CN108344697B - Special sample loading frame combination for in-vitro samples of photoacoustic tomography molecular imaging system - Google Patents
Special sample loading frame combination for in-vitro samples of photoacoustic tomography molecular imaging system Download PDFInfo
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- CN108344697B CN108344697B CN201810455848.1A CN201810455848A CN108344697B CN 108344697 B CN108344697 B CN 108344697B CN 201810455848 A CN201810455848 A CN 201810455848A CN 108344697 B CN108344697 B CN 108344697B
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- 238000003384 imaging method Methods 0.000 title claims abstract description 32
- 238000003325 tomography Methods 0.000 title claims abstract description 25
- 238000000338 in vitro Methods 0.000 title claims abstract description 22
- 239000004033 plastic Substances 0.000 claims abstract description 43
- 238000007789 sealing Methods 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 4
- 230000007423 decrease Effects 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 2
- 239000000523 sample Substances 0.000 description 51
- 238000001514 detection method Methods 0.000 description 8
- 239000004816 latex Substances 0.000 description 7
- 229920000126 latex Polymers 0.000 description 7
- 239000000463 material Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/1702—Systems in which incident light is modified in accordance with the properties of the material investigated with opto-acoustic detection, e.g. for gases or analysing solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N2021/0106—General arrangement of respective parts
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
Abstract
The invention discloses a special sample loading frame combination for an in-vitro sample of a photoacoustic tomography molecular imaging system, which comprises a sample loading frame main body and a sample loading tube, wherein the sample loading frame main body comprises a rectangular fixing plate, an elastic hollow plastic tube, a first support rod and a second support rod, the middle of the fixing plate is hollow, the first support rod and the second support rod are symmetrically and vertically fixed at the bottom of the fixing plate, the first support column and the second support rod extend towards the direction close to the perpendicular bisector of the fixing plate at the bottoms of the first support rod and the second support column, the plastic tube is horizontally fixed on the first support column, and the sample loading tube is detachably arranged between the plastic tube and the first support column.
Description
Technical Field
The invention relates to the technical field of photoacoustic imaging, in particular to a special sample loading frame combination for an in-vitro sample of a photoacoustic tomography molecular imaging system.
Background
Photoacoustic imaging is a noninvasive medical imaging method developed in recent years, and is an emerging imaging mode reflecting tissue structures according to the absorption distribution of biological tissues to light. The photoacoustic tomography molecular imaging system has extremely high application value in a plurality of fields of material science, oncology, cardiovascular, neurobiology, immunology, drug research and development and the like, and can realize the characteristic structure and the functional photoacoustic imaging of biological tissues with higher sensitivity. In research of materials or molecular imaging probes, the photoacoustic properties of the materials or probes are often required to be studied and determined before animal experiments, so that in-vitro sample detection, i.e. imaging detection of materials or molecular imaging probe solutions is required. The sample of the photoacoustic tomography molecular imaging system is placed in water for detection, which requires a special loading frame for matching the in-vitro sample.
The original sample loading rack of the manufacturer is a metal rack and a matched latex tube, two tiny cylinder hollow gaps are formed in the latex tube and used for sample loading, a second sample is added after the latex tube is cleaned during sample replacement, so that time is wasted when a plurality of samples are tested at the same time, pollution among the samples is easily caused due to the fact that the latex tube is not cleaned, and the latex tube is easy to age after being used repeatedly. If the latex tube of the original factory is used as a disposable latex tube, the cost is too high.
Disclosure of Invention
In order to solve the technical problems, the invention aims to provide a special sample loading frame combination for in-vitro samples of a photoacoustic tomography molecular imaging system, which can facilitate detection, save time and reduce mutual pollution between samples.
The invention provides an in-vitro sample special sample loading frame combination of a photoacoustic tomography molecular imaging system, which comprises a sample loading frame main body and a sample loading tube, wherein the sample loading frame main body comprises a rectangular fixing plate, an elastic hollow plastic tube, a first support column and a second support column, the middle of the fixing plate is hollow, the first support column and the second support column are symmetrically and vertically fixed at the bottom of the fixing plate, the first support column and the second support column extend towards the direction close to the perpendicular bisector of the fixing plate at the bottoms of the first support column, the plastic tube is horizontally fixed on the first support column, and the sample loading tube is detachably arranged between the plastic tube and the first support column.
Further, the plastic pipe is in a transverse conical shape, and the caliber of the plastic pipe gradually decreases towards the direction close to the perpendicular bisector of the fixing plate.
Further, one end of the plastic pipe is sleeved on the first support column, the sample tube is a hollow plastic transparent straight tube, the outer diameter of the sample tube is smaller than the minimum caliber of the plastic pipe, one end of the sample tube is detachably arranged in the other end of the plastic pipe in a penetrating mode, a positioning hole is formed in the middle of one end, far away from and towards the plastic pipe, of the second support column, and the other end of the sample tube is detachably positioned in the positioning hole.
Furthermore, the peripheral edges of the fixing plate are arc-shaped.
Further, the first support rod and the second support rod are located in the middle of two ends of the length direction of the hollowed-out part of the fixing plate.
Further, the loading frame body is made of metal.
Further, the caliber of one end of the plastic pipe is 20mm, and the caliber of the other end of the plastic pipe is 5mm.
Furthermore, one end of the sample loading pipe is detachably provided with a sealing cover, and the other end of the sample loading pipe is sealed.
Further, the sealing cover is a sealing film.
By means of the scheme, the invention has at least the following advantages: the special sample loading frame combination of the in-vitro sample of the photoacoustic tomography molecular imaging system can replace matched plastic transparent sample loading pipes within a few seconds, so that all samples are prepared at the same time and can be replaced at any time during testing, the matched plastic transparent sample loading pipes are very low in cost and can be used once, mutual pollution among the samples is completely avoided, repeated detection of the samples is facilitated, and in-vitro sample detection in the photoacoustic tomography molecular imaging system is more convenient.
The foregoing description is only an overview of the present invention, and is intended to provide a better understanding of the present invention, as it is embodied in the following description, with reference to the preferred embodiments of the present invention and the accompanying drawings.
Drawings
FIG. 1 is a schematic diagram of the structure of a sample-loading rack assembly for in vitro samples of a photoacoustic tomography molecular imaging system of the present invention;
FIG. 2 is a top view of a mounting plate according to the present invention;
FIG. 3 is a schematic view of the structure of the loading tube according to the present invention.
Description of the embodiments
The following describes in further detail the embodiments of the present invention with reference to the drawings and examples. The following examples are illustrative of the invention and are not intended to limit the scope of the invention.
Examples: the utility model provides a special application of sample shelf combination of external sample of optoacoustic tomography molecular imaging system, includes application of sample shelf main part and application of sample pipe 20, the application of sample shelf main part includes rectangular fixed plate 1, elasticity hollow plastic tubing 2 and first, two bracing pieces 3, 4, the centre of fixed plate is the fretwork form, first, two bracing pieces symmetry are vertical to be fixed the bottom of fixed plate, the bottom of first, two bracing pieces is all towards being close to the perpendicular to the direction of the perpendicular to the fixed plate extends has first, two support columns 5, 6, the plastic tubing level is fixed on the first support column, application of sample pipe demountable installation is in the plastic tubing with between the first support column.
The fixing plate can be arranged on the photoacoustic tomography molecular imaging system, and the condition of the sample in the upper sample tube can be conveniently observed through the middle hollowed-out part.
The plastic pipe is in a transverse conical shape, and the caliber of the plastic pipe gradually decreases towards the direction close to the perpendicular bisector of the fixing plate.
One end of the plastic pipe is sleeved on the first support column, the sample loading pipe is a hollow plastic transparent straight pipe, the outer diameter of the sample loading pipe is smaller than the minimum caliber of the plastic pipe, one end of the sample loading pipe can be detachably arranged in the other end of the plastic pipe in a penetrating mode, a positioning hole 7 is formed in the middle of one end, far away from and towards the plastic pipe, of the second support column, and the other end of the sample loading pipe can be detachably positioned in the positioning hole.
The edges and corners of the periphery of the fixing plate are arc-shaped.
The first support rod and the second support rod are positioned in the middle of two ends of the length direction of the hollowed-out part of the fixed plate.
The loading frame body is made of metal.
And one end of the plastic pipe is 20mm in caliber, and the other end of the plastic pipe is 5mm in caliber. Of course, the specific caliber size can be adjusted according to actual needs.
One end of the sample loading pipe is detachably provided with a sealing cover 8, and the other end of the sample loading pipe is sealed.
The sealing cover is a sealing film. Of course, both ends of the sample tube can be sealed by sealing films.
The special sample loading frame combination of the in-vitro sample of the photoacoustic tomography molecular imaging system can replace matched plastic transparent sample loading pipes within a few seconds, so that all samples are prepared at the same time and can be replaced at any time during testing, the matched plastic transparent sample loading pipes are very low in cost and can be used once, mutual pollution among the samples is completely avoided, repeated detection of the samples is facilitated, and in-vitro sample detection in the photoacoustic tomography molecular imaging system is more convenient.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, and it should be noted that it is possible for those skilled in the art to make several improvements and modifications without departing from the technical principle of the present invention, and these improvements and modifications should also be regarded as the protection scope of the present invention.
Claims (9)
1. The special sample loading frame combination for the in-vitro sample of the photoacoustic tomography molecular imaging system is characterized in that: including loading sample frame main part and last appearance pipe, loading sample frame main part includes rectangular fixed plate, elasticity hollow plastic tubing and first, two bracing pieces, the fixed plate is arranged in on the photoacoustic tomography molecular imaging system, the centre of fixed plate is the fretwork form, is convenient for observe the sample condition in the appearance pipe through middle fretwork department, first, two bracing pieces symmetry are vertical to be fixed the bottom of fixed plate, the bottom of first, two bracing pieces is all towards being close to the perpendicular to the direction extension of the perpendicular to the fixed plate has first, two support columns, the plastic tubing level is fixed on the first support column, loading sample pipe demountable installation is in the plastic tubing with between the first support column.
2. An in vitro sample-specific loading rack combination for a photoacoustic tomography molecular imaging system according to claim 1, wherein: the plastic pipe is in a transverse conical shape, and the caliber of the plastic pipe gradually decreases towards the direction close to the perpendicular bisector of the fixing plate.
3. An in vitro sample-specific loading rack combination for a photoacoustic tomography molecular imaging system according to claim 2, wherein: one end of the plastic pipe is sleeved on the first support column, the sample loading pipe is a hollow plastic transparent straight pipe, the outer diameter of the sample loading pipe is smaller than the minimum caliber of the plastic pipe, one end of the sample loading pipe can be detachably arranged in the other end of the plastic pipe in a penetrating mode, a positioning hole is formed in the middle of one end, far away from and towards the plastic pipe, of the second support column, and the other end of the sample loading pipe can be detachably positioned in the positioning hole.
4. A photoacoustic tomography molecular imaging system in vitro sample specific loading rack combination according to claim 3, wherein: the edges and corners of the periphery of the fixing plate are arc-shaped.
5. The in vitro sample application rack combination of a photoacoustic tomography molecular imaging system according to claim 4, wherein: the first support rod and the second support rod are positioned in the middle of two ends of the length direction of the hollowed-out part of the fixed plate.
6. An in vitro sample application rack assembly for a photoacoustic tomography molecular imaging system according to claim 5, wherein: the loading frame body is made of metal.
7. The in vitro sample application rack combination of a photoacoustic tomography molecular imaging system according to claim 6, wherein: and one end of the plastic pipe is 20mm in caliber, and the other end of the plastic pipe is 5mm in caliber.
8. The in vitro sample application rack combination of a photoacoustic tomography molecular imaging system according to claim 7, wherein: one end of the sample loading pipe is detachably provided with a sealing cover, and the other end of the sample loading pipe is sealed.
9. The in vitro sample application rack combination of a photoacoustic tomography molecular imaging system according to claim 8, wherein: the sealing cover is a sealing film.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810455848.1A CN108344697B (en) | 2018-05-14 | 2018-05-14 | Special sample loading frame combination for in-vitro samples of photoacoustic tomography molecular imaging system |
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| CN201810455848.1A CN108344697B (en) | 2018-05-14 | 2018-05-14 | Special sample loading frame combination for in-vitro samples of photoacoustic tomography molecular imaging system |
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| Publication Number | Publication Date |
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| CN108344697A CN108344697A (en) | 2018-07-31 |
| CN108344697B true CN108344697B (en) | 2024-02-09 |
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