CN108434202A - It is a kind of to treat five rattan electuary of rheumatoid arthritis - Google Patents
It is a kind of to treat five rattan electuary of rheumatoid arthritis Download PDFInfo
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- CN108434202A CN108434202A CN201711154137.2A CN201711154137A CN108434202A CN 108434202 A CN108434202 A CN 108434202A CN 201711154137 A CN201711154137 A CN 201711154137A CN 108434202 A CN108434202 A CN 108434202A
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- Prior art keywords
- caulis
- rattan
- rheumatoid arthritis
- electuary
- tripterygium wilfordii
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- Pending
Links
- 241000345998 Calamus manan Species 0.000 title claims abstract description 25
- 235000012950 rattan cane Nutrition 0.000 title claims abstract description 25
- 206010039073 rheumatoid arthritis Diseases 0.000 title claims abstract description 23
- 241000830536 Tripterygium wilfordii Species 0.000 claims abstract description 16
- 235000015398 thunder god vine Nutrition 0.000 claims abstract description 16
- 239000002245 particle Substances 0.000 claims abstract description 7
- 239000003814 drug Substances 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 6
- 208000006820 Arthralgia Diseases 0.000 abstract description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 201000010099 disease Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 241000287828 Gallus gallus Species 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000000845 cartilage Anatomy 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 239000002075 main ingredient Substances 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 206010065687 Bone loss Diseases 0.000 description 1
- INYYVPJSBIVGPH-VLXJIEOASA-N Cucoline Natural products C([C@H]1N(CC2)C)C3=CC=C(OC)C(O)=C3[C@@]32[C@@H]1C=C(OC)C(=O)C3 INYYVPJSBIVGPH-VLXJIEOASA-N 0.000 description 1
- 208000004044 Hypesthesia Diseases 0.000 description 1
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 241000501113 Sargentodoxa cuneata Species 0.000 description 1
- INYYVPJSBIVGPH-QHRIQVFBSA-N Sinomenine Chemical compound C([C@@H]1N(CC2)C)C3=CC=C(OC)C(O)=C3[C@@]32[C@@H]1C=C(OC)C(=O)C3 INYYVPJSBIVGPH-QHRIQVFBSA-N 0.000 description 1
- 241000545405 Tripterygium Species 0.000 description 1
- DFBIRQPKNDILPW-CIVMWXNOSA-N Triptolide Chemical compound O=C1OCC([C@@H]2C3)=C1CC[C@]2(C)[C@]12O[C@H]1[C@@H]1O[C@]1(C(C)C)[C@@H](O)[C@]21[C@H]3O1 DFBIRQPKNDILPW-CIVMWXNOSA-N 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007791 dehumidification Methods 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000001969 hypertrophic effect Effects 0.000 description 1
- 208000034783 hypoesthesia Diseases 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000001258 synovial membrane Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- YKUJZZHGTWVWHA-UHFFFAOYSA-N triptolide Natural products COC12CC3OC3(C(C)C)C(O)C14OC4CC5C6=C(CCC25C)C(=O)OC6 YKUJZZHGTWVWHA-UHFFFAOYSA-N 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Five rattan electuary of rheumatoid arthritis is treated the invention discloses a kind of, it includes tripterygium wilfordii, caulis sinomenii, caulis lonicerae, Caulis Spatholobi and caulis trachelospermi to make formula；The percentage for forming each component of five rattan electuaries is：Tripterygium wilfordii 14% 17%；Caulis sinomenii 15% 17%；Caulis lonicerae 19% 22%；Caulis Spatholobi 30% 32%；Caulis trachelospermi 14% 18%；The summation of the above component is 100%.Selected five kinds of the present invention commonly uses effective Chinese medicine (tripterygium wilfordii, caulis lonicerae, Caulis Spatholobi, caulis trachelospermi, caulis sinomenii), and particle is made after extracted, dry, concentration, forms five rattan electuaries, has effects that clearing heat and detoxicating, expelling wind, removing dampness and detumescence.Treat the damp-heat arthralgia resistance card of rheumatoid arthritis active stage.
Description
Technical field
The present invention relates to Chinese medicine application and preparation technical fields, specially a kind of to treat five rattan electuary of rheumatoid arthritis.
Background technology
Rheumatoid arthritis is the inflammatory reaction disease caused by a kind of immune system disorder.It is a kind of high disable
The big common disease of rate, harmfulness, frequently-occurring disease.It is main to invade whole body joint everywhere, in multiple, symmetry, chronic, Hypertrophic synovial membrane
It is scorching.Symmetry, chronic, progressive panarthritis are shown as, joint deformity is eventually led to and function is lost.Rheumatoid arthrosis at present
Scorching pathogenesis not yet illustrates, and clinically still lacks radical cure and prevents the effective measures of this disease.Treatment rheumatoid is closed both at home and abroad
The scorching purpose of section is to prevent destruction of joint, Saving cortilage function, mitigate arthralgia, improves minimal invasive treatment's matter to greatest extent
Amount.Western medical treatment is mainly relieved pain with non-steroidal anti-inflammatory drugs and inflammation.It is slow to make medication reduction or delay osteoclasia.Methotrexate (MTX)
It is common rheumatoid arthritis standard care medication.But research has shown that, can slow down rheumatoid arthritis destruction of bone into
Journey, but cartilage and bone loss cannot be prevent completely.Countries in the world are all to seek specific therapy and drug and effort.But at present
In the control rheumatoid arthritis state of an illness, prevent still to suffer from not having good plan in terms of destruction of joint.
In traditional Chinese medicine, rheumatoid arthritis generally falls into " numbness disease " scope.Chinese medicine has control symptom, improves
The unique advantage of quality of life compensates for the deficiency of western medical treatment to a certain extent.Treatment to rheumatoid arthritis, Chinese medicine
Have accumulated abundant experience.This disease Chinese medical discrimination active stage is that damp-heat arthralgia resistance is main feature, is treated with clearing heat and detoxicating, dampness removing
Dredging collateral is the rules for the treatment of.Paracmasis characterized by weakened body resistance companion's domination of pathogen, based on the kidney qi cold of insufficiency type, Yu Xue Bi resistance, is controlled with warming kidney and strengthening spleen, promoting blood circulation
Dredging collateral.
In the prior art, the rheumatic diseases such as rheumatoid arthritis by TCM are with a long history, and curative effect is more definite.But
Indefinite mechanism of action is develop the major reason for influencing Chinese medicine further genralrlization.
Invention content
Five rattan electuary of rheumatoid arthritis is treated the purpose of the present invention is to provide a kind of, to solve in above-mentioned background technology
The problem of proposition.
To achieve the above object, the present invention provides the following technical solutions：It is a kind of to treat five rattan electuary of rheumatoid arthritis,
It includes tripterygium wilfordii, caulis sinomenii, caulis lonicerae, Caulis Spatholobi and caulis trachelospermi to make formula；Form the percentage of each component of five rattan electuaries
For：
Tripterygium wilfordii 14%-17%；
Caulis sinomenii 15%-17%；
Caulis lonicerae 19%-22%；
Caulis Spatholobi 30%-32%；
Caulis trachelospermi 14%-18%；
The summation of the above component is 100%.
It is a kind of to treat five rattan electuary of rheumatoid arthritis, particle is made after extracted, dry, concentration, finally obtains particle
Five rattan electuaries of shape.
Compared with prior art, the beneficial effects of the invention are as follows：The common effective Chinese medicine of selected five kinds of the present invention (tripterygium wilfordii,
Caulis lonicerae, Caulis Spatholobi, caulis trachelospermi, caulis sinomenii), particle is made after extracted, dry, concentration, forms five rattan electuaries, there is heat-clearing
The effect of removing toxic substances, expelling wind, removing dampness and detumescence.Treat the damp-heat arthralgia resistance card of rheumatoid arthritis active stage.
Specific implementation mode
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
The every other embodiment that technical staff is obtained without making creative work belongs to the model that the present invention protects
It encloses.
It is provided by the invention it is a kind of treat five rattan electuary of rheumatoid arthritis, make formula include tripterygium wilfordii, caulis sinomenii,
Caulis lonicerae, Caulis Spatholobi and caulis trachelospermi；The percentage for forming each component of five rattan electuaries is：
Tripterygium wilfordii 14%-17%；
Caulis sinomenii 15%-17%；
Caulis lonicerae 19%-22%；
Caulis Spatholobi 30%-32%；
Caulis trachelospermi 14%-18%；
The summation of the above component is 100%.
Particle is made after extracted, dry, concentration, finally obtains granular five rattans electuary.
Embodiment 1：
The five rattan electuary for the treatment of rheumatoid arthritis for preparing 100g, using tripterygium wilfordii 16g；Caulis sinomenii 15g；Caulis lonicerae 19g；
Caulis Spatholobi 32g；Caulis trachelospermi 18g；Other are water.
Embodiment 2：
Prepare the five rattan electuary for the treatment of rheumatoid arthritis of 100g, tripterygium wilfordii 15g；Caulis sinomenii 15g；Caulis lonicerae 20g；Chicken blood
Rattan 30g；Caulis trachelospermi 15g；Other are water.
Embodiment 3：
Prepare the five rattan electuary for the treatment of rheumatoid arthritis of 100g, tripterygium wilfordii 17g；Caulis sinomenii 16g；Caulis lonicerae 21g；Chicken blood
Rattan 31g；Caulis trachelospermi 16g；Other are water.
Selected five kinds common effective Chinese medicines (tripterygium wilfordii, caulis lonicerae, Caulis Spatholobi, caulis trachelospermi, caulis sinomenii), extracted, dry,
Particle is made after concentration, forms five rattan electuaries, has effects that clearing heat and detoxicating, expelling wind, removing dampness and detumescence.Treat rheumatoid arthritis
The damp-heat arthralgia resistance card of active stage.
Tripterygium wilfordii, caulis sinomenii are main ingredient, have effects that wind-dispelling removing toxic substances, dehumidification swelling.
The main ingredient ingredient of tripterygium wilfordii is tripterygium glycosides, triptolide, modern research shows that with immunosupress, resisting
The effects that scorching, inhibition blood vessel hyperplasia, protection cartilage and gene regulation.
Cucoline in caulis sinomenii has the pharmacological actions such as anti-inflammatory, immunosupress, analgesia.
Caulis lonicerae, sargentodoxa cuneata have the function of clearing heat and detoxicating, and caulis trachelospermi dispelling wind and removing obstruction in the meridians, cool blood detumescence, all medicines share are played altogether
The benefits of clearing heat and detoxicating, dispelling wind and eliminating dampness dredging collateral.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Profit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent requirements of the claims
Variation is included within the present invention.
Claims (2)
- Treat five rattan electuary of rheumatoid arthritis 1. a kind of, make formula include tripterygium wilfordii, caulis sinomenii, caulis lonicerae, Caulis Spatholobi and Caulis trachelospermi；It is characterized in that：The percentage for forming each component of five rattan electuaries is：Tripterygium wilfordii 14%-17%；Caulis sinomenii 15%-17%；Caulis lonicerae 19%-22%；Caulis Spatholobi 30%-32%；Caulis trachelospermi 14%-18%；The summation of the above component is 100%.
- 2. a kind for the treatment of five rattan electuary of rheumatoid arthritis, it is characterised in that：Particle is made after extracted, dry, concentration, finally Obtain granular five rattans electuary.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154137.2A CN108434202A (en) | 2017-11-20 | 2017-11-20 | It is a kind of to treat five rattan electuary of rheumatoid arthritis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711154137.2A CN108434202A (en) | 2017-11-20 | 2017-11-20 | It is a kind of to treat five rattan electuary of rheumatoid arthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108434202A true CN108434202A (en) | 2018-08-24 |
Family
ID=63190599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711154137.2A Pending CN108434202A (en) | 2017-11-20 | 2017-11-20 | It is a kind of to treat five rattan electuary of rheumatoid arthritis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108434202A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196251A (en) * | 1997-04-11 | 1998-10-21 | 姬元璋 | Medicinal liquor for treating rheumatoid disease and preparation technology thereof |
| CN1342462A (en) * | 2000-09-08 | 2002-04-03 | 何兴峰 | Composite medicine for treating rheumatoid arthritis |
| KR20100091586A (en) * | 2009-02-11 | 2010-08-19 | 경희대학교 산학협력단 | Composition containing extracts of vigna sinensis king inhibiting inflammation and prevent arthritis |
-
2017
- 2017-11-20 CN CN201711154137.2A patent/CN108434202A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1196251A (en) * | 1997-04-11 | 1998-10-21 | 姬元璋 | Medicinal liquor for treating rheumatoid disease and preparation technology thereof |
| CN1342462A (en) * | 2000-09-08 | 2002-04-03 | 何兴峰 | Composite medicine for treating rheumatoid arthritis |
| KR20100091586A (en) * | 2009-02-11 | 2010-08-19 | 경희대학교 산학협력단 | Composition containing extracts of vigna sinensis king inhibiting inflammation and prevent arthritis |
Non-Patent Citations (1)
| Title |
|---|
| 李育林等: "五藤冲剂联合甲氨蝶呤治疗类风湿关节炎的临床研究", 《中国现代应用药学》 * |
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Application publication date: 20180824 |
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