CN108324407B - A porous biomimetic skull repair structure based on additive manufacturing technology - Google Patents

Abstract

The invention discloses a porous bionic skull repairing structure based on an additive manufacturing technology, which comprises an outer fixing sheet and an inner fixing sheet, wherein the outer fixing sheet and the inner fixing sheet are connected through a connecting piece.

Description

A porous biomimetic skull repair structure based on additive manufacturing technology

technical field

The invention relates to the field of medical technology, in particular to a porous bionic skull repair structure based on additive manufacturing technology.

Background technique

Cranioplasty is a common operation in neurosurgery. At present, most of these operations use artificial skulls to replace the missing parts of the skull. The most commonly used artificial skull material is titanium alloy mesh. With the improvement of people's living standards, people not only In order to achieve anatomical and physiological restoration through cranial repair, the requirements for appearance and beauty are getting higher and higher. In order to make the prosthetic body fit more perfectly with the patient's original skull, the previous reconstruction surgery was generally performed by doctors before or after surgery. According to the size and shape of the patient's defect, the titanium alloy mesh plate is manually knocked out, and after comparison on the patient's head, it is repeatedly trimmed, cut and sewed until it meets the requirements of the patient's defect, and finally fixed with screws. The shape of the patient’s skull defect was restored on the operating table as soon as possible. However, since the shape of each patient’s skull defect is different, the repair material titanium alloy mesh plate is not easy to shape, and repeated shaping is required during the operation, which increases the operation time. Time, although the appearance of the three-dimensional titanium plate makes the plastic deformation easier and shortens the operation time, but its hardness is not as good as the two-dimensional titanium plate. Moreover, the temperature conductivity of the titanium alloy stencil is strong, and it is easily affected by the external temperature to cause intracranial discomfort in patients. The edge of the titanium alloy stencil is sharp, and patients with thin scalp are prone to complications such as scalp pain after surgery. Titanium alloy mesh Cutting the scalp with the edge of the board can cause a CSF leak or even infection.

Based on this, research and design a porous bionic skull repair structure based on additive manufacturing technology.

Contents of the invention

The technical problem to be solved by the present invention is: when the existing skull implant structure is implanted, the hardness is low, it is easy to sag, and it is easily affected by the external temperature, which makes the patient feel uncomfortable when using it. The fixation sheet and the internal fixation sheet are composite layer structures, and there are connectors between them. The connectors themselves have a degradable effect. While increasing the strength of the skull implant, it is possible to avoid intracranial discomfort of the patient as much as possible.

The present invention realizes through following technical scheme:

A porous biomimetic skull repair structure based on additive manufacturing technology, including an external fixation piece and an internal fixation piece, the external fixation piece and the internal fixation piece are connected by a connecting piece, and the external fixation piece includes a first polymethacrylate Ester layer, the second polymethyl methacrylate layer, the first titanium alloy mesh, the second titanium alloy mesh, the first titanium alloy mesh is located at the upper end of the second titanium alloy mesh, the first polymethyl methacrylate layer is set on The upper end of the first titanium alloy mesh, the second polymethyl methacrylate layer is arranged on the lower end of the second titanium alloy mesh, the first polymethyl methacrylate layer, the second polymethyl methacrylate layer, the first titanium The alloy mesh and the second titanium alloy mesh are both arched mesh structures, the first polymethyl methacrylate layer has an elliptical cross-section structure, and the outer periphery of the first polymethyl methacrylate layer is provided with four Connecting plates, the four connecting plates are centrally symmetrical with the central axis of the first polymethyl methacrylate layer as the axis, and a Morse taper foot is connected to the ends of the four connecting plates; the internal fixation piece includes hydroxyapatite The repair layer, the titanium alloy repair layer, the hydroxyapatite repair layer is located on the upper end of the titanium alloy repair layer, the titanium alloy repair layer is provided with mesh holes, and the hydroxyapatite repair layer is respectively provided with the second An insertion block, a second insertion block, and the two ends of the short axis of the hydroxyapatite repair layer are respectively provided with a first through hole and a second through hole, and the first through hole and the second through hole are inserted with hydroxyl Titanium nail fixed with apatite repair layer and titanium alloy repair layer.

Further, the second polymethyl methacrylate layer, the first titanium alloy mesh, the second titanium alloy mesh, and the first polymethyl methacrylate layer are parallel to each other, and the first polymethyl methacrylate The curvature of the ester layer is 30-45°.

Further, the central angle at which the extension lines of the four connecting plates intersect is 90°.

Further, the first insert block and the second insert block are center-symmetrical to the central axis of the hydroxyapatite repair layer.

Further, the first polymethyl methacrylate layer is provided with round holes, and the diameter of the round holes is 50-300um.

Further, the connecting piece includes a first connecting rod, a second connecting rod, a first tapered portion, a second tapered portion, a third connecting rod, and a fourth connecting rod, one end of the first connecting rod is connected to the outer The lower surface of the fixed piece is detachably connected, and the other end of the first connecting rod is detachably connected to the first tapered part. The cross section of the first tapered part is circular, and the diameter of the circle decreases sequentially from top to bottom. The lower end of a tapered part is connected with the third connecting rod.

Further, one end of the second connecting rod is connected to the upper surface of the inner fixed piece, the other end of the second connecting rod is connected to the second tapered part, and the structure of the second tapered part is the same as that of the first tapered part. Similarly, the first tapered portion is connected to the fourth connecting rod, and the third connecting rod is detachably connected to the fourth connecting rod.

Further, the third connecting rod has a circular cross section, the fourth connecting rod is a hollow structure with an open upper end, the third connecting rod is inserted into the fourth connecting rod, and the third connecting rod is connected to the first connecting rod. The shapes of the four connecting rods are adapted and are threaded, the inner surface of the fourth connecting rod is provided with internal threads, the outer surface of the third connecting rod is provided with external threads, and the longitudinal length of the third connecting rod is less than or equal to the fourth connecting rod. The longitudinal length of the connecting rod.

Further, the cross section of the Morse taper foot is oval, and the material of the Morse taper foot is titanium alloy.

Further, the first insertion block is a curved long plate-shaped structure, and the structure of the first insertion block is the same as that of the second insertion block.

The present invention has following advantage and beneficial effect:

(1) In the present invention, the external fixation piece is creatively designed as a composite layer structure, and the composite layer includes a first polymethyl methacrylate layer, a second polymethyl methacrylate layer, a first titanium alloy mesh, a second titanium alloy mesh, and a second titanium alloy mesh. Alloy mesh, the first polymethyl methacrylate layer and the second polymethyl methacrylate layer are the outermost of the bone implant, which is not easily affected by the external temperature, and can effectively reduce the edge sharpness of the titanium alloy mesh plate. Reduce the occurrence of complications such as scalp pain in patients.

(2) In the present invention, the internal fixation piece is designed as a composite layer structure. The composite layer is an integrally formed structure of a hydroxyapatite repair layer and a titanium alloy repair layer. After the hydroxyapatite repair layer is implanted in the body, calcium and phosphorus are freed It is absorbed by body tissue and induces new bone tissue growth, and the titanium alloy repair layer is set to enhance the strength of the implanted structure, ensure a certain degree of support for the shape of the damaged tissue, and enable the repaired tissue to maintain a certain shape , to maintain the normal curved shape of the head.

(3) In the present invention, connectors are used to connect the external fixation piece and the internal fixation piece, and the connection is carried out in a detachable connection mode. The shapes of the external fixation piece and the internal fixation piece are the same as those of the surface of the defect tissue, and the external fixation piece is located in the defect tissue. The outer surface of the tissue, while the internal fixation piece is set on the inner surface of the defective tissue, and the setting of the intermediate connector can fix the implanted tissue after the defect, which is beneficial to the growth around the connector of the defective tissue and improves tissue compatibility.

Description of drawings

The drawings described here are used to provide a further understanding of the embodiments of the present invention, constitute a part of the application, and do not limit the embodiments of the present invention. In the attached picture:

Fig. 1 is a structural representation of the present invention,

Fig. 2 is a schematic structural view of the internal fixation sheet in the present invention;

Fig. 3 is the structural representation of connector among the present invention;

Marks and corresponding parts names in the attached drawings:

1-1—external fixation piece, 1—the first polymethyl methacrylate layer, 2—the second polymethyl methacrylate layer, 3—the first titanium alloy mesh, 4—the second titanium alloy mesh, 5— Morse taper foot, 7—connecting plate, 8—connecting piece, 82—first connecting rod, 83—first tapered part, 84—third connecting rod, 85—fourth connecting rod, 86—second cone part, 87—second connecting rod, 9—internal fixation piece, 91—hydroxyapatite repair layer, 92—first insertion block, 93—second insertion block, 94—first through hole, 95—second through hole Hole, 97—titanium alloy repair layer, 11—round hole.

Detailed ways

In order to make the purpose, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the examples and accompanying drawings. As a limitation of the present invention.

Example 1:

As shown in Figure 1, Figure 2, and Figure 3, a porous bionic skull repair structure based on additive manufacturing technology, including an external fixation piece 1-1, an internal fixation piece 9, an external fixation piece 1-1 and an internal fixation piece 9 They are connected by a connecting piece 8, and the external fixation sheet 1-1 includes a first polymethyl methacrylate layer 1, a second polymethyl methacrylate layer 2, a first titanium alloy mesh 3, a second titanium alloy Net 4, the first titanium alloy net 3 is located at the upper end of the second titanium alloy net 4, the first polymethyl methacrylate layer 1 is arranged on the upper end of the first titanium alloy net 3, the second polymethyl methacrylate layer 2 Set at the lower end of the second titanium alloy mesh 4, the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 are all arched The net plate structure, the first polymethyl methacrylate layer 1 is an oval structure in cross section, the outer periphery of the first polymethyl methacrylate layer 1 is provided with four connection plates 7, four connection plates 7 with The central axis of the first polymethyl methacrylate layer 1 is axisymmetric, and the ends of the four connecting plates 7 are connected with a Morse taper foot 5; the internal fixation piece 9 includes a hydroxyapatite repair layer 91 1. Titanium alloy repair layer 97, the hydroxyapatite repair layer 91 is located at the upper end of the titanium alloy repair layer 97, the titanium alloy repair layer 97 is provided with mesh holes, and the hydroxyapatite repair layer 91 is located at both ends of the long axis respectively A first insertion block 92 and a second insertion block 93 are provided, and the two ends of the short axis on the hydroxyapatite repair layer 91 are respectively provided with a first through hole 94 and a second through hole 95. The first through hole 94, Titanium nails for fixing the hydroxyapatite repair layer 91 and the titanium alloy repair layer 97 are inserted into the second through holes 95 .

In this embodiment, the skull repair structure is improved, and it is designed as a composite layer structure. The external fixation piece 1-1 is composed of the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy Mesh 3 and second titanium alloy mesh 4, the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 are all located in the repair tissue Therefore, the first polymethyl methacrylate layer 1 and the second polymethyl methacrylate layer 2 are in direct contact with the skin. These two layers have a mesh layer structure, and the material used is polymethyl methacrylate Polymethyl methacrylate, commonly known as plexiglass, is a transparent thermoplastic material that has the advantages of light weight, low price, and strong plasticity. When it is applied, it can be instantly shaped according to the shape of the bone defect and firmly fixed. And polymethyl methacrylate is synthesized from two components, specifically, the solid powder polymer component and liquid polymethacrylate are mixed according to the ratio of 2:1, polymerization reaction occurs and solidifies, so polymethacrylic acid is prepared When methyl ester is used as the material of the repair structure in contact with the skin, it is not easily affected by the external temperature, and it can avoid problems such as scalp pain in patients with thin scalp after surgery. Therefore, the material of the outer two layers is preferably polymethyl methacrylate. And the structure of the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 is an arched mesh structure, that is, the above-mentioned structural layer The central part of the skull is arched upwards, and this curved shape can be closely attached to the injured tissue of the skull, improving the compatibility with the tissue of the human body.

In the present embodiment, four connection plates 7 are arranged on the periphery of the first polymethyl methacrylate layer 1, and the four connection plates 7 are center-symmetrical with the central axis of the first polymethyl methacrylate layer. The connecting plates 7 are all connected with one Morse taper foot 5. The setting of the Morse taper foot 5 can closely cooperate with the bone hole, promote the growth of blood and flesh around the repair tissue, and reduce infectivity. At the same time, the four Morse taper feet 5 The heights are the same, and greater than the sum of the overall heights of the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4, and the Morse taper The lower end of the foot 5 extends to the lower end of the second polymethyl methacrylate layer 2, therefore, the four Morse taper feet 5 can support the external fixation piece 1-1, improving the strength and stability of the implanted structure.

In this embodiment, the internal fixation piece 9 includes a hydroxyapatite repair layer 91 and a titanium alloy repair layer 97, which are located on the inner surface of the repair tissue. The material used for the hydroxyapatite repair layer 91 is hydroxyapatite, and its molecular structure Compared with calcium scale, it is very similar to the inorganic components in normal bone, and has good biocompatibility, osteoconductivity and osteoinductivity. After implanted in the body, calcium and phosphorus will be released from the surface of the material to be absorbed by body tissues and induce new bone tissue growth. Through computer-aided three-dimensional simulation design technology, hydroxyapatite can be prefabricated into personalized implants according to the size and shape of the defect before operation. At the same time, considering that hydroxyapatite degrades too quickly in the body, it is combined with the titanium alloy repair layer. The use of titanium alloy repair layer 97 is conducive to shaping according to the shape of the cranio-maxillofacial defect, and it is firmly fixed. Stone repair layer 1 is used together to increase the stability of the implant and reduce the chance of infection.

Moreover, in this embodiment, a first through hole 94 and a second through hole 95 are set, and titanium nails are inserted into the two through holes to fix the hydroxyapatite repair layer 1 and the titanium alloy repair layer 7 to enhance the shaping effect .

In this embodiment, the outer fixation piece 1-1 and the inner fixation piece 9 are connected by a connecting piece 8, and a detachable connection method is adopted between the connecting piece 8 and the outer fixing piece 1-1 and the inner fixing piece 9, and the connecting piece can be It is made of hydroxyapatite material, which has degradability. After being implanted in the body for a period of time, it can degrade by itself, reducing the foreign body sensation of the repair structure in the body.

Example 2:

This embodiment is further defined on the basis of Example 1: the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, the second titanium alloy mesh 4, the first polymethyl methacrylate layer 1 are parallel to each other, the bending radian of the first polymethyl methacrylate layer 1 is 30-45°, and the central angle at which the extension lines of the four connecting plates 7 intersect is 90°, the first polymethyl methacrylate layer 1 The methyl acrylate layer 1 is provided with a round hole 95, and the diameter of the round hole 95 is 50-300um. In this embodiment, by setting the bending radian of the first polymethyl methacrylate layer 1 to be 30-45°, due to the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 , The first polymethyl methacrylate layer 1 is parallel to each other, then the bending arc of the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 is the same as that of the first polymethyl methacrylate layer. The bending arc of the methyl acrylate layer 1 is the same, and the first polymethyl methacrylate layer 1, the second polymethyl methacrylate layer 2, the first titanium alloy mesh 3, and the second titanium alloy mesh 4 are connected to each other by The structure forms an integral structure, which improves the fit between the upper and lower surfaces of the bone implant and the damaged skin, and at the same time reduces the problems of infection complications due to poor contact biocompatibility. And in this embodiment, the first polymethyl methacrylate layer 1 , the second polymethyl methacrylate layer 2 , the first titanium alloy mesh 3 , and the second titanium alloy mesh 4 are integrally formed. And the first titanium alloy mesh 3 and the second titanium alloy mesh 4 are set between the first polymethyl methacrylate layer 1 and the second polymethyl methacrylate layer 2, then the first titanium alloy mesh 3 and the second titanium alloy mesh The structure adopted by the alloy mesh 4 is a mesh plate structure, and the material used is medical titanium alloy, which has good biocompatibility and high mechanical strength, and can resist secondary trauma. Titanium nails for fixation. However, in this embodiment, the setting of the positions of the first titanium alloy mesh and the second titanium alloy mesh does not touch the skin, reduces infection complications, and improves the strength and support of the entire bone implant.

Example 3:

This embodiment is further defined on the basis of the above embodiments: the first inserting block 92 and the second inserting block 93 are center-symmetrical to the central axis of the hydroxyapatite repair layer 1 . Moreover, the first inserting block 92 is a curved long plate-shaped structure, and the structure of the first inserting block 92 and the second inserting block 93 are the same.

In this embodiment, the first inserting block 92 and the second inserting block 93 are set to facilitate fixing the overall structure formed by the hydroxyapatite repair layer 1 and the titanium alloy repair layer 7, so as to be able to connect with the craniomaxillofacial damaged tissue. good contact. In addition, in this embodiment, the shape of the first insertion block is preferably a curved long strip structure, which is beneficial to good contact between the first insertion block and the second insertion block and surrounding tissues.

Example 4:

This embodiment is further defined on the basis of the above embodiments, the connecting member 8 includes a first connecting rod 82 , a second connecting rod 87 , a first tapered portion 83 , a second tapered portion 86 , and a third connecting rod 84 , the fourth connecting rod 85, one end of the first connecting rod 82 is detachably connected to the lower surface of the outer fixing piece 1-1, the other end of the first connecting rod 82 is detachably connected to the first tapered portion 83, the second A tapered portion 83 has a circular cross section, and the diameter of the circle decreases sequentially from top to bottom. The lower end of the first tapered portion 83 is connected to the third connecting rod 84 .

In this embodiment, the specific structure of the connectors, the first connecting rod 82 and the second connecting rod 87, when connecting with the inner fixing piece 9 and the outer fixing piece 1-1 respectively, adopt a detachable connection mode, which is beneficial to installation, and the inner fixing piece 9. A plurality of connector structures can be set between the external fixation piece 1-1. While achieving the fixation of the defective tissue, the internal fixation piece 9 and the external fixation piece 1-1 are also a kind of fixation, enhancing the shaping effect .

In the present embodiment, the setting of the first tapered portion 83, the second tapered portion 86, the third connecting rod 84, and the fourth connecting rod 85 form an integral connector structure, which has the inner fixing piece 9, the outer fixing piece Sheet 1-1 is effectively connected and has a certain strength. The connection between the third connecting rod 84 and the fourth connecting rod 85 is a detachable connection, which is beneficial to the stable connection between the inner fixing piece 9 and the outer fixing piece 1-1.

Example 5:

This embodiment is further defined on the basis of the above embodiments, one end of the second connecting rod 87 is connected to the upper surface of the inner fixed piece 9, the other end of the second connecting rod 87 is connected to the second tapered portion 86, the second The structure of the second tapered portion 86 is the same as that of the first tapered portion 83 , the first tapered portion 83 is connected to the fourth connecting rod 85 , and the third connecting rod 84 is detachably connected to the fourth connecting rod 85 . The third connecting rod 84 is a circular structure in cross section, the fourth connecting rod 5 is a hollow structure with an open upper end, the third connecting rod 84 is inserted into the inside of the fourth connecting rod 85, and the third connecting rod 84 It is adapted to the shape of the fourth connecting rod 85 and is threaded. The inner surface of the fourth connecting rod 85 is provided with internal threads, the outer surface of the third connecting rod 84 is provided with external threads, and the third connecting rod 84 is provided with external threads. The longitudinal length is less than or equal to the longitudinal length of the fourth connecting rod 85 .

In this embodiment, the connection mode of the third connecting rod 84 and the fourth connecting rod 85 in the connector is specifically optimized. This threaded connection method is preferred, and when the third connecting rod is inserted into the inside of the fourth connecting rod, the two The connection between them is stable. At the same time, considering the tissue compatibility, the surface of the entire connector structure can be coated with hydroxyapatite coating. The composition of the hydroxyapatite coating is very similar to the inorganic components in normal bones, and has good biocompatibility , osteoconductivity and osteoinductivity. After implanted in the body, calcium and phosphorus will be released from the surface of the material to be absorbed by body tissues and induce new bone tissue growth.

At the same time, the structure of the connector itself can also be made of hydroxyapatite, which is beneficial to the degradation of the connector after implantation for a period of time, and the degradation time can be preferably limited. After a period of time of implantation, the internal fixation piece has been effectively combined with the surrounding tissue, forming good biocompatibility, degrading the connecting parts, and reducing the foreign body sensation of biological tissues.

Embodiment 6:

This embodiment is further defined on the basis of the above embodiments, the cross-section of the Morse taper foot 5 is elliptical, and the material of the Morse taper foot 5 is titanium alloy. The number of Morse taper feet 5 is four, and the four taper feet are all distributed on the periphery of the first polymethyl methacrylate layer 1, and the specific installation situation can be fixed by selecting a structurally stable area according to the actual situation, or can Avoid critical areas. The outer surface of the Morse taper foot 5 can be coated with hydroxyapatite coating to reduce foreign body properties during insertion and fixation.

Embodiment 7:

This embodiment is further defined on the basis of the above embodiments, the first insertion block 92 is a curved long plate-shaped structure, and the structure of the first insertion block 92 and the second insertion block 93 are the same. The first inserting block 92 and the second inserting block 93 are center-symmetrical to the central axis of the hydroxyapatite repair layer 1 . In this embodiment, the purpose of setting the first inserting block 92 and the second inserting block 93 is to facilitate fixing the overall structure formed by the hydroxyapatite repairing layer 91 and the titanium alloy repairing layer 97 , so as to be in good contact with the damaged tissue. In addition, in this embodiment, the shape of the first insertion block is preferably a curved long strip structure, which is beneficial to good contact between the first insertion block and the second insertion block and surrounding tissues.

The specific structure of the inner fixing piece 9, the outer fixing piece 1-1, and the connector 8 described in this embodiment can be prepared by additive manufacturing technology, and the specific aperture size and porosity can be adjusted through existing software settings. The modulus of elasticity, combined with computer-aided three-dimensional design to form a similar bionic structure, achieve mechanical properties matching with bone tissue, facilitate cross-sectional stress conduction, and increase the fixation effect of the porous bionic skull repair structure.

The specific embodiments described above have further described the purpose, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above descriptions are only specific embodiments of the present invention and are not intended to limit the scope of the present invention. Protection scope, within the spirit and principles of the present invention, any modification, equivalent replacement, improvement, etc., shall be included in the protection scope of the present invention.

Claims (10)

1. a kind of porous bionical skull based on increases material manufacturing technology repairs structure, including outer fixinig plate (1-1), interior fixinig plate (9), it is connect between outer fixinig plate (1-1) and interior fixinig plate (9) by connector (8), which is characterized in that the outer fixinig plate (1-1) include the first polymethyl methacrylate layers (1), the second polymethyl methacrylate layers (2), the first titanium alloy reticulated (3), Second titanium alloy reticulated (4), the first titanium alloy reticulated (3) are located at the upper end of the second titanium alloy reticulated (4), the first polymethyl methacrylate Layer (1) setting is arranged in the upper end of the first titanium alloy reticulated (3), the second polymethyl methacrylate layers (2) in the second titanium alloy reticulated (4) lower end, the first polymethyl methacrylate layers (1), the second polymethyl methacrylate layers (2), the first titanium alloy reticulated (3), the second titanium alloy reticulated (4) is the mesh-plate structure of arch, and the first polymethyl methacrylate layers (1) are that cross section is oval The structure of shape, the periphery of the first polymethyl methacrylate layers (1) are set there are four connecting plate (7), and four connecting plates (7) are with first The central axis of polymethyl methacrylate layers (1) is centrosymmetric for axis, and the end of four connecting plates (7) is respectively connected with Morse cone It spends foot (5)；The interior fixinig plate (9) includes hydroxyapatite repair layer (91), titanium alloy repair layer (97), and hydroxyapatite is repaired Cladding (91) is located at the upper end of titanium alloy repair layer (97), and titanium alloy repair layer (97) is equipped with reticulated cell, and hydroxyapatite is repaired Both ends in cladding (91) positioned at long axis are respectively equipped with the first inserting block (92), the second inserting block (93), and hydroxyapatite is repaired Both ends in cladding (91) positioned at short axle are respectively equipped with first through hole (94), the second through-hole (95), and first through hole (94), second are led to It is inserted into hole (95) and follows closely hydroxyapatite repair layer (91) and titanium alloy repair layer (97) fixed titanium.

2. a kind of porous bionical skull based on increases material manufacturing technology repairs structure according to claim 1, which is characterized in that Second polymethyl methacrylate layers (2), the first titanium alloy reticulated (3), the second titanium alloy reticulated (4), the first polymethyl It is parallel to each other between sour methyl esters layer (1), the crooked radian of first polymethyl methacrylate layers (1) is 30-45 °.

3. a kind of porous bionical skull based on increases material manufacturing technology according to claim 1 repairs structure, feature exists In the center angle of the extended line intersection of four connecting plates (7) is 90 °.

4. a kind of porous bionical skull based on increases material manufacturing technology according to claim 1 repairs structure, feature exists In first inserting block (92), the second inserting block (93) are to be centrosymmetric with the central axis of hydroxyapatite repair layer (1) Structure.

5. a kind of porous bionical skull based on increases material manufacturing technology according to claim 1 repairs structure, feature exists In first polymethyl methacrylate layers (1) are equipped with circular hole (11), and the aperture of circular hole (11) is 50-300um.

6. a kind of porous bionical skull based on increases material manufacturing technology according to claim 1 repairs structure, feature exists In the connector (8) includes first connecting rod (82), the second connecting rod (87), the first tapered portion (83), the second tapered portion (86), third connecting rod (84), the 4th connecting rod (85), one end and outer fixinig plate (1-1) of the first connecting rod (82) Lower surface is detachably connected, and the other end and the first tapered portion (83) of first connecting rod (82) are detachably connected, the first tapered portion It (83) be cross section is round, and round diameter successively reduces from top to bottom, the lower end of the first tapered portion (83) is connect with third Bar (84) connection.

7. a kind of porous bionical skull based on increases material manufacturing technology according to claim 6 repairs structure, feature exists In, one end of second connecting rod (87) is connect with the upper surface of interior fixinig plate (9), the other end of the second connecting rod (87) with Second tapered portion (86) connection, the structure of the second tapered portion (86) is identical as the structure of the first tapered portion (83), the first tapered portion (83) it is connect with the 4th connecting rod (85), third connecting rod (84) is detachably connected with the 4th connecting rod (85).

8. a kind of porous bionical skull based on increases material manufacturing technology according to claim 6 repairs structure, feature exists In, the third connecting rod (84) is that cross section is circular structure, and the 4th connecting rod (85) is the hollow structure of upper end opening, Third connecting rod (84) is inserted into the inside of the 4th connecting rod (85), the third connecting rod (84) and the 4th connecting rod (85) Shape adaptation, and to be threadedly coupled, the inner surface of the 4th connecting rod (85) are equipped with internal screw thread, third connecting rod (84) it is outer Surface is equipped with external screw thread, and the longitudinal length of third connecting rod (84) is less than or equal to the longitudinal length of the 4th connecting rod (85).

9. a kind of porous bionical skull based on increases material manufacturing technology according to claim 6 repairs structure, feature exists In the cross section of the Morse taper foot (5) is ellipse, and the material that the Morse taper foot (5) uses is titanium alloy.

10. a kind of porous bionical skull based on increases material manufacturing technology according to claim 1 repairs structure, feature exists In first inserting block (92) is curved long strip-board shape structure, the knot of the first inserting block (92) and the second inserting block (93) Structure is identical.