CN108135501A

CN108135501A - For extracting the device and method of cardiovascular property

Info

Publication number: CN108135501A
Application number: CN201780003532.2A
Authority: CN
Inventors: 朴商纶; 高秉勋; 权用柱; 姜在珉; 金渊皓; 卢承佑; 尹永竣
Original assignee: Samsung Electronics Co Ltd
Current assignee: Samsung Electronics Co Ltd
Priority date: 2016-05-03
Filing date: 2017-05-02
Publication date: 2018-06-08
Also published as: JP2019516416A; EP3288447A1; EP3288447A4; KR20170124943A

Abstract

A kind of equipment for extracting cardiovascular property is provided.The equipment may include：First sensor is configured as measuring the vibration signal generated by the pulse wave of object；Second sensor is configured as the pulse wave signal of measurement object；Processor is configured as vibration signal and pulse wave signal based on measurement to perform and the relevant operation of cardiovascular property；Main body, installation first sensor, second sensor and processor.

Description

For extracting the device and method of cardiovascular property

Technical field

The device and method consistent with exemplary embodiment are related to the extraction of cardiovascular property.

Background technology

Pulse wave analysis (PWA) and pulse wave velocity (PWM) method are commonly used in the case of without using pressure cuff Non-invasively extract cardiovascular property.PWA methods are by analyzing peripheral part (for example, finger tip, radial artery etc.) from body Photoplethysmogram (PPG) signal or the shape of body surface pressure signal extract the method for cardiovascular property.From left ventricle The blood of discharge causes reflection, and reflections affect is around body in the region of big branch (such as, the arteria renalis, common iliac artery) The pulse wave or the shape of body pressure wave that part measures.Therefore, by analyzing this shape, deducibility arterial stiffness, artery Age, aortic pressure waveform etc..PWV methods are to extract the method for cardiovascular property by measuring pulse wave transmission time. According to this method, electrocardiogram (ECG) signal and PPG signals of peripheral part by measuring body simultaneously pass through the near of arm The speed of peripheral part of the blood arrival body from heart is calculated like length divided by PPT to measure R- peak values (the left heart of ECG Room shrink interval) and finger or radial artery PPG signals or pressure pulse wave peak value between delay (pulse propagation time (PTT))。

In general, in order to measure ECG, it necessarily is formed as the measurement position 1 of heart and measurement position 2 through body surface Closed loop, wherein, heart is located at the center of closed loop, therefore, the right hand and left hand should contact measurement system simultaneously electrode or system Electrode should with a point contact of the skin surface of the trunk or chest in heart side and also with the opposite side in heart Another point contact.Therefore, using personal wearable device come to measure ECG be very difficult.

Invention content

Technical problem

Provide a kind of equipment and side for being used to not have in bandage to extract cardiovascular property in the case of particular sensor Method.

Technical solution

The content of present invention is provided to introduce the structure further described in the following detailed description in simplified form The selection of think of.The content of present invention is not intended to the key feature and essential feature of the claimed theme of mark, the content of present invention It is not intended to the range for assisting in claimed theme.

One side accoding to exemplary embodiment provides a kind of equipment for extracting cardiovascular property, the equipment packet It includes：First sensor is configured as measuring by the vibration signal of the pulse wave generation of object；Second sensor is configured as surveying Measure the pulse wave signal of object；Processor is configured as vibration signal and pulse wave signal based on measurement to perform based on Calculate the operation of cardiovascular property；Main body, installation first sensor, second sensor and processor.

The equipment may also include：An at least bandage is connected to main body and passes through tension by main body fixed to wrist.

First sensor can generate arteries and veins in the state of wrist is surrounded by tension in an at least bandage at radial artery Fight wave when, measure and the vibration of main body be transmitted to by an at least bandage.

First sensor may include：Piezoelectric transducer is configured as measuring the vibration of the pulse wave transmitted by main body.

First sensor may include：Force snesor or effector are configured as measuring connecing for the object that is transmitted by main body Touch pressure.

First sensor may include：Piezoelectric bender is configured as generating electric signal according to the deformation of piezoelectric bender； Rigid support is installed in main body, is propped up to be formed in the state of cavity between rigid support and piezoelectric bender Support the both ends of piezoelectric bender；Pressurizing block, is configured as receiving the vibration of pulse wave, and pressurizes to piezoelectric bender, from And deform piezoelectric bender.

First sensor may include：Piezoelectric bender is configured as generating electric signal according to the deformation of piezoelectric bender； Rigid support is installed in main body, is propped up to be formed in the state of cavity between rigid support and piezoelectric bender Support the both ends of piezoelectric bender；Force snesor is configured as measuring the contact of the object transmitted by main body, receives pulse The vibration of wave, and pressurize to piezoelectric bender, so as to deform piezoelectric bender.

Main body may include housing, and housing receivable second sensor so that second sensor is exposed to object.

The equipment may include：Second sensor is connected to housing by telescopic connecting component.

Housing receivable first sensor so that compared to close to processor, first sensor is closer to second sensor.

Second sensor may include：Sensor board；Light source is installed on sensor board to emit light into object；Inspection Device is surveyed, is installed on sensor board to detect the light returned from object.

Light source can be one selected from light emitting diode (LED), laser diode and fluorophor.

Processor may include：Delay time calculator, be configured as calculating the vibration signal and the pulse wave signal that measure it Between delay time；Cardiovascular property extractor is configured as the delay time extraction cardiovascular property based on calculating.

Processor may also include：Characteristic point extractor is configured as from each carrying in vibration signal and pulse wave signal At least one of peak point, valley point, greatest gradient point and minimum slope point is taken to be used as characteristic point；Delay time calculator, Carry out the computing relay time using the characteristic point of extraction.

The equipment may also include：Communicator is installed in main body and is configured as vibration signal, pulse wave letter Number, characteristic point, delay time, at least one of pulse wave velocity (PWV) and cardiovascular property be sent to external device (ED).

Cardiovascular property may include：Blood pressure, blood vessel age, arterial stiffness, aortic pressure waveform, pressure index and fatigue At least one of degree.

The equipment may also include：Display is configured as under the control of a processor putting forward the cardiovascular property of extraction Supply user.

Processor may include：Preprocessor, be configured as to by first sensor and second sensor measurement signal into Row pretreatment；Signal adapter is configured as performing analog-to-digital conversion to the signal of measurement.

One side according to another exemplary embodiment provides a kind of equipment for extracting cardiovascular property, described to set It is standby to include：Main body；An at least bandage is connected to main body and is configured around the wrist of object；First sensor is mounted In main body and including force snesor or effector, wherein, force snesor or effector are configured as：When generating pulse wave, Measure the contact signal of object generated by the vibration that main body is transmitted to by an at least bandage；Second sensing Device is installed in main body and is configured as the pulse wave signal of measurement object；Processor is installed in main body and is configured To perform the operation for extracting cardiovascular property based on contact signal and pulse wave signal.

Contact Signal separator can be exchange (AC) component signal and direct current (DC) component signal by processor.

Processor can calculate the delay time between AC component signals and pulse wave signal and the delay time based on calculating To extract cardiovascular property.

Processor can collect the information of the contact condition about force snesor based on DC component signals, and based on being collected into Information come determine extraction cardiovascular property.

Processor can be corrected the value of the cardiovascular property of extraction or be represented cardiovascular property with prolonging based on DC component signals The estimation model of relationship between the slow time.

One side according to another exemplary embodiment provides a kind of equipment for extracting cardiovascular property, described to set It is standby to include：Main body；An at least bandage is connected to main body and is configured around the wrist of object；First sensor is mounted In main body and including microphone, wherein, microphone is configured as：When generating pulse wave, measure by by described at least one Root bandage is transmitted to the acoustic signals that the vibration of main body generates；Second sensor is installed in main body and is configured as measuring The pulse wave signal of object；Processor is installed in main body and is configured as being held based on acoustic signals and pulse wave signal Row extracts relevant operation with cardiovascular property.

Microphone may include at least one of electret microphone and MEMS (MEMS) microphone.

First sensor may also include：Diaphragm is configured as that shaking for main body will be sent to by an at least bandage Dynamic signal is converted to acoustic signals and acoustic signals is sent to microphone.

One side according to another exemplary embodiment provides a kind of by including being equipped with first sensor and the second biography The cardiovascular property extraction equipment of the main body of sensor extracts the method for cardiovascular property, the method includes：In the first sensing The vibration signal generated by the pulse wave of object is measured at device；Pulse wave signal is measured at second sensor；Believed based on vibration Number and pulse wave signal perform and extract relevant operation with cardiovascular property.

The step of measuring vibration signal may include：When at least bandage for being connected to main body around object wrist simultaneously Will by tension by main body be fixed to wrist in the state of generate pulse wave when, measure pass through described in an at least bandage be transmitted to The vibration signal of main body.

The step of performing operation may include：Calculate the delay time between vibration signal and pulse wave signal and based on calculating Delay time extract cardiovascular property.

The step of performing operation may include：From in vibration signal and pulse wave signal each extraction peak point, valley point, At least one of greatest gradient point and minimum slope point are used as characteristic point, and the step of computing relay time may include：Make With the characteristic point of extraction come the computing relay time.

The method may also include：The cardiovascular property of extraction is supplied to by user by display.

From following specific embodiment, drawings and claims, other example features and aspect will be apparent.

Advantageous effect

In the case of can not there is no particular sensor in bandage, cardiovascular property is extracted.

Description of the drawings

By the way that the detailed description of exemplary embodiment, above and/or other illustrative aspects will become below in conjunction with the accompanying drawings It must understand and be easier to understand, wherein：

Fig. 1 is the schematic the overall diagram for being used to extract the equipment of cardiovascular property according to exemplary implementation.

Fig. 2 is the block diagram for being used to extract the equipment of cardiovascular property shown accoding to exemplary embodiment.

Fig. 3 is the block diagram of the exemplary embodiment of the configuration for the processor for being shown specifically Fig. 2.

Fig. 4 A to Fig. 4 C be for describe for extract cardiovascular property equipment signal processing step curve graph.

Fig. 5 is the block diagram for being used to extract the equipment of cardiovascular property shown accoding to exemplary embodiment.

Fig. 6 A are the diagrams for being used to extract the main body of the equipment of cardiovascular property shown accoding to exemplary embodiment.

Fig. 6 B be for describe for extract cardiovascular property equipment first sensor diagram.

Fig. 7 is to show showing for extracting the configuration of the main body of the equipment of cardiovascular property accoding to exemplary embodiment Figure.

Fig. 8 A and Fig. 8 B is to show matching for extracting the main body of the equipment of cardiovascular property accoding to exemplary embodiment The diagram put.

Fig. 9 is for describing the diagram for being used to extract the equipment of cardiovascular property accoding to exemplary embodiment.

Figure 10 is the flow chart for the method for showing extraction cardiovascular property accoding to exemplary embodiment.

Figure 11 be show accoding to exemplary embodiment execution extraction cardiovascular property method with cardiovascular property phase The detail flowchart of the step of operation of pass.

Through the drawings and specific embodiments, unless otherwise described, otherwise identical drawing reference numeral will be understood to refer to Identical element, feature and structure.For clear, description and convenience, the relative size of these elements and description may be exaggerated.

Specific embodiment

There is provided the following detailed description, with help reader obtain to method described here, equipment and/or system it is comprehensive Understand.Various changes, modification and the equivalent of system described here, equipment and/or method will may be suggested to the general of this field Logical technical staff.In the following description, when the known function and the detailed description of configuration included herein is with unnecessary thin When section obscures theme, it will be omitted.

It will be understood that although first, second grade of term can be used for describing various elements herein, these elements should not be by this A little term limitations.These terms are only used to distinguish an element with another element.In addition, unless context clearly separately has Instruction, otherwise singulative is also intended to including plural form.In the description, unless clearly opposite describe, otherwise word " wraps Include " and its modification will be understood as implying the element for including describing, but be not excluded for any other element.Such as " ... unit " and The term of " module " represents to handle the unit of at least one functions or operations, and they can be by using hardware, software or hard The combination of part and software is realized.

Hereinafter, will be described in detail with reference to the accompanying drawings for extract cardiovascular property device and method exemplary embodiment.

With reference to Fig. 1, the equipment 1 for being used to extract cardiovascular property accoding to exemplary embodiment can be wearable in wrist On wearable device.As shown in FIG., equipment 1 includes main body 100 and is connected to the bandage 121 and 122 of main body 100, In, bandage 121 and 122 is flexible, so as to can be surrounded and be maintained in the wrist of object by tension, so as to lead Body is fixed to wrist.

In addition, display 110 and operator 115 may be mounted to that in the main body 100 of equipment 1.

Display 110 can be shown with the relevant various information of cardiovascular property (for example, cardiovascular property information (such as, blood Pressure, blood vessel age, arterial stiffness, aortic pressure waveform, pressure index and fatigue strength), for extracting each of cardiovascular property Kind of sensor signal, the analysis information of sensor signal and additional information (such as, according to the warning of the cardiovascular property of extraction and Alarm)), so as to which this information is supplied to user.In this case, various scheduled visions can be used in display 110 And/or any method in non-vision method provides information to user.For example, if the blood pressure of extraction corresponds to danger etc. Grade, the then blood pressure extracted can be with red displays or if the blood pressure of extraction corresponds to normal level, and the blood pressure extracted can To be shown with green.

Meanwhile display 110 can be equipped with touch-input function and exportable user interface so that user can be used Touch-input function inputs any order in various orders, so as to can perform necessary operation.

Operator 115 can receive the control command of user and send commands to processor 220, and may include being used for Input opens and closes the power knob of the order of the power supply of equipment 1.

In addition, as shown in Figure 2, according to illustrative aspect, main body 200 can also comprise sensor 210 and processor 220。

Sensor 210 measures to extract the sensor signal needed for cardiovascular property.As shown in Figure 2, sensor 210 It may include first sensor 211 and second sensor 212.

First sensor 211 is measured by the first signal of the pulse wave generation of object.For example, when logical in bandage 121 and 122 Mechanical oscillation during generation pulse wave, are transmitted to by overtension in the state of surrounding wrist at radial artery by bandage 121 and 122 Main body 100.In this case, first sensor 211 can measure the vibration letter that main body 100 is sent to by bandage 121 and 122 Number the first signal of conduct.

First sensor 211 includes measuring the radial artery pulse wave for being transmitted to main body 100 by bandage 121 and 122 Vibration sensor element, and sensor element may include with the piezoelectric property that mechanical oscillation are converted to electric signal Piezoelectric transducer.For example, piezoelectric bender can be used to realize in first sensor 211, wherein, which is according to plate Mechanically deform generate potential plate piezoelectric transducer or first sensor 211 can pass through the series connection of multiple piezoelectric benders And/or it is connected in parallel to realize.In this case, piezoelectric transducer may include piezoelectric ceramics (such as, lead zirconate titanate (PZT)) Or piezopolymer (such as, polyvinylidene fluoride (PVDF)).However, the disclosure is not limiting, and the first sensing Device 211 may include to measure any sensor in various types of sensors of the mechanical oscillation of pulse wave.

Second sensor 212 is measured by the second signal of the pulse wave generation of object.For example, second sensor 212 can lead to It crosses and emits light into the light that object and detecting returned from object to measure pulse wave signal as second signal.Second sensor 212 may be formed at so that the region at the back side with wrist is in close contact in main body 100, and can measure from capillary or vein The pulse wave signal that blood vessel generates.For example, second sensor 212 may include light source for emitting light into object and be used for The detector of pulse wave signal is measured by detecting the light returned from object, wherein, light source and detector are for measuring arteries and veins It fights the sensor element of wave signal.In this case, light source may include：Light emitting diode (LED), laser diode or fluorescence Body, but not limited to this.

Simultaneously, if it is desired, first sensor 211 and second sensor 212 may each comprise for in wrist area Blood vessel matches and improves the array of multiple sensor elements of signal quality.

Processor 220 can receive measured the first signal and the second signal, and using the first received signal and Second signal performs any operation in the relevant various operations of extraction with cardiovascular property.

Fig. 3 is the block diagram of the exemplary embodiment of the configuration for the processor for being shown specifically Fig. 2.Fig. 4 A to Fig. 4 C are for retouching State for extract cardiovascular property equipment signal processing step curve graph.

As shown in Figure 3, processor 220 includes preprocessor 221, signal adapter 222, characteristic point extractor 223, prolongs Slow time calculator 224 and cardiovascular property extractor 225.

When preprocessor 221 receives the first signal and the second signal from first sensor 211 and second sensor 212 respectively When, preprocessor 221 performs the signal received pretreatment (such as, noise remove, signal amplification etc.).For example, pretreatment The executable pretreatment of device 221 (such as, signal normalization, for trend and offset removal go trend, signal smoothing and use Low-pass filter removes high-frequency noise).

In the case where the first signal and the second signal of measurement are analog signal, signal adapter 222 can turn signal It is changed to digital signal.

Fig. 4 A are shown by measuring to the first signal 411 measured by first sensor 211 and by second sensor 212 The waveform of signal that second signal 412 carries out analog-to-digital conversion with 1000Hz and pre-processed and obtained to the signal of conversion.

Characteristic point extractor 223 extracts characteristic point to obtain the first signal 411 and second signal 421 as shown in Figure 4 A Between delay time.Make for example, characteristic point extractor 223 can extract significant point from the first signal 411 and second signal 412 It is characterized a little, and can be as shown in Figure 4 B by using the characteristic point of extraction or by assemblage characteristic point come in 411 He of signal Make marks M1 and M2 in each in signal 412.In this case, characteristic point may include the first signal 411 and the second letter Numbers 412 peak point, valley point and/or greatest gradient point and minimum slope point, but exemplary embodiment is without being limited thereto.Fig. 4 B The maximum of points of the first signal of flag activation 411 and the positive slope of second signal 412 is as characteristic point.

Delay time calculator 224 can calculate the characteristic point M1 marked on the first signal 411 with being marked in second signal 412 Characteristic point M2 between delay time.The pulsation of delay time instruction radial artery is applied to the when that the back side of wrist spent Between.Due to being the mechanical oscillation signal generated by the pulse wave of radial artery by the first signal that first sensor 211 measures And the second signal (for example, pulse wave signal) measured by second sensor 212 is in the main blood by wrist and hand The arterial blood of pipe is applied to the pulse wave signal measured after pulse wave signal, so the machine measured by first sensor 211 Delay time between tool vibration signal and the pulse wave signal measured by second sensor 212, which can be assumed to be, to be had and body Peripheral part local pulse wave velocity (PWV) the similar characteristic of characteristic.

Cardiovascular property extractor 225 can obtain specific mould based on the delay time between the first signal and second signal Formula, wherein, can the computing relay time be continued by delay time calculator 224.In addition, cardiovascular property extractor 225 can Cardiovascular property is extracted based on the delay time of acquisition.In this case, cardiovascular property may include：Blood pressure, blood vessel year Age, artery sclerosis, aortic pressure waveform, pressure index and fatigue strength, but not limited to this.

The lower part of Fig. 4 C illustrates that the curve graph of the delay time between the first signal of lasting acquisition and second signal, And the top of Fig. 4 C illustrates that the systolic pressure by holding one's breath or when isometric practice causes with the interval of a few minutes blood pressure change Curve graph.With reference to Fig. 4 C, it can be seen that systolic pressure and the pattern obtained from the delay time between the first signal and the second signal Between there are correlations.

Cardiovascular property extractor 225 can generate the delay time represented between systolic pressure and the first signal and the second signal Between correlation correlation model.In this case, correlation model can be with for example, can believe from the first signal and second Average delay time between number infers that the form of the mathematical algorithm of blood pressure generates, and but not limited to this, and correlation model can It is stored in storage device in the form of matching list.In this case, storage device may include：It is flash memory, hard disk, miniature more Media card, card-type memory (for example, SD or XD memories), random access memory (RAM), static RAM (SRAM), read-only memory (ROM), electrically erasable programmable read-only memory (EEPROM), programmable read only memory (PROM), magnetic memory, disk or CD, but not limited to this.

For example, cardiovascular property extractor 225, which can be directed to predetermined amount of time, measures and collects the first signal and the second signal As learning data, then the delay time between the first signal and second signal is calculated using the learning data of collection.This Outside, cardiovascular property extractor 225 can measure by hold one's breath within a predetermined period of time or isometric practice caused by systolic pressure, then Blood pressure estimation formulas is generated as the related of the correlation represented between systolic pressure and the delay time calculated using learning data Model.

With reference to Fig. 5, in the main body 500 of equipment 1 other than sensor unit 210 and processor 220, communicator is further included 510。

As described above, sensor unit 210 includes first sensor 211 and second sensor 212, wherein, the first sensing Device 211 is measured by the vibration signal that the pulse wave in radial artery generates as the first signal, and second sensor 212 measures wrist The capillary on top or the pulse wave signal of vein blood vessel, wherein, pass through the Major Vessels in wrist and hand from radial artery Arterial blood is applied to pulse wave signal.

Processor 220 uses the first signal and the second letter measured respectively by first sensor 211 and second sensor 212 Number handle any operation in various operations.Processor 220 can control communicator 510 to be connected to external device (ED) 550, and can By cooperating to handle any operation in various operations with the external device (ED) 550 connecting.Processor 220 can will be according to associated The desired information of degree that relevant function is extracted with cardiovascular property provisioned in external device (ED) 500 is supplied to external device (ED) 500.For example, information may include：The first signal and the second signal of measurement, the signal of pretreatment, the delay time calculated, PWV, The cardiovascular property information of correlation model, the characteristic point of extraction and/or extraction.

Communicator 510 can access communication network under the control of processor 220 by using the communication technology, and can be with The external device (ED) 550 for accessing same communication network connects, so as to send and receive required data.The communication technology may include： It is Bluetooth communication, bluetooth low energy (BLE) communication, near-field communication (NFC), WLAN (WLAN) communication, ZigBee communication, red Outer data association (IrDA) communication, ultra wide band (UWB) communication, Ant+ communications, Wi-Fi communications, is penetrated at Wi-Fi direct (WFD) communication Frequency identification (RFID) communication, 3G communications, 4G communications, 5G communications etc., but not limited to this.

For example, when extracting cardiovascular property based on the first signal and the second signal, processor 220 can pass through communicator The cardiovascular property of extraction is sent to external device (ED) 550 by 510 so that passes through the interface module being equipped in external device (ED) 550 Cardiovascular property is supplied to user by (for example, loud speaker, display, haptic device etc.).External device (ED) 550 can be relative to For extracting mobile terminal of the equipment 1 of cardiovascular property with excellent calculated performance, (such as, smart phone or tablet are personal Computer (PC)), but not limited to this, and external device (ED) 550 may include various types of information provider unit (such as, platforms Formula PC, notebook PC etc.) in any device.

In another example, when external device (ED) 550 has relatively excellent calculated performance, and is provided as having using biography When sensor signal extracts the function of cardiovascular property, communicator 510 can will be by first sensor under the control of processor 220 211 the first signals measured and external device (ED) 550 is sent to by the second signal that second sensor 212 measures to allow external fill Put the extraction of 550 execution cardiovascular properties.External device (ED) 550 can be equipped with as the device with cardiovascular property abstraction function (such as, smart phone, tablet PC, Desktop PC, notebook PC, server etc.).When external device (ED) 550 is received from communicator 510 During to sensor signal, external device (ED) 550 can extract cardiovascular property and the interface module by being equipped in external device (ED) 550 Cardiovascular property is supplied to user.In addition, when receiving cardiovascular property information from external device (ED) 550 by communicator 510 When, processor 220 can provide information to user by display.

In another example, when processor 220 calculates the delay time between the first signal and second signal and will delay When temporal information is supplied to external device (ED) 550, external device (ED) 550 can be used correlation model and can be used by external device (ED) 550 Cardiovascular property (such as, the blood pressure of user) is extracted using the correlation model of delay time management received.

However, cooperating between equipment 1 and external device (ED) 550 is not limited to above example.

Fig. 6 A are the diagrams for being used to extract the main body of the equipment of cardiovascular property shown accoding to exemplary embodiment.Fig. 6 B Be for describe for extract cardiovascular property equipment first sensor diagram.

With reference to Fig. 6 A, including for the main body 600 of equipment 1 of extracting cardiovascular property accoding to exemplary embodiment：The One sensor 610, second sensor 620, mainboard 630, display 640 and housing 650.

First display 610 is installed in housing 650.Housing 650 accommodate first sensor 610 so that compared to by The mainboard 630 of nearly installation process device, first sensor 610 are opposite closer to second sensor 620.

First sensor 610 may include piezoelectric bender 611, wherein, piezoelectric bender 611 is according to being applied to flexural piezoelectric The pressure of device 611 and mechanically deform, and according to deformation generate electric signal.Piezoelectric bender 611 can be as shown in FIG. Two or more stack layers array.In this case, piezoelectric bender 611 can be with the biography of second sensor 620 Sensor plate 623 is electrically connected, and may be sent to that sensor board 623 is used as first by the electric signal that piezoelectric bender 611 generates Signal.However, example embodiment is not limited to above description so that piezoelectric bender 611 can be electrically connected with mainboard 640, and Generated electric signal can be sent straight to mainboard.

First sensor 610 may also include the pressurizing block 612 for the mechanically deform for generating piezoelectric bender 611.In this feelings Under condition, pressurizing block 612 can have the side being in close contact with sensor board 623, and have and closely connect with piezoelectric bender 611 Tactile opposite side.When being passed to main body 600 by the tension (2) of bandage by the mechanical oscillation that radial artery pulse wave (1) generates And and then sensor board 623, when moving (3), pressurizing block 610 can be according to the movement of sensor board 623 to piezoelectric bender 611 are pressurizeed and so that piezoelectric bender 611 deforms.Pressurizing block 612 can be formed by rigid material.

In addition, first sensor 610 may also include rigid support 613, wherein, rigid support 613 is by rigid material It is formed between rigid support 613 and piezoelectric bender 611 and supports piezoelectric bender 611 in the state of formation cavity 615 Both ends.

Second sensor 620 is installed in housing 650 to be exposed to object (that is, back side of the hand of user).Second Sensor 620 includes light source 621 and detector 622, wherein, light source 621 is installed on sensor board 623 to connect with object It touches and emits light to object, and detector 622 is installed on sensor board 623 to detect the light returned from object.

In addition, second sensor 620 may also include with the sensor board 623 at both ends being connect with housing 650.Sensor The connecting component 625 arranged between plate 623 and housing 650 can be telescopic.It will be generated when by bandage 680 by radial artery Mechanical oscillation when being transmitted to the housing 650 of main body 600, the telescopic connecting component 625 of housing 650 receives mechanical oscillation simultaneously The movement of sensor board 623 is generated, and as a result, as described above, the pressurizing block 612 of first sensor 610 makes piezoelectricity curved Bent device 611 deforms.

Sensor board 623 is electrically connected with light source 621 and detector 622, so as to which the control signal of processor is sent to light Source 621 simultaneously receives the second signal measured from detector 622.

Mainboard 630 can be supported by lid 651 and can include display 640 on a surface of mainboard 630, will be various Information is supplied to user.In addition, above-mentioned processor 220 can be mounted on mainboard 630, and processor 220 can be based on passing through The first signal and the second signal that the element 631 being electrically connected with sensor board 623 receives are extracted to perform for cardiovascular property The various operations needed.

Fig. 7 is to show showing for extracting the configuration of the main body of the equipment of cardiovascular property accoding to exemplary embodiment Figure.Configuration according to the embodiment of Fig. 7 is the exemplary embodiment for the first sensor for having modified Fig. 6 A.

With reference to Fig. 7, the configuration of main body includes：First sensor 710, second sensor 620, mainboard 630, display 640 With housing 650.To the feature different from the feature discussed above for Fig. 6 A be described.

First sensor 710 is installed in position in housing 650 so that compared to the mainboard close to installation process device 630, first sensor 710 is closer to second sensor 620.First sensor 710 includes piezoelectric bender 611, wherein, piezoelectricity Bending apparatus 611 according to press deforms and generates electric signal according to deformation.In this case, piezoelectric bender 611 can Be as illustrated in the drawing two or more stack layers array.Piezoelectric bender 611 can be with the biography of second sensor 620 Sensor plate 623 is electrically connected, and the electric signal generated in piezoelectric bender 611 is sent to sensor board 623.However, this is not It is restricted, and optionally, piezoelectric bender 611 can be electrically connected with mainboard 640, and the electric signal generated can be direct It is sent to mainboard 640.

In addition, different from the embodiment of Fig. 6 A, first sensor 710 may include force snesor.However, this is not restricted , and first sensor 710 may include any sensing in the sensor for measuring various other types of contact Device, such as, effector.Force snesor 711 is formed to be in close contact with the bottom of sensor board 623, and measures and pass through master The contact signal for the object that body 700 is sent.In addition, the arteries and veins that force snesor 711 is occurred by bandage reception in radial artery It fights the vibration of wave, and is pressurizeed to piezoelectric bender 611 and deform piezoelectric bender 611.Therefore, according to exemplary implementation Example can form pressing element 710, to pressurize to piezoelectric bender 611 in the lower part of force snesor 711.

The contact signal measured by force snesor 711 is with the vibration signal that is measured by piezoelectric bender 611 by together It is sent to sensor board 623 and is used as the first signal, and the element by connecting sensor board 623 and mainboard 630 is sent to Mainboard 630.

In addition, first sensor 710 may also include rigid support 613, wherein, rigid support 613 is by rigid material It is formed between rigid support 613 and piezoelectric bender 611 and supports piezoelectric bender 611 in the state of formation cavity 615 Both ends.

The processor 220 formed on mainboard 630 can be received based on the element 631 by being electrically connected with sensor board 623 The first signal and the second signal come perform extraction cardiovascular property needed for various operations in any operation.For example, processing Device 220 can be based on the vibration signal as the first signal and as second signal pulse wave signal come the computing relay time and The delay time of calculating can be used to extract cardiovascular property.In addition, reflection can be used to be applied to skin by sensor for processor 220 Direct current (DC) component of first signal of the pressure on skin as contact signal come monitor hemoperfusion, capillary it is suitable Answering property etc..

Second sensor 620 is installed in be exposed to the back side of the hand of user in housing 650, and including being mounted on Light source 621 and detector 622 on sensor board 623.It is connect in addition, second sensor 620 may also include to have with housing 650 Both ends sensor board 623, and the telescopic mechanical oscillation will be generated by the pulse wave of radial artery can be formed It is effectively transmitted to force snesor 711.

Fig. 8 A and Fig. 8 B is to show matching for extracting the main body of the equipment of cardiovascular property accoding to exemplary embodiment The diagram put.Configuration according to the main body of the embodiment of Fig. 8 A and Fig. 8 B is the exemplary reality for the first sensor for having modified Fig. 7 Apply example.

With reference to Fig. 8 A and Fig. 8 B, first sensor 810 can be by omitting piezoelectric bender from the first sensor 710 of Fig. 7 A 611 realize.For example, as shown in Figure 8 A, first sensor 810 may include force snesor 811 and rigid support 813, In, force snesor 811 has appropriate sensitivity, and rigid support 813 is between force snesor 811 and rigid support 813 The pressurization of the pressing element of support force snesor 811 in the state of formation cavity 615.Force snesor 811 is only exemplary, and It is without being limited thereto for measuring the sensor of contact.Force snesor 811 may include to measure the other types of contact Sensor in any sensor, such as, effector.

As described above, when the mechanical oscillation by the generation of the pulse wave of radial artery be sent to main body 800 (in particular, The sensor board 623 of second sensor) when, the force snesor 811 formed on the bottom of sensor board 623 can will be used as first The contact of signal is sent to sensor board 623, wherein, contact signal is in pressing element 812 to rigid support 813 It generates under pressure.

When the processor 220 in main board 630 receives the contact signal as the first signal, processor The first Signal separator received can be AC component signals and DC component signals by 220.In addition, separation can be used in processor 220 AC component signals and calculate between two signals as the pulse wave signal of the second signal measured by second sensor 620 Delay time, and can cardiovascular property be extracted based on the delay time of calculating.

In addition, processor 220 can collect the contact condition about force snesor by using the DC component signals of separation Information, wherein, the contact condition of force snesor includes the contact being applied to by force snesor 811 on object.Processing Device can be then based on the information collected to determine extraction cardiovascular property or remeasure extraction using the signal of measurement Signal, and can determine correction extraction cardiovascular property or correction cardiovascular property needed for estimation model.

For example, due to the thickness for the wrist for wearing main body 800 or due to wearing position caused by wearing position, movement etc. Change, so main body 800 may not be positioned at accurate test point.In this case, processor 220 is comparable logical It crosses force snesor 811 and is applied to the contact of object and preset threshold value.If contact is greater than or equal to threshold value, locate The signal measured by first sensor 810 and second sensor 620 can be used to be extracted to perform cardiovascular property for reason device 220, Otherwise processor 220 can determine that the signal of measurement is inaccurate and first sensor 810 and second sensor 620 is controlled to remeasure Signal.

Further, since the contact generated by pressure sensor 811 can influence the suitable of hemoperfusion and capillary One or more of answering property, so processor 220 calculates contact based on DC components, and by will be according to calculating The knots modification for contacting the hemoperfusion of blood pressure or the compliance of capillary is applied to the cardiovascular property value of estimation or for table Show the estimation model of relationship between delay time and cardiovascular property to calibrate the cardiovascular property value of estimation or estimation model.Estimate Count the mathematical formulae or delay time and cardiovascular property value that model can be the cardiovascular property determined based on delay time Mapping table mapped onto one another, but not limited to this.

In addition, with reference to Fig. 8 B, according to this exemplary embodiment, rigid support 813 can be from the first sensor of Fig. 8 A 810 omit.Therefore, according to the exemplary embodiment of Fig. 8 B, support the lower support member of the housing 650 of first sensor 810 can It is formed by rigid material, and the force snesor 811 of first sensor 810 can pressurize to the lower support member of housing 650 And measure contact signal.Therefore, the volume of main body configuration can be reduced.

Include the first sensor of Fig. 6 A according to the equipment for being used to extract cardiovascular property of this exemplary embodiment Modification.Assuming that the basic configuration of the main body 900 in addition to first sensor is identical with the embodiment of Fig. 6 A.

With reference to Fig. 9, the first sensor in main body 900 includes microphone 910.Microphone 910 can measure the machinery passed through Vibrate generate acoustic signals (3), wherein, when in radial artery generate pulse wave (1) when mechanical oscillation pass through bandage 680 (2) It is sent to main body 900.The acoustical signal measured by microphone 910 can be used as the first signal and be sent to processor.For example, wheat Gram wind 910 may include：Electret microphone, MEMS (MEMS) microphone etc., but not limited to this.

In addition, first sensor can also include diaphragm so that the machinery transmitted by the tension of bandage is shaken in its front end Dynamic signal is converted to acoustic signals, and acoustic signals are sent to microphone 910.

In this case, processor 220 can calculate the acoustic signals for being measured and being sent by microphone 910 with being passed by second Delay time between the pulse wave signal that sensor measures, and delay time extraction cardiovascular property can be used.

It has described with reference to Fig. 6 A to Fig. 9 and has been repaiied for extracting the various of configuration of main body of the equipment 1 of cardiovascular property The embodiment changed.However, these are only exemplary, therefore, it is not limited to the above embodiments in terms of the disclosure, and can be into Row various modifications as skilled in the art will appreciate.

Figure 10 is the flow chart for the method for showing extraction cardiovascular property accoding to exemplary embodiment.Figure 11 is to show root According to exemplary embodiment execution extraction cardiovascular property method operation relevant with cardiovascular property the step of it is detailed Flow chart.

According to the exemplary embodiment of Figure 10, as shown in 1010, for extract the equipment 1 of cardiovascular property by using First sensor come measure by object pulse wave generation the first signal.For example, when the bandage in equipment 1 is surrounded by tension When generating pulse wave in the state of wrist at radial artery and mechanical oscillation being transmitted to main body by bandage, equipment 1 can Vibration signal is measured as the first signal.For example, first sensor may include carrying out deformation according to mechanical oscillation and generate telecommunications Number piezoelectric transducer, such as, piezoelectric bender.

As shown in 1020, equipment 1 is measured by using second sensor by the second letter of the pulse wave generation of object Number.For example, second sensor may be formed at so that the region at the back side with wrist is in close contact in main body, and can be by by light It is emitted to the top of wrist and detects the light returned from the top of wrist and produced come the capillary or vein blood vessel measured from wrist Raw pulse wave signal.

Then, as shown in 1030, equipment 1 extracts phase to perform using the first signal and the second signal with cardiovascular property The various operations closed.

Operation 1030 will be described in detail with reference to Figure 11.As shown in 1031, first, from first sensor and second sensor The first signal and the second signal are received respectively.In this case, as needed, the first signal and the second signal can be performed pre- Processing (such as, removing trend, signal smoothing and the removal high-frequency noise using low-pass filter) and analog-to-digital conversion.

As shown in 1032, from each extraction characteristic point in each or preprocessed signal in the signal received.It is special Sign point can be the significant point for calculating in two signals of the delay time between two signals, and may include for example Peak point, valley point and the greatest gradient point and minimum slope point of the first signal and the second signal, but not limited to this.

Then, as shown in 1033, when being extracted characteristic point from each in signal, characteristic point is used to calculate the first letter Delay time number between second signal.Delay time be the pulsation of radial artery be applied to that the back side of wrist spent when Between, and can be the factor of the local PWV of the peripheral part for reflecting body.

Later, as shown in 1034, the cardiovascular property of user is extracted using the delay time of calculating.It can be used advance The correlation model of generation extracts the delay time corresponding cardiovascular property with calculating.In this case, correlation model can With to represent the form quilt of the mathematical formulae of the correlation between delay time and cardiovascular property (such as, blood pressure) or matching list It generates in advance.

As shown in 1035, the cardiovascular property of extraction is supplied to by user by display.The cardiovascular property of extraction User can be supplied in any method in various scheduled visions and/or non-vision method.For example, blood pressure information can basis User or usually standard applicatory are provided with the corresponding color of the range of the blood pressure with extraction.It in addition, can be according to extraction The value of cardiovascular property shows appropriate guidance information or warning message.

Current exemplary embodiment can be implemented as the computer-readable code in computer readable recording medium storing program for performing.It forms The code and code segment of computer program can easily be inferred by this field computer programmer.Computer readable recording medium storing program for performing All types of nonvolatile recording mediums including storing mechanized data.The example packet of computer readable recording medium storing program for performing It includes：ROM, RAM, CD-ROM, tape, floppy disk and optical data memories.In addition, computer readable recording medium storing program for performing can be distributed in net Computer system on network, wherein, computer-readable code can store and execute in a distributed fashion.

Many examples are described above.It is to be appreciated, however, that it can carry out various modifications.If for example, technology of description It is executed in different order and/or if the component in system, framework, device or the circuit described combines in different ways And/or replaced or supplemented by other assemblies or their equivalent, then appropriate result can be achieved.Therefore, other embodiment Within the scope of the claims.

Claims

1. a kind of equipment for extracting cardiovascular property, the equipment includes：

Main body, first sensor are mounted to main body, and second sensor is mounted to main body and processor is mounted to main body, Wherein：

First sensor is configured as measuring by the vibration signal of the pulse wave generation of object；

Second sensor is configured as the pulse wave signal of measurement object；

Processor is configured as vibration signal based on measurement and pulse wave signal to calculate cardiovascular property.

2. equipment according to claim 1, further includes：First bandage and the second bandage, are connected to main body, wherein, first Bandage and the second bandage are configured as main body being fixed to the wrist of object.

3. equipment according to claim 2, wherein, pulse is generated at radial artery in the state of wrist is surrounded in bandage During wave, first sensor measures the vibration that main body is transmitted to by bandage.

4. equipment according to claim 1, wherein, first sensor includes：Piezoelectric transducer is configured as measurement and passes through The vibration of the pulse wave of main body transmission.

5. equipment according to claim 4, wherein, first sensor includes：One in force snesor and effector, quilt It is configured to measure the contact of the object transmitted by main body.

6. equipment according to claim 1, wherein, first sensor includes：Piezoelectric bender is configured as according to piezoelectricity The deformation of bending apparatus generates electric signal；Rigid support is installed in main body, and in rigid support and piezoelectric bender Between formed cavity in the state of support piezoelectric bender both ends；Pressurizing block is configured as receiving the vibration of pulse wave, and right Piezoelectric bender pressurizes, so as to deform piezoelectric bender.

7. equipment according to claim 1, wherein, first sensor includes：Piezoelectric bender is configured as according to piezoelectricity The deformation of bending apparatus generates electric signal；Rigid support is installed in main body, and in rigid support and piezoelectric bender Between formed cavity in the state of support piezoelectric bender both ends；Force snesor is configured as measuring what is transmitted by main body The contact of object, and receive the vibration of pulse wave and pressurize to piezoelectric bender, so as to deform piezoelectric bender.

8. equipment according to claim 1, wherein, main body includes housing, and second sensor is installed in housing, So that second sensor is exposed to object.

9. equipment according to claim 8, further includes：Second sensor is connected to housing by telescopic connecting component.

10. equipment according to claim 8, wherein, compared to close to processor, first sensor be arranged to closer to Second sensor.

11. equipment according to claim 1, wherein, second sensor includes：Sensor board；Light source is installed in sensing On device plate and it is configured as emitting light into object；Detector is installed on sensor board and is configured as detection from object The light of return.

12. equipment according to claim 11, wherein, light source is in Light-emitting diode LED, laser diode and fluorophor One.

13. equipment according to claim 1, wherein, processor includes：Delay time calculator is configured as calculating and survey Delay time between the vibration signal and pulse wave signal of amount；Cardiovascular property extractor is configured as prolonging based on calculating Slow time extraction cardiovascular property.

14. equipment according to claim 13, wherein, processor further includes：Characteristic point extractor is configured as from vibration At least one of each extraction peak point, valley point, greatest gradient point and minimum slope point in signal and pulse wave signal As characteristic point；Delay time calculator, the characteristic point for being configured with extraction carry out the computing relay time.

15. equipment according to claim 14, further includes：Communicator is installed in main body and is configured as to vibrate At least one of signal, pulse wave signal, characteristic point, delay time, pulse wave velocity PWV and cardiovascular property are sent to outer Part device.

16. equipment according to claim 13, wherein, cardiovascular property includes：Blood pressure, blood vessel age, arterial stiffness, master At least one of arterial pressure waveform, pressure index and fatigue strength.

17. equipment according to claim 13, further includes：Display, wherein, processor is configured as control display will The cardiovascular property of extraction is supplied to user.

18. equipment according to claim 13, wherein, processor includes：Preprocessor is configured as to by the first sensing The signal that device and second sensor measure is pre-processed；Signal adapter, the modulus for being configured as performing the signal measured turn It changes.

19. a kind of equipment for extracting cardiovascular property, the equipment includes：

Main body；

An at least bandage is connected to main body and is configured around the wrist of object；

First sensor is mounted to main body and including one in force snesor and effector, wherein, force snesor and strain One in device is configured as：When generating pulse wave, measure by being transmitted to main body by an at least bandage Vibrate the contact signal of the object generated；

Second sensor is mounted to main body and is configured as the pulse wave signal of measurement object；

Processor is mounted to main body and is configured as calculating cardiovascular property based on contact signal and pulse wave signal.

20. equipment according to claim 19, wherein, contact Signal separator is exchange AC component signals by processor With direct current DC component signals.

21. equipment according to claim 20, wherein, processor calculates prolonging between AC component signals and pulse wave signal Slow time simultaneously extracts cardiovascular property based on the delay time of calculating.

22. equipment according to claim 21, wherein, processor collects connecing about force snesor based on DC component signals The information for the state of touching, and based on the information being collected into come determining extraction cardiovascular property.

23. equipment according to claim 21, wherein, it is special that processor corrects the angiocarpy of extraction based on DC component signals Property value and represent one in the estimation model of cardiovascular property and the relationship between delay time.

24. a kind of equipment for extracting cardiovascular property, the equipment includes：

Main body；

First sensor is mounted to main body and including being configured as：When generating pulse wave, measure by by described at least one Root bandage is transmitted to the microphone of acoustic signals that the vibration of main body generates；

Processor is mounted to main body and is configured as calculating cardiovascular property based on acoustic signals and pulse wave signal.

25. equipment according to claim 24, wherein, microphone includes：Electret microphone and micro-electromechanical system (MEMS) At least one of microphone.

26. the equipment according to requiring 24, wherein, first sensor further includes：Diaphragm, be configured as by by it is described at least The vibration signal that a piece bandage is sent to main body is converted to acoustic signals and acoustic signals is sent to microphone.

27. a kind of carried by including being equipped with the cardiovascular property extraction equipment of the main body of first sensor and second sensor The method for vessel properties of coring, the method includes：

First sensor measures the vibration signal generated by the pulse wave of object；

Second sensor measures pulse wave signal；

Cardiovascular property is calculated based on vibration signal and pulse wave signal.

28. according to the method for claim 27, wherein, measure vibration signal the step of include：When in an at least bandage Be connected to main body, around object wrist and main body is fixed to generate pulse wave in the state of wrist when, measure by described At least a bandage is transmitted to the vibration signal of main body.

29. according to the method for claim 27, wherein, calculate cardiovascular property the step of include：Calculate vibration signal with Delay time between pulse wave signal simultaneously extracts cardiovascular property based on the delay time of calculating.

30. according to the method for claim 29, wherein, calculate cardiovascular property the step of include：From vibration signal and arteries and veins At least one of each extraction peak point, valley point, greatest gradient point and minimum slope point fought in wave signal is as feature Point, and the step of computing relay time include：Carry out the computing relay time using the characteristic point of extraction.

31. it according to the method for claim 29, further includes：The cardiovascular property of extraction is supplied to by use by display Family.