CN108451862A - A kind of facial cleanser and preparation method thereof containing sealwort with moisturizing repair function - Google Patents

Abstract

The invention discloses a facial cleanser containing sealwort and having the function of moisturizing and repairing, which is mainly prepared from the following raw materials in proportion by weight: 15-25 parts of sealwort extract; 12-15 parts of butanediol; 4-pentanediol 5 parts; 4‑5 parts of polymer hyaluronic acid; 25‑35 parts of amino acid foaming agent; 3‑5 parts of trehalose; 4‑5 parts of urea; 3‑4 parts of thickener; 22‑40 parts of water. This facial cleanser product has a clear and stable formula effect. It mainly uses the extract of Chinese medicine Rhizoma Polygonatum as a functional medicinal ingredient. Through the mutual compatibility of the above-mentioned ingredients, it has long-lasting moisturizing, cleansing, anti-inflammatory and skin repairing effects, and the effect is mild. Safe, suitable for all skin types, effectively overcome the unstable effect of natural skin care products, or the shortcomings of cleaning products made of pure chemical ingredients, such as high irritation and low safety factor, and expand the efficacy of Rhizoma Polygonatum for external use and its application in skin care Application value in the field of supplies. The invention also discloses a preparation method of a facial cleanser containing sealwort and having the function of moisturizing and repairing.

Description

A facial cleanser containing sealwort with moisturizing and repairing function and preparation method thereof

technical field

The invention belongs to the technical field of daily chemical cleaning products, in particular to a facial cleanser containing sealwort and having the function of moisturizing and repairing.

Background technique

With the improvement of living standards, people have higher and higher requirements for daily cleaning and skin care products. As a kind of facial cleansing product, facial cleanser should not only have basic facial cleansing functions, but also have the functions of supplementing nutrition and protecting the skin. However, most of the facial cleansers currently on the market do not have the tonic effect of whitening the skin and anti-inflammatory repair; the facial cleansers with the above-mentioned tonic effects are mostly made of a large amount of chemical substances, which are irritating to the skin. Adverse reactions such as skin allergies occur, causing great distress to users.

As a big country of traditional Chinese medicine, my country has rich resources of traditional Chinese medicine. Integrating traditional Chinese medicine into facial cleanser products to prepare mild and safe traditional Chinese medicine facial cleanser has become a popular trend in the preparation of facial cleanser today. For example, white perilla, angelica and other traditional Chinese medicines with whitening effect are used as raw materials to prepare facial cleanser with whitening effect.

Polygonatum, as a Chinese herbal medicine with the same source of medicine and food, is specifically the dried rhizome of Polygonatum kingia-num Col1. Sweet and flat in nature and flavor, it is a tonic product for nourishing qi and nourishing yin.

At the present stage, along with domestic and foreign studies on the efficacy of Polygonatum, a deeper understanding has been obtained and more and more attention has been paid. Polygonatum can improve symptoms such as fatigue, physical weakness, shortness of breath, and heart palpitations. It can also be used to treat coronary heart disease, diabetes, hyperlipidemia, hypotension, chronic bronchitis, drug poisoning deafness, leukopenia, ischemic stroke and other diseases. With the gradual deepening of the pharmacology, medicinal chemistry and clinical research of Polygonatum, the research on the active ingredients and active parts of Polygonatum plants has also been paid attention to by the research and development of new drugs. Modern pharmacological studies have shown that Rhizoma Polygonatum and its polysaccharides have extensive effects such as lowering blood pressure, anti-tumor, lowering blood lipids, regulating immunity, and improving memory, which provide reference for clinical drug use, development and utilization of Rhizoma Polygonatum.

However, there are very few studies on the external application of Rhizoma Polygonatum and Polygonatum polysaccharides. So far, there is no technical report on using Rhizoma Rhizoma Polygonatum as a unique traditional Chinese medicine raw material to prepare facial cleanser with moisturizing and repairing effects. The invention explores the efficacy of Rhizoma Polygonatum for external use, deeply explores and grasps the potential value of Rhizoma Rhizoma Rhizoma Polygonatum and its polysaccharides for external use, promotes the development of the industrial chain of Rhizoma Rhizoma Rhizoma Polygonatum, and fully exerts the curing effect of Rhizoma Rhizoma Polygonatum.

Contents of the invention

The object of the present invention is to provide a kind of facial cleanser containing Polygonatum and having moisturizing and repairing function which is good in use effect, safe and mild, and another object of the invention is to provide a preparation method of the facial cleanser.

In order to realize the above-mentioned purpose of the invention, the present invention provides the following technical solutions:

A facial cleanser containing Rhizoma Polygonatum with moisturizing and repairing functions, characterized in that it is prepared from Rhizoma Rhizoma Polygonatum extract and facial cleanser base at a ratio of 1:15-25 by weight; wherein, the facial cleanser base includes the following weight Raw material composition of parts ratio: 12-15 parts of butanediol; 4-5 parts of pentylene glycol; 4-5 parts of polymer hyaluronic acid; 25-35 parts of foaming agent; -5 parts; 3-4 parts of thickener; 30-40 parts of water.

According to the above technical solution, the present invention provides a Chinese herbal facial cleanser prepared by refluxing the Polygonatum extract, which is extracted from Polygonatum Chinese medicinal materials, and the above-mentioned facial cleanser matrix components according to the ratio of parts by weight.

The inventor's research found that the chemical components in Polygonatum Polysaccharides, steroidal saponins, flavonoids, amino acids, lignans and other medicinal ingredients that play an effective health care effect when taken internally, and its external use has antibacterial, bacteriostasis and skin repair. Nutrients can promote skin repair and delay aging. As a relatively high content component of sealwort, polysaccharide has the most significant functions of external antibacterial, antibacterial and promoting skin regeneration. The contents of the Polygonatum polysaccharide and other medicinal components in the Polygonatum extract obtained by subjecting the Polygonatum fresh slices to the specific reflux extraction process of the present invention are significantly increased.

And, when this Rhizoma Polygonatum extract and above-mentioned matrix component are formulated according to the above-mentioned specific ratio, the polysaccharides and amino acids in the Polygonatum extract and other medicinal ingredients can be combined with alcohols, amino acids and hyaluronic acids in the matrix component. The chemical matrix components show a good and significant blending and synergistic effect, so that the resulting Polygonatum facial cleanser product has a high appearance color and luster, a fine and smooth texture, and a fragrant smell. It also has long-lasting moisturizing properties, significant cleaning, anti-inflammatory and skin repair. effect. In addition, this facial cleanser product has a clear and stable formula effect. It mainly uses the extract of Rhizoma Polygonatum as a functional medicinal ingredient. The effect is mild and safe. It is suitable for use on various skin types and effectively overcomes the unstable effect of natural skin care products or the preparation of simple chemical ingredients. The cleaning and care products are highly irritating and have low safety factors.

Preferably, a facial cleanser containing Rhizoma Polygonatum and having a moisturizing and repairing function is prepared from Polygonatum extract and facial cleanser base at a ratio of 1:15 by weight; wherein, the facial cleanser base includes the following ingredients by weight: Raw material composition: 15 parts of butylene glycol; 5 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 35 parts of foaming agent; 5 parts of trehalose; 5 parts of urea; 3 parts of thickener; 30 parts of water.

The inventor's experimental research found that when the proportioning by weight of each raw material component of Polygonatum facial cleanser product is further preferred to the above-mentioned range, the appearance color of the facial cleanser product of the gained product is brighter, the color chroma is more attractive in appearance, and the milky quality that the product shows The structure is delicate and smooth.

Further, the Polygonatum extract is specifically prepared by the following method:

S1: take washed fresh Rhizoma Polygonatum, slice it, crush it, and pass it through a 20-80 mesh sieve to obtain Rhizoma Rhizoma Rhizome powder;

S2: Take the above-mentioned sealwort powder, mix it with water according to the ratio of material to liquid 1:10-20;

S3: The mixed Polygonatum powder is refluxed twice for 1-2 hours to obtain the Polygonatum extract.

The present invention deliberately selects fresh Rhizoma Polygonatum with the highest content of medicinal substances such as polysaccharides, steroidal saponins, flavonoids, amino acids, and lignans as the extraction raw material. The optimal limitation of water-mixed material-to-liquid ratio and reflux extraction time can significantly promote the release and extraction of active ingredients such as Polygonatum Polysaccharides with moisturizing, anti-inflammatory, antibacterial and skin repair functions, and improve the effective ingredients in Polygonatum Extract characterized by polysaccharide content Extract utilization.

Preferably, Polygonatum powder is passed through a 50-70 mesh sieve in step S1; the mixture ratio of Polygonatum powder and water in step S2 is 1:15; the extraction time of each reflux in step S3 is 1.5h.

Experimental research by the inventors shows that: when the above-mentioned Polygonatum reflux extraction process parameters are preferably controlled within the above-mentioned ranges, the extraction rate of Polygonatum polysaccharides can reach up to 10%, further improving the extraction and utilization efficiency of Polygonatum medicinal components.

Further, the foaming agent is an amino acid foaming agent, including one or more of ms-11 amino acid powder foaming agent and No. 2 amino acid foaming agent. More preferably, the ratio by weight of the ms-11 amino acid powder foaming agent and No. 2 amino acid foaming agent is 2-5:1-2.

Another object of the present invention is to provide a preparation method of the above-mentioned facial cleanser containing Polygonatum Polygonatum with moisturizing and repairing functions, so as to ensure the compatibility of each raw material component, make the product texture delicate and stable, and better exert the medicinal effects of Polygonatum Polysaccharides and the like After the compatibility of ingredients and various matrix ingredients, long-lasting moisturizing, cleaning, anti-inflammation and skin repair effects are exerted.

A preparation method of a facial cleanser containing sealwort and having a moisturizing and repairing function, comprising the steps of:

a. Raw material classification: Weigh foaming agent, butanediol and pentanediol and place them in container A, then weigh polymer hyaluronic acid, urea, trehalose, thickener and water and place them in container B;

b. Preheating treatment: Preheat the raw materials in the above-mentioned container A and container B to 80-90°C respectively;

c. Mixing and emulsification: Mix the preheated raw materials in container A and container B while stirring, and emulsify at 80-90°C for 10-20 minutes;

d. Adding Rhizoma Polygonatum Extract: Reduce the stirring speed, wait until the temperature drops to 60°C, add Rhizoma Rhizoma Polygonatum Water Extract according to the distribution ratio of the components, stir at a slow speed to 48°C, stop heating, wait for natural cooling to room temperature, and then bottle it. That is to say, the facial cleanser product containing the sealwort has a moisturizing and repairing function.

According to the above-mentioned technical scheme, in order to make the raw material components blend evenly, the present invention deliberately adopts the raw material classification and mixing method, by pre-mixing the amino acid foaming agent, butanediol and pentanediol in the oil phase in the facial cleanser base component, and The polymer hyaluronic acid, urea, trehalose, thickener and water in the water phase are preheated separately to 80-90°C, so that the matrix raw material components in the two phases can achieve Premixed effect. Then keep it at 80-90°C to fully mix and emulsify the two-phase matrix components to improve the fineness and smoothness of the final product. Then, keeping at 60°C, add the Polygonatum extract and mix, so that the medicinal ingredients in the Polygonatum extract and the matrix components are mixed and mixed with each other, and the fineness of the matrix texture is further promoted, and the medicinal ingredients such as Polygonatum polysaccharides are mixed with each other. After the synergistic compatibility of chemical components such as urea and polymer hyaluronic acid in the matrix, a facial cleanser product with longer moisturizing, anti-inflammatory and skin repair functions can be obtained.

Compared with prior art, the beneficial effect of the present invention:

1. The present invention finds that the sealwort extract can play a good compatibility with the specific matrix formula composed of butanediol, pentylene glycol, polymer hyaluronic acid, trehalose, thickener and water, and the two are in accordance with The facial cleanser product prepared according to the ratio ratio of the formula in the present invention has long-lasting moisturizing, cleansing, anti-inflammation and skin repairing effects, and further expands the external efficacy of Polygonatum medicinal material and its application in the field of toiletries.

2. The present invention successfully overcomes the defect that the extraction rate is not high in the existing Polygonatum reflux extraction method by optimizing the process parameters in the Polygonatum reflux extraction method, greatly improves the full extraction utilization rate of Polygonatum raw medicinal materials, and reduces the preparation of Polygonatum facial cleanser products Cost, high practical value of industrialization.

3. The facial cleanser product with moisturizing and repairing functions containing Polygonatum described in the present invention has a clear and stable formula effect, and is mild and safe. It is suitable for use on various skin types and can effectively overcome the unstable effect of natural skin care products, or cleansers prepared with pure chemical ingredients. However, the protective products are highly irritating and have low safety factors.

Description of drawings:

Figure 1 shows the effect of solid-liquid ratio on the extraction of Polygonatum Polysaccharides.

Figure 2 shows the effect of Polygonatum pulverized particle size on the extraction rate of Polygonatum polysaccharide.

Figure 3 shows the effect of extraction time on the extraction rate of Polygonatum polysaccharide.

Fig. 4 is the physical photograph of the Polygonatum facial cleanser product prepared according to the matrix formula of Experiment No. 1 in Comparative Test Example 1.

Fig. 5 is the physical photograph of the Polygonatum facial cleanser product prepared according to the matrix formula of Experiment No. 2 in Comparative Test Example 1.

Fig. 6 is the photo of the physical product of Polygonatum facial cleanser prepared according to the base formula of Experiment No. 3 in Comparative Test Example 1.

Fig. 7 is the physical photograph of the Polygonatum facial cleansing milk product prepared according to the base formula of Experiment No. 4 in Comparative Test Example 1.

Fig. 8 is a photograph of the physical product of Polygonatum facial cleanser prepared according to the matrix formula of Experiment No. 5 in Comparative Test Example 1.

Detailed ways

The present invention will be further described in detail below in conjunction with test examples and specific embodiments. However, it should not be understood that the scope of the above subject matter of the present invention is limited to the following embodiments, and all technologies realized based on the content of the present invention belong to the scope of the present invention.

Example 1

A facial cleanser containing Rhizoma Polygonatum with moisturizing and repairing functions, which is prepared from Polygonatum extract and facial cleanser base at a ratio of 1:15 by weight; wherein, the facial cleanser base includes the following ingredients by weight : 15 parts of butylene glycol; 5 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 25 parts of ms-11 amino acid powder foaming agent; 10 parts of amino acid foaming agent No. 2; 5 parts of trehalose; 5 parts of urea; 2 parts of cleansing cream thickener No. 1; 1 part of cleansing cream thickener No. 2; 30 parts of water. Its preparation method is as follows:

1, the preparation of Rhizoma Polygonati extract: the fresh Rhizoma Rhizoma Polygonatum of cleaning, after sectioning, pulverizes, crosses 60 mesh sieves, obtains the ^{Rhizoma Rhizoma Polygonatum} powder that particle size is about 0.5cm . Then mix the above-mentioned Rhizoma Polygonatum powder with water according to the ratio of solid to liquid at 1:15, place it in a reflux extractor, and extract it twice with reflux, each time for 1.5 hours, to obtain and reflux the extract, which is the Rhizoma Polygonatum extract.

2. Classification and preheating of matrix raw material components: Weigh the amino acid foaming agent, butanediol and pentanediol in the proportion by weight and place them in container A, and then weigh the polymer hyaluronic acid in the proportion by weight Acid, urea, trehalose, thickener and water are placed in container B; then the raw materials in container A and container B are preheated to 85°C respectively;

3. Mixing and emulsification of matrix components: mix the preheated raw materials in container A and container B while stirring, and emulsify at 85°C for 10 minutes;

4. Adding Rhizoma Polygonatum Extract: Reduce the stirring speed, wait until the temperature drops to 60°C, add Rhizoma Rhizoma Polygonatum Water Extract according to the distribution ratio of the components, stir evenly at a slow speed to 48°C, stop heating, and wait for natural cooling to room temperature before bottling. That is to say, the facial cleanser product containing the sealwort has a moisturizing and repairing function.

Example 2

A facial cleanser containing Rhizoma Polygonatum with moisturizing and repairing functions, which is prepared from Polygonatum extract and facial cleanser base at a ratio of 1:20 by weight; wherein, the facial cleanser base includes the following ingredients by weight : 12 parts of butanediol; 54 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 20 parts of ms-11 amino acid powder foaming agent; 5 parts of amino acid foaming agent No. 2; 3 parts of trehalose; 4 parts of urea; 1 part of cleansing cream thickener No. 1; 12 parts of cleansing cream thickener No. 2; 22 parts of water. Its preparation method is as follows:

1, the preparation of Rhizoma Polygonatum extract: the fresh Rhizoma Rhizoma Polygonatum of cleaning, cross 70 mesh sieves after pulverizing after the section, obtain the Rhizoma Rhizoma Polygonatum powder that particle size is about ^0.4cm . Then mix the above-mentioned Rhizoma Polygonatum powder with water according to the ratio of solid to liquid at 1:20, put it in a reflux extractor, and reflux and extract twice for 2 hours each time to obtain and reflux the extract, which is the Rhizoma Polygonatum extract.

2. Classification and preheating of matrix raw material components: Weigh the amino acid foaming agent, butanediol and pentanediol in the proportion by weight and place them in container A, and then weigh the polymer hyaluronic acid in the proportion by weight Acid, urea, trehalose, thickener and water are placed in container B; then the raw materials in container A and container B are preheated to 80°C respectively;

3. Mixing and emulsification of matrix components: mix the preheated raw materials in container A and container B while stirring, and keep emulsified at 80°C for 20 minutes;

4. Adding Rhizoma Polygonatum Extract: Reduce the stirring speed, wait until the temperature drops to 60°C, add Rhizoma Rhizoma Polygonatum Water Extract according to the distribution ratio of the components, stir evenly at a slow speed to 48°C, stop heating, and wait for natural cooling to room temperature before bottling. That is to say, the facial cleanser product containing the sealwort has a moisturizing and repairing function.

Example 3

A facial cleanser containing Rhizoma Polygonatum with moisturizing and repairing functions, which is prepared from Rhizoma Rhizoma Polygonatum extract and facial cleanser base at a ratio of 1:25 by weight; wherein, the facial cleanser base includes the following ingredients by weight : 15 parts of butanediol; 5 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 20 parts of ms-11 amino acid powder foaming agent; 10 parts of amino acid foaming agent No. 2; 5 parts of trehalose; 5 parts of urea; 3 parts of thickener; 30 parts of water. Its preparation method is as follows:

1, the preparation of Rhizoma Polygonatum extract: the fresh Rhizoma Rhizoma Rhizoma Polygonatum of washing, after sectioning, pulverizes, crosses 50 mesh sieves, obtains the ^Rhizoma Rhizoma Polygonatum powder that particle size is about 0.6cm . Then mix the above-mentioned Rhizoma Polygonatum powder with water according to the ratio of material to liquid 1:10, place it in a reflux extractor, and extract it twice by reflux, each time for 1 hour, to obtain and reflux the extract, which is the Rhizoma Polygonatum extract.

2. Classification and preheating of matrix raw material components: Weigh the amino acid foaming agent, butanediol and pentanediol in the proportion by weight and place them in container A, and then weigh the polymer hyaluronic acid in the proportion by weight Acid, urea, trehalose, thickener and water are placed in container B; then the above-mentioned raw materials in container A and container B are preheated to 90°C respectively;

3. Mixing and emulsification of matrix components: mix the preheated raw materials in container A and container B while stirring, and emulsify at 90°C for 10-20 minutes;

4. Adding Rhizoma Polygonatum Extract: Reduce the stirring speed, wait until the temperature drops to 60°C, add Rhizoma Rhizoma Polygonatum Water Extract according to the distribution ratio of the components, stir evenly at a slow speed to 48°C, stop heating, and wait for natural cooling to room temperature before bottling. That is to say, the facial cleanser product containing the sealwort has a moisturizing and repairing function.

Comparative example 1

A facial cleanser, which is prepared from Polygonatum extract and a facial cleanser base in a ratio of 1:10 by weight; wherein, the facial cleanser base includes the following raw materials in a weight ratio: 12 parts of butanediol; 54 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 20 parts of ms-11 amino acid powder foaming agent; 5 parts of amino acid foaming agent No. 2; 3 parts of trehalose; 4 parts of urea; cleansing cream thickener No. 1 1 part; cleansing cream thickener No. 2 12 parts; water 22 parts. Its preparation method is with embodiment 1.

Comparative example 2

A facial cleanser, which is prepared from Polygonatum extract and a facial cleanser base in a ratio of 1:30 by weight; wherein, the facial cleanser base includes the following raw materials in a weight ratio: 12 parts of butanediol; 54 parts of pentylene glycol; 20 parts of ms-11 amino acid powder foaming agent; 5 parts of amino acid foaming agent No. 2; 3 parts of trehalose; 4 parts of urea; 1 part of cleansing cream thickener No. 1; cleansing cream thickener No. 2, 12 parts; water, 22 parts. Its preparation method is with embodiment 1.

Comparative example 3

This comparative example is set with respect to embodiment 1, and its difference with embodiment 1 is: omit the operation of classifying and preheating mixing of each raw material component in embodiment 1 and adding the Polygonatum extract step by step, and change the described each raw material component by After weighing the proportioning relationship in parts by weight, heat, mix and emulsify together. details as follows:

A facial cleanser, which is prepared from Polygonatum extract and facial cleanser base at a weight ratio of 1:15; wherein, the facial cleanser base includes the following raw materials in a weight ratio: 15 parts of butanediol; 5 parts of pentylene glycol; 5 parts of polymer hyaluronic acid; 25 parts of ms-11 amino acid powder foaming agent; 10 parts of amino acid foaming agent No. 2; 5 parts of trehalose; 5 parts of urea; cleansing cream thickener No. 1 2 parts; 1 part of cleansing cream thickener No. 2; 30 parts of water. Its preparation method is as follows:

1, the preparation of Rhizoma Polygonatum extract: the fresh Rhizoma Rhizoma Polygonatum of cleaning, cross 60 mesh sieves after pulverizing after the section, obtain the Rhizoma Rhizoma Polygonatum powder that particle size is about ^0.5cm . Then mix the above-mentioned Rhizoma Polygonatum powder with water according to the ratio of solid to liquid at 1:15, place it in a reflux extractor, and extract it twice with reflux, each time for 1.5 hours, to obtain and reflux the extract, which is the Rhizoma Polygonatum extract.

2. Heating and mixing of raw materials: According to the ratio of the above-mentioned parts by weight, weigh all the above-mentioned raw material components, and then add them to the container together, heat to 85°C, stir and mix, and keep emulsified at 85°C for 10 minutes;

3. After being naturally cooled to room temperature, bottle it to obtain the facial cleanser product with moisturizing and repairing functions containing Polygonatum.

Comparative test example 1

Effects of different base formula components on the texture properties of Polygonatum facial cleanser

In this test example, 5 groups of different matrix formula experimental groups as shown in Table 1 are set, and with reference to the preparation method described in Example 1, each matrix formula in Table 1 is extracted with Polygonatum in weight proportions described in Example 1 Liquid compatibility, the product as shown in Figure 4-Figure 8 is prepared. And by observing the appearance and physical properties of each product, the impact of different matrix formula components on the texture properties of Polygonatum facial cleanser products was determined.

Table 1 Five kinds of different matrix prescription experiment situation tables (weight parts)

According to the above-mentioned five matrix prescriptions, the products shown in Figure 4-Figure 8 were sequentially prepared. By observing the fineness and smoothness of the texture of the above-mentioned five matrix products, the stability of cold resistance and heat resistance, color, smell and other indicators, it was found that: according to 3 No. and No. 4 matrix formulas and Polygonatum extracts in a fixed weight ratio are compatible to prepare facial cleansers (No. 3 corresponds to Figure 6, and No. 4 corresponds to Figure 7). The appearance is more uniform in color, and the texture is relatively finer and smoother. , and was a delicate smell, all aspects of characteristics are significantly better than the other three. Among them, the facial cleanser product obtained according to the No. 3 base formula (as shown in Figure 6) is particularly preferred, the product has the highest smoothness and fine texture, and the best appearance characteristics.

Comparative test example 2

This group of comparative test examples adopts the phenol-sulfuric acid colorimetric method to measure the Polygonatum polysaccharide content in the Polygonatum extract obtained by each group of extraction processes in the following test examples, so as to determine the influence of each process parameter on the Polygonatum extraction rate in the Polygonatum reflux extraction process. The specific experimental method is as follows:

1. Establishment of glucose standard curve

Weigh Polygonatum slices, pulverize, sieve the powder, add 15 times the amount of water, reflux extraction twice, each time for 1.5h, take the filtrate, and concentrate. Add anhydrous ethanol equivalent to the concentrate to make the alcohol content of the filtrate reach 50%, so the polysaccharide in the filtrate can be precipitated. Refrigerate overnight, take the supernatant, centrifuge at 3000r/min for 10min, discard the precipitate, concentrate under reduced pressure in a rotary evaporator until there is no alcohol smell, then add 3 times the volume of absolute ethanol to precipitate Polygonatum Polysaccharide, and dry it at 40°C for storage. Weigh an appropriate amount of Polygonatum Polysaccharide, and dilute to 100mL with distilled water to make the test solution.

Then the above-mentioned need testing solution, reference solution and blank solution are compared one by one. Take the above-mentioned Polygonatum polysaccharide test solution, and measure 100 μg/mL glucose solution into a graduated test tube with precise gradient respectively, distill water to 2.0mL, add 1.0mL 5% phenol solution, mix well, then add 5.0mL 98% concentrated sulfuric acid, mix well. The color was developed at room temperature for 20 minutes, and the absorbance (A) was measured at a wavelength of 490 nm with a blank solution. Taking the absorbance A (Y) as the ordinate and the concentration of glucose μg/ml (X) as the abscissa to carry out regression processing, the regression equation is Y=7.1405X+0.1959, R ² =0.9993. There is a good linear relationship in the range of /ml, and the glucose detection standard curve was successfully established.

2. Effect of solid-liquid ratio on the extraction rate of Polygonatum polysaccharide

Take 5 equal parts of 100g washed Polygonatum slices, crush them to ^0.5cm2 particle size, and then add After the corresponding double amount of drinking water, the number of times of reflux extraction was unified twice, and under the condition of 1.5h for each reflux extraction, the filtrate obtained by reflux extraction of Polygonatum powder was concentrated, which was the extract of Polygonatum in each group. The absorbance of the polysaccharides in the extracts of Polygonatum extracts of each group was measured by the above-mentioned phenol-sulfuric acid colorimetric method, so as to determine the extraction rate of Polygonatum polysaccharides. The test results are shown in Figure 1.

According to Figure 1, it can be seen that with the change of the solid-liquid ratio, the extraction rate of Polygonatum Polysaccharide also changes to varying degrees. When the solid-liquid ratio of Polygonatum part and water is preferably controlled in the range of 1:10-20, the extraction rate of Polygonatum polysaccharide in the obtained Polygonatum extract is significantly higher than the extraction of Polygonatum polysaccharide in the Polygonatum extract described below in other solid-liquid ratios Rate. Particularly preferably, when the liquid ratio of Rhizoma Polygonatum powder and water mixture is controlled to be 1:15, the extraction rate of Polygonatum polysaccharide in the obtained extract is the highest.

3. The impact of Polygonatum pulverization particle size on the extraction rate of Polygonatum polysaccharide

Take 5 equal parts of washed Polygonatum slices 100g, crush them to 0.2cm ² , 0.4cm ² , 0.6cm ² , 0.8cm ² , 1.2cm ² in particle size respectively, and add them to drink according to the solid-liquid ratio of 1:15 After the water is mixed, the number of times of reflux extraction is 2 times, and the Polygonatum powder is extracted under the condition of reflux extraction for 1.5 hours each time. The Polygonatum extract obtained by refluxing and extracting Polygonatum powder with different particle sizes was used to measure the absorbance of polysaccharides in the Polygonatum extract of each group by the above-mentioned phenol-sulfuric acid colorimetric method, so as to determine the extraction rate of Polygonatum polysaccharide. The test results are shown in Figure 2.

The experimental results shown in Figure 2 show that the extraction rate of Polygonatum polysaccharide also varies to varying degrees with the variation of the crushed particle size. When the Rhizoma Polygonatum is preferably crushed to a particle size of 0.4-0.6 cm ² , the extraction rate of polysaccharides in the Rhizoma Polygonatum extract is significantly higher than that of other crushed particle sizes. It is particularly preferred that when the Polygonatum medicinal material is crushed to 0.5 cm ² , the polysaccharide extraction rate in the Polygonatum extract is the highest.

4. The influence of extraction time on the extraction rate of Polygonatum polysaccharide

Extraction time of 1.0, 1.5, 2.0h, solid-liquid ratio of 1:15, crushing particle size of 0.5cm ² , and extraction times of 2 times were used to extract Polygonatum powder. And adopt the phenol-sulfuric acid colorimetric method to measure the absorbance of the polysaccharide in Polygonatum extract obtained by reflux extraction of Polygonatum powder under different extraction time conditions, so as to determine the extraction rate of Polygonatum polysaccharide. The test results are shown in Figure 3.

According to the experimental results shown in Figure 3, it is shown that with the change of extraction time, the extraction rate of Polygonatum polysaccharide also changes to varying degrees. When the extraction time of each reflux is preferably controlled within 1-2 hours, the polysaccharide content in the resulting Polygonatum extract is relatively high. Particularly preferably, each time of reflux extraction for 1.5 hours, the polysaccharide content in the obtained Polygonatum extract significantly increases to about 12%, and the extraction utilization rate of Polygonatum medicinal material is the highest.

Comprehensively all the test results of this test example can be seen: in the process of preparing the raw material of Rhizoma Polygonatum extract, when fresh Rhizoma Rhizoma Polygonatum is carried out to clear water reflux extraction, the Rhizoma Rhizoma Polygonatum medicinal material is pulverized to 0.4-0.6cm ^Polygonatum powder, and the Rhizoma Polygonatum powder is mixed with clear water The ratio of solid to liquid is 10-20:1, 2 times of reflux extraction, under the process conditions of 1-2h for each reflux extraction, the extraction utilization rate of useful medicinal components such as polysaccharides in Rhizoma Polygonatum is relatively significantly improved. Particularly preferably, the Rhizoma Polygonatum medicinal material is pulverized to 0.5cm ^Polygonatum powder, the solid-liquid ratio of the Rhizoma Polygonatum powder mixed with clear water is 15:1, reflux extraction is carried out twice, under the process condition of each reflux extraction 1.5h, to Polysaccharides and other useful medicinal components in Polygonatum have the highest extraction utilization rate. Thereby effectively improve the raw material utilization rate of Polygonatum medicinal material in the preparation facial cleanser of the present invention, reduce the manufacturing raw material cost.

Comparative test example 3 Performance comparative test of Polygonatum facial cleanser product

Contrast test 3.1 pH contrast test

Principle: Weakly acidic skin is the foundation of healthy skin. The PH value of healthy oriental skin should be between 4.5-6.5, with an average of about 5.2. It is weakly acidic. If the PH value of facial cleanser is too low or too high, it will burn the skin Therefore, the national standard stipulates that the pH value of facial cleanser should be controlled at 4.5-8.5. Generally, the pH value of weakly acidic products is about ≥5.0 and ≤5.6. The pH value of weakly alkaline products is about ≤8.0, ≤8.5. The pH value of neutral products is about 7.0.

Evaluation method: Use a sterilized cotton swab to absorb a small amount of distilled water, then dip in about 0.5 grams of facial cleanser, apply it to the port of the pH meter, read the pH value of the facial cleanser, and record the results in turn. See Table 2.

Table 2 Experimental data records

Comparative test 3.2 Cleanliness comparative test

Principle: The main function of facial cleanser is to clean the skin. Therefore, whether the facial cleanser is good or not depends first on its cleaning ability. This evaluation will take the simplest method of hand skin scratches, and make a horizontal cleanliness comparison with different facial cleansers sold in the market. After cleaning, the cleanest hand scratches, the stronger the cleaning power, and vice versa. weaker.

Evaluation method: Use a colored pen to draw a straight line about two centimeters long with the same medium force on the skin of the back of the hand. The force is uniform, and the result of 10 scratches is the same. Then use the same amount of 1g of cleanser of each brand to clean the scratches respectively, gently knead for 20 seconds, observe the evaluation results, arrange them in order of cleanliness from small to large, and record them in turn. See Table 3.

Table 3 Experimental data records

Contrast Test 3.3 Comfort Contrast Test

Principle: Generally, when purchasing cleansing products, consumers will habitually open the bottle cap and squeeze out a little to see its color and texture. Due to the different substances such as oils, thickeners, curing agents, and surfactants contained in the product, the texture of facial cleanser can be divided into four categories: cream, gel, and mousse. This experiment will evaluate the product through comfort. The best quality facial cleanser should have a moderate color, if it is too dark, it will appear rough, and if it is too shiny, it will have more oil base. Less foam means insufficient cleansing power, and too much foam can cause dry skin. Therefore, after evaluating the color, texture, and richness of foam, it is concluded that the milky color should be milky white, and the milky texture feels mild and not greasy after touching. At the same time, the density should be moderate, not easy to condense into fast, the overall feeling is delicate, soft, shiny, soft texture, and the most comfortable feeling when it comes into contact with the skin

Evaluation method: From the color, texture, and richness of foam of facial cleanser milk as the main entry point to feel the comfort of the product, and record the results. See Table 4.

Table 4 Experimental data records

Contrast test 3.4 Contrast test of continuous moisturizing time, skin repair rate and antibacterial rate of products

Test objects: 250 people aged 18-40 who have skin allergies and damage symptoms to cosmetics in varying degrees.

Test method: According to the "Hygienic Standard for Cosmetics" (GB7918-87), 250 test subjects were randomly divided into 3 groups, recorded as test 1 group, test 2 group, test 3 group and test 4 group. Wherein, test 1 group uses commercially available common moisturizing repair facial cleanser; test 2 groups use the facial cleanser prepared by comparative example 1 (change the facial cleanser of product formula ratio); test 2 groups use the facial cleanser prepared by comparative example 2 (change product formula Proportional face cleanser); test 4 groups use the face cleanser prepared in comparative example 3 (change the face cleanser of preparation process step) test 5 groups use the face cleanser that contains sealwort prepared in embodiment 3 and has moisturizing repair function. The comparison test results of continuous moisturizing time, skin repair rate and antibacterial rate of different products are shown in Table 5 below:

Table 5 Contrast test results of continuous moisturizing time, skin repair rate and antibacterial rate of the product

It can be seen from Table 5 that the effect of the test group 2-test 5 is obviously better than that of the test group 1. In the test group 5, the moisturizing time was the longest, the total number of colonies was the least, the recovery rate of allergic skin was the highest, and the time for complete repair of allergic skin was the shortest.

Based on the performance comparison test results above, it can be seen that: (1) In terms of pH, the pH of Polygonatum Facial Cleanser is compatible with the pH of human facial skin. It has good mildness and will not cause any irritation to the skin after long-term use. (2) In the cleanliness test, the cleansing milk containing sealwort described in the present invention has a moderate cleansing ability, so it will not be able to remove the grease and dust on the skin due to insufficient cleaning ability during use, and at the same time, it will not be affected by the cleansing ability. If it is too strong, it will take away too much oil, making the facial skin dry, causing peeling, pain and other consequences; (3) In the evaluation of the comfort of facial cleanser, Huangjing facial cleanser is in the form of paste, which has the advantage of being easy to adjust for a single use; And the foaming ability is strong, and it has the advantages of thick and fine foam; its color and smell are not used in other facial cleansers added with essential oils, but have the medicinal fragrance of the pure natural, non-added traditional Chinese medicine Polygonatum itself.

Claims (10)

1. a kind of facial cleanser containing sealwort with moisturizing repair function, which is characterized in that by sealwort extracting solution and facial cleanser matrix, According to weight 1：15-25 is formulated；Wherein, the facial cleanser matrix includes the raw material group of following weight At：12-15 parts of butanediol；4-5 parts of pentanediol；4-5 parts of polymer hyaluronic acid；25-35 parts of foaming agent；3-5 parts of trehalose；Urine It is 4-5 parts plain；3-4 parts of thickener；30-40 parts of water.

2. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that its feature It is, by sealwort extracting solution and facial cleanser matrix, according to weight 1：15 are formulated；Wherein, the facial cleanser matrix, Raw material composition including following weight：15 parts of butanediol；5 parts of pentanediol；5 parts of polymer hyaluronic acid；Foaming agent 35 Part；5 parts of trehalose；5 parts of urea；3 parts of thickener；30 parts of water.

3. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that the Huang Smart extracting solution is made especially by following method：

S1：Clean fresh sealwort is taken, is crushed after slice, 20-80 mesh sieve is crossed, obtains sealwort powder；

S2：Above-mentioned sealwort powder is taken, according to solid-liquid ratio 1：10-20 adds water to mix；

S3：By mixed sealwort powder liquid, refluxing extraction 2 times, each reflux extracting time is that 1-2h extracts to get the sealwort Liquid.

4. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S1 Middle sealwort powder crosses 50-70 mesh sieve.

5. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S2 In, the mixed liquor ratio of sealwort powder and water is 1:15.

6. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 3, which is characterized in that step S3 In every time reflux extracting time be 1.5h.

7. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 1, which is characterized in that described Infusion is amino acid foaming agent, including one or more of ms-11 powder of amino acids foaming agent and No. 2 amino acid foaming agents.

8. a kind of facial cleanser containing sealwort with moisturizing repair function according to claim 7, which is characterized in that described The weight of ms-11 powder of amino acids foaming agent and No. 2 amino acid foaming agents is 2-5:1-2.

9. a kind of method preparing any facial cleansers with moisturizing repair function containing sealwort of claim 1-8, feature It is, includes the following steps：

A, raw material is classified：It weighs foaming agent, butanediol and pentanediol to be placed in A containers, then weighs polymer hyaluronic acid, urine Element, trehalose, thickener and water are placed in B containers；

B, the pre-heat treatment：By the raw material in above-mentioned A containers and B containers, it is preheated to 80-90 DEG C respectively；

C, mixing and emulsifying：By the raw material in the raw material and B containers in A containers after preheating, mix while stirring, and be maintained at 80- 90 DEG C of emulsified 10-20min；

D, sealwort extracting solution is added：Mixing speed is reduced, waits for that temperature is down to 60 DEG C, sealwort Aqueous extracts are added according to component proportion, Uniform stirring stops heating to after 48 DEG C at a slow speed, and after room temperature, bottling has moisturizing to get described containing sealwort The dairy products of washing one's face of repair function.

10. a kind of preparation method of facial cleanser with moisturizing repair function containing sealwort according to claim 9, feature It is, in step c, the raw material in the raw material and B containers in A containers after preheating mixes while stirring, and preferably at 85 DEG C Emulsify 10min.