CN108364847A - A kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep - Google Patents
A kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep Download PDFInfo
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- CN108364847A CN108364847A CN201810040360.2A CN201810040360A CN108364847A CN 108364847 A CN108364847 A CN 108364847A CN 201810040360 A CN201810040360 A CN 201810040360A CN 108364847 A CN108364847 A CN 108364847A
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/022—Circuit arrangements, e.g. for generating deviation currents or voltages ; Components associated with high voltage supply
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
- G01N27/622—Ion mobility spectrometry
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Abstract
The invention discloses a kind of Fourier transformation ionic migration spectrometers of continuous frequency sweep, including square-wave signal generating means, the first and second ion gates and its driving circuit, square-wave signal generating means is used to generate the square-wave signal of frequency consecutive variations, and frequency range is from the initial frequency of scanning to termination frequency；Driving circuit includes the first and second driving circuits for being respectively used to the first and second ion door open-closes of driving；Wherein, first driving circuit and the second driving circuit are connected to square-wave signal generating means, and under the control of the square-wave signal in frequency consecutive variations, the opening-closing door drive signal of identical frequency consecutive variations is generated respectively so that the ON/OFF frequency of the first and second ion gates varies continuously to the termination frequency within the frequency sweep time by initial frequency.Compared with the sweep method of square wave frequency stepwise change, when obtaining the roughly the same spectrogram of quality, the frequency sweep time used in sweep method of the invention is substantially shorter.
Description
Technical field
The present invention relates to a kind of Fourier transformation ionic migration spectrometers of continuous frequency sweep more particularly to twice ion gate with frequency
The Fourier transformation ionic migration spectrometer of the same-phase square wave pattern switch of rate consecutive variations.
Background technology
Parameter involved in the frequency sweep process of traditional Fourier transformation ionic migration spectrometer has：Initial frequency terminates frequency
Rate (or swept frequency range) and sweep interval.During frequency sweep, the ON/OFF frequency of ion gate is incremented by a stepwise manner, often
Secondary step value is a sweep interval, carries out frequency sweep.Under each opening-closing door frequency, the ion detected in the rounding period is believed
Number average value, as the signal value under the frequency.After frequency sweep, obtain that abscissa is frequency, ordinate is signal mean value
Frequency domain spectrogram.The frequency domain spectrogram generates wave in time domain by inversefouriertransform, differentiates tested substance according to wave in time domain
Ingredient.For the sweep method of this stepping there is the frequency sweep time is long, efficiency is low, the deficiency of control program complexity etc..
The disclosure of background above technology contents is only used for auxiliary and understands present invention design and technical solution, not
The prior art for necessarily belonging to present patent application, no tangible proof show the above present patent application the applying date
Before have disclosed in the case of, above-mentioned background technology should not be taken to evaluation the application novelty and creativeness.
Invention content
It is a primary object of the present invention to propose a kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep, pass through frequency
The square-wave signal of consecutive variations controls the ON/OFF of ion gate, realizes continuous frequency sweep.
The technical solution that the present invention is proposed for the above-mentioned purpose is as follows：
A kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep, including square-wave signal generating means, first and second
Ion gate and its driving circuit, the square-wave signal generating means are used to generate the square-wave signal of frequency consecutive variations, wherein frequency
Rate variation range is from the initial frequency of scanning to termination frequency；The driving circuit include be respectively used to driving first and second from
First and second driving circuits of cervical orifice of uterus ON/OFF；Wherein, the first driving circuit and the second driving circuit are connected to the square wave
Signal generation apparatus, and under the control of the square-wave signal in the frequency consecutive variations, generate identical frequency respectively and continuously become
The opening-closing door drive signal of change so that the ON/OFF frequency of the first and second ion gates is within the frequency sweep time by the initial frequency
Vary continuously to the termination frequency.
The Fourier transformation ionic migration spectrometer for the continuous frequency sweep that above-mentioned technical proposal of the present invention is provided, compared to tradition
Fourier transformation ionic migration spectrometer, has the following advantages：
1), in the case where obtaining the spectrogram of phase homogenous quantities, when can simplify square-wave signal generation flow and shorten detection
Between；
2) during, overcoming step-by-step movement frequency sweep, computer need to constantly send command adapted thereto reality to square-wave signal generating means
The problem of existing frequency error factor, keep the process of frequency sweep simply time saving；
3), overcome step-by-step movement sweep method in frequency switching process, due to the discontinuity of signal, make start cycle or
The unserviceable problem of signal of end period, improves detection efficiency；
4), under the same frequency sweep time, continuous frequency sweep of the invention can obtain the spectrogram of swept frequency range bigger, obtain
Obtain higher sensitivity, resolution ratio and signal-to-noise ratio.
It is highly preferred that the frequency of the square-wave signal of the frequency consecutive variations is consecutive variations or from high to low from low to high
Consecutive variations.
Occur it is highly preferred that the square-wave signal generating means is a signal that can generate frequency consecutive variations square wave
Device.
It is highly preferred that the square-wave signal generating means is the microcontroller or control card for being embedded with computer program, hold
The row computer program is to generate the square-wave signal of the frequency consecutive variations.
It is highly preferred that first and second ion gate is BN ion gates or TP ion gates.
It is highly preferred that the opening-closing door pattern of first and second ion gate is monopole opening-closing door pattern.
It is highly preferred that the opening-closing door pattern of first and second ion gate is bipolar opening-closing door pattern.
Description of the drawings
Fig. 1 is the migration cavity schematic diagram of Fourier transformation ionic migration spectrometer；
Fig. 2 is the Fourier transformation ionic migration spectrometer that the square-wave signal based on frequency consecutive variations carries out continuous frequency sweep
Structural schematic diagram；
Fig. 3 is the spectrum that continuous sweep method is obtained with traditional step-by-step movement frequency sweep under identical frequency sweep time and sweep interval
Figure comparison；
Fig. 4 is the spectrum that continuous sweep method is obtained with traditional step-by-step movement frequency sweep under identical frequency sweep time and swept frequency range
Figure comparison.
Specific implementation mode
The invention will be further described with specific embodiment below in conjunction with the accompanying drawings.
The specific implementation mode of the present invention provides a kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep (aftermentioned can
Referred to as " FT-IMS "), as depicted in figs. 1 and 2, FT-IMS of the invention includes square-wave signal generating means 100, transference tube
10 and the first and second ion gates 13 and 14 in transference tube and its driving circuit 201,202.As shown in Figure 1,
Transference tube 10 is equipped with the in/out mouth of the entrance and drift gas 2 of carrier gas and sample gas 1, and inside is divided into ionized region 11 and moves
Area 12 is moved, inside sets gradually the first ion gate 13, the second ion gate 14, gauze screen 15 and faraday since ion entrance end
Disk 16；Faraday plate 16 is used as ion detector, and rear end is connected with a signal amplifier 20, AD capture cards 30 and computer in turn
40.Object sample gas to be detected is ionized to ion 400 when entering ionized region 11, when the first ion gate 13 is in its driving circuit 201
Driving under when opening, the ion 400 of ionized region can enter migration area 12 across the first ion gate 13, and in migration electric field
Under the action of migrated to the direction of the second ion gate, in migration area, the migration velocities of different ions is different, therefore, enters together
The time that the ion of migration area reaches Faraday plate 16 by the second ion gate 14 is different, and the kind of ion is distinguished according to this principle
Class.Detect that the signal of ion, signal are handled by signal amplifier 20, acquired by AD capture cards 30 by Faraday plate
It is sent into computer 40 afterwards, signal frequency domain spectrogram 500 can be obtained, specifically how according to frequency domain spectrogram and wave in time domain progress ion
Type and content detection then repeat no more, belong to general knowledge known in this field.
It is (continuous from low to high that the square-wave signal generating means 100 of the FT-IMS of the present invention can generate frequency consecutive variations
Variation or consecutive variations from high to low) square-wave signal 101, wherein frequency range is from the initial frequency of scanning to termination
Frequency, for example, swept frequency range is 1~5000Hz, then the frequency of the square-wave signal 101 varies continuously to 5000Hz from 1Hz, reference
Fig. 2, unlike traditional periodic square wave signal, the period is consecutive variations (constantly becoming smaller), a cycle
It is defined as from a rising edge to its adjacent next rising edge.
As shown in Fig. 2, driving circuit 201 and 202 is connected to square-wave signal generating means, and continuously become in the frequency
Under the control of the square-wave signal of change, the opening-closing door drive signal of identical frequency consecutive variations is generated respectively so that first and
The ON/OFF frequency of two ion gates varies continuously to the termination frequency within the frequency sweep time by the initial frequency.To realize
Continuous frequency sweep, compared with the mode of traditional step-by-step movement frequency sweep, the roughly the same spectrogram of spectrogram quality, then of the invention in order to obtain
Continuous sweep method used in the frequency sweep time greatly shorten, can realize rapid frequency-sweeping.
In one embodiment, the square-wave signal generating means is a signal hair that can generate frequency consecutive variations square wave
Raw device；Alternatively, microcontroller or control card programming can also be used to realize, to generate the square-wave signal of the frequency consecutive variations.
The present invention is not restricted the type of ion gate, can be BN ion gates, TP ion gates or other types of ion gate；To ion
The opening-closing door pattern of door is not also restricted, and can be monopole or bipolar opening-closing door pattern.
It is compared below by with traditional step-by-step movement sweep method, the advantages of to illustrate continuous sweep method of the invention.
Using frequency sweep of the invention continuous FT-IMS and traditional step-by-step movement frequency sweep FT-IMS respectively to same sample into
Row Scanning Detction.Carry out comparative illustration in two kinds of situation：
Situation 1, the frequency sweep time that two ways is arranged is identical with sweep interval to carry out ion scan, after the completion of scanning,
It was found that within the identical frequency sweep time, the swept frequency range (0~20000Hz) that the mode of the continuous frequency sweep of the present invention can scan is long-range
In the swept frequency range (0~5000Hz) of step-by-step movement sweep method；Then anti-Fourier's change is carried out respectively to obtained frequency domain spectrogram
It changes, obtains wave in time domain, as shown in Figure 3, it can be seen that：There are larger distortions for the spectrogram (time domain) of step-by-step movement sweep method
(high frequency points missing), spike is clearly, sufficiently oily；And the waveform of the spectrogram of the continuous frequency sweep of the present invention is more round and smooth, not
Apparent spike is had, there is higher accuracy of detection.
The frequency sweep time (being 0~20000Hz) identical with swept frequency range of two ways is arranged to carry out ion in situation 2
Scanning, when the sweep interval of the setting present invention is 10Hz, the sweep interval of step-by-step movement frequency sweep is 40Hz, right after the completion of scanning
Obtained frequency domain spectrogram carries out inversefouriertransform and obtains corresponding wave in time domain, as shown in Figure 4, it can be seen that：Step-by-step movement is swept
The spectrogram that the spectrogram that frequency mode obtains is obtained relative to continuous sweep method, there are certain signal distortions, and spectrogram quality is far not
The spectrogram obtained such as continuous sweep method.
The above content is a further detailed description of the present invention in conjunction with specific preferred embodiments, and it cannot be said that
The specific implementation of the present invention is confined to these explanations.For those skilled in the art to which the present invention belongs, it is not taking off
Under the premise of from present inventive concept, several equivalent substitute or obvious modifications can also be made, and performance or use is identical, all answered
When being considered as belonging to protection scope of the present invention.
Claims (7)
1. a kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep, including square-wave signal generating means, first and second from
Cervical orifice of uterus and its driving circuit, it is characterised in that：
The square-wave signal generating means is used to generate the square-wave signals of frequency consecutive variations, wherein frequency range is from sweeping
The initial frequency retouched to terminate frequency；The driving circuit includes be respectively used to the first and second ion door open-closes of driving the
One and second driving circuit；Wherein, the first driving circuit and the second driving circuit are connected to the square-wave signal generating means,
And under the control of the square-wave signal in the frequency consecutive variations, the opening-closing door for generating identical frequency consecutive variations respectively drives
Dynamic signal so that the ON/OFF frequency of the first and second ion gates varies continuously to institute within the frequency sweep time by the initial frequency
State termination frequency.
2. Fourier transformation ionic migration spectrometer as described in claim 1, it is characterised in that：The side of the frequency consecutive variations
The frequency of wave signal is consecutive variations or from high to low consecutive variations from low to high.
3. Fourier transformation ionic migration spectrometer as described in claim 1, it is characterised in that：The square-wave signal generating means
It is a signal generator that can generate frequency consecutive variations square wave.
4. Fourier transformation ionic migration spectrometer as described in claim 1, it is characterised in that：The square-wave signal generating means
It is the microcontroller or control card for being embedded with computer program, executes the computer program to generate the frequency consecutive variations
Square-wave signal.
5. such as Claims 1-4 any one of them Fourier transformation ionic migration spectrometer, it is characterised in that：First He
Second ion gate is BN ion gates or TP ion gates.
6. such as Claims 1-4 any one of them Fourier transformation ionic migration spectrometer, it is characterised in that：First He
The opening-closing door pattern of second ion gate is monopole opening-closing door pattern.
7. such as Claims 1-4 any one of them Fourier transformation ionic migration spectrometer, it is characterised in that：First He
The opening-closing door pattern of second ion gate is bipolar opening-closing door pattern.
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| CN201810040360.2A CN108364847A (en) | 2018-01-16 | 2018-01-16 | A kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep |
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| CN201810040360.2A CN108364847A (en) | 2018-01-16 | 2018-01-16 | A kind of Fourier transformation ionic migration spectrometer of continuous frequency sweep |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110176382A (en) * | 2019-06-04 | 2019-08-27 | 清华大学深圳研究生院 | A kind of ionic migration spectrometer ion gate switch door control method and ionic migration spectrometer |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4633083A (en) * | 1985-04-08 | 1986-12-30 | Washington State University Research Foundation, Inc. | Chemical analysis by time dispersive ion spectrometry |
| US20160284530A1 (en) * | 2015-03-24 | 2016-09-29 | Micromass Uk Limited | Absorption Mode FT-IMS |
| US20160282305A1 (en) * | 2015-03-24 | 2016-09-29 | Micromass Uk Limited | Method of FT-IMS |
| CN106098528A (en) * | 2016-06-14 | 2016-11-09 | 清华大学深圳研究生院 | A kind of apparatus and method reducing ionic migration spectrometer ion gate inductive kick |
| US20170074826A1 (en) * | 2015-09-15 | 2017-03-16 | Washington State University | Two-phase approach to fourier transform ion mobility time-of-flight mass spectrometry |
-
2018
- 2018-01-16 CN CN201810040360.2A patent/CN108364847A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4633083A (en) * | 1985-04-08 | 1986-12-30 | Washington State University Research Foundation, Inc. | Chemical analysis by time dispersive ion spectrometry |
| US20160284530A1 (en) * | 2015-03-24 | 2016-09-29 | Micromass Uk Limited | Absorption Mode FT-IMS |
| US20160282305A1 (en) * | 2015-03-24 | 2016-09-29 | Micromass Uk Limited | Method of FT-IMS |
| US20170074826A1 (en) * | 2015-09-15 | 2017-03-16 | Washington State University | Two-phase approach to fourier transform ion mobility time-of-flight mass spectrometry |
| CN106098528A (en) * | 2016-06-14 | 2016-11-09 | 清华大学深圳研究生院 | A kind of apparatus and method reducing ionic migration spectrometer ion gate inductive kick |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110176382A (en) * | 2019-06-04 | 2019-08-27 | 清华大学深圳研究生院 | A kind of ionic migration spectrometer ion gate switch door control method and ionic migration spectrometer |
| CN110176382B (en) * | 2019-06-04 | 2021-01-29 | 清华大学深圳研究生院 | Ion mobility spectrometer and ion gate opening and closing control method thereof |
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Application publication date: 20180803 |