CN108077277A - Bactericidal composition - Google Patents

Abstract

The invention discloses a kind of bactericidal composition, active ingredient is triticonazole and fludioxonil, and the mass ratio of the two is 50:1‑1:50.The present composition has apparent synergistic effect, it is effective to disease caused by Fusarium, Ustilago, Tilletia, circle nuclear cavity bacteria, Septoria, rhizoctonia solani etc., it is mainly used for preventing cereal crop, legume, fruit diseases, there is special efficacy to seed-borne disease, lasting period is up to 4 ~ 6 weeks, disease control available for cereal crop, especially seed treatment prevention loose smut of wheat, bunt, base rot disease, maize head smut, base rot disease, gall smut and bakanae disease of rice.

Description

Bactericidal composition

Technical field

The present invention relates to a kind of bactericidal composition, especially a kind of bactericidal composition containing triticonazole and its prevention farming The application of object disease, belongs to technical field of pesticide.

Background technology

Wheat and maize seed using loose smut of wheat and maize head smut as representative pass and soil-borne disease, sends out in recent years Raw degree and area bring significant damage in situation is risen year by year to wheat and maize production, and conventional method is difficult to effectively prevent, It is to control the effective way of these seed-borne diseases that efficient germicide is selected, which to carry out seed treatment,.

Triticonazole, english common name：Triticonazole is a kind of triazole bactericidal agent of Beyer Co., Ltd's research and development, has There is preferable systemic activity, and there is excellent protection, treat and root out activity.Seed treatment is mainly used as, it also can stem Foliar spray mist has seed-borne disease special efficacy, and the lasting period is up to 4 ~ 6 weeks.It can prevent including Fusarium, Puccinia, wheat class nuclear cavity Disease caused by Pseudomonas, Ustilago, Tilletia, Erysiphe, circle nuclear cavity bacteria, Septoria, Ramularia etc..With it Its triazole bactericidal agent is compared, and triticonazole advantage in prevention seed-borne disease is especially apparent.Triticonazole is efficient to black tassel bacteria, but It is not ideal enough to base rot disease preventive effect.Triazole bactericidal agent resistance risk compound in being, triticonazole are sterilized as triazole type There are cross resistances between agent, with other triazole bactericidal agents.Prevention spectrum can be expanded with other active ingredients compounding, moreover it is possible to certain Degree delays resistance to the action of a drug occurrence and development.

The content of the invention

It is an object of the invention to：There is provided it is a kind of be suitble to agriculturally use, have remarkably to cereal crop seed-borne disease Preventive effect, the efficient bactericidal composite comprising triticonazole.

In order to solve the above technical problems, inventor has been surprisingly found that sterilizing by substantial amounts of indoor bioassay screening test Azoles is compounded with fludioxonil with certain proportion, is had significant synergies to wheat and smut of maize bacterium.

Fludioxonil, english common name：Fludioxonil is novel wide spectrum, the non-internal-absorting of Syngenta Co., Ltd's exploitation Pyrroles's series bactericidal agent, have the characteristics that efficiently, it is low-risk, safe, be the seed treatment kind of current global marketing amount maximum One of.Fludioxonil mechanism of action is unique with existing fungicide no interactions resistance.Fludioxonil wide sterilization spectrum, application mode are relatively more Sample high and low waits fungal diseases available for foliar spray prevention is a variety of, it can also be used to which soil treatment (apply, pouring root, mixes soil and spreads by punching Apply) and seed treatment prevention various crop root disease.

Fludioxonil wide sterilization spectrum, but interior property and it is therapeutic not enough, can to make up fludioxonil therapeutic not with triticonazole compounding The shortcomings that sufficient.Fludioxonil corn brown foot rot is with obvious effects, and triticonazole can expand prevention spectrum with fludioxonil compounding.

On the basis of above-mentioned discovery, by carrying out the quantitative analysis of synergy to composition, form the present invention's Technical solution, i.e., using triticonazole as a kind of active ingredient, using fludioxonil as another active ingredient, the quality of triticonazole and fludioxonil Than for 1:50~50:1, preferred mass ratio is 1:20~20:1, more preferable mass ratio is 1:10~10:1.

The present composition can be prepared into the dosage form of suitable agricultural use by known method, active ingredient in preparation Total content is 5%-85%.

The adjuvant that uses includes dispersant, wetting agent, antifreezing agent etc. and other is beneficial in the composition of the present invention The known substance that ingredient is stablized in storage and use and drug effect plays is imitated, is all to commonly use in pesticidal preparations or allow to use Various composition is not particularly limited, and specific ingredient and dosage are determined according to recipe requirements by simple experiment.

Product described in the invention can be provided in the form of finished product preparation, i.e., each substance has mixed in composition, combination The ingredient of object can also be provided with unit dose form, be used in mixed way according to needs.

The bactericidal composition of the present invention is mainly used for the prevention of cereal crop kind biography and soil-borne disease, and especially wheat dissipates Smut, bunt, base rot disease, maize head smut, base rot disease and bakanae disease of rice are preferred for prevention wheat and dissipate Smut, bunt, maize head smut, base rot disease and bakanae disease of rice.

Compared with prior art, what the present invention generated has the beneficial effect that：（1）Compared with single dose, the bactericidal composition is to disease Evil has apparent synergy, improves control effect；（2）Field dosage can be greatly decreased, effectively reduce environmental pollution and agriculture Medicine remains and reduces production and application cost；（3）The mechanism of action of active ingredient is different in bactericidal composition, reduces To the single selection pressure of pathogen, the speed that is conducive to overcome and delay pathogen resistance to generate；（4）Compared with single dose, Prevention spectrum can be expanded.

Specific embodiment

In order to make the purpose , technical scheme and advantage of the present invention be clearer, present invention specific examples below It illustrates, but the present invention is limited to absolutely not these examples.

The present composition using triticonazole and fludioxonil as active ingredient, between them combination there is apparent association to disease Same synergistic effect rather than just the simple addition of two kinds of pharmacy effects, is specifically illustrated with following bioassay example.

Bioassay example 1：Triticonazole compounds with fludioxonil and the Toxicity Determination of Sporisorium reilianum is tested.

Subjects：Sporisorium reilianum（Sporisorium holci-sorghi）(outdoor is picked up from through indoor separation Culture）

Test method：Test reference《Farm-chemical indoor determination test rule NY/T 1156.17-2009 and NY/T 1156.6- 2006》, using turbidity-elisa plate method.Under aseptic technique, 75 μ L band bacteria culture fluids are drawn successively with liquid-transfering gun to distinguish It adds in each aperture of sterilized elisa plate.Then 75 μ L various concentrations are drawn successively from low concentration to high concentration with liquid-transfering gun Liquid, make liquid with bacteria culture fluid mixed in equal amounts.And blank control is set, often handle 4 repetitions.

ELISA Plate is placed on shaking table, training 84h is shaken under the conditions of 28 DEG C, 150r/min.With microplate reader measure 650nm or Absorbance under 655nm wavelength different disposals.

It records its data and carries out interpretation of result, carry out statistical analysis with DPS data processing softwares, calculate the EC of each medicament₅₀, Then co-toxicity coefficient is calculated by the abundant methods of Sun Yun（CTC）.Inhibiting rate calculation formula is as follows：

Survey toxicity index（ATI）=（Standard agent EC₅₀/ reagent agent EC₅₀）×100

Theoretical toxicity index（TTI）B in percentage composition+B medicament toxicity index × mixture of A in=A medicament toxicity index × mixture Percentage composition

Co-toxicity coefficient（CTC）=[mixture surveys toxicity index（ATI）/ mixture theoretical toxicity index（TTI）]×100

When CTC≤80, then composition shows as antagonism, and as 80 ＜ CTC ＜ 120, then composition shows as summation action, when CTC >=120, then composition show as synergistic effect.

1 different disposal of table is to the Toxicity Determination result of the test of Sporisorium reilianum

Measurement result shows the proportioning of triticonazole and fludioxonil 50:1-1:When between 50, have to Sporisorium reilianum bright Aobvious synergistic effect, 20:1-1:When between 20, synergistic effect becomes apparent from, and co-toxicity coefficient is all more than 146.

Bactericidal composition of the present invention can be prepared into any one dosage form of suitable agricultural use by known method, compared with Good dosage form has microcapsule suspending agent, suspending agent, suspension seed-coating agent, missible oil, aqueous emulsion, microemulsion, wettable powder, water-dispersible grain Agent or granule.It is illustrated below with specific embodiment, percentage is mass percent in all formulas.

Embodiment 1：21% triticonazole fludioxonil suspending agent

Triticonazole 20%, fludioxonil 1%, methyl naphthalene sulfonate formaldehyde condensate 10%, xanthans 1%, bentonite 1%, glycerine 1%, Water complements to 100%.

The each components such as active ingredient, dispersant, wetting agent, thickener, antifreezing agent and water are mixed in the ratio of formula It is even, 21% triticonazole fludioxonil suspending agent is obtained after ground and/or high speed shear.

The embodiment is applied to prevention loose smut of wheat.21% triticonazole fludioxonil suspending agent is used by active ingredient The seed dressing of 25 grams/double centner seed is measured, loose smut of wheat morbidity investigates preventive effect, preventive effect 83.7% after stablizing.Comparison medicament 25% The azole suspending agent that sterilizes is dressed seed by 25 grams/double centner of effective ingredient consumption seed, and 25 g/l of fludioxonil suspension seed-coating agents are by effective 5 grams/double centner of Ingredient Amount seed is dressed seed, and preventive effect is respectively 72.8%, 63.8%.Triticonazole is made with synergy after fludioxonil compounding With apparent, single dose is significantly better than to the preventive effect of loose smut of wheat.

Embodiment 2：51% triticonazole fludioxonil suspending agent

Triticonazole 50%, fludioxonil 1%, thermally coupled distillation columns 8%, carboxymethyl cellulose 1%, white carbon 1%, the third three Alcohol 4%, water complements to 100%.

The each components such as active ingredient, dispersant, wetting agent, thickener, antifreezing agent and water are mixed in the ratio of formula It is even, 51% triticonazole fludioxonil suspending agent is obtained after ground and/or high speed shear.

The embodiment is applied to the prevention bunt of wheat.51% triticonazole fludioxonil suspending agent is used by active ingredient The seed dressing of 25 grams/double centner seed is measured, bunt of wheat morbidity investigates preventive effect, preventive effect 80.4% after stablizing.Comparison medicament 25% The azole suspending agent that sterilizes is dressed seed by 25 grams/double centner of effective ingredient consumption seed, and 25 g/l of fludioxonil suspension seed-coating agents are by effective 5 grams/double centner of Ingredient Amount seed is dressed seed, and preventive effect is respectively 70.8%, 65.1%.Triticonazole is made with synergy after fludioxonil compounding With apparent, single dose is significantly better than to the preventive effect of the bunt of wheat.

Embodiment 3：11% triticonazole fludioxonil suspending agent

Triticonazole 10%, fludioxonil 1%, methyl naphthalene sulfonate formaldehyde condensate 3%, sodium lignosulfonate 5%, xanthans 1%, silicone oil 1%, Glycerine 1%, water complements to 100%.

The each components such as active ingredient, dispersant, wetting agent, thickener, antifreezing agent and water are mixed in the ratio of formula It is even, 11% triticonazole fludioxonil suspending agent is obtained after ground and/or high speed shear.

The embodiment is applied to prevention wheat base rot disease.11% triticonazole fludioxonil suspending agent is used by active ingredient Measure 200g/hm²It is diluted with water leaching root, the preventive effect of 15 days is 96.3% after medicine.Comparison medicament 25% sterilize azole suspending agent by effectively into Divide dosage 200g/hm²Effective ingredient consumption 200g a.i./hm are pressed with 50% fludioxonil wettable powder², it is used with same method, 15 days preventive effects are respectively 71.4%, 83.7% after medicine.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, to wheat base rot disease Preventive effect be significantly better than single dose.

Embodiment 4：21% triticonazole fludioxonil aqueous emulsion

Triticonazole 1%, fludioxonil 20%, turpentine-based vegetable oil solvent ND-45 20%, calcium dodecyl benzene sulfonate 5%, agriculture breast 600# 5%, water complements to 100%.

Active compound, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；Water-soluble component and water are mixed to prepare Water phase；Under high velocity agitation, it is oil phase is mixed with water, 21% triticonazole fludioxonil aqueous emulsion is made.

The embodiment is applied to prevention Causal Organism of Maize Basal Stalk.21% triticonazole fludioxonil aqueous emulsion is used by active ingredient Measure 200g/hm²It is diluted with water leaching root, the preventive effect of 15 days is 94.1% after medicine.Comparison medicament 25% sterilize azole suspending agent by effectively into Divide dosage 200g/hm²Effective ingredient consumption 200g/hm is pressed with 50% fludioxonil wettable powder², used with same method, after medicine 15 days preventive effects are respectively 70.3%, 82.3%.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, and Causal Organism of Maize Basal Stalk is prevented Effect is significantly better than single dose.

Embodiment 5：15% triticonazole fludioxonil microemulsion

Triticonazole 3%, fludioxonil 12%, turpentine-based vegetable oil solvent ND-45 15%, isopropanol 15%, agriculture breast 500# 5%, agriculture breast 1601# 5%, water complements to 100%.

Active compound, solvent, emulsifier are added together, make to be dissolved into homogeneous oil phase；Water-soluble component and water are mixed to prepare Water phase；Under high velocity agitation, it is oil phase is mixed with water, 15% triticonazole fludioxonil microemulsion is made.

The embodiment is applied to prevention maize head smut.15% triticonazole fludioxonil microemulsion is used by active ingredient Measure 200g/hm²It is diluted with water leaching root, the preventive effect of 15 days is 68.3% after medicine.Comparison medicament 25% sterilize azole suspending agent by effectively into Divide dosage 200g/hm²Effective ingredient consumption 200g/hm is pressed with 50% fludioxonil wettable powder², used with same method, after medicine 15 days preventive effects are respectively 62.1%, 54.3%.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, and maize head smut is prevented Effect is significantly better than single dose.

Embodiment 6：51% triticonazole fludioxonil missible oil

Triticonazole 1%, fludioxonil 50%, turpentine-based vegetable oil solvent ND-45 20%, agriculture breast 1601# 5%, agriculture breast 500# 5%, two Toluene complements to 100%.

Active ingredient, emulsifier and solvent are sequentially added in the ratio of formula in mixing kettle, stirred evenly, is made 51% Triticonazole fludioxonil missible oil.

The embodiment is applied to rotten of Maize at Seedling Stage of prevention.51% triticonazole fludioxonil missible oil is pressed into effective ingredient consumption 200g/hm²It is diluted with water leaching root, the preventive effect of 15 days is 96.8% after medicine.Comparison medicament 25% sterilizes azole suspending agent by active ingredient Dosage 200g/hm²Effective ingredient consumption 200g/hm is pressed with 50% fludioxonil wettable powder², used with same method, 15 after medicine Its preventive effect is respectively 76.4%, 86.3%.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, to the Maize at Seedling Stage preventive effect of rotten Significantly better than single dose.

Embodiment 7：24% triticonazole fludioxonil wettable powder

Triticonazole 20%, fludioxonil 4%, lauryl sodium sulfate 2%, sodium lignin sulfonate 5%, naphthalene sulfonate 3%, kaolin is supplied To 100%.

Active ingredient, wetting agent, dispersant and filler etc. are sufficiently mixed in the ratio of formula, through ultra-fine pulverizer disintegrating Afterwards to get 24% triticonazole fludioxonil wettable powder.

The embodiment is applied to prevention bakanae disease of rice.24% triticonazole fludioxonil wettable powder is pressed into active ingredient Dosage 200g/hm²Seedbed pouring is diluted with water, bakanae disease morbidity is investigated when stablizing, preventive effect 77.8%.Comparison medicament 25% sterilizes Azole suspending agent presses effective ingredient consumption 200g/hm²Effective ingredient consumption 200g/hm is pressed with 50% fludioxonil wettable powder², with same Quadrat method uses, and it is respectively 68.4%, 66.5% that preventive effect is investigated after medicine.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, right The preventive effect of bakanae disease of rice is significantly better than single dose.

Embodiment 8：22% triticonazole fludioxonil wettable powder

Triticonazole 2%, fludioxonil 20%, lauryl sodium sulfate 2%, sodium lignin sulfonate 5%,

Naphthalene sulfonate 3%, kaolin complements to 100%.

Active ingredient, wetting agent, dispersant and filler etc. are sufficiently mixed in the ratio of formula, through ultra-fine pulverizer disintegrating Afterwards to get 22% triticonazole fludioxonil wettable powder.

The embodiment is applied to prevention bakanae disease of rice.22% triticonazole fludioxonil wettable powder is pressed into active ingredient Dosage 200g/hm²Seedbed pouring is diluted with water, bakanae disease morbidity is investigated when stablizing, preventive effect 94.8%.Comparison medicament 25% sterilizes Azole suspending agent presses effective ingredient consumption 200g/hm²Effective ingredient consumption 200g/hm is pressed with 50% fludioxonil wettable powder², after medicine It is respectively 82.1%, 79.6% to investigate preventive effect.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, to the preventive effect of bakanae disease of rice Significantly better than single dose.

Embodiment 9：85% triticonazole fludioxonil water dispersible granules

Triticonazole 42.5%, fludioxonil 42.5%, alkyl how sodium sulfonate 2%, sodium lignin sulfonate 1.5%, lauryl sodium sulfate 1.5%, urea 2%, kaolin complements to 100%.

Active ingredient, dispersant, wetting agent, disintegrant and filler are uniformly mixed in the ratio of formula, through air-flow crushing Into wettable powder, add a certain amount of water mixing extruding and make material.85% triticonazole fludioxonil water is obtained after dry sieve Dispersible granule.

The embodiment is applied to prevention loose smut of wheat.By 85% triticonazole fludioxonil water dispersible granules by effectively into The seed dressing of 10 grams/double centner of dosage seed, loose smut of wheat morbidity is divided to investigate preventive effect, preventive effect 83.4% after stablizing.Control Medicament 25% sterilizes azole suspending agent by the seed dressing of 25 grams/double centner of effective ingredient consumption seed, 25 g/l of fludioxonil suspension seed-coating agents It dresses seed by 5 grams/double centner of effective ingredient consumption seed, preventive effect is respectively 72.1%, 67.4%.After triticonazole is compounded with fludioxonil Synergistic effect is apparent, is significantly better than single dose to the preventive effect of loose smut of wheat.

Embodiment 10：5% triticonazole fludioxonil granule

Triticonazole 1%, fludioxonil 4%, white carbon 6%, adhesive 1%, colorant 0.5%, granular calcium carbonate complements to 100%.

The embodiment is applied to Causal Organism of Maize Basal Stalk.5% triticonazole fludioxonil granule is pressed into effective ingredient consumption 200g/hm²The preventive effect spread fertilizer over the fields 21 days behind seedbed, medicine is 95.2%.5% triticonazole granule of comparison medicament presses effective ingredient consumption 200g/hm²Effective ingredient consumption 200g/hm is pressed with 1% fludioxonil granule², used with same method, 21 days preventive effect difference after medicine For 72.4%, 83.6%.Synergistic effect is apparent after triticonazole is compounded with fludioxonil, the preventive effect of Causal Organism of Maize Basal Stalk is significantly better than single Agent.

Embodiment 11：25% triticonazole fludioxonil microcapsule suspending agent

Triticonazole 20%, fludioxonil 5%, fatty alcohol polyoxyethylene ether AEO-10 12%, polymeric MDI 1%, epoxidized soybean oil 4.5%, ethylenediamine 0.5%, polycarboxylic acid salt's dispersant SP-3936 4%, 2 % of aluminium-magnesium silicate, propylene glycol 2.5%, sorbic acid Potassium 0.5%, organosilicon 0.1%, water complements to 100%.

Triticonazole and fludioxonil active compound are added in into methyl diphenylene diisocyanate MDI and are stirring evenly and then adding into OP-10, is mixed Close uniformly obtained oil phase；Emulsifier fatty alcohol polyoxyethylene ether AEO-10 is added in deionized water and is stirred evenly (water phase)；Preparation Good oil phase forms stable O/W lotions to water phase and 8000rpm emulsification pretreatments is entered；Opening stirring, (rotating speed maintains 300rpm ), it adds in after ethylenediamine and adjusts temperature to 50 DEG C of curing cyst walls, when maintaining stable cyst material solidification temperature 2 small, to reacting After terminal, using citric acid regulation system pH=5, it is rear add in polycarboxylic acid salt's dispersant SP-3936, propylene glycol, aluminium-magnesium silicate, Potassium sorbate preservative, organic silicon defoamer stir evenly, that is, 25% triticonazole fludioxonil microcapsule suspending agent is made.Through analysis Field trial is carried out after qualified.

The embodiment is applied to prevention maize head smut.By 25% triticonazole fludioxonil microcapsule suspending agent by effectively into The seed dressing of 5 grams/double centner of dosage seed, maize head smut morbidity is divided to investigate preventive effect, preventive effect 85.3% after stablizing.Comparison medicament 25 g/l of triticonazole suspension seed-coating agents are dressed seed by 5 grams/double centner of effective ingredient consumption seed, 25 g/l of fludioxonils suspensions kind Clothing agent is dressed seed by 5 grams/double centner of effective ingredient consumption seed, and preventive effect is respectively 74.1%, 65.8% after medicine.Triticonazole is with coughing up bacterium Synergistic effect is apparent after nitrile compounding, is significantly better than single dose to the preventive effect of maize head smut.

Embodiment 12：25% triticonazole fludioxonil suspension seed-coating agent

Triticonazole 10%, fludioxonil 15%, aryl alkyl polyoxyethylene ether 8%, aerosol-OT salt 0.4, xanthans 0.42%, bentonite 0.5%, film forming agent 7%, water complements to 100%.

The each components such as active ingredient, dispersant, wetting agent, thickener, film forming agent and water are mixed in the ratio of formula It is even, through grind twice and/or high speed shear after obtain 25% triticonazole fludioxonil suspending agent.

The embodiment is applied to seed treatment and prevents loose smut of wheat.By 25% triticonazole fludioxonil microcapsule suspending agent It dresses seed by 5 grams/double centner of effective ingredient consumption seed, loose smut of wheat morbidity investigates preventive effect, preventive effect 80.3% after stablizing. 25 g/l of triticonazole suspension seed-coating agents of comparison medicament are dressed seed by 5 grams/double centner of effective ingredient consumption seed, and 25 g/l are coughed up bacterium Nitrile suspension seed-coating agent is dressed seed by 5 grams/double centner of effective ingredient consumption seed, and preventive effect is respectively 74.5%, 66.1% after medicine.Sterilizing Synergistic effect is apparent after azoles is compounded with fludioxonil, is significantly better than single dose to the preventive effect of loose smut of wheat.

Embodiment 13：25% triticonazole fludioxonil suspension seed-coating agent

Triticonazole 12%, fludioxonil 13%, aryl alkyl polyoxyethylene ether 8%, aerosol-OT salt 0.4, xanthans 0.42%, bentonite 0.5%, film forming agent 7%, water complements to 100%.

The each components such as active ingredient, dispersant, wetting agent, thickener, film forming agent and water are mixed in the ratio of formula It is even, through grind twice and/or high speed shear after obtain 25% triticonazole fludioxonil suspending agent.

The embodiment is applied to seed treatment and prevents maize head smut.By 25% triticonazole fludioxonil suspension seed-coating agent It dresses seed by 10 grams/double centner of effective ingredient consumption seed, maize head smut morbidity investigates preventive effect after stablizing, and preventive effect is 84.2%.25% triticonazole suspension seed-coating agent of comparison medicament is dressed seed by 30 grams/double centner of effective ingredient consumption seed, and 25 g/l are coughed up Bacterium nitrile suspension seed-coating agent is dressed seed by 5 grams/double centner of effective ingredient consumption seed, and preventive effect is respectively 75.1%, 63.2% after medicine.It goes out Synergistic effect is apparent after bacterium azoles is compounded with fludioxonil, is significantly better than single dose to the preventive effect of maize head smut.

Claims (6)

1. a kind of bactericidal composition, it is characterised in that：Containing active ingredient triticonazole and fludioxonil in the bactericidal composition, two The mass ratio of person is 50:1-1:50.

2. bactericidal composition according to claim 1, it is characterised in that：The mass ratio of active ingredient triticonazole and fludioxonil For 20:1-1:20.

3. bactericidal composition according to claim 2, it is characterised in that：The mass ratio of active ingredient triticonazole and fludioxonil For 10:1-1:10.

4. bactericidal composition according to any one of claims 1 to 3, it is characterised in that：Active ingredient is total in composition Mass percentage is 5%-85%.

5. bactericidal composition according to claim 4, it is characterised in that：The dosage form of composition is suspension seed-coating agent, micro-capsule Suspending agent, suspending agent, missible oil, aqueous emulsion, microemulsion, wettable powder, water dispersible granules or granule.

6. bactericidal composition described in claim 1 is for preventing cereal crop, legume, the purposes of fruit diseases, especially It is for seed treatment prevention loose smut of wheat, the bunt of wheat, wheat base rot disease, maize head smut, Maize Stem The purposes of basal stem rot and bakanae disease of rice.