CN108072692A - A kind of portable drugs scene authentication equipment and method - Google Patents

Abstract

The invention relates to a portable on-site drug identification device and method. The device includes a control module, a rectangular ion trap mass spectrometry module, a data acquisition and processing module, a spectrogram identification and alarm module, and a result output module. Drug standard samples or actual samples are identified The device then generates a current signal and converts it into a voltage signal, and the internal clock outputs a time signal; converts the voltage signal into a digital signal; extracts the time signal and digital signal, and performs normalization and baseline correction processing; if the sample is a drug standard sample, generate a standard Spectrum library; if the sample is an actual sample, generate a sample spectrum; compare the characteristics of the sample spectrum with the standard library. The invention is small in size and light in weight and does not require complex pretreatment. Liquid samples or solid samples are directly injected and tested to realize automatic identification, alarm and printing of test results. The detection and alarm time of a single sample is less than 2s, which is suitable for on-site investigation and detection of drugs. Identification has very broad application prospects.

Description

A portable drug on-site identification device and method

technical field

The invention relates to the field of on-site drug detection equipment, in particular to a portable on-site drug identification device and method.

Background technique

Drugs have become a big cancer that endangers society. Drug crimes not only endanger personal life and health, but also endanger public safety. The focus of my country's anti-drug work during the "Twelfth Five-Year Plan" period is "blocking the source and intercepting the flow", but the drugs seized by inspection equipment each year account for only 4%, which is far from meeting the needs of the anti-drug struggle. Equipment for the detection, evidence collection and identification of toxic chemicals is imperative.

At present, the main drug detection technologies include X-ray technology, biotechnology, chromatography-mass spectrometry, capillary electrophoresis, neutron and Raman technology, and ion mobility spectrometry. Although these technologies are playing a role in my country's anti-drug work, each technology has its own defects, such as X-ray technology, whose instruments are bulky and can only be used in specific occasions such as airports and railway stations; biotechnology such as Anti-drug dogs, its stability and reliability are poor; neutron and Raman technology instruments are more expensive, and the cost of use is high.

Contents of the invention

The present invention aims at the fact that the drugs seized every year by relying on drug detection instruments and equipment in our country account for only 4% of the total amount of drugs seized, and the anti-drug equipment is far from meeting the needs of the current anti-drug struggle, and proposes a portable drug on-site identification device for Rapid detection and identification of narcotics on the spot.

The technical scheme that the present invention adopts for realizing the above object is:

The device includes a control module, a rectangular ion trap mass spectrometry module, a data acquisition and processing module, a spectrum identification and alarm module, and a result output module;

The control module communicates with the rectangular ion trap mass spectrometry module through wires and network cables, so as to realize the overall control of the working state of the rectangular ion trap mass spectrometry module;

The rectangular ion trap mass spectrometry module performs ionization and mass analysis on drug samples, generates electrical signals, and transmits the electrical signals to the data acquisition and processing module through wires;

The data acquisition, processing and analysis module converts the electrical signal into a digital signal, generates mass spectrum data, and feeds the mass spectrum data back to the control module through the COM interface, and the control module displays the mass spectrum;

The identification and alarm module obtains the mass spectrum data from the data acquisition and processing analysis module, compares it with the data in the established standard spectrum library, feeds back the comparison result to the control module for display on the computer, and sends it to the result output in the form of code module;

The result output module converts the identification result code into text and prints it out.

The control module is composed of integrated circuit board, embedded industrial computer and control software. Among them, the integrated circuit board is composed of a power supply board, a mass spectrometer control board, a high-voltage power supply board and a radio frequency amplifier; the embedded industrial computer is equipped with a screen touch function, and the screen is located directly above the instrument and adopts a flip-open design.

The rectangular ion trap mass spectrometry module includes: thermal desorption sampler, vacuum ultraviolet lamp ionization chamber, discontinuous atmospheric pressure interface (DAPI), vacuum system, rectangular ion trap mass analyzer and positive ion detector. Among them, the thermal desorption sampler is placed vertically, and the sample inlet faces the front of the instrument; the sampler and the ionization chamber of the vacuum ultraviolet lamp are connected by metal pipes and ferrules, and are wrapped with asbestos and other thermal insulation materials for insulation; The ultraviolet lamp is placed at 90 degrees to the metal pipe for sampling, and the gaseous molecules of the sample enter the ionization chamber close to the lamp head; the ionization chamber and the vacuum system are connected through a discontinuous atmospheric pressure interface, and the discontinuous atmospheric pressure Only when the interface is opened with a specific voltage signal, the ions enter the vacuum system, and then are analyzed by the rectangular ion trap mass analyzer, detected by the positive ion detector, and the mass spectrum is obtained after being analyzed by the data acquisition and processing system. The vacuum system consists of a vacuum chamber, an 80L or 60L molecular pump, an 8L diaphragm pump, and a micro-Pirani and cold cathode composite vacuum gauge; the vacuum chamber is a cuboid, and its size is: 14cm*11.5cm*6.6cm.

The specific voltage signal is: a DC voltage signal applied by pulse, the amplitude is 24V, the duration can be adjusted between 1ms and 9s according to the needs, and the voltage is applied once during a mass spectrometry analysis process.

The spectrum identification and alarm module is embedded in the mass spectrometry control software, and consists of a data processing algorithm and a drug characteristic mass spectrum peak identification database. The drug characteristic mass spectrum peak identification database is obtained through a large number of experiments and entered manually.

The result output module is a printer, which is used to print out the identification results, and the printing paper can be replaced.

The overall layout of the instrument revolves around the vacuum system. The instrument structure is divided into upper and lower layers, the lower layer is molecular pump, diaphragm pump, sampling pump and cooling fan, the upper layer is mainly embedded industrial computer, sampler, ionization chamber, discontinuous atmospheric pressure interface and vacuum chamber; power supply The power supply board is located at the lower left side of the instrument and placed vertically. The mass spectrometer control board and the high-voltage power supply board are stacked together and located at the front of the instrument and placed vertically. The RF amplifier is suspended on the outer wall of the vacuum chamber by screws and is located at the right rear of the instrument. The printer It is fixed on the instrument case and located above the computer motherboard.

The power supply board and the mass spectrometer control board communicate through the 485 interface; the mass spectrometer control board communicates with the computer through the network cable interface.

The thermal analysis sampler needs to be used in conjunction with a sampling cloth and a path of carrier gas. The sampling cloth is used to accept liquid or solid samples. Its material is polytetrafluoroethylene. The size of the sampling cloth is 105mm*28mm. The flow rate is adjusted by the gas flow regulating valve. The drying tube is located on the left rear side of the instrument and fixed on the bottom plate; there is also a reagent molecule adding device in the carrier gas pipeline, which is fixed on the sampler bracket to provide auxiliary ionization for adding reagent molecules.

An identification method for a portable drug on-site identification device, comprising the following steps:

Step 1: The drug standard sample or actual sample generates a current signal after passing through the rectangular ion trap mass spectrometry module. The acquisition card collects the current signal, and converts the current signal into a voltage signal through IV conversion. At the same time, the internal clock outputs a time signal and stores it in the memory. middle;

Step 2: The voltage signal is received by the D/A chip, through the analog-to-digital conversion circuit, the voltage signal is converted into a digital signal, and stored in the memory;

Step 3: The data acquisition and processing analysis module extracts the time signal and digital signal from the memory, and performs normalization and baseline correction processing;

Step 4: Judging that if the sample is a drug standard sample, the processed data will generate a standard spectrum and be included in the standard library. The standard library can be expanded at any time according to actual needs; if the sample is an actual sample, the processed data will be Generate a sample spectrum;

Step 5: Compare the characteristics of the sample spectrum with the standard library. If the characteristic peak of the sample spectrum is the same as that of a standard sample in the standard library, an alarm will be issued, otherwise it will be displayed as not detected.

The normalization process is to change the absolute value of the mass spectrum peak intensity into a relative value relationship through a normalization operation, that is

Y={y _i =f(N(x _{1, j} ), N(x _{2, j} ),..., N(x _{m, j} ))|x _{k, i} ∈ _{X k, i} = 1, 2 ,...,n,k=1,2,...m}

Among them, Y is the result of the normalization operation, x _{k, j} are arbitrary quantized values, X _k is the sample interval, and N(x) is the normalization function.

The baseline correction process is: using the asymmetric least squares method to remove baseline noise to make it smoother

The optimization goal is:

argmin[∑ _i w _i (y _i -z _i ) ² +λ∑ _i (Δ ² z _i ) ² ] (1)

In formula (1), w _i is the weight factor, and w _i is selected in an asymmetric way. When y _i > z _i , w _i = p, and when y _i < z _i , w _i = 1-p, p is the fitting function, y _i is the unknown, z _i is the sample average value, Δ is the second-order difference operator, and λ is the regularization parameter (also called the compromise factor); the first item in formula (1) represents the fitting function The degree of asymmetric fit with the original data; the second item is to ensure the smoothness of the fitting function, and the compromise factor λ plays a role in balancing the degree of asymmetric approximation and smoothness;

Minimizing formula (1), we can get:

(W+λD ^T D)z=W ^y (2)

In formula (2), W is a diagonal matrix composed of weight factor w (itself a vector), that is, W=diag(w), D is the second-order derivative matrix of z, that is, Dz=Δ ² z, D ^T is refers to the matrix about D, z is the estimated baseline equation;

Solve (2) to get the estimated baseline equation:

z＝(W+λD ^T D) ^-1 W _y (3)

In formula (3),

The feature comparison is:

Compare the molecular ion peak and its characteristic fragment ion peak position corresponding to the effective component in the standard sample or the actual sample. If the mass spectrum peak of the actual sample is the same as the peak position of at least one standard drug in the standard library, it is considered that the Contains the same type of drug as it.

The standard spectrum is: the mass spectrum generated after the drug standard sample is analyzed by the drug on-site identification instrument. For the same drug identification instrument, one drug standard sample corresponds to one standard spectrum.

The present invention has the following beneficial effects and advantages:

1. The outstanding advantages of the present invention are: using the rectangular ion trap mass spectrometer as the detection core, it has high sensitivity, strong stability, and high qualitative detection accuracy;

2. The present invention integrates drug detection, identification, and alarm;

3. The invention is small in size and light in weight, can be placed in a suitcase, and is easy to carry and transport;

4. The present invention does not require complex sample pretreatment, and can directly analyze solid and liquid samples;

5. The present invention has fast analysis and detection speed, small size and light weight, and can realize on-site rapid detection, identification and automatic alarm of drugs, and the sample detection and alarm time is less than 2s;

6. The present invention is equipped with a touch screen, without additional input devices such as mouse and keyboard.

Description of drawings

Fig. 1 is a functional block diagram of the drug on-the-spot identification device of the present invention;

Fig. 2 is a schematic diagram of the device structure of the on-site drug identification device of the present invention;

Fig. 3 is the structure and work flow diagram of the on-the-spot drug identification device of the present invention;

Fig. 4 is a flow chart of identifying samples by the on-site narcotics identification device of the present invention.

Among them, 1-embedded industrial computer, 2-power supply board, 3-mass spectrometer control, 4-radio frequency amplifier, 5-thermal desorption sampler, 6-vacuum ultraviolet lamp ionization chamber, 7-discontinuous atmospheric pressure interface (DAPI ), 8-rectangular ion trap mass analysis system, 9-vacuum pump system, 10-cooling fan, 11 power supply board, 12-printer, 13-drying tube, 14-reagent molecule adding device.

Detailed ways

The present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments.

In order to make the content of the present invention clearer and easier to understand, the content of the present invention will be described in detail below in conjunction with specific embodiments and accompanying drawings.

The schematic diagram of the functional framework of the instrument is shown in Figure 1. The instrument includes: a control module I, a rectangular ion trap mass spectrometry module II, a data acquisition and processing module III, a spectrum identification and alarm module IV, and a result output module V. Among them, the control module I communicates with the rectangular ion trap mass spectrometry module II through wires and network cables, so as to realize the overall control of the working state of the rectangular ion trap mass spectrometry module II;

Rectangular ion trap mass spectrometry module II conducts ionization and mass analysis on drug samples, generates electrical signals, and transmits the electrical signals to data acquisition and processing module III through wires;

The data acquisition and processing module III converts the electrical signal into a digital signal, generates mass spectrum data, and feeds the mass spectrum data back to the control module I through the COM interface, and the control module I draws and displays the mass spectrum through the computer;

The spectrum identification and alarm module IV obtains mass spectrum data from the data acquisition and processing module III, compares it with the data in the established standard spectrum library, and feeds back the comparison results to the control module I for display on the computer, and downloads the data in the form of code Send to the result output module V;

The result output module V converts the identification result code into text and prints it out.

Control module 1 is made up of integrated circuit board, embedded industrial computer 1 and control software. Among them, the integrated circuit board is composed of power supply board 2, mass spectrometer control 3 and radio frequency amplifier 4; the embedded industrial computer is equipped with a screen touch function, and the screen is located directly above the instrument, and adopts a foldable opening design.

Rectangular ion trap mass spectrometry module II includes: thermal desorption sample injector 5 , vacuum ultraviolet lamp ionization chamber 6 , discontinuous atmospheric pressure interface (DAPI) 7 , and rectangular ion trap mass analysis system 8 . Among them, the thermal desorption sampler 5 is placed vertically, and the sample inlet faces the front of the instrument; the sampler 5 and the ionization chamber 6 of the vacuum ultraviolet lamp are connected through metal pipes and ferrules, and are wrapped with asbestos and other thermal insulation materials for Heat preservation; the vacuum ultraviolet lamp is placed vertically with the metal pipe for sampling, and the gaseous molecules of the sample enter the ionization chamber 6 close to the lamp head; the ionization chamber and the vacuum system are connected through the discontinuous atmospheric pressure interface 7, and the discontinuous atmospheric pressure interface is kept in a normally closed state , only when a specific voltage signal is received, the interface is opened, ions enter the vacuum system, and then are analyzed by the rectangular ion trap mass analyzer, detected by the positive ion detector, and the mass spectrum is obtained after analysis by the data acquisition and processing module III. The vacuum system consists of a vacuum chamber, an 80L or 60L molecular pump, an 8L diaphragm pump, and a composite vacuum gauge with micro-Pirani and cold cathode; the vacuum chamber is a cuboid, and its size is: 14cm*11.5cm*6.6cm .

The spectrum recognition and alarm module IV is embedded in the mass spectrometry control software, and is composed of a data processing algorithm and a drug characteristic mass spectrum peak recognition database. The drug characteristic mass spectrum peak recognition database is obtained through a large number of experiments and entered manually.

The result output module, the main part is a micro-printer, which is used to print out the identification results, and the printing paper can be replaced.

The overall layout of the instrument revolves around the vacuum system. The instrument structure is divided into upper and lower layers, the lower layer is the vacuum pump system 9 and cooling fan 10, the upper layer is mainly embedded industrial computer 1, sample injector 5, ionization chamber 6, discontinuous atmospheric pressure interface 7 and vacuum chamber 8; power supply The board 11 is located on the lower left side of the instrument, placed vertically, and the mass spectrometer control board and the high-voltage power supply board 3 are stacked together and located on the front side of the instrument, placed vertically; the radio frequency amplifier is suspended on the outer wall of the vacuum chamber by screws, and is located on the right rear side of the instrument; Printer 12 is fixed on the instrument shell, is positioned at the top of computer motherboard.

The power supply board and the mass spectrometer control board communicate through the 485 interface; the mass spectrometer control board communicates with the computer through the network cable interface.

The thermal analysis sampler needs to be used in conjunction with a sampling cloth and a path of carrier gas. The sampling cloth is used to accept liquid or solid samples, and its material is polytetrafluoroethylene. The size of the sampling cloth is 105mm*28mm; The gas flow is adjusted by the gas flow regulating valve. The drying tube 13 is located on the left rear side of the instrument and is fixed on the bottom plate; there is also a reagent molecule adding device 14 in the carrier gas pipeline, which is fixed on the sampler bracket to provide reagent molecules. Auxiliary ionization.

Example 1

Figure 1 shows a schematic diagram of the functional framework of the on-the-spot drug identification device. It can be seen from the figure that the instrument includes: control module I, rectangular ion trap mass spectrometry module II, data acquisition and processing module III, spectrum identification and alarm module IV and result output module V.

Example 2

Figure 2 shows a schematic diagram of the equipment structure of the on-the-spot drug identification device. As shown in Figure 2, preferably, the overall layout of the instrument is developed around the vacuum system. The structure layout of the instrument is divided into upper and lower layers, the lower layer is the vacuum pump system 9 and cooling fan 10, the upper layer is mainly embedded industrial computer 1, sample injector 5, ionization chamber 6, discontinuous atmospheric pressure interface 7 and vacuum chamber 8; power supply The power supply board 11 is located at the lower left side of the instrument, placed vertically, the mass spectrometer control board and the high-voltage power supply board 3 are stacked together and located at the front side of the instrument, placed vertically; the RF amplifier is hung on the outer wall of the vacuum chamber by screws, and is located at the right rear side of the instrument ; The printer 12 is fixed on the instrument shell and is located above the computer motherboard.

Rectangular ion trap mass spectrometry module II includes: thermal desorption sample injector 5 , vacuum ultraviolet lamp ionization chamber 6 , discontinuous atmospheric pressure interface (DAPI) 7 , and rectangular ion trap mass analysis system 8 . Among them, the thermal desorption sampler 5 is placed vertically, and the sample inlet faces the front of the instrument; the sampler 5 and the ionization chamber 6 of the vacuum ultraviolet lamp are connected through metal pipes and ferrules, and are wrapped with asbestos and other thermal insulation materials for Heat preservation; the vacuum ultraviolet lamp is placed at 90 degrees to the sample metal pipe, and the gaseous molecules of the sample enter the ionization chamber 6 close to the lamp head; the ionization chamber and the vacuum system are connected through a discontinuous atmospheric pressure interface 7. The thermal analysis sampler requires a sampling cloth and a carrier gas to be used together. The carrier gas is obtained from the air around the instrument extracted by the sample pump and purified by the drying tube 13.

As shown in Fig. 3, it is the structure and working flow chart of the on-the-spot drug identification device of the present invention.

Description of the structure and working process of the drug scene identification device:

For liquid samples, use a micro-sampling needle to take a certain volume, and point it on a specific position of the sampling test paper; for solid samples, gently wipe the specific position of the sampling test paper, and insert the sampling test paper into the sampling port of the injector.

The injector consists of a mechanical locking mechanism, heating block and carrier gas. The mechanical locking mechanism is used to lock the sampling test paper, and its switch is controlled by photoelectric induction; the heating block is used for thermal analysis of liquid and solid samples (making the sample change from liquid or solid to gas); the carrier gas is used to carry the gaseous sample away The injector, into the ionization chamber.

The outlet of the sampler is connected to the ionization chamber through the tetrafluoro tube. The ionization chamber is a cylindrical structure. A radio frequency VUV lamp is fixed on the left end of the cylinder to generate photons to ionize the sample. The other end of the cylinder passes through A metal capillary was connected to one end of the Discontinuous Atmospheric Pressure Interface (DAPI). The gaseous sample undergoes a series of reactions in the ionization chamber. The type of reaction can be one or more of direct photoionization reaction, proton transfer reaction, and charge transfer reaction, and finally generate sample ions.

The other end of the discontinuous atmospheric pressure interface (DAPI) is sealed and connected to the vacuum chamber through a metal capillary. The discontinuous atmospheric pressure interface is used as a switch for ion transmission. into the vacuum chamber. (Open when DAPI is in use, and close when not in use can reduce the air intake of the vacuum system, reduce the pressure of the pump set, and facilitate the miniaturization of the instrument.)

The ions entering the vacuum chamber are immediately captured by the rectangular ion trap mass analyzer, and the ions are discharged from the ion trap mass analyzer in an orderly manner by scanning the RF voltage applied to the ion trap;

The ions discharged from the ion trap directly hit the receiving electrode of the ion detector and are converted into electrical signals (the function of the ion detector is to convert ions into electrical signals), and the electrical signals are collected by the signal processing system and converted into digital The signal generates mass spectral data.

On the one hand, the generated mass spectrum data is directly drawn by the computer and displayed on the display, on the other hand, it is extracted by the spectrum identification and alarm module, and compared with the data in the established standard spectrum library (the object of comparison is the characteristic m of the sample ion. /z spectral peak), the comparison result (that is, the detection result) will be displayed in text form on the computer monitor, and can be printed by the printer.

Fig. 4 is a flow chart of identifying samples by the on-site narcotics identification device of the present invention.

An identification method for a portable drug on-site identification device, comprising the following steps:

Step 1: The drug standard sample or actual sample generates a current signal after passing through the rectangular ion trap mass spectrometry module. The acquisition card collects the current signal, and converts the current signal into a voltage signal through IV conversion. At the same time, the internal clock outputs a time signal and stores it in the memory. middle;

Step 2: The voltage signal is received by the D/A chip, through the analog-to-digital conversion circuit, the voltage signal is converted into a digital signal, and stored in the memory;

Step 3: The data acquisition and processing analysis module extracts the time signal and digital signal from the memory, and performs normalization and baseline correction processing;

Step 4: Judging that if the sample is a drug standard sample, the processed data will generate a standard spectrum and be included in the standard library. The standard library can be expanded at any time according to actual needs; if the sample is an actual sample, the processed data will be Generate a sample spectrum;

Step 5: Compare the characteristics of the sample spectrum with the standard library. If the characteristic peak of the sample spectrum is the same as that of a standard sample in the standard library, an alarm will be issued, otherwise it will be displayed as not detected.

The normalization process is to change the absolute value of the mass spectrum peak intensity into a relative value relationship through a normalization operation, that is

Y={y _i =f(N(x _{1, j} ), N(x _{2, j} ),..., N(x _{m, j} ))|x _{k, j} ∈ _{X k, i} = 1, 2 ,...,n,k=1,2,...m}

Among them, Y is the result of the normalization operation, x _{k, j} are arbitrary quantized values, X _k is the sample interval, and N(x) is the normalization function.

The baseline correction process is: using the asymmetric least squares method to remove baseline noise to make it smoother

The optimization goal is:

argmin[∑ _i w _i (y _i -z _i ) ² +λ∑ _i (Δ ² z _i ) ² ] (1)

In formula (1), w _i is the weight factor, and w _i is selected in an asymmetric way. When y _i > z _i , w _i = p, and when y _i < z _i , w _i = 1-p, p is the fitting function, y _i is the unknown, z _i is the sample average value, Δ is the second-order difference operator, and λ is the regularization parameter (also called the compromise factor); the first item in formula (1) represents the fitting function The degree of asymmetric fit with the original data; the second item is to ensure the smoothness of the fitting function, and the compromise factor λ plays a role in balancing the degree of asymmetric approximation and smoothness;

Minimizing formula (1), we can get:

(W+λD ^T D)z=W _y (2)

In formula (2), W is a diagonal matrix composed of weight factor w (itself a vector), that is, W=diag(w), D is the second-order derivative matrix of z, that is, Dz=Δ ² z, D ^T is refers to the matrix about D, z is the estimated baseline equation;

Solve (2) to get the estimated baseline equation:

z＝(W+λD ^T D) ^-1 W _y (3)

The feature comparison is:

Compare the molecular ion peak and its characteristic fragment ion peak position corresponding to the effective component in the standard sample or the actual sample. If the mass spectrum peak of the actual sample is the same as the peak position of at least one standard drug in the standard library, it is considered that the Contains the same type of drug as it.

Although the present invention has been disclosed above with preferred implementation examples, the above implementation examples are not intended to limit the present invention. Therefore, any modifications, equivalent changes and modifications made to the above implementation examples according to the technology of the present invention in order to depart from the content of the technical solution of the present invention still belong to the scope of protection of the technical solution of the present invention.

Claims (14)

1. A portable drug on-site identification device, characterized in that: The device includes a control module, a rectangular ion trap mass spectrometry module, a data acquisition and processing module, a spectrum identification and alarm module, and a result output module; The control module communicates with the rectangular ion trap mass spectrometry module through wires, so as to realize the overall control of the working state of the rectangular ion trap mass spectrometry module; The rectangular ion trap mass spectrometry module performs ionization and mass analysis on drug samples, generates electrical signals, and transmits the electrical signals to the data acquisition and processing module through wires; The data acquisition, processing and analysis module converts the electrical signal into a digital signal, generates mass spectrum data, and feeds the mass spectrum data back to the control module through the COM interface, and the control module displays the mass spectrum; The identification and alarm module obtains the mass spectrum data from the data acquisition and processing analysis module, compares it with the data in the established standard spectrum library, feeds back the comparison result to the control module for display on the computer, and sends it to the result output in the form of code module; The result output module converts the identification result code into text and prints it out. 2. The portable drug on-site identification device according to claim 1, characterized in that: the control module is made up of an integrated circuit board, an embedded industrial computer and control software; Board, high-voltage power supply board and RF amplifier; the embedded industrial computer is equipped with a touch screen function, the screen is located directly above the instrument, and adopts a flip-open design. 3. The portable drug on-site identification device according to claim 1, characterized in that: the rectangular ion trap mass spectrometry module comprises: thermal desorption sample injector, vacuum ultraviolet lamp ionization source, discontinuous atmospheric pressure interface (DAPI) and rectangular ion trap Mass analysis system; wherein, the thermal desorption sampler is placed vertically, and the sample inlet faces the front of the instrument; the sampler and the ionization source of the vacuum ultraviolet lamp are connected by a metal tube and a ferrule, and the outside is wrapped with thermal insulation materials such as asbestos Carry out heat preservation; the vacuum ultraviolet lamp is placed vertically with the metal pipe for sampling, and the gaseous molecules of the sample enter the ionization source close to the lamp head; the ionization source and the vacuum system are connected through a discontinuous atmospheric pressure interface, and the discontinuous atmospheric pressure interface is kept in a normally closed state. Only when a specific voltage signal is received, the interface is opened, ions enter the vacuum system, and then are analyzed by the rectangular ion trap mass analyzer, detected by the positive ion detector, and the mass spectrogram is obtained after being analyzed by the data acquisition and processing system; the vacuum system consists of a vacuum chamber , 80L or 60L molecular pump, 8L diaphragm pump and micro-Pirani and cold cathode composite vacuum gauge; the vacuum chamber is a cuboid, and its size is: 14cm*11.5cm*6.6cm. 4. The portable drug on-site identification device according to claim 3, characterized in that: the specific voltage signal is a DC voltage signal applied by pulses, the amplitude is 24V, and the duration can be adjusted between 1ms and 9s according to needs. This voltage is applied once during a mass spectrometry analysis. 5. The portable drug on-site identification device according to claim 1, characterized in that: the spectrum identification and alarm module is embedded in the mass spectrum control software, which is composed of a data processing algorithm and a drug characteristic mass spectrum peak identification database. The characteristic mass spectrum peak identification database is obtained through a large number of experiments and entered manually. 6. The portable drug on-site identification device according to claim 1, characterized in that: the result output module is a printer for printing out the identification results, and the printing paper can be replaced. 7. The portable drug on-site identification device according to claim 1 is characterized in that: the overall layout of the instrument is developed around the vacuum system; Fan, the upper layer is mainly embedded industrial computer, sample injector, ionization chamber, discontinuous atmospheric pressure interface and vacuum chamber; the power supply board is located at the bottom left side of the instrument, placed vertically, and the mass spectrometer control board and high-voltage power supply board are stacked together It is located on the front side of the instrument and placed vertically; the RF amplifier is suspended on the outer wall of the vacuum chamber by screws and is located on the right rear side of the instrument; the printer is fixed on the instrument shell and is located above the computer motherboard. 8. The portable drug on-site identification device according to claim 2, characterized in that: the communication between the power supply board and the mass spectrometry control board is through the 485 interface; the communication between the mass spectrometry control board and the computer is through the network cable interface. 9. The portable drug on-site identification device according to claim 3, characterized in that: the thermal analysis sample injector needs to be used in conjunction with a sampling test paper and a carrier gas; the sampling cloth is used to accept liquid or solid samples, and its material It is polytetrafluoroethylene, and the size of the sampling cloth is 105mm*28mm; the carrier gas is obtained by extracting the air around the instrument by the sampling pump and purifying it through the drying tube. The flow rate of the carrier gas is adjusted by the gas flow regulating valve. The left rear side is fixed on the bottom plate; a reagent molecule addition device is connected to the front of the thermal analysis injector and fixed on the injector bracket to provide auxiliary ionization for adding reagent molecules. 10. The identification method of the device according to any one of claims 1 to 9, characterized in that it comprises the following steps: Step 1: The drug standard sample or actual sample generates a current signal after passing through the rectangular ion trap mass spectrometry module. The acquisition card collects the current signal, and converts the current signal into a voltage signal through IV conversion. At the same time, the internal clock outputs a time signal and stores it in the memory. middle; Step 2: The voltage signal is received by the D/A chip, through the analog-to-digital conversion circuit, the voltage signal is converted into a digital signal, and stored in the memory; Step 3: The data acquisition and processing analysis module extracts the time signal and digital signal from the memory, and performs normalization and baseline correction processing; Step 4: Judging that if the sample is a drug standard sample, the processed data will generate a standard spectrum and be included in the standard common library; if the sample is an actual sample, the processed data will generate a sample spectrum; Step 5: Compare the characteristics of the sample spectrum with the standard library. If the characteristic peaks of the sample spectrum are the same as those of a standard sample in the standard library, an alarm will be issued; otherwise, it will be displayed as not detected. 11. according to the described identification method of claim 10, it is characterized in that: described normalization process is by normalization operation, the absolute value of mass spectrum peak intensity becomes relative value relation, namely Y={y _i =f(N(x _{1, j} ), N(x _{2, j} ),..., N(x _{m, j} ))|x _{k, i} ∈ _{X k, i} = 1, 2 ,...,n,k=1,2,...m} Among them, Y is the result of the normalization operation, x _{k, j} are arbitrary quantized values, X _k is the sample interval, and N(x) is the normalization function. 12. according to the described identification method of claim 10, it is characterized in that: the described baseline correction process is: The optimization goal is: argmin[∑ _i w _i (y _i -z _i ) ² +λ∑ _i (Δ ² z _i ) ² ] (1) In the formula (1), w _i is the weight factor, and the weight factor w _i is selected in an asymmetric way. When y _i > z _i , w _i = p, and when y _i < z _i , w _i = 1-p , p is the fitting function, y _i is the unknown, zi _is the sample average, Δ is the second-order difference operator, and λ is the regularization parameter; Minimizing formula (1), we can get: (W+λD ^T D)z=W _y (2) In formula (2), W is a diagonal matrix composed of weight factor w, namely W=diag(w), D is the second order derivative matrix of z, namely Dz=Δ ² z, D ^T refers to the matrix about D , z is the estimated baseline equation; Solve (2) to get the estimated baseline equation: z=(W+λD ^T D) ^-1 W _y (3). 13. according to the described identification method of claim 10, it is characterized in that: described feature comparison is: Compare the molecular ion peak and its characteristic fragment ion peak position corresponding to the effective component in the standard sample or the actual sample. If the mass spectrum peak of the actual sample is the same as the peak position of at least one standard drug in the standard library, it is considered that the Contains the same type of drug as it. 14. according to the described identification method of claim 10, it is characterized in that: described standard spectral library comprises several standard spectral diagrams; The standard spectrum is: the mass spectrum generated after the drug standard sample is analyzed by the drug on-site identifier.