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CN107823618A - A kind of Chinese medicine composition and its application - Google Patents

A kind of Chinese medicine composition and its application Download PDF

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Publication number
CN107823618A
CN107823618A CN201711339456.0A CN201711339456A CN107823618A CN 107823618 A CN107823618 A CN 107823618A CN 201711339456 A CN201711339456 A CN 201711339456A CN 107823618 A CN107823618 A CN 107823618A
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China
Prior art keywords
parts
radix
chinese medicine
root
medicine composition
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CN201711339456.0A
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Chinese (zh)
Inventor
李经中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quxian Xinshi Gonghe Chinese Herbal Medicine Farmers' Professional Cooperative
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Quxian Xinshi Gonghe Chinese Herbal Medicine Farmers' Professional Cooperative
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Priority to CN201711339456.0A priority Critical patent/CN107823618A/en
Publication of CN107823618A publication Critical patent/CN107823618A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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    • A61K36/18Magnoliophyta (angiosperms)
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Abstract

The invention discloses a kind of Chinese medicine composition and its application, it is related to pharmaceutical technology field, Chinese medicine composition provided by the invention is by RADIX ANGELICAE SINEINSIS, the root of herbaceous peony, radix glycyrrhizae, the non-irrigated tuber of pinellia, Ligusticum wallichii, the red sage root, blood clam, the root of Dahurain angelica, Radix Ginseng Rubra, American Ginseng, cassia twig, Donga glue, rhizoma zingiberis, the root bark of tree peony, the tuber of dwarf lilyturf, evodia rutaecarpa, finger citron sliced, citron, the dried immature fruit of citron orange, the profound Hu of vinegar system, Fructus Aurantii, the seed of jog's tears, Rhizoma Sparganii, the coptis, gypsum, purple perilla, lotus leaf, motherwort, the fruit of glossy privet, cortex albiziae, lotus rice, Gorgon fruit, Chinese yam, the Radix Astragali, Eclipta prostrata, cuttle bone, the medicine of the taste Chinese medicine of radix jurineae 37 composition.The Chinese medicine composition of present invention offer pair has blood circulation promoting and enriching, clearing heat and detoxicating, anti-inflammatory analgetic, nourishing Yin and promoting production of body fluid tonifying Qi, tranquilization and nourishing, and the effect of stomach invigorating spleen to remove dampness, particularly with treatment chronic gastritis is various, the microbial stomach trouble of H. pylori, insomnia, dysmenorrhoea have good therapeutic effect.

Description

A kind of Chinese medicine composition and its application
Technical field
The present invention relates to pharmaceutical technology field, more particularly to a kind of Chinese medicine composition and its application.
Background technology
Stomach trouble, it is many general designations with stomach relevant disease.They have similar symptom, as upper abdomen gastral cavilty portion discomfort, pain, Glutted after meal, belch, acid reflux, or even Nausea and vomiting etc..Clinically common stomach trouble has acute gastritis, chronic gastritis, stomach to burst Ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric concretion, the innocent and malignant tumour of stomach, also stomach lining take off Hang down disease, acute gastric dilatation, pyloric stenosis etc..Although stomach trouble is unlikely to threat to life, the long-term ailing life tormented to people Large effect is caused with work.In the therapeutic process of stomach trouble, particularly chronic gastropathy often occurs Relapse rate, controlled Situation about recurring more afterwards is, it is necessary to prolonged administration of drugs.The medicine for the treatment of stomach trouble is numerous at present, including Chinese medicine and Western medicine, long-term clothes With the side effect of Western medicine, larger and accordance with tolerance is strong, and Chinese medicine is generally traditional herbal medicine and is made, it is poor to stomach treatment and the foster effect of temperature, Curative effect is slow.
The content of the invention
The first object of the present invention is to provide a kind of Chinese medicine composition, to solve Western medicine secondary work during stomach trouble is treated Strong with larger and accordance with tolerance, the treatment of traditional Chinese medicine and temperature support the problem of effect is poor, curative effect is slow.
The second object of the present invention is to be that a kind of Chinese medicine composition is preparing the application for the treatment of dysmenorrhoea medicine.
The third object of the present invention is to be that a kind of Chinese medicine composition is preparing the application of medicament for treating insomnia.
A kind of Chinese medicine composition, in terms of parts by weight, it is made up of following components:10~20 parts of RADIX ANGELICAE SINEINSIS, the root of herbaceous peony 35~45 Part, 5~15 parts of radix glycyrrhizae, non-irrigated 5~15 parts of the tuber of pinellia, 5~15 parts of Ligusticum wallichii, 33~43 parts of the red sage root, 1~10 part of blood clam, the root of Dahurain angelica 1~10 Part, 5~15 parts of Radix Ginseng Rubra, 5~15 parts of American Ginseng, 3~13 parts of cassia twig, 5~15 parts of Donga glue, 3~13 parts of rhizoma zingiberis, the root bark of tree peony 1~ 11 parts, 5~15 parts of the tuber of dwarf lilyturf, 1~10 part of evodia rutaecarpa, 5~15 parts of finger citron sliced, 5~15 parts of citron, 5~15 parts of the dried immature fruit of citron orange, the profound Hu of vinegar system 10~20 parts, 1~10 part of Fructus Aurantii, 45~55 parts of the seed of jog's tears, 1~10 part of Rhizoma Sparganii, 15~25 parts of the coptis, 25~35 parts of gypsum, purple perilla 45~55 parts, 45~55 parts of lotus leaf, 45~55 parts of motherwort, 10~20 parts of the fruit of glossy privet, 5~15 parts of cortex albiziae, lotus rice 5~15 Part, 5~15 parts of Gorgon fruit, 10~20 parts of Chinese yam, 10~20 parts of the Radix Astragali, 10~20 points of Eclipta prostrata, 10~20 parts of cuttle bone, radix jurineae 5~15 parts.
Chinese medicine composition provided by the invention, be by RADIX ANGELICAE SINEINSIS, the root of herbaceous peony, radix glycyrrhizae, the non-irrigated tuber of pinellia, Ligusticum wallichii, the red sage root, blood clam, The root of Dahurain angelica, Radix Ginseng Rubra, American Ginseng, cassia twig, Donga glue, rhizoma zingiberis, the root bark of tree peony, the tuber of dwarf lilyturf, evodia rutaecarpa, finger citron sliced, citron, the dried immature fruit of citron orange, vinegar system are profound Recklessly, Fructus Aurantii, seed of jog's tears part, Rhizoma Sparganii, the coptis, gypsum, purple perilla, lotus leaf, motherwort, the fruit of glossy privet, cortex albiziae, lotus rice, Gorgon fruit, Chinese yam, The Radix Astragali, Eclipta prostrata, cuttle bone, the medicine of the taste Chinese medicine of radix jurineae 37 composition, there is blood circulation promoting and enriching, clearing heat and detoxicating, anti-inflammatory analgetic, support Yin and promoting production of body liquid tonifying Qi, and the effect of stomach invigorating spleen to remove dampness, particularly with treating, chronic gastritis is various good therapeutic effect.
RADIX ANGELICAE SINEINSIS, replenishing and activating blood, relax bowel;The root of herbaceous peony, also known as the raw root of herbaceous peony, heat-clearing, rush down soft liver of enriching blood, hold back that cloudy to receive sweat cool Blood;Honeysuckle, scientific name honeysuckle, dispelling wind-heat, also kind removing summer-heat blood poison, solve hot heat toxin disease;Radix glycyrrhizae, for four limbs contraction, Carbuncle sore tumefacting virus, alleviate drug toxicity;The non-irrigated tuber of pinellia, eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI;Ligusticum wallichii, blood-activating and qi-promoting, wind-expelling pain-stopping;The red sage root, again Name galloping horse grass, activates blood circulation and disperses blood clots, relieves pain promoting the circulation of qi;Blood clam, dissolving phlegm stagnation resolvation, softening and resolving hard mass, relieving haperacidity analgesic;The root of Dahurain angelica, the dehumidifying that gets rid of illness, The functions such as apocenosis myogenic, promoting blood circulation and stopping pain;Radix Ginseng Rubra, i.e. red ginseng, to be taken off for physically weak, and cold weak pulse of limb is Qi dysfunction in blood control;Cassia twig, tool There are complement sun, promoting blood circulation, warming spleen and stomach;Donga glue, there is the effect of tonifying the blood and arrest bleeding, nourishing Yin and moistening dryness;Rhizoma zingiberis, for gastral cavity abdomen The symptoms such as crymodynia, vomiting and diarrhea, cold weak pulse of limb;The root bark of tree peony, clearing heat and cooling blood are promoting blood circulation and removing blood stasis;The tuber of dwarf lilyturf, strong cloudy strengthening the essence, relieving restlessness of purging heat;Wu The fruit of medicinal cornel, vomited and diarrhoea for the cold syndrome in infant, abdominal distention, dysmenorrhea, Diarrhoea;Finger citron sliced, for indigestion, chest and abdomen the are swollen disease such as vexed Shape;Citron, treat for stomachache turgor, the modeling of phlegmatic cough's gas, the few food of the sound of vomiting of vomitting;Profound Hu, also known as corydalis tuber, corydalis tuber, promoting blood circulation, sharp gas, analgesic, The profound Hu of vinegar system, take net corydalis tuber to add vinegar to mix thoroughly, fried dry in braised through rearmounted pot, or take net corydalis tuber to add vinegar to boil altogether, boil to vinegar and exhaust, take out Dry, cut sheet or the used time smashs to pieces.Every 100 kilograms of corydalis tubers, 20 kilograms of vinegar, can also add suitable quantity of water to dilute;Fructus Aurantii, spleen benefiting and stimulating the appetite, The five internal organs are adjusted, lower gas, preventing or arresting vomiting is inverse, controls gastric disorder causing nausea, cholera rush down dysentery;The seed of jog's tears, invigorating spleen and reinforcing stomach, tonifying lung heat-clearing, expelling wind and eliminating dampness;The coptis, when controlling Row heat toxin, excess heat is vexed, and feeling of fullness is vomitted inverse, bacillary dysentery, and heat rushes down stomachache;Gypsum, expelling pathogenic factors from muscles for clearing heat, relieving restlessness are quenched the thirst, and control stomach fire headache;It is purple Soviet Union, and stomach sending down abnormally ascending, treat stomach Qi upward reversal;Lotus leaf, nature and flavor are bitter, put down, Return liver, spleen, stomach, the heart channel of Hang-Shaoyin;Motherwort, inducing diuresis for removing edema, clearly Thermal detoxification;The fruit of glossy privet, tonify the liver and kidney, improving eyesight, clearind deficient heat;Cortex albiziae, the five internal organs peace can be made and will is happy, to receive the Xie Yu that calms the nerves Effect;Lotus rice, also known as lotus seeds, very Energy benefit taste;Chinese yam, relax strengthening by means of tonics medicine, the wide intestines of invigorating spleen and reinforcing stomach, to gastrointestinal function decline Chronic diarrhea has the effect of preferable;Cuttle bone, can treat for stomachache noisy, belch pantothenic acid.
Preferably, the Chinese medicine composition, in terms of parts by weight, it is made up of following components:12~18 parts of RADIX ANGELICAE SINEINSIS, the root of herbaceous peony 37~43 parts, 7~13 parts of radix glycyrrhizae, non-irrigated 7~13 parts of the tuber of pinellia, 7~13 parts of Ligusticum wallichii, 35~41 parts of the red sage root, 3~8 parts of blood clam, the root of Dahurain angelica 3~8 parts, 7~13 parts of Radix Ginseng Rubra, 7~13 parts of American Ginseng, 5~11 parts of cassia twig, 7~13 parts of Donga glue, 5~11 parts of rhizoma zingiberis, the root bark of tree peony 3~9 parts, 7~13 parts of the tuber of dwarf lilyturf, 3~8 parts of evodia rutaecarpa, 7~13 parts of finger citron sliced, 7~13 parts of citron, 7~13 parts of the dried immature fruit of citron orange, vinegar system is profound 12~18 parts recklessly, 3~8 parts of Fructus Aurantii, 47~53 parts of the seed of jog's tears, 3~8 parts of Rhizoma Sparganii, 17~23 parts of the coptis, 27~33 parts of gypsum, purple perilla 47~53 parts, 47~53 parts of lotus leaf, 47~53 parts of motherwort, 12~18 parts of the fruit of glossy privet, 7~13 parts of cortex albiziae, lotus rice 7~13 Part, 7~13 parts of Gorgon fruit, 12~18 parts of Chinese yam, 12~18 parts of the Radix Astragali, 12~18 points of Eclipta prostrata, 12~18 parts of cuttle bone, radix jurineae 7~13 parts.
Further, the Chinese medicine composition, in terms of parts by weight, it is made up of following components:15 parts of RADIX ANGELICAE SINEINSIS, the root of herbaceous peony 40 Part, 10 parts of radix glycyrrhizae, non-irrigated 10 parts of the tuber of pinellia, 10 parts of Ligusticum wallichii, 38 parts of the red sage root, 5 parts of blood clam, 5 parts of the root of Dahurain angelica, 10 parts of Radix Ginseng Rubra, American Ginseng 10 parts, 8 parts of cassia twig, 10 parts of Donga glue, 8 parts of rhizoma zingiberis, 6 parts of the root bark of tree peony, 10 parts of the tuber of dwarf lilyturf, 5 parts of evodia rutaecarpa, 10 parts of finger citron sliced, citron 10 Part, 10 parts of the dried immature fruit of citron orange, profound 15 parts of Hu (vinegar system), 5 parts of Fructus Aurantii, 50 parts of the seed of jog's tears, 5 parts of Rhizoma Sparganii, 20 parts of the coptis, 30 parts of gypsum, purple perilla 50 Part, 50 parts of lotus leaf, 50 parts of motherwort, 15 parts of the fruit of glossy privet, 10 parts of cortex albiziae, 10 parts of lotus rice, 10 parts of Gorgon fruit, 15 parts of Chinese yam, the Radix Astragali 15 parts, Eclipta prostrata 15 is divided, 15 parts of cuttle bone, 10 parts of radix jurineae.
Further, Chinese medicine composition is active component, adds pharmaceutically acceptable auxiliary material or complementary composition system The standby preparation formed.
Further, preparation is pill, and the pill is water pill.Specifically, Chinese medicine composition is ground into fine powder, with Distilled water, ion exchange water or cold boiling water are that spherical dry pill is made in fine powder by excipient.Because its excipient is water solubility , take rear easy disintegrating and absorb, it is effective very fast.
Application of the above-mentioned Chinese medicine composition in the medicine for preparing treatment stomach trouble.
Further, the stomach trouble is chronic gastritis.Chronic gastritis mainly has five types, chronic antral gastritis:It is more normal See, site of pathological change is predominantly located at antrum portion;Acute gastritis:Rare, site of pathological change is predominantly located at body of stomach and stomach bottom, more by certainly Caused by body immune response;Chronic full gastritis:Lesion involves whole gastric mucosa, Ji Shaojian;It is broadly divided into by Histopathologic changes Two types, superficial gastritis:Lesion is confined to mucosal surface, and body of gland is intact;Atrophic gastritis:Inflammation by superficial by Gradually to caused by Deep Development, body of gland distortion, deformation, necrosis, or even atrophy.Be related in case chronic antral gastritis with it is rotten to the corn, Superficial gastritis, atrophic gastritis and the microbial stomach trouble of H. pylori, in addition chronic full gastritis and acute gastritis For seldom see with rare situation, therefore according to summarizing to obtain Chinese medicine composition provided by the invention on pathological tissue change type Chronic gastritis can effectively be treated.
Application of the above-mentioned Chinese medicine composition in the medicine for preparing treatment dysmenorrhoea.
Application of the above-mentioned Chinese medicine composition in the medicine for preparing treatment insomnia.
Compared with prior art, beneficial effects of the present invention are as follows:
(1) Chinese medicine composition prescription provided by the present invention is scientific and reasonable, and the bulk drug in prescription is not simply to be superimposed, Ingredients drug effect complements each other, and has positive synergy, not only rapid-action, its curative effect also significantly strengthens, Suo Youyuan Expect that medicinal material is conventional Chinese medicine, patient compliance is good, safe without toxic side effect;
(2) Chinese medicine preparation Small side effects provided by the invention, it is rapid-action, it is evident in efficacy, facilitate patient to use;
(3) preparation method of Chinese medicine composition provided by the present invention is simple and easy, and active constituent content is high, is adapted to big rule Mould produces.
Embodiment
In order to which those skilled in the art are better understood from the present invention, following examples are made to the present invention further detailed Description.
Embodiment 1
Chinese medicine composition, in terms of parts by weight, it is made up of following components:
10 parts of RADIX ANGELICAE SINEINSIS, 35 parts of the root of herbaceous peony, 5 parts of radix glycyrrhizae, non-irrigated 5 parts of the tuber of pinellia, 5 parts of Ligusticum wallichii, 33 parts of the red sage root, 1 part of blood clam, the root of Dahurain angelica 1 part, 5 parts of Radix Ginseng Rubra, 5 parts of American Ginseng, 3 parts of cassia twig, 5 parts of Donga glue, 3 parts of rhizoma zingiberis, 11 parts of the root bark of tree peony, 5 parts of the tuber of dwarf lilyturf, evodia rutaecarpa 10 Part, 5 parts of finger citron sliced, 5 parts of citron, 5 parts of the dried immature fruit of citron orange, 10 parts of the profound Hu of vinegar system, 1 part of Fructus Aurantii, 45 parts of the seed of jog's tears, 1 part of Rhizoma Sparganii, 15 parts of the coptis, 25 parts of gypsum, 45 parts of purple perilla, 45 parts of lotus leaf, 45 parts of motherwort, 10 parts of the fruit of glossy privet, 5 parts of cortex albiziae, 5 parts of lotus rice, 5 parts of Gorgon fruit, mountain 10 parts of medicine, 10 parts of the Radix Astragali, 10 parts points of Eclipta prostrata, 10 parts of cuttle bone, 5 parts of radix jurineae.
Water pill is prepared into according to common process.
Embodiment 2
Chinese medicine composition, in terms of parts by weight, it is made up of following components:
20 parts of RADIX ANGELICAE SINEINSIS, 45 parts of the root of herbaceous peony, 15 parts of radix glycyrrhizae, non-irrigated 15 parts of the tuber of pinellia, 15 parts of Ligusticum wallichii, 43 parts of the red sage root, 10 parts of blood clam, 10 parts of the root of Dahurain angelica, 15 parts of Radix Ginseng Rubra, 15 parts of American Ginseng, 13 parts of cassia twig, 15 parts of Donga glue, 13 parts of rhizoma zingiberis, 11 parts of the root bark of tree peony, the tuber of dwarf lilyturf 15 Part, 10 parts of evodia rutaecarpa, 15 parts of finger citron sliced, 15 parts of citron, 15 parts of the dried immature fruit of citron orange, 20 parts of the profound Hu of vinegar system, 10 parts of Fructus Aurantii, 55 parts of the seed of jog's tears, three 10 parts of rib, 25 parts of the coptis, 35 parts of gypsum, 55 parts of purple perilla, 55 parts of lotus leaf, 55 parts of motherwort, 20 parts of the fruit of glossy privet, 15 parts of cortex albiziae, 15 parts of lotus rice, 15 parts of Gorgon fruit, 20 parts of Chinese yam, 20 parts of the Radix Astragali, non-irrigated 20 parts of lotus, 20 parts of cuttle bone, 15 parts of radix jurineae.According to conventional work Skill is prepared into water pill.
Embodiment 3
Chinese medicine composition, in terms of parts by weight, it is made up of following components:
12 parts of RADIX ANGELICAE SINEINSIS, 37 parts of the root of herbaceous peony, 7 parts of radix glycyrrhizae, non-irrigated 7 parts of the tuber of pinellia, 7 parts of Ligusticum wallichii, 35 parts of the red sage root, 3 parts of blood clam, the root of Dahurain angelica 3 parts, 7 parts of Radix Ginseng Rubra, 7 parts of American Ginseng, 5 parts of cassia twig, 7 parts of Donga glue, 5 parts of rhizoma zingiberis, 3 parts of the root bark of tree peony, 7 parts of the tuber of dwarf lilyturf, 3 parts of evodia rutaecarpa, 7 parts of finger citron sliced, 7 parts of citron, 7 parts of the dried immature fruit of citron orange, 12 parts of the profound Hu of vinegar system, 3 parts of Fructus Aurantii, 47 parts of the seed of jog's tears, 3 parts of Rhizoma Sparganii, 17 parts of the coptis, gypsum 27 parts, 47 parts of purple perilla, 47 parts of lotus leaf, 47 parts of motherwort, 12 parts of the fruit of glossy privet, 7 parts of cortex albiziae, 7 parts of lotus rice, 7 parts of Gorgon fruit, Chinese yam 12 Part, 12 parts of the Radix Astragali, 12 parts of Eclipta prostrata, 12 parts of cuttle bone, 7 parts of radix jurineae.Water pill is prepared into according to common process.
Embodiment 4
Chinese medicine composition, in terms of parts by weight, it is made up of following components:
18 parts of RADIX ANGELICAE SINEINSIS, 43 parts of the root of herbaceous peony, 13 parts of radix glycyrrhizae, non-irrigated 13 parts of the tuber of pinellia, 13 parts of Ligusticum wallichii, 41 parts of the red sage root, 8 parts of blood clam, 8 parts of the root of Dahurain angelica, 13 parts of Radix Ginseng Rubra, 13 parts of American Ginseng, 11 parts of cassia twig, 13 parts of Donga glue, 11 parts of rhizoma zingiberis, 9 parts of the root bark of tree peony, 13 parts of the tuber of dwarf lilyturf, 8 parts of evodia rutaecarpa, 13 parts of finger citron sliced, 13 parts of citron, 13 parts of the dried immature fruit of citron orange, 18 parts of the profound Hu of vinegar system, 8 parts of Fructus Aurantii, 53 parts of the seed of jog's tears, 8 parts of Rhizoma Sparganii, 23 parts of the coptis, 33 parts of gypsum, 53 parts of purple perilla, 53 parts of lotus leaf, 53 parts of motherwort, 18 parts of the fruit of glossy privet, 13 parts of cortex albiziae, lotus rice 13 Part, 13 parts of Gorgon fruit, 18 parts of Chinese yam, 18 parts of the Radix Astragali, 18 parts of Eclipta prostrata, 18 parts of cuttle bone, 13 parts of radix jurineae.According to common process system It is standby into water pill.
Embodiment 5
Chinese medicine composition, in terms of parts by weight, it is made up of following components:
15 parts of RADIX ANGELICAE SINEINSIS, 40 parts of the root of herbaceous peony, 10 parts of radix glycyrrhizae, non-irrigated 10 parts of the tuber of pinellia, 10 parts of Ligusticum wallichii, 38 parts of the red sage root, 5 parts of blood clam, 5 parts of the root of Dahurain angelica, 10 parts of Radix Ginseng Rubra, 10 parts of American Ginseng, 8 parts of cassia twig, 10 parts of Donga glue, 8 parts of rhizoma zingiberis, 6 parts of the root bark of tree peony, 10 parts of the tuber of dwarf lilyturf, Wu 5 parts of the fruit of medicinal cornel, 10 parts of finger citron sliced, 10 parts of citron, 10 parts of the dried immature fruit of citron orange, profound 15 parts of Hu (vinegar system), 5 parts of Fructus Aurantii, 50 parts of the seed of jog's tears, 5 parts of Rhizoma Sparganii, 20 parts of the coptis, 30 parts of gypsum, 50 parts of purple perilla, 50 parts of lotus leaf, 50 parts of motherwort, 15 parts of the fruit of glossy privet, 10 parts of cortex albiziae, lotus rice 10 Part, 10 parts of Gorgon fruit, 15 parts of Chinese yam, 15 parts of the Radix Astragali, 15 parts of Eclipta prostrata, 15 parts of cuttle bone, 10 parts of radix jurineae.According to common process system It is standby into water pill.
It is a kind of clinical therapeutic efficacy of the Chinese medicine composition provided by the invention in chronic gastritis is treated below:
Patient:Choose 6~75 years old, the course of disease from 1 year to 10 years, by the undesirable trouble of multiple applications therapeutic effect
Person 200, wherein male 97, women 103.
Instructions of taking:Pill made of the Chinese medicine composition of the present invention of embodiment 5 is taken, early empty stomach is oral once daily,
Each 5g, the course for the treatment of are 22~28 days.
Curative effect judging standard:
Recovery from illness:Conditions of patients mitigates, and serious symptoms totally disappeared, and be kept for more than half a year no longer recur, and have no side effect;
It is effective:Conditions of patients mitigates, and serious symptoms totally disappeared, after being kept for half a year, symptom recurrence, but have no side effect;
Effectively:Patient symptom mitigates, but is not wholly absent;
It is invalid:Patient takes 3 courses for the treatment of, and state of an illness symptom does not mitigate.
Following table is clinical effectiveness table 1 of the Chinese medicine composition provided by the invention in treatment chronic gastritis:
As it can be seen from table 1 by different crowd, different sick times, the different stomach trouble state of an illness, clinical treatment experiment is done, Wherein use pill made of Chinese medicine composition provided by the invention, it is recovery from illness, effective and efficient reach 98%.
It is a kind of model case of the Chinese medicine composition provided by the invention in chronic gastritis is treated below:
Case 1
Chen, female, Han nationality, 25 years old, teacher.Live Qu County TianXing town, on March 13rd, 2011.Gastrocopy conclusion:Slowly Property superficial gastritis, HP:(+++) (helicobacter pylori is positive).Priority Jingqu county people's hospital, Chuanbei Medical College, southwest Hospital, affiliated hospital of Huaxi Medical Univ are diagnosed as chronic superficial gastritis.Cure 3 years and be not cured.Prolong in March, 2011 examine in I, it is glutted that quarter examines upper abdomen, aggravates after feed, when pain, poor appetite, nausea, belch, depressed, weak, vexed mistake Sleep.And long-term dysmenorrhoea.Body weight 40Kg, height 1.63Cm.Red tongue body tongue is thin, deep thready pulse string.Diagnosis is chronic gastritis.Give Square water pill is daily to be early administered at empty stomach 5g, once a day, even served June, all diseases, which are known, removes.5 years no relapse of follow-up.
Case 2
Mr. Li, Han nationality, man, 59 years old, live nine groups of Ford's stone column village.Suffer from acute gastritis, iterative method hair at the beginning of 2008 Disease, treat repeatedly, in July, 2014 aggravation, through People's Hospital, Sichuan Prov.'s gastrocopy and through organizing biopsy to be withered to be chronic Contracting gastritis, do not improved March through treating, changed the place of examination in January, 2015 in inventor, show as loss of appetite, become thin weak, Gas, nausea, vomiting, when feel under qi and have a pimple, white thick greasy, the deep-slow pulse of red tongue body tongue.Water pill 5g early is administered at empty stomach daily in it, even Take September recovery from illness, 1 year no relapse of follow-up.
Case 3
Section so-and-so, female, 73 years old, Han nationality, live Yingshan County kwan-yin town, go to a doctor in inventor on May 23rd, 2015, clinical table Existing stomach cusalgia, abdominal distention after meal, belch pantothenic acid, nausea and vomiting, bitter taste dry, vexed insomnia, the red tongue of tongue is how thick greasy, and arteries and veins is thin.Stomach Spectroscopy conclusion chronic antral gastritis is with rotten to the corn, esophageal reflux.Water pill 5g early is administered at empty stomach daily in it, even served rehabilitation recovery from illness in October. 3 years no relapse of follow-up.
Chronic gastritis mainly has five types, chronic antral gastritis:Relatively conventional, site of pathological change is predominantly located at antrum portion;Slowly Property body of stomach it is scorching:Rare, site of pathological change is predominantly located at body of stomach and stomach bottom, more caused by autoimmune response;Chronic full gastritis:Disease Whole gastric mucosa, Ji Shaojian are involved in change;Two types, superficial gastritis are broadly divided into by Histopathologic changes:Lesion is limited to It is intact in mucosal surface, body of gland;Atrophic gastritis:It is inflammation from superficial gradually to caused by Deep Development, body of gland distortion, becomes Shape, necrosis, or even atrophy.It is related to chronic antral gastritis in case with erosion, superficial gastritis, atrophic gastritis and pylorus Stomach trouble caused by pylori, but chronic full gastritis and acute gastritis is seldom are shown in and rare situation, therefore basis Summarize on pathological tissue change type Chinese medicine composition provided by the invention can effectively treat chronic gastritis and deep and remote rotation spiral shell The microbial stomach trouble of door rod;In addition, summarized by described above, pharmaceutical composition provided by the invention is controlled available for preparation Treat stomach trouble medicine.
It is a kind of clinical data of the Chinese medicine composition provided by the invention in treatment is had a sleepless night below:
As the medicine for the treatment of insomnia, 136 clinical observations of insomniac made a definite diagnosis are selected, patient is randomly divided into treatment group With two groups of control group, wherein treatment group 68, male 36, women 32,20~74 years old age, average age 43 years old, the course of disease 1 ~15 years;Control group 68, wherein male 35, women 33,23~70 years old age, average age 46 years old, the course of disease 1~16 Year;
The course of disease, the degrees of symptoms of two groups of cases for the treatment of group and control group are basically identical, no significant difference, have comparable Property.
Medicine of the present invention is taken by treatment group, and morning, empty stomach warm water was oral, one time a day, each 5g;23 days are 1 course for the treatment of, clothes With 2~3 courses for the treatment of.
Control group takes oryzanol tabletses, orally, one time 1~3,3 times a day, serious patient increases the amount of discretion.
Curative effect judging standard:
Cure:The symptoms such as sleep insufficiency, malaise, burnout sensation all disappear, and sleep recovers normally.
It is effective:Above-mentioned symptom substantially eliminates, basic improve of sleeping.
Effectively:Above-mentioned symptom disappears substantially, and sleep makes moderate progress.
It is invalid:Symptom is unchanged before the treatment.
Following table is clinical effectiveness table 2 of the Chinese medicine composition provided by the invention in treatment of insomnia patients shape:
Number of cases Cure It is effective Effectively It is invalid
Treatment group 68 39 15 11 3
Control group 68 24 17 9 18
It can be obtained by the data of table 2, the cure rate for the treatment of group and control group is respectively 57.4%, 35.3%;Treatment group and control The total effective rate of group is respectively 95.6%, 73.5%.According to data above can obtain treatment group cure rate and total effective rate it is high In treatment group, it can thus be concluded that Chinese medicine composition provided by the invention can be used for treatment of insomnia patients shape and have the effect of preferable.
It is a kind of clinical data of the Chinese medicine composition provided by the invention in dysmenorrhoea is treated below:
Case selection:Select in 196 clinical observations of inventor clinic dysmenorrhoea patient.By patient be randomly divided into treatment group and Control group, treatment group 98,13~32 years old age, average age 23 years old, the course of disease are average 4.5 years;Control group 98, the age 14~ 31 years old, average age 21 years old, the course of disease averagely 4.3 years.The course of disease, the degrees of symptoms of two groups of cases for the treatment of group and control group are basic Unanimously, no significant difference, there is comparativity.
Medicament selection:Medicine of the present invention is taken by treatment group, and daily empty stomach in morning is oral once, each 5g;It can continue after Take, daily empty stomach in morning is oral once, each 5g.
Control group YUEYUESHU TONGJIBAO KELI (Chinese medicines quasi-word Z41021972), packed 10g, 2 times a day, 1 wrap every time.
Two groups start to take for 7 days before menstrual period.
Efficacy determination:
Recovery from illness:Pain symptom substantially disappears, and constitution recovers normal, observes 1 year without recurrence;
It is effective:Pain symptom makes moderate progress, and constitution is progressively recovered;
Effectively:Pain relief, work can be adhered to by taking anodyne;
It is invalid:Pain symptom does not reach analgesic effect without change.
Following table is the clinical effectiveness table 3 of Chinese medicine composition provided by the invention:
Result is shown as can be seen from Table 3, thus the total effective rate for the treatment of group may be used apparently higher than the effective percentage of control group See that Chinese medicine composition provided by the invention can be used for the medicine for preparing treatment dysmenorrhoea, and there is preferable effect.
It is below the typical case in treatment dysmenorrhoea of Chinese medicine composition provided by the invention:
Case 1
Certain is gone into business, female, 29 years old.Distention and pain in the lower abdomen 8 years before and after menstrual period, very when vomit, it is black to measure few color, when press from both sides clot, god is tired weary Power, pink tongue, tongue is thin white, deep thready pulse.Throw top water pill and 5 grams are early administered at empty stomach daily, even served recovery from illness in March.Follow-up has no multiple for 5 years Hair.
Case 2
Lee, female, 32 years old.It is in a very depressed state, Breast bilges frowsty, all pain is swollen, dim black through measuring few color after before menstruation.It is general to throw top water Ball is early administered at empty stomach 5 grams daily, even served 2 months pain symptoms and disappears, has rosy cheeks, energetic, follow-up is not recurred for 2 years.
Case 3
Zhao, female, 28 years old, teacher.Pain is often in spastic, on lower abdomen pubis, with nausea,vomiting,diarrhea, The symptom such as dizzy, weak.Multi-treatment is invalid, and rear top water pill of throwing early is administered at empty stomach 5 grams daily, even served recovery from illness in March.Follow-up 3 Year no relapse.
Described above, only presently preferred embodiments of the present invention is not intended to limit the invention, patent protection model of the invention Enclose and be defined by claims, the equivalent structure change that every description with the present invention is made, all should similarly be included Within the scope of the present invention.

Claims (9)

1. a kind of Chinese medicine composition, it is characterised in that in terms of parts by weight, be made up of following components:10~20 parts of RADIX ANGELICAE SINEINSIS, in vain 35~45 parts of Chinese herbaceous peony, 5~15 parts of radix glycyrrhizae, non-irrigated 5~15 parts of the tuber of pinellia, 5~15 parts of Ligusticum wallichii, 33~43 parts of the red sage root, 1~10 part of blood clam, 1~10 part of the root of Dahurain angelica, 5~15 parts of Radix Ginseng Rubra, 5~15 parts of American Ginseng, 3~13 parts of cassia twig, 5~15 parts of Donga glue, rhizoma zingiberis 3~13 Part, 1~11 part of the root bark of tree peony, 5~15 parts of the tuber of dwarf lilyturf, 1~10 part of evodia rutaecarpa, 5~15 parts of finger citron sliced, 5~15 parts of citron, the dried immature fruit of citron orange 5~15 Part, profound 10~20 parts of Hu (vinegar system), 1~10 part of Fructus Aurantii, 45~55 parts of the seed of jog's tears, 1~10 part of Rhizoma Sparganii, 15~25 parts of the coptis, gypsum 25~35 parts, 45~55 parts of purple perilla, 45~55 parts of lotus leaf, 45~55 parts of motherwort, 10~20 parts of the fruit of glossy privet, cortex albiziae 5~15 Part, 5~15 parts of lotus rice, 5~15 parts of Gorgon fruit, 10~20 parts of Chinese yam, 10~20 parts of the Radix Astragali, 10~20 parts of Eclipta prostrata, cuttle bone 10 ~20 parts, 5~15 parts of radix jurineae.
2. Chinese medicine composition according to claim 1, it is characterised in that in terms of parts by weight, be made up of following components:Entirely 12~18 parts of Radix Angelicae Sinensis, 37~43 parts of the root of herbaceous peony, 7~13 parts of radix glycyrrhizae, non-irrigated 7~13 parts of the tuber of pinellia, 7~13 parts of Ligusticum wallichii, 35~41 parts of the red sage root, 3~8 parts of blood clam, 3~8 parts of the root of Dahurain angelica, 7~13 parts of Radix Ginseng Rubra, 7~13 parts of American Ginseng, 5~11 parts of cassia twig, Donga glue 7~13 Part, 5~11 parts of rhizoma zingiberis, 3~9 parts of the root bark of tree peony, 7~13 parts of the tuber of dwarf lilyturf, 3~8 parts of evodia rutaecarpa, 7~13 parts of finger citron sliced, 7~13 parts of citron, 7~13 parts of the dried immature fruit of citron orange, profound 12~18 parts of Hu (vinegar system), 3~8 parts of Fructus Aurantii, 47~53 parts of the seed of jog's tears, 3~8 parts of Rhizoma Sparganii, the coptis 17~23 Part, 27~33 parts of gypsum, 47~53 parts of purple perilla, 47~53 parts of lotus leaf, 47~53 parts of motherwort, 12~18 parts of the fruit of glossy privet, silk tree 7~13 parts of skin, 7~13 parts of lotus rice, 7~13 parts of Gorgon fruit, 12~18 parts of Chinese yam, 12~18 parts of the Radix Astragali, 12~18 parts of Eclipta prostrata, crow Crafty 12~18 parts of bone, 7~13 parts of radix jurineae.
3. Chinese medicine composition according to claim 1, it is characterised in that in terms of parts by weight, be made up of following components:Entirely 15 parts of Radix Angelicae Sinensis, 40 parts of the root of herbaceous peony, 10 parts of radix glycyrrhizae, non-irrigated 10 parts of the tuber of pinellia, 10 parts of Ligusticum wallichii, 38 parts of the red sage root, 5 parts of blood clam, 5 parts of the root of Dahurain angelica are red 10 parts of ginseng, 10 parts of American Ginseng, 8 parts of cassia twig, 10 parts of Donga glue, 8 parts of rhizoma zingiberis, 6 parts of the root bark of tree peony, 10 parts of the tuber of dwarf lilyturf, 5 parts of evodia rutaecarpa, Buddhist 10 parts of handsheet, 10 parts of citron, 10 parts of the dried immature fruit of citron orange, profound 15 parts of Hu (vinegar system), 5 parts of Fructus Aurantii, 50 parts of the seed of jog's tears, 5 parts of Rhizoma Sparganii, 20 parts of the coptis, 30 parts of gypsum, 50 parts of purple perilla, 50 parts of lotus leaf, 50 parts of motherwort, 15 parts of the fruit of glossy privet, 10 parts of cortex albiziae, 10 parts of lotus rice, Gorgon fruit 10 Part, 15 parts of Chinese yam, 15 parts of the Radix Astragali, 15 parts of Eclipta prostrata, 15 parts of cuttle bone, 10 parts of radix jurineae.
4. the Chinese medicine composition according to claims 1 to 3 any one is active component, add pharmaceutically acceptable auxiliary The preparation that material or complementary composition are prepared.
5. Chinese medicine composition according to claim 4, it is characterised in that the preparation is pill, and the pill is water General ball.
6. application of the Chinese medicine composition in the medicine for preparing treatment stomach trouble according to claims 1 to 3 any one.
7. application according to claim 5, it is characterised in that the stomach trouble is chronic gastritis.
8. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that it is preparing treatment emmenagogue Application in thing.
9. according to the Chinese medicine composition described in claims 1 to 3 any one, it is characterised in that it is preparing treatment insomnia medicine Application in thing.
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108721477A (en) * 2018-09-05 2018-11-02 陕西省万寿制药有限责任公司 A kind of pharmaceutical preparation and preparation method thereof for treating internal organs spasm
CN108721477B (en) * 2018-09-05 2021-03-23 陕西省万寿制药有限责任公司 Pharmaceutical preparation for treating organ spasm and preparation method thereof

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Application publication date: 20180323