CN107929119A - A kind of composition with Whitening, spot - Google Patents
A kind of composition with Whitening, spot Download PDFInfo
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- CN107929119A CN107929119A CN201711194152.XA CN201711194152A CN107929119A CN 107929119 A CN107929119 A CN 107929119A CN 201711194152 A CN201711194152 A CN 201711194152A CN 107929119 A CN107929119 A CN 107929119A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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Abstract
The invention discloses a kind of composition with Whitening, spot, include the raw material of following percentage by weight：Moisturizer 1%~10%, antiallergic is releived agent 1%~10%, niacinamide 1%~10%, compact anti wrinkling agent 1%~10%, nanometer gold bar 1%~10%, VC ethylethers 3%~15%, α ursin 0.5%~5.0%, solvent fills reinforcing agent 14%~55%, didextrose base gallate 3.0%~15%, and above-mentioned raw materials summation is 100%.The composition of the Whitening, spot of the present invention, with junket ammonia enzyme directly in conjunction with, the oxidation of tyrosinase and DOPA is blocked, accelerates the decomposition and excretion of melanin, effectively suppresses the activity of the tyrosinase in skin, block the formation of melanin, realize light spot, whitening effect, may be used in the cosmetics of downstream, and light spot and whitening effect are good, toxicity is low, meets cosmetics laws and regulations requirement.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of composition with Whitening, spot.
Background technology
In ancient times, the mankind have found the beauty functions of gold.In pharmacopeia on Chinese history, gold have it is various not
Same medical value,《Haigoushen》：Main children shy wound, the five internal organs wind epilepsy, lose will, relieving palpitation, peace soul.《Book on Chinese herbal medicine is new again》：Easypro liver
Gas, centering intelligence, peace soul, kidney nourishing water, network of passing through, sharp joint, broken product disappear subcutaneous ulcer, control all poison of pediatric epilepsy scared, variola.Ancient Chinese
There is a kind of special beauty method in imperial palace, i.e., carries out facial massage with gold roller to keep appearance；Ancient Egypt is expensive according to legend
Woman is subcutaneously implanted superfine spun gold in table to allow face to seem tender and lovely, then coordinates herbal medicine to apply face with proof gold mask, obtains
The effect of good.Gold is also just used in cosmetics by Japan early in the river family epoch, there is skin whitening, delay skin aging
The effect of.Modern gold face-beautifying method, far away from American-European prevalence, is used till today always after India is passed to Britain.
The defence layer that skin carries can prevent the intrusion of external foreign matter, also just because of having the presence of this layer of defence layer, order
The Cosmetic Ingredient of general cosmetics is difficult to be absorbed by skin.And everyone flows faint electric current in vivo, these are faint
Phenomena such as electric current is once lacked of proper care, and color spot, microgroove, relaxation will occur for skin.It with the addition of in true yellow aurification cosmetic, gold is in itself
Just there is removing toxic substances, calmness, booster immunization power, activates DNA, cleaning and goes to wrinkle, and it is as a kind of inert metal,
With very strong anti-oxidation characteristics, external environment condition and caused peroxide and free radical in vivo can be reduced.From gold
It is identical reason that the anion discharged, which makes cell high activityization promote to absorb using utensils such as introducing apparatus with beauty parlor,
The anion discharged in gold plays the effect same with the utensil such as introducing apparatus, makes Cosmetic Ingredient be defendd from skin in layer
Infiltrate into skin bottom.
The approach of gold beauty at present, also about just only has the several method of painting and implantation skin for oral administration, outer,
Due to the limitation of technology, energy can not be extracted directly from gold and be used by skin.It is based on this it is proposed that a kind of containing receiving
The golden rod of rice has effects that the composition of Whitening, spot.
The content of the invention
The purpose of the present invention is to solve shortcoming existing in the prior art, and the one kind proposed has Whitening, spot
Composition.
A kind of composition with Whitening, spot, includes the raw material of following percentage by weight：Moisturizer 1%~10%, resists
Quick agent 1%~10% of releiving, niacinamide 1%~10%, compact anti wrinkling agent 1%~10%, nanometer gold bar 1%~10%, VC-
Ethylether 1.5%~2.5%, alpha-arbutin 0.5%~5.0%, solvent filling reinforcing agent 14%~55%, didextrose base Gallate
Acid 3.0%~15%, above-mentioned raw materials summation are 100%.
Preferably, the moisturizer is the combination of Sodium Hyaluronate and proline.
Preferably, the antiallergic releive agent for hamamelis extract, Rosa centifolia flower extract, Jasminum officinale Linn extract,
The combination of daisy flower extract.
Preferably, the combination of the anti wrinkling agent for yeast extract and oligopeptides -1 of compacting.
Preferably, 6~8nm of diameter of the nanometer gold bar, longitudinal plasmon absorption peak scope for 650~
1100nm, surface Raman enhancement correspond to draw ratio as 2~10.
Preferably, the solvent filling reinforcing agent is mixed by butanediol and calamine.
Preferably, the preparation method of the composition with Whitening, spot comprises the following steps：
S1, according to moisturizer 1%~10%, antiallergic is releived agent 1%~10%, and niacinamide 1%~10%, compacts crease-resistant
Agent 1%~10%, nanometer gold bar 1%~10%, VC- ethylethers 3%~15%, α-ursin 0.5%~5.0%, solvent is filled out
Reinforcing agent 14%~55% is filled, didextrose base gallate 3.0%~15%, above-mentioned raw materials summation weighs each raw material for 100%, standby
With；
S2, moisturizer, antiallergic are releived agent, niacinamide, the anti wrinkling agent that compacts, nanometer gold bar, VC- ethylethers, alpha-arbutin
Fill the part butanediol mixing in reinforcing agent with solvent, stirring and dissolving obtains mixture A, spare；
S3, by solvent fill reinforcing agent in calamine be dispersed in the butanediol of surplus, obtain mixture B；
S4, mix mixture A and mixture B, stirs evenly up to having the composition of Whitening, spot.
Preferably, the composition and hydroxyethyl cellulose, hyaluronic acid, glycerine, fourth two with Whitening, spot of preparation
Alcohol, methyl hydroxybenzoate, trehalose, collagen, 2- bromo- 2- nitropropanes -1,3- glycol, essence and deionized water are according to quality
Than for 3：0.25：0.05：3：3： 0.1：1：0.5：0.1：0.1：88.9 are prepared by mixing into the facial mask with Whitening, spot effect
Essence.
Preferably, bromo- 2- nitropropane -1 of 2- in the component of the facial mask essence with Whitening, spot effect of preparation,
3- glycol can wait quality to be substituted for the different Anthelvet ketone of methyl chloride.
Preferably, the preparation method of the facial mask essence with Whitening, spot effect is：Deionized water, ethoxy is fine
Dimension element, hyaluronic acid and glycerine dissolve by heating, and obtain mixture C, and butanediol and methyl hydroxybenzoate are dissolved by heating, obtain mixture D,
Mixture C and mixture D are mixed again, obtain mixture E, and sequentially added under agitation into mixture E after cooling
Bromo- 2- nitropropanes -1, the 3- glycol of composition, trehalose, collagen, 2- or the different Anthelvet of methyl chloride of Whitening, spot
Ketone, essence, stir to obtain the final product.
The composition of the Whitening, spot of the present invention, its dominant mechanism be by itself and junket ammonia enzyme directly in conjunction with and resistance
The oxidation of disconnected tyrosinase and DOPA, accelerates the decomposition and excretion of melanin, can effectively inhibit the tyrosine in skin
The activity of enzyme, blocks the formation of melanin, so as to fulfill nti-freckle, whitening effect, and the gold nanorods in inventive formulation
Absworption peak in 650~1100nm, both can absorb visible ray on daytime, the injury that resistance ultraviolet forms skin can also
Absorb the radiation of night human body itself, thus reach round-the-clock 24 it is small when beauty and skin care the effect of, and nanogold is bar-shaped is better than ball
The other shapes such as shape, square, nanometer gold bar can both ends produce local electric microfield, formation carries local electric microfield, and releasing office
Portion's heat with the microcirculation of physical stimulation skin, can thoroughly clean the dirt of skin accumulation, promote the metabolism of skin, increase
Strong cell viability and elasticity of skin, effectively suppress human body oxidizing process, delay wrinkle to produce, delaying senility phenomenon, maintenance is damaged
Skin, the composition of Whitening, spot proposed by the present invention can be applied to exploitation with light spot, white-skinned face function Essence or its
In the cosmetics of downstream, in addition, the composition toxicity of Whitening, spot proposed by the present invention is low, meets cosmetics laws and regulations requirement,
The deficiency of existing product is overcome, can meet the active demand of the yellow largely with color spot and needs whitening.
Embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment one
A kind of composition with Whitening, spot proposed by the present invention, includes the raw material of following percentage by weight：Hyalomitome
Sour sodium 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract 2%, Jasminum officinale Linn extract 1%, daisy
Flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer gold bar 8%, VC- ethylethers 10%, α -
Ursin 5%, butanediol 15%, calamine 20%, didextrose base gallate 10%；
Its preparation method comprises the following steps：
S1, according to Sodium Hyaluronate 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract
2%, Jasminum officinale Linn extract 1%, daisy flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer
Golden rod 8%, VC- ethylethers 10%, alpha-arbutin 5%, butanediol 15%, calamine 20%, didextrose base gallate 10% weigh
Each raw material, it is spare；
S2, by Sodium Hyaluronate, proline, hamamelis extract, Rosa centifolia flower extract, Jasminum officinale Linn extract,
Daisy flower extract, niacinamide, yeast extract, oligopeptides -1, nanometer gold bar, VC- ethylethers, alpha-arbutin, didextrose base Gallate
Acid and the mixing of part butanediol, stirring and dissolving obtains mixture A, spare；
Calamine, be dispersed in the butanediol of surplus by S3, obtains mixture B；
S4, mix mixture A and mixture B, stirs evenly up to having the composition of Whitening, spot.
Embodiment two
A kind of composition with Whitening, spot proposed by the present invention, includes the raw material of following percentage by weight：Hyalomitome
Sour sodium 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract 2%, Jasminum officinale Linn extract 1%, daisy
Flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer gold bar 8%, VC- ethylethers 10%, α -
Ursin 15%, butanediol 10%, calamine 15%, didextrose base gallate 10%；
Its preparation method comprises the following steps：
S1, according to Sodium Hyaluronate 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract
2%, Jasminum officinale Linn extract 1%, daisy flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer
Golden rod 8%, VC- ethylethers 10%, alpha-arbutin 15%, butanediol 10%, calamine 15%, didextrose base gallate 10% claim
Each raw material is taken, it is spare；
S2, by Sodium Hyaluronate, proline, hamamelis extract, Rosa centifolia flower extract, Jasminum officinale Linn extract,
Daisy flower extract, niacinamide, yeast extract, oligopeptides -1, nanometer gold bar, VC- ethylethers, alpha-arbutin, didextrose base Gallate
Acid and the mixing of part butanediol, stirring and dissolving obtains mixture A, spare；
Calamine, be dispersed in the butanediol of surplus by S3, obtains mixture B；
S4, mix mixture A and mixture B, stirs evenly up to having the composition of Whitening, spot.
Comparative example one
A kind of composition with Whitening, spot proposed by the present invention, includes the raw material of following percentage by weight：Hyalomitome
Sour sodium 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract 2%, Jasminum officinale Linn extract 1%, daisy
Flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer gold bar 8%, VC- ethylethers 3%, α-bear
Fruit glycosides 1%, butanediol 25%, calamine 30%, didextrose base gallate 1%；
Its preparation method comprises the following steps：
S1, according to Sodium Hyaluronate 4%, proline-4 %, hamamelis extract 3%, Rosa centifolia flower extract
2%, Jasminum officinale Linn extract 1%, daisy flower extract 1%, niacinamide 8%, yeast extract 4%, oligopeptides -1 5%, nanometer
Golden rod 8%, VC- ethylethers 3%, alpha-arbutin 1%, butanediol 25%, calamine 30%, didextrose base gallate 1% weigh respectively
Raw material, it is spare；
S2, by Sodium Hyaluronate, proline, hamamelis extract, Rosa centifolia flower extract, Jasminum officinale Linn extract,
Daisy flower extract, niacinamide, yeast extract, oligopeptides -1, nanometer gold bar, VC- ethylethers, alpha-arbutin, didextrose base Gallate
Acid and the mixing of part butanediol, stirring and dissolving obtains mixture A, spare；
Calamine, be dispersed in the butanediol of surplus by S3, obtains mixture B；
S4, mix mixture A and mixture B, stirs evenly up to having the composition of Whitening, spot.
The composition of Whitening, spot prepared by above-described embodiment one, embodiment two and comparative example one be respectively adopted as
Lower section method is prepared into the facial mask essence with Whitening, spot effect, and concrete operations are as follows：First according to the composition of Whitening, spot
With hydroxyethyl cellulose, hyaluronic acid, glycerine, butanediol, methyl hydroxybenzoate, trehalose, collagen, the bromo- 2- nitros third of 2-
The mass ratio of alkane -1,3- glycol, essence and deionized water is 3：0.25：0.05：3：3：0.1：1：0.5： 0.1：0.1：88.9
Raw material is weighed, then deionized water, hydroxyethyl cellulose, hyaluronic acid and glycerine are dissolved by heating, mixture C is obtained, by fourth two
Alcohol and methyl hydroxybenzoate dissolve by heating, and obtain mixture D, then mixture C and mixture D are mixed, and obtain mixture E, and in cooling
Sequentially add the bromo- 2- nitre of composition, trehalose, collagen, 2- of Whitening, spot into mixture E under agitation afterwards
Base propane -1,3- glycol, essence, stir up into the facial mask essence with Whitening, spot effect, then select
30 women triers, as the experiment crowd of the present invention, 3 groups of experiment point, every group of 10 people, the 1st group is made using embodiment one
Standby facial mask essence, the 2nd group of facial mask essence prepared using embodiment two, the 3rd group of facial mask prepared using comparative example one
Essence, service life is that the Whitening, spot effect of experiment crowd is counted after 1 month, 1 month, as a result as follows：
Statistical result showed, facial mask essence prepared by embodiment one, embodiment two and comparative example one are respectively provided with certain
Whitening, spot effect, and the Whitening, spot effect of embodiment one and the facial mask essence of the preparation of embodiment two is better than comparative example one
The facial mask essence of preparation.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited to
This, any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme
And its inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (10)
1. a kind of composition with Whitening, spot, it is characterised in that include the raw material of following percentage by weight：Moisturizer 1%
~10%, antiallergic is releived agent 1%~10%, and niacinamide 1%~10%, compact anti wrinkling agent 1%~10%, and nanometer gold bar 1%~
10%, VC- ethylether 3%~15%, alpha-arbutin 0.5%~5.0%, solvent filling reinforcing agent 14%~55%, didextrose
Base gallate 3.0%~15%, above-mentioned raw materials summation are 100%.
2. a kind of composition with Whitening, spot according to claim 1, it is characterised in that the moisturizer is transparent
The combination of matter acid sodium and proline.
3. a kind of composition with Whitening, spot according to claim 1, it is characterised in that antiallergic agent of releiving is
The combination of hamamelis extract, Rosa centifolia flower extract, Jasminum officinale Linn extract and daisy flower extract.
4. a kind of composition with Whitening, spot according to claim 1, it is characterised in that the anti wrinkling agent that compacts is
The combination of yeast extract and oligopeptides -1.
A kind of 5. composition with Whitening, spot according to claim 1, it is characterised in that the nanometer gold bar it is straight
6~8nm of footpath, longitudinal plasmon absorption peak scope are 650~1100nm, surface Raman enhancement correspond to draw ratio for 2~
10。
A kind of 6. composition with Whitening, spot according to claim 1, it is characterised in that the solvent filling enhancing
Agent is mixed by butanediol and calamine.
A kind of 7. composition with Whitening, spot according to claim 1, it is characterised in that its preparation method include with
Lower step：
S1, according to moisturizer 1%~10%, antiallergic is releived agent 1%~10%, and niacinamide 1%~10%, compact anti wrinkling agent 1%
~10%, nanometer gold bar 1%~10%, VC- ethylethers 1.5%~2.5%, alpha-arbutin 0.5%~5.0%, solvent filling
Reinforcing agent 14%~55%, didextrose base gallate 3.0%~15%, above-mentioned raw materials summation weighs each raw material for 100%, spare；
S2, moisturizer, antiallergic releived agent, niacinamide, the anti wrinkling agent that compacts, nanometer gold bar, VC- ethylethers, alpha-arbutin and molten
Matchmaker fills the part butanediol mixing in reinforcing agent, and stirring and dissolving obtains mixture A, spare；
S3, by solvent fill reinforcing agent in calamine be dispersed in the butanediol of surplus, obtain mixture B；
S4, mix mixture A and mixture B, stirs evenly up to having the composition of Whitening, spot.
A kind of 8. composition with Whitening, spot according to claim 1, it is characterised in that preparation have whitening it is light
The composition of spot and hydroxyethyl cellulose, hyaluronic acid, glycerine, butanediol, methyl hydroxybenzoate, trehalose, collagen, 2- are bromo-
2- nitropropanes -1,3- glycol, essence and deionized water are 3 according to mass ratio：0.25：0.05：3：3：0.1：1：0.5：0.1：
0.1：88.9 are prepared by mixing into the facial mask essence with Whitening, spot effect.
A kind of 9. composition with Whitening, spot according to claim 8, it is characterised in that preparation have whitening it is light
Bromo- 2- nitropropanes -1, the 3- glycol of 2- can wait quality to be substituted for the different thiophene of methyl chloride in the component of the facial mask essence of spot effect
Imidazolone.
10. a kind of composition with Whitening, spot according to claim 8 or claim 9, it is characterised in that there is Whitening, spot
The preparation method of the facial mask essence of effect is：Deionized water, hydroxyethyl cellulose, hyaluronic acid and glycerine are dissolved by heating,
Mixture C is obtained, butanediol and methyl hydroxybenzoate are dissolved by heating, obtains mixture D, then mixture C and mixture D are mixed, is obtained mixed
Compound E, and the composition, trehalose, collagen egg of Whitening, spot are sequentially added after cooling into mixture E under agitation
In vain, bromo- 2- nitropropanes -1, the 3- glycol of 2- or the different Anthelvet ketone of methyl chloride, essence, stir to obtain the final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711194152.XA CN107929119A (en) | 2017-11-24 | 2017-11-24 | A kind of composition with Whitening, spot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711194152.XA CN107929119A (en) | 2017-11-24 | 2017-11-24 | A kind of composition with Whitening, spot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107929119A true CN107929119A (en) | 2018-04-20 |
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ID=61948821
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711194152.XA Pending CN107929119A (en) | 2017-11-24 | 2017-11-24 | A kind of composition with Whitening, spot |
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Cited By (7)
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| CN109431831A (en) * | 2018-12-26 | 2019-03-08 | 郑州科斗科技有限公司 | A kind of gold nano-negative ion facial mask liquid of Whitening, spot, facial mask and preparation method thereof |
| CN109464366A (en) * | 2019-01-02 | 2019-03-15 | 吉林大学 | A kind of composition for removing skin pigmentation and its preparation method and application |
| CN110384623A (en) * | 2019-08-20 | 2019-10-29 | 广州博今生物科技有限公司 | One kind is spraying according to safe and comfortable draft is protected |
| CN110721104A (en) * | 2019-10-31 | 2020-01-24 | 泉后(广州)生物科技研究院有限公司 | Whitening cream and preparation method thereof |
| CN111388377A (en) * | 2020-04-22 | 2020-07-10 | 广州峻美生物科技有限公司 | Nicotinamide stock solution and preparation method thereof |
| CN112472623A (en) * | 2019-10-12 | 2021-03-12 | 广东丸美生物技术股份有限公司 | Essence with whitening and repairing effects and preparation method and application thereof |
| CN116751257A (en) * | 2023-08-14 | 2023-09-15 | 江苏华肌生物科技有限公司 | Rosa polypeptide and application thereof in skin whitening and moisturizing medicines or cosmetics |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109431831A (en) * | 2018-12-26 | 2019-03-08 | 郑州科斗科技有限公司 | A kind of gold nano-negative ion facial mask liquid of Whitening, spot, facial mask and preparation method thereof |
| CN109464366A (en) * | 2019-01-02 | 2019-03-15 | 吉林大学 | A kind of composition for removing skin pigmentation and its preparation method and application |
| CN110384623A (en) * | 2019-08-20 | 2019-10-29 | 广州博今生物科技有限公司 | One kind is spraying according to safe and comfortable draft is protected |
| CN112472623A (en) * | 2019-10-12 | 2021-03-12 | 广东丸美生物技术股份有限公司 | Essence with whitening and repairing effects and preparation method and application thereof |
| CN110721104A (en) * | 2019-10-31 | 2020-01-24 | 泉后(广州)生物科技研究院有限公司 | Whitening cream and preparation method thereof |
| CN111388377A (en) * | 2020-04-22 | 2020-07-10 | 广州峻美生物科技有限公司 | Nicotinamide stock solution and preparation method thereof |
| CN116751257A (en) * | 2023-08-14 | 2023-09-15 | 江苏华肌生物科技有限公司 | Rosa polypeptide and application thereof in skin whitening and moisturizing medicines or cosmetics |
| CN116751257B (en) * | 2023-08-14 | 2023-10-20 | 江苏华肌生物科技有限公司 | Rosa polypeptide and application thereof in skin whitening and moisturizing medicines or cosmetics |
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