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CN108325086A - A kind of method that smooth power promotes hair tonic, preparation and component - Google Patents

A kind of method that smooth power promotes hair tonic, preparation and component Download PDF

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Publication number
CN108325086A
CN108325086A CN201710046464.XA CN201710046464A CN108325086A CN 108325086 A CN108325086 A CN 108325086A CN 201710046464 A CN201710046464 A CN 201710046464A CN 108325086 A CN108325086 A CN 108325086A
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light
hair tonic
photosensitizer
light source
illumination
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CN108325086B (en
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王秀丽
王宏伟
张玲琳
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SHANGHAI DERMATOLOGY HOSPITAL
Huadong Hospital
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SHANGHAI DERMATOLOGY HOSPITAL
Huadong Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0616Skin treatment other than tanning
    • A61N5/0617Hair treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent

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  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Disclosed herein a kind of methods promoting hair tonic, include the following steps:Photosensitizer is applied on the skin;With the skin for using light irradiation to be coated with photosensitizer.The present invention is also disclosed that a kind of preparation for promoting hair tonic, including photosensitizer, wherein a concentration of the 3 20% of photosensitizer.The present invention is also disclosed that a kind of component for promoting hair tonic, including photosensitizer, for applying on the skin;Light source with certain wavelength;And optical controller, for controlling light source.

Description

一种光动力促进生发的方法,制剂和组件A method, preparation and component for photodynamically promoting hair growth

技术领域technical field

本发明涉及医疗器械技术领域,更具体地,本发明涉及一种应用光动力促进头发生长的方法,制剂和组件。The invention relates to the technical field of medical devices, and more specifically, the invention relates to a method, a preparation and a component for promoting hair growth by applying photodynamic force.

背景技术Background technique

光动力是通过外用光敏剂,事先使用靶组织含有光敏物质,再在特定的时间内应用特定波长的光照射,使光敏剂在吸收光子后产生一系列的光化学和光生物学反应,从而对组织造成损伤。Photodynamics is the use of external photosensitizers, the use of target tissues containing photosensitive substances in advance, and then the application of specific wavelengths of light for a specific period of time, so that the photosensitizers will produce a series of photochemical and photobiological reactions after absorbing photons, thereby causing damage to the tissues. damage.

光动力目前主要应用于治疗肿瘤和痤疮等。光动力用于更多的领域,还需要很多的探索,研究和实验。Photodynamics is currently mainly used in the treatment of tumors and acne. The use of photodynamics in more fields still needs a lot of exploration, research and experiments.

在光动力的使用中,有几个关键因素。首先特定组织的特征,对光敏剂的选择,还有对应光敏剂的光的选择,包括所选光的波长,光照量和光照时间。这些因素的协同作用决定光动力的应用领域和效果。本发明在此基础上做了一定的设想,实验和验证。In the use of light dynamics, there are several key factors. First, the characteristics of specific tissues, the selection of photosensitizer, and the selection of light corresponding to the photosensitizer, including the wavelength of the selected light, the amount of light and the time of light. The synergistic effect of these factors determines the application field and effect of photodynamics. The present invention has made certain assumptions, experiments and verifications on this basis.

发明内容Contents of the invention

本发明的一个目的是提供一种应用光动力促进头发生长的方法和组件。It is an object of the present invention to provide a method and assembly for promoting hair growth using photodynamics.

为达到上述目的,本发明提供了一种用于促进生发的制剂,包括光敏剂。To achieve the above object, the present invention provides a preparation for promoting hair growth, including a photosensitizer.

其中光敏剂的浓度为3-20%,并5-10%为较佳范围。Wherein the concentration of the photosensitizer is 3-20%, and 5-10% is the preferred range.

本其中光敏剂为5-氨基酮戊酸。The photosensitizer is 5-aminolevulinic acid.

本发明还揭露了一种促进生发的方法,包括以下步骤:将光敏剂涂在皮肤上;和使用光照射涂有光敏剂的皮肤。The invention also discloses a method for promoting hair growth, comprising the following steps: applying a photosensitizer to the skin; and irradiating the skin coated with the photosensitizer with light.

本发明还揭露了一种用于促进生发的组件,包括光敏剂,用于涂在皮肤上;具有一定波长的光源;和光控制器,用来控制光源。The invention also discloses a component for promoting hair growth, including a photosensitizer for coating on the skin; a light source with a certain wavelength; and a light controller for controlling the light source.

其中,光源为红光LED。Wherein, the light source is a red LED.

其中,所述光控制器包括能量设置模块,设置所述光源的照射能量值,和光强调节模块,用于调节所述光源的照射强度。Wherein, the light controller includes an energy setting module for setting the irradiation energy value of the light source, and a light intensity adjustment module for adjusting the irradiation intensity of the light source.

其中,所述光控制器包括计算模块,通过所述能量设置模块设定的能量值以及所述光强调节模块设定的光源的照射强度,计算得出每次光照所需要的时间。Wherein, the light controller includes a calculation module, which calculates the time required for each illumination through the energy value set by the energy setting module and the irradiation intensity of the light source set by the light intensity adjustment module.

其中,所述光控制器包括计时模块,与所述计算模块通信,所述计时模块收到所述计算模块计算出的所需光照时间后,开始计时,在计算得到的时间后自动关闭光源。Wherein, the light controller includes a timing module, which communicates with the calculation module, and the timing module starts timing after receiving the required illumination time calculated by the calculation module, and automatically turns off the light source after the calculated time.

本发明通过设想和实验证明可以有效的促进头发生长。The invention proves through assumptions and experiments that it can effectively promote hair growth.

附图说明Description of drawings

图1是本发明的促进生发组件示意图。Fig. 1 is a schematic diagram of the hair growth promoting component of the present invention.

图2是本发明的促进生发组件的光控制器组成框图。Fig. 2 is a block diagram of the composition of the light controller of the hair growth promoting component of the present invention.

具体实施方式Detailed ways

本发明揭露了一种应用光动力促进头发生长的制剂,包括光敏剂。其中光敏剂的浓度为3%-20%。较佳地,光敏剂的浓度为5%-10%的情况下,对人或动物的皮肤感受,及头发生长条件综合考虑较为有利。The invention discloses a preparation for promoting hair growth by applying photodynamic force, including a photosensitizer. Wherein the concentration of the photosensitizer is 3%-20%. Preferably, when the concentration of the photosensitizer is 5%-10%, it is more favorable for human or animal skin perception and hair growth conditions.

光敏剂在本实施例中具体使用外用光敏剂,具体可以为5-氨基酮戊酸(5-ALA),也可使用其它外用光敏剂。Photosensitizer In this embodiment, an external photosensitizer is specifically used, specifically 5-aminolevulinic acid (5-ALA), and other external photosensitizers can also be used.

本发明还揭露了一种促进生发的方法,该方法为将光动力应用于促进头发生长的方法。The invention also discloses a method for promoting hair growth, which is a method for applying photodynamic force to promote hair growth.

在本发明的一个实施例中,一种促进生发的方法具体包括以下步骤:将光敏剂涂在皮肤上;使用光照射涂有光敏剂的皮肤。In one embodiment of the present invention, a method for promoting hair growth specifically includes the following steps: applying a photosensitizer on the skin; and irradiating the skin coated with the photosensitizer with light.

对于光敏剂,可以使用3%-20%浓度的光敏剂,且浓度在5%-10%为最佳。光敏剂可以为等外用光敏剂,使用时首先将光敏剂,如5%浓度的5-氨基酮戊酸(5-ALA),涂在皮肤,如头皮上,并且涂敷一定时间后,然后使用光照射。For the photosensitizer, the photosensitizer can be used at a concentration of 3%-20%, and the best concentration is 5%-10%. The photosensitizer can be a photosensitizer for external use. When using it, first apply the photosensitizer, such as 5-aminolevulinic acid (5-ALA) with a concentration of 5%, to the skin, such as the scalp, and apply it for a certain period of time before using it. light exposure.

光敏剂涂敷时间范围可以根据效果以及人的承受时间调整,可为1.5-6小时,1.5-3小时较佳。光敏剂涂敷状态下,皮肤需要避光处理。The photosensitizer coating time range can be adjusted according to the effect and the tolerance time of people, which can be 1.5-6 hours, preferably 1.5-3 hours. When the photosensitizer is applied, the skin needs to be protected from light.

具体地说,在本实施例中,使用的光具有预定的能量值,较佳地,每次光照的能量在50-500J的范围。Specifically, in this embodiment, the light used has a predetermined energy value, preferably, the energy of each illumination is in the range of 50-500J.

在本实施例中,使用具有预定强度的光,光的强度选择皮肤可接受的范围。具体为50-500mw。In this embodiment, light with a predetermined intensity is used, and the intensity of the light is selected within a range acceptable to the skin. Specifically, it is 50-500mw.

每次照射的时间则根据使用光的能量和强度计算出来。计算公式为:The time of each irradiation is calculated according to the energy and intensity of the light used. The calculation formula is:

每次照射时间(s)=能量密度(J/cm2)/功率密度(W/cm2)Each irradiation time (s) = energy density (J/cm 2 )/power density (W/cm 2 )

在一个例子中,每次光照的能量设为60J,如果光强度设定为100mw或200mw,则需要的时间为10分钟或5分钟。In one example, the energy of each illumination is set to 60J, and if the light intensity is set to 100mw or 200mw, the required time is 10 minutes or 5 minutes.

在另一个例子中,每次光照的能量设为100J,如果光强度设定为100mw或200mw,则需要的时间为16分40秒或8分20秒。In another example, the energy of each illumination is set to 100J, if the light intensity is set to 100mw or 200mw, the required time is 16 minutes and 40 seconds or 8 minutes and 20 seconds.

光源的选择为目前常用的LED,具体为红光LED,也可为其它光源。The choice of the light source is currently commonly used LEDs, specifically red LEDs, or other light sources.

在一个实施例中,促进生发的方法还包括以下步骤,设定光源光照的能量,设定光源光照的强度,根据所述光照的能量和所述光照的强度计算出光照的时间,根据计算出光照的时间,计时所述光照的时间,在计时结束后,可通过关闭电源系统结束本次照射。In one embodiment, the method for promoting hair growth further includes the following steps: setting the energy of light source illumination, setting the intensity of light source illumination, calculating the time of illumination according to the energy of light illumination and the intensity of light illumination, and according to the calculated The time of illumination is to count the time of illumination. After the timing is over, the irradiation can be ended by turning off the power system.

在一个实施例中,促进生发的方法还包括以下步骤,通过远程控制,控制光源光照的能量,光源光照的强度,光照时间,光照间隔时间或频率。In one embodiment, the method for promoting hair growth further includes the step of controlling, by remote control, the energy of the light source, the intensity of the light source, the time of light, and the interval or frequency of light.

在一个实施例中,如图1所示,本发明还揭露了一种促进生发组件100,包括光敏剂10,用于涂在皮肤上;具有一定波长的光源20,用于照射涂有光敏剂的皮肤;和光控制器30,用来控制光源。In one embodiment, as shown in FIG. 1 , the present invention also discloses a hair growth promoting component 100, including a photosensitizer 10 for coating on the skin; a light source 20 with a certain wavelength for illuminating skin; and a light controller 30 for controlling the light source.

所述光敏剂10如前所述。所述光源20在本实施例中具体为红光LED,也可为其它光源。The photosensitizer 10 is as described above. The light source 20 is specifically a red LED in this embodiment, and may also be other light sources.

本实施例的促进生发组件100还包括电源系统,用于给所述光源20和光控制器30供电。The hair growth promoting component 100 of this embodiment further includes a power supply system for supplying power to the light source 20 and the light controller 30 .

如图2所示,所述光控制器30包括能量设置模块31,通过能量设置模块,可以设置光源每次照射光的能量值。As shown in FIG. 2 , the light controller 30 includes an energy setting module 31 , through which the energy value of the light irradiated by the light source each time can be set.

所述光控制器30还包括光强调节模块32,通过光强调节模块,可以调节使用光源的照射强度。The light controller 30 also includes a light intensity adjustment module 32, through which the illumination intensity of the light source can be adjusted.

所述光控制器30还包括计算模块33,通过所述能量设置模块31设定的能量值,以及通过所述光强调节模块32设定的光源强度,通过前述公式计算得出每次光照所需要的时间。The light controller 30 also includes a calculation module 33, the energy value set by the energy setting module 31, and the light source intensity set by the light intensity adjustment module 32 are calculated by the aforementioned formula to obtain time needed.

所述光控制器30还包括计时模块34,与所述计算模块33通信,计时模块收到计算模块计33算出的所需光照时间后,开始计时,在计算得到的时间后关闭光源。其中可以通过自动关闭电源系统来关闭光源,本次工作时间结束。计时模块还可以设定每次照射的时间间隔,在医生建议的时间间隔后自动开启电源系统,下次照射工作开始。The light controller 30 also includes a timing module 34, which communicates with the calculation module 33. The timing module starts timing after receiving the required illumination time calculated by the calculation module 33, and turns off the light source after the calculated time. Among them, the light source can be turned off by automatically turning off the power supply system, and the current working time is over. The timing module can also set the time interval of each irradiation, and automatically turn on the power system after the time interval suggested by the doctor, and the next irradiation work will start.

在一个实施例中,本发明的促进生发的组件还包括无线通信装置35,所述无线通信装置与光控制器30连接,专业人士可以通过远程控制,与无线通信装置取得连接,并通过输送信号给光控制器来控制光的能量,强度,照射时间,时间间隔,和频率等。In one embodiment, the component for promoting hair growth of the present invention also includes a wireless communication device 35, which is connected to the light controller 30, and professionals can obtain a connection with the wireless communication device through remote control, and transmit signals Give the light controller to control the energy, intensity, irradiation time, time interval, and frequency of the light.

本发明的促进生发的组件还包括遮光罩50,由遮光材料制成,周边装有弹性装置,用于收缩遮光材料,从而达到使涂有光敏剂的皮肤避光的效果。在一个实施例中,遮光罩为遮光头罩,为遮光的柔软材料制成头罩。周围固定松紧带,使遮光头罩能够紧紧的罩在头上。The hair growth promoting component of the present invention also includes a shading cover 50, which is made of shading material and is equipped with elastic devices around it for shrinking the shading material, so as to achieve the effect of protecting the skin coated with the photosensitizer from light. In one embodiment, the sunshield is a sunshield hood made of light-shielding soft material. Fasten the elastic band around so that the shade hood can fit tightly on the head.

本发明的促进生发的组件还包括头戴60,包括支架61,可支撑在头上,内部嵌有多个红光LED光源,用于对头皮进行照射。头罩可为硬质材料制成,能够支撑光源。The hair growth promoting component of the present invention also includes a headgear 60, including a bracket 61, which can be supported on the head, and a plurality of red LED light sources are embedded inside for irradiating the scalp. The hood can be made of a hard material capable of supporting the light source.

实施例1Example 1

使用浓度5%的5-氨基酮戊酸涂敷在头皮上3小时,然后使用630mm红光,光强度为200mw,照射5分钟。每周照射一次,6月后,头发的根数明显增长,头发直径也有所增加。Apply 5-aminolevulinic acid with a concentration of 5% on the scalp for 3 hours, and then use 630mm red light with a light intensity of 200mw for 5 minutes. After irradiating once a week, after 6 months, the number of hair roots increased significantly, and the diameter of the hair also increased.

实施例2Example 2

使用浓度10%的5-氨基酮戊酸涂敷在头皮上3小时,然后使用光强度为100mw,照射16分钟40秒。每周照射一次,6月后,头发的根数明显增长,头发直径也有所增加。Apply 5-aminolevulinic acid with a concentration of 10% on the scalp for 3 hours, and then use a light intensity of 100mw to irradiate for 16 minutes and 40 seconds. After irradiating once a week, after 6 months, the number of hair roots increased significantly, and the diameter of the hair also increased.

本发明用光照射涂有光敏剂的皮肤,使抑制毛发生长的皮脂腺选择性缩小,从而有效地促进生发。The invention uses light to irradiate the skin coated with the photosensitizer to selectively shrink the sebaceous glands that inhibit hair growth, thereby effectively promoting hair growth.

上述实施例能够有效地解决本发明提出的技术问题,熟悉本领域的技术人员都应该明白,本发明包括但不限于附图和具体实施方式中描述到的具体内容,任何不偏离本发明构思的技术方案都在本申请权利要求书的保护范围中。The above-described embodiments can effectively solve the technical problems proposed by the present invention, and those skilled in the art should understand that the present invention includes but is not limited to the specific content described in the accompanying drawings and specific implementation methods, and any content that does not deviate from the concept of the present invention The technical solutions are all within the protection scope of the claims of the present application.

Claims (10)

1. a kind of preparation promoting hair tonic, which is characterized in that including the photosensitizer that concentration range is 3-20%.
2. the preparation of the promotion hair tonic as described in right item 1, which is characterized in that the photosensitizer is 5-ALA.
3. a kind of method promoting hair tonic, which is characterized in that apply light dynamic method.
4. a kind of method promoting hair tonic, which is characterized in that include the following steps:
Photosensitizer is applied on the skin;With
The skin of photosensitizer is coated with using light irradiation.
5. the method for the promotion hair tonic as described in right item 4, including step:The energy for setting the illumination sets the strong of illumination Degree, according to the time that the energy of the illumination and the Strength co-mputation light extraction of the illumination are shone, according to the time for calculating illumination, meter The time of Shi Suoshu illumination terminates irradiation after timing.
6. a kind of component promoting hair tonic, which is characterized in that including
Photosensitizer, for applying on the skin;
Light source with certain wavelength;With
Optical controller, for controlling light source.
7. the component of the promotion hair tonic as described in right item 6, which is characterized in that light source is red-light LED.
8. the component of the promotion hair tonic as described in right item 7, which is characterized in that the optical controller includes energy setup module, The irradiation energy value and light intensity regulating module of the light source, the exposure intensity for adjusting the light source are set.
9. the component of the promotion hair tonic as described in right item 8, which is characterized in that the optical controller includes computing module, is passed through The exposure intensity of the energy value of the energy setup module setting and the light source of light intensity regulating module setting, is calculated Each illumination required time.
10. the component of the promotion hair tonic as described in right item 9, which is characterized in that the optical controller includes timing module, with institute It states computing module communication and starts timing after the timing module receives the calculated required light application time of the computing module, Light source is automatically closed after the time being calculated.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111135474A (en) * 2020-01-19 2020-05-12 上海市皮肤病医院 Photodynamic instrument, using method and photosensitizer processing method

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