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CN108261189A - Method and device for non-invasive continuous real-time accurate measurement of arterial blood pressure - Google Patents

Method and device for non-invasive continuous real-time accurate measurement of arterial blood pressure Download PDF

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CN108261189A
CN108261189A CN201611254741.8A CN201611254741A CN108261189A CN 108261189 A CN108261189 A CN 108261189A CN 201611254741 A CN201611254741 A CN 201611254741A CN 108261189 A CN108261189 A CN 108261189A
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arterial blood
positioning sensors
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黄文霞
叶娅兰
杜磊
侯孟书
胡晓林
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West China Hospital of Sichuan University
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    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
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Abstract

本发明涉及无创连续实时准确测量动脉血压的方法及装置,该方法为:将动脉血管两侧的组织下压以凸显出动脉血管,然后将测压传感器从动脉血管上方垂直下压动脉血管至扁平态,利用测压传感器对动脉血压进行测量;该装置包括传感器组件、控制器组件和电机组,传感器组件包括测压传感器和两个定位传感器,电机组用于驱动传感器组件的移动,传感器组件将信号传递给控制器组件,控制器组件控制电机组的运转。本发明中将血管周围的肌腱等组织带动压下去,将血管从覆盖的组织中凸显出来,使血压的测量受到的干扰因素更小,减少了动脉血管内压力信号在转移过程中的损耗,使得测量结果更加准确,即使在皮肤表层能够检测到更加强烈的动脉搏动。

The present invention relates to a method and device for measuring arterial blood pressure in a non-invasive, continuous, real-time and accurate manner. The method comprises: pressing down the tissues on both sides of the arterial blood vessel to highlight the arterial blood vessel, and then vertically pressing down the arterial blood vessel from above the arterial blood vessel with a manometry sensor until flat state, using a pressure sensor to measure arterial blood pressure; the device includes a sensor assembly, a controller assembly and a motor unit, the sensor assembly includes a pressure measurement sensor and two positioning sensors, the motor unit is used to drive the movement of the sensor assembly, and the sensor assembly will The signal is transmitted to the controller component, and the controller component controls the operation of the motor unit. In the present invention, the tendons and other tissues around the blood vessels are driven down, and the blood vessels are highlighted from the covered tissues, so that the interference factors of the blood pressure measurement are smaller, and the loss of the pressure signal in the arteries during the transfer process is reduced, so that Measurements are more accurate, even stronger arterial pulses can be detected in the superficial layers of the skin.

Description

无创连续实时准确测量动脉血压的方法及装置Method and device for noninvasive, continuous, real-time and accurate measurement of arterial blood pressure

技术领域technical field

本发明涉及动脉定位与血压测量技术领域,尤其涉及无创连续实时准确测量动脉血压的方法及装置。The invention relates to the technical field of arterial positioning and blood pressure measurement, in particular to a method and device for non-invasive, continuous, real-time and accurate measurement of arterial blood pressure.

背景技术Background technique

在临床的大型手术以及ICU等紧急医用场合中,需要对患者的血压进行准确连续的每搏测量。通过对血压实时地观察,医生可以判断血液循环系统的参数,从而有针对性的进行治疗。临床上目前普遍的方法是使用连续的动脉穿刺导管方法来测量血压,该方法的测量结果是医学界关于测量血压的金标准。该方法虽然准确,但是会对人体造成损伤,而且对操作人员的要求比较高。医学界对于能够无创连续实时准确测量血压的设备有很强烈的需求,同时也一直是医疗科学研究的热门。In clinical large-scale surgery and emergency medical occasions such as ICU, accurate and continuous stroke-per-beat measurement of the patient's blood pressure is required. By observing the blood pressure in real time, doctors can judge the parameters of the blood circulation system, so as to carry out targeted treatment. The current common clinical method is to use continuous arterial puncture catheter method to measure blood pressure, and the measurement result of this method is the gold standard for measuring blood pressure in the medical field. Although this method is accurate, it will cause damage to the human body, and the requirements for operators are relatively high. The medical community has a strong demand for equipment that can measure blood pressure non-invasively, continuously and accurately in real time, and it has always been a hot spot in medical science research.

关于无创地血压测量方式,有听诊测量法、振动测量法、超声波测量法、动脉张力测量法以及恒定容积测量法。Regarding noninvasive blood pressure measurement methods, there are auscultation measurement method, vibration measurement method, ultrasonic measurement method, arterial tonometry method, and constant volume measurement method.

听诊测量法、振动测量法、超声波测量法是通过检测发生的柯式音来确定患者的心脏的收缩压和舒张压,然而这三种方法需要通过袖带轮流充气放气,都仅能间歇性地测定压力值,不能在连续时间内测得血压的收缩压和舒张压,并且不能重现患者的实际血压波形,因此连续地每搏血压测量不能通过这些方法得以实现。Auscultatory measurement, vibration measurement, and ultrasonic measurement determine the systolic and diastolic blood pressure of the patient's heart by detecting the Korotkoff sounds. To accurately measure the pressure value, the systolic and diastolic blood pressure cannot be measured in continuous time, and the actual blood pressure waveform of the patient cannot be reproduced, so continuous stroke-per-stroke blood pressure measurement cannot be realized by these methods.

张力测量法和恒定容积测量法这两种血压测量方法是无创连续实时血压测量的主要方法。由于恒定容积法血压测量的方式是通过外界施加动态压力使手指或者身体其他部位的血氧参数维持在一个平稳的范围,间接地测量该动态压力而得到的血压参数,有较大的测量误差及较高的研发难度。Two blood pressure measurement methods, tonometry and constant volume measurement, are the main methods of non-invasive continuous real-time blood pressure measurement. Since the blood pressure measurement method of the constant volume method is to maintain the blood oxygen parameters of fingers or other parts of the body in a stable range by applying dynamic pressure from the outside, the blood pressure parameters obtained by indirectly measuring the dynamic pressure have large measurement errors and High R&D difficulty.

动脉张力测量法,通过压力传感器,置于动脉之上的皮肤,根据动脉张力的理论进行测量,该方法直接根据测得的压力值进行转换而得到血压值,以这种方式进行连续性检测的血压测量方法很热门,本专利就是利用动脉张力测量法原理来实现精确测量人体的血压值。Arterial tension measurement method, through the pressure sensor, placed on the skin above the artery, measured according to the theory of arterial tension, this method directly converts the measured pressure value to obtain the blood pressure value, in this way for continuous detection The blood pressure measurement method is very popular, and this patent uses the principle of the arterial tension measurement method to realize accurate measurement of the blood pressure value of the human body.

根据张力法原理,具有充分骨骼支撑的浅层动脉(如足背动脉、桡动脉)内的压力可能在一个透壁压力为零的,即血管为压平状态时被准确的记录下来。在压平状态下,动脉血管被压成狗骨状,在此压力的作用下,通常认为得到的压力是最大的峰峰值,此时得到的压力与零透壁压力相对应,此时通过压在血管正上方皮肤表面的压力传感器得到的波形即为动态血压的波形。According to the principle of tension method, the pressure in superficial arteries with sufficient skeletal support (such as dorsalis pedis, radial artery) may be accurately recorded when the transmural pressure is zero, that is, the blood vessel is in a flattened state. In the state of applanation, the arterial vessel is compressed into a dog-bone shape. Under the action of this pressure, it is generally considered that the obtained pressure is the maximum peak-to-peak value. The obtained pressure at this time corresponds to zero transmural pressure. The waveform obtained by the pressure sensor on the skin surface just above the blood vessel is the waveform of ambulatory blood pressure.

张力测量系统,通常也对压力传感器在被测量部位上的方向比较敏感,因此需要在测量的时候,传感器要垂直压在动脉血管正中央上方。因此寻找血管的位置,并将传感器压在正确的方向和精准地压在血管上尤其重要。Tension measurement systems are usually also sensitive to the direction of the pressure sensor on the site to be measured, so the sensor needs to be pressed vertically above the center of the arterial vessel during measurement. Therefore, it is especially important to find the position of the blood vessel and press the sensor in the correct direction and precisely on the blood vessel.

动脉血管内的压力通过人体组织等传递上来,不可避免地会有转移损失。尤其在进行足背动脉血压测量的时候,由于脚动脉处的肌腱很丰富,遮挡部分血管,在测量的时候,在皮肤上感受到的血压的搏动要比压在手腕处感受到的搏动要轻微。同样在腕部桡动脉进行测量的时候,由于有较厚的脂肪层对血管的压力具有缓冲作用,体质肥胖的人往往在皮肤表层测到的脉搏相对要微弱。The pressure in the arteries is transmitted up through human tissues, and there will inevitably be transfer losses. Especially when measuring the blood pressure of the dorsalis pedis artery, because the tendons at the foot artery are very rich and cover part of the blood vessels, when measuring, the blood pressure pulsation felt on the skin is slightly lighter than the pulsation felt when pressed on the wrist . Similarly, when measuring the radial artery at the wrist, because the thicker fat layer has a buffering effect on the pressure of the blood vessel, the pulse measured on the surface of the skin of obese people is often relatively weak.

精确地定位血管并且将传感器垂直放在血管的正上方和减小组织对血管压力造成的损失对于动脉张力测量法准确测量相关动脉参数是至关重要的。关于精确定位血管位置,现有的产品基本上是通过横向和纵向地不断扫描,将传感器定位不同的位置,检测器测到的波形具有最大峰峰值的位置那就是血管的位置。关于减小由于中间组织造成的压力损失,现有的普遍做法是,在进行腕部桡动脉测量时,将腕部向外弯曲,使桡动脉从组织中暴露更多出来,从而使皮肤表层的感受到的动脉搏动更加强烈,但是长时间将手腕弯曲一定角度会使受试者或病人感到非常地不舒适。Precise positioning of the vessel and placing the sensor vertically above the vessel and reducing tissue loss of pressure on the vessel are critical for accurate measurement of relevant arterial parameters by arterial tonometry. Regarding the precise positioning of blood vessel positions, existing products basically scan horizontally and vertically to position the sensor at different positions. The position where the waveform measured by the detector has the largest peak-to-peak value is the position of the blood vessel. With regard to reducing the pressure loss due to the intermediate tissue, the existing common practice is to bend the wrist outward when taking the radial artery measurement of the wrist, so that the radial artery is exposed more from the tissue, so that the surface of the skin The perceived arterial pulse is stronger, but bending the wrist at an angle for a long time can be very uncomfortable for the subject or patient.

尤其是对于减小组织对动脉血管搏动产生的压力穿透造成的损失这方面,还未找到合适的方法,这样会使检测到的血压信号偏低,使血压的测量误差偏大。而且,上述的腕部向外弯曲也只能对部分受测者有作用。In particular, no suitable method has been found for reducing the loss caused by tissue pressure penetration caused by arterial pulsation, which will cause the detected blood pressure signal to be on the low side and cause the blood pressure measurement error to be too large. Moreover, the above-mentioned outward bending of the wrist can only have an effect on some subjects.

发明内容Contents of the invention

本发明旨在提供无创连续实时准确测量动脉血压的方法及装置,来解决精确定位动脉血管和减小组织对动脉脉搏产生的压力穿透造成的损失这两个问题。The present invention aims to provide a non-invasive, continuous, real-time and accurate method and device for measuring arterial blood pressure, so as to solve the two problems of precisely locating arterial blood vessels and reducing the loss caused by tissue pressure penetration generated by arterial pulses.

文中涉及术语“横向扫描”和“垂直扫描”,横向扫描是指压力传感器在远离人体动脉处向动脉正上方靠近,再离开动脉的过程。此处的“扫描”一般是指线性的位置变动,也可以是其他任何方式。The term "transverse scanning" and "vertical scanning" are involved in this article, and the horizontal scanning refers to the process in which the pressure sensor moves away from the human artery to directly above the artery, and then leaves the artery. The "scanning" here generally refers to linear position changes, and can also be in any other way.

垂直扫描是指压力传感器垂直于动脉血管向下施加压力的过程。在这个扫描过程中,动脉血管由不发生变化到压为扁平状态再到过度压缩状态,压力传感器再回到动脉血管被压为扁平状态时刻的位置。Vertical scanning is the process in which the pressure sensor applies downward pressure perpendicular to the arterial vessel. During this scanning process, the arterial vessel changes from no change to a flattened state and then to an over-compressed state, and the pressure sensor returns to the position at the moment when the arterial vessel is compressed into a flattened state.

为达到上述目的,本发明采用的技术方案如下:In order to achieve the above object, the technical scheme adopted in the present invention is as follows:

通过精确及可重复(视需要)地在被测个体的生理组织上配置传感器组件,传感器组件包含至少三个或更多压力传感器,其中至少一个是用于测量受试者血压或其它参数的传感器,把它称作测压传感器;其中另两个压力传感器是用来精确定位动脉血管,把它们称作定位传感器。By accurately and repeatably (if necessary) disposing the sensor assembly on the physiological tissue of the individual to be measured, the sensor assembly includes at least three or more pressure sensors, at least one of which is a sensor for measuring the subject's blood pressure or other parameters , which is called a pressure sensor; the other two pressure sensors are used to accurately locate the arterial blood vessels, and they are called positioning sensors.

无创连续实时准确测量动脉血压的方法,将动脉血管两侧的组织下压以凸显出动脉血管,然后将测压传感器从动脉血管上方垂直下压动脉血管至扁平态,利用测压传感器对动脉血压进行测量。血管扁平态时动脉透壁压力为零,此时动脉血管被压成狗骨状,此时通过压在血管正上方皮肤表面的压力传感器得到的波形即为动态血压的波形。具体包括以下步骤:Non-invasive, continuous, real-time and accurate measurement of arterial blood pressure. The tissue on both sides of the arterial vessel is pressed down to highlight the arterial vessel, and then the manometry sensor is vertically pressed down the arterial vessel from above the arterial vessel to a flat state, and the arterial blood pressure is measured using the manometry sensor. Take measurements. When the blood vessel is flat, the arterial transmural pressure is zero. At this time, the arterial blood vessel is compressed into a dog-bone shape. At this time, the waveform obtained by the pressure sensor pressed on the skin surface directly above the blood vessel is the waveform of ambulatory blood pressure. Specifically include the following steps:

步骤1、确定动脉位置,所述步骤1包括以下步骤:Step 1, determining the position of the artery, said step 1 comprises the following steps:

子步骤1.1、用传感器组件横向扫描患者皮肤,记录扫描过程中定位传感器采集的脉压和该脉压对应的位置,所述传感器组件包括两个横向并排设置的定位传感器;Sub-step 1.1, scan the patient's skin laterally with the sensor assembly, record the pulse pressure collected by the positioning sensor and the position corresponding to the pulse pressure during the scanning process, the sensor assembly includes two positioning sensors arranged side by side laterally;

子步骤1.2、停止扫描,检索出两个定位传感器采集的脉压和的最大值及该最大值对应的位置;Sub-step 1.2, stop scanning, retrieve the maximum value of the pulse pressure sum collected by the two positioning sensors and the position corresponding to the maximum value;

子步骤1.3、横向移动传感器组件至所述最大值对应的位置;Sub-step 1.3, laterally moving the sensor assembly to the position corresponding to the maximum value;

步骤2、凸显动脉血管,所述步骤2包括以下步骤:Step 2, highlighting arterial vessels, said step 2 includes the following steps:

子步骤2.1、分别横向移动两个定位传感器,当定位传感器采集的脉压为0时停止移动,两个定位传感器的移动方向相反;Sub-step 2.1, move the two positioning sensors laterally respectively, and stop moving when the pulse pressure collected by the positioning sensors is 0, and the moving directions of the two positioning sensors are opposite;

子步骤2.2、使两个定位传感器垂直向下移动一定距离,将动脉血管从覆盖的组织中凸显出来;下压距离可以根据本领域技术人员的经验来设置,此处不再赘述。Sub-step 2.2, move the two positioning sensors vertically downward for a certain distance to highlight the arterial vessel from the covered tissue; the pressing distance can be set according to the experience of those skilled in the art, and will not be repeated here.

步骤3、测量动脉血压,所述步骤3包括以下步骤:Step 3, measure arterial blood pressure, described step 3 comprises the following steps:

子步骤3.1、使测压传感器在两个定位传感器之间作垂直扫描,记录扫描过程中测压传感器采集的脉压和该脉压对应的位置信息;Sub-step 3.1, make the pressure measuring sensor perform vertical scanning between the two positioning sensors, record the pulse pressure collected by the pressure measuring sensor and the position information corresponding to the pulse pressure during the scanning process;

子步骤3.2、停止扫描,检索出测压传感器采集的脉压的最大值及该最大值对应的位置;Sub-step 3.2, stop scanning, and retrieve the maximum value of the pulse pressure collected by the pressure sensor and the position corresponding to the maximum value;

子步骤3.3、垂直移动测压传感器到所述脉压最大值对应的位置,利用测压传感器对动脉血压进行测量。Sub-step 3.3, vertically move the manometry sensor to the position corresponding to the maximum pulse pressure, and use the manometry sensor to measure the arterial blood pressure.

进一步的,所述步骤1之前复位所述传感器组件;复位状态时,两个定位传感器相接触,测压传感器位于定位两个定位传感器正上方。Further, the sensor assembly is reset before step 1; in the reset state, the two positioning sensors are in contact, and the load cell is located directly above the two positioning sensors.

进一步的,上述方法是利用无创连续实时准确测量动脉血压的装置来处理的,所述装置包括传感器组件、控制器组件和电机组,所述传感器组件包括测压传感器和两个定位传感器,所述电机组用于驱动传感器组件的横向移动和垂直移动,所述传感器组件将信号传递给控制器组件,所述控制器组件控制电机组的运转。Further, the above method is processed by using a device for non-invasive continuous real-time accurate measurement of arterial blood pressure, the device includes a sensor assembly, a controller assembly and a motor unit, the sensor assembly includes a pressure sensor and two positioning sensors, the The motor set is used to drive the sensor assembly to move laterally and vertically, and the sensor assembly transmits signals to the controller assembly, and the controller assembly controls the operation of the motor set.

进一步的,所述控制器组件的信号采集频率为50Hz。Further, the signal acquisition frequency of the controller component is 50 Hz.

进一步的,每个定位传感器的移动分别由两个电机驱动,测压传感器的移动分别由两个电机驱动,所述控制器组件控制每个电机的运转。当然的,也可以只用5个电机,其中3个电机分别控制3个传感器的横向移动;另1个电机控制测压传感器的垂直移动,另1个电机控制两个定位传感器的垂直移动。Further, the movement of each positioning sensor is respectively driven by two motors, the movement of the load cell is respectively driven by two motors, and the controller component controls the operation of each motor. Of course, only 5 motors can be used, 3 of which control the lateral movement of the 3 sensors respectively; the other 1 motor controls the vertical movement of the load cell, and the other 1 motor controls the vertical movement of the two positioning sensors.

无创连续实时准确测量动脉血压的装置,包括传感器组件、控制器组件和电机组,所述传感器组件包括测压传感器和两个定位传感器,所述电机组用于驱动传感器组件的横向移动和垂直移动,所述传感器组件将信号传递给控制器组件,所述控制器组件控制电机组的运转。A device for non-invasive, continuous, real-time and accurate measurement of arterial blood pressure, comprising a sensor assembly, a controller assembly, and a motor set, the sensor assembly includes a manometric sensor and two positioning sensors, and the motor set is used to drive the sensor assembly to move laterally and vertically , the sensor component transmits the signal to the controller component, and the controller component controls the operation of the motor unit.

作为优选,所述两个定位传感器平行并排在同一的水平面上,两个定位传感器相接触,所述测压传感器位于两个定位传感器正上方。Preferably, the two positioning sensors are parallel and arranged on the same horizontal plane, the two positioning sensors are in contact, and the load cell is located directly above the two positioning sensors.

进一步的,还包括测量装置本体和设置在测量装置本体上的固定带,所述传感器组件、控制器组件和电机组设于测量装置本体中。Further, it also includes a measuring device body and a fixing belt arranged on the measuring device body, and the sensor assembly, the controller assembly and the motor assembly are arranged in the measuring device body.

进一步的,所述测量装置本体设有测量腔室,所述测量腔室底部敞口,所述传感器组件位于测量腔室中。Further, the measuring device body is provided with a measuring chamber, the bottom of which is open, and the sensor assembly is located in the measuring chamber.

进一步的,所述控制器组件和电机组位于传感器组件上方。Further, the controller assembly and the motor assembly are located above the sensor assembly.

进一步的,所述电机组包括六个电机,所述测压传感器的横向移动和垂直移动分别由两个电机控制,所述定位传感器的横向移动和垂直移动分别由两个电机控制,所述定位传感器的横向移动和垂直移动分别由两个电机控制。Further, the motor group includes six motors, the lateral movement and vertical movement of the load cell are respectively controlled by two motors, the lateral movement and vertical movement of the positioning sensor are respectively controlled by two motors, and the positioning The lateral movement and vertical movement of the sensor are respectively controlled by two motors.

与现有技术相比,本发明具有以下有益效果:Compared with the prior art, the present invention has the following beneficial effects:

本发明可精确的定位动脉血管的位置,定位传感器的下压,可以将血管周围的肌腱等组织带动压下去,将血管尽可能的从覆盖的组织中凸显出来,从而使皮肤表层能够检测到更加强烈的动脉搏动。在张力测量法的应用上,本发明可以使血压的测量受到的干扰因素更小,并且,减少了动脉血管内压力信号在转移过程中的损耗,使得测量结果更加准确,即使在脉搏相对微弱的足背动脉处,也有很好的测量结果。The present invention can accurately locate the position of the arterial blood vessel, and the downward pressure of the positioning sensor can drive down the tendon and other tissues around the blood vessel, so that the blood vessel can be highlighted from the covered tissue as much as possible, so that the surface layer of the skin can be detected more Strong arterial pulses. In the application of tonometry, the present invention can make the measurement of blood pressure less disturbed, and reduce the loss of the pressure signal in the arterial vessel during the transfer process, making the measurement result more accurate, even when the pulse is relatively weak There are also good measurements at the dorsalis pedis artery.

附图说明Description of drawings

图1是本发明中方法的流程图;Fig. 1 is the flowchart of method among the present invention;

图2是本发明中装置的结构示意图;Fig. 2 is the structural representation of device among the present invention;

图3是本发明中装置佩戴在脚上的结构示意图;Fig. 3 is a structural schematic diagram of the device worn on the foot in the present invention;

图4是本发明中传感器组件的结构示意图;Fig. 4 is the structural representation of sensor assembly among the present invention;

图中:101-右脚、102-足背动脉、200-测量装置本体、201-固定带、202-固定支架、203-传感器组件、204-电机组、205-控制器组件、206-测量腔室、232-第一定位传感器、233-第二定位传感器。In the figure: 101-right foot, 102-dorsalis pedis artery, 200-measuring device body, 201-fixing belt, 202-fixing bracket, 203-sensor component, 204-motor unit, 205-controller component, 206-measurement cavity Chamber, 232 - first positioning sensor, 233 - second positioning sensor.

具体实施方式Detailed ways

为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图,对本发明进行进一步详细说明。In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings.

需要注意的是,本具体实施方式中主要描述了在人体的脚背处精确寻找足背动脉的方法和装置,但是本发明也同样适用于人体其他部位寻找动脉血管,比如精确定位桡动脉、肱动脉、股动脉、颈动脉等。It should be noted that this specific embodiment mainly describes the method and device for accurately finding the dorsalis pedis artery at the instep of the human body, but the present invention is also applicable to finding arteries in other parts of the human body, such as accurately locating the radial artery and the brachial artery. , femoral artery, carotid artery, etc.

如图1所示,本发明公开的无创连续实时准确测量动脉血压的方法,将动脉血管两侧的组织下压以凸显出动脉血管,然后将测压传感器从动脉血管上方垂直下压动脉血管至扁平态,利用测压传感器对动脉血压进行测量。具体包括以下步骤:As shown in Figure 1, the non-invasive, continuous, real-time and accurate method for measuring arterial blood pressure disclosed by the present invention, presses down the tissues on both sides of the arterial blood vessel to highlight the arterial blood vessel, and then presses the manometry sensor vertically from above the arterial blood vessel to the arterial blood vessel. In a flat state, the arterial blood pressure is measured using a manometry sensor. Specifically include the following steps:

步骤1、确定动脉位置,所述步骤1包括以下步骤:Step 1, determining the position of the artery, said step 1 comprises the following steps:

子步骤1.1、用传感器组件横向扫描患者皮肤,记录扫描过程中定位传感器采集的脉压和该脉压对应的位置,所述传感器组件包括两个横向并排设置的定位传感器;Sub-step 1.1, scan the patient's skin laterally with the sensor assembly, record the pulse pressure collected by the positioning sensor and the position corresponding to the pulse pressure during the scanning process, the sensor assembly includes two positioning sensors arranged side by side laterally;

子步骤1.2、停止扫描,检索出两个定位传感器采集的脉压和的最大值及该最大值对应的位置;Sub-step 1.2, stop scanning, retrieve the maximum value of the pulse pressure sum collected by the two positioning sensors and the position corresponding to the maximum value;

子步骤1.3、横向移动传感器组件至所述最大值对应的位置;使传感器组件的中线对齐所述最大值对应的位置,两个定位传感器关于中线对称设置。Sub-step 1.3, move the sensor assembly laterally to the position corresponding to the maximum value; align the midline of the sensor assembly with the position corresponding to the maximum value, and set the two positioning sensors symmetrically about the midline.

步骤2、凸显动脉血管,所述步骤2包括以下步骤:Step 2, highlighting arterial vessels, said step 2 includes the following steps:

子步骤2.1、分别横向移动两个定位传感器,当定位传感器采集的脉压为0时停止移动,即两个定位传感器感受不到脉搏搏动的压力信号时停止;两个定位传感器的移动方向相反;Sub-step 2.1, move the two positioning sensors laterally respectively, and stop moving when the pulse pressure collected by the positioning sensors is 0, that is, stop when the two positioning sensors do not feel the pulse pressure signal; the moving directions of the two positioning sensors are opposite;

子步骤2.2、使两个定位传感器垂直向下移动一定距离,将动脉血管从覆盖的组织中凸显出来;下压距离可以根据本领域技术人员的经验来设置,此处不再赘述。Sub-step 2.2, move the two positioning sensors vertically downward for a certain distance to highlight the arterial vessel from the covered tissue; the pressing distance can be set according to the experience of those skilled in the art, and will not be repeated here.

步骤3、测量动脉血压,所述步骤3包括以下步骤:Step 3, measure arterial blood pressure, described step 3 comprises the following steps:

子步骤3.1、使测压传感器在两个定位传感器之间作垂直扫描,记录扫描过程中测压传感器采集的脉压和该脉压对应的位置信息;Sub-step 3.1, make the pressure measuring sensor perform vertical scanning between the two positioning sensors, record the pulse pressure collected by the pressure measuring sensor and the position information corresponding to the pulse pressure during the scanning process;

子步骤3.2、停止扫描,检索出测压传感器采集的脉压的最大值及该最大值对应的位置;Sub-step 3.2, stop scanning, and retrieve the maximum value of the pulse pressure collected by the pressure sensor and the position corresponding to the maximum value;

子步骤3.3、垂直移动测压传感器到所述脉压最大值对应的位置,利用测压传感器对动脉血压进行测量。Sub-step 3.3, vertically move the manometry sensor to the position corresponding to the maximum pulse pressure, and use the manometry sensor to measure the arterial blood pressure.

进一步的,所述步骤1之前复位所述传感器组件;复位状态时,两个定位传感器相接触,测压传感器位于定位两个定位传感器正上方。本发明方法是利用无创连续实时准确测量动脉血压的装置来处理的,Further, the sensor assembly is reset before step 1; in the reset state, the two positioning sensors are in contact, and the load cell is located directly above the two positioning sensors. The method of the present invention utilizes a non-invasive, continuous, real-time and accurate device for measuring arterial blood pressure.

如图2、3所示,本发明公开的无创连续实时准确测量动脉血压的装置,包括传感器组件203、控制器组件205和电机组204,传感器组件203包括测压传感器231、第一定位传感器232和第二定位传感器233,电机组204用于驱动传感器组件203的横向移动和垂直移动,传感器组件203将信号传递给控制器组件205,控制器组件205控制电机组204的运转。其中控制器组件205每秒采集50个,即信号采集频率为50Hz。作为优选,两个定位传感器为大小相同、材料相同的长条形压力传感器,测压传感器为一个直径大小为2至6mm的压力传感器。如图4所示,第一定位传感器232和第二定位传感器233的横截面为矩形,测压传感器231为圆柱形,测压传感器231的轴线垂直于第一定位传感器232和第二定位传感器233。As shown in Figures 2 and 3, the device for non-invasive continuous real-time and accurate measurement of arterial blood pressure disclosed by the present invention includes a sensor assembly 203, a controller assembly 205, and a motor unit 204, and the sensor assembly 203 includes a pressure measuring sensor 231 and a first positioning sensor 232 and the second positioning sensor 233 , the motor unit 204 is used to drive the sensor unit 203 to move laterally and vertically, the sensor unit 203 transmits a signal to the controller unit 205 , and the controller unit 205 controls the operation of the motor unit 204 . The controller component 205 collects 50 signals per second, that is, the signal collection frequency is 50 Hz. Preferably, the two positioning sensors are elongated pressure sensors with the same size and material, and the pressure sensor is a pressure sensor with a diameter of 2 to 6 mm. As shown in Figure 4, the cross section of the first positioning sensor 232 and the second positioning sensor 233 is rectangular, the load cell 231 is cylindrical, and the axis of the load cell 231 is perpendicular to the first positioning sensor 232 and the second positioning sensor 233 .

每个定位传感器的移动分别由两个电机驱动,测压传感器的移动分别由两个电机驱动,进一步的,电机组204包括六个电机,测压传感器231的横向移动和垂直移动分别由两个电机控制,第一定位传感器232的横向移动和垂直移动分别由两个电机控制,第二定位传感器233的横向移动和垂直移动分别由两个电机控制。The movement of each positioning sensor is driven by two motors respectively, and the movement of the pressure measuring sensor is driven by two motors respectively. Further, the motor group 204 includes six motors, and the lateral movement and vertical movement of the pressure measuring sensor 231 are respectively driven by two motors. Motor control, the lateral movement and vertical movement of the first positioning sensor 232 are respectively controlled by two motors, and the lateral movement and vertical movement of the second positioning sensor 233 are respectively controlled by two motors.

进一步的,还包括测量装置本体200、设置在测量装置本体200上的固定带201,测量装置本体200两侧设有固定支架202,固定带201与固定支架202连接。传感器组件203、控制器组件205和电机组204设于测量装置本体200中。测量装置本体200设有测量腔室206,测量腔室206底部敞口,传感器组件203位于测量腔室206中,其中,两个定位传感器的底面与测量腔室206底面齐平。控制器组件205和电机组204位于传感器组件203上方。固定带201和固定支架202主要用来把装置稳稳地固定在脚背上,确保在小的干扰下也能准确测量受试者的血压和其他参数。Further, it also includes a measuring device body 200 and a fixing belt 201 arranged on the measuring device body 200 , and fixing brackets 202 are arranged on both sides of the measuring device body 200 , and the fixing belt 201 is connected to the fixing bracket 202 . The sensor assembly 203 , the controller assembly 205 and the motor assembly 204 are arranged in the measuring device body 200 . The measurement device body 200 is provided with a measurement chamber 206 , the bottom of which is open, and the sensor assembly 203 is located in the measurement chamber 206 , wherein the bottom surfaces of the two positioning sensors are flush with the bottom surface of the measurement chamber 206 . Controller assembly 205 and motor pack 204 are located above sensor assembly 203 . The fixing belt 201 and the fixing bracket 202 are mainly used to firmly fix the device on the instep, so as to ensure that the blood pressure and other parameters of the subject can be accurately measured even with little interference.

控制器组件205是整个测量装置的核心,起到控制作用,包含MCU等各种控制芯片及其电路。控制器组件用于和上位机的通信、信号检测和逻辑处理及控制电机。本具体实施方式中控制器组件采用MCU系统,但不局限于MCU,根据不同场合需要,可以是DSP、CPLD和FPGA等嵌入式芯片。控制器组件会通过接口读取传感器组件所测得的实时数据,以及发出控制信号控制制动器组件中的电机的运转。本发明中条件判断以及相应的动作执行的逻辑都该组件进行,具体的实现由开发人员编写程序烧录到MCU。The controller component 205 is the core of the entire measurement device, plays a control role, and includes various control chips such as MCU and their circuits. The controller component is used for communication with the upper computer, signal detection and logic processing, and motor control. In this specific embodiment, the controller component adopts the MCU system, but is not limited to the MCU, and can be embedded chips such as DSP, CPLD, and FPGA according to the needs of different occasions. The controller component reads the real-time data measured by the sensor component through the interface, and sends a control signal to control the operation of the motor in the brake component. In the present invention, the logic of condition judgment and corresponding action execution is carried out by this component, and the specific implementation is written by the developer and burnt into the MCU.

检测开始之前,将本发明装置置于要测的动脉血管附近合适位置如果传感器检测不到信号,可以适当调整佩戴位置,复位系统设置,复位电机转态,复位传感器的位置。复位的状态的时候,如图4所示,第一定位传感器232和第二定位传感器233平行并排贴在一起,且位于测量装置本体200的左侧;测压传感器231位于两个定位传感器上方的正中央。Before the detection starts, place the device of the present invention at a suitable position near the arterial vessel to be measured. If the sensor cannot detect a signal, you can properly adjust the wearing position, reset the system settings, reset the motor rotation state, and reset the position of the sensor. In the reset state, as shown in FIG. 4 , the first positioning sensor 232 and the second positioning sensor 233 are pasted together side by side in parallel, and are located on the left side of the measuring device body 200; the load cell 231 is located on the top of the two positioning sensors. right in the middle.

装置启动,在控制器组件205的控制下电机带动传感器组件进行整体横向移动来回扫描一个回合。在扫描过程中,控制器组件205从两个定位传感器以一定的频率分别读取检测到的脉压数据,将两个定位传感器脉压的和值以及此时的位置记录,作为优选频率为50HZ。The device is started, and under the control of the controller assembly 205, the motor drives the sensor assembly to move laterally as a whole and scan back and forth for one round. During the scanning process, the controller component 205 reads the detected pulse pressure data from the two positioning sensors at a certain frequency, records the sum of the pulse pressure of the two positioning sensors and the position at this time, and the preferred frequency is 50HZ .

扫描结束之后,检索出两个定位传感器的脉压和值为最大的值以及对应的位置。控制器组件205控制电机组204去带动传感器组件203,将两个闭合在一起的定位传感器的中央对应到上述和值最大值所对应位置上。After the scan ends, the pulse pressure sum value of the two positioning sensors is the largest and the corresponding position is retrieved. The controller component 205 controls the motor unit 204 to drive the sensor component 203, and the center of the two closed positioning sensors corresponds to the position corresponding to the above-mentioned maximum sum value.

使第一定位传感器232逐渐向外移动,控制器组件205检测第一定位传感器232的信号为零,停止向外移动。第二定位传感器233执行相同的操作。需要注意的是,此时定位传感器上方的测压传感器231保持原有位置不动,此刻两个定位传感器中间就是足背动脉。The first positioning sensor 232 is gradually moved outward, the controller assembly 205 detects that the signal of the first positioning sensor 232 is zero, and stops the outward movement. The second positioning sensor 233 performs the same operation. It should be noted that at this time, the pressure measuring sensor 231 above the positioning sensor remains in its original position, and the dorsalis pedis artery is between the two positioning sensors at this moment.

紧接着电机控制两个定位传感器垂直往下压,下压到中间的足背动脉有明显凸出时停止。这个明显凸出时可以通过下压距离来控制,下压距离可以根据本领域技术人员的经验来设置,此处不再赘述。Immediately afterwards, the motor controls the two positioning sensors to press down vertically, and stops when the dorsalis pedis artery in the middle is obviously protruded. When this protrusion is obvious, it can be controlled by the pressing distance, which can be set according to the experience of those skilled in the art, and will not be repeated here.

固定好定位传感器后,测压传感器231还在足背动脉正上方,控制器组件205输出控制信号控制电机组中相应的电机来驱动测压传感器231垂直扫描一个回合。记录扫描过程中的测压传感器231检测的最大值以及对应的位置,然后将测压传感器231垂直往下压到最大值对应的位置,此时动脉血管被压为扁平状态,再测压传感器231测量受试者血压及其他参数。After the positioning sensor is fixed, the pressure sensor 231 is still directly above the dorsalis pedis artery, and the controller component 205 outputs a control signal to control the corresponding motor in the motor unit to drive the pressure sensor 231 to scan vertically for one round. Record the maximum value detected by the pressure sensor 231 and the corresponding position during the scanning process, and then press the pressure sensor 231 vertically down to the position corresponding to the maximum value. Measure the subject's blood pressure and other parameters.

在精确寻找足背动脉时,控制器组件205输出控制信号给电机组204,电机组204中相应的电机接收到控制信号后开始运转,驱动第一定位传感器232和第二定位传感器233横向扫描寻找两个传感器检测的脉压值之和最大的位置,然后再控制第一定位传感器232和第二定位传感器233垂直下压,让中间的足背动脉102凸显出来。固定好定位传感器后,测压传感器231还在足背动脉正上方,驱动测压传感器231把足背动脉102压为扁平状态,测压传感器231开始测量受试者血压及其他参数。本发明可以精确的定位动脉血管的位置,定位传感的往下压,可以将血管周围的肌腱等组织带动压下去,将血管尽可能的从覆盖的组织中凸显出来,从而使皮肤表层能够检测到更加强烈的动脉搏动。在张力测量法的应用上,本发明可以使血压的测量受到的干扰因素更小,并且,减少了动脉血管内压力信号在转移过程中的损耗,使得测量结果更加准确。即使在脉搏相对微弱的足背动脉处,也有很好的测量结果。When accurately looking for the dorsalis pedis artery, the controller component 205 outputs a control signal to the motor group 204, and the corresponding motor in the motor group 204 starts to run after receiving the control signal, and drives the first positioning sensor 232 and the second positioning sensor 233 to scan horizontally to find Then control the first positioning sensor 232 and the second positioning sensor 233 to press down vertically at the position where the sum of the pulse pressure values detected by the two sensors is the largest, so that the dorsalis pedis artery 102 in the middle is highlighted. After the positioning sensor is fixed, the manometry sensor 231 is still directly above the dorsalis pedis artery, and the manometry sensor 231 is driven to press the dorsalis pedis artery 102 into a flat state, and the manometry sensor 231 starts to measure the subject's blood pressure and other parameters. The present invention can accurately locate the position of the arterial blood vessel, press down the positioning sensor, and can push down the tendon and other tissues around the blood vessel, so that the blood vessel can be highlighted from the covered tissue as much as possible, so that the surface layer of the skin can be detected to a stronger arterial pulse. In the application of the tension measurement method, the present invention can make the measurement of the blood pressure less disturbed, and reduce the loss of the pressure signal in the arterial blood vessel during the transfer process, so that the measurement result is more accurate. Good measurements even at the dorsalis pedis artery, where the pulse is relatively weak.

当然,本发明还可有其它多种实施方式,在不背离本发明精神及其实质的情况下,熟悉本领域的技术人员可根据本发明作出各种相应的改变和变形,但这些相应的改变和变形都应属于本发明所附的权利要求的保护范围。Certainly, the present invention also can have other multiple implementation modes, without departing from the spirit and essence of the present invention, those skilled in the art can make various corresponding changes and deformations according to the present invention, but these corresponding changes All changes and modifications should belong to the scope of protection of the appended claims of the present invention.

Claims (10)

1.无创连续实时准确测量动脉血压的方法,其特征在于:将动脉血管两侧的组织下压以凸显出动脉血管,然后将测压传感器从动脉血管上方垂直下压动脉血管至扁平态,利用测压传感器对动脉血压进行测量。1. The method for non-invasive continuous real-time accurate measurement of arterial blood pressure is characterized in that: the tissue on both sides of the arterial blood vessel is pressed down to highlight the arterial blood vessel, and then the manometry sensor is vertically pressed down the arterial blood vessel from above the arterial blood vessel to a flat state, using The manometry transducer measures arterial blood pressure. 2.根据权利要求1所述的方法,其特征在于:包括以下步骤:2. The method according to claim 1, characterized in that: comprising the following steps: 步骤1、确定动脉位置,所述步骤1包括以下步骤:Step 1, determining the position of the artery, said step 1 comprises the following steps: 子步骤1.1、用传感器组件横向扫描患者皮肤,记录扫描过程中定位传感器采集的脉压和该脉压对应的位置,所述传感器组件包括两个横向并排设置的定位传感器;Sub-step 1.1, scan the patient's skin laterally with the sensor assembly, record the pulse pressure collected by the positioning sensor and the position corresponding to the pulse pressure during the scanning process, the sensor assembly includes two positioning sensors arranged side by side laterally; 子步骤1.2、停止扫描,检索出两个定位传感器采集的脉压和的最大值及该最大值对应的位置;Sub-step 1.2, stop scanning, retrieve the maximum value of the pulse pressure sum collected by the two positioning sensors and the position corresponding to the maximum value; 子步骤1.3、横向移动传感器组件至所述最大值对应的位置;Sub-step 1.3, laterally moving the sensor assembly to the position corresponding to the maximum value; 步骤2、凸显动脉血管,所述步骤2包括以下步骤:Step 2, highlighting arterial vessels, said step 2 includes the following steps: 子步骤2.1、分别横向移动两个定位传感器,当定位传感器采集的脉压为0时停止移动,两个定位传感器的移动方向相反;Sub-step 2.1, move the two positioning sensors laterally respectively, and stop moving when the pulse pressure collected by the positioning sensors is 0, and the moving directions of the two positioning sensors are opposite; 子步骤2.2、使两个定位传感器垂直向下移动一定距离,将动脉血管从覆盖的组织中凸显出来;Sub-step 2.2, moving the two positioning sensors vertically downward for a certain distance to highlight the arteries from the covered tissue; 步骤3、测量动脉血压,所述步骤3包括以下步骤:Step 3, measure arterial blood pressure, described step 3 comprises the following steps: 子步骤3.1、使测压传感器在两个定位传感器之间作垂直扫描,记录扫描过程中测压传感器采集的脉压和该脉压对应的位置信息;Sub-step 3.1, make the pressure measuring sensor perform vertical scanning between the two positioning sensors, record the pulse pressure collected by the pressure measuring sensor and the position information corresponding to the pulse pressure during the scanning process; 子步骤3.2、停止扫描,检索出测压传感器采集的脉压的最大值及该最大值对应的位置;Sub-step 3.2, stop scanning, retrieve the maximum value of the pulse pressure collected by the pressure sensor and the position corresponding to the maximum value; 子步骤3.3、垂直移动测压传感器到所述脉压最大值对应的位置,利用测压传感器对动脉血压进行测量。Sub-step 3.3, vertically move the manometry sensor to the position corresponding to the maximum pulse pressure, and use the manometry sensor to measure the arterial blood pressure. 3.根据权利要求2所述的方法,其特征在于:所述步骤1之前复位所述传感器组件;复位状态时,两个定位传感器相接触,测压传感器位于定位两个定位传感器正上方。3. The method according to claim 2, wherein the sensor assembly is reset before step 1; in the reset state, the two positioning sensors are in contact, and the pressure sensor is located directly above the two positioning sensors. 4.根据权利要求2或3所述的方法,其特征在于:是利用无创连续实时准确测量动脉血压的装置来处理的,所述装置包括传感器组件、控制器组件和电机组,所述传感器组件包括测压传感器和两个定位传感器,所述电机组用于驱动传感器组件的横向移动和垂直移动,所述传感器组件将信号传递给控制器组件,所述控制器组件控制电机组的运转。4. The method according to claim 2 or 3, characterized in that: it is processed by a device for non-invasive, continuous and real-time accurate measurement of arterial blood pressure, said device comprising a sensor assembly, a controller assembly and a motor unit, said sensor assembly It includes a pressure measuring sensor and two positioning sensors. The motor unit is used to drive the sensor unit to move laterally and vertically. The sensor unit transmits signals to the controller unit, and the controller unit controls the operation of the motor unit. 5.根据权利要求4所述的方法,其特征在于:所述控制器组件的信号采集频率为50Hz。5. The method according to claim 4, characterized in that: the signal acquisition frequency of the controller component is 50 Hz. 6.无创连续实时准确测量动脉血压的装置,其特征在于:包括传感器组件、控制器组件和电机组,所述传感器组件包括测压传感器和两个定位传感器,所述电机组用于驱动传感器组件的横向移动和垂直移动,所述传感器组件将信号传递给控制器组件,所述控制器组件控制电机组的运转。6. the device of non-invasive continuous real-time accurate measurement of arterial blood pressure, it is characterized in that: comprise sensor assembly, controller assembly and motor set, described sensor assembly comprises pressure measuring sensor and two positioning sensors, and described motor set is used to drive sensor assembly The sensor assembly transmits signals to the controller assembly, and the controller assembly controls the operation of the motor unit. 7.根据权利要求6所述的装置,其特征在于:所述两个定位传感器平行并排在同一水平面上,两个定位传感器相接触,所述测压传感器位于两个定位传感器正上方。7. The device according to claim 6, wherein the two positioning sensors are parallel and arranged on the same horizontal plane, the two positioning sensors are in contact, and the pressure measuring sensor is located directly above the two positioning sensors. 8.根据权利要求6所述的装置,其特征在于:还包括测量装置本体和设置在测量装置本体上的固定带,所述传感器组件、控制器组件和电机组设于测量装置本体中。8. The device according to claim 6, characterized in that it further comprises a measuring device body and a fixing belt arranged on the measuring device body, the sensor assembly, the controller assembly and the motor unit are arranged in the measuring device body. 9.根据权利要8所述的装置,其特征在于:所述测量装置本体设有测量腔室,所述测量腔室底部敞口,所述传感器组件位于测量腔室中。9. The device according to claim 8, wherein the measuring device body is provided with a measuring chamber, the bottom of which is open, and the sensor assembly is located in the measuring chamber. 10.根据权利要9所述的装置,其特征在于:所述控制器组件和电机组位于传感器组件上方。10. The apparatus of claim 9, wherein the controller assembly and motor assembly are located above the sensor assembly.
CN201611254741.8A 2016-12-30 2016-12-30 Method and device for non-invasive continuous real-time accurate measurement of arterial blood pressure Pending CN108261189A (en)

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