CN108392433A - A kind of hair dye of composite dosage form - Google Patents
A kind of hair dye of composite dosage form Download PDFInfo
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- CN108392433A CN108392433A CN201810321494.1A CN201810321494A CN108392433A CN 108392433 A CN108392433 A CN 108392433A CN 201810321494 A CN201810321494 A CN 201810321494A CN 108392433 A CN108392433 A CN 108392433A
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- hair dye
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- hair
- dye according
- plant extracts
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- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 claims abstract 10
- 239000000118 hair dye Substances 0.000 claims abstract 10
- 244000018716 Impatiens biflora Species 0.000 claims abstract 6
- 235000015912 Impatiens biflora Nutrition 0.000 claims abstract 6
- 235000005155 Tanacetum balsamita Nutrition 0.000 claims abstract 6
- 239000000419 plant extract Substances 0.000 claims abstract 6
- 239000002243 precursor Substances 0.000 claims abstract 5
- WZUVPPKBWHMQCE-UHFFFAOYSA-N Haematoxylin Chemical compound C12=CC(O)=C(O)C=C2CC2(O)C1C1=CC=C(O)C(O)=C1OC2 WZUVPPKBWHMQCE-UHFFFAOYSA-N 0.000 claims abstract 4
- 239000000284 extract Substances 0.000 claims abstract 4
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims abstract 2
- 244000080767 Areca catechu Species 0.000 claims abstract 2
- 235000006226 Areca catechu Nutrition 0.000 claims abstract 2
- 241000219495 Betulaceae Species 0.000 claims abstract 2
- 240000008632 Cota tinctoria Species 0.000 claims abstract 2
- 244000068988 Glycine max Species 0.000 claims abstract 2
- 235000010469 Glycine max Nutrition 0.000 claims abstract 2
- 241000218231 Moraceae Species 0.000 claims abstract 2
- 235000008708 Morus alba Nutrition 0.000 claims abstract 2
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract 2
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract 2
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract 2
- 244000170916 Paeonia officinalis Species 0.000 claims abstract 2
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract 2
- 240000001341 Reynoutria japonica Species 0.000 claims abstract 2
- 235000018167 Reynoutria japonica Nutrition 0.000 claims abstract 2
- 240000003152 Rhus chinensis Species 0.000 claims abstract 2
- 235000014220 Rhus chinensis Nutrition 0.000 claims abstract 2
- 244000143590 Salvia chinensis Species 0.000 claims abstract 2
- 235000007154 Salvia chinensis Nutrition 0.000 claims abstract 2
- 235000005794 Salvia japonica Nutrition 0.000 claims abstract 2
- 240000000513 Santalum album Species 0.000 claims abstract 2
- 235000008632 Santalum album Nutrition 0.000 claims abstract 2
- 244000269722 Thea sinensis Species 0.000 claims abstract 2
- 235000006468 Thea sinensis Nutrition 0.000 claims abstract 2
- 241000052209 Triplasis Species 0.000 claims abstract 2
- 239000002253 acid Substances 0.000 claims abstract 2
- 235000020279 black tea Nutrition 0.000 claims abstract 2
- 239000002131 composite material Substances 0.000 claims abstract 2
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 239000002552 dosage form Substances 0.000 claims abstract 2
- 229910052736 halogen Inorganic materials 0.000 claims abstract 2
- 125000005843 halogen group Chemical group 0.000 claims abstract 2
- 230000007935 neutral effect Effects 0.000 claims abstract 2
- 150000003839 salts Chemical class 0.000 claims abstract 2
- 210000000582 semen Anatomy 0.000 claims abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 4
- 238000013329 compounding Methods 0.000 claims 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 3
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 claims 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical compound COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 claims 2
- 241000196324 Embryophyta Species 0.000 claims 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims 2
- 239000003963 antioxidant agent Substances 0.000 claims 2
- 230000003078 antioxidant effect Effects 0.000 claims 2
- 235000006708 antioxidants Nutrition 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- -1 polyoxyethylene Polymers 0.000 claims 2
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- GDSOZVZXVXTJMI-SNAWJCMRSA-N (e)-1-methylbut-1-ene-1,2,4-tricarboxylic acid Chemical compound OC(=O)C(/C)=C(C(O)=O)\CCC(O)=O GDSOZVZXVXTJMI-SNAWJCMRSA-N 0.000 claims 1
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims 1
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 claims 1
- AXPZIVKEZRHGAS-UHFFFAOYSA-N 3-benzyl-5-[(2-nitrophenoxy)methyl]oxolan-2-one Chemical compound [O-][N+](=O)C1=CC=CC=C1OCC1OC(=O)C(CC=2C=CC=CC=2)C1 AXPZIVKEZRHGAS-UHFFFAOYSA-N 0.000 claims 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 claims 1
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- 229920001661 Chitosan Polymers 0.000 claims 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 1
- 235000021314 Palmitic acid Nutrition 0.000 claims 1
- QOSMNYMQXIVWKY-UHFFFAOYSA-N Propyl levulinate Chemical compound CCCOC(=O)CCC(C)=O QOSMNYMQXIVWKY-UHFFFAOYSA-N 0.000 claims 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 1
- 235000019484 Rapeseed oil Nutrition 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000001273 butane Substances 0.000 claims 1
- 235000019438 castor oil Nutrition 0.000 claims 1
- 239000004359 castor oil Substances 0.000 claims 1
- 229940082500 cetostearyl alcohol Drugs 0.000 claims 1
- 239000008367 deionised water Substances 0.000 claims 1
- 229910021641 deionized water Inorganic materials 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
- 239000000706 filtrate Substances 0.000 claims 1
- 239000003292 glue Substances 0.000 claims 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims 1
- 239000008169 grapeseed oil Substances 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims 1
- CKQVRZJOMJRTOY-UHFFFAOYSA-N octadecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCCCC(O)=O CKQVRZJOMJRTOY-UHFFFAOYSA-N 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000001294 propane Substances 0.000 claims 1
- 235000010265 sodium sulphite Nutrition 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 229920001285 xanthan gum Polymers 0.000 claims 1
- 240000007829 Haematoxylum campechianum Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/10—Preparations for permanently dyeing the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
- A61K2800/432—Direct dyes
- A61K2800/4324—Direct dyes in preparations for permanently dyeing the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of hair dyes of composite dosage form, including melanin precursor and natural plant extracts, wherein the melanin precursor is halogen acid salt shown in compound or formula II shown in formula I；
Description
Technical field
The present invention relates to a kind of hair dye more particularly to a kind of hair dyes of composite dosage form, belong to special cosmetics technology
Field.
Background technology
Hair dye is the specific use for referring to change hair color, hair is dyed to the different depth different colours of color
Cosmetics.The property of raw material used in hair dye plays the role of the safety of hair dye and coloring conclusive.It opens
Hair safety and efficient hair dye are the demand in consumer and market, the nineties in 20th century, possessed by human body itself
Melanin and its Forming Mechanism of inherence are set about, and develop commercially valuable new raw material and safe hair dye becomes as one kind
Gesture.
Natural black pigment (melanin) is a kind of endogenic substance being widely present in organism, in animal body
Black disorderly and black human hair is all by the biochemical catalytic action of the copper tyrosinase in melanocyte, by the ammonia of phenolic hydroxy group
Base acid is that raw material carries out being converted into melanin precursor (or presoma) small molecule, and then is polymerized to melanin polymer so that people
Black is presented in hair, the colour of skin of people and the animal body colour of skin.
According to the biomechanism that melanin is formed, the companies such as Japanese Kao and L'Oreal, France are in nineteen nineties
It begins one's study and utilizes the new raw material of melanin precursor (or presoma) small molecule exploitation hair dye and production, the corresponding hair dyeing of listing
Agent.European patent EP 0530229B1 takes the lead in reporting 5,6- dihydroxy indoles quinoline (or 5,6- dihydroxy indoline) and its spread out
Biology is used as dyeing raw material；Chinese patent CN1196463C and CN1216591C report 5,6- dihydroxy indole quinolines within 2005
(or 5,6- dihydroxy indoline) and its derivative, the multicomponents such as 5,6- dihydroxy indoles and its derivative are former as dyeing
Material.Wherein, the chemical structural formula of 5,6- dihydroxy indoles quinoline derivant and 5,6- dihydroxy indole derivatives is as follows：
Hair dye prepared by this dyeing raw material this have the advantage that, natural hair dye melanocyte is applied on hair, is made
It uses the oxygen in air to be dyed as unique oxidant, generates similar natural color.The disadvantage is that each pigment raw material pair
The coloured color development of original and hair quality of the people answered is single, that is, each pigment raw material must find the color development to match and could reach
To relatively satisfactory effect；For example, when using the hair dye of the dihydroxy indole quinoline Han 5,6-, needing to be used for multiple times can just make
People with grey hair has natural color development again.Hair can use indoline in the natural light golden yellow people to brown
(or indoline) is used as unique dyestuff former；But in hair in natural red, especially dark, grey to black
People is in use, being used together and could be enabled often only by with other dye components (especially oxidation dye precursors)
The effect of people's satisfaction.That is, the universality of these dyeing raw materials is too poor.In addition, colorability when dyeing is weaker, need
Repeated multiple times dyeing, can be only achieved expected effect.
Many natural plants in China's Chinese traditional herbs, for example Chinese gall, the fleece-flower root, hematoxylin, Semen sesami nigrum, black soya bean, refer to
First flower, yellow chamomile etc., are all derived from the Nature, are used to prepare that coloring agent is very safe, and have nourishing to hair and human body
Effect；But often to have that effect is poor, coloring is low, the color and luster duration is short etc. scarce for the hair dye for being applied alone these plants to develop
Point.
Invention content
The present invention is carried for deficiency existing for the hair dye for relying on existing melanin precursor and Chinese herbal medicine extract exploitation
For the hair dye of composite dosage form.
The technical solution that the present invention solves above-mentioned technical problem is as follows：
A kind of hair dye of composite dosage form, including melanin precursor and natural plant extracts, wherein institute
It is halogen acid salt shown in compound or formula II shown in formula I to state melanin precursor；
Any one of the natural plant extracts in following situations；
1) any one in mulberries, Semen sesami nigrum, black soya bean, hematoxylin, the fleece-flower root, Chinese herbaceous peony, lotus rhizome and Chinese gall or two kinds
Or more extract；
2) garden balsam, neutral garden balsam, deep garden balsam, yellow chamomile, black tea, catechu, Salvia japonica, sandalwood, alder tree
The extract of any one or two kinds or more in skin, logwood, sand-grass and purple timothy root.
It, can be by white, canescence, faint yellow, golden yellow, red etc. when natural plant extracts are 1) kind situation
The human hair of a variety of colors dyes nature black to corvinus；
It, can be by the cutin protein fiber of a variety of colors especially human hair when natural plant extracts are 2) kind situation
Dye the different color result such as salmon pink, red, rufous, yellowish-brown, grey and black, as a result color and luster is depended on
A ingredients and the opposite dosage of B component.
Further, including following component：0.5~10wt% of melanin precursor, 2.0~20wt% of natural plant extracts,
2~12wt% of lipid, 2~5wt% of surfactant, 0.1~0.5wt% of antioxidant, 1~10wt% of alkaline agent, thickener
0.1~1.0wt%, 1~10wt% of organic solvent, surplus are water.
Further, the preparation method of the natural plant extracts is as follows：It mixes, be added and plant after natural plants are crushed
The identical deionized water of object total weight is heated to soak extraction 5 hours at 40~50 DEG C；Then, filter and remove residue obtains clear
Filtrate to get.
Further, the lipid refers to 1,3-BDO, glycerine, grape seed oil, rapeseed oil, castor oil, the fat of C12~18
The fatty alcohol of fat alcohol, C16~18, cetylstearyl alcohol, isopropyl palmitate, isopropyl myristate, synthesis saualane, list
The compounding of any one or two kinds or more in tristerin, the fatty alcohols of preferably C12~18, the fatty alcohols of C16~18, ten
Six alkyl octadecanols.
Further, the alkaline agent refers to any one in monoethanolamine, histidine, arginine or two kinds or more
The pH of compounding, preferably arginine, regulation system is 8.5~9.5.
Further, the antioxidant refers to any one in ascorbic acid, arabo-ascorbic acid, sodium sulfite or two kinds
Or more compounding, preferred ascorbic acid.
Further, the surfactant refers to that ceteareth series, stearine, polyoxyethylene -2 are hard
The compounding of any one or two kinds or more in the stearic alcohol ether of lipidol ether, polyoxyethylene -21, preferably glycerine stearate.
Further, the thickener refers to hydroxyethyl cellulose, xanthans or chitosan, preferably hydroxyethyl cellulose.
Further, the organic solvent refer to 75% or more ethyl alcohol of concentration, ethylene glycol, glycerine, ethane, propane, butane,
Dimethyl ether, propylene oxide when especially cream rinse is as dosage form, preferably select hydraulic pressure ethane when preparing hair dye finished product
Or hydraulic pressure propane etc..
The beneficial effects of the invention are as follows：
1) composite dosage form hair dye of the invention has extraordinary polymerization activity, during dyeing, has coloring
Soon, lasting advantage is coloured, it is only necessary to hair dye is applied on hair, kept for 5-10 minutes time, can be shown after cleaning
Show natural color and luster effect, such as natural black, corvinus etc.；Primary hair dyeing can keep 6 months to 12 months it is colour-fast；
2) composite dosage form hair dye no stimulation safe to the human body of the invention, have no toxic side effect.Simultaneous oxidation agent
Using the oxygen in air as unique oxidant, need not be added with strong oxidizing property, strong and stimulating, easily decomposes peroxide
Change other oxidants such as hydrogen.
3) composite dosage form hair dye stability of the invention is high, is easy to store.At closing (must not ingress of air or oxygen)
Under state, stablize in aqueous solution；The hair dye of preparation can be placed for a long time, placed for 2 years, be again started up, do not influence to contaminate
Send out effect.
4) composite dosage form hair dye of the invention can also nourish hair while dyeing, compensate for single in the prior art
Solely use existing 5,6- dihydroxy indoles quinoline derivant and 5, the melanin precursor of 6- dihydroxy indole derivatives and natural plant
The shortcomings that object extract does hair dye, the advantages of having gathered the two, have industrial prospect and huge commercial value.
Specific implementation mode
Principles and features of the present invention are described below in conjunction with example, the given examples are served only to explain the present invention, and
It is non-to be used to limit the scope of the present invention.
Natural botanical extraction liquid used in the embodiment of the present invention is prepared via a method which to obtain：
It is mixed after fresh plant is crushed, the deionized water with plant total weight identical weight is added, is heated to 40~50
It is impregnated 5 hours at DEG C；Then, filter and remove residue obtains clear filtrate, the as plant extraction liquid used in hair dye.
Embodiment 1：
A kind of hair dye of composite dosage form, including following component：
Melanin precursor 4wt% shown in formula I；Mulberries, Semen sesami nigrum, black soya bean three are according to mass ratio 1：2：1 is mixed
Extracting solution 10wt%；The fatty alcohols of the lipid C12~18 fatty alcohol 6wt% of 2wt%, C16~18, cetylstearyl alcohol
2wt%；Surfactant stearin 2wt%；Antioxidants ascorbic acid 0.3wt%；Alkaline agent arginine (adjusts pH
For 9.0) 3wt%；95% ethyl alcohol 2wt% of organic solvent；Thickener hydroxyethyl cellulose 0.2wt%；Deionized water surplus.
The effect of 1 hair dye of embodiment is that cutin protein fiber, especially human hair are dyed nature black.
Embodiment 2：
A kind of hair dye of composite dosage form, including following component：
Hydrobromate is as melanin precursor 10wt% shown in formula II；Mulberries, Semen sesami nigrum, black soya bean and the fleece-flower root are pressed
According to mass ratio 1：1：1：1 mixed extracting solution 20wt%；Lipid 1,3-BDO 2wt%, grape seed oil 4wt%；It lives on surface
Property agent polyoxyethylene -2 stearic alcohol ether 3wt%；Oxidation preventive isoascorbic acid 0.5wt%；(adjust pH is alkaline agent histidine
9.0) 6wt%；Organic solvent ethylene glycol 1wt%；Thickener xanthans 0.1wt%；Deionized water surplus.
The effect of 2 hair dye of embodiment is that cutin protein fiber, especially human hair are dyed black to corvinus.
Embodiment 3：
A kind of hair dye of composite dosage form, including following component：
Hydrochloride is as melanin precursor 6wt% shown in formula II；Chinese herbaceous peony, lotus rhizome, Chinese gall, hematoxylin and the fleece-flower root are pressed
According to mass ratio 1：1：1：1：1 mixed extracting solution 2wt%；Lipid glycerine 2wt%, isopropyl palmitate 4wt%, synthesis spiny dogfish
Alkane 6wt%；The stearic alcohol ether 3wt% of surfactant polyoxyethylene -2, stearin 2wt%；Antioxidant sodium sulfite
0.2wt%；Alkaline agent monoethanolamine (it is 9.0 to adjust pH) 10wt%；Organic solvent hydraulic pressure propane 5wt%；Thickener xanthans
0.3wt%；Deionized water surplus.
The effect of 3 hair dye of embodiment is that cutin protein fiber, especially human hair are dyed black to corvinus.
Embodiment 4：
A kind of hair dye of composite dosage form, including following component：
Melanin precursor 2wt% shown in formula I；Garden balsam, neutral garden balsam, deep garden balsam, catechu, Salvia japonica are according to matter
Measure ratio 1：1：1：1：1 mixed extracting solution 8wt%；Lipid isopropyl myristate 2wt%；Surfactant polyoxyethylene-
21 stearic alcohol ether 2wt%；Antioxidants ascorbic acid sodium 0.3wt%；Alkaline agent arginine 1wt%；95% ethyl alcohol of organic solvent
10wt%；Thickener hydroxyethyl cellulose 1.0wt%；Surplus is water.
The effect of 4 hair dye of embodiment is that cutin protein fiber, especially human hair are dyed brown to rufous.
Embodiment 5：
A kind of hair dye of composite dosage form, including following component：
Hydrobromate is as melanin precursor 0.5wt% shown in formula II；Neutral garden balsam, yellow chamomile, sandalwood, sand
Grass and black tea three are according to mass ratio 1：2：1：1：1 mixed extracting solution 12wt%；Lipid cetylstearyl alcohol
2wt%, castor oil 2wt%；Surfactant ceteareth 3wt%；Oxidation preventive isoascorbic acid sodium 0.1wt%；
Alkaline agent histidine 3wt%；Organic solvent dimethyl ether 3wt%；Thickener xanthans 0.8wt%；Surplus is water.
The effect of 5 hair dye of embodiment is to dye cutin protein fiber, especially human hair golden yellow to deep golden yellow.
Embodiment 6：
A kind of hair dye of composite dosage form, including following component：
Hydrobromate is as melanin precursor 0.5wt% shown in formula II；Neutral garden balsam, yellow chamomile, alder bark,
Logwood and purple timothy root three are according to mass ratio 1：2：1：1：1 mixed extracting solution 12wt%；Lipid cetyl 18
Alkanol 2wt%, castor oil 2wt%；Surfactant ceteareth 3wt%；Oxidation preventive isoascorbic acid sodium
0.1wt%；Alkaline agent histidine 3wt%；Organic solvent dimethyl ether 3wt%；Thickener xanthans 0.8wt%；Surplus is water.
The effect of 6 hair dye of embodiment is to dye cutin protein fiber, especially human hair golden yellow to deep golden yellow.
The hair colouring methods and result of the formula hair dye of Examples 1 to 3 are as follows：
Using the hair dye of Examples 1 to 3 formula respectively to white, canescence, faint yellow, golden yellow and five kinds red etc.
The human hair of color is dyed；As a result as follows：
1) rubbing after five minutes, the foam for removing hair surface is eluted with clear water；As a result the hair of all colours is all dyed to
Natural black.
2) rubbing after ten minutes, the foam for removing hair surface is eluted with clear water；As a result, the hair of all colours is all contaminated
At corvinus.
The hair colouring methods and result of the formula hair dye of embodiment 4~6 are as follows：
The hair dye being formulated using embodiment 4~6 is respectively to five kinds of face such as white, canescence, faint yellow, grey and black
The human hair of color is dyed；Rubbing after ten minutes, the foam for removing hair surface is eluted with clear water；As a result, the head of all colours
Hair has all been dyed to brown to rufous (embodiment 4) and golden yellow to deep golden yellow (embodiment 5,6) respectively.
In dyeing course, no peculiar smell the skin being in direct contact such as does not stimulate and uncomfortable feels.Illustrate these hair dyeings
Agent has that dye the cutin protein fiber (especially human hair) of various original different colours be the general of nature black or other colors
Adaptive, safety and coloring are quickly.
Hair sample after we dye above-described embodiment 1~5 places 6 under the different temperatures of 0 DEG C to 50 DEG C of temperature
A month and 12 months, the variation of color is not observed, for example fades etc.；Hair after dyeing elutes repeatedly through clear water, at 3
Month and compareed respectively within 6 months, color does not have significant change.Illustrate that the dyeing of these hair dyes is lasting, effect is good.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention.
Claims (9)
1. a kind of hair dye of composite dosage form, which is characterized in that including melanin precursor and natural plant extracts, wherein institute
It is halogen acid salt shown in compound or formula II shown in formula I to state melanin precursor；
Any one of the natural plant extracts in following situations；
1) any one in mulberries, Semen sesami nigrum, black soya bean, hematoxylin, the fleece-flower root, Chinese herbaceous peony, lotus rhizome and Chinese gall or two kinds and with
On extract；
2) garden balsam, neutral garden balsam, deep garden balsam, yellow chamomile, black tea, catechu, Salvia japonica, sandalwood, alder bark, ocean
The extract of any one or two kinds or more in bush, sand-grass and purple timothy root.
2. hair dye according to claim 1, which is characterized in that include following component：Melanin precursor 0.5~
10wt%, 2.0~20wt% of natural plant extracts, 2~12wt% of lipid, 2~5wt% of surfactant, antioxidant 0.1
~0.5wt%, 1~10wt% of alkaline agent, 0.1~1.0wt% of thickener, 1~10wt% of organic solvent, surplus are water.
3. hair dye according to claim 2, which is characterized in that the preparation method of the natural plant extracts is as follows：
It is mixed after natural plants are crushed, deionized water identical with plant total weight is added, is heated to soak extraction 5 at 40~50 DEG C
Hour；Then, filter and remove residue, obtain clear filtrate to get.
4. hair dye according to claim 2 or 3, which is characterized in that the lipid refers to 1,3-BDO, glycerine, Portugal
Grape seed oil, rapeseed oil, castor oil, the fatty alcohols of C12~18, the fatty alcohols of C16~18, cetylstearyl alcohol, palmitic acid are different
The compounding of propyl ester, isopropyl myristate, synthesis saualane, any one or two kinds or more in glycerin monostearate.
5. hair dye according to claim 2 or 3, which is characterized in that the alkaline agent refer to monoethanolamine, histidine,
The compounding of any one or two kinds or more in arginine.
6. hair dye according to claim 2 or 3, which is characterized in that the antioxidant refers to ascorbic acid, different anti-bad
The compounding of any one or two kinds or more in hematic acid, sodium sulfite.
7. hair dye according to claim 2 or 3, which is characterized in that the surfactant refers to that cetostearyl alcohol is poly-
Any one in the stearic alcohol ether of ether series, stearine, polyoxyethylene -2, the stearic alcohol ether of polyoxyethylene -21 or two kinds
Or more compounding.
8. hair dye according to claim 2 or 3, which is characterized in that the thickener refers to hydroxyethyl cellulose, xanthan
Glue or chitosan.
9. hair dye according to claim 2 or 3, which is characterized in that the organic solvent refers to 75% or more second of concentration
Alcohol, ethylene glycol, glycerine, ethane, propane, butane, dimethyl ether, propylene oxide.
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| CN109674680A (en) * | 2019-01-30 | 2019-04-26 | 苏州妮优雅化妆品有限公司 | A kind of hair coloring preparation composition |
| CN109758389A (en) * | 2018-10-29 | 2019-05-17 | 武威福民汇科技开发有限公司 | A kind of processing method of green peel of walnut day hair dye |
| CN111759763A (en) * | 2020-07-14 | 2020-10-13 | 佛山市喜妆化妆品有限公司 | Plant hair dye containing black sesame melanin |
| CN115006320A (en) * | 2022-05-11 | 2022-09-06 | 长沙千草颂电子商务有限公司 | Aniline-free and phenol-free natural plant hair conditioner for black hair dyeing and preparation method |
| WO2025020591A1 (en) * | 2023-07-25 | 2025-01-30 | 北京立仁堂医药科技开发有限公司 | Pigment composition for dyeing hair, blackening hair and nourishing hair, and use thereof |
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| CN115006320A (en) * | 2022-05-11 | 2022-09-06 | 长沙千草颂电子商务有限公司 | Aniline-free and phenol-free natural plant hair conditioner for black hair dyeing and preparation method |
| WO2025020591A1 (en) * | 2023-07-25 | 2025-01-30 | 北京立仁堂医药科技开发有限公司 | Pigment composition for dyeing hair, blackening hair and nourishing hair, and use thereof |
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| CN108392433B (en) | 2020-09-01 |
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