CN108144146A - A kind of implantable unilateral side axis self-balancing micro-axial blood pump - Google Patents
A kind of implantable unilateral side axis self-balancing micro-axial blood pump Download PDFInfo
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- CN108144146A CN108144146A CN201810072872.7A CN201810072872A CN108144146A CN 108144146 A CN108144146 A CN 108144146A CN 201810072872 A CN201810072872 A CN 201810072872A CN 108144146 A CN108144146 A CN 108144146A
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- rotor
- guide vane
- blade
- rear guide
- sleeve
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- 239000008280 blood Substances 0.000 title claims abstract description 49
- 210000004369 blood Anatomy 0.000 title claims abstract description 49
- 238000009434 installation Methods 0.000 claims abstract description 7
- 229920003266 Leaf® Polymers 0.000 claims description 15
- 238000010276 construction Methods 0.000 abstract description 7
- 206010019280 Heart failures Diseases 0.000 abstract description 3
- 208000007536 Thrombosis Diseases 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 3
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 229910001069 Ti alloy Inorganic materials 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000023555 blood coagulation Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- 229910000976 Electrical steel Inorganic materials 0.000 description 1
- 238000005299 abrasion Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000000696 magnetic material Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 210000000707 wrist Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Mechanical Engineering (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
A kind of implantable unilateral side axis self-balancing micro-axial blood pump, for assisting the blood circulation of failure heart.The blood pump includes sleeve, the pump housing being arranged in sleeve and the driving coil being arranged on outside sleeve；The pilot blade and the rear guide vane of rotor rear end setting that the pump housing includes rotor, rotor front end is set；Spacing is equipped between pilot blade and rotor, rotor is connect with rear guide vane contact, and pilot blade, rear guide vane are fixed on sleeve lining；Internal rotor is embedded with permanent magnet, and driving coil is downstream staggered with permanent magnet in the installation site of mid-length distance L, sleeve, rotor, pilot blade and the concentric setting of rear guide vane.Blood pump is using unilateral axle construction, rotor is only contacted with rear guide vane, it is not in contact between pilot blade and rotor, since the axial force of coil and magnetic core is in close contact the convex semispherical structure of rotor and the recessed hemisphere of rear guide vane between rear guide vane and rotor, it avoids haemocyte and causes hematoclasis and the formation of thrombus into its gap, ensure stable operation.
Description
Technical field
The present invention relates to a kind of implantable unilateral side axis self-balancing micro-axial blood pump, for assisting the blood of failure heart
Cycle, belongs to biomedical engineering technology field.
Background technology
World Health Organization's statistics display, angiocardiopathy are always to threaten the first killer of human health, are accounted for global total
30% or so of death toll, the effective way for treating whole latter stage heart failure are heart transplant or use implanted indirect labor's heart
It is dirty.Although heart transplant has obtained very ten-strike, heart donor problem is difficult to solve, and develops the miniature blood of long-term implantable
It pumps particularly important and urgent.For the blood pump of present clinical practice mainly based on axial-flow pump, the flow performance of axial-flow pump compares centrifugal pump
It is good, larger blood flow can be provided.Flow field inside blood pump is extremely complex, and the internal structure of blood pump is to the flow resistance of blood
Have a significant impact with the efficiency of blood pump, haemocyte also occurs that rupture causes in blood pump under relatively high shear stress environment molten
Blood.Due to presence of the existing shaft type axial-flow pump in pilot blade and rotor contact zone and rear guide vane and rotor contact zone, lead to these
There is amount of heat generation in region and shear stress is larger, and gap location is the main portions that blood coagulation occurs, so as to the life structure to patient
It is threatened into great；The friction of rotor and front and rear guide vane can be led to by eliminating gap simultaneously, reduce the service life of blood pump.Therefore one is provided
Kind can reduce gap, while can be extremely important to avoid the axial-flow pump of excessive friction.
Invention content
The purpose of the present invention is intended to provide a kind of reduction gap, blood pump long lifespan, the implantable list for avoiding excessive friction
Side axle self-balancing micro-axial blood pump.
To achieve the above object, the technical solution adopted by the present invention is that：A kind of implantable unilateral side axis self-balancing Minisize axial
It bleeds pump, including sleeve, the pump housing being arranged in sleeve and the driving coil being arranged on outside sleeve；The pump housing includes rotor, turns
The pilot blade of sub- front end setting and the rear guide vane of rotor rear end setting；It is characterized in that：Spacing is equipped between pilot blade and rotor,
Rotor is connect with rear guide vane contact, and pilot blade, rear guide vane are fixed on sleeve lining；Internal rotor is embedded with permanent magnet, drives line
Circle is downstream staggered with permanent magnet in the installation site of mid-length distance L, and sleeve, rotor, pilot blade and rear guide vane are coaxial
The heart is set.
Pilot blade includes front axle, and front axle radial equipartition sets four pilot blade blades, and the outer rim of four pilot blade blades is consolidated
It is scheduled on sleeve lining.
Rotor rear end be equipped with convex hemisphere, rear guide vane include rear axle, rear axle radial equipartition set four rear guide vane blades, four
The outer rim of rear guide vane blade is fixed on sleeve lining, and rear axle front end is equipped with recessed hemisphere, rotor rear portion stretch into rear guide vane vane inside edge,
Convex hemisphere is located in recessed hemisphere and the two contact connects；Sleeve, rotor, front axle and the concentric setting of rear axle.
Rotor outer surface is set there are two helical form linear leaf, sets that there are four the short leaves of helical form between two helical form linear leafs
Piece.
Using unilateral axle construction, i.e. rotor is only connect and contactless with pilot blade with rear guide vane for blood pump provided by the invention,
Form unilateral axle construction；The recessed hemisphere that the convex hemisphere that rotor is equipped with is equipped with rear guide vane, composition semiglobe support, is formed
Unilateral axle construction is used for supporting rotor；Driving coil center is downstream staggered with internal rotor permanent magnet center distance, in blood
During pump operation, since driving coil center is in permanent magnet center downstream, the electromagnetism that rotor inner magnetic core is directed toward downstream can be given
Power, for offsetting the reaction force of direction upstream that rotor blade driving blood flow is brought, electromagnetic force and fluid counterforce
Size increases with the increase of driving coil power, and it is certainly flat to reach electromagnetic force and blood reaction force dynamic under arbitrary operating mode
Weighing apparatus；Sleeve, rotor, pilot blade and rear guide vane are coaxial, ensure stability during operation.Between being equipped between blood pump pilot blade and rotor
Away from the one hand the connection of cancellation rotor and pilot blade avoids the friction between rotor and pilot blade；On the other hand, pilot blade with
Enough spaces can be flowed out between rotor, are avoided due to the excessive caused hematoclasis of shear stress and the formation of thrombus；
Electromagnetic force and fluid counterforce size increase with the increase of driving coil power, reach dynamic under arbitrary operating mode from
Balance.Dynamic self-balance characteristic is avoided is rubbed on startup by pre-tightening the conventional unilateral axis blood pump of dynamic balance blood reaction force
The problem of nuzzling up big, balance be unable to reach when off rating run, so as to ensure in start-up course or non-specified work for a long time
Stable operation under condition.
The center of recessed hemisphere is provided with vesicle, it is possible to reduce convex hemisphere 8 and recessed dome contact area avoid friction from drawing
The hot-spot risen, and the mismachining tolerance of a part can be born.
Compared with prior art, the present invention haing the following advantages and high-lighting effect：
1st, conventional axial flow blood pump leads to the convex hemisphere and recessed half in axle construction due to the reaction force by blood in operation process
Aggravation is worn between ball, reduced lifetime and over time rotor and the gradual increase in gap of front and rear guide vane contact position are easy
Form blood coagulation；And axis self-balancing micro-axial blood pump in implantable unilateral side provided by the invention, since there are coil and magnetic cores
Axial force can offset the reaction force of blood, avoid causing between rotor contacts with rear guide vane due to the abrasion at axis wrist
The defects of gap increase, axial-flow pump reduced lifetime；
2nd, traditional axial-flow pump is due to the presence in front and rear guide vane and rotor junctional area gap, and a kind of implantable unilateral side axis is certainly flat
It is not in contact between the micro-axial blood pump pilot blade and rotor of weighing apparatus, due to the axial direction of coil and magnetic core between rear guide vane and rotor
Active force is in close contact the convex semispherical structure of rotor and the recessed semiglobe of rear guide vane, enters therebetween so as to avoid haemocyte
Gap and cause hematoclasis and the formation of thrombus；
3rd, since driving coil increases to the power of rotor inner magnetic core and the reaction force of blood with the increase of power, so as to protect
The dynamic self-balance under each operating mode has been demonstrate,proved, it, can be non-compared with the conventional unilateral axis axial-flow pump using pretightning force installation
It is run steadily in the long term under declared working condition；
4th, traditional axial-flow pump since rotor is contacted with front and rear guide vane, increases the difficulty of blood pump processing and installation；And this
The implantable unilateral side axis self-balancing micro-axial blood pump provided is invented using unilateral axle construction, rotor only connects with rear guide vane
It touches, reduces the difficulty of processing of blood pump, and be more easily installed.
Description of the drawings
Fig. 1 is the structure diagram of the present invention；
Fig. 2 is the structure diagram of pump body portion；
Fig. 3 is the sectional view of the pump housing and sleeve；
Fig. 4 is the sectional view at Fig. 1 P-P；
Fig. 5 is the left view of Fig. 1；
Fig. 6 is the right view of Fig. 1.
In figure：1 --- pilot blade blade, 2-rotor blade, 201-linear leaf, 202-short blade, 3-rear guide vane leaf
Piece, 4-pilot blade, 5-rotor, 6-rear guide vane, 7-recessed hemisphere, 8-convex hemisphere, pyramidal structure at 9-rotor inlet, 10-
Pyramidal structure at rotor outlet, 11-internal rotor permanent magnet, driving coil at 12-sleeve, 13-sleeve, 14-vesicle,
15-front axle, 16-rear axle, A-spacing, L-distance.
Specific embodiment
The invention will be further described below in conjunction with the accompanying drawings.As shown in Figures 1 and 3：One kind provided by the invention can plant
Enter formula unilateral side axis self-balancing micro-axial blood pump, including sleeve 13, the pump housing being arranged in sleeve 13 and be arranged on sleeve 13
Outer driving coil 12；The pilot blade 4 and the rear guide vane 6 of 5 rear end of rotor setting that the pump housing includes rotor 5,5 front end of rotor is set；
It is characterized in that：Spacing A is equipped between pilot blade 4 and rotor 5, rotor 5 connect with 6 contact of rear guide vane, pilot blade 4, after lead
Leaf 6 is fixed on 13 inner wall of sleeve；Referring to Fig. 4；5 inside of rotor is embedded with permanent magnet 11, and driving coil 12 is with permanent magnet 11 in length
Intermediate installation site is downstream staggered and has distance L, sleeve 13, the 6 concentric setting of rotor 5, pilot blade 4 and rear guide vane.
Referring to Fig. 5：Pilot blade 4 includes front axle 15, and 15 radial equipartition of front axle sets four pilot blade blades 1, and four leading
The outer rim of leaf blade 1 is welded on 13 inner wall of sleeve.The quantity of pilot blade blade 1 is not limited to four.
Referring to Fig. 6：Rear guide vane 6 includes rear axle 16, and 16 radial equipartition of rear axle sets four rear guide vane blades 3, rear guide vane leaf
The quantity of piece 3 is not limited to four, and the outer rim of four rear guide vane blades 3 is welded on 13 inner wall of sleeve, and rear axle front end is equipped with recessed hemisphere
7；Referring to Fig. 1 and Fig. 3；5 rear end of rotor is equipped with convex hemisphere 8, and 3 inner edge of rear guide vane blade is stretched at 5 rear portion of rotor, convex hemisphere 8 is located at
In recessed hemisphere 7 and the two contact connects；Sleeve 13, the 16 concentric setting of rotor 5, front axle 15 and rear axle.
5 outer surface of rotor is equipped with rotor blade 2, and rotor blade 2 includes two helical form linear leafs 201, two helical forms
It is set between linear leaf 201 there are four helical form short blade 202, two linear leafs 201 are arranged on 5 front middle part of rotor, four short leaves
Piece 202 is arranged on 5 middle part of rotor.
Prior art rotor blade is two helical form linear leafs, and linear leaf manufacturing procedure is complicated, short blade and linear leaf
Compared to easily processing.After adding in short blade so that rotor blade density increases, and effectively improves blood pump hydraulic efficiency.And it adds in
After short blade, at the same conditions, since the blade gross area increases so that the mitigation of blade unit area loading, is conducive to improve
The blood pump service life.Meanwhile add in after short blade so that the reflux of rotor blade exit region is reduced, speed and pressure are more uniform, have
Effect reduces shearing stress, so as to reduce the damage to blood.
Referring to Fig. 1 and Fig. 3；The center of recessed hemisphere 7 is provided with vesicle 14, it is possible to reduce convex hemisphere 8 connects with recessed hemisphere 7
Contacting surface is accumulated, and avoids rotor and hot-spot caused by rear guide vane friction, and can bear the mismachining tolerance of a part；Also play fixation
The effect of rotor circumferential position forms unilateral axle construction.
In addition to the permanent magnet embedded in internal rotor, remaining part is un-conducted magnetic material in the pump housing, such as titanium alloy.Because
Titanium alloy is non-magnetic, therefore can obtain larger transfer of torque, and titanium alloy light weight and with good bio-compatible
Property.Driving coil center is from the downstream changing of the relative positions a certain distance L of permanent magnet center in rotor during installation, when axial flow blood pump operated
Cheng Zhong, due to the interaction of permanent magnet in coil and rotor, the reaction force that counteracting blood is brought is so as to ensure rotor with after
The good contact of guide vane makes rotor keep smaller gap with rear guide vane.
Electromagnetic drive coil 12 uses silicon steel sheet electromagnetic coil, is arranged on outside sleeve, electromagnetic drive is controlled by controller
Size of current and direction in coil generate alternating magnetic field driving rotor rotation, and rotating speed can reach 11000~13000 revs/min,
So as to generate the pressure difference of 100~120mmHg, driving blood is circulated.
Electromagnetic force and the size of blood reaction force increase with the increase of driving coil power, so as in any operating mode
Under can reach dynamic self-balance, compared with conventional pretightning force unilateral side axis blood pump, it is ensured that on startup or for a long time it is non-
Stable operation under declared working condition.
Claims (7)
1. a kind of implantable unilateral side axis self-balancing micro-axial blood pump, including sleeve, the pump housing being arranged in sleeve and sets
Put the driving coil outside sleeve；The pilot blade and the rear guide vane of rotor rear end setting that the pump housing includes rotor, rotor front end is set；
It is characterized in that：Pilot blade（4）With rotor（5）Between be equipped with spacing（A）, rotor（5）With rear guide vane（6）Contact connects, preceding
Guide vane（4）, rear guide vane（6）It is fixed on sleeve（13）Inner wall；Rotor（5）Inside is embedded with permanent magnet（11）, driving coil（12）With
Permanent magnet（11）Downstream being staggered in the installation site of mid-length has distance（L）, sleeve（13）, rotor（5）, pilot blade（4）
And rear guide vane（6）Concentric setting.
2. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as described in claim 1, it is characterised in that：Pilot blade
（4）Including front axle（15）, front axle（15）Radial equipartition sets multi-disc pilot blade blade（1）, multi-disc pilot blade blade（1）Outer rim
It is welded on sleeve（13）Inner wall.
3. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as claimed in claim 2, it is characterised in that：Pilot blade
Blade（1）It is four.
4. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as claimed in claim 3, it is characterised in that：Rear guide vane
（6）Including rear axle（16）, rear axle（16）Radial equipartition sets multi-disc rear guide vane blade（3）, multi-disc rear guide vane blade（3）Outer rim
It is welded on sleeve（13）Inner wall, rear axle front end are equipped with recessed hemisphere（7）；Rotor（5）Rear end is equipped with convex hemisphere（8）, rotor（5）Rear portion
Stretch into rear guide vane blade（3）Inner edge, convex hemisphere（8）Positioned at recessed hemisphere（7）Interior and the two contact connects；Sleeve（13）, rotor
（5）, front axle（15）And rear axle（16）Concentric setting.
5. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as claimed in claim 4, it is characterised in that：Rear guide vane
Blade（3）It is four.
6. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as described in claim 1 to 5 any one, feature
It is：Rotor（5）Outer surface is equipped with rotor blade（2）, rotor blade（2）Including two helical form linear leafs（201）, two spiral shells
Revolve shape linear leaf（201）Between set there are four helical form short blade（202）.
7. a kind of implantable unilateral side axis self-balancing micro-axial blood pump as claimed in claim 6, it is characterised in that：It is two long
Blade（201）It is arranged on rotor（5）Front middle part, four short blades（202）It is arranged on rotor（5）Middle part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810072872.7A CN108144146A (en) | 2018-01-25 | 2018-01-25 | A kind of implantable unilateral side axis self-balancing micro-axial blood pump |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810072872.7A CN108144146A (en) | 2018-01-25 | 2018-01-25 | A kind of implantable unilateral side axis self-balancing micro-axial blood pump |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108144146A true CN108144146A (en) | 2018-06-12 |
Family
ID=62456769
Family Applications (1)
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|---|---|---|---|
| CN201810072872.7A Withdrawn CN108144146A (en) | 2018-01-25 | 2018-01-25 | A kind of implantable unilateral side axis self-balancing micro-axial blood pump |
Country Status (1)
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Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US11185677B2 (en) | 2017-06-07 | 2021-11-30 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| CN113730792A (en) * | 2021-09-24 | 2021-12-03 | 北京航空航天大学 | Extracorporeal circulation magnetic suspension mixed flow blood pump |
| CN114099940A (en) * | 2021-11-25 | 2022-03-01 | 山东大学 | A mixed-flow blood pump and an extracorporeal circulation auxiliary system |
| US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US11724089B2 (en) | 2019-09-25 | 2023-08-15 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| US12102815B2 (en) | 2019-09-25 | 2024-10-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible pump housings |
| US12121713B2 (en) | 2019-09-25 | 2024-10-22 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible blood conduits |
| US12161857B2 (en) | 2018-07-31 | 2024-12-10 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| US12220570B2 (en) | 2018-10-05 | 2025-02-11 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11185677B2 (en) | 2017-06-07 | 2021-11-30 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11717670B2 (en) | 2017-06-07 | 2023-08-08 | Shifamed Holdings, LLP | Intravascular fluid movement devices, systems, and methods of use |
| US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11229784B2 (en) | 2018-02-01 | 2022-01-25 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US12076545B2 (en) | 2018-02-01 | 2024-09-03 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US12161857B2 (en) | 2018-07-31 | 2024-12-10 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| US12220570B2 (en) | 2018-10-05 | 2025-02-11 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US12102815B2 (en) | 2019-09-25 | 2024-10-01 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible pump housings |
| US11724089B2 (en) | 2019-09-25 | 2023-08-15 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| US12121713B2 (en) | 2019-09-25 | 2024-10-22 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible blood conduits |
| CN113730792B (en) * | 2021-09-24 | 2022-09-27 | 北京航空航天大学 | A kind of extracorporeal circulation magnetic suspension mixed flow blood pump |
| CN113730792A (en) * | 2021-09-24 | 2021-12-03 | 北京航空航天大学 | Extracorporeal circulation magnetic suspension mixed flow blood pump |
| CN114099940A (en) * | 2021-11-25 | 2022-03-01 | 山东大学 | A mixed-flow blood pump and an extracorporeal circulation auxiliary system |
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