CN108066356A - A kind of haemodialysis concentrate - Google Patents
A kind of haemodialysis concentrate Download PDFInfo
- Publication number
- CN108066356A CN108066356A CN201810110291.8A CN201810110291A CN108066356A CN 108066356 A CN108066356 A CN 108066356A CN 201810110291 A CN201810110291 A CN 201810110291A CN 108066356 A CN108066356 A CN 108066356A
- Authority
- CN
- China
- Prior art keywords
- liquid
- haemodialysis
- dialysis
- concentration
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 238000001631 haemodialysis Methods 0.000 title claims abstract description 43
- 239000012141 concentrate Substances 0.000 title claims abstract description 24
- 239000007788 liquid Substances 0.000 claims abstract description 65
- 238000000502 dialysis Methods 0.000 claims abstract description 37
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 33
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 20
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims abstract description 20
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 18
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 17
- 239000008103 glucose Substances 0.000 claims abstract description 15
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical class [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims abstract description 13
- 238000010790 dilution Methods 0.000 claims abstract description 12
- 239000012895 dilution Substances 0.000 claims abstract description 12
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims abstract description 10
- 229960000583 acetic acid Drugs 0.000 claims abstract description 10
- 239000001110 calcium chloride Substances 0.000 claims abstract description 10
- 229910001628 calcium chloride Inorganic materials 0.000 claims abstract description 10
- 235000011148 calcium chloride Nutrition 0.000 claims abstract description 10
- 239000012362 glacial acetic acid Substances 0.000 claims abstract description 10
- 235000011147 magnesium chloride Nutrition 0.000 claims abstract description 10
- 239000001103 potassium chloride Substances 0.000 claims abstract description 10
- 235000011164 potassium chloride Nutrition 0.000 claims abstract description 10
- 239000011780 sodium chloride Substances 0.000 claims abstract description 9
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims abstract description 8
- 239000002253 acid Substances 0.000 claims abstract description 8
- 239000011734 sodium Substances 0.000 claims abstract description 8
- 229910052708 sodium Inorganic materials 0.000 claims abstract description 8
- 150000004649 carbonic acid derivatives Chemical class 0.000 claims abstract description 7
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 3
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 3
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 3
- 238000002425 crystallisation Methods 0.000 claims description 2
- 230000008025 crystallization Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 238000009738 saturating Methods 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- 239000000460 chlorine Substances 0.000 claims 1
- 229910052801 chlorine Inorganic materials 0.000 claims 1
- 235000015424 sodium Nutrition 0.000 claims 1
- 208000013016 Hypoglycemia Diseases 0.000 abstract description 5
- 230000002218 hypoglycaemic effect Effects 0.000 abstract description 4
- 235000002639 sodium chloride Nutrition 0.000 description 8
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000000322 hemodialysis Effects 0.000 description 5
- 210000003734 kidney Anatomy 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 238000000034 method Methods 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 2
- 150000002500 ions Chemical class 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- -1 Carbonic acid Hydrogen salt Chemical class 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 240000000161 Lagerstroemia indica Species 0.000 description 1
- 235000000283 Lagerstroemia parviflora Nutrition 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910001415 sodium ion Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a kind of haemodialysis concentrates, comprising haemodialysis concentration A liquid B liquid is concentrated with haemodialysis, it is made of 208.0 212.0g/L sodium chloride, 5.0 5.5g/L potassium chloride, 6.0 8.0g/L calcium chloride, 3.5 4.0g/L magnesium chlorides, 7.0 11.5g/L glacial acetic acid and 82.0 86.0g/L sodium acid carbonates, further include 35.0 41.0g/L or 70.0 82.0g/L glucose (containing a molecular crystalline water), this dialysate concentrate need to coordinate with dialysis machine to be used together, and concentrates the dilution ratio of B liquid and water for dialysis as 1 using haemodialysis concentration A liquid and haemodialysis:1.225:32.775 prepare, which is to provide hypoglycemia dialysis patient better choice, simplifies step, improves work efficiency, and simple to operate.
Description
Technical field
The present invention relates to hemodialysis technology field, more specifically, being a kind of haemodialysis concentrate.
Background technology
In dialysis procedure, internal glucose can filter out in vitro that blood glucose is made gradually to drop by dialyzer hemodialysis patients
It is low, when internal blood-sugar content is less than normal, that is, understand hypoglycemic reaction.
Patient can be used in dialysis procedure to two kinds of hemodialysis liquids, be respectively acid concentrate (abbreviation A liquid) and bicarbonate
A liquid and B liquid before must be connected and wash kidney machine by salt concentrate (abbreviation B liquid), be carried out in proportion with water for dialysis by washing kidney machine
Dilution can just obtain final dialyzate and be used for patient；Hospital the most commonly used is sugar-free A liquid (can refer to attachment two crape myrtle mountain mark
Label), dilution ratio is A liquid：B liquid:Water for dialysis=1:1.225:32.775, but the presently commercially available A liquid containing sugar, thinner ratio
Example is A liquid：B liquid:Water for dialysis=1:1.26:32.74, it is different from the ratio that sugar-free A liquid uses, to change using the A liquid containing sugar,
It then needs to adjust the setting for washing kidney machine again, and also to monitor using end each ion concentration (control of ion concentration is for dialysis
It is critically important) it is whether identical with design, so to use the A liquid containing sugar, it is necessary to it takes time to confirm whether dilution ratio is correct,
It is inconvenient and time-consuming for end for using.
The content of the invention
For deficiency more than making up, it can be lost in and need not adjust to avoid blood glucose the present invention provides one kind and wash kidney machine
A kind of haemodialysis concentrate of setting.
The scheme of the invention is：
A kind of haemodialysis concentrate concentrates A liquid by haemodialysis and is formed with haemodialysis concentration B liquid, and the blood is saturating
Analysis concentration A liquid includes 208.0-212.0g/L sodium chloride, 5.0-5.5g/L potassium chloride, 6.0-8.0g/L calcium chloride, 3.5-4.0g/
L magnesium chlorides, 7.0-11.5g/L glacial acetic acid, 35.0-41.0g/L or 70.0-82.0g/L glucose (containing a molecular crystalline water), institute
Stating haemodialysis concentration B liquid includes 82.0-86.0g/L sodium acid carbonates.
As preferred technical solution, haemodialysis concentration A liquid by sodium chloride, potassium chloride, calcium chloride, magnesium chloride,
Glacial acetic acid, glucose (containing a molecular crystalline water) composition, the haemodialysis concentration B liquid are made of sodium acid carbonate.
As preferred technical solution, the dialysate concentrate need to coordinate with dialysis machine to be used together, the haemodialysis
The dilution ratio for concentrating A liquid and haemodialysis concentration B liquid and water for dialysis is 1:1.225:32.775.
The present invention also provides a kind of haemodialysis concentrate preparation methods, which is characterized in that comprises the following steps：
1) according to the content of A liquid each components, 208.0-212.0g/L sodium chloride, 5.0-5.5g/L potassium chloride, 6.0- are weighed
8.0g/L calcium chloride, 3.5-4.0g/L magnesium chlorides, 7.0-11.5g/L glacial acetic acid and 35.0-41.0g/L or 70.0-82.0g/L Portugals
Grape sugar (contain a molecular crystalline water), adds in suitable water for dialysis and is completely dissolved and be mixed evenly；
2) according to the content of B liquid each components, 82.0-86.0g/L sodium acid carbonates are weighed, it is complete to add in suitable water for dialysis
Dissolving is mixed evenly；
3) the A liquid stirred evenly and B liquid are fills up to locking closure in plastic barrel respectively.
4) dialysate concentrate faces dilution of the used time by haemodialysis concentration A liquid and haemodialysis concentration B liquid and water for dialysis
Ratio is 1:1.225:32.775 dilute and need to be used together with dialysis machine cooperation.
The invention is provides hypoglycemia dialysis patient better choice, and hemodialysis patients are in dialysis procedure, internal Portugal
Grape sugar can filter out in vitro to continuously decrease blood glucose by dialyzer, when internal blood-sugar content is less than normal, that is, it is anti-understand hypoglycemia
Should, the loss of blood glucose can be supplemented during dialysis using the present invention, avoids the generation of hypoglycemia, and using more just
Profit, because hemodialysis liquid need to be diluted before with bicarbonate concentrate and water for dialysis, dilution ratio is the present invention:Carbonic acid
Hydrogen salt concentrate:Water for dialysis=1:1.225:32.775, this ratio makes hospital medical staff be not required to adjust again and wash kidney machine, avoids
It brings inconvenience.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment one：
1) according to the content of A liquid each components, sodium chloride, potassium chloride, calcium chloride, magnesium chloride, glucose are weighed (containing a molecule
The crystallization water) and glacial acetic acid, it adds in suitable water for dialysis and is completely dissolved and be mixed evenly；
2) according to the content of B liquid each components, sodium acid carbonate is weighed, suitable water for dialysis is added in and is completely dissolved mixing
Uniformly；
3) the A liquid stirred evenly and B liquid are fills up to locking closure in plastic barrel respectively.
As preferred technical solution, by the haemodialysis concentration A liquid of above-mentioned gained and bicarbonate concentration B liquid and dialysis
It is 1 with the dilution ratio of water:1.225:32.775 and need to dialysis machine coordinate be used together, in proportion absorb after mixed liquor in
Na ion concentration 138mmol/L, potassium ion 2mmol/L, calcium ion concentration 1.5mmol/L, magnesium ion concentration 0.5mmol/L,
Chlorine ion concentration 109mmol/L, acetate ion concentration 3.5mmol/L, concentration of glucose 5.5mmol/L, bicarbonate ion
Concentration 31.5mmol/L.
Embodiment two：
1) according to the content of A liquid each components, weigh 208.0g/L sodium chloride, 5.0g/L potassium chloride, 6.0g/L calcium chloride,
3.5g/L magnesium chlorides, 7.0g/L glacial acetic acid and 35.0g/L glucose (containing a molecular crystalline water), it is complete to add in suitable water for dialysis
Fully dissolved is mixed evenly；
2) according to the content of B liquid each components, 82.0g/L sodium acid carbonates are weighed, suitable water for dialysis is added in and is completely dissolved
It is mixed evenly；
3) the A liquid stirred evenly and B liquid are fills up to locking closure in plastic barrel respectively.
As preferred technical solution, by the haemodialysis concentration A liquid of above-mentioned gained and bicarbonate concentration B liquid and dialysis
It is 1 with the dilution ratio of water:1.225:32.775 and need to dialysis machine coordinate be used together.
Embodiment three：
1) according to the content of A liquid each components, weigh 212.0g/L sodium chloride, 5.5g/L potassium chloride, 8.0g/L calcium chloride,
4.0g/L magnesium chlorides, 11.5g/L glacial acetic acid and 82.0g/L glucose (containing a molecular crystalline water), add in suitable water for dialysis
It is completely dissolved and is mixed evenly；
2) according to the content of B liquid each components, 86.0g/L sodium acid carbonates are weighed, suitable water for dialysis is added in and is completely dissolved
It is mixed evenly；
3) the A liquid stirred evenly and B liquid are fills up to locking closure in plastic barrel respectively.
As preferred technical solution, by the haemodialysis concentration A liquid of above-mentioned gained and bicarbonate concentration B liquid and dialysis
It is 1 with the dilution ratio of water:1.225:32.775 and need to dialysis machine coordinate be used together.
Basic principle, main feature and the advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent circle.
Claims (4)
1. a kind of haemodialysis concentrate, it is characterised in that：A liquid is concentrated by haemodialysis to form with haemodialysis concentration B liquid, institute
State haemodialysis concentration A liquid include 208.0-212.0g/L sodium chloride, 5.0-5.5g/L potassium chloride, 6.0-8.0g/L calcium chloride,
3.5-4.0g/L magnesium chlorides, 7.0-11.5g/L glacial acetic acid, 35.0-41.0g/L or 70.0-82.0g/L glucose (contain a molecule
The crystallization water), the haemodialysis concentration B liquid includes 82.0-86.0g/L sodium acid carbonates.
2. a kind of haemodialysis concentrate as described in claim 1, it is characterised in that：The haemodialysis concentrates A liquid by chlorine
Change sodium, potassium chloride, calcium chloride, magnesium chloride, glacial acetic acid, glucose (containing a molecular crystalline water) composition, the haemodialysis concentrates B
Liquid is made of sodium acid carbonate.
3. a kind of haemodialysis concentrate as claimed in claim 1 or 2, it is characterised in that：The dialysate concentrate need to it is saturating
The cooperation of analysis machine is used together, and the dilution ratio of the haemodialysis concentration A liquid and haemodialysis concentration B liquid and water for dialysis is 1:
1.225:32.775。
4. a kind of haemodialysis concentrate preparation method, which is characterized in that comprise the following steps：
1) according to the content of A liquid each components, 208.0-212.0g/L sodium chloride, 5.0-5.5g/L potassium chloride, 6.0-8.0g/ are weighed
L calcium chloride, 3.5-4.0g/L magnesium chlorides, 7.0-11.5g/L glacial acetic acid and 35.0-41.0g/L or 70.0-82.0g/L glucose
It (contain a molecular crystalline water), adds in suitable water for dialysis and is completely dissolved and be mixed evenly；
2) according to the content of B liquid each components, 82.0-86.0g/L sodium acid carbonates are weighed, suitable water for dialysis is added in and is completely dissolved
It is mixed evenly；
3) the A liquid stirred evenly and B liquid are fills up to locking closure in plastic barrel respectively.
4) haemodialysis concentrate faces dilution of the used time by haemodialysis concentration A liquid and haemodialysis concentration B liquid and water for dialysis
Ratio is 1:1.225:32.775 dilute and need to be used together with dialysis machine cooperation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810110291.8A CN108066356A (en) | 2018-02-05 | 2018-02-05 | A kind of haemodialysis concentrate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810110291.8A CN108066356A (en) | 2018-02-05 | 2018-02-05 | A kind of haemodialysis concentrate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108066356A true CN108066356A (en) | 2018-05-25 |
Family
ID=62157132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810110291.8A Pending CN108066356A (en) | 2018-02-05 | 2018-02-05 | A kind of haemodialysis concentrate |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108066356A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110917422A (en) * | 2019-12-05 | 2020-03-27 | 长春海伯尔生物技术有限责任公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
| WO2021223732A1 (en) * | 2020-05-08 | 2021-11-11 | Xia Yongbiao | Blood purification concentrate |
| CN113827800A (en) * | 2021-10-26 | 2021-12-24 | 常州华岳微创医疗器械有限公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
| CN115414383A (en) * | 2022-10-14 | 2022-12-02 | 青岛普瑞森医药科技有限公司 | Hemodialysis concentrate and preparation method thereof |
| CN117919274A (en) * | 2024-01-08 | 2024-04-26 | 荣嘉医疗科技(集团)有限公司 | A hemodialysis concentrate |
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| Title |
|---|
| T.S.ING ET AL.: ""Employing L-lactic acid powder in the preparation of a dry "acid concentrate" for use in a bicarbonate-based dialysis solution-generating system: experience in hemodialysis patients"", 《THE INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS》 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110917422A (en) * | 2019-12-05 | 2020-03-27 | 长春海伯尔生物技术有限责任公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
| WO2021223732A1 (en) * | 2020-05-08 | 2021-11-11 | Xia Yongbiao | Blood purification concentrate |
| CN113827800A (en) * | 2021-10-26 | 2021-12-24 | 常州华岳微创医疗器械有限公司 | Ultrapure hemodialysis concentrated solution and preparation process thereof |
| CN115414383A (en) * | 2022-10-14 | 2022-12-02 | 青岛普瑞森医药科技有限公司 | Hemodialysis concentrate and preparation method thereof |
| CN117919274A (en) * | 2024-01-08 | 2024-04-26 | 荣嘉医疗科技(集团)有限公司 | A hemodialysis concentrate |
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Application publication date: 20180525 |