CN108497186A - A kind of additive premix improving sow reproductive performance - Google Patents
A kind of additive premix improving sow reproductive performance Download PDFInfo
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- CN108497186A CN108497186A CN201810245740.XA CN201810245740A CN108497186A CN 108497186 A CN108497186 A CN 108497186A CN 201810245740 A CN201810245740 A CN 201810245740A CN 108497186 A CN108497186 A CN 108497186A
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- additive
- reproductive performance
- sow
- premix
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- 239000000654 additive Substances 0.000 title claims abstract description 47
- 230000000996 additive effect Effects 0.000 title claims abstract description 33
- 230000001850 reproductive effect Effects 0.000 title claims abstract description 31
- 239000000203 mixture Substances 0.000 claims abstract description 32
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 26
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 16
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 14
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 13
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 13
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 13
- 229940046009 vitamin E Drugs 0.000 claims abstract description 13
- 239000011709 vitamin E Substances 0.000 claims abstract description 13
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims abstract description 11
- 150000002515 isoflavone derivatives Chemical class 0.000 claims abstract description 11
- 235000008696 isoflavones Nutrition 0.000 claims abstract description 11
- PMVSDNDAUGGCCE-TYYBGVCCSA-L Ferrous fumarate Chemical compound [Fe+2].[O-]C(=O)\C=C\C([O-])=O PMVSDNDAUGGCCE-TYYBGVCCSA-L 0.000 claims abstract description 8
- 229960002685 biotin Drugs 0.000 claims abstract description 8
- 235000020958 biotin Nutrition 0.000 claims abstract description 8
- 239000011616 biotin Substances 0.000 claims abstract description 8
- 229960000225 ferrous fumarate Drugs 0.000 claims abstract description 8
- 235000002332 ferrous fumarate Nutrition 0.000 claims abstract description 8
- 239000011773 ferrous fumarate Substances 0.000 claims abstract description 8
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229960000304 folic acid Drugs 0.000 claims abstract description 7
- 235000019152 folic acid Nutrition 0.000 claims abstract description 7
- 239000011724 folic acid Substances 0.000 claims abstract description 7
- 239000004615 ingredient Substances 0.000 claims abstract description 3
- LCQLHJZYVOQKHU-VKHMYHEASA-N carglumic acid Chemical class NC(=O)N[C@H](C(O)=O)CCC(O)=O LCQLHJZYVOQKHU-VKHMYHEASA-N 0.000 claims description 12
- 229920002261 Corn starch Polymers 0.000 claims description 6
- 239000008120 corn starch Substances 0.000 claims description 6
- 229940099112 cornstarch Drugs 0.000 claims description 6
- 229910021536 Zeolite Inorganic materials 0.000 claims description 4
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 239000010457 zeolite Substances 0.000 claims description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 3
- 235000013312 flour Nutrition 0.000 claims description 3
- 240000007594 Oryza sativa Species 0.000 claims description 2
- 235000007164 Oryza sativa Nutrition 0.000 claims description 2
- 239000000440 bentonite Substances 0.000 claims description 2
- 229910000278 bentonite Inorganic materials 0.000 claims description 2
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 2
- 235000009566 rice Nutrition 0.000 claims description 2
- 235000015099 wheat brans Nutrition 0.000 claims description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- 239000012141 concentrate Substances 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 229960002598 fumaric acid Drugs 0.000 claims 1
- 235000011087 fumaric acid Nutrition 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 210000001161 mammalian embryo Anatomy 0.000 abstract description 5
- 210000002826 placenta Anatomy 0.000 abstract description 5
- ZQSIJRDFPHDXIC-UHFFFAOYSA-N daidzein Chemical compound C1=CC(O)=CC=C1C1=COC2=CC(O)=CC=C2C1=O ZQSIJRDFPHDXIC-UHFFFAOYSA-N 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 210000003754 fetus Anatomy 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 4
- 235000016709 nutrition Nutrition 0.000 abstract description 3
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- 230000003169 placental effect Effects 0.000 abstract description 3
- 208000035752 Live birth Diseases 0.000 abstract description 2
- 230000000975 bioactive effect Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 238000012360 testing method Methods 0.000 description 7
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000011161 development Methods 0.000 description 4
- 230000018109 developmental process Effects 0.000 description 4
- 229940002061 ferrous fumarate 300 mg Drugs 0.000 description 4
- 229940083563 folic acid 1 mg Drugs 0.000 description 4
- 238000003786 synthesis reaction Methods 0.000 description 4
- 239000004475 Arginine Substances 0.000 description 3
- 239000003963 antioxidant agent Substances 0.000 description 3
- 230000003078 antioxidant effect Effects 0.000 description 3
- 235000006708 antioxidants Nutrition 0.000 description 3
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
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- 238000004519 manufacturing process Methods 0.000 description 3
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- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 2
- 235000014590 basal diet Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 229940037750 biotin 0.8 mg Drugs 0.000 description 2
- 229940046414 biotin 1 mg Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229940095463 folic acid 0.5 mg Drugs 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 230000006651 lactation Effects 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- IHHWIRIIIZBIDV-UHFFFAOYSA-N 4,5-dihydroxy-3-phenylchromen-2-one Chemical compound OC=1C=2C(O)=CC=CC=2OC(=O)C=1C1=CC=CC=C1 IHHWIRIIIZBIDV-UHFFFAOYSA-N 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 description 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 1
- 241000186660 Lactobacillus Species 0.000 description 1
- 241000218588 Lactobacillus rhamnosus Species 0.000 description 1
- 102000003960 Ligases Human genes 0.000 description 1
- 108090000364 Ligases Proteins 0.000 description 1
- 231100000678 Mycotoxin Toxicity 0.000 description 1
- RFMMMVDNIPUKGG-YFKPBYRVSA-N N-acetyl-L-glutamic acid Chemical class CC(=O)N[C@H](C(O)=O)CCC(O)=O RFMMMVDNIPUKGG-YFKPBYRVSA-N 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 1
- 208000021017 Weight Gain Diseases 0.000 description 1
- 230000003281 allosteric effect Effects 0.000 description 1
- 230000037354 amino acid metabolism Effects 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000003026 anti-oxygenic effect Effects 0.000 description 1
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- 238000013459 approach Methods 0.000 description 1
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- 239000003054 catalyst Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- 229940046374 chromium picolinate Drugs 0.000 description 1
- GJYSUGXFENSLOO-UHFFFAOYSA-N chromium;pyridine-2-carboxylic acid Chemical compound [Cr].OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1.OC(=O)C1=CC=CC=N1 GJYSUGXFENSLOO-UHFFFAOYSA-N 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 230000013020 embryo development Effects 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000006735 epoxidation reaction Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000004720 fertilization Effects 0.000 description 1
- 229940083565 folic acid 0.8 mg Drugs 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000037111 immune power Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 229940039696 lactobacillus Drugs 0.000 description 1
- 230000023247 mammary gland development Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000002636 mycotoxin Substances 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 230000009984 peri-natal effect Effects 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 description 1
- 150000008442 polyphenolic compounds Chemical group 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000004144 purine metabolism Effects 0.000 description 1
- 230000004147 pyrimidine metabolism Effects 0.000 description 1
- 238000007348 radical reaction Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- CEIZFXOZIQNICU-UHFFFAOYSA-N tenuazonic acid Chemical compound CCC(C)C1NC(=O)C(C(C)=O)=C1O CEIZFXOZIQNICU-UHFFFAOYSA-N 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 229960004295 valine Drugs 0.000 description 1
- 235000014393 valine Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/116—Heterocyclic compounds
- A23K20/121—Heterocyclic compounds containing oxygen or sulfur as hetero atom
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/30—Oligoelements
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of additive premixes improving sow reproductive performance, including carrier and compositions of additives, compositions of additives is by N carbamylglutamic acids, 4 ', 7 dihydroxy isoflavones, folic acid, vitamin E, biotin, ferrous fumarate composition, the additive amount of each ingredient is 1 20mg/kg of N carbamylglutamic acids, 4 ', 7 dihydroxy isoflavone, 8 50mg/kg, 0.5 1mg/kg of folic acid, 30 70mg/kg of vitamin E, 0.5 1mg/kg of biotin, 300 500mg/kg of ferrous fumarate in composition.The present invention also provides the additive application method simultaneously, and the composition being made of bioactive substance adds the additive premix being made of composition, than single any one single component of addition, effect is more preferable, to reduce the dosage of each additive, to cost-effective.Embryo, placenta, fetus can be developed using the additive premix in sow body and good nutrition assurance is provided, significantly improve sow nest farrowing sum, the number of live birth, it also improves to weigth at birth, nascent individual weight, Placental Weight, to be effectively improved the reproductive performance of sow.
Description
Technical field
The present invention relates to feedstuff additive premix compound technical fields, and in particular to a kind of addition improving sow reproductive performance
Agent premix.
Background technology
Sow breeding is the important link in pig production, directly affects pig farm weanling pig annual output, is to influence to support
The extremely important factor of pig industry economic benefit.The evaluation of sow reproductive performance includes litter size, year farrowing nest number, Birth weight, secretes
The content of four aspects of newborn power.The approach for improving sow reproductive performance also conducts a research mainly around these aspects, such as：Increase
Sow number of eggs ovulated；Breeding in due course improves the rate of fertilization of discharge ovum；Improve pregnant sow feeding management, improves survival rate of embryo；Contracting
Short farrowing internal increases nest number of farrowing in year；Appropriate exercise enhances sow constitution.These targets all must be corresponding by providing
Nutrition regulation measure is realized.Therefore, the research of the feed or additive premix to improving sow reproductive performance is just particularly heavy
Want meaning.
Patent application 201710442446.3 discloses a kind of feed addictive of milking sow, and composition includes plant
Lactobacillus metabolite antibacterial peptide, Lactobacillus rhamnosus, glucose oxidase, catalase, victory peptase, epoxidation reduction
Enzyme, phosphate etc..Its mechanism is to prevent mycotoxin and vivotoxin to the influence of milking sow, keeps milking sow immune
Power, lactation amount obviously increase, and weaned piglet significantly improves again.
Patent application 201711069021.9 discloses a kind of mixed feed improving sow reproductive performance, and composition includes
Vitamin, folic acid, biotin, Valine, chromium picolinate, dihydropyridine, chlorogenic acid etc..Its mechanism of action is enhancing sow
Resistance, be conducive to improve sow pregnancy rate and farrowing quantity, and improve young baby survival rate.
Invention content
The technical problems to be solved by the invention provide a kind of additive premix improving sow reproductive performance, the addition
Agent premix is the application technology of a set of synthesis, is developed in sow body to embryo, placenta, fetus and provides good nutrition guarantor
Barrier improves sow antioxygenic property, improves sow milk performance.To achieve the purpose that improve sow reproductive performance.
To solve the above problems, a kind of additive premix improving sow reproductive performance provided by the invention, including carry
Body and compositions of additives, the compositions of additives are given birth to by N- carbamylglutamic acids, 4',7-Dihydroxy-isoflavone, folic acid, dimension
Plain E, biotin, ferrous fumarate composition.
Carrier of the present invention be mountain flour, zeolite powder, bentonite, wheat bran, cornstarch or defatted rice bran in one kind or
Several mixing.
The additive amount of each ingredient is N- carbamylglutamic acids 1-20mg/kg, 4 ', 7- in compositions of additives of the present invention
Dihydroxy isoflavone 8-50mg/kg, folic acid 0.5-1mg/kg, vitamin E 30-70mg/kg, biotin 0.5-1mg/kg, rich horse
Sour ferrous iron 300-500mg/kg.
N- carbamylglutamic acids in the present invention are the analogues of N-acetylglutamat, the former can become instead of the latter
The allosteric catalyst of carbamylphosphate synthetase, to promote proline and glutamine to citrulling and conversion of Arginine,
Increase the endogenous synthesis of arginine, and arginine plays an important role the development of embryo, placenta and fetus.
Perinatal period and lactation period sow body influence its milk performance by serious oxidative stress.Therefore, body antioxygen
Change is also to improve sow reproductive performance to solve the problems, such as.It is Polyphenols object to add 4 ', 7- dihydroxy isoflavones in the present invention
Matter can be allowed to generate corresponding ion and molecule in vivo and in vitro with radical reaction, can inhibit the generation of free radical, remove,
Extinguish free radical, terminates the chain reaction of free radical, can promote the secretion of antioxidase, anti-lipid peroxidation that mother can be improved
The proliferation of pig galactophore epithelial cell reduces Apoptosis, so as to improve sow mammogenesis and antioxidant ability of organism, improves and feeds
Suckling piglet body weight gains and survival rate.
The effective antioxidant of vitamin E, it is the important component of tissue and cellular anti-oxidant system of defense.Folic acid
Purine, pyrimidine and amino acid metabolism process are participated in, to promote the synthesis of sow embryo DNA, RNA and various protein, directly
Influence the growth and development of embry ogenesis and fetus.Biotin participates in a variety of main metabolic processes as a kind of coenzyme, can
Energy is frustrated in the breeding for improving sow, reduces sow frequency of disease development.
Ferrous fumarate is a kind of organic source of iron, can pass to piglet by sow placenta and sow.To promote piglet
Growth and development prevents hypoferric anemia, reduces the sucking pig death rate.
The application method of the additive premix provided by the invention for improving sow reproductive performance, respectively according to 25-50kg/
Ton, 5-10kg/ tons, 1-2kg/ tons of ratio is added separately in 4% premix, 10% concentrated feed and perfect compound feed
.
Advantages of the present invention and advantageous effect：The composition being made of bioactive substance, effect is not each component
Simple superposition, but its each component acts synergistically, and is the application technology of a set of synthesis, the additive added with composition premixes
Material, than single any one single component of addition, effect is more preferable, reduces the dosage of each additive, to cost-effective.
Specific implementation mode
Being exemplified below specific embodiment, the present invention will be described, and embodiment is served only for that the invention will be further described,
Protection scope of the present invention is not represented, the nonessential modification and adjustment that other people make according to the present invention still fall within the present invention
Protection domain.
Embodiment 1
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 5mg/kg, 4 ', 7- dihydroxy isoflavones 10mg/kg, folic acid 0.5mg/kg, vitamin E 30mg/kg, biology
Plain 1mg/kg, ferrous fumarate 300mg/kg, carrier are zeolite powder, are uniformly mixed, the ratio according to 2kg/ tons is added to full price
In mixed feed.
Embodiment 2
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 10mg/kg, 4 ', 7- dihydroxy isoflavones 8mg/kg, folic acid 0.8mg/kg, vitamin E 70mg/kg, biology
Plain 0.5mg/kg, ferrous fumarate 500mg/kg, carrier are cornstarch, are uniformly mixed, are added to according to 40kg/ tons of ratio
In 4% premix.
Embodiment 3
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 20mg/kg, 4 ', 7- dihydroxy isoflavones 5mg/kg, folic acid 1mg/kg, vitamin E 60mg/kg, biotin
0.8mg/kg, ferrous fumarate 400mg/kg, carrier are mountain flour, are uniformly mixed, it is dense to be added to 10% according to 10kg/ tons of ratio
In contracting feed.
Embodiment 4
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 5mg/kg, 4 ', 7- dihydroxy isoflavones 50mg/kg, folic acid 1mg/kg, vitamin E 60mg/kg, biotin
1mg/kg, ferrous fumarate 300mg/kg, carrier are zeolite powder, are uniformly mixed, are added to full price according to 1kg/ tons of ratio and match
It closes in feed.
Embodiment 5
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 20mg/kg, 4 ', 7- dihydroxy isoflavones 5mg/kg, folic acid 1mg/kg, vitamin E 60mg/kg, biotin
0.8mg/kg, ferrous fumarate 400mg/kg, carrier are cornstarch, are uniformly mixed, are added to according to 10kg/ tons of ratio
In 4% premix.
Embodiment 6
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 5mg/kg, 4 ', 7- dihydroxy isoflavones 50mg/kg, folic acid 1mg/kg, vitamin E 60mg/kg, biotin
1mg/kg, ferrous fumarate 300mg/kg, carrier are cornstarch, are uniformly mixed, the ratio according to 1kg/ tons is added to full price
In mixed feed.
Embodiment 7
A kind of raising sow reproductive performance additive premix, including carrier and compositions of additives, in its composition, N-
Carbamylglutamic acid 15mg/kg, 4 ', 7- dihydroxy isoflavones 40mg/kg, folic acid 0.5mg/kg, vitamin E 60mg/kg, life
Object element 1mg/kg, ferrous fumarate 300mg/kg, carrier are cornstarch, are uniformly mixed, the ratio according to 5kg/ tons is added to
In 4% concentrated feed.
Application Example
Test site is certain pig farm of Nanning, selects that kind is consistent, long similar in body condition × big, primiparity pregnant sow
80, it is divided into control group and experimental group immediately within 60 days after being pregnent, each organizes 40 sows, each organizes 10 repetitions, it is each to repeat 4
Sow is designed using single factor experiment, feeds basal diet (control group) respectively and basal diet+4% improves sow reproductive ability
Energy additive premix (test group), test pig environmental condition is consistent, sow free water, and routinely health care is immunized and carries out
The sanitation and hygiene of environment.
The index determining of sow reproductive performance includes mainly：Record total young, the living young number of nest production, weigth at birth, nascent individual
Weight, data analysing method and processing method generally in the art.
Contrast groups and the result of total young, the living young number of test group nest production, weigth at birth, individual weight of coming into being, placenta see the table below：
| Control group | Test group | |
| Test sow number (head) | 40 | 40 |
| Litter size (head) | 11.53b | 12.64a |
| Son's number (head) living | 11.2b | 12.5a |
| Weigth at birth (kilogram) | 14.35 | 14.75 |
| Nascent individual weight (kilogram) | 1.25 | 1.39 |
| Placental Weight (kilogram) | 2.15 | 2.23 |
Note：Colleague's data shoulder not marking-up matrix shows that difference significantly (P ＞ 0.05), does not mark different lowercase letter indication differences
Significantly (P ＜ 0.05)
As can be seen from the table：Test group can significantly improve sow nest farrowing sum, the number of live birth, litter size and work
Young number improves 1 or more, and difference is extremely significantly (P ＜ 0.01).Also have centainly in weigth at birth, nascent individual weight, Placental Weight
It improves, but difference is not notable.Raising sow reproductive performance additive premix feeding disclosed by the invention has sow reproductive performance
Apparent improvement.
Claims (6)
1. a kind of additive premix improving sow reproductive performance, including carrier and compositions of additives, it is characterised in that：Institute
It is sub- by N- carbamylglutamic acids, 4 ', 7- dihydroxy isoflavones, folic acid, vitamin E, biotin, fumaric acid to state compositions of additives
Iron forms.
2. the additive premix according to claim 1 for improving sow reproductive performance, it is characterised in that：The carrier is
One or more of mountain flour, zeolite powder, bentonite, wheat bran, cornstarch or defatted rice bran mix.
3. the additive premix according to claim 1 for improving sow reproductive performance, it is characterised in that：The additive
The additive amount of each ingredient is N- carbamylglutamic acids 1-20mg/kg, 4 ', 7- dihydroxy isoflavones 8-50mg/kg, leaf in composition
Sour 0.5-1mg/kg, vitamin E 30-70mg/kg, biotin 0.5-1mg/kg, ferrous fumarate 300-500mg/kg.
4. the additive premix according to claim 1 or 2 or 3 for improving sow reproductive performance, it is characterised in that：It is described
Premix made an addition in 4% premix according to 25-50kg/ tons of ratio.
5. the additive premix according to claim 1 or 2 or 3 for improving sow reproductive performance, it is characterised in that：It is described
Premix made an addition in 10% concentrate feed according to 5-10kg/ tons of ratio.
6. the additive premix according to claim 1 or 2 or 3 for improving sow reproductive performance, it is characterised in that：It is described
Premix made an addition in complete feed according to 1-2kg/ tons of ratio.
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|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109221706A (en) * | 2018-09-20 | 2019-01-18 | 广东新南都饲料科技有限公司 | A kind of additive premix improving sow milk performance |
| CN112136980A (en) * | 2020-10-14 | 2020-12-29 | 广东省农业科学院动物科学研究所 | An additive premix for improving sow production performance |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101759603A (en) * | 2010-01-08 | 2010-06-30 | 中国科学院亚热带农业生态研究所 | Preparation method and application of feed additive N-carbamylglutamic acid |
| CN101953430A (en) * | 2010-07-15 | 2011-01-26 | 北京龙科方舟生物工程技术中心 | Feed, preparation method and use thereof in improvement in reproductive performance of sows |
| CN102239973A (en) * | 2011-08-15 | 2011-11-16 | 赣州八维生物科技有限公司 | Additive used for nursing sows, preparation process and using method thereof |
| CN102630638A (en) * | 2012-05-10 | 2012-08-15 | 广东温氏食品集团有限公司 | Method for improving the reproductive performance of sows |
| CN103829084A (en) * | 2013-12-17 | 2014-06-04 | 四川农业大学 | Feed additive capable of promoting mammary gland development of replacement gilts and gestating sows |
| CN104824377A (en) * | 2015-05-27 | 2015-08-12 | 北京市农林科学院 | Heat-stress-resistant breeding promotion composite additive for sows |
| CN105029091A (en) * | 2015-08-26 | 2015-11-11 | 青岛大信饲料有限公司 | Compound feed capable of increasing effective litter size of sows |
-
2018
- 2018-03-23 CN CN201810245740.XA patent/CN108497186A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101759603A (en) * | 2010-01-08 | 2010-06-30 | 中国科学院亚热带农业生态研究所 | Preparation method and application of feed additive N-carbamylglutamic acid |
| CN101953430A (en) * | 2010-07-15 | 2011-01-26 | 北京龙科方舟生物工程技术中心 | Feed, preparation method and use thereof in improvement in reproductive performance of sows |
| CN102239973A (en) * | 2011-08-15 | 2011-11-16 | 赣州八维生物科技有限公司 | Additive used for nursing sows, preparation process and using method thereof |
| CN102630638A (en) * | 2012-05-10 | 2012-08-15 | 广东温氏食品集团有限公司 | Method for improving the reproductive performance of sows |
| CN103829084A (en) * | 2013-12-17 | 2014-06-04 | 四川农业大学 | Feed additive capable of promoting mammary gland development of replacement gilts and gestating sows |
| CN104824377A (en) * | 2015-05-27 | 2015-08-12 | 北京市农林科学院 | Heat-stress-resistant breeding promotion composite additive for sows |
| CN105029091A (en) * | 2015-08-26 | 2015-11-11 | 青岛大信饲料有限公司 | Compound feed capable of increasing effective litter size of sows |
Non-Patent Citations (4)
| Title |
|---|
| 刘根桃,等: "妊娠后期母猪饲喂大豆黄酮对泌乳性能及初乳中激素水平的影响", 《南京农业大学学报》 * |
| 包淋斌: "大豆素在猪养殖中应用 ", 《江西饲料》 * |
| 王继强，等: "改善母猪繁殖性能的营养调控措施", 《中国饲料》 * |
| 陈丰，等: "大豆异黄酮对哺乳母猪生产性能及抗氧化性能的影响", 《饲料博览》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109221706A (en) * | 2018-09-20 | 2019-01-18 | 广东新南都饲料科技有限公司 | A kind of additive premix improving sow milk performance |
| CN112136980A (en) * | 2020-10-14 | 2020-12-29 | 广东省农业科学院动物科学研究所 | An additive premix for improving sow production performance |
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