CN108065109A - A kind of feed addictive for improving laying hen intestinal health and improving immunity - Google Patents
A kind of feed addictive for improving laying hen intestinal health and improving immunity Download PDFInfo
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- CN108065109A CN108065109A CN201711433767.3A CN201711433767A CN108065109A CN 108065109 A CN108065109 A CN 108065109A CN 201711433767 A CN201711433767 A CN 201711433767A CN 108065109 A CN108065109 A CN 108065109A
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Medicines Containing Plant Substances (AREA)
- Fodder In General (AREA)
Abstract
The present invention relates to a kind of feed addictives for improving laying hen intestinal health and improving immunity, are prepared by the component of following parts by weight content：28 parts of 50 55 parts of Cortex Eucommiae, 20 25 parts of okra, 28 parts of seaweed, 29 parts of argy wormwood, 49 parts of Radix Glycyrrhizae and dandelion；By weighing after drying Cortex Eucommiae, okra, seaweed, argy wormwood, Radix Glycyrrhizae and dandelion, it is uniformly mixed according to a ratio to obtain after crushing；By its in mass ratio for 2% ratio be added to laying hen routine daily ration in feed.Compared with prior art, the present invention can effectively reduce the quantity of harmful bacteria in laying hen enteron aisle, improve the intestinal health of laying hen, meanwhile, which can stimulate the expression of the immune cell factor, and so as to enhance immunity of organisms, and effect is better than single addition.
Description
Technical field
The present invention relates to a kind of feed addictive of layer chicken field, more particularly, to one kind for improve laying hen intestinal health and
Improve the feed addictive of immunity.
Background technology
The enteron aisle of laying hen is that animal body contacts one of tissue the closest with external environment, is also exempting from for body maximum
Epidemic disease organ.The lymphoid tissue of body more than 50% is dispersed in intestinal mucosa, and a large amount of complicated micro- lifes in symbiosis in enteron aisle
Object.These microorganisms are that indispensable component, health and disease to body have closely in environment in animal body
Contact.Under normal circumstances, microflora can cause laying hen to be in a healthy state in laying hen enteron aisle, not occur
Disease.Meanwhile laying hen intestinal microflora, again with the diet of laying hen there are substantial connection, the health of laying hen is close with intestines problem
Cut phase is closed, and when in pathogenic microorganism invasion laying hen body, laying hen intestinal mucosa is damaged, and the production performance of laying hen is caused to decline, sternly
Weight will make chicken group's outburst disease, cause laying hen dead.In this case, all it is to be solved using antibiotic mostly.
In livestock breeding industry, antibiotic is widely used as feed addictive in animal diets, because antibiotic is improving animal
It plays an important role in terms of growth performance and reduction disease.However a large amount of use of antibiotic brings many secondary works
With if flora is unbalance, generation drug resistance endangers human health etc., therefore, to solve the disadvantage caused by long-time service antibiotic
End, research can improve livestock birds health, and the feed addictive for improving production performance and safe and non-toxic energy substitute antibiotics has
Significance.
The content of the invention
It is an object of the present invention to overcome the above-mentioned drawbacks of the prior art and provide one kind for improving laying hen
Intestinal health and the feed addictive for improving immunity.
The purpose of the present invention can be achieved through the following technical solutions：
A kind of feed addictive for improving laying hen intestinal health and improving immunity, by the group of following parts by weight content
Divide and be prepared：
2-8 parts of 50-55 parts of Cortex Eucommiae, 20-25 parts of okra, 2-8 parts of seaweed, 2-9 parts of argy wormwood, 4-9 parts of Radix Glycyrrhizae and dandelion.
Preferably, which is prepared by the component of following parts by weight content：
4-8 parts of 52-54 parts of Cortex Eucommiae, 22-24 parts of okra, 2-6 parts of seaweed, 6-8 parts of argy wormwood, 6-8 parts of Radix Glycyrrhizae and dandelion.
It is further preferred that the feed addictive is prepared by the component of following parts by weight content：
6 parts of 53 parts of Cortex Eucommiae, 23 parts of okra, 4 parts of seaweed, 7 parts of argy wormwood, 7 parts of Radix Glycyrrhizae and dandelion.
Preferably, which is prepared using following methods：
It weighs after Cortex Eucommiae, okra, seaweed, argy wormwood, Radix Glycyrrhizae and dandelion are dried, is uniformly mixed according to a ratio i.e. after crushing
Obtain the feed addictive for being used to improve laying hen intestinal health and improve immunity.
Preferably, it is dry using the method dried, it smashes it through 80-100 mesh sieves and takes sieved object.
Preferably, by its in mass ratio for 2% ratio be added to brood time 0-6 week old laying hens conventional daily ration in carry out
Feeding improves laying hen intestinal health and improves immunity.
The laying hen of brood time 0-6 week old, the laying hen in this period, enteron aisle and developing immune system are not perfect, micro- to cause of disease
Biological resistance is weaker, poor to extraneous environmental suitability, easily diseased, at this stage using additive, can effectively improve
The intestinal health of laying hen and raising immunity cultivate the qualified chicken group of stalwartness for meeting kind growth developmental characteristic, are later egg
Giving full play to for the production performance in chicken stage lays the first stone.
Cortex Eucommiae for temperate zone it is perennial fallen leaves wood, not only rich in a variety of conventional nutrients such as amino acid, vitamin, mineral element into
Point, also containing itself exclusive natural effective active composition such as chlorogenic acid, Cortex Eucommiae glycosides, rosin element glycosides, Gutta-percha, there is enhancing to exempt from
The effect of epidemic disease power, antibacterial anti-inflammatory, reducing blood lipid, blood glucose increasing, calmness, resisting stress etc..
It is added in poultry feed, to improving immunity of poultry, growth-promoting with good effect.
Okra is Malvaceae gumbo platymiscium, rich in amino acid, vitamin, trace element, polysaccharide, flavones and a large amount of
Unrighted acid, have antifatigue, promoting digestion and protecting liver, can reduce injury of lungs, improve immunity of organisms, antitumaous effect, diuresis,
Enhance a variety of nutrition and health care functions such as blood vessel dilatation power.Currently as feed addictive apply report on laying hen study compared with
It is few.
Seaweed is that can carry out photosynthetic self-operation plant in the lake of ocean, contains polysaccharide, unrighted acid, albumen
The ingredients such as matter, amino acid, polypeptide, taurine, polyterpene, steroid and enzyme have anticoagulation, lowering blood pressure and blood fat, antitumor etc. solely
Special function.Seaweed can improve performance of poultry, improve immunity function, reduce the load of microorganism in enteron aisle, improve poultry and
The quality of birds, beasts and eggs.
Argy wormwood is composite family artemisia herbaceos perennial, rich in changes such as volatile oil, flavonoids, folium eucalypti alkanes and triterpenes
Close object isoreactivity ingredient.Flavone compound in argy wormwood have it is anti-oxidant, remove free radical, anticancer and the multiactions such as antibacterial.
Radix Glycyrrhizae is the root and root-like stock of glycyrrhizic legume, rich in triterpene compound (glycyrrhizin also glycyrrhetate, it is sweet
Careless hypo acid etc.), flavone compound (liquiritin, different Licorice flavanone, glycyrrhizin etc.) and licorice polysaccharide class compound etc. are raw
Active substances, have moisten the lung and relieve the cough well, purging intense heat and detonicating, invigorating middle warmer and replenishing QI, the effect of relieving spasm to stop pain, mediation property of medicine.Radix Glycyrrhizae
Flavones can inhibit tyrosinase activity, remove oxyradical, and oxidation resistance is approached with vitamin E.Substantial amounts of research is also
Show in Radix Glycyrrhizae energy and/or release the noxious material in skin, and with good anti-inflammatory, antiviral, kobadrin, antibacterial,
The effects that anti-aging.
Dandelion be composite family renascent herb, rich in flavonoids, terpene, phenolic acid class, tarachrome, phytosterol,
There is broad-spectrum antibacterial, lidan liver, anti-gastric injury, antitumor, enhancing to exempt from for Sesquiterpene lactones and Coumarins isoreactivity ingredient
The effects that epidemic disease power.
The present invention is added to as a kind of feed addictive in the feed of laying hen, and can effectively reduce has in laying hen enteron aisle
The quantity of evil bacterium, improves the intestinal health of laying hen, meanwhile, the additive can stimulate the immune cell factor expression, from
And enhance immunity of organisms, and effect is better than single addition.The additive each component compatibility science of the present invention, Cortex Eucommiae mainly inhibit
The growth of Gram-negative bacteria, argy wormwood mainly inhibit fungi growth, Radix Glycyrrhizae can inhibit gram-positive bacteria, Gram-negative bacteria and
Influenza virus, dandelion primarily serve the effect for inhibiting gram-positive bacteria, and independent role, antimicrobial spectrum is all narrow, these four
It is combined between substance, can play and inhibit bacteria simultaneously, the effect of fungi and virus expands scope of restraining fungi, makes what it was obtained
Additive has the bacteriostasis of wide spectrum；Since the additive has the antibacterial activity of wide spectrum, intestines can be greatly reduced
The quantity of Escherichia coli, staphylococcus aureus in road etc., the antibacterial work of collaboration between Cortex Eucommiae, Radix Glycyrrhizae, dandelion and argy wormwood
With mutually promoting, fungistatic effect can be allowed to reach optimal, effectively reduce Escherichia coli in enteron aisle, staphylococcus aureus
Quantity.Rich in substantial amounts of bioactive substance in seaweed, protein and energy requirement in livestock and poultry diet can be met by having, and enhance body
Immunity improves the production performance of laying hen.
Compared with prior art, the invention has the advantages that：
(1) feed addictive is added to laying hen by carrying out scientific compatibility to various composition as feed addictive
In feed, additive amount dosage is few, and addition 2% just can generate good effect：The duodenal height of naps of laying hen can be improved,
Duodenal Crypt depth is made to shoal, height of naps/Crypt depth ratio (V/C values) increases, and intestines wall thickness reduction shows this
Feed addictive can improve the intestinal health of laying hen, improve the absorbability of laying hen enteron aisle；The additive can also promote egg
The development of Immune Organs of Chicken improves the immunity of laying hen, and effect is better than single addition.
(2) each ingredient selected by the feed addictive is all natural materials, all with safe and nontoxic without side-effects, nothing
The advantages that medicament residue, for egg feedstuff, can effectively improve laying hen intestinal health and improve immunity.
(3) Cortex Eucommiae selected by has synergistic effect, can allow antibacterial effect between Radix Glycyrrhizae, okra, dandelion and argy wormwood
Fruit reaches optimal, effectively reduces the quantity of Escherichia coli in enteron aisle, staphylococcus aureus.
(4) rich in substantial amounts of bioactive substance in the seaweed and okra selected by, egg in livestock and poultry diet can be met by having
White matter and energy requirement can enhance immunity of organisms, so as to improve the production performance of laying hen.
(5) feed addictive uses natural materials, is pulverized and mixed uniformly, at low cost without operations such as purifications, system
Standby simple, condition controllability is good, and obtained feed performance is stablized, which is made of crude, and between each substance
Match rational in infrastructure, preparation process is simple, and beneficial to storage, palatability is good, searches for food beneficial to laying hen.
Specific embodiment
With reference to specific embodiment, the present invention is described in detail.
Embodiment 1
A kind of feed addictive for improving laying hen intestinal health and improving immunity, by the group of following parts by weight content
Divide and be prepared：50-55 parts of Cortex Eucommiae, 20-25 parts of okra, 2-8 parts of seaweed, 2-9 parts of argy wormwood, 4-9 parts of Radix Glycyrrhizae and dandelion 2-8
Part.
The feed addictive is prepared using following methods：Cortex Eucommiae, okra, seaweed, argy wormwood, Radix Glycyrrhizae and dandelion are dried
After weigh, be uniformly mixed according to a ratio after crushing and obtain the described feed for improving laying hen intestinal health and improving immunity
Additive.Wherein, it is dry preferably using the method dried, it smashes it through 80-100 mesh sieves and takes sieved object.
By its in mass ratio for 2% ratio be added to brood time 0-6 week old laying hen routine daily rations in feed, can have
Effect improves laying hen intestinal health and improves immunity.And design tests below：
(1) experimental design
It is designed using single-factor, selects the blue brown laying hen in sea of 300 1 age in days health, be randomly divided into 5 test groups, each
5 repetitions of test group each repeat 12 chickens.Control group fed basal diet (diet recipe is as shown in table 1 below), basal diet
It is needed with reference to U.S. NRC (1994) laying hen nutrition, test group feeds basal diet+different feeds additive component respectively, tests
Phase is 28 days, free choice feeding and drinking-water during experiment.
(2) testing index
2.1 Immune Organs Indexes measure
During off-test, each test group each repeats to randomly select the middleweight blue brown laying hen 4 in health sea, butchers
(claiming live body weight before butchering) wins thymus gland, spleen and the bursa of farbricius, sucks blood on each organ with filter paper, removes fat, weigh, surveys
Determine Immune Organs Index.Immune Organs Index=immune organ weight/weight × 100
2.2 duodenum intestinal tissue somatometry of physique
During off-test, each test group often repeats to randomly select the middleweight blue brown laying hen 4 in health sea, butchers rear fast
Speed duodenum is cut it is a bit of, it is fixed with after normal saline flushing its content, being placed in 4% paraformaldehyde fixer
For 24 hours, flowing water rinses for 24 hours, and through incremental gradient dehydration of alcohol step by step, dimethylbenzene is transparent, waxdip, embedding, and paraffin section is made (per intestines
Section respectively cuts three pieces, every 0.5 μm), section dewaxing enters water, and hematoxylin --- eosin stains (HE dyeing), mounting observes each intestines
Section tissue morphology.3 visuals field are chosen in every section, per the visual field 3 villus of METHOD FOR CONTINUOUS DETERMINATION, with HPIAS-5100 high-definition colors
Pathology picture and text analysis system does quantitative analysis, measures its height of naps (VH), Crypt depth (CD) and intestinal wall thickness, each index and takes
Average value, and calculate height of naps/Crypt depth ratio (V/C values).
2.3 data processings and statistical method
Measured numerical value carries out one-way analysis of variance, LSD Multiple range tests using 22.0 statistical softwares of SPSS.Knot
Fruit is represented with mean+SD.
1 basal diet of table forms (%)
Premix composition is shown in Table 2
2 premix of table forms
Premix provides for every kilogram of daily ration：
Different tests group feed addictive composition is as shown in table 3：
3 different tests group feed addictive (2%) of table forms
Result of the test is as follows：
The comparison of laying hen duodenum intestinal tissue form is shown in Table 4：
The comparison of 4 laying hen duodenum intestinal tissue form of table
| Group | Height of naps (μm) | Crypt depth (μm) | V/C values | Intestinal wall thickness (μm) |
| Control group | 1118.23±19.38 | 112.18±7.14a | 9.98±0.79b | 112.96±6.12a |
| Test group 1 | 1132.36±32.36 | 108.23±7.26ab | 10.49±0.89ab | 107.29±8.13ab |
| Test group 2 | 1138.29±28.36 | 105.19±8.23ab | 10.87±0.98a | 104.98±7.53b |
| Test group 3 | 1157.42±35.26 | 103.23±6.16b | 11.23±1.08a | 103.98±8.26b |
| Test group 4 | 1128.63±21.13 | 106.13±7.62ab | 10.67±0.81a | 104.13±7.29b |
As shown in Table 4, compared with the control group, the duodenal height of naps of each test group is without significant difference (P ＞ 0.05),
But the trend being all improved；Compared with the control group, the Crypt depth of test group 3 significantly reduces (P ＜ 0.05), other test groups
Not significantly (P ＞ 0.05), but have a declining tendency；Compared with the control group, the V/C values of each test group all improve, wherein testing
Group 2, test group 3,4 significant difference of test group (P ＜ 0.05)；Compared with the control group, the intestinal wall thickness of each test group improves,
Middle test group 2, test group 3,4 significant difference of test group (P ＜ 0.05).
The dynamic change of laying hen Immune Organs Index is shown in Table 5：
The dynamic change (%) of 5 laying hen Immune Organs Index of table
As shown in Table 5, compared with the control group, the thymus index of each test group, index and spleen index, bursal index are significant
It improves (P ＜ 0.05), wherein, the effect of test group 3 is best.Showing the feed addictive of the present invention can promote laying hen that device is immunized
The development of official has great importance to the immunity of organism for promoting laying hen.
Conclusion：The feed addictive of the present invention can improve the duodenal height of naps of laying hen, make duodenal hidden
Nest depth shallower, height of naps/Crypt depth ratio (V/C values) increase, intestines wall thickness reduction, show that the feed addictive can be with
Improve the intestinal health of laying hen, improve the absorbability of laying hen enteron aisle；The additive can also promote the hair of laying hen immune organ
It educates, improves the immunity of laying hen.
The above-mentioned description to embodiment is for ease of ordinary skill in the art to understand and use the invention.It is ripe
Knowing the personnel of art technology obviously can easily make these embodiments various modifications, and general original described herein
It ought to use in other embodiment without having to go through creative labor.Therefore, the invention is not restricted to above-described embodiment, this fields
Technical staff's announcement according to the present invention, improvement and modification made without departing from the scope of the present invention all should be in the guarantors of the present invention
Within the scope of shield.
Claims (6)
1. a kind of feed addictive for improving laying hen intestinal health and improving immunity, which is characterized in that by following weight
The component of part content is prepared：
2-8 parts of 50-55 parts of Cortex Eucommiae, 20-25 parts of okra, 2-8 parts of seaweed, 2-9 parts of argy wormwood, 4-9 parts of Radix Glycyrrhizae and dandelion.
2. a kind of feed addictive for improving laying hen intestinal health and improving immunity according to claim 1,
It is characterized in that, is prepared by the component of following parts by weight content：
4-8 parts of 52-54 parts of Cortex Eucommiae, 22-24 parts of okra, 2-6 parts of seaweed, 6-8 parts of argy wormwood, 6-8 parts of Radix Glycyrrhizae and dandelion.
3. a kind of feed addictive for improving laying hen intestinal health and improving immunity according to claim 2,
It is characterized in that, is prepared by the component of following parts by weight content：
6 parts of 53 parts of Cortex Eucommiae, 23 parts of okra, 4 parts of seaweed, 7 parts of argy wormwood, 7 parts of Radix Glycyrrhizae and dandelion.
4. the feed addictive according to claim 1 for improving laying hen intestinal health and improving immunity, feature
It is, which is prepared using following methods：
It weighs after Cortex Eucommiae, okra, seaweed, argy wormwood, Radix Glycyrrhizae and dandelion are dried, is uniformly mixed according to a ratio after crushing and obtains
The feed addictive for being used to improve laying hen intestinal health and improve immunity.
5. the feed addictive according to claim 4 for improving laying hen intestinal health and improving immunity, feature
It is, it is dry using the method dried, it smashes it through 80-100 mesh sieves and takes sieved object.
6. the feed addictive according to claim 1 for improving laying hen intestinal health and improving immunity, feature
Be, by its in mass ratio for 2% ratio be added to brood time 0-6 week old laying hens conventional daily ration in feed, improve
Laying hen intestinal health and raising immunity.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111084292A (en) * | 2020-02-11 | 2020-05-01 | 福建省农业科学院畜牧兽医研究所 | Composite fiber additive for promoting growth performance of laying hens |
| CN111227115A (en) * | 2020-03-18 | 2020-06-05 | 广州市致善生物科技有限公司 | Feed additive and preparation method and application thereof |
| CN111802527A (en) * | 2020-06-08 | 2020-10-23 | 浙江大学 | Application of eucommia ulmoides extract in preparation of feed for improving delicate flavor of chicken |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102204629A (en) * | 2011-05-19 | 2011-10-05 | 浙江农林大学 | Feed additive and preparation method thereof |
| CN107467394A (en) * | 2017-08-21 | 2017-12-15 | 洪泽敏田农业发展有限公司 | A kind of yellow chicken feed and preparation method thereof |
-
2017
- 2017-12-26 CN CN201711433767.3A patent/CN108065109A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102204629A (en) * | 2011-05-19 | 2011-10-05 | 浙江农林大学 | Feed additive and preparation method thereof |
| CN107467394A (en) * | 2017-08-21 | 2017-12-15 | 洪泽敏田农业发展有限公司 | A kind of yellow chicken feed and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111084292A (en) * | 2020-02-11 | 2020-05-01 | 福建省农业科学院畜牧兽医研究所 | Composite fiber additive for promoting growth performance of laying hens |
| CN111084292B (en) * | 2020-02-11 | 2022-12-09 | 福建省农业科学院畜牧兽医研究所 | Composite fiber additive for promoting growth performance of laying hens |
| CN111227115A (en) * | 2020-03-18 | 2020-06-05 | 广州市致善生物科技有限公司 | Feed additive and preparation method and application thereof |
| CN111802527A (en) * | 2020-06-08 | 2020-10-23 | 浙江大学 | Application of eucommia ulmoides extract in preparation of feed for improving delicate flavor of chicken |
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