CN108143650A - A kind of anti-aging Essence and preparation method thereof - Google Patents

Abstract

The present invention discloses a kind of anti-aging Essence and preparation method thereof, and the weight percent of each component is in the Essence:Aqueous soluble ginseng's saponin(e accounts for 0.3% 15%, and chlorella extract accounts for 0.1% 10%, and oil phase accounts for 40% 80%, and emulsifier accounts for 5% 25%, and assistant for emulsifying agent accounts for 4% 20%, and water phase accounts for 10% 20%, according to the market demand, can add in 0.1% 1.0% volatile oil or essential oils.During preparation, Aqueous soluble ginseng's saponin(e and chlorella extract are dissolved in water, form water phase；Oil phase and emulsifier, assistant for emulsifying agent are uniformly mixed, form oil phase；Water phase is slowly added in the oil phase of high-speed stirred, it is fully emulsified, form microemulsion；Or after being stirred oil phase and water phase and forming colostrum, handled using high-pressure homogeneous equipment, form microemulsion；According to the market demand, suitable essential oil or plant volatile oil are added in, is uniformly mixed up to anti-aging essence liquid product.The raw material sources of the present invention enrich, and preparation method is simple, and operability is strong, easily realizes industrialized production.

Description

A kind of anti-aging essence and preparation method thereof

technical field

The invention relates to an anti-aging essence and a preparation method thereof, belonging to the technical field of cosmetic processing.

Background technique

Skin aging is an inevitable phenomenon that occurs with age, but the accelerated pace of life in modern society, working overtime and staying up late, frequent use of computers, etc. will accelerate the aging process of the skin. With the continuous improvement of social and economic level and people's in-depth research on science, skin anti-aging research has become one of the hot spots in the fields of medicine and biology.

At present, there are many kinds of anti-aging cosmetics on the market, such as moisturizing, cell repairing, and free radical scavenging; and each cosmetic has different formulations and production techniques, and the drug permeation into the skin is different, and its anti-aging effect There are large differences and it is difficult to meet the needs of consumers.

Human skin is generally composed of epidermis, dermis, and subcutaneous tissue, as well as appendages such as sweat glands, cortical follicles, and hair follicles. The stratum corneum of the epidermis is the main barrier that affects the percutaneous absorption of products. Ordinary cosmetics are difficult to effectively penetrate the stratum corneum due to the limitation of technological conditions, and the effect of delaying skin aging is limited.

Ginsenoside (Ginsenoside) is a sterol compound, triterpene saponin, in addition to medicinal, it is also commonly used in cosmetics. Ginsenoside is the main active ingredient in Araliaceae plant ginseng, which can promote the blood circulation of subcutaneous capillaries, increase skin nutrition supply, and has good anti-ultraviolet damage effect, delaying skin aging. From a molecular perspective, ginsenosides mainly achieve its anti-aging function through four ways: by increasing the activity of SOD, CAT, and GSH2Px in the body, inducing the expression of SOD and CAT genes, and reducing the content of LPO and MDA to achieve its anti-aging effect; It realizes its anti-aging function by promoting the release of neurotransmitters, increasing the content of neurotransmitter transmitters (Ach), promoting the expression of TrkBmRNA in NBM neurons, and preventing excessive nitrate production by neurons; through the moderate regulation of the immune system at the cellular and molecular levels Regulate and delay aging; Ginsenosides can also achieve its anti-aging function by affecting cell cycle regulatory factors, aging gene expression, extending telomere length, and enhancing telomerase activity.

Chlorella is a high-quality green nutritious food, which has the advantages of high protein, low fat, low sugar, low calorie and rich in vitamins and mineral elements. Chlorella extract is rich in carotenoids, which can protect the skin from ultraviolet rays when used in cosmetics; and contains a large number of amino acids such as lysine, proline, glycine and alanine, which have the ability to restructure the skin and make the skin Smooth surface effect. Plus, chlorella extract prevents the breakdown of skin collagen and elastin and promotes more collagen synthesis.

The invention utilizes the advantages of the above-mentioned raw materials to develop an anti-aging skin essence by using water-soluble ginsenoside extracts and chlorella extracts to meet the needs of consumers.

Contents of the invention

The object of the present invention is to provide an anti-aging essence containing water-soluble ginsenoside and chlorella extract and a preparation method thereof.

The invention uses water-soluble ginsenosides and chlorella extracts as raw materials and adopts advanced nano-preparation technology to develop a pure natural anti-aging essence, which can effectively penetrate the stratum corneum and delay skin aging after long-term use.

An anti-aging essence of the present invention is composed of water-soluble ginsenoside, chlorella extract, oil phase, water phase, emulsifier, co-emulsifier, etc.; the mass percentage of each component in the product is: water-soluble ginseng Saponin accounts for 0.3%-15%, chlorella extract accounts for 0.1%-10%, oil phase accounts for 40%-80%, emulsifier accounts for 5%-25%, co-emulsifier accounts for 4%-20%, water phase It accounts for 10%-20%. According to market demand, 0.1%-1.0% volatile oil or essential oil can be added.

The weight ratio (Km value) of the emulsifier to the co-emulsifier is 0.7-5, more preferably 1.1-3.5, more preferably 1.5-2.5.

The oil phase is isopropyl myristate, glyceryl caprylate, isopropyl laurate, peanut oil, soybean oil, oleic acid, glyceryl monoacetate, glyceryl triacetate, isostearyl isostearyl , Isopropyl Palmitate, Ethyl Oleate, Ethyl Butyrate, Ethyl Octanoate, etc. or a mixture of more.

The oil phase is preferably isopropyl myristate, which has a certain penetration-promoting effect, is often used in the preparation of cosmetics, and can form a stable microemulsion with a high water-carrying capacity.

The emulsifier is egg yolk lecithin, soybean lecithin, polyethylene glycol 40 hydrogenated castor oil, Tween-80, Tween-20, Span-20, Span-80, sodium dioctyl thiosuccinate , polyoxyethylene-8-caprylic glycerin, etc., or a mixture of more than one.

The co-emulsifier is one or a mixture of absolute ethanol, propylene glycol, glycerin, n-butanol, 1,2-octanediol and the like.

The preferred dehydrated alcohol as the co-emulsifier has low viscosity, good fluidity of the product, and is safe and non-toxic.

The anti-aging essence can add a small amount of volatile oil or essential oil, including one or more mixtures of rose essential oil, jasmine essential oil, rosemary essential oil and osmanthus essential oil.

The preparation method of the anti-aging essence of the present invention is: preparing a water-in-oil microemulsion by high-speed homogenization or high-pressure homogenization. The specific steps are:

(1) Dissolving water-soluble ginsenosides and chlorella extract in water to form an aqueous phase;

(2) Mix the oil phase with the emulsifier and co-emulsifier evenly to form the oil phase;

(3) Slowly add the water phase to the high-speed stirring oil phase to fully emulsify to form a microemulsion; or stir the oil phase and water phase to form colostrum, and use high-pressure homogenization equipment to process to form a microemulsion;

(4) According to market demand, add volatile oil or essential oil to the microemulsion, mix well, and get the anti-aging essence product.

During preparation, all operations are carried out in a clean and sterile environment to ensure product quality.

Microemulsion is a new type of nano-scale carrier system with relatively promising research and development prospects. It is made of colostrum by stirring the oil phase, emulsifier and water phase. Prepared with a particle size of less than 100 nm, it can increase the penetration concentration gradient and increase the fluidity of the stratum corneum bilayer, thereby enhancing percutaneous penetration and absorption performance, and reducing the amount of active ingredients used. It is often used in pharmaceuticals and cosmetics industries. product development.

In order to give full play to the skin anti-aging effect of the active ingredient ginsenoside, the present invention dissolves it in the water phase, and then prepares the essence of the water-in-oil microemulsion through preparation methods such as high-speed milk homogenization or high-pressure homogenization, which can promote The transdermal penetration and absorption of ginsenoside and chlorella extract components can greatly improve the anti-aging effect of the skin; the raw material source of the present invention is abundant, and the materials are pure natural extracts, without adding other chemical synergists, with good safety and long-term Use can delay skin aging. The preparation method of the invention is simple, has strong operability, and is easy to realize industrialized production.

Detailed ways

The content of the present invention will be further described below in conjunction with the examples, but the present invention is not limited.

Example 1

Preparation of anti-aging essence: Weigh 3.0g of egg yolk lecithin, 10g of isopropyl myristate, add 3.0ml of absolute ethanol, stir and dissolve on a magnetic stirrer at a speed of 100 rpm, as the oil phase; weigh Ginsenoside 1.5g, chlorella extract 0.5g, add 3.5ml of water to dissolve and form water phase; under the high-speed disperser with 8000 rpm fast shear, add the above water phase to the oil phase, continue to stir and emulsify 10 min; take it out, add 0.2g of rose essential oil, mix evenly, and obtain a light yellow transparent essence. The average particle size of the product is 17.6nm as measured by a laser particle size analyzer.

Example 2

Preparation of anti-aging essence: Weigh 5.3g of soybean lecithin, 10.8g of caprylic glyceride, add 3ml of absolute ethanol, stir and dissolve at a speed of 100 rpm on a magnetic stirrer, and use it as the oil phase; weigh ginseng Saponin 2.0g, chlorella extract 0.6g, add water to dissolve and form a water phase; add the above water phase to the oil phase under the rapid shear of 12000 rpm in a high-speed disperser, continue to stir and emulsify for 13 min; take out , add 0.2g of sweet-scented osmanthus volatile oil, mix evenly, and obtain light yellow transparent essence. As measured by a laser particle size analyzer, the average particle size of the product is 14.9nm.

Example 3

Preparation of anti-aging essence: Weigh 8.6g of polyethylene glycol 40 hydrogenated castor oil, 20.1g of isopropyl laurate, add 4.3ml of 1,2-propanediol, stir and dissolve on a magnetic stirrer at a speed of 100 rpm , as the oil phase; weigh 2.0 g of ginsenosides and 1.5 g of chlorella extract, add water to dissolve and form a water phase; add the above water phase to the oil phase, stir and mix to form colostrum; take it out, and process it through high-pressure homogenization for 3 Then add 0.3g of rosemary essential oil and mix well to get a light yellow transparent essence. The average particle size of the product is 10.6nm as measured by a laser particle size analyzer.

Claims (8)

1. a kind of anti-aging Essence, it is characterised in that：The weight percent of each component is in product:Aqueous soluble ginseng's saponin(e 0.3%-15% is accounted for, chlorella extract accounts for 0.1%-10%, and oil phase accounts for 40%-80%, and emulsifier accounts for 5%-25%, and assistant for emulsifying agent accounts for 4%- 20%, water phase accounts for 10%-20%, according to the market demand, can add in 0.1%-1.0% volatile oil or essential oil.

2. the anti-aging Essence according to claim 1, it is characterised in that：The emulsifier and the weight of assistant for emulsifying agent It is 0.7~5 to measure ratio.

3. the anti-aging Essence according to claim 2, it is characterised in that：The emulsifier and the weight of assistant for emulsifying agent It is 1.5~2.5 to measure ratio.

4. the anti-aging Essence according to claim 1, it is characterised in that：The oil phase is isopropyl myristate, pungent Glycerol decanoate, isopropyl laurate, peanut oil, soybean oil, oleic acid, single triacetin, triacetyl glycerine, isostearoyl The mixture of one or more of different hard ester, isopropyl palmitate, ethyl oleate, ethyl butyrate, ethyl caprilate.

5. the anti-aging Essence according to claim 1, it is characterised in that：The emulsifier is egg yolk lecithin, soybean Lecithin, 40 rilanit special of polyethylene glycol, Tween-80, Tween-20, Arlacel-20, Arlacel-80, dioctylthio succinic acid The mixture of one or more of sodium, polyoxyethylene -8- octanoic acid glycerine.

6. the anti-aging Essence according to claim 1, it is characterised in that：The assistant for emulsifying agent is absolute ethyl alcohol, the third two One or more mixtures in alcohol, glycerine, n-butanol, 1,2- ethohexadiols.

7. the anti-aging Essence according to claim 1, it is characterised in that：The volatile oil or essential oil are rhodamine toner The mixture of one or more of oil, refined jasmine oil, Rosemary Oil and sweet osmanthus volatile oil.

8. according to the preparation method of claim 1-7 any one of them anti-aging Essences, which is characterized in that including walking as follows Suddenly：

（1）Aqueous soluble ginseng's saponin(e and chlorella extract are dissolved in water, form water phase；

（2）Oil phase and emulsifier, assistant for emulsifying agent are uniformly mixed, form oil phase；

（3）Water phase is slowly added in the oil phase of high-speed stirred, it is fully emulsified, form microemulsion；Or oil phase and water phase are stirred It mixes after forming colostrum, is handled using high-pressure homogeneous equipment, form microemulsion；

（4）According to the market demand, volatile oil or essential oil are added in microemulsion, is uniformly mixed and is produced to get anti-aging Essence Product.