CN107928782B - Electrode device for inactivating tumor cells in esophageal wall and using method thereof - Google Patents

Abstract

The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in the esophagus wall and a method for using the same. The lead wire of the ring electrode passes through the upper part of the push tube and is connected with the power distribution controller on the workbench; the purpose of the present invention is to provide an electrode device for inactivating tumor cells in the esophagus wall and a method of using the same. The electrode is used as a working part, and the push tube is used as the delivery medium, and the characteristic equipment can be used to inactivate the tumor cells in the surrounding esophageal wall by the electric field generated by the DC high voltage.

Description

Electrode device for inactivating tumor cells in esophageal wall and method of using the same

technical field

The invention relates to the field of medical equipment, in particular to an electrode device for inactivating tumor cells in the esophagus wall and a method for using the same.

Background technique

Irreversible electroporation (IRE) is a new soft tissue ablation technology that uses ultra-short high-voltage direct current (up to 3 kV) to generate multiple nano-scale micropores in the cell membrane of cells in ablated tissue, irreversibly. Disrupting the intracellular homeostasis, induces apoptosis and ultimately death.

The device of irreversible electroporation is mainly composed of a power distribution controller composed of a high-voltage pulse power supply and an oscilloscope, and electrodes.

Electrodes are used to apply DC high voltage to tissue cells. At present, the widely used electrodes are needle electrodes. The electrode needles are inserted into the tissue to form a high-voltage electric field around it, that is, the ablation zone, thereby inactivating tissue cells in a specific area. In some animal experiments, plate electrodes are used. However, both needle electrodes and plate electrodes are only used for clinical treatment or experiments of solid tumor tissues such as liver cancer, pancreatic cancer, prostate cancer and kidney cancer. Cancer, a hollow organ tumor, cannot be treated with either electrode.

SUMMARY OF THE INVENTION

The purpose of the present invention is to provide an electrode device for inactivating tumor cells in the esophagus wall and a method of using the same. The ring electrode is used as the working part, and the push tube is used as the delivery medium. The electric field generated by the DC high voltage inactivates tumor cells in the surrounding esophageal wall.

In order to achieve the above purpose, the technical scheme adopted in the present invention is as follows: an electrode device for inactivating tumor cells in the esophagus wall, which comprises a worktable and a push tube, wherein a ring electrode is matched with the push tube, and the The wire of the ring electrode goes out of the upper part of the push tube and is connected with the power distribution controller on the workbench.

Further, an insulating weight block is arranged in the annular electrode, and the upper part of the weight block is connected with a pull pipe which penetrates the upper part of the push pipe.

Further, the annular electrode (10) is provided with a deflating airbag (8), the weight (9) is arranged in the deflating airbag (8), and the pulling tube is connected to the deflating airbag (8). 8) A connected inflatable tube (5), the inflatable tube (5) communicates with the air pump (3) provided on the workbench (1), and the wire (6) and the inflatable tube (5) pass through the clamp ( 7) Tie together.

Further, the part of the upper part of the inflatable tube (5) beyond the push tube (4) is fixedly connected with a push card position fixing seat (14), and the upper part of the push tube (4) is sleeved with a pusher with an opening in the middle. A card seat (11), the upper part of the push card seat (11) and the lower part of the push card seat fixing seat (14) are provided with a push card seat sleeve (12) with matching positions, and the card seat sleeve is pushed up and down. A push-and-lock rod (13) is inserted between (12).

Another technical solution of the present invention is: a method for using an electrode device for inactivating tumor cells in the esophagus wall, characterized in that it includes the following steps:

①. Prepare the device first. At the beginning, there is a push card position inserted between the upper and lower push card position sleeves;

②. Push the push tube prepared in step ① from the mouth along the esophagus to the tumor site of the esophageal wall;

③. Lift up the push card position fixing base, then remove the push card position rod, and then lower the push card position fixing base under the gravity of the heavy block, and at the same time lift the push tube to a certain height and keep it stable , so that the ring electrode is separated from the esophageal tube to cooperate with the tumor site;

④. Inflate the air bag through the air pump, so that the ring electrode can be deformed to a certain extent, so that the ring electrode can touch the tumor part of the esophageal wall;

⑤. The high-voltage direct current is generated by the power distribution controller, so that a strong electric field is formed around the ring electrode, and then the tumor part of the esophageal wall is inactivated.

The beneficial effects of the present invention are:

1. The ring electrode is used as the working part, the push tube is used as the delivery medium, and the characteristic equipment is used to inactivate the tumor cells in the surrounding esophageal wall by the electric field generated by the DC high voltage.

2. The design of the insulating weight can not only push the ring electrode to the inner wall of the esophagus together with the push tube, but also generate relative displacement with the push tube, so that the ring electrode can directly interact with the tumor part.

3. The design of expanding the balloon can make the ring electrode deform to a certain degree, and then the ring electrode can directly contact the tumor tissue in the esophagus wall, so as to improve the effect of inactivation treatment.

4. The structural design of the push card position sleeve and the push card position rod can ensure that the ring electrode can be pushed synchronously with the push tube during the push, which ensures the efficiency of the push, and does not affect the subsequent relative movement of the two.

Description of drawings

FIG. 1 is a schematic structural diagram of an electrode device for inactivating tumor cells in the esophageal wall.

FIG. 2 is a partial enlarged view of A in FIG. 1 .

FIG. 3 is a partial enlarged view of B in FIG. 1 .

The text labels shown in the figure are: 1. Workbench; 2. Power distribution controller; 3. Air pump; 4. Push tube; 5. Inflatable tube; 6. Conductor; 7. Clamp; 9. Heavy block; 10. Ring electrode; 11. Pushing the card seat; 12. Pushing the card position sleeve; 13. Pushing the card position rod; 14. Pushing the card position fixing seat.

Detailed ways

In order to make those skilled in the art better understand the technical solutions of the present invention, the present invention will be described in detail below with reference to the accompanying drawings. The description in this part is only exemplary and explanatory, and should not have any limiting effect on the protection scope of the present invention. .

As shown in Fig. 1-Fig. 3, the specific structure of the present invention is: an electrode device for inactivating tumor cells in the esophagus wall, which comprises a workbench 1 and a push tube 4, and the push tube 4 cooperates with the inside of the push tube 4. There is a ring electrode 10 , and the wire 6 of the ring electrode 10 passes through the upper part of the push tube 4 and is connected to the power distribution controller 2 on the workbench 1 .

Preferably, the ring electrode 10 is provided with an insulating weight block 9 , and the upper part of the weight block 9 is connected with a pull pipe penetrating the upper part of the push pipe 4 .

Preferably, the annular electrode 10 is provided with a deflating airbag 8 , the weight 9 is provided in the deflating airbag 8 , the pulling tube is an inflation tube 5 communicated with the deflating airbag 8 , and the The inflatable tube 5 is communicated with the air pump 3 set on the workbench 1, and the wire 6 and the inflatable tube 5 are tied together by a clamp 7.

Preferably, the upper part of the inflatable pipe 5 beyond the push pipe 4 is fixedly connected with a push card position fixing seat 14, and the upper part of the push pipe 4 is sleeved with a push card seat 11 with an opening in the middle. The upper part of the push card seat 11 and the lower part of the push card seat fixing seat 14 are provided with a push card position sleeve 12 with matching positions, and a push card position rod 13 is inserted between the upper and lower push card position sleeves 12 .

A method for using an electrode device for inactivating tumor cells in an esophageal wall, comprising the following steps:

①. Prepare the device first. At the beginning, there is a push card position inserted between the upper and lower push card position sleeves;

②. Push the push tube prepared in step ① from the mouth along the esophagus to the tumor site of the esophageal wall;

③. Lift up the push card position fixing base, then remove the push card position rod, and then lower the push card position fixing base under the gravity of the heavy block, and at the same time lift the push tube to a certain height and keep it stable , so that the ring electrode is separated from the esophageal tube to cooperate with the tumor site;

④. Inflate the air bag through the air pump, so that the ring electrode can be deformed to a certain extent, so that the ring electrode can touch the tumor part of the esophageal wall;

⑤. The high-voltage direct current is generated by the power distribution controller, so that a strong electric field is formed around the ring electrode, and then the tumor part of the esophageal wall is inactivated.

It should be noted that, herein, the terms "comprising", "comprising" or any other variation thereof are intended to encompass non-exclusive inclusion, such that a process, method, article or device comprising a series of elements includes not only those elements, It also includes other elements not expressly listed or inherent to such a process, method, article or apparatus.

Specific examples are used herein to illustrate the principles and implementations of the present invention, and the descriptions of the above examples are only used to help understand the method and the core idea of the present invention. The above are only the preferred embodiments of the present invention. It should be pointed out that due to the limited expression of words, there are objectively unlimited specific structures. For those of ordinary skill in the art, without departing from the principles of the present invention However, some improvements, modifications or changes can also be made, and the above-mentioned technical features can also be combined in an appropriate manner; these improvements, modifications, or combinations, or the concept and technical solutions of the invention are directly applied to other occasions without improvement. should be regarded as the protection scope of the present invention.

Claims (1)

1. The electrode device for inactivating tumor cells in an esophageal wall is characterized by comprising a workbench (1) and a pushing tube (4), wherein an annular electrode (10) is matched in the pushing tube (4), a lead (6) of the annular electrode (10) penetrates out of the upper part of the pushing tube (4) and is connected with a power distribution controller (2) on the workbench (1), an insulating heavy block (9) is arranged in the annular electrode (10), the upper part of the heavy block (9) is connected with a pull tube penetrating out of the upper part of the pushing tube (4), a propping air bag (8) is arranged in the annular electrode (10), the heavy block (9) is arranged in the propping air bag (8), the pull tube is an inflating tube (5) communicated with the propping air bag (8), the inflating tube (5) is communicated with an air pump (3) arranged on the workbench (1), wire (6) and gas tube (5) tie up together through clamp (7), gas tube (5) upper portion surpass the position of propelling movement pipe (4) and linked firmly propelling movement screens rigid coupling seat (14), the upper portion of propelling movement pipe (4) cup joint middle part open-ended propelling movement screens seat (11), the upper portion of propelling movement screens seat (11) and the lower part of propelling movement screens rigid coupling seat (14) be provided with propelling movement screens cover (12) that the position matches, and plug bush has propelling movement screens pole (13) between upper and lower propelling movement screens cover (12).

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