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CN107854588A - A kind of Chinese medicine composition for treating fatty liver and preparation method thereof - Google Patents

A kind of Chinese medicine composition for treating fatty liver and preparation method thereof Download PDF

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Publication number
CN107854588A
CN107854588A CN201711314716.9A CN201711314716A CN107854588A CN 107854588 A CN107854588 A CN 107854588A CN 201711314716 A CN201711314716 A CN 201711314716A CN 107854588 A CN107854588 A CN 107854588A
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parts
chinese medicine
stir
fatty liver
medicine composition
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代立新
代哲尘
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Tangyin County Red Star Biology Co Ltd
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Tangyin County Red Star Biology Co Ltd
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
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Abstract

Patent of the present invention discloses a kind of Chinese medicine composition for treating fatty liver and preparation method thereof, wherein, the Chinese medicine material that the Chinese medicine composition is matched by following parts by weight forms:10 15 parts of radix bupleuri, 10 20 parts of stir-baked FRUCTUS TOOSENDAN, 20 30 parts of charred FRUCTUS CRATAEGI, 10 20 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 10 30 parts of the membrane of a chicken's gizzard, 15 25 parts of cassia seed, 10 15 parts of Herba Lycopi, 10 15 parts of rhizoma pinellinae praeparata, 6 10 parts of Radix Codonopsis, 10 15 parts of wrinkled giant hyssop, 10 20 parts of Snakegourd Fruit, 10 15 parts of peach kernel, 10 20 parts of safflower, 10 15 parts of corydalis tuber, 10 20 parts of rhizoma cyperi, 10 15 parts of Ligusticum wallichii, 69 parts of excrementum pteropi.The Chinese medicine composition of present invention treatment fatty liver, compatibility is reasonable, has no toxic side effect, and can fundamentally treat fatty liver, efficacy stability is uneasy to recur, cheap.

Description

A kind of Chinese medicine composition for treating fatty liver and preparation method thereof
Technical field
Patent of the present invention is related to the technical field for treating fatty liver, especially a kind of Chinese medicine composition for treating fatty liver and Its preparation method, belong to the field of Chinese medicines.
Background technology
Fatty liver refers to due to the excessive lesion of fat accumulation in liver cell caused by a variety of causes, is a kind of common liver Dirty pathological change, rather than a kind of independent disease.The health of the positive serious threat people of fatty liver disease, turn into be only second to it is viral The second largest hepatopathy of hepatitis, the incidence of disease are constantly raising, and age of onset rejuvenation increasingly.Containing a small amount of in normal human liver tissue Fat, such as triglycerides, phosphatide, glycolipid and cholesterol, its weight is about the 3%~5% of liver weight, if intrahepatic fat Accumulation is too many, more than liver weight 5% or when histologically liver cell more than 50% has steatosis, so that it may be referred to as fat Liver.In clinical manifestation, fatty liver is generally divided into alcoholic fatty liver and the major class of NASH two.According to steatosis In the scope that liver involves, can be divided into again it is light, in, weigh three types, quilt when usual fat content exceedes the 5%~10% of liver weight It is considered as mild fatty liver, is moderate fatty liver more than 10%~25%, is severe fatty liver more than 25%.
The diverse clinical manifestations of fatty liver, mild fatty liver is more to be chanced on without clinical symptoms, patient when being more than physical examination.It is tired Weary sense is the most common subjective symptoms of Patients with Fatty Liver, but with the order of severity non-correlation of Histological injury.In, severe fat Liver has the performance of similar chronic hepatitis, can there is poor appetite, lassitude and weak, Nausea and vomiting, hepatic region or upper right abdomen secret anguish etc..When Intrahepatic fat deposition it is excessive when, can make liver envelope expansion, hepatic ligament drawing, and cause upper right abdomen have an intense pain or tenderness, heating, White blood cell count(WBC) increases, and mistaken diagnosis makees laparotomy ventrotomy for acute abdomen.In addition, Patients with Fatty Liver also often has glossitis, angular stomatitis, skin The change of the peripheral neuritis such as ecchymosis, numb limb, meropresthesia.Small number of patients also can have hemorrhage of digestive tract, gum to go out Blood, nosebleed epistaxis etc..Severe fatty liver patient can have seroperitoneum and edema of lower extremity, electrolyte disturbance such as low sodium and low potassium mass formed by blood stasis etc., Fatty liver performance is various, has certain difficulty during diagnosis, can do liver biopsy and make a definite diagnosis.
At present, the treatment of fatty liver is directed to still to remove the cause of disease, Cure the Primary Disease and adhere to based on reasonable diet, Medicine only plays auxiliary therapeutic action.The medicine for being clinically used to treat fatty liver at present is broadly divided into hypolipidemic, liver-protecting fat-dropping Medicine and traditional Chinese medicine, Western medicine is often from liver cell, degreasing medicine and antioxidant etc. is protected, although these Western medicine are quick, Often cure the symptoms, not the disease, cause Relapse rate.
The content of the invention
For the problems of the prior art, the invention aims to provide a kind of Chinese medicine composition for treating fatty liver and Its preparation method, the Chinese medicine composition prepared by this method is safe and reliable, has no toxic side effect, and the property of medicine is stable, cheap, knot Close monarch make up a prescription mechanism carry out compatibility, there is the effect of fine to fatty liver.
In order to achieve the above object, the technical scheme is that:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:Radix bupleuri 10-15 Part, stir-baked FRUCTUS TOOSENDAN 10-20 parts, charred FRUCTUS CRATAEGI 20-30 parts, stir-baked MASSA FERMENTATA MEDICI-NALIS 10-20 parts, the membrane of a chicken's gizzard 10-30 parts, cassia seed 15-25 parts, pool Blue 10-15 parts, rhizoma pinellinae praeparata 10-15 parts, Radix Codonopsis 6-10 parts, wrinkled giant hyssop 10-15 parts, Snakegourd Fruit 10-20 parts, peach kernel 10-15 parts, safflower 10-20 parts, corydalis tuber 10-15 parts, rhizoma cyperi 10-20 parts, Ligusticum wallichii 10-15 parts, excrementum pteropi 6-9 parts.
As preferable, the Chinese medicine composition for the treatment of fatty liver of the present invention, in being matched by following parts by weight Medicine raw material forms:Radix bupleuri 12-14 parts, stir-baked FRUCTUS TOOSENDAN 12-18 parts, charred FRUCTUS CRATAEGI 22-28 parts, stir-baked MASSA FERMENTATA MEDICI-NALIS 12-18 parts, the membrane of a chicken's gizzard 12- 28 parts, cassia seed 17-23 parts, Herba Lycopi's 12-14 parts, rhizoma pinellinae praeparata 12-14 parts, Radix Codonopsis 7-9 parts, wrinkled giant hyssop 12-14 parts, Snakegourd Fruit 12-18 Part, peach kernel 12-14 parts, safflower 12-18 parts, corydalis tuber 12-14 parts, rhizoma cyperi 12-18 parts, Ligusticum wallichii 12-14 parts, excrementum pteropi 7-8 parts.
As preferable, the Chinese medicine composition for the treatment of fatty liver of the present invention, in being matched by following parts by weight Medicine raw material forms:11 parts of radix bupleuri, 11 parts of stir-baked FRUCTUS TOOSENDAN, 21 parts of charred FRUCTUS CRATAEGI, 11 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard 11,16 parts of cassia seed, pool It is blue 11 parts, 11 parts of rhizoma pinellinae praeparata, 6 parts of Radix Codonopsis, 11 parts of wrinkled giant hyssop, 11 parts of Snakegourd Fruit, 11 parts of peach kernel, 11 parts of safflower, 11 parts of corydalis tuber, rhizoma cyperi 11 Part, 11 parts of Ligusticum wallichii, 6 parts of excrementum pteropi.
As preferable, the Chinese medicine composition for the treatment of fatty liver of the present invention, in being matched by following parts by weight Medicine raw material forms:13 parts of radix bupleuri, 16 parts of stir-baked FRUCTUS TOOSENDAN, 26 parts of charred FRUCTUS CRATAEGI, 16 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 26 parts of the membrane of a chicken's gizzard, 22 parts of cassia seed, 13 parts of Herba Lycopi, 13 parts of rhizoma pinellinae praeparata, 8 parts of Radix Codonopsis, 13 parts of wrinkled giant hyssop, 16 parts of Snakegourd Fruit, 13 parts of peach kernel, 16 parts of safflower, 13 parts of corydalis tuber, rhizoma cyperi 17 parts, 13 parts of Ligusticum wallichii, 8 parts of excrementum pteropi.
Present invention simultaneously provides a kind of preparation method of the Chinese medicine composition for the treatment of fatty liver as described above, including it is as follows Step:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it is put into after well mixed in marmite, into marmite 1000-1500ml water is added, soaks 30-60 minutes;
2) after boiling by intense fire, being heated 30 minutes with slow fire, after temperature slightly drops, take filtrate, the dregs of a decoction in marmite are standby, and Filtrate is poured into container, obtains first time decoction;
3) hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then slow fire heating About 30 minutes, after temperature is down to room temperature, filtrate is taken, obtains second of decoction;
4) it well-done decoction will be put into same container, and be well mixed twice, it is filling close after obtained decoction is sterilized Envelope, obtains Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction:Take in three times within 1 day.Also can be 1 time Property decoct the dose of 2 days, filling and sealing after obtained decoction is sterilized, refrigeration, first micro- heating when taking.This Chinese traditional medicine composition Thing can also be prepared into powder capsule, and concrete scheme is as follows:
The preparation method of the Chinese medicine composition for the treatment of fatty liver as described above, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it will be well mixed after the medicinal material drying of acquirement;
2) medicinal material after being well mixed in step 1) is ground into medicinal powder;
3) medicinal powder of step 2) is crossed into 500-800 mesh sieves and traditional Chinese medicine powder is made;
4) traditional Chinese medicine powder for obtaining step 3) is put sterilizes 1 hour under ultraviolet light, obtains Chinese medicine composition medicinal powder;
5) Chinese medicine composition medicinal powder made from step 4) is fitted into capsulae vacuus and capsule is made, obtain Chinese medicine composition glue Capsule.
Further, the granularity of the traditional Chinese medicine powder obtained in the preparation method step 3) is 600 mesh.
The Chinese medicine composition of the present invention has no toxic side effect, and therapeutic effect is good and stably, treats both principal and secondary aspect of disease, uneasy to recur, price It is cheap.
The Chinese medicine composition can be prepared into the diversified forms such as Chinese medicinal tablet, particle, traditional Chinese medicine pill, electuary, be not limited to Decoction and capsule, suitable for a variety of therapeutic modalities, application method.
The pharmacology of all kinds of Chinese medicines is as follows in the present invention:
Radix bupleuri:Taste:It is bitter;Property:It is cool;Enter courage, Liver Channel;Function:It is soothing the liver in inducing diaphoresis, rising Yang;Cure mainly:Cold, fever, fever and chills Contact, distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus.
Stir-baked FRUCTUS TOOSENDAN:Taste:It is bitter;Property:It is cold;Enter liver, small intestine, bladder warp;Function:Except damp and hot, clearing away the liver-fire, analgesic, desinsection;It is main Control:Pyretic epigastralgia, hypochondriac pain, colic, abdominal pain due to enterositosis, favus of the scalp.
Stir-baked FRUCTUS CRATAEGI:Taste:Acid;Property:Temperature;Enter spleen, stomach, Liver Channel;Function:Promoting digestion and removing indigestion;Cure mainly:Insufficiency of the spleen food stagnation, poor appetite, God is tired weak.
Stir-baked MASSA FERMENTATA MEDICI-NALIS:Taste:It is sweet, pungent;Property:Temperature;Enter spleen, stomach;Function:Temperature food and stomach;Cure mainly:Eating accumulation.
The membrane of a chicken's gizzard:Taste:It is sweet;Property:It is flat;Enter spleen, stomach;Function:Stomach strengthening and digestion promoting, arresting seminal emission;Cure mainly:Dyspepsia, vomit Vomiting and diarrhoea dysentery, infantile malnutrition, the enuresis, seminal emission.
Cassia seed:Taste:It is sweet, bitter;Property:It is cool;Enter liver and kidney channel;Function:Heat-clearing improving eyesight, relax bowel;Cure mainly:The puckery pain of hot eyes, The more tears of photophobia, dizziness of having a headache, mesh secretly fail to understand, constipation.
Herba Lycopi:Taste:It is pungent, bitter;Property:Temperature;Enter spleen, Liver Channel;Function:It is promoting blood circulation and removing blood stasis, line water detumescence;Cure mainly:Irregular menstruation, warp Close, dysmenorrhoea, postpartum blood stasis stomachache, oedema.
Rhizoma pinellinae praeparata:Taste:It is pungent;Property:Temperature;Enter stomach, lung, the spleen channel;Function:It is eliminating dampness and eliminating phlegm;Cure mainly:Abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, Anemophlegmatic vertigo, phlegm and headache.
Radix Codonopsis:Taste:It is sweet;Property:It is flat;Enter lung, the spleen channel;Function:Tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung;Cure mainly:Spleen and lung weakness, shortness of breath Palpitaition, anorexia and loose stool, virtual asthma cough, Heat Diabetes.
Wrinkled giant hyssop:It is pungent, tepor.Enter lung, spleen, stomach.Function:Fast gas, and in, ward off dirty, clearing damp.Cure mainly:Flu summer-heat and damp, trembles with fear Heat, headache, chest gastral cavity ruffian, vomiting and diarrhea, malaria, dysentery, halitosis.
Snakegourd Fruit:Taste:It is sweet, bitter:Property:It is cold;Enter stomach, lung, large intestine channel;Function:Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, ease constipation;Cure mainly: Cough with lung heat, the turbid Huang of phlegm is thick, chest impediment and cardialgia, acute mastitis, lung carbuncle, acute appendicitis swelling and pain.
Peach kernel:Bitter, hardship, it is mild-natured, enter the heart, liver, large intestine channel.Function:Promoting blood circulation, relax bowel, it is relieving cough and asthma.It is main Control:Amenorrhea, dysmenorrhoea , wei lump in the abdomen lump in the abdomens, injury from falling down, dry constipation of intestines.
Safflower:Taste:It is pungent;Property:Temperature;Enter the heart channel of Hang-Shaoyin;Function:Invigorate blood circulation, blood stasis removing analgesic;Cure mainly:Amenorrhea, dysmenorrhoea, lochia is not OK, abdominal mass lump in the abdomen, injury from falling down, sore swell and ache curative.
Corydalis tuber:Taste:It is pungent, bitter;Property:Temperature;Enter liver, spleen, the heart channel of Hang-Shaoyin;Function:Regulating qi-flowing for relieving pain, promoting blood circulation to remove blood stasis;Cure mainly:Stomachache, pain Through, traumatic injury.
Rhizoma cyperi:Taste:It is pungent;Property:It is cold;Enter three burnt, Liver Channel;Function:Promoting qi circulation and removing obstruction in the collateral, menstruction regulating and pain relieving;Cure mainly:Stagnation of QI due to depression of the liver, chest, The side of body, abdominal distention, indigestion, chest gastral cavity ruffian, cold hernia stomachache, swollen breasts, irregular menstruation, closed dysmenorrhea.
Ligusticum wallichii:Taste:It is pungent;Property:Temperature;Enter liver, courage, the heart channel of Hang-Shaoyin;Function:Blood-activating and qi-promoting, wind-expelling pain-stopping;Cure mainly:Irregular menstruation, warp Close dysmenorrhoea, abdominal mass stomachache, chest side of body shouting pain, tumbling and swelling, headache, arthralgia pain due to rheumatism.
Excrementum pteropi:Taste:It is sweet;Property:Temperature;Enter spleen, Liver Channel;Function:Promoting blood circulation and stopping pain;Removing blood stasis and hemostasis;Disperse accumulations is detoxified;Cure mainly:The heart The all pains of abdomen vim and vigour;Women's amenorrhoea;Postpartum stasis of blood;Metrostaxis;Infantile malnutrition;Snakes and scorpions centipde-bite.
" organic conception " is had been accepted as at present, " diagnosis and treatment based on an overall analysis of the illness and the patient's condition ", " compound use ", " compound compatibility medication is such as used military forces " are the traditional Chinese medical science Most scientific maximally effective several big advantages, wherein " compound compatibility medication is such as used military forces " is the original theory of traditional Chinese medicine of very science.In The tight compatibility that each medicine is all linked with one another as arraying troops for battle in prescription is cured, is that it is better than the effective means of western medicine formula.The traditional Chinese medical science Prescription theory thinks, each prescription, not only needs to select the suitable appropriate compatibility of medicine according to etiology and pathogenesis, while should also accord with Close the prescription compatibility theory of the basic structure of prescription, i.e. " monarch, minister, help, make ", the prescription compatibility of so-called " monarch, minister, help, make ", just It is that it establishes the scientific matching on the comprehensive judgement basis to the disease interpretation of the cause, onset and process of an illness.Middle medical square is whole by too many levels, Mutiple Targets The biological mechanism of regulation is closed, therapeutic effect more more longlasting than Western medicine, that more green natural has no toxic side effect can be obtained, and it is this Curative effect is built upon on the original theoretical accurate instruction of above-mentioned traditional Chinese medical science tradition, and the present invention just have followed this principle.
Monarch drug in a prescription treats primary symptom in the side of referring to, plays the medicine of primary treatment, can use as required simply or a few taste medicines.Minister Medicine is the medicine assisted main ingredient or strengthen main ingredient effect.Adjutant is the medicine for the toxicity assisted main ingredient treatment and disease or suppress main ingredient Thing.Make the effect that medicine is the through diseased region of each medicine of guiding or each medicine of mediation.
The Chinese medicine composition for the treatment of fatty liver provided by the invention, so that with inducing diaphoresis, soothing the liver, the radix bupleuri of rising Yang is monarch drug in a prescription; With except damp and hot, clearing away the liver-fire, analgesic, the stir-baked FRUCTUS TOOSENDAN of desinsection, the stir-baked FRUCTUS CRATAEGI taste ministerial drug of promoting digestion and removing indigestion;With Jiao god of temperature food and stomach Bent, stomach strengthening and digestion promoting, the membrane of a chicken's gizzard of arresting seminal emission, heat-clearing improving eyesight, the cassia seed to relax bowel, promoting blood circulation and removing blood stasis, the pool of line water detumescence Blue, eliminating dampness and eliminating phlegm rhizoma pinellinae praeparata, tonifying middle-Jiao and Qi, the Radix Codonopsis of strengthening spleen and tonifying lung, fast gas, and in, ward off dirty, the wrinkled giant hyssop of clearing damp, heat-clearing are washed Phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, Snakegourd Fruit, the promoting blood circulation of ease constipation, relax bowel, relieving cough and asthma peach kernel, invigorate blood circulation, blood stasis removing analgesic it is red Flower, regulating qi-flowing for relieving pain, the corydalis tuber of promoting blood circulation to remove blood stasis, promoting qi circulation and removing obstruction in the collateral, the rhizoma cyperi of menstruction regulating and pain relieving, blood-activating and qi-promoting, the Ligusticum wallichii of wind-expelling pain-stopping are Adjutant;With removing blood stasis and hemostasis;The excrementum pteropi of disperse accumulations removing toxic substances is to make medicine.The Chinese medicine composition for the treatment of fatty liver provided by the invention, matches somebody with somebody 5 rationally, have no toxic side effect, can fundamentally treat fatty liver, efficacy stability is uneasy to recur, cheap.
Embodiment
Below in conjunction with embodiment, the technical scheme in the embodiment of the present invention is clearly and completely described.Obviously, Described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Based on the implementation in the present invention Example, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, is belonged to The scope of protection of the invention.
Embodiment one:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:10 parts of radix bupleuri, 10 parts of stir-baked FRUCTUS TOOSENDAN, 20 parts of charred FRUCTUS CRATAEGI, 10 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 10 parts of the membrane of a chicken's gizzard, 15 parts of cassia seed, 10 parts of Herba Lycopi, 10 parts of rhizoma pinellinae praeparata, 6 parts of Radix Codonopsis, 10 parts of wrinkled giant hyssop, 10 parts of Snakegourd Fruit, 10 parts of peach kernel, 10 parts of safflower, 10 parts of corydalis tuber, 10 parts of rhizoma cyperi, 10 parts of Ligusticum wallichii, excrementum pteropi 6 parts.
The present embodiment provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it is put into after well mixed in marmite, into marmite 1000ml water is added, is soaked 30 minutes;
2) after boiling by intense fire, being heated 30 minutes with slow fire, after temperature slightly drops, take filtrate, the dregs of a decoction in marmite are standby, and Filtrate is poured into container, obtains first time decoction;
3) hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then slow fire heating About 30 minutes, after temperature is down to room temperature, filtrate is taken, obtains second of decoction;
4) it well-done decoction will be put into same container, and be well mixed twice, it is filling close after obtained decoction is sterilized Envelope, obtains Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction:Take at twice within 1 day, it is big every time About 300ml.Also can 1 property decoct the dose of 2 days, filling and sealing after obtained decoction is sterilized, refrigeration, it is first pico- when taking plus Heat.
Embodiment two:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:11 parts of radix bupleuri, 11 parts of stir-baked FRUCTUS TOOSENDAN, 21 parts of charred FRUCTUS CRATAEGI, 11 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard 11,16 parts of cassia seed, 11 parts of Herba Lycopi, 11 parts of rhizoma pinellinae praeparata, party 6 parts of ginseng, 11 parts of wrinkled giant hyssop, 11 parts of Snakegourd Fruit, 11 parts of peach kernel, 11 parts of safflower, 11 parts of corydalis tuber, 11 parts of rhizoma cyperi, 11 parts of Ligusticum wallichii, excrementum pteropi 6 Part.
The present embodiment also provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it will be well mixed after the medicinal material drying of acquirement;
2) medicinal material after being well mixed in step 1) is ground into medicinal powder;
3) medicinal powder of step 2) is crossed into 600 mesh sieves and traditional Chinese medicine powder is made;
4) traditional Chinese medicine powder for obtaining step 3) is put sterilizes 1 hour under ultraviolet light, obtains Chinese medicine composition medicinal powder;
5):Chinese medicine composition medicinal powder made from step 4) is fitted into capsulae vacuus capsule is made, obtain Chinese medicine composition glue Capsule.
Chinese medicinal composition capsules prepared by the above method, instructions of taking are:Take in three times within 1 day, 15 grams every time (3).
Embodiment three:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:12 parts of radix bupleuri, 12 parts of stir-baked FRUCTUS TOOSENDAN, 22 parts of charred FRUCTUS CRATAEGI, 12 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 12 parts of the membrane of a chicken's gizzard, 17 parts of cassia seed, 12 parts of Herba Lycopi, 12 parts of rhizoma pinellinae praeparata, 7 parts of Radix Codonopsis, 12 parts of wrinkled giant hyssop, 12 parts of Snakegourd Fruit, 12 parts of peach kernel, 12 parts of safflower, 12 parts of corydalis tuber, 12 parts of rhizoma cyperi, 12 parts of Ligusticum wallichii, excrementum pteropi 7 parts.
The present embodiment provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it is put into after well mixed in marmite, into marmite 1200ml water is added, is soaked 45 minutes;
2) after boiling by intense fire, being heated 30 minutes with slow fire, after temperature slightly drops, take filtrate, the dregs of a decoction in marmite are standby, and Filtrate is poured into container, obtains first time decoction;
3) hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then slow fire heating About 30 minutes, after temperature is down to room temperature, filtrate is taken, obtains second of decoction;
4) it well-done decoction will be put into same container, and be well mixed twice, it is filling close after obtained decoction is sterilized Envelope, obtains Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction:Take at twice within 1 day, it is big every time About 300ml.Also can 1 property decoct the dose of 2 days, filling and sealing after obtained decoction is sterilized, refrigeration, it is first pico- when taking plus Heat.
Example IV:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:13 parts of radix bupleuri, 16 parts of stir-baked FRUCTUS TOOSENDAN, 26 parts of charred FRUCTUS CRATAEGI, 16 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 26 parts of the membrane of a chicken's gizzard, 22 parts of cassia seed, 13 parts of Herba Lycopi, 13 parts of rhizoma pinellinae praeparata, 8 parts of Radix Codonopsis, 13 parts of wrinkled giant hyssop, 16 parts of Snakegourd Fruit, 13 parts of peach kernel, 16 parts of safflower, 13 parts of corydalis tuber, 17 parts of rhizoma cyperi, 13 parts of Ligusticum wallichii, excrementum pteropi 8 parts.
The present embodiment also provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it will be well mixed after the medicinal material drying of acquirement;
2) medicinal material after being well mixed in step 1) is ground into medicinal powder;
3) medicinal powder of step 2) is crossed into 600 mesh sieves and traditional Chinese medicine powder is made;
4) traditional Chinese medicine powder for obtaining step 3) is put sterilizes 1 hour under ultraviolet light, obtains Chinese medicine composition medicinal powder;
5):Chinese medicine composition medicinal powder made from step 4) is fitted into capsulae vacuus capsule is made, obtain Chinese medicine composition glue Capsule.
Chinese medicinal composition capsules prepared by the above method, instructions of taking are:Take in three times within 1 day, 15 grams every time (3).
Embodiment five:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:14 parts of radix bupleuri, 18 parts of stir-baked FRUCTUS TOOSENDAN, 28 parts of charred FRUCTUS CRATAEGI, 18 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 28 parts of the membrane of a chicken's gizzard, 23 parts of cassia seed, 14 parts of Herba Lycopi, 14 parts of rhizoma pinellinae praeparata, 9 parts of Radix Codonopsis, 14 parts of wrinkled giant hyssop, 18 parts of Snakegourd Fruit, 14 parts of peach kernel, 18 parts of safflower, 14 parts of corydalis tuber, 18 parts of rhizoma cyperi, 14 parts of Ligusticum wallichii, excrementum pteropi 8 parts.
The present embodiment provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it is put into after well mixed in marmite, into marmite 1500ml water is added, is soaked 60 minutes;
2) after boiling by intense fire, being heated 30 minutes with slow fire, after temperature slightly drops, take filtrate, the dregs of a decoction in marmite are standby, and Filtrate is poured into container, obtains first time decoction;
3) hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then slow fire heating About 30 minutes, after temperature is down to room temperature, filtrate is taken, obtains second of decoction;
4) it well-done decoction will be put into same container, and be well mixed twice, it is filling close after obtained decoction is sterilized Envelope, obtains Traditional Chinese medicine composition liquid medicine.
The above method prepare be for traditional Chinese herbal decoction, the instructions of taking of this traditional Chinese herbal decoction:Take in three times within 1 day, it is big every time About 200ml.Also can 1 property decoct the dose of 2 days, filling and sealing after obtained decoction is sterilized, refrigeration, it is first pico- when taking plus Heat.
Embodiment six:
A kind of Chinese medicine composition for treating fatty liver, the Chinese medicine material matched by following parts by weight form:15 parts of radix bupleuri, 20 parts of stir-baked FRUCTUS TOOSENDAN, 30 parts of charred FRUCTUS CRATAEGI, 20 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 30 parts of the membrane of a chicken's gizzard, 25 parts of cassia seed, 15 parts of Herba Lycopi, 15 parts of rhizoma pinellinae praeparata, 10 parts of Radix Codonopsis, 15 parts of wrinkled giant hyssop, 20 parts of Snakegourd Fruit, 15 parts of peach kernel, 20 parts of safflower, 15 parts of corydalis tuber, 20 parts of rhizoma cyperi, 15 parts of Ligusticum wallichii, five spirits 9 parts of fat.
The present embodiment also provides a kind of preparation method for the Chinese medicine composition for treating fatty liver simultaneously, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it will be well mixed after the medicinal material drying of acquirement;
2) medicinal material after being well mixed in step 1) is ground into medicinal powder;
3) medicinal powder of step 2) is crossed into 600 mesh sieves and traditional Chinese medicine powder is made;
4) traditional Chinese medicine powder for obtaining step 3) is put sterilizes 1 hour under ultraviolet light, obtains Chinese medicine composition medicinal powder;
5):Chinese medicine composition medicinal powder made from step 4) is fitted into capsulae vacuus capsule is made, obtain Chinese medicine composition glue Capsule.
Chinese medicinal composition capsules prepared by the above method, instructions of taking are:Take at twice within 1 day, 10 grams every time (2).
The Chinese medicine composition for the treatment of fatty liver provided by the invention, so that with inducing diaphoresis, soothing the liver, the radix bupleuri of rising Yang is monarch drug in a prescription; With except damp and hot, clearing away the liver-fire, analgesic, the stir-baked FRUCTUS TOOSENDAN of desinsection, the stir-baked FRUCTUS CRATAEGI taste ministerial drug of promoting digestion and removing indigestion;With Jiao god of temperature food and stomach Bent, stomach strengthening and digestion promoting, the membrane of a chicken's gizzard of arresting seminal emission, heat-clearing improving eyesight, the cassia seed to relax bowel, promoting blood circulation and removing blood stasis, the pool of line water detumescence Blue, eliminating dampness and eliminating phlegm rhizoma pinellinae praeparata, tonifying middle-Jiao and Qi, the Radix Codonopsis of strengthening spleen and tonifying lung, fast gas, and in, ward off dirty, the wrinkled giant hyssop of clearing damp, heat-clearing are washed Phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, Snakegourd Fruit, the promoting blood circulation of ease constipation, relax bowel, relieving cough and asthma peach kernel, invigorate blood circulation, blood stasis removing analgesic it is red Flower, regulating qi-flowing for relieving pain, the corydalis tuber of promoting blood circulation to remove blood stasis, promoting qi circulation and removing obstruction in the collateral, the rhizoma cyperi of menstruction regulating and pain relieving, blood-activating and qi-promoting, the Ligusticum wallichii of wind-expelling pain-stopping are Adjutant;With removing blood stasis and hemostasis;The excrementum pteropi of disperse accumulations removing toxic substances is to make medicine.The Chinese medicine composition for the treatment of fatty liver provided by the invention, matches somebody with somebody 5 rationally, have no toxic side effect, can fundamentally treat fatty liver, efficacy stability is uneasy to recur, cheap.
The present invention has carried out clinical efficacy tracking with the data given by embodiment 3 simultaneously, and curative effect is summarized as follows:
1. selecting Patients with Fatty Liver 80, age 25-55 year, average age 41 years old, patient is randomly divided into two groups, treatment group 40, control group 20, there was no significant difference for the data such as two groups of ages, has comparativity.
2. treatment method, the oral Chinese medicine composition made from optimization formula embodiment 3 of the present invention for the treatment of group, per bu sooner or later Take twice, the course for the treatment of 30 days.The oral general health medicine of control group, according to dosage takes, the course for the treatment of 30 days with number daily.
3. diagnostic criteria, by medical history and auxiliary examination, Diagnosis of fatty of being not difficult.Can by liver function, blood fat, B ultrasound, face The order of severity of the comprehensive descision fatty livers such as bed symptom, if suspecting that disease development to the hepatic sclerosis stage, should also detect " liver fibre four The projects such as item ".
3.1. the diagnosis of NASH
(1) without history of drinking history or equivalent amount of alcohol male 140 grams of < weekly of drinking, 70 grams of women <.
(2) fatty liver can be caused by excluding virus hepatitis, DILD, total parenteral nutrition, hepatolenticular degeneration etc. Specified disease.
(3) in addition to primary disease clinical manifestation, there is the non-specific disease such as weak, indigestion, dull pain in liver, hepatosplenomegaly Shape and sign.
(4) overweight/Abdominal obesity, fasting blood-glucose can increase, the metabolic syndrome such as blood fat disorder, hypertension.
(5) serum transaminase and glutamyl transpeptidase level can be increased by mild to moderate, generally with phenylalanine ammonia group-transfer Based on enzyme rise.
(6) liver imageology performance meets the imaging diagnosis standard of diffusivity fatty liver.
(7) Hepatic biopsy changes the pathological diagnosis standard for meeting fatty liver disease.
All possess any one person in above-mentioned 1st~5 and the 6th or the 7th and can be diagnosed as fatty liver.
3.2. the diagnosis of alcoholic fatty liver
Long-term heavy drinking is the necessary requirement for diagnosing alcoholic fatty liver.General history of drinking history converted into amount of alcohol more than 5 years Male >=40g/d, there is heavy drinking history in women >=20g/d, or 2 weeks, convert into amount of alcohol > 80g/d.With reference to the clinic of patient Symptom, laboratory examination results, liver B ultrasound or CT examination have typical performance, can make diagnosis.
4. efficacy determination
Cure:Primary symptom full recovery, body are good without any discomfort, the state of mind;
It is effective:Primary symptom is largely recovered, and health is good, and the state of mind is good;
Effectively:Primary symptom is recovered normal or mitigated, and health gradually takes a turn for the better, and the state of mind is normal;
It is invalid:Symptom after taking medicine sign and the state of mind without improvement or improve unobvious.
5. treatment results, the cure rate for the treatment of group is 66%, effective 12%, effective 10%, invalid 12%, total effective rate 88%;The cure rate of control group is 15%, effective 10%, effective 5%, invalid 20%, total effective rate 40%.
As a result show, the Chinese medicine preparation for the treatment of fatty liver of the invention, drug effect well and stably, can be treated fundamentally Fatty liver, cheap, clinic popularization and application.
The Chinese medicine of the present invention has carried out toxicity test, and test effect is as follows:
From 18-22 grams of body weight, the healthy mice of 9 week old (homogeneous test body heavy phase difference is no more than 2 grams).Rat 12 weeks Age;120-150 grams of body weight, homogeneous test body heavy phase difference are no more than 10g.During experiment, animal is randomly divided into 4~5 groups by volume, Every group of at least 10 animals, to reaction of animals situation is observed after tested material at once, observation daily once, Continuous Observation 6 months, is seen Examine toxic reaction, should, pays attention to the record outward appearance of animal, behavioral activity, the state of mind, appetite (feed consumption), stool and urine and Its color, hair, the colour of skin, breathing, nose, eye, oral cavity secretion without exception, changes of weight etc., compared with control group, administration group is small White mouse health is normal, and has no that small white mouse is sick or dead.Prompt the medicine security good, have no toxic side effect.
The treatment case of the Chinese medicine composition of the present invention is as follows:
Case one, Zhang, man, 32 years old, often treated with courtesy due to work relationship and have a meal, drink, lack exercise again, worked 5 years Original 130 jin of body weight increase to 180 jin, and physical examination finds that fatty liver index is exceeded, and usually body is felt without obvious symptom Western medicine excitant is thought greatly very much to use Chinese medicine and dietetic regulation, comes here then and sought medical advice, and takes in the offer of the embodiment of the present invention 3 Medicine decoction is after 1 month, and Zai Qu hospitals, which check UP, finds that fatty liver index has been completely recovered to positive ordinary index, and the later stage adds diet Conditioning, it is all no abnormal during physical examination in two years.
Case two, Liu, male, 47 years old, cadre's (labor intensity is low), because " liver pain June " is medical.Patient mental, Appetite can.Deny hepatopathy family history, mother is diabetic.Patient drinks 25 years, B ultrasound of having a medical check-up prompting fatty liver 5 years.Look into Body:Blood pressure 150/90mmHg, body weight 75kg, height 170cm.The traditional Chinese medical science is had a medical check-up:Dark tongue quality, corpulent tongue, there is indentation, tongue is greasy in vain, arteries and veins String slide, take the embodiment of the present invention four offer Chinese medicinal capsule nurse one's health 3 months after, fatty liver index substantially returns to normally refer to Number, the later stage is by dietetic regulation and adheres to taking the present invention, and after half a year, body mass index makes moderate progress, then the symptom of without pain.
Case three, Mr. Wang, women, 58 years old, diet heavy wool was salty, likes eating meat, especially fat meat, usually likes Sweet food is eaten, blood glucose is higher, in the dizzy weak symptom of certain appearance, goes examination in hospital to learn with fatty liver.Take the present invention After the traditional Chinese herbal decoction two weeks that embodiment one provides, dizzy weak symptom disappears substantially, continues to take traditional Chinese herbal decoction two weeks, and Coordinate diet control and strengthen take exercise and then it is secondary remove examination in hospital, fatty liver index has been restored to regime values, spiritual shape State has also been got well much than before.Visited after half a year, no recurrence.
Case four, Lee, female, 28 years old, usually operating pressure was big, and diet is irregular, and ate and drank immoderately, and did not got enough athletic exercise.Essence Refreshing state is poor, and pale no color, belly is regular pain occurs, is learnt in the physical examination of a company organization with fat Fat liver, for deep conditioning body, fatty liver is treated, take the traditional Chinese herbal decoction of the offer of the embodiment of the present invention three one month, coordinated Regular diet and exercise, colic symptoms disappear, and the state of mind also recovers normal, and especially face has been got well much than in the past, goes to cure Institute's detection fatty liver index substantially returns to regime values, is after treatment, continues to take above-mentioned traditional Chinese herbal decoction one month, fat Liver index returns to regime values.Visited after half a year, no recurrence.
The foregoing description of the disclosed embodiments, those skilled in the art are enable to realize or using the present invention.To this A variety of modifications of a little embodiments will be apparent for a person skilled in the art, and generic principles defined herein can Without departing from the spirit or scope of the present invention, to realize in other embodiments.Therefore, the present invention will not be limited The embodiments shown herein is formed on, and is to fit to consistent with principles disclosed herein and features of novelty most wide Scope.

Claims (8)

1. a kind of Chinese medicine composition for treating fatty liver, it is characterised in that the Chinese medicine material matched by following parts by weight forms: Radix bupleuri 10-15 parts, stir-baked FRUCTUS TOOSENDAN 10-20 parts, charred FRUCTUS CRATAEGI 20-30 parts, stir-baked MASSA FERMENTATA MEDICI-NALIS 10-20 parts, the membrane of a chicken's gizzard 10-30 parts, cassia seed 15-25 parts, Herba Lycopi's 10-15 parts, rhizoma pinellinae praeparata 10-15 parts, Radix Codonopsis 6-10 parts, wrinkled giant hyssop 10-15 parts, Snakegourd Fruit 10-20 parts, peach kernel 10- 15 parts, safflower 10-20 parts, corydalis tuber 10-15 parts, rhizoma cyperi 10-20 parts, Ligusticum wallichii 10-15 parts, excrementum pteropi 6-9 parts.
2. the Chinese medicine composition for the treatment of fatty liver according to claim 1, it is characterised in that matched by following parts by weight Chinese medicine material composition:Radix bupleuri 12-14 parts, stir-baked FRUCTUS TOOSENDAN 12-18 parts, charred FRUCTUS CRATAEGI 22-28 parts, stir-baked MASSA FERMENTATA MEDICI-NALIS 12-18 parts, the membrane of a chicken's gizzard 12-28 parts, cassia seed 17-23 parts, Herba Lycopi's 12-14 parts, rhizoma pinellinae praeparata 12-14 parts, Radix Codonopsis 7-9 parts, wrinkled giant hyssop 12-14 parts, Snakegourd Fruit 12- 18 parts, peach kernel 12-14 parts, safflower 12-18 parts, corydalis tuber 12-14 parts, rhizoma cyperi 12-18 parts, Ligusticum wallichii 12-14 parts, excrementum pteropi 7-8 parts.
3. the Chinese medicine composition for the treatment of fatty liver according to claim 1, it is characterised in that matched by following parts by weight Chinese medicine material composition:11 parts of radix bupleuri, 11 parts of stir-baked FRUCTUS TOOSENDAN, 21 parts of charred FRUCTUS CRATAEGI, 11 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard 11, cassia seed 16 Part, 11 parts of Herba Lycopi, 11 parts of rhizoma pinellinae praeparata, 6 parts of Radix Codonopsis, 11 parts of wrinkled giant hyssop, 11 parts of Snakegourd Fruit, 11 parts of peach kernel, 11 parts of safflower, 11 parts of corydalis tuber, 11 parts of rhizoma cyperi, 11 parts of Ligusticum wallichii, 6 parts of excrementum pteropi.
4. the Chinese medicine composition for the treatment of fatty liver according to claim 1, it is characterised in that matched by following parts by weight Chinese medicine material composition:13 parts of radix bupleuri, 16 parts of stir-baked FRUCTUS TOOSENDAN, 26 parts of charred FRUCTUS CRATAEGI, 16 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, 26 parts of the membrane of a chicken's gizzard, cassia seed 22 parts, 13 parts of Herba Lycopi, 13 parts of rhizoma pinellinae praeparata, 8 parts of Radix Codonopsis, 13 parts of wrinkled giant hyssop, 16 parts of Snakegourd Fruit, 13 parts of peach kernel, 16 parts of safflower, corydalis tuber 13 Part, 17 parts of rhizoma cyperi, 13 parts of Ligusticum wallichii, 8 parts of excrementum pteropi.
5. a kind of preparation method of the Chinese medicine composition for the treatment of fatty liver as any one of claim 1-4, its feature It is, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, Wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it is put into marmite after well mixed, is added into marmite 1000-1500ml water, soak 30-60 minutes;
2) after boiling by intense fire, heated 30 minutes with slow fire, after temperature slightly drops, take filtrate, the dregs of a decoction in marmite are standby, and will filter Liquid is poured into container, obtains first time decoction;
3) hot water will be added in the dregs of a decoction in marmite in step 2), carries out secondary decoction, first boil by intense fire, then slow fire heating about 30 Minute, after temperature is down to room temperature, filtrate is taken, obtains second of decoction;
4) it well-done decoction will be put into same container, and be well mixed twice, filling and sealing after obtained decoction is sterilized, obtain To Traditional Chinese medicine composition liquid medicine.
6. a kind of preparation method of the Chinese medicine composition for the treatment of fatty liver as any one of claim 1-4, its feature It is, comprises the following steps:
1) weigh by weight radix bupleuri, stir-baked FRUCTUS TOOSENDAN, charred FRUCTUS CRATAEGI, stir-baked MASSA FERMENTATA MEDICI-NALIS, the membrane of a chicken's gizzard, cassia seed, Herba Lycopi, rhizoma pinellinae praeparata, Radix Codonopsis, Wrinkled giant hyssop, Snakegourd Fruit, peach kernel, safflower, corydalis tuber, rhizoma cyperi, Ligusticum wallichii and excrementum pteropi, it will be well mixed after the medicinal material drying of acquirement;
2) medicinal material after being well mixed in step 1) is ground into medicinal powder;
3) medicinal powder of step 2) is crossed into 500-800 mesh sieves and traditional Chinese medicine powder is made;
4) traditional Chinese medicine powder for obtaining step 3) is put sterilizes 1 hour under ultraviolet light, obtains Chinese medicine composition medicinal powder.
7. the preparation method of the Chinese medicine composition for the treatment of fatty liver according to claim 6, it is characterised in that including as follows Step:
Chinese medicine composition medicinal powder made from step 4) is fitted into capsulae vacuus capsule is made, obtain Chinese medicinal composition capsules.
8. the preparation method of the Chinese medicine composition for the treatment of fatty liver as claimed in claim 6, it is characterised in that in step 3) The granularity of the traditional Chinese medicine powder arrived is 600 mesh.
CN201711314716.9A 2017-12-12 2017-12-12 A kind of Chinese medicine composition for treating fatty liver and preparation method thereof Withdrawn CN107854588A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112370483A (en) * 2020-05-28 2021-02-19 仲崇允 Traditional Chinese medicine composition for treating fatty liver

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112370483A (en) * 2020-05-28 2021-02-19 仲崇允 Traditional Chinese medicine composition for treating fatty liver

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Application publication date: 20180330