mechanism, the cylinder structure of the closure and with bottom block upper surface
It is connected by electric welding.
Further, the electromagnetic drive mechanism by electromagnet, swing rod, fixed plate, armature block, upper rack, the first spring,
Spur gear, lower rack, second spring composition, the electromagnet are embedded in closure upper right corner inner wall, and the swing rod is set to electricity
It magnet lower left and is connect by articulate with fixed plate, the armature block, which is set to swing rod upper end and passes through glue bonding, to be connected
It connects, the lower end of the swing rod is connect with upper rack by articulate, and the upper rack is set to above spur gear and passes through the gear teeth
Engagement flexible connection, first spring are set to upper rack right side side and are connected by electric welding, and the lower rack is set to commutating tooth
It is flexibly connected below wheel and by gear teeth meshing, the second spring is set to rack left side side and is connected by electric welding.
Further, the traction connects motor structure by wheel carrier, traction swing rod, hinging fulcrum, lantern ring, camber line bar, third bullet
Spring, traction rope, fixed pulley, upright sliding bar, lifting saddle, the 4th spring, limited block, dynamic electric end composition, the traction swing rod are in
Vertical shape is set among wheel carrier and is flexibly connected by hinging fulcrum, and the set is located on traction swing rod lower end and in one chemical conversion
Type structure, for the lantern ring embedded in camber line rod outer surface and being gap-matched, the third spring is set to lantern ring right side side and logical
It crosses electric welding to be connected, described traction rope one end is intertwined and connected with traction swing rod upper end, and the traction rope other end bypasses fixed pulley
It is intertwined and connected with lifting saddle, the lifting saddle is placed on upright sliding bar outer surface and is gap-matched, the 4th spring
Set on lifting saddle below and by electric welding be connected, the limited block be set in upright sliding bar middle and lower sections and in upright sliding bar
In integrated molding structure, the dynamic electric end is set to lifting saddle left side side and is electrically connected with motor-driven mechanism.
Further, the motor-driven mechanism is passed by driving motor, motor cabinet, electrostatic end, the first driving belt, first
Moving gear, the second transmission gear, the second driving belt composition, the driving motor are set to above motor cabinet and are connected by being welded
It connects, the driving motor is connect by motor cabinet with closure spiral inner wall, and the electrostatic end is set to driving motor right side side
And rectify top positioned at dynamic electricity, first driving belt is set between driving motor, the first transmission gear and and driving motor
Power output shaft, the first transmission gear wheel shaft engagement flexible connection, second transmission gear be set to the first transmission gear
Left side side and be flexibly connected by gear teeth meshing, second driving belt be set to the second transmission gear, push-and-pull sampling mechanism it
Between and with the wheel shaft of the second driving belt, push and pull sampling mechanism central shaft engage flexible connection.
Further, the push-and-pull sampling mechanism is by rotating wheel, fixed frame, rotating sliding bar, push-and-pull block, connecting rod, cunning
Part, slide bar, spud pile, welding block, telescopic rod, elastic piece composition, the rotating wheel are set to above fixed frame, the rotating wheel
Central shaft is flexibly connected with fixed frame, and the central shaft of the rotating wheel engages flexible connection, institute with one end of the second driving belt
It states rotating sliding bar one end to connect with rotating wheel front surface edge movable by hinge, the rotating sliding bar other end passes through hinge
Chain is flexibly connected with push-and-pull block, and the connecting rod upper end is with push-and-pull block by being welded vertical connection, the connecting rod upper end and cunning
Part is connected by electric welding, and the saddle is placed on slide bar outer surface and is gap-matched, and the spud pile is set to slide bar both ends,
The slide bar both ends are connect with spud pile by bolt spiral, and the welding block is set to epimere in connecting rod, the telescopic rod one
End is welded by welding block and connecting rod, and the telescopic rod other end passes through glue Adherents junction with elastic piece.
Further, the elastic piece is set to the interlude of laddertron and between Liang Ge one-way flows mechanism, described
When elastic piece is convex, the one-way flow mechanism for being located at beginning is in open state, and the one-way flow mechanism positioned at end is in
When closed state, the elastic piece are recessed, the one-way flow mechanism for being located at beginning is in closed state, and positioned at the list of end
It is in open state to flowing mechanism.
Further, the one-way flow mechanism by hanger bracket, inlay bar, connecting spring, baffle, tie rod, pedestal and form,
The bar of inlaying is described to inlay inside bar upper end insertion hanger bracket and be slidably connected below hanger bracket, the connecting spring
Below hanger bracket, institute's connecting spring upper and lower ends are connected with hanger bracket, baffle by electric welding respectively, and the tie rod is set to
Below baffle and the upper end is connected with baffle, and the tie rod lower end is movably connected with the base.
Further, kinetic energy converting electrical energy mechanism is by third driving belt, belt pulley, the 4th driving belt, driving
Wheel, cutting rack, the poles S magnetic patch, the poles N magnetic patch, rectifier composition, third driving belt one end is engaged with the central shaft of rotating wheel
Flexible connection, the third driving belt other end engage flexible connection with the wheel shaft of belt pulley, and the 4th driving belt is set
Flexible connection is engaged among belt pulley, driving wheel and with wheel shaft, the driving wheel is set to intermediate in front of cutting rack and passes through electricity
Weldering is connected, the cutting rack be set between the poles S magnetic patch and the poles N magnetic patch, the rectifier be set to the poles N magnetic patch left side side and with cut
Frame electrical connection is cut, the rectifier is electrically connected by electric wire with sampling warning light.
Advantageous effect
A kind of sampler of bioreactor of the present invention passes through bioreactor reality under conditions of connecting power supply
It now reacts, after the completion of reaction, bioreactor can send out electric signal to electromagnet, and electromagnet energizing magnetic attracts armature block
Band driven fork upper end is swung to the right, and the lower end of swing rod is then swung to the left and upper rack is driven to be moved to the left, and drive spur gear is in
Rotation counterclockwise, while can move right set on lower rack below and traction swing rod upper end is pushed to swing to the right, swing rod is drawn
One end of traction rope is pulled, and the other end of traction rope is slided and is driven along on upright sliding bar around lifting saddle is pullled after fixed pulley
Dynamic electricity end move up with electrostatic end in contact, connect the power supply of driving motor, driving motor, which is started to work, simultaneously passes through the first driving belt
The first transmission gear is driven to rotate, and the first transmission gear by the gear teeth by driving the rotation of the second transmission gear, the second driving cog
Wheel drives rotating wheel rotation by the second driving belt again, when rotating wheel rotates one end of rotating sliding bar to left side side,
The other end of rotating sliding bar then drives push-and-pull block, connecting rod, saddle to be slided to the left along slide bar, passes through welding block and company at this time
The telescopic rod of extension bar welding pull elastic piece it is convex when, the one-way flow mechanism for being located at beginning is in open state, and is located at
The one-way flow mechanism of end is in closed state, and sample works as rotating wheel because air pressure is inhaled among laddertron from laddertron beginning
When one end of rotating sliding bar is rotated to right side side, when elastic piece is recessed at this time, it is located at the one-way flow mechanism at beginning
In closed state, and positioned at end one-way flow mechanism be in open state, sample because air pressure from trapezoidal pipe end through connecting tube
It is squeezed into sample cell, so cycle completes sampling；While rotating wheel rotates, belt pulley is driven by third driving belt
Rotation, and belt pulley drives driving wheel further through the 4th driving belt, is quickly rotated therewith with the cutting rack of driving wheel welding, it is right
Existing magnetic field line is cut and is produced electricl energy between the poles S magnetic patch, the poles N magnetic patch, passes through electric wire after the rectified device processing of electric energy
It is conveyed to sampling warning light, it is sampling state that sampling warning light, which lights prompt at this time,.
A kind of sampler of bioreactor of the present invention can be in bioreactor by being equipped with Autosampler
It automatically begins to sample after completing reaction, while kinetic energy when sampling is subjected to recycling and is converted into electric energy and provides electric energy for warning light,
Effectively enhance the automation performance of the sampler of bioreactor, more hommization.
Description of the drawings
Upon reading the detailed description of non-limiting embodiments with reference to the following drawings, other feature of the invention,
Objects and advantages will become more apparent upon：
Fig. 1 is a kind of structural schematic diagram of the sampler of bioreactor of the present invention.
Fig. 2 is a kind of structural plan figure of Autosampler of the present invention.
Fig. 3 is a kind of detailed construction schematic diagram of Autosampler of the present invention.
Fig. 4 is a kind of working state figure of Autosampler of the present invention.
In figure：Bioreactor -1, digital display screen -2, pressure gauge -3, control panel -4, bottom block -5, automatic sampling
Device -6, supporting rack -7, delay cylinder -8, connecting tube -9, sample cell -10, electromagnetic drive mechanism -60, traction connect motor structure -61, electricity
Machine driving mechanism -62, push-and-pull sampling mechanism -63, laddertron -64, one-way flow mechanism -65, kinetic energy converting electrical energy mechanism -66,
Sample warning light -67, closure -68, electromagnet -600, swing rod -601, fixed plate -602, armature block -603, upper rack -
604, the first spring -605, spur gear -606, lower rack -607, second spring -608, wheel carrier -610, traction swing rod -611, hinge
Chain fulcrum -612, lantern ring -613, camber line bar -614, third spring -615, traction rope -616, fixed pulley -617, upright sliding bar -
618, saddle -619, the 4th spring -6110, limited block -6111, dynamic electric end -6112, driving motor -620, motor cabinet-are lifted
621, electrostatic end -622, the first driving belt -623, the first transmission gear -624, the second transmission gear -625, the second transmission skin
Band -626, fixed frame -631, rotating sliding bar -632, push-and-pull block -633, connecting rod -634, saddle -635, is slided rotating wheel -630
Bar -636, welding block -638, telescopic rod -639, elastic piece -6310, hanger bracket -650, inlays bar -651, connects spud pile -637
Connect spring -652, baffle -653, tie rod -654, pedestal -655, third driving belt -660, belt pulley -661, the 4th transmission skin
Band -662, driving wheel -663, cutting rack -664, the poles S magnetic patch -665, the poles N magnetic patch -666, rectifier -667.
Specific implementation mode
To make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, with reference to
Specific implementation mode, the present invention is further explained.
- Fig. 4 is please referred to Fig.1, the present invention provides a kind of technical solution of the sampler of bioreactor：Its structure includes
It includes bioreactor 1, digital display screen 2, pressure gauge 3, control panel 4, bottom block 5, Autosampler 6, supporting rack 7, be detained
Cylinder 8, connecting tube 9, sample cell 10, the bioreactor 1 are set to 5 upper right of bottom block, and the digital display screen 2 is embedded in
1 front surface top of bioreactor, the pressure gauge 3 are set to below 1 front surface of bioreactor, and the control panel 4 is inlayed
Below 1 front surface of bioreactor and it is located at 3 left side side of pressure gauge, the Autosampler 6 is set to 5 upper left of bottom block
And connected by connection flexible pipe and the perforation of bioreactor 1, support frame as described above 7 be uniformly equidistantly set to the top of Autosampler 6 and
Vertical connection is engaged in its lower end and 6 upper surface of Autosampler by screw thread, the delay cylinder 8 be set to 7 inside of supporting rack and with
Vertical connection is engaged in 7 upper end of supporting rack by screw thread, and 9 lower end of the connecting tube is connected with the perforation of 8 perpendicular shape of cylinder is detained, described
The perforation of 9 upper end of connecting tube and sample cell 10 connects, the Autosampler 6 by electromagnetic drive mechanism 60, traction connect motor structure 61,
Motor-driven mechanism 62, push-and-pull sampling mechanism 63, laddertron 64, one-way flow mechanism 65, kinetic energy converting electrical energy mechanism 66, sampling
Warning light 67, closure 68 form, the electromagnetic drive mechanism 60 be set to 68 upper right corner of closure and with bioreactor 1
Electrical connection, the traction connect motor structure 61 set on 60 lower section of electromagnetic drive mechanism, and the traction connects motor structure 61 and driven with motor
Mechanism 62 is electrically connected, and the push-and-pull sampling mechanism 63 is set to 62 left side side of motor-driven mechanism and passes through driving belt engagement activity
Connection, the laddertron 64 are obliquely set to 68 inside of closure and with closure 68 by being welded perforation connection, institute
One-way flow mechanism 65 is stated to set there are two and be respectively arranged on inside the corner of laddertron 64, kinetic energy converting electrical energy mechanism 66
It is engaged above push-and-pull sampling mechanism 63 and by driving belt and is flexibly connected, it is outer that the sampling warning light 67 is embedded in closing
68 surface of shell and be electrically connected with kinetic energy converting electrical energy mechanism 66,68 cylinder structure of the closure and on bottom block 5
Surface by electric welding be connected, the electromagnetic drive mechanism 60 by electromagnet 600, swing rod 601, fixed plate 602, armature block 603,
Upper rack 604, the first spring 605, spur gear 606, lower rack 607, second spring 608 form, and the electromagnet 600 is embedded in
68 upper right corner inner wall of closure, the swing rod 601 are set to 600 lower left of electromagnet and pass through articulate with fixed plate 602
Connection, the armature block 603 are set to 601 upper end of swing rod and pass through glue Adherents junction, the lower end of the swing rod 601 and upper rack
604 are connected by articulate, and the upper rack 604 is set to 606 top of spur gear and is flexibly connected by gear teeth meshing, described
First spring 605 is set to 604 right side side of upper rack and is connected by electric welding, and the lower rack 607 is set to 606 lower section of spur gear
And be flexibly connected by gear teeth meshing, the second spring 608 is set to 607 left side side of rack and is connected by electric welding, described
Traction connects motor structure 61 by wheel carrier 610, traction swing rod 611, hinging fulcrum 612, lantern ring 613, camber line bar 614, third spring
615, traction rope 616, fixed pulley 617, upright sliding bar 618, lifting saddle 619, the 4th spring 6110, limited block 6111, dynamic electricity
6112 composition of end, the traction swing rod 611 is in a vertical shape to be set among wheel carrier 610 and is flexibly connected by hinging fulcrum 612, institute
It states lantern ring 613 to be set to traction 611 lower end of swing rod and be in integrated molding structure, the lantern ring 613 is embedded in 614 outer surface of camber line bar
And be gap-matched, the third spring 615 is set to 613 right side side of lantern ring and is connected by electric welding, the traction rope 616
One end is intertwined and connected with 611 upper end of traction swing rod, and 616 other end of the traction rope twines around fixed pulley 617 and lifting saddle 619
Around connection, the lifting saddle 619 is placed on 618 outer surface of upright sliding bar and is gap-matched, and the 4th spring 6110 is set
Be connected in lifting saddle 619 lower section and by electric welding, the limited block 6111 be set in 618 middle and lower sections of upright sliding bar and in
Upright sliding bar 618 is in integrated molding structure, the dynamic electric end 6112 be set to lifting 619 left side side of saddle and with motor driving machine
Structure 62 is electrically connected, and the motor-driven mechanism 62 is by driving motor 620, motor cabinet 621, electrostatic end 622, the first driving belt
623, the first transmission gear 624, the second transmission gear 625, the second driving belt 626 composition, the driving motor 620 are set to electricity
It is connected above engine base 621 and by electric welding, the driving motor 620 passes through motor cabinet 621 and 68 spiral inner wall of closure
Connection, the electrostatic end 622 are set to 620 right side side of driving motor and right over dynamic electric ends 6112, the first transmission skin
It is set between driving motor 620, the first transmission gear 624 with 623 and is driven with the power output shaft of driving motor 620, first
The wheel shaft engagement flexible connection of gear 624, second transmission gear 625 are set to 624 left side side of the first transmission gear and pass through
Gear teeth meshing be flexibly connected, second driving belt 626 be set to the second transmission gear 625, push-and-pull sampling mechanism 63 between and
Flexible connection, the push-and-pull sampling mechanism 63 are engaged with the central shaft of the wheel shaft of the second driving belt 626, push-and-pull sampling mechanism 63
By rotating wheel 630, fixed frame 631, rotating sliding bar 632, push-and-pull block 633, connecting rod 634, saddle 635, slide bar 636, fix
Stake 637, welding block 638, telescopic rod 639, elastic piece 6310 form, and the rotating wheel 630 is set to 631 top of fixed frame, described
The central shaft of rotating wheel 630 is flexibly connected with fixed frame 631, the central shaft of the rotating wheel 630 and the second driving belt 626
One end engagement flexible connection, described 632 one end of rotating sliding bar are connect by hinge with 630 front surface edge movable of rotating wheel,
632 other end of rotating sliding bar is flexibly connected by hinge with push-and-pull block 633,634 upper end of the connecting rod and push-and-pull block
633 by being welded vertical connection, and 634 upper end of the connecting rod is connected with saddle 635 by electric welding, and the saddle 635 is placed on
636 outer surface of slide bar and be gap-matched, the spud pile 637 is set to 636 both ends of slide bar, 636 both ends of the slide bar with it is solid
Determine stake 637 to connect by bolt spiral, the welding block 638 is set to epimere in connecting rod 634, and 639 one end of the telescopic rod is logical
It crosses welding block 638 to weld with connecting rod 634,639 other end of the telescopic rod passes through glue Adherents junction, institute with elastic piece 6310
Elastic piece 6310 is stated set on the interlude of laddertron 64 and between Liang Ge one-way flows mechanism 65, the elastic piece 6310 is in
When convex, the one-way flow mechanism 65 for being located at beginning is in open state, and positioned at the one-way flow mechanism 65 of end in closing
State, when the elastic piece 6310 is recessed, the one-way flow mechanism 65 for being located at beginning is in closed state, and positioned at end
One-way flow mechanism 65 be in open state, the one-way flow mechanism 65 by hanger bracket 650, inlay bar 651, connecting spring 652,
Baffle 653, tie rod 654, pedestal 655 form, and the bar 651 of inlaying is described to inlay 651 upper end of bar set on 650 lower section of hanger bracket
It inside embedded hanger bracket 650 and is slidably connected, the connecting spring 652 is set to below hanger bracket 650, on institute's connecting spring 652
Lower both ends are connected with hanger bracket 650, baffle 653 by electric welding respectively, and the tie rod 654 is set to the lower section of baffle 653 and thereon
End is connected with baffle 653, and 654 lower end of the tie rod is flexibly connected with pedestal 655, and kinetic energy converting electrical energy mechanism 66 is by the
Three driving belts 660, belt pulley 661, the 4th driving belt 662, driving wheel 663, cutting rack 664, the poles S magnetic patch 665, the poles N magnetic
Block 666, rectifier 667 form, and described 660 one end of third driving belt engages flexible connection, institute with the central shaft of rotating wheel 630
It states 660 other end of third driving belt and engages flexible connection with the wheel shaft of belt pulley 661, the 4th driving belt 662 is set to
Flexible connection is engaged among belt pulley 661, driving wheel 663 and with wheel shaft, the driving wheel 663 is set in 664 front of cutting rack
Between and by electric welding be connected, the cutting rack 664 be set between the poles S magnetic patch 665 and the poles N magnetic patch 666, the rectifier 667
It is electrically connected set on 666 left side side of the poles N magnetic patch and with cutting rack 664, the rectifier 667 passes through electric wire and 67 electricity of sampling warning light
Connection.
A kind of sampler of bioreactor of the present invention, its working principle is that：Under conditions of connecting power supply, pass through
Bioreactor 1 realizes reaction, and after the completion of reaction, bioreactor 1 can send out electric signal to electromagnet 600, and electromagnet 600 is logical
Electricity generates magnetic attraction armature block 603 and is swung to the right with 601 upper end of driven fork, and the lower end of swing rod 601 is then swung to the left and band
Dynamic upper rack 604 is moved to the left, and drives spur gear 606 in rotation counterclockwise, while can to the right set on lower rack 607 below
It moves and 611 upper end of traction swing rod is pushed to swing to the right, swing rod 611 pulls one end of traction rope 616, and traction rope 616 is another
One end bypass pull after fixed pulley 617 lifting saddle 619 slided on upright sliding bar 618 and drive dynamic electric end 6112 move up with it is quiet
Electric end 622 contacts, and connects the power supply of driving motor 620, and driving motor 620 starts to work and passes through 623 band of the first driving belt
Dynamic first transmission gear 624 rotation, and the first transmission gear 624 is by the gear teeth by driving the second transmission gear 625 to rotate, second
Transmission gear 625 drives rotating wheel 630 to rotate by the second driving belt 626 again, when rotating wheel 630 is by rotating sliding bar 632
One end when rotating to left side side, the other end of rotating sliding bar 632 then drives push-and-pull block 633, connecting rod 634,635 edge of saddle
It slide bar 636 to slide to the left, the telescopic rod 639 welded with connecting rod 634 by welding block 638 at this time pulls elastic piece 6310 and is in
When convex, the one-way flow mechanism 65 for being located at beginning is in open state, and positioned at the one-way flow mechanism 65 of end in closing
State, sample is because air pressure is inhaled among laddertron 64 from 64 beginning of laddertron, when rotating wheel 630 is by rotating sliding bar 632
When one end is rotated to right side side, when elastic piece 6310 is recessed at this time, it is located at the one-way flow mechanism 65 at beginning in closing shape
State, and be in open state positioned at the one-way flow mechanism 65 of end, sample is squeezed through connecting tube 9 because of air pressure from 64 end of laddertron
Enter sample cell 10, so cycle completes sampling；While rotating wheel 630 rotates, skin is driven by third driving belt 660
Belt wheel 661 rotates, and belt pulley 661 drives driving wheel 663 further through the 4th driving belt 662, is cut with what driving wheel 663 welded
The quickly rotation therewith of frame 664 is cut, existing magnetic field line is cut and generates electricity between the poles S magnetic patch 665, the poles N magnetic patch 666
Can, the rectified device 667 of electric energy is conveyed to by electric wire after handling and samples warning light 67, and sampling warning light 67 lights prompt and is at this time
Sampling state.
Problems solved by the invention is that sampler the degree of automation of the bioreactor of the prior art is relatively low, increases work
Make the workload of personnel, the present invention is combined with each other by above-mentioned component, can be in biological respinse by being equipped with Autosampler
Device automatically begins to sample after completing reaction, while kinetic energy when sampling is carried out recycling and is converted into electric energy and provides electricity for warning light
Can, effectively enhance the automation performance of the sampler of bioreactor, more hommization.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill
For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from the present invention spirit or
In the case of essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action
Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state
Bright restriction, it is intended that including all changes that come within the meaning and range of equivalency of the claims in the present invention
It is interior.Any reference signs in the claims should not be construed as limiting the involved claims.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiment being appreciated that.
Claims (8)
1. a kind of sampler of bioreactor, structure includes bioreactor (1), digital display screen (2), pressure gauge
(3), control panel (4), bottom block (5), Autosampler (6), supporting rack (7), delay cylinder (8), connecting tube (9), sample cell
(10), it is characterised in that：
The bioreactor (1) is set to bottom block (5) upper right, and the digital display screen (2) is embedded in bioreactor
(1) front surface top, the pressure gauge (3) are set to below bioreactor (1) front surface, and the control panel (4) is embedded in
Below bioreactor (1) front surface and it is located at pressure gauge (3) left side side, the Autosampler (6) is set on bottom block (5)
It is connected on the left of side and by connection flexible pipe and bioreactor (1) perforation, support frame as described above (7) is uniformly equidistant to be set to automatic sampling
Above device (6) and vertical connection is engaged in its lower end with Autosampler (6) upper surface by screw thread, and the delay cylinder (8) is set to
Supporting rack (7) is internal and engages vertical connection, connecting tube (9) lower end and delay cylinder by screw thread with supporting rack (7) upper end
(8) perpendicular shape perforation connection, connecting tube (9) upper end are connected with sample cell (10) perforation；
The Autosampler (6) connects motor structure (61) by electromagnetic drive mechanism (60), traction, motor-driven mechanism (62), pushes away
Draw sampling mechanism (63), laddertron (64), one-way flow mechanism (65), kinetic energy converting electrical energy mechanism (66), sampling warning light
(67), closure (68) forms, and the electromagnetic drive mechanism (60) is set to closure (68) upper right corner and and biological respinse
Device (1) is electrically connected, and the traction connects motor structure (61) below electromagnetic drive mechanism (60), and the traction connects motor structure (61)
It is electrically connected with motor-driven mechanism (62), the push-and-pull sampling mechanism (63) is set to motor-driven mechanism (62) left side side and passes through
Driving belt engagement flexible connection, the laddertron (64) are obliquely set to closure (68) inside and and closure
(68) by being welded perforation connection, the one-way flow mechanism (65) sets there are two and is respectively arranged on the corner of laddertron (64)
Inside, kinetic energy converting electrical energy mechanism (66) are set to above push-and-pull sampling mechanism (63) and are connected by driving belt engagement activity
It connects, the sampling warning light (67) is embedded in closure (68) surface and is electrically connected with kinetic energy converting electrical energy mechanism (66), institute
It states the cylinder structure of closure (68) and is connected by electric welding with bottom block (5) upper surface.
2. a kind of sampler of bioreactor according to claim 1, it is characterised in that：The electromagnetic drive mechanism
(60) by electromagnet (600), swing rod (601), fixed plate (602), armature block (603), upper rack (604), the first spring
(605), spur gear (606), lower rack (607), second spring (608) composition, the electromagnet (600) are embedded in closure
(68) upper right corner inner wall, the swing rod (601) are set to electromagnet (600) lower left and pass through articulate with fixed plate (602)
Connection, the armature block (603) are set to swing rod (601) upper end and by glue Adherents junctions, the lower end of the swing rod (601) with
Upper rack (604) is connected by articulate, and the upper rack (604) is set to above spur gear (606) and passes through gear teeth meshing
Flexible connection, first spring (605) are set to upper rack (604) right side side and are connected by electric welding, the lower rack
(607) it is set to below spur gear (606) and is flexibly connected by gear teeth meshing, the second spring (608) is set to rack (607)
Left side side and by electric welding be connected.
3. a kind of sampler of bioreactor according to claim 1, it is characterised in that：The traction connects motor structure
(61) by wheel carrier (610), traction swing rod (611), hinging fulcrum (612), lantern ring (613), camber line bar (614), third spring
(615), traction rope (616), fixed pulley (617), upright sliding bar (618), lifting saddle (619), the 4th spring (6110), limit
Block (6111), dynamic electric end (6112) form, and the traction swing rod (611) is in a vertical shape to be set among wheel carrier (610) and pass through hinge
Chain fulcrum (612) is flexibly connected, and the lantern ring (613) is set to traction swing rod (611) lower end and is in integrated molding structure, described
Lantern ring (613) is embedded in camber line bar (614) outer surface and is gap-matched, and it is right that the third spring (615) is set to lantern ring (613)
Side and by electric welding be connected, described traction rope (616) one end with draw swing rod (611) upper end be intertwined and connected, the traction
Rope (616) other end is intertwined and connected around fixed pulley (617) and lifting saddle (619), and the lifting saddle (619) is placed on vertically
It slide bar (618) outer surface and is gap-matched, the 4th spring (6110) is set to below lifting saddle (619) and passes through electricity
Weldering is connected, the limited block (6111) be set in upright sliding bar (618) middle and lower sections and in upright sliding bar (618) in integrated
Molding structure, the dynamic electric end (6112) are set to lifting saddle (619) left side side and are electrically connected with motor-driven mechanism (62).
4. a kind of sampler of bioreactor according to claim 1 or 3, it is characterised in that：The motor driving
Mechanism (62) is by driving motor (620), motor cabinet (621), electrostatic end (622), the first driving belt (623), the first driving cog
(624), the second transmission gear (625), the second driving belt (626) composition are taken turns, the driving motor (620) is set to motor cabinet
(621) it is connected above and by electric welding, the driving motor (620) passes through motor cabinet (621) and closure (68) inner wall
Spiral connects, and the electrostatic end (622) is set to driving motor (620) right side side and right over dynamic electric end (6112), described
First driving belt (623) is set to dynamic between driving motor (620), the first transmission gear (624) and with driving motor (620)
The wheel shaft engagement flexible connection of power output shaft, the first transmission gear (624), second transmission gear (625) are set to first and pass
It moving gear (624) left side side and is flexibly connected by gear teeth meshing, second driving belt (626) is set to the second transmission gear
(625), between push-and-pull sampling mechanism (63) and with the center of the wheel shaft of the second driving belt (626), push-and-pull sampling mechanism (63)
Axis engagement flexible connection.
5. a kind of sampler of bioreactor according to claim 1, it is characterised in that：The push-and-pull sampling mechanism
(63) by rotating wheel (630), fixed frame (631), rotating sliding bar (632), push-and-pull block (633), connecting rod (634), saddle
(635), slide bar (636), spud pile (637), welding block (638), telescopic rod (639), elastic piece (6310) composition, the rotation
It takes turns (630) to be set to above fixed frame (631), the central shaft of the rotating wheel (630) is flexibly connected with fixed frame (631), described
The central shaft of rotating wheel (630) engages flexible connection, the rotating sliding bar (632) with one end of the second driving belt (626)
One end is connect by hinge with rotating wheel (630) front surface edge movable, and rotating sliding bar (632) other end passes through hinge
It is flexibly connected with push-and-pull block (633), connecting rod (634) upper end is with push-and-pull block (633) by being welded vertical connection, the company
Extension bar (634) upper end is connected with saddle (635) by electric welding, and the saddle (635) is placed on slide bar (636) outer surface and use
Clearance fit, the spud pile (637) are set to slide bar (636) both ends, and slide bar (636) both ends pass through with spud pile (637)
Bolt spiral connects, and the welding block (638) is set to epimere in connecting rod (634), and described telescopic rod (639) one end passes through welding
Block (638) is welded with connecting rod (634), and telescopic rod (639) other end passes through glue Adherents junction with elastic piece (6310).
6. a kind of sampler of bioreactor according to claim 5, it is characterised in that：The elastic piece (6310)
Set on laddertron (64) interlude and between Liang Ge one-way flows mechanism (65), the elastic piece (6310) is convex
When, the one-way flow mechanism (65) for being located at beginning is in open state, and positioned at the one-way flow mechanism (65) of end in closing shape
When state, the elastic piece (6310) are recessed, the one-way flow mechanism (65) for being located at beginning is in closed state, and is located at end
One-way flow mechanism (65) be in open state.
7. a kind of sampler of bioreactor according to claim 1 or 6, it is characterised in that：The one-way flow
Mechanism (65) by hanger bracket (650), inlay bar (651), connecting spring (652), baffle (653), tie rod (654), pedestal (655)
Composition, the bar (651) of inlaying are described to inlay in bar (651) upper end insertion hanger bracket (650) below hanger bracket (650)
It portion and is slidably connected, the connecting spring (652) is set to below hanger bracket (650), institute connecting spring (652) upper and lower ends difference
It is connected by electric welding with hanger bracket (650), baffle (653), the tie rod (654) is set to below baffle (653) and the upper end
It is connected with baffle (653), tie rod (654) lower end is flexibly connected with pedestal (655).
8. a kind of sampler of bioreactor according to claim 1, it is characterised in that：The kinetic energy converting electrical energy
Mechanism (66) is by third driving belt (660), belt pulley (661), the 4th driving belt (662), driving wheel (663), cutting rack
(664), the poles S magnetic patch (665), the poles N magnetic patch (666), rectifier (667) composition, described third driving belt (660) one end and rotation
The central shaft engagement flexible connection of runner (630), the wheel shaft of third driving belt (660) other end and belt pulley (661)
Engagement flexible connection, the 4th driving belt (662) are engaged among belt pulley (661), driving wheel (663) and with wheel shaft
Flexible connection, the driving wheel (663) are set to intermediate in front of cutting rack (664) and are connected by electric welding, the cutting rack
(664) it is set between the poles S magnetic patch (665) and the poles N magnetic patch (666), the rectifier (667) is set to the poles N magnetic patch (666) left side side
And be electrically connected with cutting rack (664), the rectifier (667) is electrically connected by electric wire with sampling warning light (67).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810228079.1A CN108562459B (en) | 2018-03-20 | 2018-03-20 | Sampling device of bioreactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810228079.1A CN108562459B (en) | 2018-03-20 | 2018-03-20 | Sampling device of bioreactor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108562459A true CN108562459A (en) | 2018-09-21 |
| CN108562459B CN108562459B (en) | 2020-12-04 |
Family
ID=63531874
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810228079.1A Active CN108562459B (en) | 2018-03-20 | 2018-03-20 | Sampling device of bioreactor |
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| Country | Link |
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| CN (1) | CN108562459B (en) |
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| US5506791A (en) * | 1989-12-22 | 1996-04-09 | American Sigma, Inc. | Multi-function flow monitoring apparatus with multiple flow sensor capability |
| CA2073512A1 (en) * | 1990-11-13 | 1992-05-14 | William G. Hungerford | Automatic fluid sampling and monitoring apparatus and method |
| CN201695039U (en) * | 2010-06-06 | 2011-01-05 | 青岛众瑞智能仪器有限公司 | System for monitoring pathogenic microorganism aerosol pollution groups |
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| Publication number | Publication date |
|---|---|
| CN108562459B (en) | 2020-12-04 |
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