CN107817218A - Full-automatic microscope continuous detecting system - Google Patents

Abstract

The invention discloses a fully automatic microscope continuous detection system, which includes a microscope detection device and a control system, and also includes a flat sheet transfer device, a scraper transfer device, a sampling and loading drive device and an auxiliary device. The flat sheet transfer device moves the clamping mechanism longitudinally to take out the flat glass slide from the clean sheet supply device, and after adding samples and scraping, it moves laterally to the area of the microscope inspection device and passes the microscope inspection device on the flat glass slide. samples were tested and recorded. The scraper transfer device and the sampling and loading driving device are fixed on the same combined frame and move horizontally synchronously. The auxiliary devices are sequentially arranged on one side of the combination frame. The invention realizes a series of coordinated and synchronous automatic operation functions from sampling, adding samples, scraping, smearing and transfer detection and reset. And the computer that performs image processing, detection and recognition on the imaging of the inspected object realizes the automatic detection and identification of the inspected object.

Description

Fully automated microscope continuous detection system

Technical field:

The invention belongs to the technical field of microscopic detection equipment for medical use, and in particular relates to a fully automatic microscope continuous detection system.

Background technique:

At present, microscopes have been widely used in various aspects such as medical treatment, scientific research and teaching, especially in the field of biomedicine. However, the operation and use of microscopes, as well as the storage, processing, and printing of image information are not very convenient at present, and most microscopes can only be operated manually. In recent years, although great progress has been made in the automation of microscopes, the degree of automation of microscopes is not very high.

The Chinese invention patent with the publication number CN1553241A discloses an automatic optical microscope, which includes a main microscope composed of eyepieces, objective lenses, a stage, a condenser, and an illumination source. Although an electric converter is provided, on the stage There are components such as a horizontal horizontal axis motor and a horizontal vertical axis motor, but it is mainly for improving the moving structure and control part of the top of the main microscope. The invention has the advantage of being able to realize automatic focusing and automatic scanning of images. Its disadvantage is that the degree of automation is not high, and the automatic movement of the specimen slide cannot be realized.

The Chinese invention patent with the publication number CN 105988209 A discloses a fully automatic detection system based on a microscope, including a mechanical system installed on a base, an optical microscope and a control system for a stepping motor for controlling the mechanical system, and also includes A CCD camera mounted on the optical microscope frame, and a computer located outside the base. The mechanical system moves the smear of the inspected object to the optical microscope. The light emitted by the light source of the optical microscope passes through the smear of the inspected object and is focused and imaged on the electronic eyepiece of the CCD camera through the objective lens. The CCD camera converts the optical signal of the image into The electrical signal is then sent to the computer for image processing and detection. This patent document is still aimed at the technical improvement of the microscope in CCD camera imaging. Although the degree of automation has been improved to a certain extent and the labor cost has been reduced, manual participation is still required in adding samples and smears, and automatic tilting cannot be realized. Slides and samples are coordinated and synchronized, so the purpose of fully automated detection cannot be achieved.

Invention content:

The present invention aims at the problem that existing microorganism culture or detection equipment has a single structure and cannot realize comprehensive automatic detection, and provides a fully automatic microscope continuous detection system.

Technical solution: A fully automatic microscope continuous detection system, which includes a microscope detection device and a control system arranged on the bottom plate, a sampling and loading device, a sample and nozzle box, and also includes a slanted slide supply device, a slanted slide transfer device, Flat slide supply unit and flat slide transfer unit.

The inclined slide transfer device and the sampling and loading device are fixed on the same combined frame and driven to move synchronously.

The inclined slide transfer device includes a drive mechanism 1 capable of vertically moving the lifting slider 1; an elastically opened jaw is installed on the lower end of the lifting slider 1, and the swingable mouthpiece of the jaw is equipped with a Sliding shaft one is provided with a guide sliding structure on one side of the combined frame to make the sliding shaft one move down to be close to the combined frame so as to close the jaws. Simultaneously, the lower end of the lifting slide block 1 is equipped with a pressing pulley through an extension rod.

The inclined slide supply device includes a shaft support and an oblique support fixed on the bottom plate, the upper end of the shaft support is hinged with an L-shaped swing rod through a rotating shaft, and one end of the L-shaped swing rod is connected to the lifting slider by a transmission. ; An inclined push plate capable of translating along the inclined support is installed on one side of the inclined support, and the inclined push plate is in transmission connection with the other end of the L-shaped swing bar; a stack of inclined glass sheets is fixed on the inclined support Put the box, the lower side of the inclined push plate is located at the bottom of the inclined slide stacking box. When the inclined push plate moves upwards, it can push the inclined slides at the bottom of the inclined slide stacking box upwards, so that the bottom inclined slides can be pushed into the box. The jaw position.

The transfer device for flat glass slides includes a longitudinal movement mechanism and a transverse movement mechanism based on the longitudinal movement mechanism. A support is fixed on the lower side of the front end of the transverse movement mechanism, and an elastically closed bayonet nozzle is installed on the support. , on the bottom plate located below the transfer device for flat slides, there is a piece-taking support pressing block, and a piece-discharging support pressing block is arranged at the waste piece recovery and position. After contact, the nozzle can be opened.

The flat glass slide supply device includes a flat glass slide stacking box fixed on the base, the lower end of the flat glass slide stacking box is open and provided with a push plate capable of translation back and forth, and the push plate is connected with a transmission mechanism to realize The forward and backward translation pushing process; a push groove is arranged on the upper side of the push plate, and the flat slide located in the flat slide stacking box can fall into the push groove, and the push groove pushes the flat slide to the Nozzle position.

The flat glass slide transfer device moves longitudinally, and the flat glass slide is taken out from the flat glass slide supply device by using the clamping mechanism (job nozzle), and after adding samples and scraping, it is moved laterally to the microscope In the detection device area, the microscope detection device detects and records the samples on the flat glass slide, and then returns to unload the flat glass slide and resets; the inclined slide transfer device and the sampling and loading device move synchronously, and both There is the following cooperative relationship between the slide supply device and the flat glass slide supply device, the waste slide recovery box and the sample and nozzle box: (1) The inclined slide transfer device and the sampling and loading device are located at the same time in the inclined slide supply device and the flat slide glass When the slide supply device is on the upper side, the inclined slide transfer device moves down to position B to take the inclined slide, and the sampling and loading device loads the sample on the flat glass slide; (2) The inclined slide transfer device and the sampling and loading device are simultaneously located When the slide supply device and the waste recovery box are above, the inclined slide transfer device will continue to move the inclined slide to position C and press against one end of the flat glass slide, and the flat glass slide will be moved by the flat slide transfer device After pulling in the longitudinal direction, the sample on the flat glass slide is scraped flat, at this time, the sampling and adding device retracts the suction nozzle after adding the sample; (3) The inclined slide transfer device and the sampling and adding device are located in the waste film recovery box and the waste film recovery box at the same time. When the sample and the nozzle box are above, the inclined slide transfer device moves up to position A to return the inclined slide, and the sampling and adding device inserts the nozzle and sucks the sample; the above (1)-(3) reciprocating cycle.

The flat glass slide transfer device includes two parallel longitudinal slides fixed on the base plate, vertical sliders are respectively installed on the two vertical slides, and horizontal slides are fixed on the two vertical slides. A longitudinal drive mechanism for block movement on the vertical slideway, a cross slide block is installed on the cross slideway, and a transverse drive mechanism is provided to make the cross slide block move on the cross slideway; the front end of the cross slide block is fixed There is a support on which an L-shaped nozzle is hinged through a pin shaft. The upper side of the L-shaped nozzle protrudes from the upper side of the horizontal slider, and a spring is provided to keep the nozzle and the horizontal slider tightly pressed. or torsion spring.

The device for transporting the inclined glass slides comprises a lifting motor for taking inclined slides fixed on the combination frame, a driving pulley 1 is installed on its rotating shaft, a shaft sleeve 1 is fixed on the combination frame, and a vertical rotating shaft 1 is installed in the shaft sleeve 1. The upper end of the vertical rotating shaft 1 is equipped with a driven pulley 1, and the driving pulley 1 and the driven pulley 1 are driven by a belt; the lower end of the vertical rotating shaft 1 is screwed with a lifting slider 1, and the The lower end of the vertical slider 1 is fixed with a diagonal brace, and the diagonal brace is hinged on the lower side of the diagonal brace through a pin shaft. The diagonal brace is kept away from the diagonal brace by the pressure of the spring or torsion spring; Slideways are fixed in parallel on the frame; sliding shafts one are symmetrically installed on both sides of the inclined pressure plate, and each sliding shaft one is matched and installed in the corresponding slideway; the slideway includes an upper section and a lower section with smooth transition, both sections Parallel to the combined frame, but the width d1 of the lower segment from the combined frame is smaller than the width d2 of the upper segment from the combined frame.

The sampling and adding device includes a sampling lifting motor fixed on the combined frame, the driving pulley 2 is installed on the rotating shaft, the shaft sleeve 2 is fixed on the combined frame, the vertical rotating shaft 2 is installed in the shaft sleeve 2, and the vertical rotating shaft 2 The upper end of the upper end is equipped with a driven pulley two, and the driving pulley two and the driven pulley two are driven by a belt; the lower end of the vertical rotating shaft two is screwed with a lifting slider two, and the vertical slider two The lower end of the second is fixed with a sampling mechanism.

A flexible buffer layer is arranged in the pushing groove.

The present invention has the following beneficial effects: on the basis of the existing optical microscope imaging technology and automatic control system, the present invention adopts the combination of flat slide transfer device, oblique slide transfer device, sampling and loading device and other auxiliary devices, Realize a series of coordinated and synchronous automatic operation functions from sampling, adding samples, taking oblique slides, smears and transfer detection and reset. And the computer for image processing, detection and recognition of the object under inspection realizes the automatic detection and recognition of the object under inspection. The invention has a high degree of automation, greatly simplifies the detection procedure, reduces the problems caused by labor costs and operational errors, improves the detection speed and efficiency, and improves the medical detection environment.

Description of drawings

Fig. 1 is a schematic diagram of the appearance structure of the present invention.

FIG. 2 is one of the schematic diagrams of the internal structure of FIG. 1 .

FIG. 3 is a top view of FIG. 2 .

Fig. 4 is a schematic diagram of the movement relationship of the flat slide transfer device in Fig. 3 .

Fig. 5 is a schematic diagram of the kinematic relationship between the combination rack carrying the inclined slide transfer device and the sampling and loading device in Fig. 3 .

Fig. 6 is a schematic diagram of the operating mechanism of the inclined slide.

FIG. 7 is a schematic diagram of the side structure of FIG. 6 .

Fig. 8 is a schematic diagram of a transfer mechanism for flat slides.

FIG. 9 is a schematic top view of the structure of FIG. 8 .

FIG. 10 is a schematic diagram of the side structure of FIG. 8 .

Fig. 11 is the second schematic diagram of the internal structure of Fig. 1 .

Fig. 12 is a schematic diagram of a flat slide buffer structure.

Fig. 13 is a schematic diagram of the initial state of the cooperation between the inclined slide transfer device and the inclined slide supply device.

Fig. 14 is a schematic diagram of the termination state of the cooperation between the inclined slide transfer device and the inclined slide supply device.

Fig. 15 is a schematic diagram of the cooperative working state of the flat slide transfer device and the flat slide supply device.

FIG. 16 is a schematic perspective view of FIG. 15 .

The number 1 in the figure is the shell, 2 is the base plate, 3 is the flat glass slide transfer device, 301 is the horizontal slide, 302 is the right vertical slide, 303 is the right vertical slide, 304 is the left vertical slide, 305 is the left vertical slideway, 306 is the drive motor for traverse, 307 is the drive pulley for traverse, 308 is the driven pulley for traverse, 309 is the transverse belt, 310 is the drive motor for longitudinal movement, and 311 is the drive belt for longitudinal movement Wheel, 312 is a fixed plate 1, 313 is a longitudinally moving driven pulley, 314 is a horizontal slider, 315 is a bearing, 316 is a bayonet, 317 is a pin shaft, 318 is a flexible cushion block 1, and 319a is a sheet support Pressing block, 319b is the unloading support pressing block, 320 is the longitudinal belt, 321 is the second fixed plate, 4 is the driving device for the lateral movement of the combined frame, 401 is the fixed vertical plate and the horizontal slideway, 402 is the L-shaped combined frame, and 403 is the Drive motor, 404 is a driving pulley, 405 is a driven pulley, 406 is a belt, 5 is a sampling device, 501 is a sampling lifting motor, 502 is a driving pulley two, 503 is a driven pulley two, and 504 is a Belt, 505 is the shaft sleeve 2, 506 is the vertical shaft 2, 507 is the lifting slider 2, 508 is the fixed seat, 509 is the sampling mechanism, 510 is the suction nozzle, 6 is the inclined slide transfer device, 601 is the inclined glass Sheet lifting motor, 602 is a driving pulley one, 603 is a driven pulley one, 604 is a belt, 605 is a vertical shaft one, 606 is a slideway support, 607 is a slideway, 608 is a lifting slider one, and 609 is a slide Shaft 1, 610 is a slanting plate, 611 is a slanting brace, 612 is a shaft sleeve 1, 613 is a pin shaft, 614 is a flexible spacer 2, 615 is an extension rod, 616 is a pressing pulley, 7 is an inclined slide supply device , 701 is a shaft support, 702 is a rotating shaft, 703 is an L-shaped swing rod, 704 is a sliding slope, 705 is a guide hole, 706 is an oblique support, 707 is a sliding shaft 2, 708 is an oblique push plate, and 709 is an oblique glass 8 is a flat glass slide supply device, 801 is a flat glass slide stacking box, 802 is a push plate, 803 is a push groove, 804 is a buffer pad, 805 is a threaded slider, 806 is a screw, 807 is a motor; 9 is a sample and suction nozzle box, 10 is a waste sheet recovery box, 11 is a circuit board, 12 is a microscope detection device, 13 is a flat glass slide, and 14 is an oblique glass slide.

Detailed ways:

The appearance of the automatic microscope continuous detection system is shown in Figure 1, which includes a housing 1 and an operating window. Its internal structure is shown in Figure 2, and the main part is that a flat slide transfer device 3, a flat slide supply device 8, an oblique slide transfer device 6 and an oblique slide supply device are arranged on the bottom plate 2. As well as the sampling and loading device 5, the waste sheet recovery box 10, the sample and nozzle box 9, the microscope detection device 12, the circuit board 11 and the control system, etc.

It can be seen from Fig. 4 that the flat glass slide transfer device 3 moves longitudinally, and the flat glass slide 13 is taken out from the flat glass slide supply device 8 by using the clamping mechanism, and after adding samples and scraping, it moves laterally In the area of the microscope detection device 12, the samples on the flat glass slide 13 are detected and recorded by the microscope detection device 12, and then the flat glass slide 13 is removed and reset.

Referring to Fig. 9, Fig. 10 and Fig. 11 for the specific structure, it can be known that the flat slide transfer device 3 includes two parallel longitudinal slides fixed on the bottom plate 2, and the two ends of the slides are respectively installed on the first fixed plate and the second fixed plate , a longitudinal drive mechanism is provided to make the vertical slide block move on the vertical slideway. Specifically, a longitudinal driven pulley is installed on the fixed plate 1, a longitudinal drive motor is installed on the fixed plate 2, a longitudinal driving pulley is installed on its rotating shaft, and the longitudinal driving pulley and the longitudinal driven pulley are sleeved with Looped longitudinal belt.

Vertical sliders are respectively installed on the two longitudinal slideways, and the vertical sliders on both sides are respectively fixed with the corresponding longitudinal belts, so that the vertical sliders can be driven to move when the longitudinal belts rotate.

Simultaneously, a transverse slideway is fixed on the two vertical slide blocks, and a transverse driving mechanism is arranged to make the transverse slide block move on the transverse slideway. Specifically, a transverse driving motor and a transverse driven pulley are respectively installed on the two vertical sliders, a transverse driving pulley is installed on the rotating shaft of the transverse driving motor, and the transverse driving pulley and the transverse driven pulley are set There are endless transverse belts.

A transverse slide block is installed on the transverse slideway, and the transverse slide block is fixed with the transverse belt so that the transverse slide block can be driven to move when the transverse belt rotates.

It can be seen from Figure 11 that a support is fixed on the lower side of the front end of the horizontal slider, and an L-shaped mouth is hinged on the support through a pin shaft, and the upper side of the L-shaped mouth extends out of the horizontal slider. The upper side is provided with a spring or a torsion spring that keeps the jaw and the horizontal slide block tightly pressed. After the vertical slide block is pushed forward, the horizontal slideway and the horizontal slide block are driven to move forward together. When the L-shaped bayonet contacts the sheet-taking support pressing block 319a or the sheet-discharging support pressing block 319b, the L-shaped clamping mouth The mouth opens automatically, so that the flat glass slide 13 is taken or the flat glass slide 13 is unloaded. The structures and functions of the sheet-taking support pressing block 319a and the unloading support pressing block 319b are the same, but the lateral positions are different. After the horizontal slider moves laterally, it can choose to contact with the sheet taking support pressing block 319a or the sheet unloading supporting pressing block 319b to realize its function.

As can be seen from Figure 15 and Figure 16, the flat glass slide supply device includes a flat glass slide stacking box fixed on the base, the lower end of the flat glass slide stacking box is open and is provided with a push plate that can translate back and forth It is connected with the transmission mechanism to realize the forward and backward translation pushing process; a pushing groove is arranged on the upper side of the pushing plate, and the flat slides located in the flat slide stacking box can fall into the pushing groove. A nut slider is fixed at the bottom of the push plate, and a screw rod is installed in the threaded hole of the nut slider.

It can be seen from FIG. 5 and FIG. 6 that the inclined slide transfer device 6 and the sampling and loading device 5 are fixed on the same L-shaped combined frame 402 and traverse synchronously. The combination frame traversing driving device 4 that drives the L-shaped combination frame 402 to move laterally includes a set of fixed vertical plates and horizontal slides arranged on the bottom plate 2, and the driving motor is fixed on one end of the fixed vertical plate. The driving pulley is installed, and the other end of the fixed vertical plate is equipped with a driven pulley, the driving pulley and the driven pulley are surrounded by belts, and the L-shaped combination frame 402 is installed on the horizontal slideway and can slide, L Type combination frame 402 is fixed on the belt again. Therefore, when the driving motor drives the belt to rotate, it can drive the L-shaped combined frame 402 to perform lateral reciprocating motion.

It can be seen from Fig. 13 and Fig. 14 that the inclined slide supply device includes a shaft support and an oblique support fixed on the bottom plate, an L-shaped swing rod is hinged on the upper end of the shaft support through a rotating shaft, and one end of the L-shaped swing rod is provided with a sliding Inclined surface, the sliding inclined surface cooperates with the pressing pulley to slide, and the other end of the L-shaped swing rod is provided with a guide hole; on one side of the inclined support, an inclined push plate capable of translation along the inclined support is installed, and the inclined push One side of the plate is installed with two sliding shafts, which are matched and set in the guide hole; a stacking box for oblique slides is fixed on the oblique support, and the lower side of the oblique push plate is located on the oblique glass. the bottom of the sheet stacking box.

The sample and nozzle box 9 in the present invention, as well as the microscope detection device 12 and the control system are all realized by known technologies. The microscope detection device 12 includes processes such as staining, drying, photographing and microscopic detection of flat glass slides.

Referring to Fig. 5, the oblique slide transfer device 6, the sampling and loading device 5 and the auxiliary devices include the following cooperative relations: (1) the oblique slide transfer device 6 and the sampling and loading device 5 are located at the same time on the oblique slide supply device 7 and the flat glass slide When the slide supply device 8 is on the upper side, the inclined slide transfer device 6 moves down to position B to take the inclined slide, and the sampling and loading device 5 applies samples to the flat glass slide 13; (2) the inclined slide transfer device 6 and the sampling and loading device When the sample device 5 is located above the flat glass slide supply device 8 and the waste film recovery box 10 at the same time, the inclined slide transfer device 6 continues to move the inclined slide downward to position C, and then presses it against one end of the flat glass slide 13, and waits The flat glass slide transfer device 3 pulls the flat glass slide 13 longitudinally so that the sample on the flat glass slide 13 is scraped flat (smeared), and at this time, the sampling and loading device 5 will take the sample after the sample is added. (3) When the inclined slide transfer device 6 and the sampling and adding device 5 are located above the waste film recovery box 10 and the sample and nozzle box 9 at the same time, the inclined slide transfer device 6 moves upward to position A to remove the inclined slide. Glass slides, the sampling and loading device 5 inserts the suction nozzle and draws the sample. The above (1)-(3) reciprocating cycle. Where position A is higher than position B, and position B is higher than position C.

The specific structure of the sampling and adding device 5 is shown in Fig. 6, including a sampling lifting motor fixed on the combined frame, the driving pulley 2 is installed on its rotating shaft, the shaft sleeve 2 is fixed on the combined frame, and the vertical rotating shaft is installed in the shaft sleeve 2 Two, the upper end of the vertical rotating shaft 2 is equipped with a driven pulley 2, and the driving pulley 2 and the driven pulley 2 are driven by a belt; the lower end of the vertical rotating shaft 2 is threadedly connected with a lifting slider 2. The lower end of the vertical slide block 2 is fixed with a sampling mechanism. The sampling mechanism is a commonly used liquid sampling mechanism at present, and its structure and working principle are not described in detail. The process of moving and sucking the sample after the suction nozzle is installed at the lower end of the telescopic tube of the sampling mechanism is also a known technology and will not be described in detail.

See Fig. 7 and Fig. 8 for the inclined slide transfer device 6, which includes a lifting motor for taking oblique slides fixed on the combined rack, a driving pulley 1 is installed on its rotating shaft, a shaft sleeve 1 is fixed on the combined rack, and the shaft sleeve 1 is installed inside. There is a vertical rotating shaft 1, and a driven pulley 1 is installed on the upper end of the vertical rotating shaft 1, and the driving pulley 1 and the driven pulley 1 are driven by a belt; the lower end of the vertical rotating shaft 1 is screwed with a lifting slide Block 1, a slanting brace is fixed at the lower end of the vertical slider 1, and an oblique pressure plate is hinged on the lower side of the slant brace through a pin shaft, and the oblique pressure plate is kept in contact with the diagonal brace by the pressure of a spring or a torsion spring. Stay away from the trend; at the same time, slideways are fixed parallel on the combination frame; sliding shafts are installed symmetrically on both sides of the inclined plate, and each sliding shaft is matched and installed in the corresponding slideway; the slideway includes an upper section with a smooth transition and the lower section, both sections are parallel to the combined frame, but the width d1 of the lower section from the combined frame is less than the width d2 of the upper section from the combined frame. Therefore, when the sliding shaft moves downward, it is located at the lower section of the slideway, which is closer to the combined frame, and can force the inclined pressing plate to approach the inclined brace plate to realize the operation process of clamping the inclined glass slide. When the slide shaft moved upwards, it was located at the upper section of the slideway, far away from the combination frame, and could release the inclined pressing plate, so that the inclined pressing plate was far away from the inclined brace plate, so as to realize the operation process of releasing the inclined slides.

In order to achieve the purpose of buffering and not damaging the flat glass slide 13 , a flexible buffer layer or an elastic buffer mechanism can be provided on the support surface area below the flat glass slide 13 . And a flexible pad 1 is arranged inside the L-shaped mouthpiece. A flexible cushion block 2 is arranged on the inner side of the oblique pressure plate.

Claims (5)

1. A fully automatic microscope continuous detection system, including a microscope detection device and a control system arranged on the bottom plate, a sampling and adding device, a sample and a nozzle box, and is characterized in that: it also includes a sloped slide supply device, a sloped slide Transfer device, flat slide supply device and flat slide transfer device; The inclined slide transfer device and the sampling and loading device are fixed on the same combined frame and driven to move synchronously; The inclined slide transfer device includes a driving mechanism capable of vertically moving the lifting slider 1; an elastically opened jaw is installed on the lower end of the lifting slider 1, and a slide is installed on the swingable mouth piece of the jaw. Shaft 1 is provided with a guide sliding structure on the side of the combined frame that allows the sliding shaft 1 to move closer to the combined frame and then close the jaws after moving down; The inclined slide supply device includes a shaft support and an oblique support fixed on the bottom plate, the upper end of the shaft support is hinged with an L-shaped swing rod through a rotating shaft, and one end of the L-shaped swing rod is connected to the lifting slider by a transmission. ; An inclined push plate capable of translating along the inclined support is installed on one side of the inclined support, and the inclined push plate is in transmission connection with the other end of the L-shaped swing bar; a stack of inclined glass sheets is fixed on the inclined support Put the box, the lower side of the inclined push plate is located at the bottom of the inclined slide stacking box. When the inclined push plate moves upwards, it can push the inclined slides at the bottom of the inclined slide stacking box upwards, so that the bottom inclined slides can be pushed into the box. the jaw position; The transfer device for flat glass slides includes a longitudinal movement mechanism and a transverse movement mechanism based on the longitudinal movement mechanism. A support is fixed on the lower side of the front end of the transverse movement mechanism, and an elastically closed bayonet nozzle is installed on the support. , on the bottom plate located below the transfer device for flat slides, there is a piece-taking support pressing block, and a piece-discharging support pressing block is arranged at the waste piece recovery and position. The mouth can be opened after contact; The flat glass slide supply device includes a flat glass slide stacking box fixed on the base, the lower end of the flat glass slide stacking box is open and provided with a push plate capable of translation back and forth, and the push plate is connected with a transmission mechanism to realize The forward and backward translation pushing process; a push groove is arranged on the upper side of the push plate, and the flat slide located in the flat slide stacking box can fall into the push groove, and the push groove pushes the flat slide to the mouth position; The flat glass slide transfer device moves longitudinally, uses the nozzle to take out the flat glass slide from the flat glass slide supply device, and after adding samples and scraping, moves laterally to the area of the microscope detection device and passes through the microscope. The detection device detects and records the samples on the flat glass slide, and then returns to unload the flat glass slide and resets; the inclined slide transfer device and the sampling and loading device move synchronously, and both are connected with the inclined slide supply device and the loading device. There is the following cooperative relationship between the slide supply device, the waste slide recovery box and the sample and nozzle box: (1) The inclined slide transfer device and the sampling and loading device are located on the upper side of the inclined slide supply device and the flat slide supply device at the same time , the inclined slide transfer device moves down to position B to take the inclined slide, and the sampling and loading device loads samples on the flat glass slide; (2) The inclined slide transfer device and the sampling and loading device are located in the flat slide supply device and above the waste recovery box, the inclined glass slide transfer device will continue to move the inclined glass slide to position C and press it against one end of the flat glass slide, and the flat glass slide will be pulled by the flat glass slide transfer device in the longitudinal direction. The sample on the flat glass slide is scraped flat, at this time, the sampling and adding device retracts the suction nozzle after sampling; (3) The inclined slide transfer device and the sampling and sampling device are located in the waste recovery box and the sample and suction nozzle box at the same time When it is up, the slant slide transfer device moves up to position A to return the slant slide, and the sampling and loading device inserts the suction nozzle and sucks the sample; the above (1)-(3) reciprocating cycle. 2. The automatic microscope continuous detection system according to claim 1, characterized in that: said flat glass slide transfer device comprises two longitudinal slides fixed on the base plate in parallel, on which two vertical slides are installed respectively The vertical slider, the two vertical sliders are fixed with horizontal slides, and a longitudinal drive mechanism is provided to make the vertical slides move on the vertical slides. A horizontal drive mechanism that moves on the horizontal slideway; a support is fixed on the lower side of the front end of the horizontal slide block, and an L-shaped clamping nozzle is hinged on the support through a pin shaft, and the upper side of the L-shaped clamping nozzle protrudes from the horizontal slide The upper side of the block is provided with a spring or a torsion spring that keeps the jaw and the horizontal slide block tightly pressed. 3. The fully automatic microscope continuous detection system according to claim 1, characterized in that: said inclined glass slide transfer device comprises a lifting motor for taking inclined glass slides fixed on the combined frame, and a driving pulley is installed on its rotating shaft, A shaft sleeve 1 is fixed on the combination frame, a vertical rotating shaft 1 is installed in the shaft sleeve 1, and a driven pulley 1 is installed on the upper end of the vertical rotating shaft 1, and the driving pulley 1 and the driven pulley 1 are driven by a belt; The lower end of the vertical rotating shaft 1 is threadedly connected with a lifting slider 1, and a slanting brace is fixed at the lower end of the vertical slider 1, and an oblique pressure plate is hinged on the lower side of the slanting brace through a pin shaft. Pressed by the spring or torsion spring, the pressure plate keeps away from the slanting support plate; at the same time, slideways are fixed in parallel on the combined frame; sliding shafts are symmetrically installed on both sides of the slanting pressing plate, and each sliding shaft is matched and installed on the In the corresponding slideway; the slideway includes an upper section and a lower section with a smooth transition, both sections are parallel to the composite frame, but the width d1 of the lower section from the composite frame is smaller than the width d2 of the upper section from the composite frame. 4. The automatic microscope continuous detection system according to claim 1, characterized in that: the sampling and adding device includes a sampling lifting motor fixed on the combined frame, and its rotating shaft is equipped with two driving pulleys, fixed on the combined frame There are two shaft sleeves, two vertical rotating shafts are installed in the second shaft sleeves, and two driven pulleys are installed on the upper end of the two vertical rotating shafts, and the two driving pulleys and the two driven pulleys are driven by a belt; The lower end of the rotating shaft 2 is threadedly connected with the lifting slider 2, and the lower end of the vertical slider 2 is fixed with a sampling mechanism. 5. The automatic microscope continuous inspection system according to claim 1, characterized in that: a flexible buffer layer is arranged in the pushing groove.