CN108210401A - A kind of sun-proof synergistic compound and preparation method thereof - Google Patents
A kind of sun-proof synergistic compound and preparation method thereof Download PDFInfo
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- 230000002195 synergetic effect Effects 0.000 title claims abstract description 30
- 150000001875 compounds Chemical class 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 239000000516 sunscreening agent Substances 0.000 claims abstract description 16
- 244000037433 Pongamia pinnata Species 0.000 claims abstract description 13
- 235000004599 Pongamia pinnata Nutrition 0.000 claims abstract description 13
- 239000001421 krameria triandra root extract Substances 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 238000003756 stirring Methods 0.000 claims description 10
- 230000000475 sunscreen effect Effects 0.000 claims description 9
- 150000004676 glycans Chemical class 0.000 claims description 8
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 7
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 7
- ASWBNKHCZGQVJV-UHFFFAOYSA-N (3-hexadecanoyloxy-2-hydroxypropyl) 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)COP([O-])(=O)OCC[N+](C)(C)C ASWBNKHCZGQVJV-UHFFFAOYSA-N 0.000 claims description 7
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 claims description 7
- 102000004190 Enzymes Human genes 0.000 claims description 7
- 108090000790 Enzymes Proteins 0.000 claims description 7
- 229920002305 Schizophyllan Polymers 0.000 claims description 7
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 7
- 229940036350 bisabolol Drugs 0.000 claims description 7
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 7
- 230000034303 cell budding Effects 0.000 claims description 7
- 229920001282 polysaccharide Polymers 0.000 claims description 7
- 239000005017 polysaccharide Substances 0.000 claims description 7
- 229920001285 xanthan gum Polymers 0.000 claims description 7
- 239000001243 zingiber officinale rosc. root absolute Substances 0.000 claims description 7
- 241000628997 Flos Species 0.000 claims description 6
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- 241001156382 Lansium Species 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 4
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- 239000000654 additive Substances 0.000 abstract description 3
- 230000000996 additive effect Effects 0.000 abstract description 3
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 description 9
- WSSJONWNBBTCMG-UHFFFAOYSA-N 2-hydroxybenzoic acid (3,3,5-trimethylcyclohexyl) ester Chemical compound C1C(C)(C)CC(C)CC1OC(=O)C1=CC=CC=C1O WSSJONWNBBTCMG-UHFFFAOYSA-N 0.000 description 4
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 description 4
- KGNFCMBVSSCAGC-UHFFFAOYSA-N C(=O)OC(C1=CC=CC=C1)=O.C(C)N(OC1=CC=CC=C1)CC Chemical compound C(=O)OC(C1=CC=CC=C1)=O.C(C)N(OC1=CC=CC=C1)CC KGNFCMBVSSCAGC-UHFFFAOYSA-N 0.000 description 4
- 206010015150 Erythema Diseases 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- 125000003647 acryloyl group Chemical group O=C([*])C([H])=C([H])[H] 0.000 description 4
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 description 4
- 229920001577 copolymer Polymers 0.000 description 4
- 231100000321 erythema Toxicity 0.000 description 4
- 150000002148 esters Chemical class 0.000 description 4
- 229960004881 homosalate Drugs 0.000 description 4
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229940104261 taurate Drugs 0.000 description 3
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 3
- JYEUMXHLPRZUAT-UHFFFAOYSA-N 1,2,3-triazine Chemical compound C1=CN=NN=C1 JYEUMXHLPRZUAT-UHFFFAOYSA-N 0.000 description 2
- OUCGLXKNITVPJS-OUKQBFOZSA-N 2-ethylhexyl (e)-3-phenylprop-2-enoate Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=CC=C1 OUCGLXKNITVPJS-OUKQBFOZSA-N 0.000 description 2
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 2
- ZDHRAACDPXUCHC-UHFFFAOYSA-N 3,4-diethyl-2-hexoxyphenol;5-methoxy-4-phenyltriazine Chemical compound COC1=CN=NN=C1C1=CC=CC=C1.CCCCCCOC1=C(O)C=CC(CC)=C1CC ZDHRAACDPXUCHC-UHFFFAOYSA-N 0.000 description 2
- VTQVLCXOOIFPBB-UHFFFAOYSA-N 4-ethyl-5-hexyl-1H-triazin-6-one Chemical compound C(C)C1=C(C(NN=N1)=O)CCCCCC VTQVLCXOOIFPBB-UHFFFAOYSA-N 0.000 description 2
- 201000009030 Carcinoma Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000331121 Krameria lappacea Species 0.000 description 2
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 2
- 206010042496 Sunburn Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- -1 alcohol benzoic ethers Chemical class 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- MTZQAGJQAFMTAQ-UHFFFAOYSA-N ethyl benzoate Chemical compound CCOC(=O)C1=CC=CC=C1 MTZQAGJQAFMTAQ-UHFFFAOYSA-N 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 2
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 description 2
- RDOXTESZEPMUJZ-UHFFFAOYSA-N methyl phenyl ether Natural products COC1=CC=CC=C1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 description 2
- 229960001679 octinoxate Drugs 0.000 description 2
- 229960005323 phenoxyethanol Drugs 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010012218 Delirium Diseases 0.000 description 1
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- AKQOBHZKBDHWQI-BZEFIUHZSA-N O[C@H]1C[C@@H](CCC1)N1C(C2(C3=C1N=C(N=C3)NC1=CC=C(C=C1)S(=O)(=O)NC([2H])([2H])[2H])CC2)=O Chemical compound O[C@H]1C[C@@H](CCC1)N1C(C2(C3=C1N=C(N=C3)NC1=CC=C(C=C1)S(=O)(=O)NC([2H])([2H])[2H])CC2)=O AKQOBHZKBDHWQI-BZEFIUHZSA-N 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 102000003425 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- 230000006750 UV protection Effects 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- RFFPKXOXDLSOJI-UHFFFAOYSA-N azanium;2-(methylamino)ethanesulfonate Chemical compound N.CNCCS(O)(=O)=O RFFPKXOXDLSOJI-UHFFFAOYSA-N 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 229940127108 compound 5g Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000000806 elastomer Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 208000030208 low-grade fever Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001835 salubrious effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 231100000075 skin burn Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to cosmetic technical fields, and in particular to a kind of sun-proof synergistic compound and preparation method thereof.The sun-proof synergistic compound raw material includes Indian beech extract, krameria triandra root extract.Achieve the purpose that with the synergistic effect by a variety of different mechanism to sun-screening agent synergy, to reduce the additive amount of sun-screening agent.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of sun-proof synergistic compound and preparation method thereof.
Technical background
After skin receives ultraviolet light overexposure, epidermal cell can be damaged；Tyrosinase is activated, accelerates pigment synthesis, is broken
The moisture-keeping functions of bad skin, make skin become drying, and the elastic fibers allowed in skin corium is damaged, and generates microgroove, are shining strongly
It penetrates down, can also cause skin inflammation, burn.When having abnormal case, then it can become pigmentosa cutaneum carcinoma etc..
After disposable long period ultraviolet light irradiates skin, there is more chronic erythema through a few hours to more than 10 hours skin
(sunburn), color is scarlet, hydroderma, seriously can all play blister.Erythema reaction in second day peaks after solarization, passes through
Erythema subsides within one week or so, there is exfoliation and pigmentation, feels skin burns pain, and severe patient can such as send out with general reaction
, weak, nauseous and general malaise or even there is palpitaition, delirium and shock at headache in heat.
It is sun-proof to refer to prevent the purpose of skin is by tanned, sunburn to reach to take certain methods ultraviolet to obstruct or absorb
Line.The main ultraviolet light type for obstructing or absorbing has UVA (long wave ultraviolet), UVB (ultraviolet B radiation) and UVC, and (shortwave is purple
Outside line), different ultraviolet lights is for the injury difference of skin.Ultraviolet light is to the extent of injury of human skin：1st, UVA, wave
Long 320~420nm, there is a very strong penetration power, and UVA can go directly the skin corium of skin, destroy elastomer and collagen is fine
Dimension, by skin tanning.2nd, UVB, 275~320nm of wavelength, to human body have erythema effect, can promote internal mineral metabolism with
The formation of vitamin D, but long-term or excessive exposure can enable skin tanning, and cause red and swollen decortication.3rd, UVC, wavelength 200~
275nm, there is a great harm for human body, short irradiation can skin ambustion, long-term or high intensity illumination can also cause cutaneum carcinoma.
General sun-proof method:Smear sunscreen product, using sunproof clothes and other items, edible sun-proof food etc..Sunscreen product is divided into physics
Sun-proof, chemical sunscreen, biology are sun-proof；Wherein, the height of SPF can reflect the big of sunscreen product UV protection ability
It is small.Part sunscreen product can add in sun-proof synergist, it is therefore an objective to the additive amount of sun-screening agent be reduced to the greatest extent, to reach higher safety
Property and better skin sense.Present sun-proof synergist is high molecular polymer mostly, and principle is one by shape on the skin
Layer film enables sun-screening agent uniformly spread on the surface of skin, so as to improve spf value.The film skin sense formed is relatively viscous, for
It is required that salubrious consumer demand free of a burden is obviously unable to reach, and these high molecular polymers be all by artificial synthesized,
It is not suitable for the formula of natural demand yet.Therefore, a kind of new natural sun-prevention synergist is researched and developed to be of great significance.
Invention content
For these reasons, applicant has found a kind of new natural sun-prevention synergistic composition by multiple creative research；
There is compound of the present invention the synergistic effect by a variety of different mechanism to achieve the purpose that sun-screening agent synergy, to reduce sun-screening agent
Additive amount.
To solve above-mentioned technical proposal, technical solution provided by the invention is as follows：
A kind of sun-proof synergistic compound, the sun-proof synergistic compound raw material include Indian beech extract, krameria triandra
Root extract.
The weight ratio of the Indian beech extract and krameria triandra root extract is (0.5-1)：(0.5-1).
The weight ratio of the Indian beech extract and krameria triandra root extract is 1:1.
The sun-proof synergistic compound raw material includes Indian beech extract, krameria triandra root extract, bisabolol, ginger
Root extract, galactolipin araban, Flos Tagetis Erectae extract, lysolecithin, Scleroglucan, xanthans, budding short stalk enzyme
Polysaccharide.
The sun-proof synergistic compound includes the raw material of following weight percent：Indian beech extract, the 1- of 1-90%
90% krameria triandra root extract, the bisabolol of 1-10%, the ginger-root extract of 1-10%, 1-20% galactolipin Ah
Draw the xanthan of primary glycan, the Flos Tagetis Erectae extract of 1-90%, the lysolecithin of 1-5%, the Scleroglucan of 1-5%, 1-5%
The budding short stalk enzyme polysaccharide of glue, 1-5%.
The sun-proof synergistic compound is applied in beauty.
Application of the sun-proof synergistic compound in sunscreen product.
A kind of preparation method of sun-proof synergistic compound, includes the following steps：Water intaking Calusena lansium extract, krameria triandra root
Extract is heated to 40-45 DEG C, is uniformly mixed, and opens homogeneous and is stirred 5-10 minutes, and cooling and stirring is to replying 20-25
℃。
A kind of preparation method of sun-proof synergistic compound, includes the following steps：Water intaking Calusena lansium extract, krameria triandra root
Extract, bisabolol, ginger-root extract, galactolipin araban, Flos Tagetis Erectae extract, lysolecithin, Scleroglucan,
Xanthans, budding short stalk enzyme polysaccharide, are heated to 40-45 DEG C, are uniformly mixed, open homogeneous and be stirred 5-10 minutes, cool down
Stirring extremely replys 20-25 DEG C.The preferred resistant to pollution composition：
Specific embodiment
Understand to make the object, technical solutions and advantages of the present invention clearer, With reference to embodiment, to this
Invention is further described.It should be understood that these descriptions are merely illustrative, and it is not intended to limit the scope of the present invention.This
Outside, in the following description, the description to known features and technology is omitted, to avoid idea of the invention is unnecessarily obscured.
Present invention Indian beech (PONGAMIA PINNATA) extract described above is criticized purchased from Givaudan companies of Britain
Number be 20160903.
Krameria triandra (KRAMERIA TRIANDRA) root extract of the present invention is purchased from Croda companies of Britain, lot number
It is 20160816.
Flos Tagetis Erectae extract of the present invention is purchased from KEMIN companies of the U.S., lot number 20160816.
Purchased from Lonza companies of the U.S., lot number 20160903 described in galactolipin araban of the present invention.
The different embodiment compositions of table 1
Preparation method：
Water intaking Calusena lansium extract, krameria triandra root extract, bisabolol, ginger-root extract, galactolipin Arab gather
Sugar, Flos Tagetis Erectae extract, lysolecithin, Scleroglucan, xanthans, budding short stalk enzyme polysaccharide, low-grade fever is to 40-45 DEG C, stirring
It is uniformly mixed, opens homogeneous and be stirred 5-10 minutes, cooling and stirring to 20-25 DEG C of reply.
Test example：
Compound prepared by embodiment 1-3 is prepared into suncream and tests by the following method, and result of the test is shown in Table
1。
Test equipment：MAPADA UV-1600PC SPF detectors
Test example 1：
Formula of sun screen：EDETATE SODIUM 0.05g, ethylhexyl methoxy cinnamate 8g, double-ethyl hexyl oxy phenol methoxy benzene
The own ester 1g of base triazine 2g, diethylamino oxybenzene formylbenzoate, Uvinul T 150 1.1g, Homosalate 3.3g, C12-15
Alcohol benzoic ether 2g, methylene bis-benzotriazolyl tetramethyl butyl phenol 3g, ammonium acryloyl taurate/VP copolymer
1.5g, glycerine 8g, parahydroxyacet-ophenone 0.5g, Phenoxyethanol 0.5g, water 69.05g.
Preparation method：Water, EDETATE SODIUM are added in water phase kettle, it is complete to be heated to 80-85C stirring and dissolvings；By methoxy
Base 2-Ethylhexyl cinnamate, bis-ethylhexoxyphenol methoxyphenyl triazine, the own ester of diethylamino oxybenzene formylbenzoate, ethyl
Hexyl triazinone, Homosalate, C12-15 alcohol benzoic ethers, methylene bis-benzotriazolyl tetramethyl butyl phenol, acryloyl two
N-methyltaurine ammonium/VP copolymers are added in oil phase kettle, and it is complete to be heated to 80-85 DEG C of stirring and dissolving.
Test case 2
Formula of sun screen：EDETATE SODIUM 0.05g, ethylhexyl methoxy cinnamate 8g, double-ethyl hexyl oxy phenol methoxy benzene
The own ester 1g of base triazine 2g, diethylamino oxybenzene formylbenzoate, Uvinul T 150 1.1g, Homosalate 3.3g, C12-15
Alcohol benzoic ether 2g, methylene bis-benzotriazolyl tetramethyl butyl phenol 3g, ammonium acryloyl taurate/VP copolymer
1.5g, glycerine 8g, parahydroxyacet-ophenone 0.5g, Phenoxyethanol 0.5g, water 64.05g, the sun-proof synergistic compound 5g of the present invention.
Preparation method：Water, EDETATE SODIUM are added in water phase kettle, it is complete to be heated to 80-85C stirring and dissolvings；By methoxy
Base 2-Ethylhexyl cinnamate, bis-ethylhexoxyphenol methoxyphenyl triazine, the own ester of diethylamino oxybenzene formylbenzoate, ethyl
Hexyl triazinone, Homosalate, C12-15 alcohol benzoic ethers, methylene bis-benzotriazolyl tetramethyl butyl phenol, the present invention are anti-
Solarization synergistic compound, ammonium acryloyl taurate/VP copolymer are added in oil phase kettle, and it is molten to be heated to 80-85 DEG C of stirring
Solution is complete.
Table 2SPF values compare
| Test case 1 | Test case 2 | |
| Embodiment 1 | 31 | 55 |
| Embodiment 2 | 31 | 42 |
| Embodiment 3 | 31 | 48 |
Conclusion (of pressure testing)：This sun-proof synergistic compound has spf value apparent synergistic effect.
Claims (9)
1. a kind of sun-proof synergistic compound, which is characterized in that the sun-proof synergistic compound raw material includes Indian beech extract, secret
Shandong ratanhia extract.
2. a kind of sun-proof synergistic compound according to claim 1, which is characterized in that the Indian beech extract and Peru
The weight ratio of ratanhia extract is (0.5-1)：(0.5-1).
3. a kind of sun-proof synergistic compound according to claim 1, which is characterized in that Indian beech extract draws smooth with Peru
The weight ratio of Buddhist nun's root extract is 1:1.
A kind of 4. sun-proof synergistic compound according to claim 1, which is characterized in that the sun-proof synergistic compound raw material
Including Indian beech extract, krameria triandra root extract, bisabolol, ginger-root extract, galactolipin araban, Wan Shou
Chrysanthemum extract, lysolecithin, Scleroglucan, xanthans, budding short stalk enzyme polysaccharide.
5. a kind of sun-proof synergistic compound according to claim 4, which is characterized in that the sun-proof synergistic compound includes
The raw material of following weight percent：The Indian beech extract of 1-90%, the krameria triandra root extract of 1-90%, 1-10%
Bisabolol, the ginger-root extract of 1-10%, the galactolipin araban of 1-20%, the Flos Tagetis Erectae extract of 1-90%, 1-
5% lysolecithin, the Scleroglucan of 1-5%, the xanthans of 1-5%, 1-5% budding short stalk enzyme polysaccharide.
6. it is applied in beauty according to any one of the claim 1-5 compounds.
7. according to application of any one of the claim 1-5 compounds in sunscreen product.
8. a kind of preparation method of sun-proof synergistic compound, which is characterized in that include the following steps：It fetches water Calusena lansium extract, secret
Shandong ratanhia extract, is heated to 40-45 DEG C, is uniformly mixed, and opens homogeneous and is stirred 5-10 minutes, cooling and stirring is extremely
Reply 20-25 DEG C.
9. the preparation method of a kind of sun-proof synergistic compound according to claim 8, which is characterized in that including following step
Suddenly：Fetch water Calusena lansium extract, krameria triandra root extract, bisabolol, ginger-root extract, galactolipin araban, ten thousand
Longevity chrysanthemum extract, lysolecithin, Scleroglucan, xanthans, budding short stalk enzyme polysaccharide, are heated to 40-45 DEG C, are stirred
It is even, it opens homogeneous and is stirred 5-10 minutes, cooling and stirring to 20-25 DEG C of reply.
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| CN110559682A (en) * | 2019-09-23 | 2019-12-13 | 北京天然纳美健康科技有限公司 | Plant extract nanoparticle and preparation method and application thereof |
| WO2023224944A1 (en) * | 2022-05-16 | 2023-11-23 | Colgate-Palmolive Company | Sunscreen composition comprising: a metal oxide, spf active ingredient; and one or more spf enhancement component comprising a photostabilizer, an antioxidant, or a combination thereof |
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| CN110559682A (en) * | 2019-09-23 | 2019-12-13 | 北京天然纳美健康科技有限公司 | Plant extract nanoparticle and preparation method and application thereof |
| WO2023224944A1 (en) * | 2022-05-16 | 2023-11-23 | Colgate-Palmolive Company | Sunscreen composition comprising: a metal oxide, spf active ingredient; and one or more spf enhancement component comprising a photostabilizer, an antioxidant, or a combination thereof |
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