CN108379678B - A hemodialysis machine dialysis effect detection system and its control method - Google Patents
A hemodialysis machine dialysis effect detection system and its control method Download PDFInfo
- Publication number
- CN108379678B CN108379678B CN201810095341.XA CN201810095341A CN108379678B CN 108379678 B CN108379678 B CN 108379678B CN 201810095341 A CN201810095341 A CN 201810095341A CN 108379678 B CN108379678 B CN 108379678B
- Authority
- CN
- China
- Prior art keywords
- liquid
- storage device
- switch
- liquid storage
- control device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/70—General characteristics of the apparatus with testing or calibration facilities
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
本发明公开了一种血透机透析效果检测系统及其控制方法，该系统包括配液装置、储液装置、温度控制装置、压力控制装置、入口泵、过滤器、单向阀、出口泵、比例阀、开关和管路；配液装置通过管路、入口泵、过滤器、单向阀和储液装置进液口相连，储液装置出液口通过过滤器、出口泵、比例阀和两个开关分别和配液装置回流口及血透机透析器入口相连，血透机透析器出口处通过管路、单向阀和储液装置进液口相连，两个开关之间安装有温度控制装置和压力控制装置。通过调节压力控制装置和温度控制装置模拟人体的血压及血液温度，使透析过程更真实，从而更好的检测透析效果，一定程度上减少了患者进行血液透析的安全隐患。
The invention discloses a dialysis effect detection system of a hemodialysis machine and a control method thereof. The system comprises a liquid dispensing device, a liquid storage device, a temperature control device, a pressure control device, an inlet pump, a filter, a one-way valve, an outlet pump, Proportional valve, switch and pipeline; the liquid dispensing device is connected with the liquid storage device inlet through pipeline, inlet pump, filter, one-way valve, and the liquid storage device outlet is connected with the filter, outlet pump, proportional valve and two Two switches are respectively connected with the return port of the liquid dispensing device and the inlet of the dialyzer of the hemodialysis machine. The outlet of the dialyzer of the hemodialysis machine is connected with the liquid inlet port of the liquid storage device through a pipeline, a one-way valve, and a temperature control device is installed between the two switches. device and pressure control device. By adjusting the pressure control device and the temperature control device to simulate the blood pressure and blood temperature of the human body, the dialysis process is more realistic, so that the dialysis effect can be better detected, and the safety hazard of hemodialysis patients is reduced to a certain extent.
Description
所属领域Field of study
本发明涉及一种血透机透析效果检测系统及其控制方法。The invention relates to a dialysis effect detection system of a hemodialysis machine and a control method thereof.
背景技术Background technique
新研制出来的血透机都需要测试压力、超滤和电导率等多项功能，对于透析效果一般是通过电导率的变化来检测透析后透析液中含有的导电离子含量的变化，这种检测方法不能确定血液中的尿素、肌酐、血钾等是否被有效透析出来，也不能确定透析出不同的毒素所需要的时间；这样在临床运用时，就很难把握不同疾病患者、不同程度的病症所需要的有效的透析时间，这样接受透析治疗的病人就会承担一定的风险。The newly developed hemodialysis machine needs to test multiple functions such as pressure, ultrafiltration and conductivity. For the dialysis effect, the change in the content of conductive ions contained in the dialysate after dialysis is generally detected by the change in conductivity. The method cannot determine whether the urea, creatinine, serum potassium, etc. in the blood have been effectively dialyzed out, nor can it determine the time required for dialysis of different toxins; in this way, it is difficult to grasp patients with different diseases and symptoms of different degrees in clinical application. The required effective dialysis time, so that the patient receiving dialysis treatment will bear a certain risk.
发明内容SUMMARY OF THE INVENTION
发明目的：本发明提供一种可模拟出人体血压和温度的血透机透析效果检测系统，用于检测血透机的透析效果；同时提供了该系统的控制方法，可预估出不同疾病患者所需透析的时间。Purpose of the invention: The present invention provides a hemodialysis machine dialysis effect detection system that can simulate the blood pressure and temperature of the human body, and is used to detect the dialysis effect of the hemodialysis machine; at the same time, it provides a control method of the system, which can predict patients with different diseases Time required for dialysis.
技术方案：本发明所述的一种血透机透析效果检测系统，包括配液装置、储液装置、温度控制装置、压力控制装置、入口泵、过滤器、单向阀、出口泵、比例阀、开关和管路；配液装置通过管路、入口泵、过滤器、单向阀和储液装置进液口相连，储液装置出液口通过过滤器、出口泵、比例阀和两个开关分别和配液装置回流口及血透机透析器入口相连，血透机透析器出口处通过管路、单向阀和储液装置进液口相连，配液装置和储液装置形成环路，储液装置和血透机透析器形成环路；两个开关之间安装有温度控制装置和压力控制装置。Technical scheme: The hemodialysis effect detection system of the present invention includes a liquid dispensing device, a liquid storage device, a temperature control device, a pressure control device, an inlet pump, a filter, a one-way valve, an outlet pump, and a proportional valve. , switch and pipeline; the liquid dispensing device is connected with the liquid storage device inlet through pipeline, inlet pump, filter, one-way valve, and the liquid storage device liquid outlet is connected through the filter, outlet pump, proportional valve and two switches They are respectively connected with the return port of the liquid dispensing device and the inlet of the dialyzer of the hemodialysis machine. The outlet of the dialyzer of the hemodialysis machine is connected with the liquid inlet of the liquid storage device through a pipeline, a one-way valve, and the liquid dispensing device and the liquid storage device form a loop. The liquid storage device and the dialyzer of the hemodialysis machine form a loop; a temperature control device and a pressure control device are installed between the two switches.
所述温度控制装置包括温度传感器和安装于配液装置的加热棒。The temperature control device includes a temperature sensor and a heating rod installed on the liquid dispensing device.
所述压力控制装置包括泵、比例阀和压力传感器比例阀与泵并联。The pressure control device includes a pump, a proportional valve and a pressure sensor. The proportional valve is connected in parallel with the pump.
如上述所述的血透机透析效果检测系统的控制方法，包括以下步骤：The control method of the hemodialysis machine dialysis effect detection system as described above, comprises the following steps:
(1)根据不同疾病的血液特征，配置不同毒素含量的药液，并倒入配液装置中；(1) According to the blood characteristics of different diseases, prepare liquids with different toxin contents and pour them into the liquid dispensing device;
(2)打开入口泵，使药液进入储液装置；(2) Turn on the inlet pump to make the liquid medicine enter the liquid storage device;
(3)在药液填充至设定条件时，打开出口泵、比例阀和开关，使药液在配液装置和储液装置之间循环，从配液装置流出，再从储液装置经管路、出口泵、开关回流到配液装置；(3) When the liquid medicine is filled to the set condition, open the outlet pump, proportional valve and switch, so that the liquid medicine circulates between the liquid dispensing device and the liquid storage device, flows out from the liquid dispensing device, and then flows from the liquid storage device through the pipeline , outlet pump, switch back to the liquid dispensing device;
(4)通过对温度控制装置和压力控制装置进行调节，模拟出人体血液循环时的温度及血压；(4) By adjusting the temperature control device and the pressure control device, the temperature and blood pressure during human blood circulation are simulated;
(5)打开开关，部分药液流入血透机的透析器的入口，透析后经过透析器出口和单向阀流回储液装置，从而模拟血液透析。(5) Turn on the switch, part of the medicinal liquid flows into the inlet of the dialyzer of the hemodialysis machine, and flows back to the liquid storage device through the outlet of the dialyzer and the one-way valve after dialysis, thereby simulating hemodialysis.
所述步骤(4)包括以下步骤：Described step (4) comprises the following steps:
(41)通过在出口泵与开关之间的温度传感器配合控制电路，对加热棒进行PID控制，使药液达到恒温状态；(41) The temperature sensor between the outlet pump and the switch cooperates with the control circuit to carry out PID control on the heating rod, so that the medicinal liquid reaches a constant temperature state;
(42)通过在出口泵、比例阀、开关之间的压力传感器配合控制电路，进行PWM控制，控制压力。(42) PWM control is performed to control the pressure by cooperating with the control circuit with the pressure sensor between the outlet pump, the proportional valve and the switch.
有益效果：与现有技术相比，本发明的有益效果：1、通过调节压力控制装置和温度控制装置模拟人体的血压及血液温度，使透析过程更真实，从而更好的检测透析效果；2、通过配置不同毒素含量的液体，来获取透析到一定标准下的时间，可以为患病种类不同程度不一的患者预估一次血液透析的时间，一定程度上减少了患者进行血液透析的安全隐患。Beneficial effects: Compared with the prior art, the beneficial effects of the present invention: 1. By adjusting the pressure control device and the temperature control device to simulate the blood pressure and blood temperature of the human body, the dialysis process is made more realistic, so as to better detect the dialysis effect; 2 . By configuring liquids with different toxin contents to obtain the time required for dialysis to reach a certain standard, the time for a hemodialysis can be estimated for patients with different types of diseases, which reduces the safety risks of patients undergoing hemodialysis to a certain extent. .
附图说明Description of drawings
图1为本发明的血透机透析效果检测系统结构图；Fig. 1 is a hemodialysis machine dialysis effect detection system structural diagram of the present invention;
图2为本发明血透机透析效果检测系统控制方法流程图。Fig. 2 is a flow chart of the control method of the dialysis effect detection system of the hemodialysis machine according to the present invention.
具体实施方式Detailed ways
下面结合附图对本发明作进一步阐述：Below in conjunction with accompanying drawing, the present invention is further elaborated:
如图1所示，一种检测血透机透析效果的系统，包括配液装置(1)、储液装置(2)、温度控制装置、压力控制装置、入口泵(4)、过滤器(5)、单向阀(6)、出口泵(7)、比例阀(8)、开关(9)和管路；配液装置(1)通过管路、入口泵(4)、过滤器(5)、单向阀(6)和储液装置进液口相连，储液装置出液口通过过滤器(5)、出口泵(7)、比例阀(8)和两个开关(9)分别和配液装置回流口及血透机透析器(3)入口相连，血透机透析器出口处通过管路、单向阀(6)和储液装置进液口相连，配液装置和储液装置形成环路，储液装置和血透机透析器形成环路；两个开关之间安装有温度控制装置和压力控制装置。As shown in Figure 1, a system for detecting the dialysis effect of a hemodialysis machine includes a liquid dispensing device (1), a liquid storage device (2), a temperature control device, a pressure control device, an inlet pump (4), and a filter (5). ), one-way valve (6), outlet pump (7), proportional valve (8), switch (9) and pipeline; the liquid dosing device (1) passes through pipeline, inlet pump (4), filter (5) , the check valve (6) is connected with the liquid inlet of the liquid storage device, and the liquid outlet of the liquid storage device is connected with the filter (5), the outlet pump (7), the proportional valve (8) and the two switches (9) respectively. The return port of the liquid device is connected to the inlet of the dialyzer (3) of the hemodialysis machine, and the outlet of the dialyzer of the hemodialysis machine is connected to the liquid inlet of the liquid storage device through a pipeline, a one-way valve (6), and the liquid dispensing device and the liquid storage device are formed. The loop, the liquid storage device and the hemodialysis machine dialyzer form a loop; a temperature control device and a pressure control device are installed between the two switches.
温度控制装置包括温度传感器(10)、装在配液装置的加热棒(12)，温度控制装置通过控制电路来进行输出温度的调节。压力控制装置由出口泵(7)、比例阀(8)、开关(9)、压力传感器(11)组成；比例阀(8)与出口泵(7)并联，压力传感器(11)在两个开关(9)中间；利用PWM技术控制比例阀(8)的开关频率，从而使得流入血透机的液体压力能够在小范围内上下跳动，液体经过血透机透析器后经过单向阀(7)回流到相当于静脉的储液装置(2)，储液装置中的压力基本稳定不变。The temperature control device comprises a temperature sensor (10) and a heating rod (12) mounted on the liquid dispensing device, and the temperature control device adjusts the output temperature through a control circuit. The pressure control device consists of an outlet pump (7), a proportional valve (8), a switch (9), and a pressure sensor (11); the proportional valve (8) is connected in parallel with the outlet pump (7), and the pressure sensor (11) is connected between the two switches. (9) Middle; PWM technology is used to control the switching frequency of the proportional valve (8), so that the pressure of the liquid flowing into the hemodialysis machine can jump up and down in a small range, and the liquid passes through the one-way valve (7) after passing through the dialyzer of the hemodialysis machine. Return to the fluid storage device (2) equivalent to the vein, and the pressure in the fluid storage device is basically stable and unchanged.
如图2所示，血透机透析效果检测系统的控制方法，包括以下步骤：As shown in Figure 2, the control method of the dialysis effect detection system of the hemodialysis machine includes the following steps:
(1)根据不同疾病的血液特征，配置不同毒素含量的药液，并倒入配液装置(1)中；(1) According to the blood characteristics of different diseases, prepare liquid medicines with different toxin contents, and pour them into the liquid dispensing device (1);
(2)打开入口泵(4)，使药液进入储液装置(2)；(2) Turn on the inlet pump (4), so that the medicinal liquid enters the liquid storage device (2);
(3)在药液填充至设定条件时，打开出口泵(7)、比例阀(8)和开关(9)，使药液在配液装置和储液装置之间循环，从配液装置(1)流出，再从储液装置(2)经管路、出口泵(7)、开关(9)回流到配液装置(1)；(3) When the liquid medicine is filled to the set condition, open the outlet pump (7), proportional valve (8) and switch (9), so that the liquid medicine circulates between the liquid dispensing device and the liquid storage device, from the liquid dispensing device (1) outflow, and then flow back from the liquid storage device (2) to the liquid dispensing device (1) through the pipeline, the outlet pump (7), and the switch (9);
(4)通过对温度控制装置和压力控制装置进行调节，模拟出人体血液循环时的温度及血压；(4) By adjusting the temperature control device and the pressure control device, the temperature and blood pressure during human blood circulation are simulated;
(5)打开开关(9)，部分药液流入血透机的透析器(3)的入口，透析后经过透析器出口和单向阀6)流回储液装置(2)，从而模拟血液透析。(5) Turn on the switch (9), part of the medicinal liquid flows into the inlet of the dialyzer (3) of the hemodialysis machine, and flows back to the liquid storage device (2) through the dialyzer outlet and the one-way valve 6) after dialysis, thereby simulating hemodialysis .
其中，步骤(4)是通过在出口泵(7)与开关(9)之间的温度传感器(10)配合相关控制电路，对加热棒(12)进行PID控制，从而进行恒温调节；通过在出口泵(7)、比例阀(8)、开关(9))和压力传感器(11)配合相关控制电路进行PWM控制，进行模拟动脉压力。Wherein, in step (4), the temperature sensor (10) between the outlet pump (7) and the switch (9) cooperates with the relevant control circuit to perform PID control on the heating rod (12), thereby performing constant temperature regulation; The pump (7), the proportional valve (8), the switch (9)) and the pressure sensor (11) cooperate with the relevant control circuit to perform PWM control to simulate arterial pressure.
在药液温度和压力都达到人体血液循环时的血液温度和血压，开始进行透析和数据的采集，下面对肌酐含量700umol/L的药液，进行透析，并采集数据实验进行两个小时，每半个小时采集一次，数据如表一所示：When the temperature and pressure of the medicinal solution reach the blood temperature and blood pressure of the human blood circulation, the dialysis and data collection begin. Next, the medicinal solution with a creatinine content of 700umol/L is subjected to dialysis, and the data collection experiment is carried out for two hours. Collected every half an hour, the data is shown in Table 1:
表一肌酐含量Table 1 Creatinine content
从表中可以看出，肌酐含量为700umol/L的药液，透析两个小时后肌酐含量下降至400umol/L，人体的肌酐最高安全含量是445umol/L，由此看来若是要求透析后的目标含量设置在445umol/L，那么透析时间为1.5小时效果最佳；若是目标含量设置在400umol/L则透析效果两小时最佳。It can be seen from the table that the creatinine content of the liquid with a creatinine content of 700umol/L drops to 400umol/L after two hours of dialysis, and the highest safe content of creatinine in the human body is 445umol/L. If the target content is set at 445umol/L, then the dialysis time is 1.5 hours, the best effect; if the target content is set at 400umol/L, the dialysis effect is the best for two hours.
Claims (4)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810095341.XA CN108379678B (en) | 2018-01-31 | 2018-01-31 | A hemodialysis machine dialysis effect detection system and its control method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810095341.XA CN108379678B (en) | 2018-01-31 | 2018-01-31 | A hemodialysis machine dialysis effect detection system and its control method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108379678A CN108379678A (en) | 2018-08-10 |
| CN108379678B true CN108379678B (en) | 2020-11-20 |
Family
ID=63074860
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810095341.XA Active CN108379678B (en) | 2018-01-31 | 2018-01-31 | A hemodialysis machine dialysis effect detection system and its control method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108379678B (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994016751A1 (en) * | 1993-01-28 | 1994-08-04 | Otsuka Pharmaceutical Factory, Inc. | Secondary filter cleaning method in blood plasma filtration method |
| CN104689395A (en) * | 2013-12-05 | 2015-06-10 | 天津市迈克尔化工有限公司 | Experimental facility for dialyzer ultrafiltration rate and clearance rate |
| CN205288119U (en) * | 2015-12-29 | 2016-06-08 | 苏州君康医疗科技有限公司 | Ultrafiltration coefficient clearance detection device |
| CN106693096A (en) * | 2016-12-30 | 2017-05-24 | 北京迈淩医疗技术发展有限公司 | Hemodialysis device and method capable of online measuring urea clearance index |
-
2018
- 2018-01-31 CN CN201810095341.XA patent/CN108379678B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994016751A1 (en) * | 1993-01-28 | 1994-08-04 | Otsuka Pharmaceutical Factory, Inc. | Secondary filter cleaning method in blood plasma filtration method |
| CN104689395A (en) * | 2013-12-05 | 2015-06-10 | 天津市迈克尔化工有限公司 | Experimental facility for dialyzer ultrafiltration rate and clearance rate |
| CN205288119U (en) * | 2015-12-29 | 2016-06-08 | 苏州君康医疗科技有限公司 | Ultrafiltration coefficient clearance detection device |
| CN106693096A (en) * | 2016-12-30 | 2017-05-24 | 北京迈淩医疗技术发展有限公司 | Hemodialysis device and method capable of online measuring urea clearance index |
Also Published As
| Publication number | Publication date |
|---|---|
| CN108379678A (en) | 2018-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6139529B2 (en) | Dialysate flow control | |
| CN101909671B (en) | Method for determining the percentage of recirculation in fistula and/or cardiopulmonary recirculation relative to total fistula recirculation and cardiopulmonary recirculation | |
| JP4546544B2 (en) | Apparatus and method for detecting complications during extracorporeal blood treatment | |
| CN101269246B (en) | Continuous blood cleaning equipment with replacement liquid purifier | |
| WO2018031711A2 (en) | Catheter and peritoneum health monitoring | |
| US20110004141A1 (en) | Method and arrangement for determining the recirculation in a fistula or the cardiopulmonary recirculation, and a blood treatment device comprising a device for determining the fistula recirculation or the cardiopulmonary recirculation part | |
| CN101184517A (en) | Automation and optimization of CRRT therapy with topical citrate anticoagulation | |
| JP2002159570A (en) | Measuring method of celiac internal capacity and peritoneum dialyzer | |
| JP5889896B2 (en) | Device and method for detecting the direction of fluid flow through a dialyzer | |
| CN108778361A (en) | The method and system of the obstruction in blood circuit for detecting dialysis system | |
| EP4073254A1 (en) | Extracorporeal blood treatment systems and methods employing batch processing | |
| CN111282063A (en) | Accurate peritoneal dialysis therapy based on dialysis sufficiency scale measurements | |
| CN203989201U (en) | A kind of based on Diapact CRRT machine and for the improved device of Cured by Double Filtration Plasmapheresis plasmapheresis | |
| US9895478B2 (en) | Hemodialysis on-line port leak detection | |
| CN104970767B (en) | Device and method for determining the distribution volume of a dialysis patient | |
| CN201186074Y (en) | Continuous blood purifying equipment with substitute fluid purifier | |
| CN108379678B (en) | A hemodialysis machine dialysis effect detection system and its control method | |
| AU2018352585B2 (en) | Techniques for detecting access recirculation | |
| CN204411383U (en) | Dialysis apparatus | |
| CN206518724U (en) | Citrate anticoagulation device | |
| CN211301424U (en) | A special blood purification system for children | |
| CN210750527U (en) | System for indirectly monitoring level of extracorporeal circulation ionized calcium | |
| CN209596288U (en) | Device for producing peritoneal dialysis fluid by diluting with concentrate | |
| CN106139286A (en) | A kind of regulation system for blood purification | |
| CN110975040A (en) | Blood purification system special for children and application of blood purification system in blood purification of children |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |