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CN108553543A - A kind of zicao soft plaster and preparation method thereof - Google Patents

A kind of zicao soft plaster and preparation method thereof Download PDF

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CN108553543A
CN108553543A CN201810652389.6A CN201810652389A CN108553543A CN 108553543 A CN108553543 A CN 108553543A CN 201810652389 A CN201810652389 A CN 201810652389A CN 108553543 A CN108553543 A CN 108553543A
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parts
oil
preparation
soft plaster
zicao soft
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马倩
张成虎
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Nanjing University of Information Science and Technology
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Nanjing University of Information Science and Technology
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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Abstract

A kind of zicao soft plaster and preparation method thereof includes following component with mass fraction calculating:10 15 parts of Asian puccoon, 69 parts of pine needle, 69 parts of oenothera biennis, 69 parts of honeysuckle, 69 parts of folium artemisiae argyi, 69 parts of Radix Angelicae Sinensis, 69 parts windproof, 69 parts of glutinous rehmannia, 69 parts of the root of Dahurain angelica, 69 parts of frankincense, 69 parts of myrrh, 69 parts of Radix Glycyrrhizae, 69 parts of dried peppermint leaf, 60 65 parts of beeswax, 0.5 1 parts of tea tree ethereal oil, 280 350 parts of vegetable oil.Zicao soft plaster of the present invention is formed using a variety of prepared from traditional Chinese medicines, can effectively prevent bite by mosquitos, antipruritic, anti-inflammatory, antiallergy etc..Ingredient is nontoxic degradable, does not cause damages to ambient enviroment.The method of the present invention preparation process is simple, easy to implement, and production efficiency is high.

Description

一种紫草膏及其制备方法A kind of comfrey paste and preparation method thereof

技术领域technical field

本发明属于膏状药物制备技术领域,具体涉及一种紫草膏及其制备方法。The invention belongs to the technical field of paste medicine preparation, and in particular relates to a comfrey paste and a preparation method thereof.

背景技术Background technique

近年来由于大气环境日益恶化,由此导致的皮肤问题更是错综复杂。传统的风油精、花露水、清凉油等日用单品功效单一,而且大多都添加有化学防腐成分和色素香精,不仅不能解决上述复杂的皮肤问题,还会对人的皮肤造成危害,安全得不到保障。In recent years, due to the deteriorating atmospheric environment, the resulting skin problems are even more complicated. Traditional essential oils, toilet water, cooling oils and other daily-use items have single effects, and most of them are added with chemical antiseptic ingredients and pigments and essences. Not only can they not solve the above-mentioned complex skin problems, but they will also cause harm to human skin, which is unsafe. to guarantee.

紫草膏的主要成分是紫草,性味甘咸、寒,能凉血活血、清热解毒、透疹。《本草纲目》里这样描述紫草膏:“治斑疹、痘素,活血凉血,利大肠”。据药理研究,紫草的主要化学成分为多种蒽醌类化合物,具有解热、消炎、抗过敏、抗病毒、抗真菌、抗癌和免疫调节作用等作用。松针提取物可用于扩张动脉血管,增加红血球携氧能力,促进血液循环,改善毛细血管的机能,提高免疫力,增加荷尔蒙的分泌,强精,使身体的组织年轻化。在这之前,少有文献提及将松针引入紫草膏。The main component of Zicao paste is comfrey, which is sweet, salty and cold in nature, can cool blood and activate blood, clear heat and detoxify, and relieve rash. "Compendium of Materia Medica" describes Zicao ointment in this way: "cures macule and pox, activates blood and cools blood, and benefits the large intestine." According to pharmacological research, the main chemical components of comfrey are various anthraquinone compounds, which have antipyretic, anti-inflammatory, anti-allergic, anti-viral, anti-fungal, anti-cancer and immunoregulatory effects. Pine needle extract can be used to expand arteries, increase the oxygen-carrying capacity of red blood cells, promote blood circulation, improve the function of capillaries, improve immunity, increase hormone secretion, strengthen essence, and rejuvenate body tissues. Prior to this, there were few literatures mentioning the introduction of pine needles into comfrey paste.

一般的,我们引入了紫草膏常用的中草药成分,如:当归、防风、地黄、白芷、乳香、没药、甘草等,能够有效地防治蚊虫叮咬、止痒、消炎、抗过敏等,所含成分无毒无害可降解,不对周围环境造成危害。除此之外,本发明的紫草膏还引进月见草、薄荷叶和金银花三种具有清热、解毒、消炎、抗菌等作用的草本植物。Generally, we have introduced Chinese herbal ingredients commonly used in comfrey ointment, such as: angelica, windproof, rehmannia glutinosa, angelica, frankincense, myrrh, licorice, etc., which can effectively prevent and control mosquito bites, relieve itching, anti-inflammatory, anti-allergic, etc. The ingredients are non-toxic, harmless and biodegradable, and do not cause harm to the surrounding environment. In addition, the comfrey paste of the present invention also introduces three kinds of herbal plants, including evening primrose, mint leaves and honeysuckle, which have the functions of clearing away heat, detoxification, anti-inflammatory and antibacterial.

夏天天气炎热,蚊虫叮咬、发炎、湿疹、干燥等问题为常见之事,严重的时候甚至会产生过敏反应。痛痒之时,若是我们护理不好的话,极易感染和传播疾病,影响我们的学习、工作和生活。因此,开发一款天然、环保、安全、有效的蚊虫叮咬防治、湿疹、发炎、干燥等问题的产品,符合市场需求,具有广阔的应用前景和良好的发展潜力。The weather is hot in summer, and mosquito bites, inflammation, eczema, dryness and other problems are common. In severe cases, allergic reactions may even occur. When we are in pain, if we do not take good care of it, we will be very easy to infect and spread diseases, which will affect our study, work and life. Therefore, the development of a natural, environmentally friendly, safe and effective product for the prevention and treatment of mosquito bites, eczema, inflammation, dryness and other problems meets market demand and has broad application prospects and good development potential.

发明内容Contents of the invention

本发明的目的是提供一种消炎抗菌手工皂及其制备方法,可以有效解决现有生产的香皂长期使用对皮肤造成伤害,产生过敏等问题,以及利用天然物质萃取提炼使手工皂具备消炎抗菌的作用。The purpose of the present invention is to provide an anti-inflammatory and antibacterial handmade soap and its preparation method, which can effectively solve the problems of skin damage and allergies caused by the long-term use of existing soaps, and use natural substance extraction to make handmade soap have anti-inflammatory and antibacterial properties effect.

本发明是通过以下技术方案实现的:The present invention is achieved through the following technical solutions:

一种紫草膏,以质量份数计算包括如下组份:A kind of comfrey paste comprises the following components in parts by mass:

紫草10-15份、松针6-9份、月见草6-9份、金银花6-9份、艾叶6-9份、当归6-9份、防风6-9份、地黄6-9份、白芷6-9份、乳香6-9份、没药6-9份、甘草6-9份、薄荷叶6-9份、蜂蜡60-65份、茶树精油0.5-1份、植物油280-350份。10-15 parts of comfrey, 6-9 parts of pine needles, 6-9 parts of evening primrose, 6-9 parts of honeysuckle, 6-9 parts of mugwort leaves, 6-9 parts of angelica, 6-9 parts of windproof, 6-9 parts of rehmannia , 6-9 parts of Angelica dahurica, 6-9 parts of frankincense, 6-9 parts of myrrh, 6-9 parts of licorice, 6-9 parts of mint leaves, 60-65 parts of beeswax, 0.5-1 part of tea tree essential oil, 280-350 parts of vegetable oil share.

本发明所述的一种紫草膏,其进一步解决的技术方案是,所述的植物油为芝麻油。A kind of comfrey paste of the present invention, its further solution technical solution is that described vegetable oil is sesame oil.

本发明所述的一种紫草膏,其进一步解决的技术方案是,所述的芝麻油为冷轧芝麻油。A kind of comfrey paste described in the present invention, its technical scheme that further solves is that described sesame oil is cold-rolled sesame oil.

权利要求1所述的紫草膏的制备方法,包括如下步骤:The preparation method of comfrey paste described in claim 1, comprises the steps:

(1) 按权利要求1所述组分配比,称取紫草、松针、月见草、薄荷叶、金银花,粉碎并混合,置于植物油中浸泡,过滤,制取浸油Ⅰ;所述植物油为冷轧芝麻油;(1) According to the composition ratio described in claim 1, take comfrey, pine needles, evening primrose, mint leaves, and honeysuckle, pulverize and mix, place in vegetable oil for soaking, filter, and produce immersion oil I; is cold-rolled sesame oil;

(2) 按权利要求1所述的组分配比,称取当归、防风、地黄、白芷、乳香、没药、甘草,粉碎后置于步骤(1)所得的浸油Ⅰ中浸泡,过滤,制取浸油Ⅱ;(2) according to the composition ratio described in claim 1, take angelica, windproof, rehmannia glutinosa, angelica dahurica, frankincense, myrrh, licorice, place after pulverizing in soaking oil I obtained in step (1), filter, and prepare Take immersion oil II;

(3) 按权利要求1所述的组分配比,将蜂蜡置于步骤(2)制得的浸油Ⅱ中,加热至蜂蜡完全熔化;(3) according to the component distribution ratio described in claim 1, beeswax is placed in the immersion oil II that step (2) makes, is heated to beeswax and melts completely;

(4) 按权利要求1所述的组分配比,将茶树精油加入步骤(3)所得产物,搅拌均匀,冷却后得成品。(4) According to the component distribution ratio described in claim 1, the tea tree essential oil is added to the product obtained in step (3), stirred evenly, and obtained finished product after cooling.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(1)中,紫草、松针、月见草、薄荷叶、金银花的粉碎粒径为50-100目。The preparation method of a kind of comfrey paste of the present invention, its technical scheme that further solves is, in described step (1), the comminuted particle size of comfrey, pine needle, evening primrose, peppermint leaf, honeysuckle is 50- 100 mesh.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(1)中,浸泡条件为60-80℃下浸泡3-5天;过滤使用的筛网为100-200目。The preparation method of a kind of comfrey paste described in the present invention, its technical scheme that further solves is, in described step (1), soaking condition is soaking 3-5 days under 60-80 ℃; The screen cloth used for filtering is 100-200 mesh.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(2)中,当归、防风、地黄、白芷、乳香、没药、甘草的粉碎粒径为50-70目。The preparation method of a kind of comfrey paste described in the present invention, its further solution technical scheme is, in described step (2), the pulverized particle size of angelica, windproof, rehmannia glutinosa, angelica dahurica, frankincense, myrrh, licorice is 50 -70 mesh.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(2)中,浸泡条件为60-80℃下浸泡3-5天;过滤使用的筛网为100-200目。The preparation method of a kind of comfrey paste described in the present invention, its technical scheme that further solves is, in described step (2), soaking condition is soaking 3-5 days under 60-80 ℃; The screen cloth used for filtering is 100-200 mesh.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(3)中,加热温度为80 -90℃。The preparation method of a kind of comfrey paste described in the present invention, its further technical solution is that in the step (3), the heating temperature is 80-90°C.

本发明所述的一种紫草膏的制备方法,其进一步解决的技术方案是,所述步骤(4)中,冷却温度为25℃。The preparation method of a kind of comfrey paste described in the present invention, its further technical solution is that in the step (4), the cooling temperature is 25°C.

所述的紫草,性味甘咸、寒,能凉血活血、清热解毒、透疹。《本草纲目》里这样描述紫草膏:“治斑疹、痘素,活血凉血,利大肠”。据药理研究,紫草的主要化学成分为多种蒽醌类化合物,具有解热、消炎、抗过敏、抗病毒、抗真菌、抗癌和免疫调节作用等作用。Described comfrey, nature and flavor are sweet and salty, cold, can cool blood and activate blood, heat-clearing and toxic substances removing, clear rash. "Compendium of Materia Medica" describes Zicao ointment in this way: "cures macule and pox, activates blood and cools blood, and benefits the large intestine." According to pharmacological research, the main chemical components of comfrey are various anthraquinone compounds, which have antipyretic, anti-inflammatory, anti-allergic, anti-viral, anti-fungal, anti-cancer and immunoregulatory effects.

所述的松针不仅能够扩张动脉血管,增加红血球携氧能力,促进血液循环,改善毛细血管的机能,还能提高免疫力,增加荷尔蒙额分泌,强精,使身体的组织年轻化。The pine needles can not only expand the arteries, increase the oxygen-carrying capacity of red blood cells, promote blood circulation, improve the function of capillaries, but also improve immunity, increase hormone secretion, strengthen sperm, and make the tissues of the body rejuvenated.

所述的月见草,能增进血液循环减少脂肪在血管内壁的滞留,消散硬化斑,有助于治疗湿疹和皮肤炎这类皮肤病。此外,月见草浸泡油能促进脂肪代谢,滋润皮肤,抗炎,抗凝血,降血脂,控制高血压等作用。The evening primrose can improve blood circulation, reduce the retention of fat on the inner wall of blood vessels, dissipate hardened plaques, and help treat skin diseases such as eczema and dermatitis. In addition, evening primrose soaked oil can promote fat metabolism, moisturize the skin, anti-inflammation, anti-coagulation, lower blood fat, and control high blood pressure.

所述的金银花性甘、寒,有清热、解毒、消炎的功效,主要抗菌有效成分为绿原酸、异绿原酸,对革兰氏阳性、阴性菌均有一定的抑制作用,对多种皮肤真菌及呼吸道病毒有抑制作用,既能抑制炎性渗出,又能抑制炎性增生,还有促进白细胞的吞噬作用。金银花对金黄色葡萄球菌、白色葡萄球菌、甲型链球菌和乙型链球菌均有明显的抑菌作用,尤其对金黄色葡萄球菌抑菌效果更明显,同时对链球菌、大肠杆菌和痢疾杆菌等多种致病菌也有抑制作用。金银花中活性成分绿原酸具有一定的抗病毒作用,对呼吸道最常见、最主要的合胞病毒和柯萨奇组型病毒具有明显的抑制作用。The honeysuckle is sweet and cold in nature, has heat-clearing, detoxification, and anti-inflammatory effects, and the main antibacterial active ingredients are chlorogenic acid and isochlorogenic acid, which have a certain inhibitory effect on Gram-positive and negative bacteria. Skin fungus and respiratory virus have inhibitory effect, which can not only inhibit inflammatory exudation, but also inhibit inflammatory hyperplasia, and promote the phagocytosis of white blood cells. Honeysuckle has obvious antibacterial effect on Staphylococcus aureus, Staphylococcus albus, Streptococcus A and Streptococcus B, especially for Staphylococcus aureus. and other pathogenic bacteria also have inhibitory effect. Chlorogenic acid, the active ingredient in honeysuckle, has a certain antiviral effect, and has obvious inhibitory effect on the most common and main syncytial virus and Coxsackie virus in the respiratory tract.

所述的艾叶具有抗菌和抗毒的作用,它不仅能止血、抗凝血和抗过敏,还能增强人体对疾病的免疫力。Said Artemisia argyi has antibacterial and antitoxic effects, it can not only stop bleeding, anticoagulant and antiallergic, but also enhance the immunity of human body to diseases.

所述的当归有行血、补血、止痛、润肤之功效,能扩张皮肤的毛细血管,促进血液循环,抗维生素缺乏。The angelica has the effects of promoting blood circulation, nourishing blood, relieving pain, and moisturizing skin, can expand skin capillaries, promote blood circulation, and resist vitamin deficiency.

所述的防风味辛、甘,性微温,气香升散。具有祛风解表,除湿止痛,疏肝解痉,杀虫止痒的功效,主治风寒湿痹,骨节酸痛,长风下血,破伤中风,麻疹难透,风疹搔痒,创疡初起。Described anti-flavor flavor is pungent, sweet, slightly warm in nature, and gas fragrance ascends and loosens. It has the effects of expelling wind and relieving exterior syndrome, dehumidifying and relieving pain, soothing liver and relieving spasm, killing parasites and relieving itching. It is mainly used to treat wind-cold-dampness arthralgia, joint pain, wind-induced bleeding, tetanus apoplexy, difficult to penetrate measles, rubella and itching, and the onset of wounds and ulcers.

所述的地黄,玄参科地黄属多年生草本植物,用于上风伤阴,发斑发疹,阴虚内热,具有止血、抗真菌、抗炎、抗过敏等功效。The rehmannia root, Scrophulariaceae Rehmannia genus is a perennial herbaceous plant, which is used for wind-injured yin, spots and eruptions, yin deficiency and internal heat, and has hemostatic, anti-fungal, anti-inflammatory, anti-allergic and other effects.

所述的白芷,为伞形科当归属的植物。性味归经:辛,温。归肺、胃经。其主要成分为挥发油和香豆素类成分,其抗炎镇痛的有效部位是脂溶性部位,其中具有活性作用的欧前胡素能产生镇痛和广谱抗菌作用,能抑制大肠杆菌、绿脓杆菌及变形杆菌、奥杜盎氏小芽胞癣菌等致病真菌生长。用于祛风散寒,通窍止痛,消肿排脓,痈疽疮疡、皮肤瘙痒、烧烫伤等。The described Angelica dahurica is a plant belonging to the Umbelliferae family Angelica. Meridian distribution of property and flavor: pungent, warm. Return lung, stomach warp. Its main components are volatile oil and coumarin components, and its anti-inflammatory and analgesic effective parts are fat-soluble parts, among which the active imperatorin can produce analgesic and broad-spectrum antibacterial effects, and can inhibit Escherichia coli, Pseudomonas aeruginosa and Growth of pathogenic fungi such as Proteus and Microsporum audouin. For expelling wind and cold, clearing the orifices and relieving pain, reducing swelling and discharging pus, carbuncle sores, skin itching, burns and scalds.

所述的乳香本名薰陆,别名熏陆香、马尾香、乳头香、塌香、天泽香、摩勒香、多伽罗香等,为橄榄科常绿乔木的凝固树脂。因其滴下成乳头状,故亦称乳头香,为薰香原料。除了能阵痛外,还能促进多核白血球增加,以吞噬死亡的血球及细胞,改善新陈代谢,从而起消炎作用。Described frankincense real name Xunlu, alias Xunluxiang, horsetail incense, nipple incense, tatami, Tianze incense, mole incense, dajialuo incense, etc., is the solidified resin of the evergreen trees of the olive family. Because it drips into nipples, it is also called nipple incense, which is a raw material for incense. In addition to pain relief, it can also promote the increase of multi-nucleated white blood cells to phagocytize dead blood cells and cells, improve metabolism, and thus play an anti-inflammatory effect.

所述的没药,又名末药,其他还有明没药、制没药、炙没药、醋炒没药、生没药、生明没药等别称。为橄榄科植物地丁树或哈地丁树的干燥树脂。主治胸腹瘀痛、痛经、经闭、症瘕、跌打损伤、痈肿疮疡、肠痈、目赤肿痛。没药对治疗伤口、皮肤炎效果很好,对支气管炎,咳嗽,细菌感染及鰴菌感染都有帮助。有活血止痛、消肿生肌等功效。Described myrrh, has another name called the end medicine, and other also have other names such as clear myrrh, system myrrh, roast myrrh, vinegar stir-fry myrrh, raw myrrh, raw myrrh and so on. It is the dry resin of the olive tree or hardidin. Cure mainly chest and abdomen stasis and pain, dysmenorrhea, amenorrhea, lump in the abdomen, bruises, carbuncle sores, intestinal abscess, red eyes and swelling. Myrrh is very effective in treating wounds and dermatitis, and is helpful for bronchitis, cough, bacterial infection and fungal infection. It has the effects of promoting blood circulation, relieving pain, reducing swelling and promoting muscle growth.

所述的甘草,名乌拉尔甘草,是一种补益中草药。药用部位是根及根茎,药材性状根呈圆柱形。功能主治清热解毒,祛痰止咳、脘腹等。具有抗炎、抗病毒,和保肝解毒及增强免疫功能等作用。其所含的甘草酸还具有抗癌防癌、干扰素诱生剂及细胞免疫调节剂等功能。此外,甘草酸具有降血脂与抗动脉粥样硬化作用,阻止动脉粥样硬化的形成。Described licorice, name Ural licorice, is a kind of tonic Chinese herbal medicine. The medicinal parts are roots and rhizomes, and the roots are cylindrical in shape. Function cures mainly heat-clearing and toxic substances removing, eliminating phlegm and relieving cough, gastral cavity etc. It has anti-inflammatory, anti-viral, liver-protecting, detoxifying and immune-enhancing effects. The glycyrrhizic acid contained in it also has functions such as anti-cancer and anti-cancer, interferon-inducing agent and cellular immune regulator. In addition, glycyrrhizic acid has the effect of lowering blood fat and anti-atherosclerosis, preventing the formation of atherosclerosis.

所述的薄荷叶是植物薄荷的叶子,主要含薄荷油、薄荷醇以及薄荷酮、异薄荷酮、迷迭香酸等成份。其性凉味辛,有宣散风热、淸头目、透疹之功,具有兴奋大脑、促进血液循环、发汗,与消炎鎭痛、止痒解毒和疏散风热的作用。薄荷叶可以健胃祛风、祛痰、利胆、抗痉挛,改善感发烧、咽喉、肿痛,并消除头痛、牙痛、恶心感及皮肤瘙痒等症状,还可降低血压、滋补心脏。The mint leaves are the leaves of mint plant, mainly containing mint oil, menthol, menthone, isomenthone, rosmarinic acid and other ingredients. It is cool in nature and pungent in taste, and has the functions of dispersing wind-heat, clearing the head, clearing rash, stimulating the brain, promoting blood circulation, sweating, anti-inflammatory pain, relieving itching and detoxification, and evacuating wind-heat. Mint leaves can invigorate the stomach and expel wind, eliminate phlegm, promote choleresis, anti-spasm, improve fever, throat, swelling and pain, and eliminate symptoms such as headache, toothache, nausea and skin itching, and can also lower blood pressure and nourish the heart.

所述的蜂蜡是工蜂腹部下面四对蜡腺分泌购物质。其主要成分有:酸类、游离脂肪酸、游离脂肪醇和碳水化合物。此外,还有类胡萝卜素、维生素A、芳香物质等。性味归经、甘、微温。功能主治收涩,敛疮,生肌,止痛,调理。外用于溃疡不敛,臁疮糜烂,创伤,烧、烫伤,确有良效,实具调和营卫、益气养血,祛风润燥、和血解毒之效能,无不良反应。Described beeswax is that four pairs of wax glands secrete shopping substances under the abdomen of worker bees. Its main components are: acids, free fatty acids, free fatty alcohols and carbohydrates. In addition, there are carotenoids, vitamin A, aromatic substances and so on. Meridian distribution of property and flavor, sweet, slightly warm. Function cures mainly astringent, suppresses sores, promotes granulation, relieves pain, and regulates. Externally used for ulcers, ecchymosis, wounds, burns, and scalds, it has good effects. It has the effects of harmonizing nutrition and health, nourishing qi and nourishing blood, dispelling wind and moistening dryness, harmonizing blood and detoxification, and has no adverse reactions.

所述的茶树精油具有杀菌消炎、收敛毛孔、治疗伤风感冒、咳嗽、鼻炎、哮喘,改善痛经、月经不调及生殖器感染等功效。适用于油性及粉刺皮肤,治疗化脓伤口及灼伤、晒伤、香港脚及头屑。同时,所述的茶树精油还具有使头脑清醒,恢复活力,帮助免疫系统抵抗传染性的疾病,策动白血球形成防护线,以迎战入侵的生物体,并可缩短催病的时间,能改善伤口感染的化脓现象以及疖,清除水痘和带状疤疹所引起的病发症。The tea tree essential oil has the effects of sterilization and anti-inflammation, astringent pores, treatment of cold, cough, rhinitis, asthma, improvement of dysmenorrhea, irregular menstruation and genital infection. Suitable for oily and acne-prone skin, treating purulent wounds and burns, sunburn, foot and dandruff. At the same time, the tea tree essential oil also clears the mind, restores vitality, helps the immune system resist infectious diseases, instigates white blood cells to form a protective line to fight against invading organisms, shortens the time to induce illness, and can improve wound infection Purulent phenomena and boils, clearing chickenpox and shingles caused by the disease.

所述的植物油为芝麻油,芝麻油中含有大量人体必需的脂肪酸,亚油酸。芝麻有补血明目、祛风润肠、生津通乳、益肝养发、强身体、抗衰老之功效。一般人均可食用,每次2-4克即可。习惯性便秘患者早晚空腹喝一口香油,能润肠通便;也适宜患有血管硬化、高血压、冠心病、高脂血症、糖尿病、大便干燥难解、蛔虫性肠梗阻者等病症者食用;香油还适宜从事繁重体力劳动者以及有抽烟习惯和嗜酒的人食用。还未有文献记载用芝麻作为原料制造紫草膏,所以本发明采用芝麻油作为原料之一。The vegetable oil is sesame oil, which contains a large amount of essential fatty acids, linoleic acid. Sesame has the effects of nourishing blood and improving eyesight, dispelling wind and moistening intestines, promoting body fluid and clearing milk, nourishing liver and hair, strengthening the body, and anti-aging. Most people can eat it, 2-4 grams each time. Patients with habitual constipation drink a sip of sesame oil on an empty stomach in the morning and evening, which can moisten the intestines and laxative; it is also suitable for those suffering from arteriosclerosis, hypertension, coronary heart disease, hyperlipidemia, diabetes, dry and intractable stool, roundworm intestinal obstruction and other diseases. Sesame oil is also suitable for people who are engaged in heavy physical labor and people who have smoking habits and alcoholism. Also there is no literature record to use sesame as raw material to make comfrey paste, so the present invention adopts sesame oil as one of raw material.

本发明的有益效果为:The beneficial effects of the present invention are:

1.本发明所述的紫草膏采用多种中草药配制而成,能够有效地防治蚊虫叮咬、止痒、消炎、抗过敏等。所含成分无毒无害可降解,不对周围环境造成危害。本发明方法制备工艺简单、容易实现,生产效率高。1. The comfrey paste of the present invention is prepared from various Chinese herbal medicines, which can effectively prevent mosquito bites, relieve itching, reduce inflammation, and resist allergies. The ingredients contained are non-toxic, harmless and degradable, and do not cause harm to the surrounding environment. The preparation process of the method of the invention is simple, easy to realize and high in production efficiency.

2.本发明中的紫草膏制备过程经增加芝麻油作为主要成分,使得紫草膏富含大量人体必需的脂肪酸,亚油酸,经过反复过滤、浸泡后保留了各种中草药的有效成分,通过增强皮肤自身代谢来改善皮肤问题,安全有效,持续性更长久。2. The preparation process of the comfrey paste in the present invention increases sesame oil as the main component, so that the comfrey paste is rich in a large amount of essential fatty acids, linoleic acid, and after repeated filtration and soaking, the active ingredients of various Chinese herbal medicines are retained. Enhance the skin's own metabolism to improve skin problems, safe and effective, and last longer.

具体实施方式Detailed ways

下面结合实施例对本发明的发明内容作进一步地说明。The content of the present invention will be further described below in conjunction with the embodiments.

实施例1Example 1

一种紫草膏,以质量份数计算包括如下组份:紫草10份、松针6份、月见草6份、金银花6份、艾叶6份、当归6份、防风6份、地黄6份、白芷6份、乳香6份、没药6份、甘草6份、薄荷叶6份、蜂蜡60份、茶树精油0.5份、芝麻油280份。A comfrey paste, comprising the following components in parts by mass: 10 parts of comfrey, 6 parts of pine needles, 6 parts of evening primrose, 6 parts of honeysuckle, 6 parts of mugwort leaves, 6 parts of angelica, 6 parts of windproof, and 6 parts of rehmannia glutinosa , 6 parts of Angelica dahurica, 6 parts of frankincense, 6 parts of myrrh, 6 parts of licorice, 6 parts of mint leaves, 60 parts of beeswax, 0.5 parts of tea tree essential oil, 280 parts of sesame oil.

所述的紫草膏的制备方法,包括如下步骤:The preparation method of described comfrey paste, comprises the steps:

(1) 将上述质量组分的紫草、松针、月见草、薄荷叶、金银花,粉碎并混合,粉碎后各组分的粉碎粒径为60目,然后将上述各组分置于280份芝麻油中浸泡,浸泡条件为60℃下浸泡3天,制得浸油Ⅰ;所述过滤使用的筛网为100目;(1) Pulverize and mix the comfrey, pine needles, evening primrose, mint leaves, and honeysuckle of the above-mentioned quality components. Soak in sesame oil, the soaking condition is 3 days at 60°C to make immersion oil I; the sieve used for the filtration is 100 mesh;

(2) 将上述质量组分的当归、防风、地黄、白芷、乳香、没药、甘草,粉碎并混合,粉碎后各组分的粉碎粒径为50目,然后将其置于步骤(1)所得的浸油Ⅰ中浸泡,浸泡条件为60℃下浸泡3天,制取浸油Ⅱ;所述过滤使用的筛网为100目,(2) Grinding and mixing Angelica, Radix Rehmanniae, Angelica dahurica, Olibanum, Myrrha, and Glycyrrhizae of the above-mentioned quality components. Soak in the obtained immersion oil I, and the immersion condition is 3 days at 60° C. to prepare immersion oil II; the sieve used for the filtration is 100 mesh,

(3) 将60份蜂蜡置于步骤(2)制得的浸油Ⅱ中,加热至蜂蜡完全熔化;控制加热温度为80℃;(3) Place 60 parts of beeswax in the immersion oil II prepared in step (2), and heat until the beeswax is completely melted; control the heating temperature to 80°C;

(4) 将0.5份茶树精油加入步骤(3)所得产物,搅拌均匀,冷却至25℃后得成品。(4) Add 0.5 parts of tea tree essential oil to the product obtained in step (3), stir evenly, and cool to 25°C to obtain the finished product.

对所制得的紫草膏进行皮肤刺激性测试。The prepared comfrey paste was tested for skin irritation.

选择50名人员进行测试。其中,蚊虫叮咬患者30名、皮肤干燥患者10名、皮肤创伤者5名、麻疹患者5名。连续使用1周,每日使用2次。所有使用人员反映,其自身相应症状得到改善,无过敏现象和刺激性反应,性质温和,安全性好,且使用周期长,表明本发明的紫草膏对人体皮肤无刺激性,可适用于各类人群。50 persons are selected for testing. Among them, there were 30 patients with mosquito bites, 10 patients with dry skin, 5 patients with skin trauma, and 5 patients with measles. Use continuously for 1 week, 2 times a day. All users reported that their own corresponding symptoms were improved, without allergic phenomena and irritating reactions, mild in nature, good in safety, and long in service life, indicating that the comfrey paste of the present invention is non-irritating to human skin, and can be applied to various class crowd.

实施例2Example 2

一种紫草膏,以质量份数计算包括如下组份:紫草12份、松针6份、月见草8份、金银花8份、艾叶8份、当归8份、防风8份、地黄8份、白芷8份、乳香8份、没药8份、甘草8份、薄荷叶8份、蜂蜡65份、茶树精油0.7份、芝麻油310份。A comfrey paste, comprising the following components in terms of mass parts: 12 parts of comfrey, 6 parts of pine needles, 8 parts of evening primrose, 8 parts of honeysuckle, 8 parts of mugwort leaves, 8 parts of angelica, 8 parts of windproof, and 8 parts of rehmannia glutinosa , 8 parts of Angelica dahurica, 8 parts of frankincense, 8 parts of myrrh, 8 parts of licorice, 8 parts of mint leaves, 65 parts of beeswax, 0.7 parts of tea tree essential oil, and 310 parts of sesame oil.

所述的紫草膏的制备方法,包括如下步骤:The preparation method of described comfrey paste, comprises the steps:

(1) 将上述质量组分的紫草、松针、月见草、薄荷叶、金银花,粉碎并混合,粉碎后各组分的粉碎粒径为80目,然后将上述各组分置于310份芝麻油中浸泡,浸泡条件为70℃下浸泡4天,制得浸油Ⅰ;所述过滤使用的筛网为150目;(1) Comfrey, pine needles, evening primrose, mint leaves, and honeysuckle of the above-mentioned quality components are pulverized and mixed. Immersion in sesame oil, the immersion condition is 4 days at 70°C to obtain immersion oil I; the sieve used for the filtration is 150 mesh;

(2) 将上述质量组分的当归、防风、地黄、白芷、乳香、没药、甘草,粉碎并混合,粉碎后各组分的粉碎粒径为60目,然后将其置于步骤(1)所得的浸油Ⅰ中浸泡,浸泡条件为70℃下浸泡4天,制取浸油Ⅱ;所述过滤使用的筛网为150目,(2) Angelica sinensis, Fangfeng, Rehmannia glutinosa, Angelica dahurica, frankincense, myrrh, and licorice of the above-mentioned quality components are pulverized and mixed. Soak in the obtained immersion oil I, and the immersion condition is 4 days at 70°C to prepare immersion oil II; the sieve used for the filtration is 150 mesh,

(3) 将65份蜂蜡置于步骤(2)制得的浸油Ⅱ中,加热至蜂蜡完全熔化;控制加热温度为85℃;(3) Place 65 parts of beeswax in the immersion oil II prepared in step (2), and heat until the beeswax is completely melted; control the heating temperature to 85°C;

(4) 将0.7份茶树精油加入步骤(3)所得产物,搅拌均匀,冷却至25℃后得成品。(4) Add 0.7 parts of tea tree essential oil to the product obtained in step (3), stir evenly, and cool to 25°C to obtain the finished product.

对所制得的紫草膏进行皮肤刺激性测试。The prepared comfrey paste was tested for skin irritation.

选择50名人员进行测试。其中,蚊虫叮咬患者20名、皮肤干燥患者30名、皮肤创伤者5名、麻疹患者5名。连续使用2周,每日使用2次。所有使用人员反映,其自身相应症状得到改善,无过敏现象和刺激性反应,性质温和,安全性好,且使用周期长,表明本发明的紫草膏对人体皮肤无刺激性,可适用于各类人群。50 persons are selected for testing. Among them, there were 20 patients with mosquito bites, 30 patients with dry skin, 5 patients with skin trauma, and 5 patients with measles. Use continuously for 2 weeks, 2 times a day. All users reported that their own corresponding symptoms were improved, without allergic phenomena and irritating reactions, mild in nature, good in safety, and long in service life, indicating that the comfrey paste of the present invention is non-irritating to human skin, and can be applied to various class crowd.

实施例3Example 3

一种紫草膏,以质量份数计算包括如下组份:紫草15份、松针9份、月见草9份、金银花9份、艾叶9份、当归9份、防风9份、地黄9份、白芷9份、乳香9份、没药9份、甘草9份、薄荷叶9份、蜂蜡65份、茶树精油1份、芝麻油350份。A comfrey paste, comprising the following components in parts by mass: 15 parts of comfrey, 9 parts of pine needles, 9 parts of evening primrose, 9 parts of honeysuckle, 9 parts of mugwort leaves, 9 parts of angelica, 9 parts of windproof, and 9 parts of rehmannia glutinosa , 9 parts of Angelica dahurica, 9 parts of frankincense, 9 parts of myrrh, 9 parts of licorice, 9 parts of mint leaves, 65 parts of beeswax, 1 part of tea tree essential oil, 350 parts of sesame oil.

所述的紫草膏的制备方法,包括如下步骤:The preparation method of described comfrey paste, comprises the steps:

(1) 将上述质量组分的紫草、松针、月见草、薄荷叶、金银花,粉碎并混合,粉碎后各组分的粉碎粒径为100目,然后将上述各组分置于350份芝麻油中浸泡,浸泡条件为80℃下浸泡5天,制得浸油Ⅰ;所述过滤使用的筛网为200目;(1) Pulverize and mix the comfrey, pine needles, evening primrose, mint leaves and honeysuckle of the above-mentioned quality components. Immersion in sesame oil, the immersion condition is 5 days at 80°C to obtain immersion oil I; the sieve used for the filtration is 200 mesh;

(2) 将上述质量组分的当归、防风、地黄、白芷、乳香、没药、甘草,粉碎并混合,粉碎后各组分的粉碎粒径为70目,然后将其置于步骤(1)所得的浸油Ⅰ中浸泡,浸泡条件为80℃下浸泡5天,制取浸油Ⅱ;所述过滤使用的筛网为200目,(2) Angelica sinensis, Fangfeng, Rehmannia glutinosa, Angelica dahurica, frankincense, myrrh, and licorice of the above-mentioned quality components are pulverized and mixed. Soak in the obtained immersion oil I, and the immersion condition is to soak for 5 days at 80°C to prepare immersion oil II; the sieve used for the filtration is 200 mesh,

(3) 将65份蜂蜡置于步骤(2)制得的浸油Ⅱ中,加热至蜂蜡完全熔化;控制加热温度为90℃;(3) Place 65 parts of beeswax in the immersion oil II prepared in step (2), and heat until the beeswax is completely melted; control the heating temperature to 90°C;

(4) 将1份茶树精油加入步骤(3)所得产物,搅拌均匀,冷却至25℃后得成品。(4) Add 1 part of tea tree essential oil to the product obtained in step (3), stir evenly, and cool to 25°C to obtain the finished product.

对所制得的紫草膏进行皮肤刺激性测试。The prepared comfrey paste was tested for skin irritation.

选择50名人员进行测试。其中,蚊虫叮咬患者30名、皮肤干燥患者20名、皮肤创伤者5名、麻疹患者5名。连续使用3周,每日使用2次。所有使用人员反映,其自身相应症状得到改善,无过敏现象和刺激性反应,性质温和,安全性好,且使用周期长,表明本发明的紫草膏对人体皮肤无刺激性,可适用于各类人群。50 persons are selected for testing. Among them, there were 30 patients with mosquito bites, 20 patients with dry skin, 5 patients with skin trauma, and 5 patients with measles. Use for 3 weeks, 2 times a day. All users reported that their own corresponding symptoms were improved, without allergic phenomena and irritating reactions, mild in nature, good in safety, and long in service life, indicating that the comfrey paste of the present invention is non-irritating to human skin, and can be applied to various class crowd.

以上所述的仅是本发明的优选实施方式,应当指出,对于本领域的普通技术人员来说,在不脱离本发明创造构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。The above is only the preferred embodiment of the present invention, it should be pointed out that for those skilled in the art, without departing from the inventive concept of the present invention, some modifications and improvements can also be made, and these all belong to the present invention. protection scope of the invention.

Claims (10)

1. a kind of zicao soft plaster, which is characterized in that it includes following component to be calculated with mass fraction:
10-15 parts of Asian puccoon, 6-9 parts of pine needle, 6-9 parts of oenothera biennis, 6-9 parts of honeysuckle, 6-9 parts of folium artemisiae argyi, 6-9 parts of Radix Angelicae Sinensis, windproof 6-9 Part, 6-9 parts of glutinous rehmannia, 6-9 parts of the root of Dahurain angelica, 6-9 parts of frankincense, 6-9 parts of myrrh, 6-9 parts of Radix Glycyrrhizae, 6-9 parts of dried peppermint leaf, 60-65 parts of beeswax, 0.5-1 parts of tea tree ethereal oil, 280-350 parts of vegetable oil.
2. zicao soft plaster according to claim 1, which is characterized in that the vegetable oil is sesame oil.
3. zicao soft plaster according to claim 2, which is characterized in that the sesame oil is cold rolling sesame oil.
4. the preparation method of zicao soft plaster described in claim 1, which is characterized in that include the following steps:
(1) component proportion described in claim 1 is pressed, Asian puccoon, pine needle, oenothera biennis, dried peppermint leaf, honeysuckle is weighed, crushes and mix It closes, is placed in vegetable oil and impregnates, filter, produce immersion oil I;The vegetable oil is cold rolling sesame oil;
(2) component proportion as described in claim 1 weighs Radix Angelicae Sinensis, windproof, glutinous rehmannia, the root of Dahurain angelica, frankincense, myrrh, Radix Glycyrrhizae, crushes It is placed in the immersion oil I obtained by step (1) and impregnates, filter, produce immersion oil II;
(3) beeswax is placed in immersion oil II made from step (2), is heated to beeswax by component proportion as described in claim 1 It is completely melt;
(4) tea tree ethereal oil is added step (3) products therefrom, stirred evenly by component proportion as described in claim 1, cooling Finished product is obtained afterwards.
5. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (1), Asian puccoon, pine needle, Oenothera biennis, dried peppermint leaf, honeysuckle powder particle diameter be 50-100 mesh.
6. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (1), soaking conditions are It is impregnated 3-5 days at 60-80 DEG C;It is 100-200 mesh to filter the sieve used.
7. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (2), Radix Angelicae Sinensis, it is windproof, Glutinous rehmannia, the root of Dahurain angelica, frankincense, myrrh, Radix Glycyrrhizae powder particle diameter be 50-70 mesh.
8. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (2), soaking conditions are It is impregnated 3-5 days at 60-80 DEG C;It is 100-200 mesh to filter the sieve used.
9. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (3), heating temperature is 80 -90℃。
10. the preparation method of zicao soft plaster according to claim 4, which is characterized in that in the step (4), cooling temperature It is 25 DEG C.
CN201810652389.6A 2018-06-22 2018-06-22 A kind of zicao soft plaster and preparation method thereof Pending CN108553543A (en)

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Application publication date: 20180921